CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483382	Streptococcus pyogenes strain NCTC13738 chromosome 1	1 crisprs	DinG,csm6,cas3,DEDDh,csa3	0	0	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483382_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483382_1

1108831-1108951

Orphan

Consensus_repeat	Method
CAGCTTCTTCTGATTGTAAAGCGTCTGTTTGATCCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483382_1

>merge|NZ_LS483382|1|1108831-1108951|CRISPRCasFinder
CAGCTTCTTCTGATTGTAAAGCGTCTGTTTGATCCGCCAATGCTTCTAAGGCGTCACTAGCAGCGTTATCCGCTTTAACAACCGCAGCTTCTTCTGATTGTAAAGCGTCTGCTTGATCCGC

>NZ_LS483382|1|1|1108831-1108951|CRISPRCasFinder
CAGCTTCTTCTGATTGTAAAGCGTCTGTTTGATCCGC	CAATGCTTCTAAGGCGTCACTAGCAGCGTTATCCGCTTTAACAACCG
CAGCTTCTTCTGATTGTAAAGCGTCTGCTTGATCCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483382.1\|WP_044555083.1\|1106519_1107803_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|226594
NZ_LS483382.1\|WP_002989306.1\|1103282_1104566_-\|3-phosphoshikimate-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|235037
NZ_LS483382.1\|WP_014407658.1\|1118875_1119685_+\|PrsW-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|225217
NZ_LS483382.1\|WP_002984100.1\|1105643_1106504_-\|methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|180918
NZ_LS483382.1\|WP_011284923.1\|1111035_1112232_-\|methionine-adenosyltransferase	unknown	unknown	gnl\|CDD\|235374
NZ_LS483382.1\|WP_023079396.1\|1118233_1118731_-\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|224867
NZ_LS483382.1\|WP_023079397.1\|1116563_1118234_-\|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl\|CDD\|235505
NZ_LS483382.1\|WP_076634353.1\|1099702_1101091_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|225174
NZ_LS483382.1\|WP_076634354.1\|1102798_1103290_-\|shikimate-kinase	unknown	unknown	gnl\|CDD\|234654
NZ_LS483382.1\|WP_002989295.1\|1109602_1110862_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|183779
NZ_LS483382.1\|WP_002984102.1\|1104676_1105642_-\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
NZ_LS483382.1\|WP_002984060.1\|1120080_1120707_-\|uridine-kinase	unknown	unknown	gnl\|CDD\|235492
NZ_LS483382.1\|WP_076634352.1\|1098900_1099467_-\|nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|350158
NZ_LS483382.1\|WP_002984063.1\|1119737_1120001_-\|DUF1294-domain-containing-protein	unknown	unknown	gnl\|CDD\|225863
NZ_LS483382.1\|WP_011284919.1\|1101139_1102591_-\|LCP-family-protein	unknown	unknown	gnl\|CDD\|224235
NZ_LS483382.1\|WP_002992607.1\|1116265_1116469_-\|DUF3272-domain-containing-protein	unknown	unknown	gnl\|CDD\|314526
NZ_LS483382.1\|WP_002984095.1\|1107811_1108354_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_LS483382.1\|WP_011017924.1\|1115349_1116291_+\|bifunctional-biotin--[acetyl-CoA-carboxylase]-synthetase/biotin-operon-repressor	unknown	unknown	gnl\|CDD\|237010
NZ_LS483382.1\|WP_076634356.1\|1112767_1115146_-\|leucine-rich-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|227223
NZ_LS483382.1\|WP_076634351.1\|1098414_1098816_-\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|224961

Protein	Function_ID	Function_description	E-value
NZ_LS483382.1\|WP_044555083.1\|1106519_1107803_-\|CBS-domain-containing-protein	gnl\|CDD\|226594	COG4109, COG4109, Predicted transcriptional regulator containing CBS domains [Transcription].	0
NZ_LS483382.1\|WP_002989306.1\|1103282_1104566_-\|3-phosphoshikimate-1-carboxyvinyltransferase	gnl\|CDD\|235037	PRK02427, PRK02427, 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional.	0
NZ_LS483382.1\|WP_014407658.1\|1118875_1119685_+\|PrsW-family-intramembrane-metalloprotease	gnl\|CDD\|225217	COG2339, prsW, Membrane proteinase, regulator of anti-sigma factor [Posttranslational modification, protein turnover, chaperones].	1.71282e-58
NZ_LS483382.1\|WP_002984100.1\|1105643_1106504_-\|methionyl-aminopeptidase	gnl\|CDD\|180918	PRK07281, PRK07281, methionyl aminopeptidase.	0
NZ_LS483382.1\|WP_011284923.1\|1111035_1112232_-\|methionine-adenosyltransferase	gnl\|CDD\|235374	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated.	0
NZ_LS483382.1\|WP_023079396.1\|1118233_1118731_-\|GAF-domain-containing-protein	gnl\|CDD\|224867	COG1956, COG1956, GAF domain-containing protein [Signal transduction mechanisms].	6.36689e-82
NZ_LS483382.1\|WP_023079397.1\|1116563_1118234_-\|DNA-polymerase-III-subunit-gamma/tau	gnl\|CDD\|235505	PRK05563, PRK05563, DNA polymerase III subunits gamma and tau; Validated.	0
NZ_LS483382.1\|WP_076634353.1\|1099702_1101091_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	0
NZ_LS483382.1\|WP_076634354.1\|1102798_1103290_-\|shikimate-kinase	gnl\|CDD\|234654	PRK00131, aroK, shikimate kinase; Reviewed.	5.63671e-64
NZ_LS483382.1\|WP_002989295.1\|1109602_1110862_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl\|CDD\|183779	PRK12830, PRK12830, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Reviewed.	0
NZ_LS483382.1\|WP_002984102.1\|1104676_1105642_-\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	8.07812e-56
NZ_LS483382.1\|WP_002984060.1\|1120080_1120707_-\|uridine-kinase	gnl\|CDD\|235492	PRK05480, PRK05480, uridine/cytidine kinase; Provisional.	8.03786e-135
NZ_LS483382.1\|WP_076634352.1\|1098900_1099467_-\|nucleoside-phosphorylase	gnl\|CDD\|350158	cd09007, NP-I_spr0068, uncharacterized subfamily of the nucleoside phosphorylase-I family. This subfamily is composed of uncharacterized members including Streptococcus pneumoniae hypothetical protein spr0068. The nucleoside phosphorylase-I (NP-I) family members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases such as purine nucleoside phosphorylase (PNP, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases such as AMP nucleosidase (AMN, EC 3.2.2.4) and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). Members of the NP-I family display different physiologically relevant quaternary structures: hexameric (trimer-of-dimers arrangement of Shewanella oneidensis MR-1 UP); homotrimeric (human PNP and Escherichia coli PNPII or XapA); hexameric (with some evidence for co-existence of a trimeric form) such as E. coli PNPI (DeoD); or homodimeric such as human and Trypanosoma brucei UP. The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	6.22025e-79
NZ_LS483382.1\|WP_002984063.1\|1119737_1120001_-\|DUF1294-domain-containing-protein	gnl\|CDD\|225863	COG3326, COG3326, Predicted membrane protein [Function unknown].	7.58952e-28
NZ_LS483382.1\|WP_011284919.1\|1101139_1102591_-\|LCP-family-protein	gnl\|CDD\|224235	COG1316, LytR, Transcriptional regulator [Transcription].	4.14317e-64
NZ_LS483382.1\|WP_002992607.1\|1116265_1116469_-\|DUF3272-domain-containing-protein	gnl\|CDD\|314526	pfam11676, DUF3272, Protein of unknown function (DUF3272). This family of proteins with unknown function appears to be restricted to Streptococcus.	1.60094e-22
NZ_LS483382.1\|WP_002984095.1\|1107811_1108354_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	1.44756e-30
NZ_LS483382.1\|WP_011017924.1\|1115349_1116291_+\|bifunctional-biotin--[acetyl-CoA-carboxylase]-synthetase/biotin-operon-repressor	gnl\|CDD\|237010	PRK11886, PRK11886, bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA.	3.03251e-144
NZ_LS483382.1\|WP_076634356.1\|1112767_1115146_-\|leucine-rich-repeat-domain-containing-protein	gnl\|CDD\|227223	COG4886, COG4886, Leucine-rich repeat (LRR) protein [Function unknown].	3.89607e-31
NZ_LS483382.1\|WP_076634351.1\|1098414_1098816_-\|PaaI-family-thioesterase	gnl\|CDD\|224961	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis, transport, and catabolism].	8.40407e-25

>NZ_LS483382.1|WP_002984095.1|1107811_1108354_-|GNAT-family-N-acetyltransferase
MDIWTKLAVFAFFETPKVILRPFRYEDHWDFYSMVNDTKNLYYVFPEQKTKAASDYLLVHSFIKFPLGQWAIEDKATHQVIGSIRIEHYDAKTRCADIGYFLNYAFWGQGIMTEVVIKLVYLSFHEFGLKTLRIITHLENKASQKVAKKAGFQLKTCFKGSDRNTHKICIYKMYQLTNDR
>NZ_LS483382.1|WP_044555083.1|1106519_1107803_-|CBS-domain-containing-protein
MSKHQDILDYLEKLAIGKKVSVRSISNHLKVSDGTAYRAIKEAENRGIVETKPRSGTVRIEKKGRVRIDRLTYSEIARISDSEVLAGHAGLGHEFSRFSIGAMTQQNIRRYLVKGGLLIVGDRETIQLLALENHNAILVTGGFPVSKRVIEMANNQRIPVMVTHYDTFTVATMINHALSNIRIKTDLKTVEQVMIPITDYGYLCEDSSVEEFNTLIKKTRQVRFPVLDYKRKVIGVVSMRDVVDQLPTTKLTKVMSKNPITARPNTSLANISQKMIFEDLNMLPVTDEENNLLGMITRRQAMENLPNHQPNNPYTYSEQILSNLEETVDYYQVVVEPTMIDSAGNMSNGVISEFLKEISIRALTKKHQKNIIIEQMMIYFLHAIQIEDELKIYPKIITENRRSSTIDIEIFVDDQVIAKAIITTKIN
>NZ_LS483382.1|WP_002984100.1|1105643_1106504_-|methionyl-aminopeptidase
MITLKSAREIEAMDRAGDFLAGIHIGLRDIIKPGVDMWEVEAYVRRRCKEDNVLPLQIGVDGHMMDYPYATCCGLNDEVAHAFPRHYILKEGDLLKVDMVLSEPLDKSIVDVAALDFDNVPEMKKWTGSYTGGLADSCWAYAVGTPSDEIKQLMDVTKEAMYRGIEKAVIGNRIGDIGAAVQEYAESFGYGVVRDLVGHGVGPTMHEEPMVPNYGTAGRGLRLKEGMVLTVEPMINTGTWEIDTDIKTGWAHKTLDGGLSCQYEHQFVITKDGPVILTSQGEERTY
>NZ_LS483382.1|WP_002984102.1|1104676_1105642_-|YihY/virulence-factor-BrkB-family-protein
MAEKKWFDKVLSKWQYEPIQVFMRHLQSAEMDLSAIAVAYYLILTAFPLIVIAANIFPYLNIDIADLLRLMKQNLPKDIFRPASAIVENIFSKPSGSVLGVATLTGLWTMSRSLTSLQKAINKAYGASQHRDFFIGHLVGLLTSLIILFLLAFALIFSTFSKAAIQVLDKHYHLSDNITTIFLLLIQPITVLIIFVGLMLLYFLLPNVKIKKIRYILPGTLFTSFVMTFLSNLVGNYVVYNVERMVDIKMFGSVMIFIIMLWFIFLARILILGAIFNATYQEMSLGKLEGRSGDMIAILKKTLGNDSDLSPSQSIEDSHTD
>NZ_LS483382.1|WP_002989306.1|1103282_1104566_-|3-phosphoshikimate-1-carboxyvinyltransferase
MKLRTNAGPLQGTIQVPGDKSISHRAVILGAVAKGETRVKGLLKGEDVLSTIQAFRNLGVRIEEKDDQLVIEGQGFQGLTAPCQTLNMGNSGTSMRLIAGLLAGQPFSVKMIGDESLSKRPMDRIVYPLKQMGVEISGETDRQFPPLQLQGNRNLQPITYTLPISSAQVKSAILLAALQAKGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVGPQQLTAQEITVPGDISSAAFWLVAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQIVYEDMNKKEQVTSIRVVYSHLKGTIISGGLIPRLIDELPIIALLATQAQGTTCIKDAQELRVKETDRIQVVTDTLNSMGANIKATADGMIIKGPTVLYGANTSTYGDHRIGMMTAIAALLVKQGQVHLDKEEAIMTSYPTFFKDLERLCHD
>NZ_LS483382.1|WP_076634354.1|1102798_1103290_-|shikimate-kinase
MTKVLLGFMGVGKTTVSKHLSMHCKDMDAIIEAKIGMSIAAFFEQHGEIAFRTIESQVLKDLLFAKDNSVIVTGGGVVVLQENRQLLRKNHQHNILLVASFETLYQRLKHDKKSQRPLFLKYSKEAFYEFYQQRMVFYEGLSDLVIRVDHRTPEEVANIIEGY
>NZ_LS483382.1|WP_011284919.1|1101139_1102591_-|LCP-family-protein
MTKYPMGGLSHHEELRYFYLLRNLSYLSENEKKEFAFLKSKLEIGRAYAPSKQHYRKSKRQEPYFEDDYYNDYSPNDLLEDDDVNHDSSFVPYGLPIYPKEDRYLNKKTKLTARRPIDTPQPIDEDDAFLTESVARCALPRSQKRKHKKKGCMKWFFNILGLLLMTVLMGLGLMFAKGVFDISTNKANYKPAVSQAFDGQETQDGTNILVLGSDQRVTQGSTDARTDTIMVVNVGNHAKKIKMVSFMRDTLINIPGYSYNDNSYDLKLNSAFNLGEQEDHHGAEYVRRALKHNFDIDIKYYVMVDFETFAEAIDTLFPNGVKIDAKFATVGGVAVDSVEVPDDLRMKNGVVPNQTIEVGEQRMDGRTLLNYARFRKDDEGDFGRTVRQQQVMSAVMSQIKDPTKLFTGSAAIGKIYALTSTNVSFPFVVKNGVSVLGSGKNGVEHVTIPENGDWVDEYDMYGGQALYIDFDKYQKTLAKLGLR
>NZ_LS483382.1|WP_076634353.1|1099702_1101091_-|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MVSPRKGKRIRMLKKNDIIQVAISDLSHEGAGVAKHDGFVFFVDNALPEEVIDMRVLKVNKNSGFGKVEAYHYLSPARNADVNLTYLRTGIADLGHLTYEDQLTFKKKQVQDSLYKIAGISDVTVESTIGMTEPLAYRNKAQVPVRRVNGQLETGFFRKHSHDLIPISDYYIQDKEIDRLINFTRDLLRRFDIKPYDETEQTGLLRNIVVRRGHYSGEMMLVLVTTRPKVFRVDQVIEKIVEAFPAVVSIIQNINDKNTNAIFGKDCKTLYGKDTITDSMLGNNYAISAQSFYQVNTVMAEKLYQTAIAFSDLSKDDIVIDAYSGIGTIGLSFAKTVKAVYGVEVIEAAVRDAQQNAALNGITNAYFVADTAEHAMATWAKDGIKPSVILVDPPRKGLTESFIQASVAMGPQKITYVSCNPATMARDIKRYQELGYKLTKVQPVDLFPQTHHVECVVLLIKE
>NZ_LS483382.1|WP_076634352.1|1098900_1099467_-|nucleoside-phosphorylase
MSYKGQDICLAQVPAAQFMDWLIGYGVKEMISTGTCGVLVPIAENRFLVPVKALRDEGTSYHYVAPSRYIDIDPKMLRLIEKTLLAQGLAYQEVITWSTDGFYRETKEKVAYRQGEGCSVVEMECSALAAVAQLRGILWGQLLFTADTLADVEVYDQRNWGADSFSFALHLCLEVLNTLEKDGKATDF
>NZ_LS483382.1|WP_076634351.1|1098414_1098816_-|PaaI-family-thioesterase
MSDLTQEMTLNVISIFDNYQIELAEKGHLILSTEVTETALNYYGNAHGGYLFTLCDQVGGLVARTTGVESVTLQANANYLKAGYKGDKLMVEGRLVHGGRTTQVVDVTIHNQTGALLTKTSLTMFVTGRRHNG
>NZ_LS483382.1|WP_002989295.1|1109602_1110862_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIYMDTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGTYIALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKADGRGTIIDTIYEKRINHVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITNIEFILRGYASIIAKLTALGADIQLIED
>NZ_LS483382.1|WP_011284923.1|1111035_1112232_-|methionine-adenosyltransferase
MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAETCVYTGSVHVFGEISTKAYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSGDIAQGVNEALESREGDTDDLSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLAELRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEATNDQIRQDVIEKVIKAVIPADYLDDDTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNLVAAGLATKAEVQLAYAIGVAQPVSVRVDTFGTSTVPEAVLEAAVRQVFDLRPAGIIQMLDLKRPIYKQTAAYGHMGRTDIDLPWERLNKVDALVEAVKTVL
>NZ_LS483382.1|WP_076634356.1|1112767_1115146_-|leucine-rich-repeat-domain-containing-protein
MKTKKVIILVGLLLSSQLTLIACQSRGNGTYPIKTKQSRKGMTSNKIKPIKKSKKTNKTHKGVAGVDFPTDDGFILTKDSKILSKTDQGIVVDHDGHSHFIFYADLKGSPFEYLIPKGASLAKLAVAQQAASQGTSKVADPHHHYEFNPADIVAEDALGYTVRHDDHFHYILKSSLSGQTQAQAKQVATRLPQTSSLVSTATANGIPGLHFPTSDGFQFNGQGIVGVTKDSILVDHDGHLHPISFADLRQGGWAYVADQYDPAKKAEKPAETPHTPELSEREKEYQEKLAYLAEKLGIDPSTIKRVETQDGKLGLEYPHHDHAHVLMLSDIEIGKDIPDPHAIEHARELEKHKVGMDTLRALEFDEEVILDIVRTHDAPTPFPSNEKDPNKMKEWLATVIKLDLGSRKDPLQRKGLSLLPNLETLGIGFTPIKDISPVLQFKKLKRLLMTKTGVTDYRFLDNMPQLEGIDISQNNLKDISFLSKYKNLTLVAAADNGIEDIRPLGQLPNLKFLVLSNNKISDLSPLASLHQLQELHIDNNQITDLSPVSHKESLTVVDLSRNADVDLATLQAPNLETLMVNDTKVSHLDFLKNNPNLSSLSINRAQLQSLEGIEASSVIVRVEAEGNQIKSLVLKDKQGSLTFLDVTGNQLTSLEGVNNFTALDILSVSKNQLTNVNLSKPNKTVTNIDISHNNIPLADLKLNEQHIPEAIAKNFPAVYEGSMVGNGTAEEKAAMATKAKESAQEASESHDYNHNHAYEDEEGHAHEHRDKDDHDHEHEDENEAKDEQNHAD
>NZ_LS483382.1|WP_011017924.1|1115349_1116291_+|bifunctional-biotin--[acetyl-CoA-carboxylase]-synthetase/biotin-operon-repressor
MKTSEKIYQLLSQTDDFVSGEYLADQLSISRTSVWKSIKSLENQGIQIDSLKHKGYRMVQGDILLPKTISQGLGMPVTYTPHSQSTQLDAKQGIEAHNSAPRLYLAPSQEAAKGRLDRQFFSASTGGIYMSMYLKPNVPYADMPPYTMMVASSIVKAISRLTGIDTEIKWVNDIYLGNHKVAGILTEAITSVETGLITDVIIGVGLNFFVTDFPEAIAQKAGSLFTEKPTITRNDLIIDIWKLFLSIPVKDHVKVYKEKSLVLNKQVTFIENSQEKRAIAIDLTDQGHLIVQFDNGDLQTLRSGEISLSSWEN
>NZ_LS483382.1|WP_002992607.1|1116265_1116469_-|DUF3272-domain-containing-protein
MTIRQFLFMAFVCAFETYFFNDLLLSGNYLFALFWGLLLFRDLRRVHTINQLTKTILKTANSPKKKD
>NZ_LS483382.1|WP_023079397.1|1116563_1118234_-|DNA-polymerase-III-subunit-gamma/tau
MYQALYRKYRSQTFDEMVGQSVISKTLKQAVESGKISHAYLFSGPRGTGKTSAAKIFAKAMNCPNQVDGEPCNQCDICRDITNGSLEDVIEIDAASNNGVDEIRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPTENVVFILATTELHKIPATILSRVQRFEFKAIKQKAIREHLAWVLDKEGIAYEVDALNLIARRAEGGMRDALSILDQALSLSPDNQVTIAIAEEITGSISILALGDYVRYVSQEQATQALAALETIYDSGKSMSRFATDLLTYLRDLLVVKAGGDNQRQSAVFDTNLSLSIDRIFQMITVVTSHLPEIKKGTHPRIYAEMMTIQLAQKEQILSQANLSGELISEIETLKNELAQLKQQLSQLQSRPDSLARSDKTKPKTTSYRVDRVTILKIMEETVRNSQQSRQYLDALKNAWNEILDNISAQDRALLMGSEPVLANSENAILAFEAAFNAEQVMSRNNLNDMFGNIMSKAAGFSPNILAVPRTDFQHIRKEFAQQMKSQKDSVQEEQEVALDIPEGFDFLLDKINTIDD
>NZ_LS483382.1|WP_023079396.1|1118233_1118731_-|GAF-domain-containing-protein
MNKSKKIEQYQLMIAQAKELFANESNALANLSNASALLNMTLPNSVFAGFYLFDGQELILGPFQGRVSCVHIKLGKGVCGESAQSRRTIIINDVKQHANYISCDAAAMSEIVVPMVKESHLIGVLDLDSSLVADYDEVDQEYLEAFVDLLLEKTTFTFNMFGVKN
>NZ_LS483382.1|WP_014407658.1|1118875_1119685_+|PrsW-family-intramembrane-metalloprotease
MKQITQQKWLRYGLFIALVLNGIELELLGLTANNLSFKEAFALILTISLLGIYLIPFAAAIFYLSKKFHMNLNVIIVSCLSGLYISGFLASCGNHLVGQFWSYIIPSKDALKLWGDALTAPIVEEPIKASSAILVITLFPRLTLKEKLVIALLSGMGFQLTEDIRYLIQAKSIDSLVPTAIERISTAVTSHWVHTAIFTIGAYLLLKGSNLFSKQQQIFWLLSPLVLHFIWNSPLTSIPGMTVLLGTLILLIFGDLFQKINTLDDDVLF
>NZ_LS483382.1|WP_002984063.1|1119737_1120001_-|DUF1294-domain-containing-protein
MLLIWLGLLFVWNELVFVIYAFDKRKAIKKKRRISERKLLVITVLFGGFGALLAAKKYHHKTRKWYFVITWYTSILLTLLVTYIFMK
>NZ_LS483382.1|WP_002984060.1|1120080_1120707_-|uridine-kinase
MLKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYKDQSHMSFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKKHTRSNTTFRQDPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQYTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSKIASILGEV

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

36639 : 49025

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111721327.1\|36639_40365_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	3.5e-40	27.0
WP_009880323.1\|40598_42053_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.7e-54	32.7
WP_076634016.1\|42080_43103_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	1.5e-62	41.4
WP_009880321.1\|43270_43825_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	5.2e-25	36.1
WP_021733664.1\|44008_45556_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	2.6e-45	52.9
WP_002986694.1\|45613_46738_-	SH3 domain-containing protein	F8HGP2	Streptococcus_phage	7.7e-07	28.6
WP_076634015.1\|46990_48256_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_023079042.1\|48533_49025_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.4e-18	43.1

DBSCAN-SWA_2

337525 : 395138

Streptococcus_phage(33.33%)

protease,tRNA,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002985850.1\|337525_338116_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	2.6e-54	55.7
WP_002985847.1\|338610_338886_+	YlbG family protein	NA	NA	NA	NA
WP_014635306.1\|339134_339770_+	dTMP kinase	M1PSC7	Streptococcus_phage	2.0e-65	63.4
WP_011528291.1\|339787_340663_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	1.8e-72	47.9
WP_002985838.1\|341325_341649_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.3e-28	59.4
WP_021733048.1\|341653_342517_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	3.8e-115	74.7
WP_002985833.1\|342543_342936_+	hypothetical protein	NA	NA	NA	NA
WP_009880724.1\|342982_343612_-	copper homeostasis protein CutC	NA	NA	NA	NA
WP_076634276.1\|343911_344268_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.8e-39	65.0
WP_076634277.1\|344341_345169_-	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	1.7e-128	78.9
WP_002985826.1\|345402_346584_+	L-lactate oxidase	NA	NA	NA	NA
WP_076634278.1\|346849_351790_+\|protease	CXC chemokine-degrading serine protease SpyCEP	NA	NA	NA	NA
WP_042765607.1\|352561_353269_+	DUF1275 domain-containing protein	NA	NA	NA	NA
WP_076634279.1\|353508_355509_+\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	4.6e-87	35.1
WP_002995917.1\|356002_357016_+	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	5.5e-97	53.4
WP_002985812.1\|357019_357508_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	R4JF54	Bacillus_phage	1.3e-11	37.5
WP_076634280.1\|357474_359655_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	2.8e-170	43.3
WP_076634281.1\|359855_360608_-	ADP-ribosyltransferase	NA	NA	NA	NA
WP_076634282.1\|361066_361546_+	hypothetical protein	NA	NA	NA	NA
WP_076634283.1\|362051_362492_+	hypothetical protein	NA	NA	NA	NA
WP_021340584.1\|362680_362932_+	hypothetical protein	NA	NA	NA	NA
WP_076634284.1\|363027_363660_-	hypothetical protein	NA	NA	NA	NA
WP_002990844.1\|364702_364939_+	DUF2829 domain-containing protein	NA	NA	NA	NA
WP_011017438.1\|364931_365630_+	3-oxoacyl-ACP reductase	A0A0N9R355	Chrysochromulina_ericina_virus	7.1e-11	25.6
WP_076634285.1\|365704_366664_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_002993065.1\|366996_368334_+	MFS transporter	NA	NA	NA	NA
WP_076634286.1\|368506_369889_+	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L4K9	Tupanvirus	8.5e-32	36.0
WP_002985793.1\|369919_370474_+	NUDIX hydrolase	NA	NA	NA	NA
WP_023078625.1\|370473_370725_+	hypothetical protein	NA	NA	NA	NA
WP_010921957.1\|370743_371439_+	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_023078629.1\|371589_371931_+	hypothetical protein	NA	NA	NA	NA
WP_023078622.1\|372031_372679_-	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_004218965.1\|372824_373757_+	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002985780.1\|373820_374546_+	metal ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.4e-17	32.6
WP_011017448.1\|374546_375401_+	metal ABC transporter permease	NA	NA	NA	NA
WP_030126994.1\|375548_376355_-	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.5e-20	36.6
WP_076634287.1\|376571_378977_+	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	3.8e-88	51.7
WP_002990803.1\|379046_379400_-	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_002990800.1\|379643_380069_+	50S ribosomal protein L11	NA	NA	NA	NA
WP_002985768.1\|380174_380864_+	50S ribosomal protein L1	NA	NA	NA	NA
WP_002985765.1\|381185_381914_+	UMP kinase	NA	NA	NA	NA
WP_076634288.1\|381942_382500_+	ribosome recycling factor	NA	NA	NA	NA
WP_076634289.1\|382608_383466_+	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_011284570.1\|383538_384048_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_021340760.1\|384044_384260_+	YozE family protein	NA	NA	NA	NA
WP_076634290.1\|384415_385597_+	LysM peptidoglycan-binding domain-containing protein	A0A0E3XB61	Gordonia_phage	2.1e-15	39.6
WP_023078789.1\|385912_387685_+	oleate hydratase	NA	NA	NA	NA
WP_010921967.1\|387843_388896_+	PhoH family protein	W8D063	Erwinia_phage	1.2e-46	50.0
WP_076634291.1\|388941_389517_+	uracil-DNA glycosylase family protein	NA	NA	NA	NA
WP_002985748.1\|389675_390173_+	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_002985746.1\|390153_390561_+	diacylglycerol kinase	NA	NA	NA	NA
WP_014635331.1\|390680_391577_+	GTPase Era	NA	NA	NA	NA
WP_014635332.1\|391596_392073_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_002994504.1\|393030_393276_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_002987564.1\|393290_393473_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_076634339.1\|394676_394925_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_076634292.1\|394937_395138_+\|bacteriocin	bacteriocin	NA	NA	NA	NA

DBSCAN-SWA_3

526943 : 591602

Temperate_phage(47.37%)

integrase,holin,terminase,capsid,tail,portal,tRNA

attL 522100:522117|attR 601644:601661

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
522100:522117	attL	NA	NA	NA	NA
WP_002985437.1\|526943_528290_+\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.1e-55	30.8
WP_002985434.1\|528702_529593_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	8.8e-06	29.8
WP_076634335.1\|529589_530567_+	YvcK family protein	A1IMD5	Streptococcus_phage	7.3e-139	74.2
WP_011054317.1\|530563_531475_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.0e-105	64.7
WP_023078725.1\|531607_533005_+	C69 family dipeptidase	NA	NA	NA	NA
WP_076634119.1\|533156_534704_+	zinc ABC transporter substrate-binding protein AdcA	NA	NA	NA	NA
WP_076634118.1\|534850_535573_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_111721351.1\|535591_536791_+	SIS domain-containing protein	NA	NA	NA	NA
WP_002985307.1\|536887_537148_-	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_011528442.1\|537262_538204_-	bifunctional oligoribonuclease/PAP phosphatase NrnA	NA	NA	NA	NA
WP_002985303.1\|538597_539047_+	flavodoxin	NA	NA	NA	NA
WP_002994052.1\|539221_539506_+	chorismate mutase	NA	NA	NA	NA
WP_076634117.1\|539498_540761_+	voltage-gated chloride channel family protein	A0A1X9I5Z9	Streptococcus_phage	1.1e-94	51.3
WP_002985298.1\|540875_541223_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_023612372.1\|541586_542663_-\|integrase	site-specific integrase	Q0R5B4	Streptococcus_phage	7.5e-68	41.2
WP_023612337.1\|542781_543303_-	hypothetical protein	Q938N8	Temperate_phage	7.5e-66	97.7
WP_030126053.1\|543313_543691_-	ImmA/IrrE family metallo-endopeptidase	A0A1P8VVK5	Streptococcus_phage	1.6e-54	77.6
WP_023611288.1\|543674_544034_-	helix-turn-helix transcriptional regulator	A0A1P8VVN3	Streptococcus_phage	1.7e-56	95.0
WP_023612341.1\|544221_544440_+	helix-turn-helix transcriptional regulator	A0A1P8VVR5	Streptococcus_phage	5.9e-33	97.2
WP_023612302.1\|544539_544770_+	hypothetical protein	NA	NA	NA	NA
WP_164492191.1\|544753_544897_+	hypothetical protein	A0A1P8VVR9	Streptococcus_phage	3.4e-13	83.7
WP_023612348.1\|544906_545125_+	hypothetical protein	NA	NA	NA	NA
WP_003056170.1\|545126_545369_+	hypothetical protein	NA	NA	NA	NA
WP_023612340.1\|545355_546672_+	AAA family ATPase	A0A097BY67	Enterococcus_phage	7.8e-152	63.8
WP_003056188.1\|546686_547769_+	AAA family ATPase	A0A0K2CZH1	Paenibacillus_phage	2.5e-103	53.3
WP_003056185.1\|547963_548557_+	hypothetical protein	A0A097BY29	Enterococcus_phage	1.7e-29	43.5
WP_080262841.1\|548556_550140_+	DEAD/DEAH box helicase	A0A097BY72	Enterococcus_phage	2.0e-234	77.8
WP_023612331.1\|550152_550347_+	hypothetical protein	NA	NA	NA	NA
WP_023612365.1\|550369_552613_+	AAA family ATPase	Q5YA88	Bacillus_phage	4.7e-282	63.7
WP_003059078.1\|552904_553087_+	hypothetical protein	NA	NA	NA	NA
WP_023612320.1\|553079_553475_+	RusA family crossover junction endodeoxyribonuclease	Q5YA86	Bacillus_phage	1.8e-40	58.8
WP_023612313.1\|553471_553696_+	hypothetical protein	NA	NA	NA	NA
WP_023612326.1\|553698_553884_+	hypothetical protein	A3F626	Streptococcus_phage	6.6e-09	82.9
WP_023612315.1\|553880_554132_+	hypothetical protein	NA	NA	NA	NA
WP_023612304.1\|554115_554520_+	hypothetical protein	A3F627	Streptococcus_phage	1.6e-39	65.2
WP_014411870.1\|554516_554801_+	hypothetical protein	A0A097PAV1	Streptococcus_pyogenes_phage	1.4e-37	89.4
WP_011018133.1\|554802_555435_+	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	2.3e-85	68.6
WP_014411869.1\|555437_556148_+	DUF1642 domain-containing protein	Q938L9	Temperate_phage	3.0e-25	46.2
WP_014411868.1\|556144_556516_+	hypothetical protein	NA	NA	NA	NA
WP_021340586.1\|556783_557221_+	DUF1492 domain-containing protein	A0A097PBF1	Streptococcus_pyogenes_phage	1.4e-76	99.3
WP_011054748.1\|557739_557997_-	hypothetical protein	NA	NA	NA	NA
WP_002986854.1\|558077_558596_+	ParB N-terminal domain-containing protein	Q938L7	Temperate_phage	1.5e-90	100.0
WP_002986850.1\|558574_559252_+	hypothetical protein	Q938L6	Temperate_phage	8.7e-131	100.0
WP_002986845.1\|559374_559644_+	hypothetical protein	B5SP24	Lactococcus_phage	2.8e-16	51.1
WP_002986841.1\|559704_560082_+	ASCH domain-containing protein	Q938L5	Temperate_phage	1.7e-67	100.0
WP_023612332.1\|560132_560606_+	hypothetical protein	Q938L4	Temperate_phage	7.3e-76	98.7
WP_010922074.1\|560688_561900_+\|terminase	PBSX family phage terminase large subunit	Q938L3	Temperate_phage	3.7e-225	99.7
WP_002986832.1\|561913_563416_+\|portal	phage portal protein	Q938L2	Temperate_phage	5.4e-282	100.0
WP_011054746.1\|563420_564899_+\|capsid	phage minor capsid protein	Q938L1	Temperate_phage	8.2e-275	100.0
WP_002986829.1\|564870_565110_+	hypothetical protein	Q938L0	Temperate_phage	2.8e-36	100.0
WP_011054745.1\|565171_565438_+	hypothetical protein	Q938K9	Temperate_phage	1.5e-38	100.0
WP_011106689.1\|565563_566178_+	hypothetical protein	Q938K8	Temperate_phage	1.3e-96	100.0
WP_010922080.1\|566181_567000_+\|capsid	N4-gp56 family major capsid protein	Q79S85	Temperate_phage	4.0e-146	100.0
WP_011054743.1\|567053_567470_+	hypothetical protein	Q938K7	Temperate_phage	1.1e-56	100.0
WP_010922082.1\|567459_567792_+	hypothetical protein	Q79S86	Temperate_phage	9.6e-59	100.0
WP_010922083.1\|567791_568148_+	hypothetical protein	Q79S88	Temperate_phage	4.5e-62	100.0
WP_010922084.1\|568144_568543_+\|capsid	phage capsid protein	Q79S87	Temperate_phage	3.5e-71	100.0
WP_011054741.1\|568542_569028_+	hypothetical protein	Q938K6	Temperate_phage	1.6e-86	100.0
WP_011054740.1\|569066_569501_+	hypothetical protein	Q938K5	Temperate_phage	2.6e-72	100.0
WP_011284973.1\|569504_570086_+	hypothetical protein	Q938K4	Temperate_phage	4.9e-106	99.5
WP_023612368.1\|570075_573336_+	tape measure protein	Q938K3	Temperate_phage	0.0e+00	99.5
WP_011054737.1\|573332_574049_+\|tail	phage tail family protein	Q938K2	Temperate_phage	2.9e-137	100.0
WP_011284971.1\|574045_576193_+\|tail	phage tail protein	Q938K1	Temperate_phage	0.0e+00	95.9
WP_011284843.1\|576189_577404_+	hypothetical protein	A3F657	Streptococcus_phage	5.0e-44	49.5
WP_011284842.1\|577390_577720_+	hypothetical protein	NA	NA	NA	NA
WP_047235372.1\|577730_579620_+	gp58-like family protein	Q938J9	Temperate_phage	1.4e-189	75.6
WP_002988448.1\|579631_580060_+	DUF1617 family protein	Q938J8	Temperate_phage	8.1e-58	84.3
WP_011054443.1\|580062_580695_+	hypothetical protein	Q938J7	Temperate_phage	2.0e-44	49.5
WP_011017397.1\|580706_580979_+	hypothetical protein	A7J2B2	Streptococcus_phage	5.5e-36	91.0
WP_011054444.1\|580975_581203_+\|holin	phage holin	A7J2B3	Streptococcus_phage	7.6e-31	98.7
WP_011054445.1\|581318_582527_+	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	2.9e-214	87.5
WP_050440680.1\|582636_583623_-	DNA/RNA non-specific endonuclease	A7J2B8	Streptococcus_phage	5.2e-169	99.7
WP_030127450.1\|583855_584035_+	hypothetical protein	A3F673	Streptococcus_phage	3.4e-18	77.6
WP_168389163.1\|584868_585438_+	HAD-IA family hydrolase	NA	NA	NA	NA
WP_002994058.1\|585438_587391_+	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	8.9e-144	46.3
WP_002990455.1\|587747_589472_+	septation ring formation regulator EzrA	NA	NA	NA	NA
WP_002990451.1\|589603_590062_-	YueI family protein	W6LLD2	Streptococcus_phage	1.8e-18	39.1
WP_002985288.1\|590294_591602_+	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	1.2e-240	96.6
601644:601661	attR	NA	NA	NA	NA

DBSCAN-SWA_4

666542 : 677145

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011054348.1\|666542_668753_-	LTA synthase family protein	W6LM83	Streptococcus_phage	2.9e-268	69.1
WP_002985142.1\|668860_670024_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	3.4e-143	65.1
WP_023610850.1\|670020_670707_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	5.4e-88	68.9
WP_002990262.1\|670800_671967_+	chorismate synthase	A0A291AU41	Pandoravirus	4.5e-34	32.8
WP_011054350.1\|672027_672369_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	1.3e-18	39.3
WP_023610863.1\|672589_673942_+	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	1.6e-30	24.2
WP_023610854.1\|674029_675298_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_012560601.1\|675327_675768_-	hypothetical protein	NA	NA	NA	NA
WP_011184383.1\|676002_677145_+	cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	1.4e-24	27.3

DBSCAN-SWA_5

777601 : 818480

Streptococcus_phage(60.78%)

integrase,terminase,capsid,tail,portal,tRNA

attL 782994:783042|attR 819577:819625

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023610980.1\|777601_778288_+\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_023611011.1\|778277_779066_+	Nif3-like dinuclear metal center hexameric protein	NA	NA	NA	NA
WP_023610975.1\|779105_780212_+	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_014407521.1\|780269_781139_+	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	5.4e-101	64.2
WP_002990099.1\|781138_781732_+	dTDP-4-dehydrorhamnose 3,5-epimerase	H9NC63	Sphingomonas_phage	3.7e-08	28.2
WP_023610978.1\|781975_783016_+	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	1.5e-68	43.9
782994:783042	attL	NA	NA	NA	NA
WP_002990094.1\|783098_784238_-\|integrase	site-specific integrase	A1EAB7	Streptococcus_phage	3.4e-119	56.3
WP_076634078.1\|784365_784632_-	DUF4177 domain-containing protein	NA	NA	NA	NA
WP_076634077.1\|784643_785024_-	ImmA/IrrE family metallo-endopeptidase	A0A1S5SFH2	Streptococcus_phage	2.0e-39	60.3
WP_002994741.1\|785027_785375_-	helix-turn-helix transcriptional regulator	A0A1S5SEQ8	Streptococcus_phage	1.2e-40	72.6
WP_020837683.1\|785797_785893_-	type I toxin-antitoxin system Fst family toxin	NA	NA	NA	NA
WP_002993390.1\|786528_786720_+	hypothetical protein	A7J270	Streptococcus_phage	4.0e-25	92.1
WP_111721359.1\|786731_787448_+	phage antirepressor KilAC domain-containing protein	C9WB91	Streptococcus_virus	1.1e-102	76.3
WP_011889039.1\|787588_787771_-	hypothetical protein	NA	NA	NA	NA
WP_111721361.1\|787877_788189_+	excisionase	A1EAC3	Streptococcus_phage	2.5e-48	85.4
WP_032461153.1\|788190_788376_+	hypothetical protein	Q938N3	Temperate_phage	1.8e-22	90.2
WP_076634492.1\|788475_788745_+	transcriptional regulator	A0A060QMU7	Streptococcus_phage	2.5e-12	46.3
WP_172451688.1\|788845_789259_+	DnaD domain protein	Q938N2	Temperate_phage	5.4e-59	84.7
WP_002985387.1\|789239_789473_+	hypothetical protein	Q938N1	Temperate_phage	6.1e-36	94.8
WP_111721363.1\|789469_789610_+	hypothetical protein	A0A1X9I6Y1	Streptococcus_phage	1.5e-05	56.8
WP_076634490.1\|789618_789825_+	hypothetical protein	NA	NA	NA	NA
WP_076634469.1\|789880_790210_+	hypothetical protein	J7KGX3	Streptococcus_phage	9.3e-46	86.2
WP_053308489.1\|790212_791142_+	recombinase RecT	M1NRN6	Streptococcus_phage	1.2e-90	71.8
WP_111721364.1\|791138_791936_+	PD-(D/E)XK nuclease-like domain-containing protein	J7KGZ1	Streptococcus_phage	6.6e-130	83.8
WP_011285624.1\|791945_792113_+	hypothetical protein	A0A1S5SEF3	Streptococcus_phage	3.3e-07	51.9
WP_076634192.1\|792289_792631_+	hypothetical protein	NA	NA	NA	NA
WP_076634193.1\|792627_793140_+	hypothetical protein	Q708P9	Streptococcus_phage	1.1e-61	73.2
WP_076634194.1\|793126_793321_+	hypothetical protein	A3F626	Streptococcus_phage	9.7e-11	89.2
WP_076634195.1\|793317_793587_+	hypothetical protein	A7J287	Streptococcus_phage	2.9e-29	80.9
WP_033888177.1\|793589_794075_+	class I SAM-dependent methyltransferase	A0A097PAU8	Streptococcus_pyogenes_phage	3.5e-81	83.8
WP_076634196.1\|794076_794709_+	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	5.9e-81	65.7
WP_002994112.1\|795109_795550_+	DUF1492 domain-containing protein	A0A0B5A564	Streptococcus_phage	3.5e-24	50.4
WP_002994108.1\|795631_795976_+	HNH endonuclease	M1Q0W7	Streptococcus_phage	6.5e-42	69.4
WP_002994106.1\|796125_796482_+	hypothetical protein	M1PRL3	Streptococcus_phage	2.4e-07	57.8
WP_076634197.1\|796478_797747_+\|portal	phage portal protein	A0A1X9I693	Streptococcus_phage	5.9e-189	75.8
WP_002994100.1\|799237_799462_+	hypothetical protein	NA	NA	NA	NA
WP_032461150.1\|799511_799691_+	hypothetical protein	NA	NA	NA	NA
WP_002986828.1\|799683_799950_+	hypothetical protein	Q938K9	Temperate_phage	6.4e-37	95.5
WP_011888764.1\|799951_800188_+	hypothetical protein	M1IRA5	Streptococcus_phage	1.2e-31	80.3
WP_011285619.1\|800269_801685_+\|terminase	terminase	A0A0B5A091	Streptococcus_phage	2.9e-213	74.2
WP_053308482.1\|801765_802230_+	DUF4355 domain-containing protein	A0A141E167	Streptococcus_phage	6.3e-40	57.8
WP_053308481.1\|802233_803127_+\|capsid	phage major capsid protein	A0A126GGI3	Streptococcus_phage	6.3e-129	77.4
WP_053308480.1\|803277_803700_+	hypothetical protein	A0A0B5A2F6	Streptococcus_phage	1.3e-47	68.6
WP_011054681.1\|803659_803998_+	hypothetical protein	A0A0B5A086	Streptococcus_phage	8.1e-45	75.0
WP_053308479.1\|803990_804227_+	hypothetical protein	A0A0B5A7G2	Streptococcus_phage	1.9e-21	71.4
WP_000573598.1\|804227_804563_+	hypothetical protein	A0A1P8BMR5	Lactococcus_phage	9.8e-35	64.9
WP_076634199.1\|804578_805169_+\|tail	phage tail protein	M1PKG8	Streptococcus_phage	2.4e-60	63.0
WP_002991567.1\|805179_805443_+	hypothetical protein	A0A0B5A2F3	Streptococcus_phage	2.9e-18	54.7
WP_002991564.1\|805457_805829_+	DUF5361 domain-containing protein	M1PL84	Streptococcus_phage	9.2e-34	59.2
WP_002991560.1\|805828_806428_+	hypothetical protein	Q38126	Lactococcus_phage	3.6e-56	64.3
WP_011017973.1\|806528_807089_+	HNH endonuclease	A0A1B1IM39	Lactococcus_phage	1.0e-84	84.4
WP_076634200.1\|809101_809797_+	hypothetical protein	A0A1B1P761	Bacillus_phage	7.6e-05	29.6
WP_053308476.1\|809793_811752_+\|tail	phage tail protein	M1PKG3	Streptococcus_phage	5.3e-96	49.2
WP_053308475.1\|811751_812861_+	hyaluronoglucosaminidase	A7J2A8	Streptococcus_phage	3.5e-113	66.1
WP_076634201.1\|812875_814657_+	hypothetical protein	Q938J9	Temperate_phage	6.1e-67	40.5
WP_076634202.1\|814665_815094_+	DUF1617 family protein	Q938J8	Temperate_phage	1.1e-54	81.4
WP_076634203.1\|815096_815729_+	hypothetical protein	Q938J7	Temperate_phage	1.5e-47	52.9
WP_002990012.1\|815739_816036_+	hypothetical protein	Q938J6	Temperate_phage	3.7e-46	98.0
WP_002990010.1\|816032_816218_+	hypothetical protein	Q938J5	Temperate_phage	1.9e-24	95.1
WP_076634204.1\|816328_817534_+	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	3.7e-209	85.5
WP_047373492.1\|817802_818480_+	streptococcal pyrogenic exotoxin SpeI	A0A075M4C7	Staphylococcus_phage	2.4e-27	32.4
819577:819625	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1350067 : 1423253

Streptococcus_phage(73.21%)

integrase,terminase,capsid,tail,portal,tRNA,head

attL 1379048:1379064|attR 1419849:1419865

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076634148.1\|1350067_1352107_-\|tRNA	glycine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_111721397.1\|1352485_1353403_-\|tRNA	glycine--tRNA ligase subunit alpha	NA	NA	NA	NA
WP_002983542.1\|1353774_1354308_-	isoprenylcysteine carboxyl methyltransferase family protein	NA	NA	NA	NA
WP_002994275.1\|1354439_1355279_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	4.9e-51	40.7
WP_076634147.1\|1355400_1356549_-	N-acetylglucosamine-6-phosphate deacetylase	NA	NA	NA	NA
WP_002988856.1\|1356666_1358298_-	Na/Pi cotransporter family protein	A0A1B1ITU5	uncultured_Mediterranean_phage	2.7e-05	38.8
WP_076634146.1\|1358499_1359222_+	hypothetical protein	NA	NA	NA	NA
WP_002988852.1\|1359350_1360193_-	DegV family protein	A0A1X9I5J4	Streptococcus_phage	1.3e-91	61.9
WP_010922569.1\|1360485_1361043_+	TetR/AcrR family transcriptional regulator	A0A1X9I6A2	Streptococcus_phage	3.2e-14	60.3
WP_076634145.1\|1361078_1361903_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_002994286.1\|1361904_1362522_-	trimeric intracellular cation channel family protein	NA	NA	NA	NA
WP_011106626.1\|1362707_1363685_-	tagatose-bisphosphate aldolase	NA	NA	NA	NA
WP_012560884.1\|1363766_1364030_-	tagatose-6-phosphate kinase	NA	NA	NA	NA
WP_023609931.1\|1364183_1364699_-	galactose-6-phosphate isomerase subunit LacB	NA	NA	NA	NA
WP_010922573.1\|1364713_1365139_-	galactose-6-phosphate isomerase subunit LacA	A0A222YX14	Synechococcus_phage	2.2e-07	28.6
WP_002994298.1\|1365395_1366847_-	PTS galactitol transporter subunit IIC	NA	NA	NA	NA
WP_002988834.1\|1366872_1367178_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_010922576.1\|1367170_1367644_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_002983505.1\|1367880_1368651_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	6.4e-21	27.8
WP_023078711.1\|1368854_1369058_-	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_023078661.1\|1369071_1371303_-	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	7.6e-115	37.6
WP_023078699.1\|1371302_1371737_-	CopY/TcrY family copper transport repressor	NA	NA	NA	NA
WP_023078696.1\|1371908_1372898_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_023611916.1\|1373028_1373379_-	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_076634143.1\|1373584_1376446_-	translation initiation factor IF-2	E3T4N3	Cafeteria_roenbergensis_virus	1.2e-19	25.4
WP_002983488.1\|1376465_1376768_-	YlxQ-related RNA-binding protein	NA	NA	NA	NA
WP_002983486.1\|1376760_1377057_-	YlxR family protein	NA	NA	NA	NA
WP_002988817.1\|1377072_1378230_-	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_002988815.1\|1378404_1378941_-	ribosome maturation factor RimP	NA	NA	NA	NA
1379048:1379064	attL	NA	NA	NA	NA
WP_002988813.1\|1379185_1379365_-	hypothetical protein	A3F673	Streptococcus_phage	5.6e-21	83.1
WP_002988811.1\|1379603_1380776_+	streptodornase Sda1	A7J2B8	Streptococcus_phage	4.7e-76	49.8
WP_002988807.1\|1380891_1382088_-	streptodornase Sda1	Q938J4	Temperate_phage	6.1e-196	82.2
WP_021341107.1\|1382198_1382384_-	hypothetical protein	Q938J5	Temperate_phage	6.2e-23	91.8
WP_002988799.1\|1382380_1382680_-	hypothetical protein	Q938J6	Temperate_phage	3.5e-36	82.3
WP_002988797.1\|1382690_1383311_-	hypothetical protein	A3F662	Streptococcus_phage	8.3e-80	88.8
WP_002988795.1\|1383313_1383475_-	hypothetical protein	NA	NA	NA	NA
WP_021341125.1\|1383483_1385391_-	gp58-like family protein	Q938J9	Temperate_phage	3.8e-139	61.7
WP_021341117.1\|1385401_1386037_-	hypothetical protein	A0A097PBF7	Streptococcus_pyogenes_phage	2.2e-75	67.6
WP_002988439.1\|1386036_1387092_-	hypothetical protein	A3F657	Streptococcus_phage	1.2e-126	73.2
WP_002988790.1\|1387088_1389071_-\|tail	phage tail protein	A7J2A7	Streptococcus_phage	0.0e+00	92.5
WP_002988788.1\|1389080_1389923_-	hypothetical protein	A7J2A6	Streptococcus_phage	8.5e-160	99.6
WP_002988786.1\|1389934_1394317_-	tape measure protein	A7J2A5	Streptococcus_phage	3.2e-226	76.4
WP_002983445.1\|1394331_1394565_-	hypothetical protein	A7J2A4	Streptococcus_phage	4.4e-34	100.0
WP_002983443.1\|1394639_1395095_-	hypothetical protein	A7J2A3	Streptococcus_phage	8.3e-77	100.0
WP_002988784.1\|1395148_1395748_-\|tail	phage major tail protein, TP901-1 family	A7J2A2	Streptococcus_phage	4.1e-92	98.9
WP_002988782.1\|1395759_1396119_-	hypothetical protein	A7J2A1	Streptococcus_phage	6.8e-58	97.5
WP_002988781.1\|1396122_1396467_-	HK97 gp10 family phage protein	A7J2A0	Streptococcus_phage	6.1e-56	99.1
WP_000639437.1\|1396463_1396742_-	hypothetical protein	A7J299	Streptococcus_phage	4.2e-47	98.9
WP_002988776.1\|1396752_1397109_-\|head,tail	phage head-tail connector protein	A7J298	Streptococcus_phage	2.8e-56	97.5
WP_002988771.1\|1397120_1398008_-	hypothetical protein	A7J297	Streptococcus_phage	3.6e-161	99.7
WP_002988768.1\|1398020_1398590_-	DUF4355 domain-containing protein	A7J296	Streptococcus_phage	2.6e-80	97.9
WP_002988765.1\|1398745_1399012_-	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	1.7e-34	88.6
WP_002983423.1\|1399014_1399203_-	hypothetical protein	A7J294	Streptococcus_phage	1.4e-22	98.4
WP_015446273.1\|1399233_1400679_-\|capsid	minor capsid protein	A7J293	Streptococcus_phage	3.4e-257	92.9
WP_002988758.1\|1400638_1402171_-\|portal	phage portal protein	A7J292	Streptococcus_phage	1.3e-286	98.2
WP_002988754.1\|1402186_1403464_-\|terminase	PBSX family phage terminase large subunit	A7J291	Streptococcus_phage	1.3e-241	97.6
WP_011106637.1\|1403453_1403906_-\|terminase	terminase small subunit	A7J290	Streptococcus_phage	6.9e-76	100.0
WP_002988747.1\|1403995_1404412_-	DUF722 domain-containing protein	A7J289	Streptococcus_phage	6.6e-73	100.0
WP_002988743.1\|1404408_1404600_-	hypothetical protein	NA	NA	NA	NA
WP_002988740.1\|1404589_1405441_-	site-specific DNA-methyltransferase	A0A1W6JMZ7	Lactococcus_phage	1.5e-100	71.9
WP_002988738.1\|1405449_1405716_-	hypothetical protein	A7J287	Streptococcus_phage	5.4e-20	65.2
WP_002988735.1\|1405712_1405880_-	hypothetical protein	A7J285	Streptococcus_phage	1.9e-23	94.5
WP_002988733.1\|1405880_1407203_-	DEAD/DEAH box helicase family protein	A7J284	Streptococcus_phage	1.9e-254	98.4
WP_002988730.1\|1407199_1407475_-	VRR-NUC domain-containing protein	A7J283	Streptococcus_phage	9.1e-47	100.0
WP_011285674.1\|1407861_1410246_-	DNA primase	A7J282	Streptococcus_phage	4.1e-276	94.4
WP_002988723.1\|1410250_1412173_-	DNA polymerase	A7J280	Streptococcus_phage	0.0e+00	96.7
WP_002988718.1\|1412215_1412773_-	DUF2815 family protein	D2J040	Enterococcus_phage	2.5e-51	57.9
WP_002988715.1\|1412783_1413182_-	hypothetical protein	NA	NA	NA	NA
WP_002988711.1\|1413185_1414340_-	DUF2800 domain-containing protein	A7J278	Streptococcus_phage	4.5e-204	91.9
WP_002988708.1\|1414339_1414639_-	hypothetical protein	A7J277	Streptococcus_phage	1.8e-43	100.0
WP_002988705.1\|1414726_1414930_-	hypothetical protein	A7J276	Streptococcus_phage	2.3e-31	95.5
WP_002988700.1\|1415076_1415463_-	hypothetical protein	A7J274	Streptococcus_phage	3.1e-56	88.2
WP_002988697.1\|1415459_1415663_-	hypothetical protein	NA	NA	NA	NA
WP_002988693.1\|1415655_1415826_-	hypothetical protein	A7J273	Streptococcus_phage	6.9e-21	89.3
WP_002988687.1\|1415822_1416098_-	hypothetical protein	A7J272	Streptococcus_phage	5.9e-46	95.6
WP_002988684.1\|1416159_1416375_-	hypothetical protein	M1Q1B4	Streptococcus_phage	4.2e-23	76.8
WP_002988681.1\|1416422_1416836_+	hypothetical protein	NA	NA	NA	NA
WP_002988678.1\|1416816_1416972_-	hypothetical protein	NA	NA	NA	NA
WP_011285676.1\|1417246_1417648_+	helix-turn-helix transcriptional regulator	A7J269	Streptococcus_phage	1.1e-40	72.9
WP_002988673.1\|1417661_1418045_+	hypothetical protein	A7J268	Streptococcus_phage	5.3e-69	99.2
WP_002988670.1\|1418055_1418607_+	hypothetical protein	A7J267	Streptococcus_phage	3.4e-85	92.3
WP_002988667.1\|1418723_1419803_+\|integrase	site-specific integrase	A7J266	Streptococcus_phage	1.3e-176	86.9
WP_002983387.1\|1420000_1420636_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
1419849:1419865	attR	NA	NA	NA	NA
WP_002983385.1\|1420635_1421427_-	phosphotransferase family protein	NA	NA	NA	NA
WP_076634067.1\|1421490_1422525_-	ABC transporter permease	NA	NA	NA	NA
WP_002983379.1\|1422527_1423253_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	3.9e-20	28.0

DBSCAN-SWA_7

1766813 : 1788356

Streptococcus_phage(62.5%)

tRNA,integrase,holin

attL 1770012:1770032|attR 1782902:1782922

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076634444.1\|1766813_1768034_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	4.6e-05	23.6
WP_023610727.1\|1768044_1770027_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	2.3e-62	30.1
1770012:1770032	attL	NA	NA	NA	NA
WP_021299091.1\|1770121_1771267_-\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	2.7e-84	44.9
WP_110410861.1\|1771594_1771738_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_003049853.1\|1773261_1773450_+	helix-turn-helix domain-containing protein	A0A1X9I5U7	Streptococcus_phage	4.8e-07	45.2
WP_076634445.1\|1773465_1774074_+	phage repressor protein	A0A1W6JPC3	Staphylococcus_phage	2.7e-43	48.0
WP_021733977.1\|1774094_1774502_+	hypothetical protein	A0A1X9I5V7	Streptococcus_phage	3.8e-49	68.7
WP_076634446.1\|1774514_1774847_+	hypothetical protein	NA	NA	NA	NA
WP_037588219.1\|1775102_1775444_+	hypothetical protein	NA	NA	NA	NA
WP_003058793.1\|1775430_1775652_+	hypothetical protein	NA	NA	NA	NA
WP_003058790.1\|1775654_1775846_+	hypothetical protein	NA	NA	NA	NA
WP_003058810.1\|1775857_1776187_+	hypothetical protein	NA	NA	NA	NA
WP_001100459.1\|1776189_1776462_+	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	6.1e-19	60.0
WP_003058743.1\|1776462_1777320_+	primase C-terminal domain-containing protein	A0A1X9I6L2	Streptococcus_phage	3.4e-124	74.8
WP_076634447.1\|1777288_1778977_+	DNA primase	A0A1X9I717	Streptococcus_phage	5.5e-259	82.1
WP_003045773.1\|1779263_1779437_+	hypothetical protein	A0A1X9I5U0	Streptococcus_phage	6.6e-11	59.6
WP_003058787.1\|1779442_1779616_+	hypothetical protein	NA	NA	NA	NA
WP_003058776.1\|1779617_1780127_+	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	3.0e-27	60.4
WP_003058746.1\|1780201_1780690_+	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	3.1e-45	54.9
WP_003058730.1\|1781092_1781455_+	DUF1492 domain-containing protein	A0A2H4JFS1	uncultured_Caudovirales_phage	8.7e-05	29.9
WP_003058801.1\|1781429_1781813_+	ArpU family transcriptional regulator	J7KDQ1	Streptococcus_phage	1.7e-14	41.7
WP_076634449.1\|1782017_1782650_+	hypothetical protein	NA	NA	NA	NA
WP_076634450.1\|1783045_1785601_-	DNA mismatch repair protein MutS	A0A1V0SGG8	Hokovirus	2.6e-42	23.7
1782902:1782922	attR	NA	NA	NA	NA
WP_011889237.1\|1785587_1785794_-	YlbF family regulator	NA	NA	NA	NA
WP_023610766.1\|1785936_1786374_-	arginine repressor	NA	NA	NA	NA
WP_023610730.1\|1786664_1788356_+\|tRNA	arginine--tRNA ligase	A0A2I2L3K1	Orpheovirus	6.4e-74	32.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage