CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483380	Streptococcus equi subsp. zooepidemicus strain NCTC11824 genome assembly, chromosome: 1	3 crisprs	DEDDh,cas3,cas5,cas8c,cas7,cas4,cas1,cas2,DinG,csm6,csn2,cas9	0	18	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483380_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483380_1

566375-567597

TypeI

NA:I-C

Consensus_repeat	Method
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	PILER-CR
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	CRISPRCasFinder
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	CRT
GTCTCGCCTTTCATGGGCGAGCGGATTGAAATAT	PILER-CR

18 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of NZ_LS483380_1

>merge|NZ_LS483380|1|566375-567597|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAATTTTTTGCTAGGGCTTCCGCGTCCCATTTTTGCAAGGTCTCGCCCTTTGCGGGCGAGTGGATTGAAATATAGCCTTAGTTGTTGTTGCTGTAATGGTAGCGTGTCTCGCCCTTTGCGGGCGAGTGGATTGAAATGGCTTTAAAGTGCCTATTGTCGTTGACCAAAACGGTCTCGCCCTTTGCGGGCGAGTGGATTGAAATAGGAACCACGCTGATTGCTTGCGAGTCAAACGGAAGGTCTCGCCCTTTGCGGGCGAGTGGATTGAAATTATGTTTGATAAAAAGCTCGAAGAAGAGGATTATGTCTCGCCCTTTGCGGGCGAGTAGATTGAAATCAAAATGTTGTCAATCAGTACAATTTCGGCCCCTGTCTCGCCCTTTGCGGGCGAGTGGATTGAAATGAGTTTTAAAAGTCAACATCTTTTTTTCGTTTTTGTCTCGCCCTTTGCGGGCGAGTGGATTGAAATATCTTCAGCCTCGGCCAAATACTCCAAAAAATCAGTCTCGCCCTTTGCGGGCGAGTGGATTGAAATTAGGATTGATTTTAGCTCAAAGAGCAGATAGCCAACGTCTCGCCCTTTGCGGGCGAGTGGATTGAAATTTCATCAGTTTTTACAAAACTTGCAACAGTTATGTCTCGCCCTTTGCGGGCGAGTGGATTGAAATACCTCTACTTTATAAAAATCTGCCAACTCATTTAGGTCTCGCCCTTTGCGGGCGAGTGGATTGAAATATGATGACAAAAAAGAGCCGACAGTCGAAGAAATCGTCTCGCCCTTTGCGGGCGAGTGGATTGAAATCATTAAGATATAGATCAAAAGCGTGTTGTAATCGTCTCGCCCTTTGCGGGCGAGTGGATTGAAATCAATCGTTGAAGATCATCATGCCACCGTTTTTAGTGTCTCGCCTTTCATGGGCGAGCGGATTGAAATTTGTTTGATGATATTATTTATCACCTTGTCTGTTGTCTCGCCTTTCATGGGCGAGCGGATTGAAATCTAAGTCCTCTTTGTGACACATCGGGCACACTGGTCTCGCCTTTCATGGGCGAGCGGATTGAAATATCCGATAGGTGATTTTACGGTGCTGACTCTCCAGTCTCGCCTTTCATGGGCGAGTGGATTGAATATGCGATACGTGACTTTACGATGTTGCGACTCCGTTTTGCCCTTTGTGGGTGCGTGGTCCGTATT

>NZ_LS483380|1|1|566375-567269|PILER-CR
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	TTTTTGCTAGGGCTTCCGCGTCCCATTTTTGCAAG
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	ATAGCCTTAGTTGTTGTTGCTGTAATGGTAGCGT
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	GGCTTTAAAGTGCCTATTGTCGTTGACCAAAACG
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	AGGAACCACGCTGATTGCTTGCGAGTCAAACGGAAG
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	TATGTTTGATAAAAAGCTCGAAGAAGAGGATTAT
GTCTCGCCCTTTGCGGGCGAGTAGATTGAAAT	CAAAATGTTGTCAATCAGTACAATTTCGGCCCCT
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	GAGTTTTAAAAGTCAACATCTTTTTTTCGTTTTT
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	ATCTTCAGCCTCGGCCAAATACTCCAAAAAATCA
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	TAGGATTGATTTTAGCTCAAAGAGCAGATAGCCAAC
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	TTCATCAGTTTTTACAAAACTTGCAACAGTTAT
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	ACCTCTACTTTATAAAAATCTGCCAACTCATTTAG
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	ATGATGACAAAAAAGAGCCGACAGTCGAAGAAATC
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	CATTAAGATATAGATCAAAAGCGTGTTGTAATC
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAATCAATCGTTGAAGATCATCATGCCACCGTTTTTAGTGTCTCGCCTTTCATGGGCGAGCGGATTGAAATTT	GTTTGATGATATTATTTATCACCTTGTCTGTT
GTCTCGCCTTTCATGGGCGAGCGGATTGAAATCT	AAGTCCTCTTTGTGACACATCGGGCACACTG


>NZ_LS483380|1|1|566375-567597|CRISPRCasFinder
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	TTTTTGCTAGGGCTTCCGCGTCCCATTTTTGCAAG
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	ATAGCCTTAGTTGTTGTTGCTGTAATGGTAGCGT
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	GGCTTTAAAGTGCCTATTGTCGTTGACCAAAACG
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	AGGAACCACGCTGATTGCTTGCGAGTCAAACGGAAG
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	TATGTTTGATAAAAAGCTCGAAGAAGAGGATTAT
GTCTCGCCCTTTGCGGGCGAGTAGATTGAAAT	CAAAATGTTGTCAATCAGTACAATTTCGGCCCCT
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	GAGTTTTAAAAGTCAACATCTTTTTTTCGTTTTT
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	ATCTTCAGCCTCGGCCAAATACTCCAAAAAATCA
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	TAGGATTGATTTTAGCTCAAAGAGCAGATAGCCAAC
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	TTCATCAGTTTTTACAAAACTTGCAACAGTTAT
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	ACCTCTACTTTATAAAAATCTGCCAACTCATTTAG
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	ATGATGACAAAAAAGAGCCGACAGTCGAAGAAATC
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	CATTAAGATATAGATCAAAAGCGTGTTGTAATC
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	CAATCGTTGAAGATCATCATGCCACCGTTTTTAGT
GTCTCGCCTTTCATGGGCGAGCGGATTGAAAT	TTGTTTGATGATATTATTTATCACCTTGTCTGTT
GTCTCGCCTTTCATGGGCGAGCGGATTGAAAT	CTAAGTCCTCTTTGTGACACATCGGGCACACTG
GTCTCGCCTTTCATGGGCGAGCGGATTGAAAT	ATCCGATAGGTGATTTTACGGTGCTGACTCTCCA
GTCTCGCCTTTCATGGGCGAGTGGATTGAATA	TGCGATACGTGACTTTACGATGTTGCGACTCC
GTTTTGCCCTTTGTGGGTGCGTGGTCCGTATT

>NZ_LS483380|1|1|566375-567533|CRT
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	TTTTTGCTAGGGCTTCCGCGTCCCATTTTTGCAAG
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	ATAGCCTTAGTTGTTGTTGCTGTAATGGTAGCGT
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	GGCTTTAAAGTGCCTATTGTCGTTGACCAAAACG
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	AGGAACCACGCTGATTGCTTGCGAGTCAAACGGAAG
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	TATGTTTGATAAAAAGCTCGAAGAAGAGGATTAT
GTCTCGCCCTTTGCGGGCGAGTAGATTGAAAT	CAAAATGTTGTCAATCAGTACAATTTCGGCCCCT
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	GAGTTTTAAAAGTCAACATCTTTTTTTCGTTTTT
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	ATCTTCAGCCTCGGCCAAATACTCCAAAAAATCA
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	TAGGATTGATTTTAGCTCAAAGAGCAGATAGCCAAC
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	TTCATCAGTTTTTACAAAACTTGCAACAGTTAT
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	ACCTCTACTTTATAAAAATCTGCCAACTCATTTAG
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	ATGATGACAAAAAAGAGCCGACAGTCGAAGAAATC
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	CATTAAGATATAGATCAAAAGCGTGTTGTAATC
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	CAATCGTTGAAGATCATCATGCCACCGTTTTTAGT
GTCTCGCCTTTCATGGGCGAGCGGATTGAAAT	TTGTTTGATGATATTATTTATCACCTTGTCTGTT
GTCTCGCCTTTCATGGGCGAGCGGATTGAAAT	CTAAGTCCTCTTTGTGACACATCGGGCACACTG
GTCTCGCCTTTCATGGGCGAGCGGATTGAAAT	ATCCGATAGGTGATTTTACGGTGCTGACTCTCCA
GTCTCGCCTTTCATGGGCGAGTGGATTGAATA

>NZ_LS483380|1|2|567305-567469|PILER-CR
	TTTTTGCTAGGGCTTCCGCGTCCCATTTTTGCAAG
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	ATAGCCTTAGTTGTTGTTGCTGTAATGGTAGCGT
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	GGCTTTAAAGTGCCTATTGTCGTTGACCAAAACG
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	AGGAACCACGCTGATTGCTTGCGAGTCAAACGGAAG
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	TATGTTTGATAAAAAGCTCGAAGAAGAGGATTAT
GTCTCGCCCTTTGCGGGCGAGTAGATTGAAAT	CAAAATGTTGTCAATCAGTACAATTTCGGCCCCT
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	GAGTTTTAAAAGTCAACATCTTTTTTTCGTTTTT
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	ATCTTCAGCCTCGGCCAAATACTCCAAAAAATCA
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	TAGGATTGATTTTAGCTCAAAGAGCAGATAGCCAAC
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	TTCATCAGTTTTTACAAAACTTGCAACAGTTAT
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	ACCTCTACTTTATAAAAATCTGCCAACTCATTTAG
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	ATGATGACAAAAAAGAGCCGACAGTCGAAGAAATC
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAAT	CATTAAGATATAGATCAAAAGCGTGTTGTAATC
GTCTCGCCCTTTGCGGGCGAGTGGATTGAAATCAATCGTTGAAGATCATCATGCCACCGTTTTTAGTGTCTCGCCTTTCATGGGCGAGCGGATTGAAATTT	GTTTGATGATATTATTTATCACCTTGTCTGTT
GTCTCGCCTTTCATGGGCGAGCGGATTGAAATCT	AAGTCCTCTTTGTGACACATCGGGCACACTG
GTCTCGCCTTTCATGGGCGAGCGGATTGAAATAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483380.1\|WP_024273151.1\|567936_568647_+\|cytochrome-c-biogenesis-protein-CcdA	unknown	unknown	gnl\|CDD\|223856
NZ_LS483380.1\|WP_111692269.1\|558082_560536_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_LS483380.1\|WP_012678332.1\|570688_571429_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|227095
NZ_LS483380.1\|WP_043052850.1\|573183_574272_+\|MmcQ-family-protein	unknown	unknown	gnl\|CDD\|225197
NZ_LS483380.1\|WP_111692271.1\|563379_564228_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|187820
NZ_LS483380.1\|WP_111692268.1\|557132_557456_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373960
NZ_LS483380.1\|WP_037579005.1\|576909_577590_+\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NZ_LS483380.1\|WP_012515211.1\|576295_576769_-\|arginine-repressor	unknown	unknown	gnl\|CDD\|224355
NZ_LS483380.1\|WP_043029462.1\|569307_570420_+\|peptide-methionine-(R)-S-oxide-reductase	unknown	unknown	gnl\|CDD\|184456
NZ_LS483380.1\|WP_111692274.1\|571425_573144_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NZ_LS483380.1\|WP_111692270.1\|560776_561496_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_LS483380.1\|WP_111692907.1\|554979_556110_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483380.1\|WP_043025422.1\|564897_565923_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_LS483380.1\|WP_012515202.1\|565933_566227_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NZ_LS483380.1\|WP_012678328.1\|575247_575736_+\|prolyl-tRNA-synthetase-associated-domain-containing-protein	unknown	unknown	gnl\|CDD\|239827
NZ_LS483380.1\|WP_111692275.1\|574286_574991_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225917
NZ_LS483380.1\|WP_111692272.1\|564229_564901_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|224385
NZ_LS483380.1\|WP_043052835.1\|556091_556481_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483380.1\|WP_111692273.1\|568660_569290_+\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
NZ_LS483380.1\|WP_043030569.1\|561495_563379_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	gnl\|CDD\|187773

Protein	Function_ID	Function_description	E-value
NZ_LS483380.1\|WP_024273151.1\|567936_568647_+\|cytochrome-c-biogenesis-protein-CcdA	gnl\|CDD\|223856	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones].	1.90498e-41
NZ_LS483380.1\|WP_111692269.1\|558082_560536_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	5.1995e-82
NZ_LS483380.1\|WP_012678332.1\|570688_571429_+\|DNA-binding-response-regulator	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	1.34358e-79
NZ_LS483380.1\|WP_043052850.1\|573183_574272_+\|MmcQ-family-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	4.07742e-22
NZ_LS483380.1\|WP_111692271.1\|563379_564228_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|187820	cd09689, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csd2 family.	1.72434e-135
NZ_LS483380.1\|WP_111692268.1\|557132_557456_+\|hypothetical-protein	gnl\|CDD\|373960	pfam15597, Imm59, Immunity protein 59. A predicted immunity protein with an alpha+beta fold and a conserved [DE]R motif. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, which usually contains toxin domains of the Ntox13 or Ntox40 families. In some proteins this domain is fused to the Imm38, pfam15599 immunity domain.	1.02686e-27
NZ_LS483380.1\|WP_037579005.1\|576909_577590_+\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	2.16223e-40
NZ_LS483380.1\|WP_012515211.1\|576295_576769_-\|arginine-repressor	gnl\|CDD\|224355	COG1438, ArgR, Arginine repressor [Transcription].	8.79004e-63
NZ_LS483380.1\|WP_111692274.1\|571425_573144_+\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	9.17555e-63
NZ_LS483380.1\|WP_111692273.1\|568660_569290_+\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.71409e-34
NZ_LS483380.1\|WP_043025422.1\|564897_565923_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_LS483380.1\|WP_012515202.1\|565933_566227_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.21659e-31
NZ_LS483380.1\|WP_012678328.1\|575247_575736_+\|prolyl-tRNA-synthetase-associated-domain-containing-protein	gnl\|CDD\|239827	cd04335, PrdX_deacylase, This CD includes bacterial (Agrobacterium tumefaciens and Caulobacter crescentus ProX, and Clostridium sticklandii PrdX) and eukaryotic (Plasmodium falciparum N-terminal ProRS editing domain) sequences. The C. sticklandii PrdX protein, a homolog of the YbaK and ProX proteins, and the prolyl-tRNA synthetase-editing domain (ProRS-INS), specifically hydrolyzes Ala-tRNA(Pro). In this CD, many of the eukaryotic editing domains are N-terminal and cis-acting, expressed from a multidomain ProRS, however, similar to the bacterial PrdX, the mammalian, amphibian, and echinoderm PrdX-like proteins are trans-acting, single-domain proteins.	6.00337e-60
NZ_LS483380.1\|WP_111692275.1\|574286_574991_+\|hypothetical-protein	gnl\|CDD\|225917	COG3382, COG3382, Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only].	7.00334e-92
NZ_LS483380.1\|WP_043029462.1\|569307_570420_+\|peptide-methionine-(R)-S-oxide-reductase	gnl\|CDD\|184456	PRK14018, PRK14018, bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB.	6.83313e-166
NZ_LS483380.1\|WP_111692272.1\|564229_564901_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|224385	COG1468, COG1468, CRISPR-associated protein Cas4 (RecB family exonuclease) [Defense mechanisms].	3.69546e-30
NZ_LS483380.1\|WP_111692270.1\|560776_561496_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	4.73793e-93
NZ_LS483380.1\|WP_043030569.1\|561495_563379_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187773	cd09642, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-C subtype; also known as Csd1 family.	2.27235e-114

>NZ_LS483380.1|WP_012515202.1|565933_566227_+|CRISPR-associated-endonuclease-Cas2
MMVLVTYDVNTETASGRKRLRQVAKLCVDYGQRVQHSVFECSVTPAEFVEIKHKLTTIIDTEVDSIRFYLLGKHWQNRVETLGRSDSYDPDIGVLLL
>NZ_LS483380.1|WP_043025422.1|564897_565923_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLYLTQEDYYITKEGDNIVIKQDGKTVSRFPFRIIDGVVCFSYLGASPALIKLCTENQINLSFHTPQGRFCGRYVGATNGNVLLRREHYRLADRDESLEYAKRFILAKISNARKYLLRFRRDHRDQIDGKLFEEVNGELIWALEMVQATDNKDSLRGIEGQAANQYFRIFNDLVLTDKKAFTFGGRSKRPPLDRVNALLSFGYSLLTFECQSALEAVGLDSYVGFFHTDRPGRASLALDLVEEFRSYIVDRFVFSLINKGQLTKKHFDVKENGSILLTEKGRVTFIELWQKRKHMEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDIDSYPPFMI
>NZ_LS483380.1|WP_111692272.1|564229_564901_+|CRISPR-associated-protein-Cas4
MVYVEDDYLMLSGIQHFQFCKRQWALIHIDQQWADNEATVHGQILHTRADNPYIREKRKDFFLSRAMHISSARLGLYGVMDVVEFYKDDLGVTVKGKRGRWLPRVVEYKRGKPKKDRRDIVQLVAQTMCLEETLNCQIAEGSLYYHSVNKKIQIAITDELRREVQELANQMHRFYGAKELPKAEYFKNCQLCSLVEVCKPRISKKVRNVDHYIAAAMVSEEII
>NZ_LS483380.1|WP_111692271.1|563379_564228_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MLEHKIDFMVTVEVKEANANGDPLSGNMPRTNAKGYGLMSDVSIKRKIRNRLQDMGQSIFVQANERIEDEFRSLENRFSAQFDKNDKDDDIERRANELWLDVRSFGQVFTYLKKSIGVRGPVSISMAKSLEPVVISSLQITRSTNGMEPKGDSSRSSDTMGTKHFVDYGIYVIKGSINAHFAEKTGFSEEDADIIKQALASLFENDASSARPEGSMRVREVFWFTHSSKLGNVSSARVFDLLVFDMETPDKDCYEAYGIHLDEEKLAAYQAKGLTVEVLEGL
>NZ_LS483380.1|WP_043030569.1|561495_563379_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MDFFTSLLRAYEHAEDIGLVDNQEQSGTILLPIYHTNRRSNGKDTIVVQLDKTGQFMKAEYLADGETIIFPVTAESVARSGKNPAPHPLVDKLTYFVSAHNQEQYETYHQQLEGWINACQDKQVMSYLSLIQQFILKEDFLDLICQSLFGKRLSRNGLKVTYALSEEKEKTVDLSACFLTFQIAQFIGFKTVSVTNFTALHKDYIAYLMSKQTANTICNISGQKEVLATKHRGLLGNAKLISVSNHAEAYKGRFRERDDVFRVGNQTSEKLHLMAKYFLEHEQTHVWLGSGQHMINWFSDDLANDSQLNITQALLLDPFDDEETFLSTPMISEENKSINRSFITGQRQFSDSASYYIAILNKTNDGRIALKYFRQLQASSLLKNLAVWQENYSWELQRKGNQFVQKLPSFKEIILAAYGVDRDRSLELDNDNFRSDQYQRLVTSLIDGKPLPDTIVKKLEANIKQRQKYRKHWHQVEHISLAILHKQNGEEFTPMLDRDNTNRSYLFGRLLGIYELIEKSRNNSKGRAKDELKRITNAERYWTAYANRPASLMRNLEDKIYPYSEYLKINEAGLWSKLEKEREEIIALLTSSLETTDFNKPLDYRFIFGYYAEKKYFYTPKDESEDA
>NZ_LS483380.1|WP_111692270.1|560776_561496_+|type-I-C-CRISPR-associated-protein-Cas5
MRVRGDIALFTNPATKGSSERSSYPVPTRQALQGIVDAVYHKPTITNVVTEVKVINQIQTELHGTRALLKDYGADLSYVSYLSDVEYLIKYHFVWNENRPDLVKDRLPNKHEAIMERSLRKGGRRDVFLGTRECLGLVEAISQEEYETAQIASEHANQEIDLGIMFHSFAYPTDRKEPLRSYFTRTVMTNGRIRFKEQAECEIVNTLSSYTFKPAGPIKPVEEEFEGYQLDTIREAGGQ
>NZ_LS483380.1|WP_111692269.1|558082_560536_+|CRISPR-associated-helicase/endonuclease-Cas3
MILAHYQGETGLTPAKEQSLEEHSFQVAELARAAATSIKQGDLVFLLGLFHDLGKAEYRFQEKLLKKPNSHVDHAYAGARYLYDEIGRVLSDYIRQYPDHKPLVLYFRDIISYVISAHHGMYDLRMTEPAEEASRFAYNKLLHRMFQERPGYHYQKDVFTFVEVLEQSLPRYGYDHLADLITRAFYNFQLAWDKLDMADTSEQDYYSGCFVRLYLSLLKNADVLDTINAYETVIEPLTEEKQEELRISYLEAVESLYASLGQSRLRLNAIRNKLAERVKGRGREDSTGIYRLNLPTGAGKTNLSLRYATHQMVYQQKKHFFYVTPFLSVLEQNALAMKQVIGEEGVLEHHSNVVREIDNANQNNDDTDEDRDSLQREYLIDSWDSPVVLTSMVQFFQTLFKTRSAHLRRFSSLMDSVVILDEVQSLPIEVTTLFNLTMTFLSRVMQTTIVLCTATQPAYDSESITHTLTYGGSKAEEADIVTVTDEEQLAFTRTELCKLSDSDEKTSLVELAQTILEQEMSTLVILNTKPAVERLYQLLRDQTERPLYQLSTNMCPKHRLDVIAEIKSRLPNNVPLICVSTQLIEAGVDIDFERVIRSYAGIDSIVQAAGRCNREGRRPIGQVLLVNLTDDEENLSHLKEIKHKKDATETILYQKTSPIDAVALNDAFFNCYYENNKHRLDYPLGDNETIYQYLSSNAPSNIKKGKLRQAFKTAGQKMDLIQDRSIGVLVFYDDGVGRERLEALEEQLLKSSYPNNEELKAIKAELKALQPYTITLRDNHELLKATRSYLNGQVLFLEERYYHQTFGLTKEADSFIL
>NZ_LS483380.1|WP_111692268.1|557132_557456_+|hypothetical-protein
MDNTNILNWRKEVEEVIKNRGFESLHYVLFDEEKRLPWAFHLYQKNGKFYVEGRDERSYIIGHSKEYHKFNDAKHDLLKKLELVVESNKLKKQLGDPTEYPSPLWNE
>NZ_LS483380.1|WP_043052835.1|556091_556481_+|hypothetical-protein
MERSQLTWEEVSQYEEVKGYGQQVWKHKGEYYLVTNEGGIAEQRVVYELPYDLFQLLEQGKRNLGEIAFKLRYDYWPPNISQEEANRVFWRQYPEVLKNNKNAQKLFTRKELEELLPKGSPILASSDSD
>NZ_LS483380.1|WP_111692907.1|554979_556110_+|hypothetical-protein
MSKTSKALDLQVAGAATPLVVGACVVGSGTVVYGASNLYEAGHNIYLGSVGDGLTVASNPLRDTLFMGNDRLYHQVGGLFTTASAVMIPIGQTKSIAKGLTEFTIGEVGGFIGGQASYHGTKLLGGSEQDAQRATLVGNILGGFAASSAARRFSLNELPTSKSFIDGMSPEDSQRYIQWNKYAKAGLSPSDRVRVLEISEKAPKIEVIDGFNKEQVFKNILSTDKNITRRPNPEEYLKPDYIAAHRHLFDNGAAKFQKFKPNVNYQKGIVGDELGNSFWLSKNHADVIQDVAKGDNRLYETLLGFDEGYLGDGPLYRLDVSPEVVSEKGISIPSGNEKSANSWWRPGGRTYPGDMPEGVMKDISTKKGEHIWSVVN
>NZ_LS483380.1|WP_024273151.1|567936_568647_+|cytochrome-c-biogenesis-protein-CcdA
MELTMLLMVSVFIAGLLSFFSPCIFPVLPVYLGILLDSDDSRSITIFGKKLYWYGIVKTLAFISGLSTIFVILGYGAGLLGNILYAAWFRYLLGAFVILLGIHQMEIVTIKKLQFQKSVAFQNRKDRNAILNAFLLGITFSFGWTPCVGPVLSSVLALAASGGSGAWQGGFLMIIYTLGLGLPFLLLSFASGIVLKHFNKLKPHIPLLKKLGGLLIVIMGLLLMTGNLNSLSGLFE
>NZ_LS483380.1|WP_111692273.1|568660_569290_+|TlpA-family-protein-disulfide-reductase
MKKTTLLTTGLACLALLTACSAKDKMAMTDGKKDHMAMTDHKSKMKKDQKDMMADDKHMSDADKASKNDGQMAPDFELKSIDGKTYRLSDFKGKKVYLKFWASWCSICLSTLGDTQSLATMKDKDFEVLTIVSPGHQGEKSEADFKKWFEGTDFKKLPVLLDPDGKLLEAYGVRSYPTEIFVGSDGVLAKKHIGYAKKSEIEKTLKEIK
>NZ_LS483380.1|WP_043029462.1|569307_570420_+|peptide-methionine-(R)-S-oxide-reductase
MEHKWKLLLLVFGALVFLGGVLMVFQRGYATSYHNNQVKLPAKGTSQLKKTANAKLPEKKKEIYLAGGCFWGVEEYFSNVDGVLDAVSGYANGRGDTTSYQLLHQTGHAETVQVVYDANRISLKELLLHYFRIIDPTSLNKQGNDRGSQYRTGVYYTDPSDLTVIDTVFQEKASDYKKKIVVEKAPLKSFTKAEEYHQDYLKKNPNGYCHINVNEASYPVIDKTKYPKPSKEEIKKKLSKDEYRVTQNNETEKAFSNRYWDSFEAGIYVDVVTGEPLFSSKDKFESGCGWPSFSRPISPDVLRYKTDKSFNMNRTEVRSRSGNSHLGHVFTDGPKDQGGLRYCINSLSIRFIPKAEMEAKGYGYLLTAVD
>NZ_LS483380.1|WP_012678332.1|570688_571429_+|DNA-binding-response-regulator
MYSLLIVEDEYLVRQGIRSLVDFDQFAIDRIAEAENGQVAWELFQENPYDIVLTDINMPKLNGIQLAELIKTRAPKTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKSDVEEMLKKLKQKLEKLKKTEALQKLVDKPQQEGSEIKLAIQERLADSSLTLKSLSSQLGFSPNYLSVLIKKDLGLPFQDYLIQERLKKAKLLLLTTDLKVYEIAEQVGFEDINYFSQRFKQLVGMTPRQYKKGDGQ
>NZ_LS483380.1|WP_111692274.1|571425_573144_+|sensor-histidine-kinase
MKRYPLLVQLVSYFFLIVISLIAILGLIYYQTSSHNIRQLIERETRQSIRQSSQFIDAYIKPLKETTSALANHTSIQAFAKDANSNDQSQVLALMTTVLSTNSDLLSAVLVTKDGRMVTTNPKLTMTTSHDMMAELWYKSAIDRKAMPVLTPARQLSSHSKKDWVVSVTQEVVDQAGNNLGVLRLDIGYNTIKSSLDQLQLGRKGFAFIVNDKHEFVYHPKNTVYSSAKEMAAMKPYLAVTDGYTKSKDYFVYQRVIPDSQWTLIGVASLDQLYHVQRQIFWSFLGTGLLATIICGLGTVFVLRSWIGPIRRLQALILAIQNGNRQLRAEETGSPELADLARQFNAMLDQIDSLMVSVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSQRVVDVTKSLAKYFRLALNQGNEFISLVDELDHARQYLFIQKQRYGDKLHYEIKGLEKYQDFMIPKLILQPLVENAIYHGIKEVDRPGIIRVTVSEADRHVILSVWDNGKGISLADDSSQTLLERGGVGLKNVDQRLRLQYGHLYRMAITSEQAVFTEIKLYLPKALDSLDEAP
>NZ_LS483380.1|WP_043052850.1|573183_574272_+|MmcQ-family-protein
MSLESDYFKRKSPIFEALIPYGFTQEGDTYCYQESFMEGDFKALITIKSSGQLSARVIDTDLGEDYLPLRNDRQQGVYVGQVRQAYLELLGRLSAACFRSTPFQTRQANQVATSISQQWNDPLDYPFEKFPNIATYRVSGKWYAMVLPLLADKLGQVPKVLQGQMVEVLTVRIAPNQLTHLLQQRGVYPAYHMSKKTWISLLLDGTLADDQLWELVTKSRQLANPNGLANPDGPDYWVIPANLSYYDIDAEFAANPDILWTQKASIKAGDYVFIYITAPTRSIRYACQVLRSDIPNQGYRKNAKIKTLMSLRLLHCYEDGLISLDLMKQYGVNAVRGPRRLSPQLVAFLKEKEYFKDVKQKE
>NZ_LS483380.1|WP_111692275.1|574286_574991_+|hypothetical-protein
MTQFIADQSFWELFPDAKLGVLLLRNYDNQEDSPQEVKQLLADSHDIAKQYLTEESFSDNEIIQVYRQAYQRFKTKKGARSSIEALLKRVANGQVLSSINPLVDIYNAASLRFGLPVGAEDSDCFVGDLRLTLTEGGDEFYLIGDSKNSPTLPNELCYKDDAGAVCRCLNWRDGERTMITDRTKNAFLIIEALDSKTQARLQDALKFIEDKAKRYLKAETALYTLDQASPSITL
>NZ_LS483380.1|WP_012678328.1|575247_575736_+|prolyl-tRNA-synthetase-associated-domain-containing-protein
MELFDKVDDTLKALAIDYQLVEHEPALTTEQADQFIEGIEGVRTKTMFLTTRKKNHFYLVIMDDTKRLDMNRFKELVGEKQIKMASAECLLAKMQLPPGVVSPFGLLNNEDKDIQVYVDKAIAHEARMSFHPNTNDKTIFIQTDDLFKFLAAIGYAVNIVDL
>NZ_LS483380.1|WP_012515211.1|576295_576769_-|arginine-repressor
MNKKETRHQLIRSLISETTIHTQQELQERLRKNGISITQATLSRDMKELNLVKVTTGNDTHYEALAISQTRWEHRLRFYMEDALVMLRVVQHQIILKTLPGLAQSFGSILDAMQISEIVATICGDDTCLIICEDNEQAKACFEILSHYTPPFFFSNK
>NZ_LS483380.1|WP_037579005.1|576909_577590_+|Crp/Fnr-family-transcriptional-regulator
MIRREDYQYLRKLDDFCHFSIEQFDKIVGQMEFRQAKKDHMLFFEGDKRDRLFLVTSGYFKIEQSDRTGTFTYTDFIRHGTIFPYGGLFTDDYYHFSVVAMTDVTYFYFPTDLFEDYSLHNQQQMKHLYSKMSSLLELHELKVRNLITSSASSRVIQSLAILLVEMGKDSDTLPFQLTTTDIAQMSGTTRETVSHVFRDLKKSGLIAVKGKYLTYLDKSYFLQYTT

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Crispr_ID: NZ_LS483380_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483380_2

873565-873674

Orphan

Consensus_repeat	Method
CTGACTTGATGACAGCTTATACTAAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483380_2

>merge|NZ_LS483380|2|873565-873674|CRISPRCasFinder
CTGACTTGATGACAGCTTATACTAAAATGCAATATAATTTGTCGTTTGAGTCAATAATAAGATGATAGATCATTACTATTTATCTGAGTTGATGACAGCTTATACTAAAA

>NZ_LS483380|2|2|873565-873674|CRISPRCasFinder
CTGACTTGATGACAGCTTATACTAAAA	TGCAATATAATTTGTCGTTTGAGTCAATAATAAGATGATAGATCATTACTATTTAT
CTGAGTTGATGACAGCTTATACTAAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483380.1\|WP_043038902.1\|876398_877832_+\|spore-coat-protein-CotH	unknown	unknown	gnl\|CDD\|378045
NZ_LS483380.1\|WP_111692389.1\|877838_879977_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483380.1\|WP_111692384.1\|858307_859420_+\|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein	unknown	unknown	gnl\|CDD\|236768
NZ_LS483380.1\|WP_111692388.1\|869703_873426_+\|pullulanase	unknown	unknown	gnl\|CDD\|273973
NZ_LS483380.1\|WP_012678089.1\|875715_876393_+\|DUF4956-domain-containing-protein	unknown	unknown	gnl\|CDD\|379819
NZ_LS483380.1\|WP_012678098.1\|863736_864546_+\|class-C-sortase	unknown	unknown	gnl\|CDD\|320676
NZ_LS483380.1\|WP_111692917.1\|881728_884950_+\|ATP-dependent-nuclease-subunit-B	unknown	unknown	gnl\|CDD\|274291
NZ_LS483380.1\|WP_041790473.1\|864860_866036_+\|YSIRK-type-signal-peptide-containing-protein	unknown	unknown	gnl\|CDD\|370249
NZ_LS483380.1\|WP_111692390.1\|880123_881518_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133045
NZ_LS483380.1\|WP_111692916.1\|875006_875702_+\|molecular-chaperone	unknown	unknown	gnl\|CDD\|143622
NZ_LS483380.1\|WP_111692391.1\|884939_888584_+\|helicase-exonuclease-AddAB-subunit-AddA	unknown	unknown	gnl\|CDD\|274299
NZ_LS483380.1\|WP_111692386.1\|862222_863656_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|374637
NZ_LS483380.1\|WP_111692392.1\|888847_889972_+\|aminotransferase	unknown	unknown	gnl\|CDD\|235989
NZ_LS483380.1\|WP_014622743.1\|874243_874879_+\|membrane-protein	unknown	unknown	gnl\|CDD\|379219
NZ_LS483380.1\|WP_043029632.1\|867677_867863_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483380.1\|WP_111692387.1\|866115_867144_+\|cell-surface-protein	unknown	unknown	gnl\|CDD\|236768
NZ_LS483380.1\|WP_111692385.1\|860243_862208_+\|collagen-binding-protein	unknown	unknown	gnl\|CDD\|377553
NZ_LS483380.1\|WP_012515451.1\|867855_868143_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483380.1\|WP_012678093.1\|868142_868598_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483380.1\|WP_014622742.1\|873714_874254_+\|RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|224511

Protein	Function_ID	Function_description	E-value
NZ_LS483380.1\|WP_043038902.1\|876398_877832_+\|spore-coat-protein-CotH	gnl\|CDD\|378045	pfam08757, CotH, CotH kinase protein. Members of this family include the spore coat protein H (cotH). This protein is an atypical protein kinase that phosphorylates CotB and CotG.	1.3321e-69
NZ_LS483380.1\|WP_111692384.1\|858307_859420_+\|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein	gnl\|CDD\|236768	PRK10819, PRK10819, transport protein TonB; Provisional.	1.0146e-14
NZ_LS483380.1\|WP_111692388.1\|869703_873426_+\|pullulanase	gnl\|CDD\|273973	TIGR02102, alkaline_amylopullulanase, pullulanase, extracellular, Gram-positive. Pullulan is an unusual, industrially important polysaccharide in which short alpha-1,4 chains (maltotriose) are connected in alpha-1,6 linkages. Enzymes that cleave alpha-1,6 linkages in pullulan and release maltotriose are called pullulanases although pullulan itself may not be the natural substrate. In contrast, a glycogen debranching enzyme such GlgX, homologous to this family, can release glucose at alpha,1-6 linkages from glycogen first subjected to limit degradation by phosphorylase. Characterized members of this family include a surface-located pullulanase from Streptococcus pneumoniae () and an extracellular bifunctional amylase/pullulanase with C-terminal pullulanase activity (.	0
NZ_LS483380.1\|WP_012678089.1\|875715_876393_+\|DUF4956-domain-containing-protein	gnl\|CDD\|379819	pfam16316, DUF4956, Domain of unknown function (DUF4956). This family consists of uncharacterized proteins around 220 residues in length and is mainly found in various Bacteroides species. The function of this protein is unknown.	4.76395e-08
NZ_LS483380.1\|WP_012678098.1\|863736_864546_+\|class-C-sortase	gnl\|CDD\|320676	cd05827, Sortase_C, Sortase domain found in class C sortases. Class C sortases are membrane-bound cysteine transpeptidases broadly distributed in Gram-positive bacteria (mainly present in Firmicutes and Actinobacteria). They function as pilin polymerases responsible for the assembly of pili, which are multi-subunit hair-like fibres that extend from the cell surface to promote microbial adhesion and biofilm formation. First, one or more class C sortases form the long thin shaft of the pilus through linking together pilin subunits via isopeptide bonds. The base of the pilus is then anchored to the cell wall by a housekeeping sortase or, in some cases, the class C sortase itself. Depending upon the organism both the number and type of sortase enzymes involved varies, and in some cases, accessory factors appear to be needed. In three-component spaA pilus from Corynebacterium diphtheriae, the prototypical class C sortase (named Cd-SrtA) catalyzes polymerization of the SpaA-type pilus, consisting of the shaft pilin SpaA, tip pilin SpaC and minor pilin SpaB. The pilus shaft is then attached to the cell wall by a housekeeping class E sortase, Cd-SrtF. In the absence of Cd-SrtF, Cd-SrtA attaches the pilus to the cell wall, albeit at a reduced rate. Cd-SrtA can recognize two distinct sorting signals (LPLTG in SpaA and SpaC, and LAFTG in SpaB) and it can employ lysine residues that originate from different proteins (either Lys190 within the pilin motif of SpaA or Lys139 in SpaB). However, Cd-SrtA cannot be able to polymerize the major pilin subunit SpaH, even though it contains LPLTG motif. In two-component pili of prototypical Bacillus cereus, the class C sortase (named Bc-SrtD) cleaves related sorting signals within a major pilin protein BcpA (LPVTG) and a minor tip pilin BcpB (IPNTG), and catalyzes a transpeptidation that joins the threonine residues in each signal to the side-chain of Lys162 in BcpA (located within a pilin motif). Unlike the SpaA pilus in C. diphtheriae, in B. cereus Bc-SrtD is unable to covalently attach the pilus to the cell wall without the help of the housekeeping sortase.	2.20313e-79
NZ_LS483380.1\|WP_111692917.1\|881728_884950_+\|ATP-dependent-nuclease-subunit-B	gnl\|CDD\|274291	TIGR02774, putative_ATP-dependent_exonuclease_subunit_B, ATP-dependent nuclease subunit B. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RecAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. The partner may be designated AddB, as in Bacillus and in alphaproteobacteria, or RexB as in Streptococcus and Lactococcus. Note, however, that RexB proteins lack an N-terminal GxxGxGK[ST] ATP-binding motif found in Bacillus subtilis and related species, and this difference may be important; this model represents specifically RexB proteins as found in Streptococcus and Lactococcus. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_LS483380.1\|WP_041790473.1\|864860_866036_+\|YSIRK-type-signal-peptide-containing-protein	gnl\|CDD\|370249	pfam09028, Mac-1, Mac 1. The bacterial protein Mac 1 adopts an alpha/beta fold, with 14 beta strands and 9 alpha helices. The N-terminal domain is made up predominantly of alpha helices, whereas the C-terminal domain consists predominantly of beta sheets. Mac 1 blocks polymorphonuclear opsonophagocytosis, inhibits the production of reactive oxygen species and contains IgG endopeptidase activity.	2.04058e-38
NZ_LS483380.1\|WP_111692390.1\|880123_881518_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|133045	cd06423, CESA_like, CESA_like is the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.	7.88166e-56
NZ_LS483380.1\|WP_111692392.1\|888847_889972_+\|aminotransferase	gnl\|CDD\|235989	PRK07324, PRK07324, transaminase; Validated.	0
NZ_LS483380.1\|WP_111692386.1\|862222_863656_+\|fimbrial-protein	gnl\|CDD\|374637	pfam16569, GramPos_pilinBB, Gram-positive pilin backbone subunit 2, Cna-B-like domain. GramPos_pilinBB is one of the major backbone units of Gram-positive pili, such as those from S.pneumoniae. There are three major pilin subunits that form the polymeric backbone of the pilin from S. pneumoniae, constructed of three transthyretin-like, CnaB, domains along with a crucial N-terminal domain, D1. The three Cna-B like domains are stabilized by internal Lys-Asn isopeptdie bonds, Gram-positive pili are formed from a single chain of covalently linked subunit proteins (pilins), usually comprising an adhesin at the distal tip, a major pilin that forms the polymer shaft and a minor pilin that mediates cell wall anchoring at the base.	1.04388e-18
NZ_LS483380.1\|WP_014622743.1\|874243_874879_+\|membrane-protein	gnl\|CDD\|379219	pfam13490, zf-HC2, Putative zinc-finger. This is a putative zinc-finger found in some anti-sigma factor proteins.	1.5315e-08
NZ_LS483380.1\|WP_111692391.1\|884939_888584_+\|helicase-exonuclease-AddAB-subunit-AddA	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_LS483380.1\|WP_111692387.1\|866115_867144_+\|cell-surface-protein	gnl\|CDD\|236768	PRK10819, PRK10819, transport protein TonB; Provisional.	1.30141e-11
NZ_LS483380.1\|WP_111692385.1\|860243_862208_+\|collagen-binding-protein	gnl\|CDD\|377553	pfam05738, Cna_B, Cna protein B-type domain. This domain is found in Staphylococcus aureus collagen-binding surface protein. The structure of the repetitive B-region has been solved and forms a beta sandwich structure.	1.08869e-28
NZ_LS483380.1\|WP_014622742.1\|873714_874254_+\|RNA-polymerase-sigma-factor	gnl\|CDD\|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	2.90917e-36
NZ_LS483380.1\|WP_111692916.1\|875006_875702_+\|molecular-chaperone	gnl\|CDD\|143622	cd07750, PolyPPase_VTC_like, Polyphosphate(polyP) polymerase domain of yeast vacuolar transport chaperone (VTC) proteins VTC-2, -3 and- 4, and similar proteins. Saccharomyces cerevisiae VTC-1, -2, -3, and -4 comprise the membrane-integral VTC complex. VTC-2, -3, and -4 contain polyP polymerase domains. For S. cerevisiae VTC4 it has been shown that this domain generates polyP from ATP by a phosphotransfer reaction releasing ADP. This activity is metal ion-dependent. The ATP gamma phosphate may be cleaved and then transferred to an acceptor phosphate to form polyP. PolyP is ubiquitous. In prokaryotes, it is a store of phosphate and energy. In eukaryotes, polyPs have roles in bone calcification, and osmoregulation, and in phosphate transport in the symbiosis of mycorrhizal fungi and plants. This subgroup belongs to the CYTH/triphosphate tunnel metalloenzyme (TTM)-like superfamily, whose enzymes have a unique active site located within an eight-stranded beta barrel.	2.93368e-64

>NZ_LS483380.1|WP_111692388.1|869703_873426_+|pullulanase
MMKRLRENQALFEERQLFGIRKLKLGVASVAIAAAFSLGTASGHTTVAAESLTSVEPIDGAVMVKSGAADQEQGSNELPEATDISDIAGTSDVTKVSAAVNADTVKEVQPVAVPLVEDQAQEETTDQSQPSSSIVPVTTDSSLETPEATSSEAPIAAQTLRLHFKTLPAQDLSSLGLWVWDDVETPSDQLGGWPTGATNFSLAKTDDYGYYMDVKLSAEQANKVSFLINNTKGDNLTGDRTIDLLSPKMNEVWIDGQELSYYPPLAQGYIRINYYRSDGHYDNKSLWLWGSADASMTSQQGAWPDGIDFKQVGRYGAYIDVKLADFNELGFLLLDERQTGDAVKIQPNDYIFKDLKNHTQIFLKDEDPTIYTNPYFVNHVRLIGAKQVSPSSIEASFTTLADVDKESLLKELKISTDSKEAVAITDITLDEKTHKAVITGDFSQAVATYTVTFHHESFQARPNWQYKDSLYAYDGELGARVREAGAKVDLTIWSPSADKVSLVLYDKADQTKVIGNLALAKGDKGEWSITLSADSGLGISDYRGYFYHYEITRNGKSVLVLDPYAKSLAAWNSELAKTDPSYKVAKAAIVDPAAIGDKELAFADIKGFHKREDAIIYEAHVRDFTSDQAIANDLKAQFGTFAAFVEKLDYLKELGITHVQLLPVMSYYFVNELANKERMLTYSSSDNNYNWGYDPQSYFALTGMYSTDPTDPAKRIEEFKQLVNEIHKRGMGVILDVVYNHTANVDIFEDLEPNYYHFMNADGTARTSFGGGRLGTTHYMSRRVLVDSITYLVDEYKVDGFRFDMMGDHDAAAIEKAFLAAKALNPNIIMLGEGWVTYQGDEHMPEQPADQSWMSQTDTVASFSDDFRNQLKSGFPNEGSPAFITGGARDIMTIFHNIKAQPTNFLADDPGDVIQYIAAHDNLTLFDIIAQSIKKDPSVAANAAEIHRRLRLGNLLVLTSQGTPFLHAGQEYGRTKQFKDEAYKGKVADDKVPNKSHLLVNENGIPFEYPYFIHDSYDSTDAINHFDWAKATDTERYPESTRSQAFTKGLIALRRSTDAFRLASKAEIDQKVKLITVPNEHGIKAQDLVIAYQTTASNGDVYAVFVNADSNDRTIRLTGEFQALLAGEVIVDAKQAGTEALASPEGVVLTKDGVKLSGLTATIIRLRASQSDKGTLGAMTDQAAHHQEKLVAAQTAGEVSQFSAKTLPKTGTSQLDALLALAGSGILAGLGGLVSKSKRR
>NZ_LS483380.1|WP_012678093.1|868142_868598_-|hypothetical-protein
MVKHAKTNLHFELERSISRKVDSKLIAYQVSLSDGFYDKYTKLWDKTYSFDFVINHRAFYAQLTKRCVYDVLLQTLEKISRKAIAKQLAELEALVDVSESKEDFQIFFEKKYKLSFPDLKNCVYPKKKELSDFDQNLWIALHYNPRKERDT
>NZ_LS483380.1|WP_012515451.1|867855_868143_-|hypothetical-protein
MTTWYDYMVRASEHAGSDGDLWFRYLYKIIKDGETKLTTDDVEQLLKNPNLTPFQKVTLQDALTEGTHTREHVLQANRKSQPKDILKLFREGNYG
>NZ_LS483380.1|WP_043029632.1|867677_867863_-|hypothetical-protein
MDKKILFKALNTELAKENISLDIICVGGFVLEYYNLRGTQDVDAFYQEGVNIRQMIKKGWR
>NZ_LS483380.1|WP_111692387.1|866115_867144_+|cell-surface-protein
MLTNQTGYRHRLSKQKLPISMVSCLLGMGVFISPTSISADSPPTITIKSAADKDISSNLLKAPLSNAKPEEKLEDTPQLPNEKGQGDDIREPEKLPELPNEKGQGDDLKKDEDLKKQRRELTEKLRGLKTVEEVLEFLKMPIPGFVTDVDWQFLMAFVEKGTANKTFEKDKLTLLDIYSTSSGHMIWLGYLVPEKPEPMPEPKPEPMPKPEPKPEPMPKPEPMPKPEPMPKPEPMPKPEPMPKPMPKPEPMPKPMPKPEPMPKPMPKPEPMPKPEPMPKPEPMPKPMPKPEAQKGDKPVVPKAMEHKLPSTGEATAPFFTAAALAVLASLGVAVVSRKRKKH
>NZ_LS483380.1|WP_041790473.1|864860_866036_+|YSIRK-type-signal-peptide-containing-protein
MKKQSFTHSRKPKFGMRKLSIGLASCMLGMMFLTTSHVSGEVVEVWPYGQDPNDKIEVLSQSEYSEYLQRLHDVEDFQAEKKKEGVVRTQWLEGVNVTDHDFRKITDGGSVYYATPLLNDRGYYDINKNFNQDSDKCAAAVAVNMFHYWLDRNKDNVAKFLSQSPDHGFVEGEPTFNLVDFQYTYASPYEEGGYRDNSKLFDFISKAFNKPLWANKLLDAYINGYGYIDRYVKNTPHSGQNNSKFNFFKKVFDGKLLTDIQQIFDYYTLSSELREALDTGKAIGLAYGPGDLRRSLGHIISVWGADINEDGNVVAIYVTDSDDKKLTIGNKKDRIGLKRYKLYSDNVGRARLTAYATENQQTGGEVRGIETLDMATQDWADYFSRTDEAEQ
>NZ_LS483380.1|WP_012678098.1|863736_864546_+|class-C-sortase
MKKSVIFWSVILVAGCLIVLYPTLSNYWNAQHQSQLIADYISSTQALRHKDSQLMLEAANQYNQQLKANHDPDLTLTDSEAEAYQQQLDLTNTGIMAYIDIPKVHERLPIYHGTDEEILQVAIGHLAGTSLPVGGKGTHAVISGHRGLPSAKLFTNIDKLRINDTFTITSLNRTMTYQVDKIATVLPDDVSLLRIEEGKDLVTLVTCTPYGVNTHRLLVRGHRIKTATPAAARGSQKPSRLILWLLLISALGLSLVLIGTWRWRRRSKA
>NZ_LS483380.1|WP_111692386.1|862222_863656_+|fimbrial-protein
MKTIKLILTSLLVTFLTMLSGKAFADTASYTITVEGATAGHTYEAYQIFKGDLFDSTLSNITWGGGVTPFEFDGSKDAAKIAEGLKEANAADFAKEAGKHLTTVVAGQGEQTITVNEAGYYLIKDKNDSQTGKHDAYTSFVLKVVKNTSFKPKSAIPTVLKKVKDRNDKTGLETDWQDSADYDKNDKVPFQLTATLPSNYDAFQEYYLEFVDTLSKGLSYNKDAKVYVINGDSRQDITGSFTINESGSSFKINNLKTVTDVTADSKIVVEYTATLNDQAAIGKKGNPNEVALKYSNDPNALGKGEESPKGETPKDKVIVFTYKTIINKVDQDKQALKGAGFTLYKLVKTADKEEYQKVQEIKAGDTTSFEFVGLDAGDYKLSETTTPGGYNTIADVMFSIVAQHETESDDPQLTSLTVDKATGFTADTEAGTVSATIVNKKGSILPSTGSIGTTMLYVFGVMLMTISTLFIFRQKQQ
>NZ_LS483380.1|WP_111692385.1|860243_862208_+|collagen-binding-protein
MKQLTKIVSVVLLLVFTLSASLHKVRATNLSDNITSLTVASSSLRDGERTTVKVAFDDKKQKIKAGDTIEVTWPTSGNVYIQGFTKTIPLMINNINVGILEVTLDKAVFTFNENINTMENVTGWGEFEITVRNVTQTTTETSGTTTVRVGNHTATITVTKPEAGTGTSSFYYKTGDMQPDDTDHVRWFLLINNNKEWVANTVMVEDDIQGGQTLDMSSFDITVSGYRNERFVGEKALEEFRQKFPNSVITATANHISVRLDQYDASQNTVNIAYKTKITDFDQKEFANNSKIWYQILYKDQVSGQESNHQVANVNANGGVDGSRYTSFTVKKIWNDKENQDGKRPKNIKVQLYANNKEVEGKVIELNDSNSWQASFGKLDKYDSQNQKITYSVKEVTVPTGYQSQVEGDSGAGFTITNTYTPEMISITGQKTWDDKENQDGKRPKEITVCLLANDAATDKVATASEQTGWKYAFTNLPKYKDGKQITYTIQEDPVADYTTTIRGFDITNHHEVALTSLKVIKAWNDKDDYYHKRPKEITILLKADGKVIREHQLTPDQQGKWEYTFDKLPVYQAGKKISYSIEEKQVDGYQAPVYDINEDLNQVTVTNTINPSYQLPDTGGQGVKWYLLIGGGFIIVACLVLINLYQKHKHHNM
>NZ_LS483380.1|WP_111692384.1|858307_859420_+|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein
MAKKEMKYYLRKSAFGLASVSAALLVGAASVSADSVESAGPVAVAVTDSLDSEAAATKAEADLVAAKAELAAAEAAITAAKADFDTAQADLATAEATIAELEQKIPELEKKIQEVQEKLNYENRLSPERVGSDDEDDTEARRLIAEKEALKAELQKTKEALDTAKKAYAGIEERKQVAAAKLDAANKAFAGVEEKHAQAMAKFAEAFAAYKEAVKAELKAAGASDFYTKKIDSANTVAGVKTLREMILDSIAKPEVEPEAKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPKPQPKPAPAPKPEAKKEEKKAAPKQDANKLPSTGEATNPFFTAAALAVMAGAGVAAVSTRRKEN
>NZ_LS483380.1|WP_014622742.1|873714_874254_+|RNA-polymerase-sigma-factor
MIKGVLRGDKLLEFEDIYLEYKDDVYRFVNKLCCYQNSLSDDITQETFLKAYRNIAKFRGDSSIKTWLFTIAKNTFFTEIKKKKYENMSMESLEIVDAKEHDEPLDKIERRELLEITLTIIFNLPEKMQAVFLARIYSGDSYEKIAKDIGITVSSAKVLVFRARKHIKRQLREEYGYEV
>NZ_LS483380.1|WP_014622743.1|874243_874879_+|membrane-protein
MRYDCELIQDLLPLYVDDTLSDYSRAVVEAHLTSCKDCQIDLADLRQDYSKVEEELQEYQAEVCAFSRFIRKQRQQMIVATISICLVTGILSSILTAHRIQAPYDYVAIDVGEHTQLNKEGLLSTARTTAKDHVALVYKHKAQKVNGSFEISELQARKIQQQLKQAMLKEANATDISSRQLDQSQKRLSCNQDDQLVYIISTDGRIYYFGR
>NZ_LS483380.1|WP_111692916.1|875006_875702_+|molecular-chaperone
MNEVLRQEKKYLITIEDYYRLSHEFSKLLRLDAHSSSEGYVIRSLYFDSLEDVDWQEKEDGIELRRKIRLRNYGSQSSFAKLEMKQKQGSHQKKRSLRLTRADAQLLIKGDRSILLAYPDRFAAECYSRMSMQLYQPKTVIEYQRKAFVAKENNIRITFDHHIIGSETNADIFSDHLPQNYLLDPYLVILEVKYNGFLLSYIKKLLESVNGSELSASKYCMGRAISKHYRF
>NZ_LS483380.1|WP_012678089.1|875715_876393_+|DUF4956-domain-containing-protein
MKQLLRHVFEQRGTLSFQDVLLHIVAAALLSIVIYMSYAYTHTGTAYSKKFNVSLMTLTVLTATVMTVIGNNVALSLGMVGALSVVRFRTAIKDSRDTVYIFWTIVVGICCGVGDYTVAATGSSVIFMLLLLMGAVRNDNRLLLIVRCDKQMEIELERLVFNYFSGKAIQRVKNTTSDDIEMIFELSRKDYDSTYQQDNPLTEAVYQLGRVDYFNIVSQSDDITG
>NZ_LS483380.1|WP_043038902.1|876398_877832_+|spore-coat-protein-CotH
MKEKTIYVIVLVCLLLAAICGIGFPKTSAKRIHHHLQTVKKSSRSAGEFSSHLPIISIDTHHQQIPEQREYEGETKRQKTIKTTVSLRDQLDREHSLSESPRLSLTALIAYRGNSSRHFDKKSLKLRFINKSAKPKAVSLAGMSKESEWVLHGPFLDRTLVRNYLSYNIAGEIMTYAPNVRYCELVVDHQYCGLYLAVESIEQGRHRVNIEKSDRKSDKTPYILVWDRRHKAKQALDHYVSYTNQAGLSSLDIKYPSLHRLTPKQKQFIEKDISHIEKLLYSYDLKQYTDYLDQESFADYFIINEFFRNIDAGKFSTYLYKDLRDKLKLVVWDFNNAFDNQIEAPYDEADFTLSDAPWFCMLLKDPSFVKLVVTRYHQLRQNVLSTDYLIKYIDATVAFLGPAIQRNYHKWGYVFTVPSRSDATNYLVPASRNYSSYKASVKQLKDFIRRRGRWLDKHIETLYQYSAPSKNTNTLLE
>NZ_LS483380.1|WP_111692389.1|877838_879977_+|hypothetical-protein
MKKYLIFVGLLLSVIGLSYYCCDIDGRLYLPVSNQSAIRTVFYIKDKRIYDQKGSPYLIKGVDVESSIAGYRQRDLSVDEKTYYRWFKQIAAMGANTIRVRVIMSAAFYHALSRYNDRASHPLYLLQGFRIDAYHDNSSISALDKAYLGTLLREARASVDVIHGRKRIWHSDLGLQHYDQDMSKWLIGYIVGDDWHSGTIAYTNHQNQSKPVGFKGRYYATTPQANRFEAVLAEIMEEITSYESHKYGWQHLVSFSNTPQSDPFVYQDPFASQAAKYVQLTIENIKPSAKVKAGLFASYKLLDCHSAYRDYLLFDRLGLDDRLVGDIKRMPLYQGYVKLLTSYHRVPVVVTGYGYSTARGVDQMISTSSPLTEKDQGERLMADYTAFIASGCCGATIHSWQDDWTARSWNTSFATNKHQSFLWGDVQSKAQGYGLLTFEHAPRTHAIDGQKAASEWSKALIYRKNGHQLLVDQDEKYLYIAIEATQQPLQRQWLIPLDITPKTGSRVIEGLSARFDRFADFALVVDDHKGSRLLVQERYHATDANYLRQINGKDFYVFPPNKHTPRFTMVDMVVRNDGIFAAIDQVPIAKRGLKRYPTGQLKQGNGKRGSAHFDSQTDISFGERLIELRIPWQLLNFSDPASNKIHDDYFEHYGVEELAIEAIAIGFAPLKESKVITMIEYPLLSWERPRVREVLKTSYRQVQAVWQEKRRK
>NZ_LS483380.1|WP_111692390.1|880123_881518_+|glycosyltransferase-family-2-protein
MQLLFLVLKYSQYLFLAFLIAYASFLLLSLIVGAIHLYERRQQVPLGDAVSLPPVSILVPAYNEALTIIETVESLLMLDYGCYEIIVIDDGSTDHTAKLLKERFHLEAVTCSINQRIPTRPLKAVSQKQLEHVRLTLLEKENGGKGDSLNLGINAAQYDYFLCMDADSMLQEDSLKRIAKTAAKDPSVIAVGGMVKVSQGVALAAGRIVDYHLPRQLISCAQAIEYDCAFFGARVLLDQAAGNLIISGAFGLFKKELAIAVDGYDTGTLGEDMELVMKLHFFCQNNKIPYRIGYETDAICWSQAPSRLKDLCQQRRRWFLGLYQCLKKYLQFFVSCRFKATVLISYVLYLLFELLSPFIETFGVTIIVLSLLCHQLNTTFFVSLMLLYICYCVLIALTSFLNRVYSQNNSSITFFDMVWVIYAAIYQCLVLHTVLTLVKVSSFIGYQRKKNAWGQITRDKHKAA
>NZ_LS483380.1|WP_111692917.1|881728_884950_+|ATP-dependent-nuclease-subunit-B
MKLLYTEISYSMTEILVKEARAYADKGYRVFYIAPNSLSFEKERSVLALLPEQGSFAITVTRFEQMARYFTLAKAANRKALDDNGLAMIFYRVLMQLQEEELKVFHRLRTDQAFIAQLVELYKELQAANLTAFDLTTLDRPEKQEDLITIMTKAEQLIAQGDYDQSSRLAQLAEAIKSKSLDDELRQTVLVIDGFTRFSAEEEQLLALLNEACEEIVIGAYISQKAYRLAFTKGNLYEASLAFIQQLAQQFQTKPIYTTSEKVFDVSFSRLTQLLEANHDYSQLDWQLSAKDKSKVVIWQALNQKEELEHVAKAIREKLYQGYRYKDMLVLLGDVASYQLQIGPIFEKFEIPYYIGKQEPMSAHPLVQFVESLERGRRYNWRREDIVNLLKSGLFGRFQEGELDQLEQYLVFADIQGFTKFSRPFTLNSSRQYPLPLLNQLRLAVVTPLQQLFKSQKQLGASLLDKLMTFFKTIRLADNFEALAGSRREADREKDEEVWKAFTGILETFYQVFGQEKMTLADCLALIKMGMQTAHYRTVPATLDVVSIKSYDLVEPHSKPFVFAIGLSRSHFPKQTKNTSLISDQERASINEQTASYQRLDVPSFENIKKNHQTALSLFNAATQELVLSLPTSLTNSSDDVSPYLKELIALGVPVIEKGKNRLSHSAADIGNYKALLSRLVAINRQGIADDMTSEDRNFWTVALRYLKRRLADEQLSLPAFEHHLTTKPVAPEVIETRFPSHQPLSLSSSALTVFYNNQYKYFLKYVLGLQEPESIHPDARIHGQYLHRIFELVTKDRTDAAFDQKLGAAIAAVNQQSAFQQVYQADAEGRYSLEVLKGIAYSTAPVLNLNQGMQVAKQEEAFELALGHQALIRGVIDRIDQLADGRLGIVDYKSSARVFDIGAFYNGLSPQLVTYLAALKNKGQGLFGAMYLHMQEPRLSLSDFKVLDDQLVAAAYKELTYKGIFLAQAKEYLANGSYHLNNTLYETDELETLLAYNEQLYLSAVKQIKTGHFLINPYTADGKSVQGDQLKAITRFEADLDLGYARRLVVLPVKERRQAFLTRMNEEIKHED
>NZ_LS483380.1|WP_111692391.1|884939_888584_+|helicase-exonuclease-AddAB-subunit-AddA
MRIDEGFLTPEAIARLQQEEALSDKTHKRTAQQIEAIYSSGQNILVSASAGSGKTFVMVERILDKILRGIPVDRLFISTFTVKAATELIERIEKKLHTAIAETQDYQLKAYLNDQLQALSQADIGTMDAFAQKLVHQHGYVLGISPHFRTIQDKAEQDILKREVFRQVFEDYMSQTDNKAFIQLVQNFSGRRKDSSAFREIVDSIYAFSQSTANPSSWLAEVFLRGSKTYTSFADIPDQAVDTLLACMQDTADQLRDLTDMEGYAQTTKAGKLTAKYTKHLKMIDSLYEWALHFDSLYGKARLGQLAQELTALLPSGADITVAGHKYPIFKSLQEQLVGFRHLETILAYQQESLPLLEVLQAFVISFSEAYLAAKMQENAFEFSDIAHFAIEILQQAPDIRQAYQGHYHEVMVDEYQDNNHMQERLLELLSNGHNRFMVGDIKQSIYRFRQADPQIFNQKFKDYQSNPEHGKLILLKENFRSQSEVLNVTNAVFSRLMDESLGEITYDDKHQLVAGSEVQKQLHPENRAQLLLYNTDQAQEGTEEASTNDGISAGEVTLVAKEIIRLYNEEKVAFEDITLLVSSRTRNDTIFQVFNQYGIPLVADGGQENYLKSVEVMVMLDTLRSINNPLNDYALVALMRSPMFSFDEDQLARISLQSSSQDQPQAFYDKLSNSLRGQGEHPGLIGQELMTKLVDFDRTLRDWRQFAKLHSLYELIWKIFNDRFYFDFVASQPKAEQAQANLYALAIRADQFEQSGYKGLSRFIGMIDKVLETQNDLADVEVERPKHAVNLMTIHKSKGLEFHYVFILNCDKRFAMADLQAPIILNRDEGIGIKYVANVKELLRDEKLASLKVTMETLPYQLNKQQLRLATLSEQMRLLYVAMTRAEKKVYLVGKASKEKIQAKTADNSSEGRLALASRERLLSFQDWLLAITATFSKEDLFIDVRFVDDSDLTAEAVGQLRSSGLLQADDLKDNRQTEDIARALDMLDKVSKLNASYQAAIELPTVRTPSQLKTLYEPLMDTDGVDIIDQPYHRPKSFELPDFSKKKAVEPSQVGSSLHELMQRIPMSDQVTAGDIEQALQLVSADAEVKARLDIEKVTAFFATTELGKLLQEHHQRLYREAPFAILKKDSLSQEQYVVRGIIDGYLLFEDRIVLFDYKTDHYQYSAELKQRYQQQMGLYAEALSQSYGIARIEKYLVLMGGSQLEVVRLDE
>NZ_LS483380.1|WP_111692392.1|888847_889972_+|aminotransferase
MKLPVFGVEEWLNQHEKSAVYDIAGSSIASLTLEELFDLTQEQPQVFYQQLHQKPLDYGWIEGSPDFKQAVAGLYQQQKARNILQTNGATGANFLVIYALLEAGDHVIAHYPSYQQLYDIPASLGVEVDYWQIREEQAWLPDLNELGAMIRPNTKMIMINNANNPTGAYMTKPYLEELINIAREHDIYLLSDEVYHSFASDHLLAVADLYDKGISVNSMSKTFSIPGIRVGWVAASETICDQLRLYRDYTMICAGVFDDMVASLALKHADKLLQRNQAIIRTNLAILEDWITGEAKASYIKPSEVSTAFVRLDIDEDIEAFALRLLEDYGTLVVPGNRFNQANHVRIGYCCQPQVLQAGLSRLSQCLKKYSIKA

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Crispr_ID: NZ_LS483380_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483380_3

1382051-1382481

TypeII

II-A,II-B

Consensus_repeat	Method
GTTTTGGAACCATTCAATACAGCATAACTCTAAAAC	CRISPRCasFinder
GTTTTGGAACCATTCAATACAGCATAACTCTAAAAC	CRT
GTTTTGGAACCATTCAATACAGCATAACTCTAAAAC	PILER-CR

6 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_LS483380_3

>merge|NZ_LS483380|3|1382051-1382481|CRISPRCasFinder,CRT,PILER-CR
ATATTAAAACTATTCAAAACAGCATAACTCTAAAACCTTTGAAACGATTTCTAATGACATTTAAATGTTTTGGAACCATTCAATACAGCATAATTCTAAAACTATCATAAGACTGATAATGCGTAATACTTAGTTTTGGAACCATTCAATACAGCATAACTCTAAAACTGTCTTGCTTCTGATTGAAGTTCAGGGCAGTTTTGGAACCATTCAATACAGCATAACTCTAAAACTTGTATATGGTAATACCTTTGGTTGTACGTGTTTTGGAACCATTCAATACAGCATAACTCTAAAACAGGTCGTTTTGATGGATTGGAGACACATGAGTTTTGGAACCATTCAATACAGCATAACTCTAAAACAATCAGTTGAATCTAAAACAACCTGACACTGTTTTGGAACCATTCAATACAGCATAACTCTAAAAC

>NZ_LS483380|3|3|1382051-1382481|CRISPRCasFinder
ATATTAAAACTATTCAAAACAGCATAACTCTAAAAC	CTTTGAAACGATTTCTAATGACATTTAAAT
GTTTTGGAACCATTCAATACAGCATAATTCTAAAAC	TATCATAAGACTGATAATGCGTAATACTTA
GTTTTGGAACCATTCAATACAGCATAACTCTAAAAC	TGTCTTGCTTCTGATTGAAGTTCAGGGCA
GTTTTGGAACCATTCAATACAGCATAACTCTAAAAC	TTGTATATGGTAATACCTTTGGTTGTACGT
GTTTTGGAACCATTCAATACAGCATAACTCTAAAAC	AGGTCGTTTTGATGGATTGGAGACACATGA
GTTTTGGAACCATTCAATACAGCATAACTCTAAAAC	AATCAGTTGAATCTAAAACAACCTGACACT
GTTTTGGAACCATTCAATACAGCATAACTCTAAAAC

>NZ_LS483380|3|2|1382051-1382481|CRT
ATATTAAAACTATTCAAAACAGCATAACTCTAAAAC	CTTTGAAACGATTTCTAATGACATTTAAAT
GTTTTGGAACCATTCAATACAGCATAATTCTAAAAC	TATCATAAGACTGATAATGCGTAATACTTA
GTTTTGGAACCATTCAATACAGCATAACTCTAAAAC	TGTCTTGCTTCTGATTGAAGTTCAGGGCA
GTTTTGGAACCATTCAATACAGCATAACTCTAAAAC	TTGTATATGGTAATACCTTTGGTTGTACGT
GTTTTGGAACCATTCAATACAGCATAACTCTAAAAC	AGGTCGTTTTGATGGATTGGAGACACATGA
GTTTTGGAACCATTCAATACAGCATAACTCTAAAAC	AATCAGTTGAATCTAAAACAACCTGACACT
GTTTTGGAACCATTCAATACAGCATAACTCTAAAAC

>NZ_LS483380|3|3|1382117-1382481|PILER-CR
GTTTTGGAACCATTCAATACAGCATAATTCTAAAAC	TATCATAAGACTGATAATGCGTAATACTTA
GTTTTGGAACCATTCAATACAGCATAACTCTAAAAC	TGTCTTGCTTCTGATTGAAGTTCAGGGCA
GTTTTGGAACCATTCAATACAGCATAACTCTAAAAC	TTGTATATGGTAATACCTTTGGTTGTACGT
GTTTTGGAACCATTCAATACAGCATAACTCTAAAAC	AGGTCGTTTTGATGGATTGGAGACACATGA
GTTTTGGAACCATTCAATACAGCATAACTCTAAAAC	AATCAGTTGAATCTAAAACAACCTGACACT
GTTTTGGAACCATTCAATACAGCATAACTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483380.1\|WP_111692591.1\|1391927_1392350_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483380.1\|WP_014623135.1\|1372970_1373729_-\|triose-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
NZ_LS483380.1\|WP_021320955.1\|1367977_1369279_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NZ_LS483380.1\|WP_042670905.1\|1379579_1380668_-\|membrane-protein	unknown	unknown	gnl\|CDD\|379376
NZ_LS483380.1\|WP_012515930.1\|1383764_1384634_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_LS483380.1\|WP_111692588.1\|1382756_1383431_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_LS483380.1\|WP_111692593.1\|1394742_1395522_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483380.1\|WP_111692589.1\|1384633_1388680_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_LS483380.1\|WP_111692590.1\|1390206_1390953_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370193
NZ_LS483380.1\|WP_043026121.1\|1369503_1370313_+\|sugar-phosphatase	unknown	unknown	gnl\|CDD\|182509
NZ_LS483380.1\|WP_111692585.1\|1371526_1372762_+\|peptidoglycan-branched-peptide-synthesis-protein	unknown	unknown	gnl\|CDD\|367067
NZ_LS483380.1\|WP_012677692.1\|1380651_1381122_-\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|274361
NZ_LS483380.1\|WP_111692592.1\|1392952_1394128_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379424
NZ_LS483380.1\|WP_111692587.1\|1381508_1381688_+\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_LS483380.1\|WP_111692586.1\|1376139_1379286_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367432
NZ_LS483380.1\|WP_012515937.1\|1392539_1392944_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|317917
NZ_LS483380.1\|WP_012678588.1\|1389190_1389514_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373960
NZ_LS483380.1\|WP_111692584.1\|1370312_1371527_+\|UDP-N-acetylmuramoylpentapeptide-lysine-N(6)-alanyltransferase	unknown	unknown	gnl\|CDD\|225224
NZ_LS483380.1\|WP_012515923.1\|1373994_1375191_-\|elongation-factor-Tu	unknown	unknown	gnl\|CDD\|234596
NZ_LS483380.1\|WP_021320962.1\|1383423_1383768_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043

Protein	Function_ID	Function_description	E-value
NZ_LS483380.1\|WP_014623135.1\|1372970_1373729_-\|triose-phosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	3.45341e-146
NZ_LS483380.1\|WP_021320955.1\|1367977_1369279_+\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.31853e-157
NZ_LS483380.1\|WP_042670905.1\|1379579_1380668_-\|membrane-protein	gnl\|CDD\|379376	pfam13800, Sigma_reg_N, Sigma factor regulator N-terminal. This domain is found near the N-terminus of a sigma factor regulator. The N-terminus is responsible for interaction with the sigma factor.	4.00303e-11
NZ_LS483380.1\|WP_012515930.1\|1383764_1384634_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	6.18158e-127
NZ_LS483380.1\|WP_111692588.1\|1382756_1383431_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	3.37659e-111
NZ_LS483380.1\|WP_111692589.1\|1384633_1388680_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_LS483380.1\|WP_111692590.1\|1390206_1390953_-\|hypothetical-protein	gnl\|CDD\|370193	pfam08929, DUF1911, Domain of unknown function (DUF1911). This domain is found in a set of hypothetical bacterial proteins.	8.10337e-31
NZ_LS483380.1\|WP_043026121.1\|1369503_1370313_+\|sugar-phosphatase	gnl\|CDD\|182509	PRK10513, PRK10513, sugar phosphate phosphatase; Provisional.	7.64259e-107
NZ_LS483380.1\|WP_111692585.1\|1371526_1372762_+\|peptidoglycan-branched-peptide-synthesis-protein	gnl\|CDD\|367067	pfam02388, FemAB, FemAB family. The femAB operon codes for two nearly identical approximately 50-kDa proteins involved in the formation of the Staphylococcal pentaglycine interpeptide bridge in peptidoglycan. These proteins are also considered as a factor influencing the level of methicillin resistance.	3.02016e-165
NZ_LS483380.1\|WP_012677692.1\|1380651_1381122_-\|DNA-binding-protein	gnl\|CDD\|274361	TIGR02950, RNA_polymerase_ECF-type_sigma_factor, RNA polymerase sigma factor, SigM family. This family of RNA polymerase sigma factors is a member of the Sigma-70 subfamily (TIGR02937) and is restricted to certain lineages of the order Bacillales. This family encompasses at least two distinct sigma factors as two proteins are found in each of B. anthracis, B. subtilis subsp. subtilis str. 168, and B. lichiniformis (although these are not apparently the same two in each). One of these is designated as SigM in B. subtilis (Swiss_Prot: SIGM_BACSU) and is activated by various stressors.	7.76752e-22
NZ_LS483380.1\|WP_111692592.1\|1392952_1394128_-\|hypothetical-protein	gnl\|CDD\|379424	pfam14021, TNT, Tuberculosis necrotizing toxin. This is the C-terminal domain secreted by Mycobacterium tuberculosis (Mtb). It induces necrosis of infected cells to evade immune responses. Mtb utilizes the protein CpnT to kill human macrophages by secreting its C-terminal domain (CTD), named tuberculosis necrotizing toxin (TNT) that induces necrosis. It acts as a NAD+ glycohydrolase which hydrolyzes the essential cellular coenzyme NAD+ in the cytosol of infected macrophages resulting in necrotic cell death. CpnT transports its toxic CTD from the cell surface of M. tuberculosis by proteolytic cleavage, where the toxin is cleaved to induce host cell death. Structural analysis determined that the TNT core contains only six beta-strands as opposed to seven found in all known NAD+-utilizing toxins, and is significantly smaller, with only two short alpha-helices and two 3/10 helices. Furthermore, the putative NAD+ binding pocket identified Q822, Y765 and R757 as residues possibly involved in NAD+-binding and hydrolysis based on similar positions of catalytic amino acids of ADP-ribosylating toxins. While glutamine 822 residue was detected to be highly conserved among TNT homologs.	5.12656e-28
NZ_LS483380.1\|WP_111692587.1\|1381508_1381688_+\|XRE-family-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.43085e-09
NZ_LS483380.1\|WP_111692586.1\|1376139_1379286_+\|hypothetical-protein	gnl\|CDD\|367432	pfam03272, Mucin_bdg, Putative mucin or carbohydrate-binding module. This family is the putative binding domain for the substrates of enhancin, and other similar metallopeptidases. This is not the enzymically active, peptidase, part of the proteins - see pfam13402.	1.66016e-15
NZ_LS483380.1\|WP_012515937.1\|1392539_1392944_-\|hypothetical-protein	gnl\|CDD\|317917	pfam15599, Imm63, Immunity protein 63. A predicted immunity protein with an alpha+beta fold and a conserved E+G and ExxY motifs. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, which usually contains toxin domains of the Ntox40, Tox-CdiAC and Tox-ARC families. The protein is also found in poly-immunity loci in polymorphic toxin systems.	0.00883627
NZ_LS483380.1\|WP_012678588.1\|1389190_1389514_-\|hypothetical-protein	gnl\|CDD\|373960	pfam15597, Imm59, Immunity protein 59. A predicted immunity protein with an alpha+beta fold and a conserved [DE]R motif. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, which usually contains toxin domains of the Ntox13 or Ntox40 families. In some proteins this domain is fused to the Imm38, pfam15599 immunity domain.	2.37636e-49
NZ_LS483380.1\|WP_111692584.1\|1370312_1371527_+\|UDP-N-acetylmuramoylpentapeptide-lysine-N(6)-alanyltransferase	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	1.46589e-134
NZ_LS483380.1\|WP_012515923.1\|1373994_1375191_-\|elongation-factor-Tu	gnl\|CDD\|234596	PRK00049, PRK00049, elongation factor Tu; Reviewed.	0
NZ_LS483380.1\|WP_021320962.1\|1383423_1383768_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.7275e-50

>NZ_LS483380.1|WP_111692587.1|1381508_1381688_+|XRE-family-transcriptional-regulator
MHHQRKLAKPSQSQLAELLETNKQTLSMVENGQRKAPIKKLIKLHNIFGVTANELLPKD
>NZ_LS483380.1|WP_012677692.1|1380651_1381122_-|DNA-binding-protein
MAYSKEIIAYLVRSGVAKELARDISQDVLLKMLESDLALPPEKIRAWMYRVAVRKYIDQYRRDKAYLDILQRDFFHQERVVEFDQPNYEPLYTAVNELPEKYRWVLSLYYFQDLSVKEVASLLHWSVSSVKVNLMRGRRCLKEKLKKAGYTYDDFK
>NZ_LS483380.1|WP_042670905.1|1379579_1380668_-|membrane-protein
MTISNDFEAIAKRHKRRLTLKYVVLSAGLALVALVLGYMGLNRLTSINGQYLMAYYNNRIQIAYPNIDVNSFFYNANSQFTGELHSERTKDIDGISVPFEPYRAPYSLVLRRTDSSNEYLVSGDDGRSTYTRGAHYKMPRFFNTKAKITESNYDKPTQDLDFIADMSGQAVEVAITFDKPYLLSDIVKLVPDQLKLNWIWIGTESSYDTSGLFPANLYGFKPNWKANMTYKEQKQLDKKINDILKKDSEADLSKLNAAYDKPVSPMVALQNSYDTFRHYLQEAADNHWINSTYGGANGSHLSEQEDVALFLKNNRNIKTAKFAGIILTGKAEQFASLKTADWIYASNIGQSVTIQPYHQLTK
>NZ_LS483380.1|WP_111692586.1|1376139_1379286_+|hypothetical-protein
MKLKKIIALACVGILTLHQLSPAIVYATTDASDGTAATVNTGDTAAPSAEAKPSQLMTDTQALFTDHSFSKLASNVTQEKIDALKQKATASTEPEKEQILGLLDKAASLLQQFTLQGLGNGVFAQLYFYADGSYTASLVTKKGQPHSYFSTNYATVTILNDKKETVYSKEYVGNVSQVAQTEELELKEGYYLIINKQEPNRFYTNHNDALKQNNTNPYTYVVRDGQLERIDDSNRTLRFLGLGNAEYATLRVDYNASTLTLKTKQTKPHVYFSGSYEKLEVLDTENQVIYTKDFIGTQVLEAKTETIPFKVGYKIRLTGSEHHTRVKFYDDYAVEAPLTLSKNQATLKLLDHSLELMRSKTGSELESEVLTLFKDESTSKLASNVTQEKIDALRQKVTASTEPEKEQILSLLDKAASLLQQFTLQGLGNGVFAQLYFYADGSYTASLVTKKGQPHSYIANNYATLTILNDKKETVYAKEYVGNVSQTAKTESLTLKEGYYLVITKQEPNRFYTNHNDALKQNNTNPYTYMVRNGRLERIDEKNRTLHFLGLGNAEYATLKIDYNASTLTLKTKKTKPHVYFSGTYEKLEVLDLKDKVVYTQDFIGNQVLTAKTETIPFKVGYKIRLTGSEHHTRVKAYDEENKAVSLSLPKNKAEIRITKGGLASVFALEAKATNTLVQAVEKRLTKEKIEDFKKQDDKHKAFIDWLLKDNEAMQLYLGAGYAHSAAQGGMSSYQFKNTYNLTNELEALELWFKIWDKYEASHQGIQLKMAIAVALEFTKPVGAWYNESRKIDPLERFATFAEAEQGNVLFEDFYSLTVEQIRNVVNAKITDEDMKWLRQYVETNKPAMINRNDITKGYSLISYVMTNPETGVSVQSSGFYGPNPTIKEVIKYGGVCGAMSKLSSVLAQAYGVPAFPIGQPGHCAYIYLNADHTYQLGYDVSGWTGCGNYNTTLPYVQIHNVYSLNIDAYNASEYERYKAEAATDKDTKLNHLDAALKAEPLNYKAWNDKLALVASDQTAYQSTLNDMKSALKDYPVIINNLEKDTKQ
>NZ_LS483380.1|WP_012515923.1|1373994_1375191_-|elongation-factor-Tu
MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSVNQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDLLSEYDFPGDDLPVIQGSALKALEGDSKYEDIIMELMDTVDSYIPEPERDTDKPLLLPVEDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIRDEIKKAVVTGVEMFRKQLDEGLAGDNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQFYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGIVSEIEA
>NZ_LS483380.1|WP_014623135.1|1372970_1373729_-|triose-phosphate-isomerase
MSRKPIIAGNWKMNKNPQEAKAFVEAVVSKLPSNDLVDVAVAAPAVDLVTTIEAAKDSVLKVAAQNCYFENSGAYTGETSPKVLAEMGADYVVIGHSERRDYFHETDEDINKKAKTIFANGLTPIICCGESLETYEAGQAVAFVGAQVSAALEGLSAEQVASLVLAYEPIWAIGTGKSATQEDAQSMCKAVRDVVAADFGQEVADKVRVQYGGSVKPENIKEYMACPDVDGALVGGASLEADSFLALLDFVN
>NZ_LS483380.1|WP_111692585.1|1371526_1372762_+|peptidoglycan-branched-peptide-synthesis-protein
MALDIIDKETFGSFCSQMKYKSFIQSIEMAELLQKRGYQTQYLAISDQKDIKIAAILYSIPMTGGLRMEINSGPVVADATYTIAFYKALQDYAKQQGALELVIKPYDTYQTFTSDGHPNDDEKPELIKTLTELNFTHDGLLTGYHNGEGDWHYVKDLSGLTSANVINSFSKKGKALLKKAKTFGIKLHKLNRDELTQFKEITAATSSRRDYTDKSLSYYQDFYDSFGDSCEFMVATLNFDDYLTNLEHSQDKLKQRISKLEADLVKNPRSEKKQNQLRELSSQFDTFQVRIAEAQELIVKYGKKDIPLAGSLFVYTPQEAVYLFSGSYPEFNRFYAPALLQEHVMLRAIEKKISCYNFLGIMGEFDGSDGVLRFKQNFNGYITRKMGTFRYYPKPFKYKAIQAIKTMLGRS
>NZ_LS483380.1|WP_111692584.1|1370312_1371527_+|UDP-N-acetylmuramoylpentapeptide-lysine-N(6)-alanyltransferase
MYTYKIGISAKEHDQFVLSHPQVNLLQSAHWAQVKDNWEHELIGFYQDDKQVAAAACLIKRLPLGMTMIYIPRGPIMDYSDFELVNFVMTSLKAYGKSKRALMIKYDPSLFISQALIGEERKDNDFTLSTIDFLKTIGVEWTGRTKELEQTIQPRFQANIYAKDFKLQSLSKKARQSIRTAQNKGVEIIIGSTELLEDFSALMKKTEERKHISLRDISYYDKLMTTYANQAYITMARLNLPKQKALIQQQLEEALSNQQAFTQHSKPGKVAENQNTIKRLEKELAFLDKEIQAGKSLVPLAATLTLIYGQTSENLYAGMDNDFRQYQAALLTWYHTAEEAFKRGCQWHNLGGVENQLDGGLFQFKARLNPAIEEFAGEFSIPVGPISKVAMIAYNLRKKLRSNP
>NZ_LS483380.1|WP_043026121.1|1369503_1370313_+|sugar-phosphatase
MSIKLVAIDIDGTLLTDDRRVTNDVFDAIQEAKAQGVHIVIATGRPIAGVISLLEQLQLNQKGDHVITFNGGLIQDTATGEEVVKELMTYDDYLDIEYLSRRLGVHMHAITTEGIYTANRNIGKYTVREARLVDMPVFYRTPEEMADKEIVKMMMIDEPNLLDEAIKQIPQAFYDTYNIVKSTPFYLELTPKTVSKGTAIGHLAKKLGIDMSQTMAIGDAENDRAMLEAVANPVVMENGAPELKKLAKYITKSNNDSGVAHAIRKWVLN
>NZ_LS483380.1|WP_021320955.1|1367977_1369279_+|HD-domain-containing-protein
MNEKVFRDPVHNYIHVNHQLIYELINTKEFQRLRRIKQVPTTAFTFHGAEHSRFSHCLGVYEIARRVTEIFEEKYADLWHKEESLVTMTAALLHDIGHGAYSHTFETLFDTDHEAVTQDIITSPETEINAILTRYSPDFPDKVASVINHTYPNKQVVQLISSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVKDGIAFDLSGMHAVEDYIVSRFQMYMQVYFHPASRAVELILQNLLKRAKALYPSQQDYFQKTAPGLIPFFEKSFTLADYLCLDDGVLNTYFQQWITSEDHILSDLSSRFINRKILKSVTFDQESQQDLERLRKLVEAVGFDPDYYTGIHVNFDLPYDIYRPELENPRTQIEMIQKDGSRAELSQLSAIVKALTGTSYGDRRFYFPKEMLELDDLFTSDKEAFISYISNGHFHFNN
>NZ_LS483380.1|WP_111692588.1|1382756_1383431_-|type-II-A-CRISPR-associated-protein-Csn2
MINFSLLDEPLKLEQMTILTVKDVRVFSSLIRNFYQYGESGDLKLFDHRLKGLKETELMIITDILEYDINSPAILKMVHADLEECFNEQPEVKSMLEKLAATITELIVFECLENELDLEYDKITILELIKALGVKVETQSDTIFEKCLEILQVFKYLTKKKLLVFVNSGSYFTREEFEQLKEYVELSNQTVLFLEPRPLYDFPQYILDEDYFLVTQNKLEGIEH
>NZ_LS483380.1|WP_021320962.1|1383423_1383768_-|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPVDTVEERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNNTANNAMIRRLREQNPQKGNITLLTVTEKQFARMIYLHGEKNASIANTDKRLVFLGEAYSGDD
>NZ_LS483380.1|WP_012515930.1|1383764_1384634_-|type-II-CRISPR-associated-endonuclease-Cas1
MAGWRTVVVNTHSKLSYKNNHFIFKDAYKTELIHLSEIDILLLETTDIVLSTMLIKRLVDNNSLVIFCDDKRLPTAMLMPYYARHDSSLQLSRQMAWSEELKADVWTQIIAQKMLNQSCYLGQCSYFEKSQAIMNLYHDLKSFDPSNREGHSARIYFNALFGNQFSREQDCDINAGLDYGYTLLLSIFAREVVICGCMTQFGLKHSNQFNQFNFASDLMEPFRPIIDRIVYDNRHKTFVQIKRQLLSIFSETYPYNGKEMYLSNIVSDYTKKVIKALNNEGEGVPEFRI
>NZ_LS483380.1|WP_111692589.1|1384633_1388680_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKKPYTIALDIGTNSVGWVVVTDDYRVPTKKMKVLGNTERKTIKKNLIGALLFDSSDTAEGTRLKRTARRRYTRRKNRLRYLKEIFTEEMAKVDDGFFQRLEDSFYVLEDKEGDKHPIFANLADEVAYHKKYPTIYHLRKELVDNPQKADLRLIYLAVAHIIKFRGHFLIEGTLSSKNNNLQKSFDHLVDTYNLLFEEQRLLTEGINAKELLSAALSKSKRLENLISLIPGQKKTGIFGNIIALSLGLTPNFKANFGLSKDVKLQLAKDTYADDLDSLLAQIGDQYADLFLAAKNLSDAILLSDILTESDEITSAPLSASMVKRYREHHKDLVTLKTLIKDQLPEKYQKIFLDKTKNGYAGYIEGQVSQEEFYKYLKPILARLDGSEPLLLKIDREDFLRKQRTFDNGSIPHQIHLEELNAILRSQEVFYPFLKDNRKKIESLLTFRIPYYVGPLARGHSRFAWVKRKFDGAIRPWNFEEIVDEEASAQIFIEKMTKNDLYLPNEKVLPKHSLLYETFTVYNELTKVKYATEGMTRPQFLSADQKQAIVDLLFKTNRKVTVKQLKENYFKKIECWDSVEITGVEDSFNASLGTYHDLLKIIQDKDFLDNPDNQKIIEDIILTLTLFEDKKMISKRLDQYAHLFDKVVLNKLERHHYTGWGRLSGKLINGIRDKQSGKTILDFLKADGFANRNFMQLIHDSELSFIDEIAKAQVIGKTEYSKDLVGNLAGSPAIKKGISQTIKIVDELVKIMGYLPQQIVIEMARENQTTAQGIKNARQRMRKLEETAKKLGSNILKEHPVDNSQLQNDKRYLYYLQNGKDMYTGDDLDIDYLSSYDIDHIIPQSFIKNNSIDNKVLTSQGANRGKLDNVPSEAIVRKMKGYWQSLLRAGAISKQKFDNLTKAERGGLTQVDKAGFIQRQLVETRQITKHVAQILDSRFNTEFDDHNKRIRKVHIITLKSKLVSDFRKEFGLYKIRDINHYHHAHDAYLNAVVAKAILGKYPQLAPEFVYGDYPKYNSFKERQKATQKMLFYSNILKFFKDQESLHVNSDGEEIWNANKHLPIIKNVLSIPQVNIVKKTEVQTGGFYKESILSKGNSDKLIPRKNNWDTRKYGGFDSPTVAYSVLVIAKMEKGKAKVLKPVKEMVGITIMERTAFEENPVVFLEARGYREIQEHLIIKLPKYSLFELENGRRRLLASASELQKGNELFLSVDYMTFLYLAAHYHELTGSSEDVLRKKYFVERHLHYFDDIIQMINDFAERHILASSNLEKINHTYHNNSDLPVNERAENIINVFTFVALGAPAAFKFFDATIDRKRYTSTKEVLNATLIHQSVTGLYETRIDLSQLGEN
>NZ_LS483380.1|WP_012678588.1|1389190_1389514_-|hypothetical-protein
MKNLDHQKAELLEAIHQLGYDSLRYSIFSKERPGEWEVVIEYDDTSGVYLVYGTMDRSSYHGKTAYRKFNAAKEGFMTFLEDIVMINKYYVEEGMPVNYDSPLWSNN
>NZ_LS483380.1|WP_111692590.1|1390206_1390953_-|hypothetical-protein
MKTRDKLNTLENYQKVIMFHQCVIESDLEKIEDLLRDERNGIQKSKIDNQQVIHNTKRWMARDLFKIFKATYSAGYPISEVKKAFLDYLDVKCQVLDGQVAYLNDLDIISIAILLDIDTETIAPFIDNIEQVGYDDFLIDFLIRWYRPEWKQHDDISFKRPYGHAQKIIQAPDKEQALGFLRNYIFSKWYAGSNDAPWYNSHKAKNPVFHVGYWSFESGAMAKILELDDSSLKDQQYYPYDLVHWKNV
>NZ_LS483380.1|WP_111692591.1|1391927_1392350_-|hypothetical-protein
MARSQLEWEDVSQYEEVKGYGQRVWKHQGKYYFVAEESGIAVQRVVYELSYDLFELLESGECSLGDVHSKLQDSNWPPTEEEKKQSHRKFVIDTPTALIADPTSVSLFSEEELSRLVPIAEQQWIDWKGKLPDDYISPLK
>NZ_LS483380.1|WP_012515937.1|1392539_1392944_-|hypothetical-protein
MKELKEELMKLLLKIGVTSLNESVLFEEKRPRVYFPEGQTVFLENNIYYVIGVEHGKVNSERTFGEKEDVLYFLLESYVDTIAGKYAWEKVSGDFEQYGKLLPEEQIRVFSMIAPKYGQRRKQELEAQQESDDV
>NZ_LS483380.1|WP_111692592.1|1392952_1394128_-|hypothetical-protein
MDLALSLVTIAVGVAAIVMTAGAATPLVVGAFVVGSGAVAYGASNLYEAGHNIYVGSVGDGLTVATNPLRDTLFMGNDRLYHQIGGLFTTASAALIPIGQTKSIAKGLTEFTIGEVGGFIGGQASYHGTKLLGGSEQDAQRATLVGNILGGIAASSAARRFSLNEPIAARVTKPTYNHQQLLKNLENSRLARESSRFKNYVAREKFTTTLAGMSPEDSQRYIQWHKYAKAGLSPVDRAKFQDWKFTPDIDLYLSNKHIYDNPDYFNQLDGSVIYPGTPESALGRIDGSVHNQGFLNGEYVDDIIDPGTLVDRYGNNNTGRYFSPAGASFGERALPPYMEKMPKKTYITIKPIPNKKGPVAPWFDQPGMGTQYFTDMEGGYLEKYGYLVEID
>NZ_LS483380.1|WP_111692593.1|1394742_1395522_-|hypothetical-protein
MNEPIAAKVTKPTYNRQQLLKNLENNRLARESSRFKNYVAREKFTTTLAGMSLEDSQRYIQWNKYAKAGFSPSDRVRVLEISEKAPKIKLKSRKNRQKFFKKIEATDKEVTRRPDPSSYLAPEYIEAHRHLFDNGAIKIQKFTPQEGGFNNGAIGNPKDHVVFVMPKDVGETLIDVSKGEPRILEDLLGLHLGDLGDSPVAIDIPKESIRNLRIPSGNEGSAFEGYWKPGGRTYPGNMPEAVIDEVPWGDYTIRPLGGN

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LS483380_1	1.1\|566407\|35\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566407-566441	35	MK448862	Streptococcus phage Javan178, complete genome	35036-35070	0	1.0
NZ_LS483380_1	1.4\|566606\|36\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566606-566641	36	MK448862	Streptococcus phage Javan178, complete genome	13715-13750	0	1.0
NZ_LS483380_1	1.6\|566740\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566740-566773	34	NC_009819	Streptococcus phage P9, complete genome	35051-35084	0	1.0
NZ_LS483380_1	1.7\|566806\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566806-566839	34	MK448862	Streptococcus phage Javan178, complete genome	2852-2885	0	1.0
NZ_LS483380_1	1.7\|566806\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566806-566839	34	MK448865	Streptococcus phage Javan182, complete genome	2024-2057	0	1.0
NZ_LS483380_1	1.9\|566938\|36\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566938-566973	36	MK448701	Streptococcus phage Javan197, complete genome	32924-32959	0	1.0
NZ_LS483380_1	1.9\|566938\|36\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566938-566973	36	MK448865	Streptococcus phage Javan182, complete genome	29166-29201	0	1.0
NZ_LS483380_1	1.9\|566938\|36\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566938-566973	36	MK448869	Streptococcus phage Javan190, complete genome	33178-33213	0	1.0
NZ_LS483380_1	1.9\|566938\|36\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566938-566973	36	MK448870	Streptococcus phage Javan192, complete genome	33178-33213	0	1.0
NZ_LS483380_1	1.10\|567006\|33\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567006-567038	33	MK448944	Streptococcus phage Javan452, complete genome	21518-21550	0	1.0
NZ_LS483380_1	1.10\|567006\|33\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567006-567038	33	MK448864	Streptococcus phage Javan180, complete genome	9943-9975	0	1.0
NZ_LS483380_1	1.10\|567006\|33\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567006-567038	33	MK448854	Streptococcus phage Javan146, complete genome	22523-22555	0	1.0
NZ_LS483380_1	1.10\|567006\|33\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567006-567038	33	MK448673	Streptococcus phage Javan119, complete genome	23036-23068	0	1.0
NZ_LS483380_1	1.12\|567138\|35\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567138-567172	35	MK448862	Streptococcus phage Javan178, complete genome	28565-28599	0	1.0
NZ_LS483380_1	1.12\|567138\|35\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567138-567172	35	MK448694	Streptococcus phage Javan179, complete genome	31049-31083	0	1.0
NZ_LS483380_1	1.14\|567270\|35\|NZ_LS483380\|CRISPRCasFinder,CRT	567270-567304	35	MK448854	Streptococcus phage Javan146, complete genome	14632-14666	0	1.0
NZ_LS483380_1	1.14\|567270\|35\|NZ_LS483380\|CRISPRCasFinder,CRT	567270-567304	35	MK448698	Streptococcus phage Javan187, complete genome	9038-9072	0	1.0
NZ_LS483380_3	3.6\|1382416\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382416-1382445	30	MH853357	Streptococcus phage LF3, partial genome	6174-6203	0	1.0
NZ_LS483380_1	1.6\|566740\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566740-566773	34	MK448694	Streptococcus phage Javan179, complete genome	36012-36045	1	0.971
NZ_LS483380_1	1.8\|566872\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566872-566905	34	MK448862	Streptococcus phage Javan178, complete genome	33396-33429	1	0.971
NZ_LS483380_1	1.9\|566938\|36\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566938-566973	36	MK448862	Streptococcus phage Javan178, complete genome	34393-34428	1	0.972
NZ_LS483380_1	1.14\|567270\|35\|NZ_LS483380\|CRISPRCasFinder,CRT	567270-567304	35	MK448784	Streptococcus phage Javan505, complete genome	14564-14598	1	0.971
NZ_LS483380_1	1.14\|567270\|35\|NZ_LS483380\|CRISPRCasFinder,CRT	567270-567304	35	MK448947	Streptococcus phage Javan458, complete genome	14564-14598	1	0.971
NZ_LS483380_1	1.14\|567270\|35\|NZ_LS483380\|CRISPRCasFinder,CRT	567270-567304	35	MK448689	Streptococcus phage Javan163, complete genome	14563-14597	1	0.971
NZ_LS483380_1	1.14\|567270\|35\|NZ_LS483380\|CRISPRCasFinder,CRT	567270-567304	35	MK448974	Streptococcus phage Javan524, complete genome	14564-14598	1	0.971
NZ_LS483380_1	1.14\|567270\|35\|NZ_LS483380\|CRISPRCasFinder,CRT	567270-567304	35	MK448789	Streptococcus phage Javan513, complete genome	14563-14597	1	0.971
NZ_LS483380_3	3.6\|1382416\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382416-1382445	30	KY363359	Streptococcus phage Str03, complete genome	6863-6892	1	0.967
NZ_LS483380_3	3.6\|1382416\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382416-1382445	30	MK448731	Streptococcus phage Javan33, complete genome	23258-23287	1	0.967
NZ_LS483380_3	3.6\|1382416\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382416-1382445	30	MK448992	Streptococcus phage Javan6, complete genome	21265-21294	1	0.967
NZ_LS483380_3	3.6\|1382416\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382416-1382445	30	MK448888	Streptococcus phage Javan26, complete genome	21230-21259	1	0.967
NZ_LS483380_3	3.6\|1382416\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382416-1382445	30	MK448863	Streptococcus phage Javan18, complete genome	19477-19506	1	0.967
NZ_LS483380_1	1.1\|566407\|35\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566407-566441	35	MK448865	Streptococcus phage Javan182, complete genome	29809-29843	2	0.943
NZ_LS483380_1	1.1\|566407\|35\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566407-566441	35	MK448864	Streptococcus phage Javan180, complete genome	27706-27740	2	0.943
NZ_LS483380_1	1.11\|567071\|35\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567071-567105	35	MK448859	Streptococcus phage Javan170, complete genome	3801-3835	2	0.943
NZ_LS483380_1	1.11\|567071\|35\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567071-567105	35	MK448676	Streptococcus phage Javan131, complete genome	3797-3831	2	0.943
NZ_LS483380_1	1.11\|567071\|35\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567071-567105	35	MK448688	Streptococcus phage Javan161, complete genome	3798-3832	2	0.943
NZ_LS483380_1	1.16\|567403\|33\|NZ_LS483380\|CRISPRCasFinder,CRT	567403-567435	33	MK448701	Streptococcus phage Javan197, complete genome	9635-9667	2	0.939
NZ_LS483380_1	1.16\|567403\|33\|NZ_LS483380\|CRISPRCasFinder,CRT	567403-567435	33	MK448865	Streptococcus phage Javan182, complete genome	5265-5297	2	0.939
NZ_LS483380_1	1.16\|567403\|33\|NZ_LS483380\|CRISPRCasFinder,CRT	567403-567435	33	MK448869	Streptococcus phage Javan190, complete genome	9635-9667	2	0.939
NZ_LS483380_1	1.16\|567403\|33\|NZ_LS483380\|CRISPRCasFinder,CRT	567403-567435	33	MK448870	Streptococcus phage Javan192, complete genome	9635-9667	2	0.939
NZ_LS483380_1	1.20\|567405\|31\|NZ_LS483380\|PILER-CR	567405-567435	31	MK448701	Streptococcus phage Javan197, complete genome	9635-9665	2	0.935
NZ_LS483380_1	1.20\|567405\|31\|NZ_LS483380\|PILER-CR	567405-567435	31	MK448865	Streptococcus phage Javan182, complete genome	5265-5295	2	0.935
NZ_LS483380_1	1.20\|567405\|31\|NZ_LS483380\|PILER-CR	567405-567435	31	MK448869	Streptococcus phage Javan190, complete genome	9635-9665	2	0.935
NZ_LS483380_1	1.20\|567405\|31\|NZ_LS483380\|PILER-CR	567405-567435	31	MK448870	Streptococcus phage Javan192, complete genome	9635-9665	2	0.935
NZ_LS483380_1	1.6\|566740\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566740-566773	34	MK448864	Streptococcus phage Javan180, complete genome	26007-26040	3	0.912
NZ_LS483380_1	1.8\|566872\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566872-566905	34	MK448864	Streptococcus phage Javan180, complete genome	25965-25998	3	0.912
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448675	Streptococcus phage Javan129, complete genome	12596-12625	4	0.867
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448862	Streptococcus phage Javan178, complete genome	8518-8547	4	0.867
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK449012	Streptococcus phage Javan94, complete genome	9987-10016	4	0.867
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448972	Streptococcus phage Javan520, complete genome	8467-8496	4	0.867
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448763	Streptococcus phage Javan451, complete genome	9660-9689	4	0.867
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448672	Streptococcus phage Javan117, complete genome	8387-8416	4	0.867
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448849	Streptococcus phage Javan128, complete genome	8291-8320	4	0.867
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448850	Streptococcus phage Javan132, complete genome	13116-13145	4	0.867
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448673	Streptococcus phage Javan119, complete genome	11892-11921	4	0.867
NZ_LS483380_3	3.6\|1382416\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382416-1382445	30	KY065482	Streptococcus phage IPP42, complete genome	18363-18392	4	0.867
NZ_LS483380_3	3.6\|1382416\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382416-1382445	30	KY065483	Streptococcus phage IPP43, complete genome	18803-18832	4	0.867
NZ_LS483380_3	3.6\|1382416\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382416-1382445	30	KY065489	Streptococcus phage IPP51, complete genome	18800-18829	4	0.867
NZ_LS483380_3	3.6\|1382416\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382416-1382445	30	KY065484	Streptococcus phage IPP44, complete genome	18520-18549	4	0.867
NZ_LS483380_3	3.6\|1382416\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382416-1382445	30	MK448734	Streptococcus phage Javan347, complete genome	18675-18704	4	0.867
NZ_LS483380_3	3.6\|1382416\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382416-1382445	30	KY065481	Streptococcus phage IPP41, complete genome	18184-18213	4	0.867
NZ_LS483380_3	3.6\|1382416\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382416-1382445	30	NC_027396	Streptococcus phage SpSL1, complete genome	6189-6218	4	0.867
NZ_LS483380_3	3.6\|1382416\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382416-1382445	30	KY065449	Streptococcus phage IPP5, complete genome	19561-19590	4	0.867
NZ_LS483380_3	3.6\|1382416\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382416-1382445	30	NC_030946	Streptococcus phage phiARI0923, complete genome	14670-14699	4	0.867
NZ_LS483380_1	1.10\|567006\|33\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567006-567038	33	HQ698922	Acinetobacter phage ZZ1, complete genome	63529-63561	5	0.848
NZ_LS483380_1	1.10\|567006\|33\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567006-567038	33	MK240351	Acinetobacter phage Henu6, complete genome	122524-122556	5	0.848
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448771	Streptococcus phage Javan481, complete genome	8542-8571	5	0.833
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448973	Streptococcus phage Javan522, complete genome	10447-10476	5	0.833
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK449010	Streptococcus phage Javan90, complete genome	10976-11005	5	0.833
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448775	Streptococcus phage Javan489, complete genome	12431-12460	5	0.833
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448969	Streptococcus phage Javan514, complete genome	11413-11442	5	0.833
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448681	Streptococcus phage Javan141, complete genome	8318-8347	5	0.833
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448794	Streptococcus phage Javan525, complete genome	10626-10655	5	0.833
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448944	Streptococcus phage Javan452, complete genome	12806-12835	5	0.833
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448774	Streptococcus phage Javan487, complete genome	8527-8556	5	0.833
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448778	Streptococcus phage Javan493, complete genome	10462-10491	5	0.833
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448773	Streptococcus phage Javan485, complete genome	11413-11442	5	0.833
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448958	Streptococcus phage Javan486, complete genome	10767-10796	5	0.833
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448777	Streptococcus phage Javan491, complete genome	8758-8787	5	0.833
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448765	Streptococcus phage Javan459, complete genome	10626-10655	5	0.833
NZ_LS483380_3	3.5\|1382350\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382350-1382379	30	MK448833	Streptococcus phage Javan87, complete genome	10976-11005	5	0.833
NZ_LS483380_1	1.10\|567006\|33\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567006-567038	33	NC_049490	Acinetobacter phage vB_AbaP_Berthold, complete genome	66053-66085	6	0.818
NZ_LS483380_1	1.10\|567006\|33\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567006-567038	33	MT741943	Acinetobacter phage Meroveus, complete genome	65731-65763	6	0.818
NZ_LS483380_1	1.10\|567006\|33\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567006-567038	33	MN709128	Acinetobacter phage Berthold, complete genome	66053-66085	6	0.818
NZ_LS483380_1	1.10\|567006\|33\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567006-567038	33	MN732883	Acinetobacter phage Kimel, complete genome	66037-66069	6	0.818
NZ_LS483380_1	1.10\|567006\|33\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567006-567038	33	NC_049511	Acinetobacter phage AM101, complete genome	65859-65891	6	0.818
NZ_LS483380_1	1.10\|567006\|33\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567006-567038	33	MH460829	Acinetobacter phage vB_ApiM_fHyAci03, complete genome	66404-66436	6	0.818
NZ_LS483380_1	1.10\|567006\|33\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567006-567038	33	MN723850	Acinetobacter phage Apostate, complete genome	64750-64782	6	0.818
NZ_LS483380_1	1.10\|567006\|33\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567006-567038	33	NC_049492	Acinetobacter phage vB_AbaP_Kimel, complete genome	66037-66069	6	0.818
NZ_LS483380_1	1.10\|567006\|33\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567006-567038	33	MT409116	Acinetobacter phage Octan, complete genome	64681-64713	6	0.818
NZ_LS483380_1	1.10\|567006\|33\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567006-567038	33	NC_049491	Acinetobacter phage vB_AbaP_Apostate, complete genome	64750-64782	6	0.818
NZ_LS483380_3	3.3\|1382219\|29\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382219-1382247	29	LT598654	Phage NCTB genome assembly, complete genome: monopartite	64348-64376	6	0.793
NZ_LS483380_3	3.4\|1382284\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382284-1382313	30	NZ_KY303941	Enterococcus faecalis strain 3 plasmid pGTC3, complete sequence	75635-75664	6	0.8
NZ_LS483380_1	1.12\|567138\|35\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567138-567172	35	MK448675	Streptococcus phage Javan129, complete genome	33084-33118	7	0.8
NZ_LS483380_1	1.12\|567138\|35\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567138-567172	35	MK448960	Streptococcus phage Javan492, complete genome	30509-30543	7	0.8
NZ_LS483380_1	1.12\|567138\|35\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567138-567172	35	MK448762	Streptococcus phage Javan447, complete genome	30641-30675	7	0.8
NZ_LS483380_1	1.12\|567138\|35\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567138-567172	35	MK448778	Streptococcus phage Javan493, complete genome	31561-31595	7	0.8
NZ_LS483380_1	1.12\|567138\|35\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567138-567172	35	MK448686	Streptococcus phage Javan157, complete genome	31403-31437	7	0.8
NZ_LS483380_1	1.12\|567138\|35\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567138-567172	35	MK448951	Streptococcus phage Javan470, complete genome	30583-30617	7	0.8
NZ_LS483380_1	1.12\|567138\|35\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567138-567172	35	MK448676	Streptococcus phage Javan131, complete genome	35102-35136	7	0.8
NZ_LS483380_1	1.12\|567138\|35\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567138-567172	35	MK448975	Streptococcus phage Javan526, complete genome	32343-32377	7	0.8
NZ_LS483380_1	1.12\|567138\|35\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567138-567172	35	MK448782	Streptococcus phage Javan501, complete genome	34701-34735	7	0.8
NZ_LS483380_3	3.3\|1382219\|29\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382219-1382247	29	MN234173	Arthrobacter phage Sporto, complete genome	35004-35032	7	0.759
NZ_LS483380_3	3.3\|1382219\|29\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382219-1382247	29	NC_021529	Vibrio phage nt-1, complete genome	199602-199630	7	0.759
NZ_LS483380_1	1.5\|566674\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566674-566707	34	NC_011996	Macrococcus caseolyticus JCSC5402 plasmid pMCCL2, complete sequence	76530-76563	8	0.765
NZ_LS483380_1	1.5\|566674\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566674-566707	34	NZ_CP020479	Campylobacter helveticus strain ATCC 51209 plasmid pHELV-1, complete sequence	3035-3068	8	0.765
NZ_LS483380_1	1.7\|566806\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566806-566839	34	AY543070	Bacteriophage T5, complete genome	5347-5380	8	0.765
NZ_LS483380_1	1.7\|566806\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566806-566839	34	AY543070	Bacteriophage T5, complete genome	116878-116911	8	0.765
NZ_LS483380_1	1.7\|566806\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566806-566839	34	AY587007	Bacteriophage T5 strain ATCC 11303-B5, complete genome	5346-5379	8	0.765
NZ_LS483380_1	1.7\|566806\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566806-566839	34	AY587007	Bacteriophage T5 strain ATCC 11303-B5, complete genome	116959-116992	8	0.765
NZ_LS483380_1	1.7\|566806\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566806-566839	34	AY692264	Bacteriophage T5 strain st0 deletion mutant, complete genome	5347-5380	8	0.765
NZ_LS483380_1	1.7\|566806\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566806-566839	34	AY692264	Bacteriophage T5 strain st0 deletion mutant, complete genome	108836-108869	8	0.765
NZ_LS483380_1	1.7\|566806\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566806-566839	34	NC_005859	Enterobacteria phage T5, complete genome	5347-5380	8	0.765
NZ_LS483380_1	1.7\|566806\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566806-566839	34	NC_005859	Enterobacteria phage T5, complete genome	116878-116911	8	0.765
NZ_LS483380_1	1.7\|566806\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566806-566839	34	MN022787	Salmonella virus VSe12, complete genome	5239-5272	8	0.765
NZ_LS483380_3	3.6\|1382416\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382416-1382445	30	NC_019538	Aeromonas phage CC2, complete genome	128884-128913	8	0.733
NZ_LS483380_1	1.6\|566740\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566740-566773	34	MK448755	Streptococcus phage Javan423, complete genome	13333-13366	9	0.735
NZ_LS483380_1	1.6\|566740\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566740-566773	34	MK448756	Streptococcus phage Javan425, complete genome	13333-13366	9	0.735
NZ_LS483380_1	1.10\|567006\|33\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567006-567038	33	MT001829	Salmonella phage SE_PL, complete genome	113197-113229	9	0.727
NZ_LS483380_1	1.10\|567006\|33\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567006-567038	33	MK773491	Salmonella phage 7t3, complete genome	235536-235568	9	0.727
NZ_LS483380_1	1.10\|567006\|33\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	567006-567038	33	MK268344	Salmonella phage Munch, complete genome	172863-172895	9	0.727
NZ_LS483380_1	1.19\|567339\|32\|NZ_LS483380\|PILER-CR	567339-567370	32	MN528768	Lactococcus phage P596, complete genome	12941-12972	9	0.719
NZ_LS483380_1	1.19\|567339\|32\|NZ_LS483380\|PILER-CR	567339-567370	32	MH586731	Salmonella phage Meda, complete genome	78249-78280	9	0.719
NZ_LS483380_3	3.6\|1382416\|30\|NZ_LS483380\|CRISPRCasFinder,CRT,PILER-CR	1382416-1382445	30	CP037991	Bacillus mycoides strain TH26 plasmid unnamed1, complete sequence	402116-402145	9	0.7
NZ_LS483380_1	1.7\|566806\|34\|NZ_LS483380\|PILER-CR,CRISPRCasFinder,CRT	566806-566839	34	NZ_CP051517	Paraburkholderia aromaticivorans strain AR20-38 plasmid unnamed1	34254-34287	10	0.706

1. spacer 1.1|566407|35|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448862 (Streptococcus phage Javan178, complete genome) position: , mismatch: 0, identity: 1.0

tttttgctagggcttccgcgtcccatttttgcaag	CRISPR spacer
tttttgctagggcttccgcgtcccatttttgcaag	Protospacer
***********************************

2. spacer 1.4|566606|36|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448862 (Streptococcus phage Javan178, complete genome) position: , mismatch: 0, identity: 1.0

aggaaccacgctgattgcttgcgagtcaaacggaag	CRISPR spacer
aggaaccacgctgattgcttgcgagtcaaacggaag	Protospacer
************************************

3. spacer 1.6|566740|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to NC_009819 (Streptococcus phage P9, complete genome) position: , mismatch: 0, identity: 1.0

caaaatgttgtcaatcagtacaatttcggcccct	CRISPR spacer
caaaatgttgtcaatcagtacaatttcggcccct	Protospacer
**********************************

4. spacer 1.7|566806|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448862 (Streptococcus phage Javan178, complete genome) position: , mismatch: 0, identity: 1.0

gagttttaaaagtcaacatctttttttcgttttt	CRISPR spacer
gagttttaaaagtcaacatctttttttcgttttt	Protospacer
**********************************

5. spacer 1.7|566806|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448865 (Streptococcus phage Javan182, complete genome) position: , mismatch: 0, identity: 1.0

gagttttaaaagtcaacatctttttttcgttttt	CRISPR spacer
gagttttaaaagtcaacatctttttttcgttttt	Protospacer
**********************************

6. spacer 1.9|566938|36|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448701 (Streptococcus phage Javan197, complete genome) position: , mismatch: 0, identity: 1.0

taggattgattttagctcaaagagcagatagccaac	CRISPR spacer
taggattgattttagctcaaagagcagatagccaac	Protospacer
************************************

7. spacer 1.9|566938|36|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448865 (Streptococcus phage Javan182, complete genome) position: , mismatch: 0, identity: 1.0

taggattgattttagctcaaagagcagatagccaac	CRISPR spacer
taggattgattttagctcaaagagcagatagccaac	Protospacer
************************************

8. spacer 1.9|566938|36|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448869 (Streptococcus phage Javan190, complete genome) position: , mismatch: 0, identity: 1.0

taggattgattttagctcaaagagcagatagccaac	CRISPR spacer
taggattgattttagctcaaagagcagatagccaac	Protospacer
************************************

9. spacer 1.9|566938|36|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448870 (Streptococcus phage Javan192, complete genome) position: , mismatch: 0, identity: 1.0

taggattgattttagctcaaagagcagatagccaac	CRISPR spacer
taggattgattttagctcaaagagcagatagccaac	Protospacer
************************************

10. spacer 1.10|567006|33|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 0, identity: 1.0

ttcatcagtttttacaaaacttgcaacagttat	CRISPR spacer
ttcatcagtttttacaaaacttgcaacagttat	Protospacer
*********************************

11. spacer 1.10|567006|33|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448864 (Streptococcus phage Javan180, complete genome) position: , mismatch: 0, identity: 1.0

ttcatcagtttttacaaaacttgcaacagttat	CRISPR spacer
ttcatcagtttttacaaaacttgcaacagttat	Protospacer
*********************************

12. spacer 1.10|567006|33|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448854 (Streptococcus phage Javan146, complete genome) position: , mismatch: 0, identity: 1.0

ttcatcagtttttacaaaacttgcaacagttat	CRISPR spacer
ttcatcagtttttacaaaacttgcaacagttat	Protospacer
*********************************

13. spacer 1.10|567006|33|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448673 (Streptococcus phage Javan119, complete genome) position: , mismatch: 0, identity: 1.0

ttcatcagtttttacaaaacttgcaacagttat	CRISPR spacer
ttcatcagtttttacaaaacttgcaacagttat	Protospacer
*********************************

14. spacer 1.12|567138|35|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448862 (Streptococcus phage Javan178, complete genome) position: , mismatch: 0, identity: 1.0

atgatgacaaaaaagagccgacagtcgaagaaatc	CRISPR spacer
atgatgacaaaaaagagccgacagtcgaagaaatc	Protospacer
***********************************

15. spacer 1.12|567138|35|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448694 (Streptococcus phage Javan179, complete genome) position: , mismatch: 0, identity: 1.0

atgatgacaaaaaagagccgacagtcgaagaaatc	CRISPR spacer
atgatgacaaaaaagagccgacagtcgaagaaatc	Protospacer
***********************************

16. spacer 1.14|567270|35|NZ_LS483380|CRISPRCasFinder,CRT matches to MK448854 (Streptococcus phage Javan146, complete genome) position: , mismatch: 0, identity: 1.0

caatcgttgaagatcatcatgccaccgtttttagt	CRISPR spacer
caatcgttgaagatcatcatgccaccgtttttagt	Protospacer
***********************************

17. spacer 1.14|567270|35|NZ_LS483380|CRISPRCasFinder,CRT matches to MK448698 (Streptococcus phage Javan187, complete genome) position: , mismatch: 0, identity: 1.0

caatcgttgaagatcatcatgccaccgtttttagt	CRISPR spacer
caatcgttgaagatcatcatgccaccgtttttagt	Protospacer
***********************************

18. spacer 3.6|1382416|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MH853357 (Streptococcus phage LF3, partial genome) position: , mismatch: 0, identity: 1.0

aatcagttgaatctaaaacaacctgacact	CRISPR spacer
aatcagttgaatctaaaacaacctgacact	Protospacer
******************************

19. spacer 1.6|566740|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448694 (Streptococcus phage Javan179, complete genome) position: , mismatch: 1, identity: 0.971

caaaatgttgtcaatcagtacaatttcggcccct	CRISPR spacer
taaaatgttgtcaatcagtacaatttcggcccct	Protospacer
.*********************************

20. spacer 1.8|566872|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448862 (Streptococcus phage Javan178, complete genome) position: , mismatch: 1, identity: 0.971

atcttcagcctcggccaaatactccaaaaaatca	CRISPR spacer
atcttcggcctcggccaaatactccaaaaaatca	Protospacer
******.***************************

21. spacer 1.9|566938|36|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448862 (Streptococcus phage Javan178, complete genome) position: , mismatch: 1, identity: 0.972

taggattgattttagctcaaagagcagatagccaac	CRISPR spacer
taagattgattttagctcaaagagcagatagccaac	Protospacer
**.*********************************

22. spacer 1.14|567270|35|NZ_LS483380|CRISPRCasFinder,CRT matches to MK448784 (Streptococcus phage Javan505, complete genome) position: , mismatch: 1, identity: 0.971

caatcgttgaagatcatcatgccaccgtttttagt	CRISPR spacer
caatcgttgaagattatcatgccaccgtttttagt	Protospacer
**************.********************

23. spacer 1.14|567270|35|NZ_LS483380|CRISPRCasFinder,CRT matches to MK448947 (Streptococcus phage Javan458, complete genome) position: , mismatch: 1, identity: 0.971

caatcgttgaagatcatcatgccaccgtttttagt	CRISPR spacer
caatcgttgaagattatcatgccaccgtttttagt	Protospacer
**************.********************

24. spacer 1.14|567270|35|NZ_LS483380|CRISPRCasFinder,CRT matches to MK448689 (Streptococcus phage Javan163, complete genome) position: , mismatch: 1, identity: 0.971

caatcgttgaagatcatcatgccaccgtttttagt	CRISPR spacer
caatcgttgaagattatcatgccaccgtttttagt	Protospacer
**************.********************

25. spacer 1.14|567270|35|NZ_LS483380|CRISPRCasFinder,CRT matches to MK448974 (Streptococcus phage Javan524, complete genome) position: , mismatch: 1, identity: 0.971

caatcgttgaagatcatcatgccaccgtttttagt	CRISPR spacer
caatcgttgaagattatcatgccaccgtttttagt	Protospacer
**************.********************

26. spacer 1.14|567270|35|NZ_LS483380|CRISPRCasFinder,CRT matches to MK448789 (Streptococcus phage Javan513, complete genome) position: , mismatch: 1, identity: 0.971

caatcgttgaagatcatcatgccaccgtttttagt	CRISPR spacer
caatcgttgaagattatcatgccaccgtttttagt	Protospacer
**************.********************

27. spacer 3.6|1382416|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to KY363359 (Streptococcus phage Str03, complete genome) position: , mismatch: 1, identity: 0.967

aatcagttgaatctaaaacaacctgacact	CRISPR spacer
aatcaattgaatctaaaacaacctgacact	Protospacer
*****.************************

28. spacer 3.6|1382416|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448731 (Streptococcus phage Javan33, complete genome) position: , mismatch: 1, identity: 0.967

aatcagttgaatctaaaacaacctgacact	CRISPR spacer
aatcaattgaatctaaaacaacctgacact	Protospacer
*****.************************

29. spacer 3.6|1382416|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448992 (Streptococcus phage Javan6, complete genome) position: , mismatch: 1, identity: 0.967

aatcagttgaatctaaaacaacctgacact	CRISPR spacer
aatcaattgaatctaaaacaacctgacact	Protospacer
*****.************************

30. spacer 3.6|1382416|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448888 (Streptococcus phage Javan26, complete genome) position: , mismatch: 1, identity: 0.967

aatcagttgaatctaaaacaacctgacact	CRISPR spacer
aatcaattgaatctaaaacaacctgacact	Protospacer
*****.************************

31. spacer 3.6|1382416|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448863 (Streptococcus phage Javan18, complete genome) position: , mismatch: 1, identity: 0.967

aatcagttgaatctaaaacaacctgacact	CRISPR spacer
aatcaattgaatctaaaacaacctgacact	Protospacer
*****.************************

32. spacer 1.1|566407|35|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448865 (Streptococcus phage Javan182, complete genome) position: , mismatch: 2, identity: 0.943

tttttgctagggcttccgcgtcccatttttgcaag	CRISPR spacer
tttttgctagggcttccgcgtcccatttttgtagg	Protospacer
*******************************.*.*

33. spacer 1.1|566407|35|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448864 (Streptococcus phage Javan180, complete genome) position: , mismatch: 2, identity: 0.943

tttttgctagggcttccgcgtcccatttttgcaag	CRISPR spacer
tttttgctagggcttccgcgtcccatttttgtagg	Protospacer
*******************************.*.*

34. spacer 1.11|567071|35|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448859 (Streptococcus phage Javan170, complete genome) position: , mismatch: 2, identity: 0.943

acctctactttataaaaatctgccaactcatttag	CRISPR spacer
acctctacttcataaaaatccgccaactcatttag	Protospacer
**********.*********.**************

35. spacer 1.11|567071|35|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448676 (Streptococcus phage Javan131, complete genome) position: , mismatch: 2, identity: 0.943

acctctactttataaaaatctgccaactcatttag	CRISPR spacer
acttctacttcataaaaatctgccaactcatttag	Protospacer
**.*******.************************

36. spacer 1.11|567071|35|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448688 (Streptococcus phage Javan161, complete genome) position: , mismatch: 2, identity: 0.943

acctctactttataaaaatctgccaactcatttag	CRISPR spacer
acctctacttcataaaaatccgccaactcatttag	Protospacer
**********.*********.**************

37. spacer 1.16|567403|33|NZ_LS483380|CRISPRCasFinder,CRT matches to MK448701 (Streptococcus phage Javan197, complete genome) position: , mismatch: 2, identity: 0.939

ctaagtcctctttgtgacacatcgggcacactg	CRISPR spacer
ctaagtcctctttgtgacacatcggacatactg	Protospacer
*************************.**.****

38. spacer 1.16|567403|33|NZ_LS483380|CRISPRCasFinder,CRT matches to MK448865 (Streptococcus phage Javan182, complete genome) position: , mismatch: 2, identity: 0.939

ctaagtcctctttgtgacacatcgggcacactg	CRISPR spacer
ctaagtcctctttgtgacacatcggacatactg	Protospacer
*************************.**.****

39. spacer 1.16|567403|33|NZ_LS483380|CRISPRCasFinder,CRT matches to MK448869 (Streptococcus phage Javan190, complete genome) position: , mismatch: 2, identity: 0.939

ctaagtcctctttgtgacacatcgggcacactg	CRISPR spacer
ctaagtcctctttgtgacacatcggacatactg	Protospacer
*************************.**.****

40. spacer 1.16|567403|33|NZ_LS483380|CRISPRCasFinder,CRT matches to MK448870 (Streptococcus phage Javan192, complete genome) position: , mismatch: 2, identity: 0.939

ctaagtcctctttgtgacacatcgggcacactg	CRISPR spacer
ctaagtcctctttgtgacacatcggacatactg	Protospacer
*************************.**.****

41. spacer 1.20|567405|31|NZ_LS483380|PILER-CR matches to MK448701 (Streptococcus phage Javan197, complete genome) position: , mismatch: 2, identity: 0.935

aagtcctctttgtgacacatcgggcacactg	CRISPR spacer
aagtcctctttgtgacacatcggacatactg	Protospacer
***********************.**.****

42. spacer 1.20|567405|31|NZ_LS483380|PILER-CR matches to MK448865 (Streptococcus phage Javan182, complete genome) position: , mismatch: 2, identity: 0.935

aagtcctctttgtgacacatcgggcacactg	CRISPR spacer
aagtcctctttgtgacacatcggacatactg	Protospacer
***********************.**.****

43. spacer 1.20|567405|31|NZ_LS483380|PILER-CR matches to MK448869 (Streptococcus phage Javan190, complete genome) position: , mismatch: 2, identity: 0.935

aagtcctctttgtgacacatcgggcacactg	CRISPR spacer
aagtcctctttgtgacacatcggacatactg	Protospacer
***********************.**.****

44. spacer 1.20|567405|31|NZ_LS483380|PILER-CR matches to MK448870 (Streptococcus phage Javan192, complete genome) position: , mismatch: 2, identity: 0.935

aagtcctctttgtgacacatcgggcacactg	CRISPR spacer
aagtcctctttgtgacacatcggacatactg	Protospacer
***********************.**.****

45. spacer 1.6|566740|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448864 (Streptococcus phage Javan180, complete genome) position: , mismatch: 3, identity: 0.912

caaaatgttgtcaatcagtacaatttcggcccct	CRISPR spacer
caaaatgctgtcaatcagtacaatttcggccgcc	Protospacer
*******.*********************** *.

46. spacer 1.8|566872|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448864 (Streptococcus phage Javan180, complete genome) position: , mismatch: 3, identity: 0.912

atcttcagcctcggccaaatactccaaaaaatca	CRISPR spacer
atcttcggcctcggccaaatactccaaaaagtcg	Protospacer
******.***********************.**.

47. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448675 (Streptococcus phage Javan129, complete genome) position: , mismatch: 4, identity: 0.867

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatggattggagacacatga	Protospacer
***...*.**********************

48. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448862 (Streptococcus phage Javan178, complete genome) position: , mismatch: 4, identity: 0.867

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatggattggagacacatga	Protospacer
***...*.**********************

49. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK449012 (Streptococcus phage Javan94, complete genome) position: , mismatch: 4, identity: 0.867

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatggattggagacacatga	Protospacer
***...*.**********************

50. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 4, identity: 0.867

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatggattggagacacatga	Protospacer
***...*.**********************

51. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 4, identity: 0.867

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatggattggagacacatga	Protospacer
***...*.**********************

52. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448672 (Streptococcus phage Javan117, complete genome) position: , mismatch: 4, identity: 0.867

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatggattggagacacatga	Protospacer
***...*.**********************

53. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448849 (Streptococcus phage Javan128, complete genome) position: , mismatch: 4, identity: 0.867

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatggattggagacacatga	Protospacer
***...*.**********************

54. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448850 (Streptococcus phage Javan132, complete genome) position: , mismatch: 4, identity: 0.867

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatggattggagacacatga	Protospacer
***...*.**********************

55. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448673 (Streptococcus phage Javan119, complete genome) position: , mismatch: 4, identity: 0.867

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatggattggagacacatga	Protospacer
***...*.**********************

56. spacer 3.6|1382416|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to KY065482 (Streptococcus phage IPP42, complete genome) position: , mismatch: 4, identity: 0.867

aatcagttgaatctaaaacaacctgacact	CRISPR spacer
agtcagttgaatctaaaacagcctgataca	Protospacer
*.******************.*****.**

57. spacer 3.6|1382416|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to KY065483 (Streptococcus phage IPP43, complete genome) position: , mismatch: 4, identity: 0.867

aatcagttgaatctaaaacaacctgacact	CRISPR spacer
agtcagttgaatctaaaacagcctgataca	Protospacer
*.******************.*****.**

58. spacer 3.6|1382416|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to KY065489 (Streptococcus phage IPP51, complete genome) position: , mismatch: 4, identity: 0.867

aatcagttgaatctaaaacaacctgacact	CRISPR spacer
agtcagttgaatctaaaacagcctgataca	Protospacer
*.******************.*****.**

59. spacer 3.6|1382416|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to KY065484 (Streptococcus phage IPP44, complete genome) position: , mismatch: 4, identity: 0.867

aatcagttgaatctaaaacaacctgacact	CRISPR spacer
agtcagttgaatctaaaacagcctgataca	Protospacer
*.******************.*****.**

60. spacer 3.6|1382416|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448734 (Streptococcus phage Javan347, complete genome) position: , mismatch: 4, identity: 0.867

aatcagttgaatctaaaacaacctgacact	CRISPR spacer
agtcagttgaatctaaaacagcctgataca	Protospacer
*.******************.*****.**

61. spacer 3.6|1382416|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to KY065481 (Streptococcus phage IPP41, complete genome) position: , mismatch: 4, identity: 0.867

aatcagttgaatctaaaacaacctgacact	CRISPR spacer
agtcagttgaatctaaaacagcctgataca	Protospacer
*.******************.*****.**

62. spacer 3.6|1382416|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to NC_027396 (Streptococcus phage SpSL1, complete genome) position: , mismatch: 4, identity: 0.867

aatcagttgaatctaaaacaacctgacact	CRISPR spacer
agtcagttgaatctaaaacagcctgataca	Protospacer
*.******************.*****.**

63. spacer 3.6|1382416|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to KY065449 (Streptococcus phage IPP5, complete genome) position: , mismatch: 4, identity: 0.867

aatcagttgaatctaaaacaacctgacact	CRISPR spacer
agtcagttgaatctaaaacagcctgataca	Protospacer
*.******************.*****.**

64. spacer 3.6|1382416|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to NC_030946 (Streptococcus phage phiARI0923, complete genome) position: , mismatch: 4, identity: 0.867

aatcagttgaatctaaaacaacctgacact	CRISPR spacer
agtcagttgaatctaaaacagcctgataca	Protospacer
*.******************.*****.**

65. spacer 1.10|567006|33|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to HQ698922 (Acinetobacter phage ZZ1, complete genome) position: , mismatch: 5, identity: 0.848

ttcatcagtttttacaaaacttgcaacagttat	CRISPR spacer
ttcatcagttttaacaaaacttgcaagatataa	Protospacer
************ ************* *  **

66. spacer 1.10|567006|33|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK240351 (Acinetobacter phage Henu6, complete genome) position: , mismatch: 5, identity: 0.848

ttcatcagtttttacaaaacttgcaacagttat	CRISPR spacer
ttcatcagttttaacaaaacttgcaagatataa	Protospacer
************ ************* *  **

67. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 5, identity: 0.833

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatgaattggagacacatga	Protospacer
***...*.******.***************

68. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 5, identity: 0.833

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatgaattggagacacatga	Protospacer
***...*.******.***************

69. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK449010 (Streptococcus phage Javan90, complete genome) position: , mismatch: 5, identity: 0.833

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatggattggagatacatga	Protospacer
***...*.***************.******

70. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448775 (Streptococcus phage Javan489, complete genome) position: , mismatch: 5, identity: 0.833

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatgaattggagacacatga	Protospacer
***...*.******.***************

71. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 5, identity: 0.833

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatgaattggagacacatga	Protospacer
***...*.******.***************

72. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448681 (Streptococcus phage Javan141, complete genome) position: , mismatch: 5, identity: 0.833

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatggattagagacacatga	Protospacer
***...*.**********.***********

73. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448794 (Streptococcus phage Javan525, complete genome) position: , mismatch: 5, identity: 0.833

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatgaattggagacacatga	Protospacer
***...*.******.***************

74. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 5, identity: 0.833

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatgaattggagacacatga	Protospacer
***...*.******.***************

75. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 5, identity: 0.833

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatgaattggagacacatga	Protospacer
***...*.******.***************

76. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 5, identity: 0.833

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatgaattggagacacatga	Protospacer
***...*.******.***************

77. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 5, identity: 0.833

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatgaattggagacacatga	Protospacer
***...*.******.***************

78. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448958 (Streptococcus phage Javan486, complete genome) position: , mismatch: 5, identity: 0.833

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatgaattggagacacatga	Protospacer
***...*.******.***************

79. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448777 (Streptococcus phage Javan491, complete genome) position: , mismatch: 5, identity: 0.833

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatgaattggagacacatga	Protospacer
***...*.******.***************

80. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448765 (Streptococcus phage Javan459, complete genome) position: , mismatch: 5, identity: 0.833

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatgaattggagacacatga	Protospacer
***...*.******.***************

81. spacer 3.5|1382350|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MK448833 (Streptococcus phage Javan87, complete genome) position: , mismatch: 5, identity: 0.833

aggtcgttttgatggattggagacacatga	CRISPR spacer
aggctatcttgatggattggagatacatga	Protospacer
***...*.***************.******

82. spacer 1.10|567006|33|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to NC_049490 (Acinetobacter phage vB_AbaP_Berthold, complete genome) position: , mismatch: 6, identity: 0.818

ttcatcagtttttacaaaacttgcaacagttat	CRISPR spacer
ttcatcagttttaacaaaacttgctaaatataa	Protospacer
************ *********** * *  **

83. spacer 1.10|567006|33|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MT741943 (Acinetobacter phage Meroveus, complete genome) position: , mismatch: 6, identity: 0.818

ttcatcagtttttacaaaacttgcaacagttat	CRISPR spacer
ttcatcagttttaacaaaacttgctaaatataa	Protospacer
************ *********** * *  **

84. spacer 1.10|567006|33|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MN709128 (Acinetobacter phage Berthold, complete genome) position: , mismatch: 6, identity: 0.818

ttcatcagtttttacaaaacttgcaacagttat	CRISPR spacer
ttcatcagttttaacaaaacttgctaaatataa	Protospacer
************ *********** * *  **

85. spacer 1.10|567006|33|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MN732883 (Acinetobacter phage Kimel, complete genome) position: , mismatch: 6, identity: 0.818

ttcatcagtttttacaaaacttgcaacagttat	CRISPR spacer
ttcatcagttttaacaaaacttgctaaatataa	Protospacer
************ *********** * *  **

86. spacer 1.10|567006|33|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to NC_049511 (Acinetobacter phage AM101, complete genome) position: , mismatch: 6, identity: 0.818

ttcatcagtttttacaaaacttgcaacagttat	CRISPR spacer
ttcatcagttttaacaaaacttgctaaatataa	Protospacer
************ *********** * *  **

87. spacer 1.10|567006|33|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MH460829 (Acinetobacter phage vB_ApiM_fHyAci03, complete genome) position: , mismatch: 6, identity: 0.818

ttcatcagtttttacaaaacttgcaacagttat	CRISPR spacer
ttcatcagttttaacaaaacttgctaaatataa	Protospacer
************ *********** * *  **

88. spacer 1.10|567006|33|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MN723850 (Acinetobacter phage Apostate, complete genome) position: , mismatch: 6, identity: 0.818

ttcatcagtttttacaaaacttgcaacagttat	CRISPR spacer
ttcatcagttttaacaaaacttgctaaatataa	Protospacer
************ *********** * *  **

89. spacer 1.10|567006|33|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to NC_049492 (Acinetobacter phage vB_AbaP_Kimel, complete genome) position: , mismatch: 6, identity: 0.818

ttcatcagtttttacaaaacttgcaacagttat	CRISPR spacer
ttcatcagttttaacaaaacttgctaaatataa	Protospacer
************ *********** * *  **

90. spacer 1.10|567006|33|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MT409116 (Acinetobacter phage Octan, complete genome) position: , mismatch: 6, identity: 0.818

ttcatcagtttttacaaaacttgcaacagttat	CRISPR spacer
ttcatcagttttaacaaaacttgctaaatataa	Protospacer
************ *********** * *  **

91. spacer 1.10|567006|33|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to NC_049491 (Acinetobacter phage vB_AbaP_Apostate, complete genome) position: , mismatch: 6, identity: 0.818

ttcatcagtttttacaaaacttgcaacagttat	CRISPR spacer
ttcatcagttttaacaaaacttgctaaatataa	Protospacer
************ *********** * *  **

92. spacer 3.3|1382219|29|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to LT598654 (Phage NCTB genome assembly, complete genome: monopartite) position: , mismatch: 6, identity: 0.793

tgtcttgcttctgattgaagttcagggca	CRISPR spacer
tatcttgcttctgattaaagttcggagtg	Protospacer
*.**************.******.*.*..

93. spacer 3.4|1382284|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KY303941 (Enterococcus faecalis strain 3 plasmid pGTC3, complete sequence) position: , mismatch: 6, identity: 0.8

ttgtatatggtaatacctttggttgtacgt	CRISPR spacer
gtgagtgtggtaattcgtttggttgtacgt	Protospacer
 ** .*.******* * *************

94. spacer 1.12|567138|35|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448675 (Streptococcus phage Javan129, complete genome) position: , mismatch: 7, identity: 0.8

atgatgacaaaaaagagccgacagtcgaagaaatc	CRISPR spacer
acaaaaataaaaaagagccaacagtcgaagaaatt	Protospacer
*..* .*.***********.**************.

95. spacer 1.12|567138|35|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448960 (Streptococcus phage Javan492, complete genome) position: , mismatch: 7, identity: 0.8

atgatgacaaaaaagagccgacagtcgaagaaatc	CRISPR spacer
acaaaaataaaaaagagccaacagtcgaagaaatt	Protospacer
*..* .*.***********.**************.

96. spacer 1.12|567138|35|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448762 (Streptococcus phage Javan447, complete genome) position: , mismatch: 7, identity: 0.8

atgatgacaaaaaagagccgacagtcgaagaaatc	CRISPR spacer
acaaaaataaaaaagagccaacagtcgaagaaatt	Protospacer
*..* .*.***********.**************.

97. spacer 1.12|567138|35|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 7, identity: 0.8

atgatgacaaaaaagagccgacagtcgaagaaatc	CRISPR spacer
acaaaaataaaaaagagccaacagtcgaagaaatt	Protospacer
*..* .*.***********.**************.

98. spacer 1.12|567138|35|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448686 (Streptococcus phage Javan157, complete genome) position: , mismatch: 7, identity: 0.8

atgatgacaaaaaagagccgacagtcgaagaaatc	CRISPR spacer
acaaaaataaaaaagagccaacagtcgaagaaatt	Protospacer
*..* .*.***********.**************.

99. spacer 1.12|567138|35|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448951 (Streptococcus phage Javan470, complete genome) position: , mismatch: 7, identity: 0.8

atgatgacaaaaaagagccgacagtcgaagaaatc	CRISPR spacer
acaaaaataaaaaagagccaacagtcgaagaaatt	Protospacer
*..* .*.***********.**************.

100. spacer 1.12|567138|35|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448676 (Streptococcus phage Javan131, complete genome) position: , mismatch: 7, identity: 0.8

atgatgacaaaaaagagccgacagtcgaagaaatc	CRISPR spacer
acaaaaataaaaaagagccaacagtcgaagaaatt	Protospacer
*..* .*.***********.**************.

101. spacer 1.12|567138|35|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448975 (Streptococcus phage Javan526, complete genome) position: , mismatch: 7, identity: 0.8

atgatgacaaaaaagagccgacagtcgaagaaatc	CRISPR spacer
acaaaaataaaaaagagccaacagtcgaagaaatt	Protospacer
*..* .*.***********.**************.

102. spacer 1.12|567138|35|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448782 (Streptococcus phage Javan501, complete genome) position: , mismatch: 7, identity: 0.8

atgatgacaaaaaagagccgacagtcgaagaaatc	CRISPR spacer
acaaaaataaaaaagagccaacagtcgaagaaatt	Protospacer
*..* .*.***********.**************.

103. spacer 3.3|1382219|29|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to MN234173 (Arthrobacter phage Sporto, complete genome) position: , mismatch: 7, identity: 0.759

tgtcttgcttctgattgaagttcagggca	CRISPR spacer
tgtcgtgcttctggttgaagttccaaccc	Protospacer
**** ********.********* .. *

104. spacer 3.3|1382219|29|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to NC_021529 (Vibrio phage nt-1, complete genome) position: , mismatch: 7, identity: 0.759

tgtcttgcttctgattgaagttcagggca	CRISPR spacer
tcacttgattctgattgaagttcatgaag	Protospacer
*  **** **************** *. .

105. spacer 1.5|566674|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to NC_011996 (Macrococcus caseolyticus JCSC5402 plasmid pMCCL2, complete sequence) position: , mismatch: 8, identity: 0.765

tatgtttgataaaaagctcgaagaagaggattat	CRISPR spacer
cagcctaaataaaaagctcgaagaagaagataat	Protospacer
.*  .* .*******************.*** **

106. spacer 1.5|566674|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020479 (Campylobacter helveticus strain ATCC 51209 plasmid pHELV-1, complete sequence) position: , mismatch: 8, identity: 0.765

tatgtttgataaaaagctcgaagaagaggattat	CRISPR spacer
tcagcttttaaaaaagcttgaagcagaggattat	Protospacer
*  *.**   ********.**** **********

107. spacer 1.7|566806|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to AY543070 (Bacteriophage T5, complete genome) position: , mismatch: 8, identity: 0.765

gagttttaaaagtcaacatctttttttcgttttt	CRISPR spacer
gatttttaaaagtcaatatcttttccaactattt	Protospacer
** *************.*******..   * ***

108. spacer 1.7|566806|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to AY543070 (Bacteriophage T5, complete genome) position: , mismatch: 8, identity: 0.765

gagttttaaaagtcaacatctttttttcgttttt	CRISPR spacer
gatttttaaaagtcaatatcttttccaactattt	Protospacer
** *************.*******..   * ***

109. spacer 1.7|566806|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to AY587007 (Bacteriophage T5 strain ATCC 11303-B5, complete genome) position: , mismatch: 8, identity: 0.765

gagttttaaaagtcaacatctttttttcgttttt	CRISPR spacer
gatttttaaaagtcaatatcttttccaactattt	Protospacer
** *************.*******..   * ***

110. spacer 1.7|566806|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to AY587007 (Bacteriophage T5 strain ATCC 11303-B5, complete genome) position: , mismatch: 8, identity: 0.765

gagttttaaaagtcaacatctttttttcgttttt	CRISPR spacer
gatttttaaaagtcaatatcttttccaactattt	Protospacer
** *************.*******..   * ***

111. spacer 1.7|566806|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to AY692264 (Bacteriophage T5 strain st0 deletion mutant, complete genome) position: , mismatch: 8, identity: 0.765

gagttttaaaagtcaacatctttttttcgttttt	CRISPR spacer
gatttttaaaagtcaatatcttttccaactattt	Protospacer
** *************.*******..   * ***

112. spacer 1.7|566806|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to AY692264 (Bacteriophage T5 strain st0 deletion mutant, complete genome) position: , mismatch: 8, identity: 0.765

gagttttaaaagtcaacatctttttttcgttttt	CRISPR spacer
gatttttaaaagtcaatatcttttccaactattt	Protospacer
** *************.*******..   * ***

113. spacer 1.7|566806|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to NC_005859 (Enterobacteria phage T5, complete genome) position: , mismatch: 8, identity: 0.765

gagttttaaaagtcaacatctttttttcgttttt	CRISPR spacer
gatttttaaaagtcaatatcttttccaactattt	Protospacer
** *************.*******..   * ***

114. spacer 1.7|566806|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to NC_005859 (Enterobacteria phage T5, complete genome) position: , mismatch: 8, identity: 0.765

gagttttaaaagtcaacatctttttttcgttttt	CRISPR spacer
gatttttaaaagtcaatatcttttccaactattt	Protospacer
** *************.*******..   * ***

115. spacer 1.7|566806|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MN022787 (Salmonella virus VSe12, complete genome) position: , mismatch: 8, identity: 0.765

gagttttaaaagtcaacatctttttttcgttttt	CRISPR spacer
gatttttaaaagtcaatatcttttacaactattt	Protospacer
** *************.******* .   * ***

116. spacer 3.6|1382416|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to NC_019538 (Aeromonas phage CC2, complete genome) position: , mismatch: 8, identity: 0.733

aatcagttgaatctaaaacaacctgacact	CRISPR spacer
aatcagtagaatcgaaaacaaccgttttca	Protospacer
******* ***** *********   . *

117. spacer 1.6|566740|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448755 (Streptococcus phage Javan423, complete genome) position: , mismatch: 9, identity: 0.735

caaaatgttgtcaatcagtacaatttcggcccct	CRISPR spacer
caaaattttgtccatcagtacaataccaattact	Protospacer
****** ***** *********** .*.... **

118. spacer 1.6|566740|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK448756 (Streptococcus phage Javan425, complete genome) position: , mismatch: 9, identity: 0.735

caaaatgttgtcaatcagtacaatttcggcccct	CRISPR spacer
caaaattttgtccatcagtacaataccaattact	Protospacer
****** ***** *********** .*.... **

119. spacer 1.10|567006|33|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MT001829 (Salmonella phage SE_PL, complete genome) position: , mismatch: 9, identity: 0.727

ttcatcagtttttacaaaacttgcaacagttat	CRISPR spacer
taatcctaattttccacaacttgcaacagttat	Protospacer
*   .* . **** ** ****************

120. spacer 1.10|567006|33|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK773491 (Salmonella phage 7t3, complete genome) position: , mismatch: 9, identity: 0.727

ttcatcagtttttacaaaacttgcaacagttat	CRISPR spacer
taatcctaattttccacaacttgcaacagttat	Protospacer
*   .* . **** ** ****************

121. spacer 1.10|567006|33|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to MK268344 (Salmonella phage Munch, complete genome) position: , mismatch: 9, identity: 0.727

ttcatcagtttttacaaaacttgcaacagttat	CRISPR spacer
taatcctaattttccacaacttgcaacagttat	Protospacer
*   .* . **** ** ****************

122. spacer 1.19|567339|32|NZ_LS483380|PILER-CR matches to MN528768 (Lactococcus phage P596, complete genome) position: , mismatch: 9, identity: 0.719

gtttgatgatattatttatcaccttgtctgtt	CRISPR spacer
gtttgatcatattatttatctccccatgtaaa	Protospacer
******* ************ **...* *.

123. spacer 1.19|567339|32|NZ_LS483380|PILER-CR matches to MH586731 (Salmonella phage Meda, complete genome) position: , mismatch: 9, identity: 0.719

gtttgatgatattatttatcaccttgtctgtt	CRISPR spacer
ttgtgatgatgctatttatcaccttgaaaata	Protospacer
 * *******..**************   .*

124. spacer 3.6|1382416|30|NZ_LS483380|CRISPRCasFinder,CRT,PILER-CR matches to CP037991 (Bacillus mycoides strain TH26 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

aatcagttgaatctaaaacaacctgacact	CRISPR spacer
tctcagttgaatataaaacaacttgttgag	Protospacer
  ********** *********.** ..

125. spacer 1.7|566806|34|NZ_LS483380|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP051517 (Paraburkholderia aromaticivorans strain AR20-38 plasmid unnamed1) position: , mismatch: 10, identity: 0.706

gagttttaaaagtcaacatctttttttcgttttt	CRISPR spacer
atagtcgaaaagttgacatctttttttcgttcta	Protospacer
. . *. ******..****************.*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

31853 : 42033

Synechococcus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111692895.1\|31853_35594_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	7.4e-38	27.4
WP_111692069.1\|35712_37170_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.6e-55	33.4
WP_111692070.1\|37226_38249_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	3.9e-58	41.1
WP_043029234.1\|38245_38803_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	7.6e-24	37.6
WP_111692071.1\|38949_40497_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH	Q58MG4	Prochlorococcus_phage	3.6e-71	47.0
WP_111692072.1\|40878_42033_-	amidase	A0A2H4IZY5	uncultured_Caudovirales_phage	2.7e-07	29.6

DBSCAN-SWA_2

1004628 : 1027607

Salicola_phage(25.0%)

transposase,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111692134.1\|1004628_1005747_+\|transposase	ISAs1-like element ISSeq10 family transposase	NA	NA	NA	NA
WP_111692434.1\|1005900_1006989_+	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_012515578.1\|1007088_1007427_+	hypothetical protein	A0A248SK58	Salicola_phage	8.2e-05	33.3
WP_111692435.1\|1007462_1008746_-	PLP-dependent aminotransferase family protein	A0A1X9I5H2	Streptococcus_phage	2.0e-112	50.7
WP_043052129.1\|1008825_1009695_+	pyridoxamine kinase	NA	NA	NA	NA
WP_012679501.1\|1009687_1010233_+	membrane protein	NA	NA	NA	NA
WP_111692134.1\|1010869_1011988_-\|transposase	ISAs1-like element ISSeq10 family transposase	NA	NA	NA	NA
WP_043025803.1\|1012181_1013732_+	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	2.0e-50	27.7
WP_021320752.1\|1014154_1014430_+	hypothetical protein	NA	NA	NA	NA
WP_043025804.1\|1014782_1015688_-	diacylglycerol kinase family lipid kinase	NA	NA	NA	NA
WP_012515586.1\|1015797_1016448_-	hemolysin III family protein	NA	NA	NA	NA
WP_012515587.1\|1016431_1016887_-	DUF1836 domain-containing protein	NA	NA	NA	NA
WP_043030786.1\|1017147_1017903_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_014622843.1\|1017930_1018269_+	cupin domain-containing protein	NA	NA	NA	NA
WP_111692436.1\|1018270_1018576_+	acetate kinase	NA	NA	NA	NA
WP_111692437.1\|1019325_1020063_+	DNA-binding response regulator	NA	NA	NA	NA
WP_042670621.1\|1020432_1020633_+\|bacteriocin	ComC/BlpC family peptide pheromone/bacteriocin	NA	NA	NA	NA
WP_111692438.1\|1020699_1021554_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.9e-26	36.0
WP_111692439.1\|1022974_1023205_+\|bacteriocin	ComC/BlpC family peptide pheromone/bacteriocin	NA	NA	NA	NA
WP_111690111.1\|1023210_1023312_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_111692440.1\|1025591_1027607_+\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA

DBSCAN-SWA_3

1547182 : 1680567

113

Streptococcus_phage(20.0%)

transposase,bacteriocin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111692667.1\|1547182_1548346_+\|transposase	IS30-like element ISSeq6 family transposase	NA	NA	NA	NA
WP_111678281.1\|1548720_1549518_+	LacI family transcriptional regulator	NA	NA	NA	NA
WP_012516056.1\|1549671_1550022_+	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_111692668.1\|1550357_1550855_-	hypothetical protein	NA	NA	NA	NA
WP_111692932.1\|1551187_1553587_-	cell division protein FtsK	S5VNE3	Mycobacterium_phage	5.5e-87	50.6
WP_012516059.1\|1553966_1554773_+	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.9e-20	36.6
WP_037579207.1\|1554928_1555762_-	metal ABC transporter permease	NA	NA	NA	NA
WP_111692669.1\|1555762_1556488_-	metal ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.9e-19	34.0
WP_043031220.1\|1556547_1557480_-	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_012516063.1\|1557625_1558273_+	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_111692670.1\|1558322_1559024_-	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_014623299.1\|1559045_1559294_-	hypothetical protein	NA	NA	NA	NA
WP_012516066.1\|1559293_1559848_-	NUDIX hydrolase	NA	NA	NA	NA
WP_111692671.1\|1559878_1561261_-	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L140	Tupanvirus	1.9e-31	36.9
WP_111692672.1\|1561606_1562581_-	gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_012516071.1\|1563234_1563933_-	3-oxoacyl-ACP reductase	NA	NA	NA	NA
WP_012516072.1\|1563925_1564162_-	DUF2829 domain-containing protein	NA	NA	NA	NA
WP_111692673.1\|1564661_1565336_+	hypothetical protein	NA	NA	NA	NA
WP_111692933.1\|1565548_1566106_-	murein L,D-transpeptidase	NA	NA	NA	NA
WP_111692674.1\|1566248_1568900_-\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	3.0e-150	41.1
WP_111692675.1\|1568912_1569476_-	shikimate kinase	NA	NA	NA	NA
WP_043031237.1\|1569675_1570260_-	N-acetyltransferase	NA	NA	NA	NA
WP_111692676.1\|1570519_1571020_-	DNA-binding protein	NA	NA	NA	NA
WP_043031239.1\|1571041_1571296_-	DUF1912 family protein	NA	NA	NA	NA
WP_012679918.1\|1573401_1574157_+	3-deoxy-7-phosphoheptulonate synthase	NA	NA	NA	NA
WP_111692677.1\|1574215_1575298_+	3-dehydroquinate synthase	NA	NA	NA	NA
WP_012677537.1\|1575627_1576401_-	phosphorylase	F5CA76	Streptococcus_phi-m46.1-like_phage	5.8e-22	39.6
WP_021321039.1\|1576521_1577406_-	shikimate dehydrogenase (NADP+)	NA	NA	NA	NA
WP_111692678.1\|1577556_1580979_-	beta-galactosidase	NA	NA	NA	NA
WP_042671039.1\|1580992_1582477_-	DNA-binding response regulator	NA	NA	NA	NA
WP_042671041.1\|1582476_1584201_-	sensor histidine kinase	NA	NA	NA	NA
WP_111692679.1\|1584190_1584796_-	hypothetical protein	NA	NA	NA	NA
WP_111692680.1\|1585143_1586589_-	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_043052298.1\|1586672_1587599_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_012677529.1\|1587608_1588559_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_111692681.1\|1588770_1589664_+	ROK family protein	NA	NA	NA	NA
WP_111692682.1\|1589651_1591826_+	alpha-mannosidase	NA	NA	NA	NA
WP_111692683.1\|1592072_1593464_-	6-phospho-beta-glucosidase	A0A0B5JD41	Pandoravirus	4.7e-38	26.2
WP_111692684.1\|1593489_1595184_-	hyaluronidase	NA	NA	NA	NA
WP_111692685.1\|1595198_1596257_-	LacI family transcriptional regulator	NA	NA	NA	NA
WP_111692686.1\|1596362_1597676_+	metal-independent alpha-mannosidase	NA	NA	NA	NA
WP_111692687.1\|1597690_1600417_+	alpha-mannosidase	NA	NA	NA	NA
WP_111692688.1\|1600605_1601214_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-19	34.1
WP_111692689.1\|1601210_1603214_-	ABC transporter permease	NA	NA	NA	NA
WP_111692934.1\|1603913_1604117_+	hypothetical protein	NA	NA	NA	NA
WP_111692690.1\|1604208_1604799_-	N-acetyltransferase	NA	NA	NA	NA
WP_012679937.1\|1605048_1605462_-	hypothetical protein	NA	NA	NA	NA
WP_012677518.1\|1605908_1606118_-	hypothetical protein	NA	NA	NA	NA
WP_012516109.1\|1606124_1606328_-\|bacteriocin	bacteriocin BlpN-like	NA	NA	NA	NA
WP_111692691.1\|1606344_1606599_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_111692692.1\|1606752_1607049_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_037579371.1\|1607048_1607267_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_111692935.1\|1607984_1608281_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_111692693.1\|1608287_1608536_-\|bacteriocin	ComC/BlpC family peptide pheromone/bacteriocin	NA	NA	NA	NA
WP_111692694.1\|1608795_1610952_+	peptide ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.8e-42	27.5
WP_111692695.1\|1610962_1612321_+\|bacteriocin	bacteriocin ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_111692696.1\|1612420_1612555_+\|bacteriocin	ComC/BlpC family peptide pheromone/bacteriocin	NA	NA	NA	NA
WP_111692697.1\|1612672_1614007_-	histidine kinase	NA	NA	NA	NA
WP_042671079.1\|1614006_1614756_-	DNA-binding response regulator	NA	NA	NA	NA
WP_012516120.1\|1615382_1615586_-\|bacteriocin	TmhB bacteriocin enhancer peptide	NA	NA	NA	NA
WP_111678353.1\|1615602_1615860_-\|bacteriocin	ThmA bacteriocin	NA	NA	NA	NA
WP_042671083.1\|1616180_1617548_-	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	1.2e-70	33.1
WP_111692698.1\|1617544_1618513_-	DNA-binding protein	NA	NA	NA	NA
WP_111692699.1\|1618576_1619353_+	recombination regulator RecX	NA	NA	NA	NA
WP_012516131.1\|1619585_1620119_+	DUF402 domain-containing protein	NA	NA	NA	NA
WP_111692170.1\|1627222_1628620_+\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_014623350.1\|1628717_1629266_-	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_111692700.1\|1629341_1629923_-	ComF family protein	NA	NA	NA	NA
WP_111692701.1\|1629981_1631304_-	DNA/RNA helicase	A0A1X9I5S6	Streptococcus_phage	2.2e-122	52.3
WP_043031300.1\|1631359_1632001_+	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	4.7e-62	57.9
WP_012679990.1\|1632121_1633048_+	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	3.8e-137	81.0
WP_111692702.1\|1633434_1633797_-	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_111692703.1\|1633796_1635197_-	Cof-type HAD-IIB family hydrolase	A0A1V0S9I2	Catovirus	1.3e-24	42.3
WP_021321066.1\|1635229_1635871_-	DNA-binding response regulator	NA	NA	NA	NA
WP_012516143.1\|1635863_1636868_-	sensor histidine kinase	NA	NA	NA	NA
WP_012679994.1\|1636864_1637557_-	transporter	NA	NA	NA	NA
WP_012516145.1\|1637689_1639585_-	Stk1 family PASTA domain-containing Ser/Thr kinase	A0A1B1IUU3	uncultured_Mediterranean_phage	7.5e-23	36.3
WP_012516146.1\|1639581_1640322_-	Stp1/IreP family PP2C-type Ser/Thr phosphatase	NA	NA	NA	NA
WP_111692936.1\|1640359_1641682_-	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA	NA	NA	NA
WP_043984113.1\|1641671_1642607_-\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	8.9e-09	37.8
WP_111692704.1\|1642673_1645058_-	primosomal protein N'	NA	NA	NA	NA
WP_012516150.1\|1645121_1645439_-	DNA-directed RNA polymerase subunit omega	NA	NA	NA	NA
WP_043039354.1\|1645463_1646090_-	guanylate kinase	K4JYM5	Abalone_herpesvirus	4.7e-22	34.5
WP_043039355.1\|1646253_1647864_-	ribonuclease Y	NA	NA	NA	NA
WP_043039356.1\|1648020_1648506_+	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_111692705.1\|1648650_1650102_-	hypothetical protein	NA	NA	NA	NA
WP_111692706.1\|1650115_1651270_-	class I SAM-dependent RNA methyltransferase	NA	NA	NA	NA
WP_012516157.1\|1651715_1652039_-	cell division regulator GpsB	NA	NA	NA	NA
WP_012516158.1\|1652160_1652676_-	DUF1273 domain-containing protein	NA	NA	NA	NA
WP_012516159.1\|1652751_1653360_+	Holliday junction resolvase RecU	NA	NA	NA	NA
WP_012680007.1\|1653346_1655512_+	penicillin-binding protein	NA	NA	NA	NA
WP_111692707.1\|1655554_1656889_-	aminopeptidase C	NA	NA	NA	NA
WP_037579792.1\|1657575_1658400_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	1.7e-72	57.5
WP_111692708.1\|1658396_1659857_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	7.2e-98	41.6
WP_111692709.1\|1660132_1661527_-	amino acid transporter	NA	NA	NA	NA
WP_043984101.1\|1661647_1662565_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	5.7e-85	50.2
WP_043041027.1\|1662624_1662852_-	DUF4059 family protein	NA	NA	NA	NA
WP_111692710.1\|1662961_1663705_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.8e-28	38.8
WP_042357176.1\|1663704_1664508_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_043041030.1\|1664884_1665712_-	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_111678419.1\|1666219_1666675_+	hypothetical protein	NA	NA	NA	NA
WP_012516173.1\|1667225_1668569_-	ATP-dependent helicase	A0A1B1IS59	uncultured_Mediterranean_phage	2.6e-46	30.5
WP_021321078.1\|1668651_1669659_-	phospho-N-acetylmuramoyl-pentapeptide- transferase	NA	NA	NA	NA
WP_043026446.1\|1669660_1671916_-	PASTA domain-containing protein	NA	NA	NA	NA
WP_012516176.1\|1671919_1672243_-	cell division protein FtsL	NA	NA	NA	NA
WP_012516177.1\|1672246_1673197_-	ribosomal RNA small subunit methyltransferase H	NA	NA	NA	NA
WP_111692711.1\|1673299_1673716_-	hypothetical protein	NA	NA	NA	NA
WP_111692712.1\|1673735_1674986_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.1e-115	56.1
WP_012516180.1\|1674982_1675801_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.2e-38	37.3
WP_111692713.1\|1676412_1677531_+	hypothetical protein	NA	NA	NA	NA
WP_111692714.1\|1677908_1679537_-	ABC transporter permease	NA	NA	NA	NA
WP_014623384.1\|1679541_1680273_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.1e-27	30.0
WP_111692715.1\|1680309_1680567_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LS483380

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection