CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483386	Streptococcus pyogenes strain NCTC13742 chromosome 1	2 crisprs	DinG,csm6,RT,cas3,DEDDh,csa3	0	1	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483386_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483386_1

828928-829146

Orphan

II-A

Consensus_repeat	Method
TGTTTTGAATGGTCCCAAAAC	CRT

3 spacers

The CRISPR arrays of NZ_LS483386_1

>merge|NZ_LS483386|1|828928-829146|CRT
TGTTTTGAATGGTCCCAAAACGATTAGCTCAAGCATGCCTTTATAAATGTCGTTTTAGAGCTATGTTGTGTTGAATGGTCCCAAAACCAGCTTGGATTTAATAGCAGACCATGTTTTGTTTTAGAGCTATGTTGTTTTGAATGGTCCCAAAACGCACGAGTTTAACTCCCTTATTATTAGCTTGTTTTAGAGCTATGCTGTTTTGAATGGTCTCCATTC

>NZ_LS483386|1|1|828928-829146|CRT
TGTTTTGAATGGTCCCAAAAC	GATTAGCTCAAGCATGCCTTTATAAATGTCGTTTTAGAGCTATGT
TGTGTTGAATGGTCCCAAAAC	CAGCTTGGATTTAATAGCAGACCATGTTTTGTTTTAGAGCTATGT
TGTTTTGAATGGTCCCAAAAC	GCACGAGTTTAACTCCCTTATTATTAGCTTGTTTTAGAGCTATGC
TGTTTTGAATGGTCTCCATTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483386.1\|WP_050336191.1\|826611_827364_+\|acyl-[acyl-carrier-protein]-thioesterase	unknown	unknown	gnl\|CDD\|226401
NZ_LS483386.1\|WP_023611114.1\|819980_821324_-\|Mur-ligase-family-protein	unknown	unknown	gnl\|CDD\|223840
NZ_LS483386.1\|WP_023612009.1\|829789_831622_+\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_LS483386.1\|WP_023611142.1\|827363_828128_+\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_LS483386.1\|WP_023612035.1\|833859_834879_+\|YeiH-family-putative-sulfate-export-transporter	unknown	unknown	gnl\|CDD\|225411
NZ_LS483386.1\|WP_002989935.1\|835085_835511_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
NZ_LS483386.1\|WP_023611962.1\|825471_826602_+\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_LS483386.1\|WP_172452905.1\|831808_833107_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|237171
NZ_LS483386.1\|WP_011054410.1\|822278_823235_+\|YbbR-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|227193
NZ_LS483386.1\|WP_023079409.1\|837814_839464_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NZ_LS483386.1\|WP_011106808.1\|823288_824644_+\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NZ_LS483386.1\|WP_002984858.1\|821430_822282_+\|TIGR00159-family-protein	unknown	unknown	gnl\|CDD\|224539
NZ_LS483386.1\|WP_002984845.1\|835537_836029_+\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|225976
NZ_LS483386.1\|WP_023612042.1\|828127_828760_+\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
NZ_LS483386.1\|WP_002984836.1\|839467_840256_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|227095
NZ_LS483386.1\|WP_023611966.1\|833292_833730_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_LS483386.1\|WP_002989931.1\|836851_837679_+\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	unknown	unknown	gnl\|CDD\|226239
NZ_LS483386.1\|WP_002984844.1\|836045_836855_+\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226238
NZ_LS483386.1\|WP_023080006.1\|824767_825409_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483386.1\|WP_020905130.1\|819189_819981_-\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974

Protein	Function_ID	Function_description	E-value
NZ_LS483386.1\|WP_050336191.1\|826611_827364_+\|acyl-[acyl-carrier-protein]-thioesterase	gnl\|CDD\|226401	COG3884, FatA, Acyl-ACP thioesterase [Lipid metabolism].	9.74349e-109
NZ_LS483386.1\|WP_023611114.1\|819980_821324_-\|Mur-ligase-family-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	1.97423e-110
NZ_LS483386.1\|WP_011054410.1\|822278_823235_+\|YbbR-like-domain-containing-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	1.65904e-113
NZ_LS483386.1\|WP_023611142.1\|827363_828128_+\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	6.49715e-128
NZ_LS483386.1\|WP_023612035.1\|833859_834879_+\|YeiH-family-putative-sulfate-export-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	6.6919e-100
NZ_LS483386.1\|WP_002989935.1\|835085_835511_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	3.64459e-31
NZ_LS483386.1\|WP_011106808.1\|823288_824644_+\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_LS483386.1\|WP_172452905.1\|831808_833107_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	1.08179e-11
NZ_LS483386.1\|WP_023612009.1\|829789_831622_+\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_LS483386.1\|WP_023079409.1\|837814_839464_+\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	1.69316e-77
NZ_LS483386.1\|WP_023612042.1\|828127_828760_+\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	2.38885e-87
NZ_LS483386.1\|WP_023611962.1\|825471_826602_+\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_LS483386.1\|WP_002984858.1\|821430_822282_+\|TIGR00159-family-protein	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	2.09715e-101
NZ_LS483386.1\|WP_002984845.1\|835537_836029_+\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	gnl\|CDD\|225976	COG3444, COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB [Carbohydrate transport and metabolism].	2.00329e-54
NZ_LS483386.1\|WP_020905130.1\|819189_819981_-\|type-1-glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	6.74846e-142
NZ_LS483386.1\|WP_002984836.1\|839467_840256_+\|response-regulator-transcription-factor	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	5.79862e-82
NZ_LS483386.1\|WP_023611966.1\|833292_833730_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	2.35343e-84
NZ_LS483386.1\|WP_002989931.1\|836851_837679_+\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	gnl\|CDD\|226239	COG3716, ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism].	1.55707e-109
NZ_LS483386.1\|WP_002984844.1\|836045_836855_+\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	gnl\|CDD\|226238	COG3715, ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism].	3.81104e-76

>NZ_LS483386.1|WP_023612042.1|828127_828760_+|TIGR01906-family-membrane-protein
MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVFMSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLLYPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHKVLFVGDSSWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARRQRLNVE
>NZ_LS483386.1|WP_023611142.1|827363_828128_+|TIGR01457-family-HAD-type-hydrolase
MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNNTTRTPEMVQSMLAKQFHVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIAAAGYVEELENPAYVVVGLDSQVTYEMLAIATLAIQKGALFIGTNPDLNIPTERGLMPGAGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQNDIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL
>NZ_LS483386.1|WP_050336191.1|826611_827364_+|acyl-[acyl-carrier-protein]-thioesterase
MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGRSNNNILVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGCLLVDILSYFALLNPDTRKVATIPEDLVAPFKTDFVKKLHRVPKMPLLEQSIDRDYYVRYFDIDMNGHVNNSKYLDWMYDVLGCAFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQLTSYHQITSDGQLNAQAMIEWRAIKQTESETD
>NZ_LS483386.1|WP_023611962.1|825471_826602_+|oxygen-independent-coproporphyrinogen-III-oxidase
MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQEFYSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPEKIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKTAGFHNISIDLIYALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQNRVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGVSFEERYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD
>NZ_LS483386.1|WP_023080006.1|824767_825409_+|hypothetical-protein
MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTPKQDIQKRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAVNEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLADMQEKLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSKP
>NZ_LS483386.1|WP_011106808.1|823288_824644_+|phosphoglucosamine-mutase
MGKYFGTDGVRGEANVELTPELAFQLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKERAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN
>NZ_LS483386.1|WP_011054410.1|822278_823235_+|YbbR-like-domain-containing-protein
MKRFLNSRPWLGMVSVFFAILLFLTAASSNHNNSSSQIYSPIETYTHSLKDVPIDMKYDSDKYFISGYSYGAEVYLTSTNRIKLDSEVNNDTRNFKIVADLTHSHPGTVNVNLRVENLPSGVTATVSPDKISVTIGKKESKVFPVRGSVDAKQIANGYEISKIETGVDKVEVTSDESTIALIDHVVAKLPDDQVLDRNYSSRVTLQAVSADGTILASAIDPAKTNLSVAVKKITKSVPIRVEAVGMMDDSLSDIQYKLSKQTAVISGSREVLEDIDEIIAEVNISDVTKNTSKTVSLSSSQVSIEPSVVTVQLTTTKK
>NZ_LS483386.1|WP_002984858.1|821430_822282_+|TIGR00159-family-protein
MNNLSSIDIKFLLSLFADPWLLAVHLLDILIVAYLIYRFIKALTGTKIMSLVQGVIFFLVLRFIAEWIGFTTITYLMNQVITYGVIAGVVIFTPEIRAGLEKFGRSTQVFLQKQYVSSESALVDALIKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPLNADISSQLLINIFIPNTPLHDGAVIVGQNKIVAACAYLPLSESKAISKEFGTRHRAAIGLSENSDALTIIVSEETGAISVTRKGQFLHDLSTDEFETVLRTYLMSDSNVTLPWYKKILGGKSK
>NZ_LS483386.1|WP_023611114.1|819980_821324_-|Mur-ligase-family-protein
MKMKTLLGIIAGKAAQSILTKLGRGSTYPGRLALACNKDILKDLSKDYDIVVVTGTNGKTLTTALTVGILKEAFGEIITNPSGANMITGITSTFLAAKKGKSGRQIAVLEIDEASLPRITTYLKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGARNAPKATILANGDSPIFSSKDIVNPVQYYGFDTAKHAPQLAHYNTEGILCPKCEHILQYRLNTYANLGDFICLNCGFKRPQLDYRLTELTTITNHSSEFIIDGQDYKINVGGLYNIYNALAAVSVAEFFGVSPEKIKAGFNKSKAVFGRQETFTIGDKSCTLILIKNPVGASQALEMIQLADYPFSLSVLLNANYADGIDTSWIWDANFELITQMPITEINAGGVRHSEIARRLRVTGFDDTKIKQAEKLEQIIETIEKQEAKHAYILATYTAMLEFRSLLADRHVVEKEMI
>NZ_LS483386.1|WP_020905130.1|819189_819981_-|type-1-glutamine-amidotransferase
MTYTSLKSPENQDYIYDLTIAHLYGNLMNTYGDNGNILMLKYVAEKLGARVTVDIVSINDTFEQDDYDIVFFGGGQDYEQSIVAKDLPSKKAALADYIANNKVVLAICGGFQLLGQYYVQANGVKIDGLGIMGHYTLNQHQNRFIGDIKIHNDEFNETYYGFENHQGRTFLSGDEKPLGRVVYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVNLAYRLVTTALKKKYGSAISLSSYDDILKQEITEEYADLKSKASFNKV
>NZ_LS483386.1|WP_023612009.1|829789_831622_+|elongation-factor-4
MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDTSEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDTKK
>NZ_LS483386.1|WP_172452905.1|831808_833107_+|LPXTG-cell-wall-anchor-domain-containing-protein
MNKTKQNKTKQNKTKQNKTKQNKTKHSLLCRYGLTSAAALLLTFGGASAVKANEQSNIGALQSQLQDLRENLPKVGDNIPDYNVLRKHEFYQHLQKFEDQLNLYLKVLDQNLSQLQGPRGDKGETGEQGPRGAQGPAGPQGPVGPAGKDGTQGPRGDKGETGEQGPRGAQGPAGPAGKDGTQGPRGDKGETGEQGPRGAQGPAGPQGPMGPAGERGEKGEPGTQGAKGDRGETGPAGPVGPRGDKGETGAKGEQGPAGKDGKAGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGKDGKDGQPGKPAPKTPEVPQKPGTAPHTPKTPQIPGQSKDVTPAPQNPSNRGLNKPQTQGGNQLAKTPAAHDTHRQLPATGETTNPFFTAAAVAIMTTAGVVAVAKRQENN
>NZ_LS483386.1|WP_023611966.1|833292_833730_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
METSDELKQRIGDLSYEVTQHAATESPFTGKYDDFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRIEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET
>NZ_LS483386.1|WP_023612035.1|833859_834879_+|YeiH-family-putative-sulfate-export-transporter
MSTHLRKLPGLLLCLLLALSAWYLGRLFPIIGAPVFAILLGMLLALFYEHGDKTKEGISFTSKCILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALLVAYGSQKWLRLDVNTATLVGIGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNMLAALLFPSLGQLIGLSNEGFATFAGTAVNDTSSVTATATAWDAIHHSNTLDGATIVKLTRTLAILPITLGLSLYQAKKEHDIVTEEGFSLRKSFPRFILFFLLASLITTLMTSLGVSADSFHSLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQLSLGIW
>NZ_LS483386.1|WP_002989935.1|835085_835511_+|PTS-sugar-transporter-subunit-IIA
MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYTSQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLVFLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD
>NZ_LS483386.1|WP_002984845.1|835537_836029_+|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB
MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQMTLKMAVPNGMKLLIRSVEDSIKLFNDPRAKDKRIFVIVNSVKDACAIAKEVPDLEAVNVANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQLVN
>NZ_LS483386.1|WP_002984844.1|836045_836855_+|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC
MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDMKVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGMLAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILVGSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYLKLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA
>NZ_LS483386.1|WP_002989931.1|836851_837679_+|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID
MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTLLPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAITAVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHYYSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKGAKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC
>NZ_LS483386.1|WP_023079409.1|837814_839464_+|sensor-histidine-kinase
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRYHRLISKQEALLDELGKNSLLPFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPSQGLLFASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGHYLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLAVPKLFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE
>NZ_LS483386.1|WP_002984836.1|839467_840256_+|response-regulator-transcription-factor
MYKLVIIEDEHIIRKWLRYAIDYKALDILVIGEAKDGKEGAVLIKESQPDIVLTDINMPIMTAFDMFEATKDQTYAKIILSGYADFPNARSAIHYGVLEFLTKPIEKAALWECLQTIIAKIEKQKGSNQKTDACVYIPLPQMTDQIPEVVKDILEWVHAHFQDKISTSRLAHDLGYSESYIYQNIKKHLQMPLSDYINQYRINQAIQLMQQEPDLMVYEIAQAVGIYDYRYFDRVFKKYLGQTVKAFKEEHFMKDTDRSKPC

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Crispr_ID: NZ_LS483386_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483386_2

1322716-1322809

Unclear

Consensus_repeat	Method
AATCCACTCACCCGTGAAGGGTGAGAC	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NZ_LS483386_2

>merge|NZ_LS483386|2|1322716-1322809|CRISPRCasFinder
AATCCACTCACCCGTGAAGGGTGAGACCTAGTGGCTATGCGGAGTTACTTATCCAACTGATTATTTTAATCCACTCACCCGTGAAGGGTGAGAC

>NZ_LS483386|2|1|1322716-1322809|CRISPRCasFinder
AATCCACTCACCCGTGAAGGGTGAGAC	CTAGTGGCTATGCGGAGTTACTTATCCAACTGATTATTTT
AATCCACTCACCCGTGAAGGGTGAGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483386.1\|WP_023612523.1\|1319671_1320382_-\|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2	unknown	unknown	gnl\|CDD\|223856
NZ_LS483386.1\|WP_023612499.1\|1315328_1317062_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NZ_LS483386.1\|WP_050336302.1\|1323159_1324407_-\|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_LS483386.1\|WP_023612521.1\|1317886_1318993_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|184456
NZ_LS483386.1\|WP_023612512.1\|1319035_1319659_-\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
NZ_LS483386.1\|WP_023612491.1\|1311984_1312665_-\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NZ_LS483386.1\|WP_011018021.1\|1320602_1321535_-\|magnesium-transporter-CorA-family-protein	unknown	unknown	gnl\|CDD\|213361
NZ_LS483386.1\|WP_000702264.1\|1332589_1333147_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483386.1\|WP_023612518.1\|1324560_1327209_-\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_LS483386.1\|WP_002983781.1\|1317058_1317799_-\|response-regulator	unknown	unknown	gnl\|CDD\|227095
NZ_LS483386.1\|WP_011284995.1\|1331803_1332565_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|273478
NZ_LS483386.1\|WP_023612519.1\|1314176_1315256_-\|MmcQ/YjbR-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|225197
NZ_LS483386.1\|WP_001188029.1\|1330540_1330867_-\|DUF771-domain-containing-protein	unknown	unknown	gnl\|CDD\|368511
NZ_LS483386.1\|WP_023612487.1\|1321626_1322586_-\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_LS483386.1\|WP_023612502.1\|1328374_1328770_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|181104
NZ_LS483386.1\|WP_002983750.1\|1328787_1329042_-\|DUF1912-family-protein	unknown	unknown	gnl\|CDD\|286073
NZ_LS483386.1\|WP_021340693.1\|1333146_1334499_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|380090
NZ_LS483386.1\|WP_011284992.1\|1329354_1330491_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271189
NZ_LS483386.1\|WP_002989056.1\|1312806_1313280_+\|arginine-repressor	unknown	unknown	gnl\|CDD\|224355
NZ_LS483386.1\|WP_011888719.1\|1327210_1327774_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379082

Protein	Function_ID	Function_description	E-value
NZ_LS483386.1\|WP_023612523.1\|1319671_1320382_-\|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2	gnl\|CDD\|223856	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones].	6.4437e-43
NZ_LS483386.1\|WP_023612499.1\|1315328_1317062_-\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	2.08305e-64
NZ_LS483386.1\|WP_050336302.1\|1323159_1324407_-\|CRISPR-associated-endonuclease-Cas3''	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	5.35517e-59
NZ_LS483386.1\|WP_023612521.1\|1317886_1318993_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|184456	PRK14018, PRK14018, bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB.	2.3863e-163
NZ_LS483386.1\|WP_023612512.1\|1319035_1319659_-\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.7195e-35
NZ_LS483386.1\|WP_023612491.1\|1311984_1312665_-\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	3.96742e-40
NZ_LS483386.1\|WP_011018021.1\|1320602_1321535_-\|magnesium-transporter-CorA-family-protein	gnl\|CDD\|213361	cd12827, EcCorA_ZntB-like_u2, uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family. A uncharacterized subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB (EcCorA-ZntB_like) family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes.The EcCorA-ZntB-like family includes the Mg2+ transporters Escherichia coli and Salmonella typhimurium CorAs, which can also transport Co2+, and Ni2+. Structures of the intracellular domain of EcCorA-ZntB-like family members, Vibrio parahaemolyticus and Salmonella typhimurium ZntB, form funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport through Salmonella typhimurium CorA. Natural variants such as GVN and GIN, such as occur in some ZntB family proteins, may be associated with the transport of different divalent cations, such as zinc and cadmium. The functional diversity of MIT transporters may also be due to minor structural differences regulating gating, substrate selection, and transport.	1.35313e-79
NZ_LS483386.1\|WP_023612518.1\|1324560_1327209_-\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_LS483386.1\|WP_002983781.1\|1317058_1317799_-\|response-regulator	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	1.85886e-83
NZ_LS483386.1\|WP_011284995.1\|1331803_1332565_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	0.00224312
NZ_LS483386.1\|WP_023612519.1\|1314176_1315256_-\|MmcQ/YjbR-family-DNA-binding-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	2.00918e-35
NZ_LS483386.1\|WP_001188029.1\|1330540_1330867_-\|DUF771-domain-containing-protein	gnl\|CDD\|368511	pfam05595, DUF771, Domain of unknown function (DUF771). Family of uncharacterized ORFs found in Bacteriophage and Lactococcus lactis.	6.85209e-27
NZ_LS483386.1\|WP_023612487.1\|1321626_1322586_-\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	4.87701e-56
NZ_LS483386.1\|WP_023612502.1\|1328374_1328770_-\|hypothetical-protein	gnl\|CDD\|181104	PRK07758, PRK07758, hypothetical protein; Provisional.	0.000143012
NZ_LS483386.1\|WP_002983750.1\|1328787_1329042_-\|DUF1912-family-protein	gnl\|CDD\|286073	pfam08930, DUF1912, Domain of unknown function (DUF1912). This domain has no known function. It is found in various Streptococcal proteins.	3.74168e-47
NZ_LS483386.1\|WP_021340693.1\|1333146_1334499_-\|CHAP-domain-containing-protein	gnl\|CDD\|380090	pfam18013, Phage_lysozyme2, Phage tail lysozyme. This domain has a lysozyme like fold. It is found in the tail protein of various phages probably giving them the ability to degrade the host cell wall peptidoglycan layer.	4.59307e-16
NZ_LS483386.1\|WP_011284992.1\|1329354_1330491_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	3.21501e-33
NZ_LS483386.1\|WP_002989056.1\|1312806_1313280_+\|arginine-repressor	gnl\|CDD\|224355	COG1438, ArgR, Arginine repressor [Transcription].	2.68589e-66
NZ_LS483386.1\|WP_011888719.1\|1327210_1327774_-\|AAA-family-ATPase	gnl\|CDD\|379082	pfam13238, AAA_18, AAA domain.	0.00452424

>NZ_LS483386.1|WP_023612487.1|1321626_1322586_-|Gfo/Idh/MocA-family-oxidoreductase
MAKVRYGIVSTAQVAPRFIEGVRLAGNGEVVAVSSRSLDKAKAFAAAHQLPKAYGSLDDMLLDASIDAIYVASINQDHFPAAKKALLAGKHVLVEKPFTLTAAQAEELFALAQERGLFLMEAQKAVFIPMTQRLKGLIAAVELGDIVSVSSTTAYPNIDHVTWFRDLEKGGGTVHFMAPYALSYLPYLFDADIVSASGVAHFPKGQSDSQSKLVLTLSNGVLVDIFLTTHLSLPHELVIYGTKGRLEIPHFWKNTHATLVRPDGSRSVIEAIMSSDFEAEAHHVSQMILEGQLTSPVMTKSLTLSGVGLIEKLYRSWGK
>NZ_LS483386.1|WP_011018021.1|1320602_1321535_-|magnesium-transporter-CorA-family-protein
MPTLPKASSAITLINLDQLTEHDQEALVSEGLIDAEVFDYAKDKNETSFMEENKEKLTIVFQILDRQEEAYHPNYIPRVIPITLFLNDQSLYILGHDHSLTLIEEVFPDLDESRSPRHLVFQLLTAFTKQYVPLMDEIAQQRDKLIEALRQKANKTNLESLANLQSGTVYILMGSKQNEQMLAELKDMPGQQDLEEDEAEQLRDAIIEARQLSNMCDLNTRVLKEISSSYNNVLSNNLNNNVTSLTIFSIGISIIAMVTSFYGMNVKLPFAKVDSVWFWIVLTTSLVALLIMVVMYWYVHKRNRNASKRI
>NZ_LS483386.1|WP_023612523.1|1319671_1320382_-|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2
MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTITIFDKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGIHQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVASGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHILLLKKVGGVLIIVMGILLMTGTLNNLAQLFG
>NZ_LS483386.1|WP_023612512.1|1319035_1319659_-|TlpA-family-protein-disulfide-reductase
MKKGLLVTTGLACLGLLTACSTQDNMAKKEITQDKMSMAAKKKDKMSTSKDKSMMTDKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASWCSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFKKWFQGTDYKDLPVLLDPDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH
>NZ_LS483386.1|WP_023612521.1|1317886_1318993_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKKVKSTKVDPNAPVDQKMIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIHQTGHAETVEVTYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADLAIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPVIDESKYPKPSATEIKAKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLFSSKDKFESGCGWPSFSRPISPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKDQGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE
>NZ_LS483386.1|WP_002983781.1|1317058_1317799_-|response-regulator
MYSLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPKLNGIQLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKADVEDMLGKLRKKLELSKKTETIQELVEQPQKEVSAIAMAIHERLADSDLTLKSLAQQLGFSPNYLSVLIKKDLGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVGFEDMNYFSQRFKQLVGVTPSQYKKGGQA
>NZ_LS483386.1|WP_023612499.1|1315328_1317062_-|sensor-histidine-kinase
MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERDTRQSIRQSSQFIDAYIKPLKETTSVLAKNTEIQAFASQIHQENDKQVLQLMKMVLATNSDLQAAVLVTKDGRTVSTNSQLTMKTSSDMMAEPWYKAAIDRQAMPVLTPARQLSLSSKKEWVVSVTQEVVDRAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVYHPKKSVYSSSKEMAAMKPYLAIQNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRVQRQIFWSFLGTGLLACLICGFATVLALRRWIRPIQQLQQVILAIQKGDRQLRAQETGSPELTDLAQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKRVVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYEVQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSDTAQHLVLTVWDNGKGIEDSSLTNSQSLLTRGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQLSLPKMHELMADDTQENE
>NZ_LS483386.1|WP_023612519.1|1314176_1315256_-|MmcQ/YjbR-family-DNA-binding-protein
MSLASDYFSRQTPIVEKLMAYGFEKRNNGYFYNERFMEEEFEAQLRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLERLSVACFEVTPFQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVGGKWYAMIFSLLADKLDQIPERLVGQTCEVMTVKVNPKDFPQLLQQEGIYPAYHMSKKNWISIILDDKVTDDKLWTLVTQSRQLVNPNGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYITAPVKSIRYVCQVLETDIPNEGYRKNPNIDKLMRLRKCQQYEDGLLSFDLMKEHGVAAVRGPRRLSPQLIAFLKEKEYFKENN
>NZ_LS483386.1|WP_002989056.1|1312806_1313280_+|arginine-repressor
MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSRDMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGLAQSFGSILDAMQIPEIVATVCGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK
>NZ_LS483386.1|WP_023612491.1|1311984_1312665_-|Crp/Fnr-family-transcriptional-regulator
MIRREDYQYLRKLNDFRYFSIEQFDKIVGQMEFRKAKKDHILFFEGDKRDKLFLVISGYFKVEQSDQSGTFMYTDFIRHGTIFPYGGLFTDDYYHFSVVAMTDVTYFYFPVDLFEDYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQSLAILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRDLKKQELITIKGKYLTYLDKDYFLQYTK
>NZ_LS483386.1|WP_050336302.1|1323159_1324407_-|CRISPR-associated-endonuclease-Cas3''
MRMILAHYDCKKDKKQSLDEHLWHVACSSRQEASIIGQGDVLFLIGLYHDLGKADRTFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMTFNEIVGYVISAHHGMYDLCYYFDDAEYYGFNKFKNRINRDLDGYHYHEDIKGYALKLEKKLCDYGYKDLRELIDKAFDNYQQAMSSLNWQDKSEWDYYQSCMVRLYLSLLKNADILDTVNAYGLKISPMDKTERSFLKHSYLAAIEQKYASFGQPNNQLNTIRTEIAERVKERGKRDSKGIYRLDLPTGAGKTNLSMRYAFHQLVHHDKSRFFYITPFLSVLEQNASEIRKVTGDLGVLEHHSNVVKQVNEDDDDKDSLLSAYLSDSWDSQVVLTSMVQFFQTLFKTKSANLRRFSSLIKVDKRLFEFFIVAFNC
>NZ_LS483386.1|WP_023612518.1|1324560_1327209_-|valine--tRNA-ligase
MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGISRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFVDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATTRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIVNKLIPIVGDEHADPEFGTGVVKITPAHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVNIEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDNRVDFYPPRFNDTFLQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSALWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDASWNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVTENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKILRLLHPIMPFVTEEIYAQYAQGSIVTVDYPVVRPAFENEAAHKGVESLKDLIRAVRNARAEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSIITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVVQKEKDKQADYQAKYDATQERIAEMKKIKS
>NZ_LS483386.1|WP_011888719.1|1327210_1327774_-|AAA-family-ATPase
MNLIIIGAQASGKMTIGQEVARQTGMTLFHNHDSIDFVLRFMPWSQESTALIERIRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVLFVELKTDIEERLKRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTHYQKINNTHLTAAETAQLIIQKMTHIKEN
>NZ_LS483386.1|WP_023612502.1|1328374_1328770_-|hypothetical-protein
MAKQKNRKKALKLEMKRNGLLKKAGQVFDKAVESVETAVDKTISAGKNLVEKDSQTVENLTASKERLTLDEFAGQPVVAGIRSDLVETLYAEGIHSAQAFKEWTEKDLLALKGIGPATVKKLVENGASFKK
>NZ_LS483386.1|WP_002983750.1|1328787_1329042_-|DUF1912-family-protein
MSYEKEFLKDFEDWVKTQIQVNQLAMATSQEVAQEDGDERAKDAFIRYESKLDAYEFLLGKFDNYKNGKAFHDIPDELFGARHY
>NZ_LS483386.1|WP_011284992.1|1329354_1330491_-|tyrosine-type-recombinase/integrase
MATYRQRGKKKLWDYRVYGKDGKLIASGSGFRTKKEASYEALKIEQKKYYSDVINSNATLFEMWQIWYDLVVEPSELDILTKQKYQARGKIIEKYLSDIPANRIKHSKYQEFIKFYGKNVTLNLMTCLNSDIRKVIIFFKRDGVLIEDFTEGVKIFGKPYRKSPEDKYLKSIEDYQKLLAYLKRIANYSDSIIPFFLFTMLQTGFRFGEAMAITWDDIDFERNSIYTYRRYSSIKKDFTKPKTRTSIRRVPVSHDLKELLLELKFQQERMLRGLHIKNTDQLIFYDYRFGMISNNAVNKFLASSLEKLEIESKMSSTGARHTYGSYLLANGVDIWAVAKLMGHKDIKQLIETYGHLLLEVEEKENDQLLKILNNKGSF
>NZ_LS483386.1|WP_001188029.1|1330540_1330867_-|DUF771-domain-containing-protein
MQQVFNVSVPVPDDVVIISKEEYLDLLSDNEQGKWWDIDNLQELLGLGRSKLINDILLNPDIKKEVDLSINPNGFIVYPRGKGSRYKILATRARKYFEENFGSILLNN
>NZ_LS483386.1|WP_011284995.1|1331803_1332565_-|LPXTG-cell-wall-anchor-domain-containing-protein
MTKEKMMSFMTIASIALLGSGVVCANDVADPVAGTTDAVVVPVSPQPTTPIEHTGTDTTNKIVDSTKPSEDKVADSTDQLIPPVKSDLETSEDKVTDPTETKPSKEKTEEPVKSNDSEVIPEQPKSEEVKKAEENTGASTTETPKPVTKPVIETPIVTNTGYTVLGTQDGNVWVQTETGNVLKPAIAIGAVKQKDGTVALKTRDGKLEVLPSTGETKTILAILGGLAILGAIWVGWKENIKKYLTFLKKKSKK
>NZ_LS483386.1|WP_000702264.1|1332589_1333147_-|hypothetical-protein
MKIRKVIIVMLAVALSLGFYRLYHRQKPSQLIEANQEILVKPITPNKSKIKVKRNVAKEAKATLEMPEERVNEKEAKQVKSAIVIPIDYLASISSQDDIKVTYDNKLSITNPAMAASIKTMLLAGYHFDLDSLTVYQSNSDNVYQFTILLVTHQQDQLSLVGNYVTGTGQFEFVSLHGTPKNVMF
>NZ_LS483386.1|WP_021340693.1|1333146_1334499_-|CHAP-domain-containing-protein
MSIPFFIVVIVTIIFSSSQGDCQVTPDLSTQFVTSSDSASQTDWTKKGSIANVTAGKVFHAWVSKGLSGASAAGIVGWVNSEGGFAMIGRAEGHYGNDLRTNSIAFGVKPIGLSYYTTEAGGGIYQFTPYTKYAPLGDPKWENADAMNEFVAKAILAGDWNASMDLTGGNHTFKQMAQMTDPKQATLVWQAYERGSTAHINPFQKQADAQKAYELFGGVKYSYNEIVFHKSFDIFGPLKPGEGESKEVVLSLCESGSYSKGAFGKDRTGKVNYTSYNAWRPEQLPADLKPYALDPRSVGLNYRQAVGWYAIASTGGQCTDLSASLMYALWSKNGSHPTQKAGNGNMVVANWVRTFGGSSDKSPTSGAVFSSAGTSSAGHTGVVSHVFENGDILIVEQNYASYSGDDGGFGKYSWNYRYVTTAELKNEGYTFYNPAKLGYQIMKSVGTVGK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LS483386_2	2.1\|1322743\|40\|NZ_LS483386\|CRISPRCasFinder	1322743-1322782	40	MK448679	Streptococcus phage Javan137, complete genome	35066-35105	8	0.8
NZ_LS483386_2	2.1\|1322743\|40\|NZ_LS483386\|CRISPRCasFinder	1322743-1322782	40	MK448950	Streptococcus phage Javan464, complete genome	37224-37263	9	0.775

1. spacer 2.1|1322743|40|NZ_LS483386|CRISPRCasFinder matches to MK448679 (Streptococcus phage Javan137, complete genome) position: , mismatch: 8, identity: 0.8

ctagtggctatgcggagttacttatccaactgattatttt	CRISPR spacer
ctagtggctatgcggagttacttatccaaattatcgagga	Protospacer
***************************** * **..

2. spacer 2.1|1322743|40|NZ_LS483386|CRISPRCasFinder matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 9, identity: 0.775

ctagtggctatgcggagttacttatccaactgattatttt	CRISPR spacer
cgagtggctatgcggagttgcttatccaactaatcgagga	Protospacer
* *****************.***********.**..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

36638 : 48950

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023612102.1\|36638_40364_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	2.1e-40	26.8
WP_023612105.1\|40524_41979_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	6.3e-54	33.3
WP_023612098.1\|42006_43029_+	phosphoribosylformylglycinamidine cyclo-ligase	R9TMC7	Synechococcus_phage	4.0e-63	41.5
WP_002986700.1\|43196_43751_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.4e-25	36.1
WP_023612109.1\|43934_45482_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	4.4e-45	52.4
WP_010921776.1\|45538_46663_-	SH3 domain-containing protein	F8HGP2	Streptococcus_phage	7.7e-07	28.6
WP_023612108.1\|46915_48181_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_023612097.1\|48458_48950_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.8e-19	43.1

DBSCAN-SWA_2

346398 : 352433

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002990917.1\|346398_347034_+	dTMP kinase	M1PSC7	Streptococcus_phage	2.7e-65	63.4
WP_002985844.1\|347051_347927_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.1e-68	46.6
WP_002985838.1\|348589_348913_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.3e-28	59.4
WP_021733048.1\|348917_349781_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	3.8e-115	74.7
WP_002985833.1\|349807_350200_+	hypothetical protein	NA	NA	NA	NA
WP_009880724.1\|350246_350876_-	copper homeostasis protein CutC	NA	NA	NA	NA
WP_011284536.1\|351175_351532_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	6.3e-40	65.8
WP_023078944.1\|351605_352433_-	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	3.8e-128	79.5

DBSCAN-SWA_3

537419 : 602083

Temperate_phage(49.09%)

holin,tail,capsid,integrase,portal,tRNA,terminase

attL 534102:534119|attR 616378:616395

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
534102:534119	attL	NA	NA	NA	NA
WP_002985437.1\|537419_538766_+\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.1e-55	30.8
WP_023612366.1\|539180_540071_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	8.8e-06	29.8
WP_023612323.1\|540067_541045_+	YvcK family protein	A1IMD5	Streptococcus_phage	6.6e-140	74.8
WP_023612370.1\|541041_541953_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	3.8e-105	64.6
WP_023612367.1\|542084_543482_+	C69 family dipeptidase	NA	NA	NA	NA
WP_023612329.1\|543633_545181_+	zinc ABC transporter substrate-binding protein AdcA	NA	NA	NA	NA
WP_023612369.1\|545327_546050_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_023612346.1\|546068_547268_+	SIS domain-containing protein	NA	NA	NA	NA
WP_002985307.1\|547364_547625_-	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_002985305.1\|547739_548681_-	bifunctional oligoribonuclease/PAP phosphatase NrnA	NA	NA	NA	NA
WP_002985303.1\|549074_549524_+	flavodoxin	NA	NA	NA	NA
WP_002994052.1\|549698_549983_+	chorismate mutase	NA	NA	NA	NA
WP_050336105.1\|549975_551238_+	chloride channel protein	A0A1X9I5Z9	Streptococcus_phage	6.4e-95	51.3
WP_002985298.1\|551352_551700_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_023612372.1\|552062_553139_-\|integrase	site-specific integrase	Q0R5B4	Streptococcus_phage	7.5e-68	41.2
WP_023612337.1\|553257_553779_-	hypothetical protein	Q938N8	Temperate_phage	7.5e-66	97.7
WP_023612306.1\|553789_554167_-	ImmA/IrrE family metallo-endopeptidase	A0A1P8VVK5	Streptococcus_phage	8.1e-54	76.8
WP_023611288.1\|554150_554510_-	helix-turn-helix transcriptional regulator	A0A1P8VVN3	Streptococcus_phage	1.7e-56	95.0
WP_023612341.1\|554697_554916_+	helix-turn-helix transcriptional regulator	A0A1P8VVR5	Streptococcus_phage	5.9e-33	97.2
WP_023612302.1\|555015_555246_+	hypothetical protein	NA	NA	NA	NA
WP_023612348.1\|555382_555601_+	hypothetical protein	NA	NA	NA	NA
WP_003056170.1\|555602_555845_+	hypothetical protein	NA	NA	NA	NA
WP_023612340.1\|555831_557148_+	AAA family ATPase	A0A097BY67	Enterococcus_phage	7.8e-152	63.8
WP_003056188.1\|557162_558245_+	AAA family ATPase	A0A0K2CZH1	Paenibacillus_phage	2.5e-103	53.3
WP_003056185.1\|558439_559033_+	hypothetical protein	A0A097BY29	Enterococcus_phage	1.7e-29	43.5
WP_080262841.1\|559032_560616_+	DEAD/DEAH box helicase	A0A097BY72	Enterococcus_phage	2.0e-234	77.8
WP_023612331.1\|560628_560823_+	hypothetical protein	NA	NA	NA	NA
WP_003059078.1\|563379_563562_+	hypothetical protein	NA	NA	NA	NA
WP_023612320.1\|563554_563950_+	RusA family crossover junction endodeoxyribonuclease	Q5YA86	Bacillus_phage	1.8e-40	58.8
WP_023612313.1\|563946_564171_+	hypothetical protein	NA	NA	NA	NA
WP_023612326.1\|564173_564359_+	hypothetical protein	A3F626	Streptococcus_phage	6.6e-09	82.9
WP_023612315.1\|564355_564607_+	hypothetical protein	NA	NA	NA	NA
WP_023612304.1\|564590_564995_+	hypothetical protein	A3F627	Streptococcus_phage	1.6e-39	65.2
WP_014411870.1\|564991_565276_+	hypothetical protein	A0A097PAV1	Streptococcus_pyogenes_phage	1.4e-37	89.4
WP_011018133.1\|565277_565910_+	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	2.3e-85	68.6
WP_014411869.1\|565912_566623_+	DUF1642 domain-containing protein	Q938L9	Temperate_phage	3.0e-25	46.2
WP_014411868.1\|566619_566991_+	hypothetical protein	NA	NA	NA	NA
WP_021340586.1\|567258_567696_+	DUF1492 domain-containing protein	A0A097PBF1	Streptococcus_pyogenes_phage	1.4e-76	99.3
WP_011054748.1\|568214_568472_-	hypothetical protein	NA	NA	NA	NA
WP_002986854.1\|568552_569071_+	ParB N-terminal domain-containing protein	Q938L7	Temperate_phage	1.5e-90	100.0
WP_111711133.1\|569049_569727_+	hypothetical protein	Q938L6	Temperate_phage	4.3e-130	99.6
WP_002986845.1\|569849_570119_+	hypothetical protein	B5SP24	Lactococcus_phage	2.8e-16	51.1
WP_002986841.1\|570179_570557_+	ASCH domain-containing protein	Q938L5	Temperate_phage	1.7e-67	100.0
WP_023612332.1\|570607_571081_+	hypothetical protein	Q938L4	Temperate_phage	7.3e-76	98.7
WP_010922074.1\|571163_572375_+\|terminase	PBSX family phage terminase large subunit	Q938L3	Temperate_phage	3.7e-225	99.7
WP_002986832.1\|572388_573891_+\|portal	phage portal protein	Q938L2	Temperate_phage	5.4e-282	100.0
WP_011054746.1\|573895_575374_+\|capsid	phage minor capsid protein	Q938L1	Temperate_phage	8.2e-275	100.0
WP_002986829.1\|575345_575585_+	hypothetical protein	Q938L0	Temperate_phage	2.8e-36	100.0
WP_011054745.1\|575646_575913_+	hypothetical protein	Q938K9	Temperate_phage	1.5e-38	100.0
WP_011106689.1\|576038_576653_+	hypothetical protein	Q938K8	Temperate_phage	1.3e-96	100.0
WP_010922080.1\|576656_577475_+\|capsid	N4-gp56 family major capsid protein	Q79S85	Temperate_phage	4.0e-146	100.0
WP_011054743.1\|577528_577945_+	hypothetical protein	Q938K7	Temperate_phage	1.1e-56	100.0
WP_010922082.1\|577934_578267_+	hypothetical protein	Q79S86	Temperate_phage	9.6e-59	100.0
WP_010922083.1\|578266_578623_+	hypothetical protein	Q79S88	Temperate_phage	4.5e-62	100.0
WP_010922084.1\|578619_579018_+\|capsid	phage capsid protein	Q79S87	Temperate_phage	3.5e-71	100.0
WP_011054741.1\|579017_579503_+	hypothetical protein	Q938K6	Temperate_phage	1.6e-86	100.0
WP_011054740.1\|579541_579976_+	hypothetical protein	Q938K5	Temperate_phage	2.6e-72	100.0
WP_011284973.1\|579979_580561_+	hypothetical protein	Q938K4	Temperate_phage	4.9e-106	99.5
WP_023612368.1\|580550_583811_+	tape measure protein	Q938K3	Temperate_phage	0.0e+00	99.5
WP_011054737.1\|583807_584524_+\|tail	phage tail family protein	Q938K2	Temperate_phage	2.9e-137	100.0
WP_111706021.1\|584520_586668_+\|tail	phage tail protein	Q938K1	Temperate_phage	0.0e+00	95.4
WP_011284843.1\|586664_587879_+	hypothetical protein	A3F657	Streptococcus_phage	5.0e-44	49.5
WP_011284842.1\|587865_588195_+	hypothetical protein	NA	NA	NA	NA
WP_023612347.1\|588205_590095_+	gp58-like family protein	Q938J9	Temperate_phage	1.8e-189	74.3
WP_002988448.1\|590106_590535_+	DUF1617 family protein	Q938J8	Temperate_phage	8.1e-58	84.3
WP_011054443.1\|590537_591170_+	hypothetical protein	Q938J7	Temperate_phage	2.0e-44	49.5
WP_011017397.1\|591181_591454_+	hypothetical protein	A7J2B2	Streptococcus_phage	5.5e-36	91.0
WP_011054444.1\|591450_591678_+\|holin	phage holin	A7J2B3	Streptococcus_phage	7.6e-31	98.7
WP_011054445.1\|591793_593002_+	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	2.9e-214	87.5
WP_050440680.1\|593111_594098_-	DNA/RNA non-specific endonuclease	A7J2B8	Streptococcus_phage	5.2e-169	99.7
WP_030127450.1\|594330_594510_+	hypothetical protein	A3F673	Streptococcus_phage	3.4e-18	77.6
WP_002985295.1\|595355_595925_+	hydrolase	NA	NA	NA	NA
WP_038431254.1\|595925_597878_+	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	1.2e-143	46.3
WP_023612353.1\|598234_599959_+	septation ring formation regulator EzrA	NA	NA	NA	NA
WP_020905037.1\|600090_600549_-	YueI family protein	W6LLD2	Streptococcus_phage	3.9e-18	39.1
WP_002985288.1\|600775_602083_+	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	1.2e-240	96.6
616378:616395	attR	NA	NA	NA	NA

DBSCAN-SWA_4

677679 : 688283

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044559748.1\|677679_679890_-	LTA synthase family protein	W6LM83	Streptococcus_phage	6.5e-268	68.9
WP_023612435.1\|679997_681161_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	3.4e-143	65.1
WP_002985140.1\|681157_681844_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.0e-88	68.9
WP_002990262.1\|681937_683104_+	chorismate synthase	A0A291AU41	Pandoravirus	4.5e-34	32.8
WP_002990260.1\|683164_683506_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	2.6e-19	41.1
WP_023612440.1\|683727_685080_+	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	5.9e-30	24.7
WP_002990257.1\|685167_686436_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_012560601.1\|686465_686906_-	hypothetical protein	NA	NA	NA	NA
WP_011184383.1\|687140_688283_+	cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	1.4e-24	27.3

DBSCAN-SWA_5

987986 : 1066953

Streptococcus_phage(58.73%)

terminase,tail,capsid,head,integrase,portal,tRNA,protease

attL 1021338:1021397|attR 1063492:1063587

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023612481.1\|987986_988871_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_023612473.1\|988986_990327_-	DUF2130 domain-containing protein	NA	NA	NA	NA
WP_023612470.1\|990423_991380_-	aromatic acid exporter family protein	NA	NA	NA	NA
WP_002993908.1\|991390_991987_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_023612475.1\|992078_994715_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_023612464.1\|994729_995431_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-36	37.0
WP_023612443.1\|995548_996091_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_002984480.1\|996233_996875_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_023612454.1\|997037_997526_-	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_023612456.1\|997536_997737_-	CsbD family protein	J7KJ36	Streptococcus_phage	1.8e-07	51.5
WP_002984475.1\|997777_998317_-	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_002984473.1\|998329_998518_-	DUF2273 domain-containing protein	NA	NA	NA	NA
WP_002984470.1\|998528_999140_-	alkaline shock response membrane anchor protein AmaP	NA	NA	NA	NA
WP_002984469.1\|999176_999425_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_023612212.1\|999787_1002106_-	DNA helicase PcrA	A7KV33	Bacillus_phage	2.3e-130	40.9
WP_023612223.1\|1002634_1003957_+	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_023612209.1\|1004076_1005312_+	cation diffusion facilitator family transporter	NA	NA	NA	NA
WP_023612220.1\|1005681_1006455_-	CAMP factor pore-forming toxin Cfa	NA	NA	NA	NA
WP_002989634.1\|1006823_1007660_-	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_023612213.1\|1007675_1008305_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.7e-27	35.5
WP_002992417.1\|1008314_1008956_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_002989626.1\|1009062_1009398_-	alkylphosphonate utilization protein	NA	NA	NA	NA
WP_023612218.1\|1009593_1011408_-	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	6.8e-98	38.6
WP_023612216.1\|1011583_1012141_-	signal peptidase I	NA	NA	NA	NA
WP_111711138.1\|1012358_1013861_-	pyruvate kinase	NA	NA	NA	NA
WP_002984444.1\|1013923_1014937_-	6-phosphofructokinase	NA	NA	NA	NA
WP_023612222.1\|1015016_1018127_-	DNA polymerase III subunit alpha	A0A2L1IZ23	Streptomyces_phage	8.3e-120	29.9
WP_002989617.1\|1018311_1018683_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_002984437.1\|1018682_1019381_+	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	6.6e-09	27.3
WP_002984433.1\|1019390_1020176_+	hypothetical protein	NA	NA	NA	NA
WP_023612208.1\|1020302_1020917_-	TVP38/TMEM64 family protein	M1Q152	Streptococcus_phage	4.0e-50	51.8
1021338:1021397	attL	NA	NA	NA	NA
WP_002993136.1\|1021507_1021696_-	hypothetical protein	A3F673	Streptococcus_phage	2.1e-18	76.3
WP_011184727.1\|1021935_1022694_+	DNase Mf2	NA	NA	NA	NA
WP_002985327.1\|1022804_1023512_+	streptococcal pyrogenic exotoxin SpeC	A0A097PAT7	Streptococcus_pyogenes_phage	3.9e-09	27.1
WP_011284838.1\|1023587_1024922_-	lysin	Q5MY96	Streptococcus_phage	1.3e-247	93.0
WP_011284839.1\|1025033_1025219_-	hypothetical protein	Q938J5	Temperate_phage	6.6e-25	96.7
WP_002990012.1\|1025215_1025512_-	hypothetical protein	Q938J6	Temperate_phage	3.7e-46	98.0
WP_011284840.1\|1025522_1026140_-	hypothetical protein	A3F662	Streptococcus_phage	9.8e-89	94.6
WP_002988795.1\|1026142_1026304_-	hypothetical protein	NA	NA	NA	NA
WP_111711139.1\|1026317_1028213_-	gp58-like family protein	Q938J9	Temperate_phage	5.9e-76	52.5
WP_011284842.1\|1028223_1028553_-	hypothetical protein	NA	NA	NA	NA
WP_011284843.1\|1028539_1029754_-	hypothetical protein	A3F657	Streptococcus_phage	5.0e-44	49.5
WP_111711140.1\|1029750_1031898_-\|tail	phage tail protein	Q938K1	Temperate_phage	0.0e+00	94.7
WP_024623478.1\|1031894_1032602_-	hypothetical protein	Q938K2	Temperate_phage	1.7e-92	70.6
WP_032461633.1\|1032601_1036525_-\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	2.6e-243	49.1
WP_021299462.1\|1036537_1036687_-	hypothetical protein	J7KBS0	Streptococcus_phage	1.7e-15	85.7
WP_021733367.1\|1036734_1037061_-	hypothetical protein	J7KK85	Streptococcus_phage	6.4e-39	75.0
WP_021341058.1\|1037113_1037725_-\|tail	phage major tail protein	J7KKC8	Streptococcus_phage	1.8e-74	73.0
WP_021341057.1\|1037741_1038167_-	hypothetical protein	J7KBZ9	Streptococcus_phage	2.9e-68	85.8
WP_021340627.1\|1038163_1038541_-	HK97 gp10 family phage protein	J7KDM3	Streptococcus_phage	1.8e-45	73.6
WP_029714354.1\|1038537_1038885_-\|head	phage head closure protein	J7KJ42	Streptococcus_phage	2.1e-48	84.5
WP_021341088.1\|1038881_1039184_-\|head,tail	phage head-tail connector protein	J7KC36	Streptococcus_phage	2.6e-42	87.8
WP_021341090.1\|1039328_1040513_-\|capsid	phage major capsid protein	J7KJ82	Streptococcus_phage	1.2e-162	76.1
WP_021341143.1\|1040536_1041202_-\|protease	Clp protease ClpP	M1Q115	Streptococcus_phage	5.4e-93	78.6
WP_032461634.1\|1041179_1042400_-\|portal	phage portal protein	J7KDU3	Streptococcus_phage	3.4e-186	81.7
WP_002985363.1\|1042433_1042658_-	hypothetical protein	Q938K9	Temperate_phage	3.6e-17	61.4
WP_002985365.1\|1042650_1042821_-	hypothetical protein	J7KK43	Streptococcus_phage	2.3e-08	62.5
WP_032461635.1\|1042817_1044572_-\|terminase	terminase large subunit	J7KKD1	Streptococcus_phage	0.0e+00	96.2
WP_002985371.1\|1044586_1045054_-\|terminase	phage terminase small subunit P27 family	J7KC46	Streptococcus_phage	3.9e-82	98.7
WP_021340284.1\|1045221_1045563_-	HNH endonuclease	J7KH36	Streptococcus_phage	2.5e-54	90.7
WP_011284866.1\|1046025_1046460_-	ArpU family transcriptional regulator	J7KDQ1	Streptococcus_phage	6.2e-74	97.9
WP_010922070.1\|1046740_1047376_-	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	2.0e-89	69.4
WP_032460570.1\|1047377_1047662_-	hypothetical protein	A0A097PAV1	Streptococcus_pyogenes_phage	2.8e-38	88.3
WP_032460569.1\|1047658_1048072_-	hypothetical protein	Q938M1	Temperate_phage	6.4e-36	65.2
WP_002987593.1\|1048081_1048351_-	hypothetical protein	A0A1P8VVR6	Streptococcus_phage	3.1e-47	100.0
WP_011017568.1\|1048347_1048632_-	DUF3310 domain-containing protein	A0A1P8VVP5	Streptococcus_phage	7.0e-50	100.0
WP_011284873.1\|1048873_1049230_-	hypothetical protein	A0A097PAU4	Streptococcus_pyogenes_phage	2.9e-61	100.0
WP_023079767.1\|1049213_1049564_-	VRR-NUC domain-containing protein	A0A1P8VVL5	Streptococcus_phage	9.9e-46	88.5
WP_014635521.1\|1049517_1050387_-	bifunctional DNA primase/polymerase	A0A1P8BME8	Lactococcus_phage	5.8e-103	65.6
WP_011284875.1\|1050655_1052209_-	hypothetical protein	A0A1P8BM51	Lactococcus_phage	5.7e-210	70.6
WP_002984328.1\|1052226_1052709_-	DUF669 domain-containing protein	A0A1P8BM40	Lactococcus_phage	9.7e-60	70.7
WP_075340263.1\|1052713_1054117_-	DEAD/DEAH box helicase	A0A1P8BMH7	Lactococcus_phage	2.3e-194	72.3
WP_002984321.1\|1054152_1054836_-	AAA family ATPase	J7KC09	Streptococcus_phage	9.4e-125	99.1
WP_011284877.1\|1054832_1055117_-	hypothetical protein	NA	NA	NA	NA
WP_002984315.1\|1055113_1055308_-	hypothetical protein	J7KK69	Streptococcus_phage	3.9e-12	54.2
WP_011284878.1\|1055307_1055637_-	hypothetical protein	J7KBZ0	Streptococcus_phage	7.9e-13	41.8
WP_011017881.1\|1055717_1055855_-	hypothetical protein	A0A097PAR2	Streptococcus_pyogenes_phage	3.4e-18	100.0
WP_011017882.1\|1055851_1056148_-	hypothetical protein	A0A097PAT8	Streptococcus_pyogenes_phage	3.1e-48	98.0
WP_011054585.1\|1056226_1056412_-	helix-turn-helix transcriptional regulator	A0A1X9I6I3	Streptococcus_phage	3.3e-16	72.1
WP_011284879.1\|1056578_1056818_+	hypothetical protein	NA	NA	NA	NA
WP_002984292.1\|1056967_1057177_+	hypothetical protein	NA	NA	NA	NA
WP_011017884.1\|1057435_1057945_+	hypothetical protein	NA	NA	NA	NA
WP_002984281.1\|1058052_1058280_-	hypothetical protein	A0A141E1R7	Streptococcus_phage	2.9e-14	57.3
WP_011054589.1\|1058353_1058740_+	hypothetical protein	A0A097PAT1	Streptococcus_pyogenes_phage	1.2e-65	100.0
WP_011284881.1\|1058728_1058938_-	hypothetical protein	A0A097PAQ9	Streptococcus_pyogenes_phage	1.7e-32	100.0
WP_011284882.1\|1058991_1059591_+	hypothetical protein	A0A097PAT4	Streptococcus_pyogenes_phage	3.1e-108	100.0
WP_011284883.1\|1059620_1059779_-	hypothetical protein	J7KH24	Streptococcus_phage	8.4e-21	90.4
WP_021341080.1\|1059837_1060053_+	hypothetical protein	J7KBX0	Streptococcus_phage	2.5e-28	95.7
WP_021340643.1\|1060038_1060188_-	hypothetical protein	J7KH12	Streptococcus_phage	4.3e-19	91.8
WP_111711142.1\|1060545_1061289_+	helix-turn-helix domain-containing protein	A0A1S5S8T5	Streptococcus_phage	7.4e-75	62.5
WP_023079768.1\|1061301_1062111_+	type II toxin-antitoxin system PemK/MazF family toxin	J7KDP1	Streptococcus_phage	2.9e-24	35.8
WP_023079773.1\|1062360_1063449_+\|integrase	site-specific integrase	Q38159	Streptococcus_phage	3.0e-202	98.6
WP_002989605.1\|1063811_1064432_+	DUF3862 domain-containing protein	NA	NA	NA	NA
1063492:1063587	attR	NA	NA	NA	NA
WP_023612202.1\|1064688_1066953_-	glycogen/starch/alpha-glucan family phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	1.2e-11	43.7

DBSCAN-SWA_6

1845933 : 1866158

Streptococcus_phage(56.25%)

holin,integrase

attL 1849132:1849152|attR 1863459:1863479

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002992187.1\|1845933_1847154_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	3.5e-05	23.6
WP_023612567.1\|1847164_1849147_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	3.0e-62	30.1
1849132:1849152	attL	NA	NA	NA	NA
WP_003058754.1\|1849241_1850393_-\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	3.6e-84	44.9
WP_011185066.1\|1850641_1850785_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_003058809.1\|1851646_1852414_-	helix-turn-helix domain-containing protein	Q76TK4	Streptococcus_pyogenes_phage	3.6e-72	83.1
WP_002992503.1\|1852567_1852774_+	helix-turn-helix transcriptional regulator	X2KUC2	Streptococcus_phage	2.4e-07	47.0
WP_002992502.1\|1852807_1853008_+	helix-turn-helix transcriptional regulator	A0A1S5SE31	Streptococcus_phage	3.4e-11	56.7
WP_002992501.1\|1853028_1853436_+	hypothetical protein	A0A1X9I5V7	Streptococcus_phage	1.3e-49	69.4
WP_011185071.1\|1853847_1854375_+	Rha family transcriptional regulator	R9QNB1	Lactococcus_phage	9.7e-21	40.2
WP_000132665.1\|1854622_1854796_+	hypothetical protein	NA	NA	NA	NA
WP_000074663.1\|1855013_1855187_+	hypothetical protein	NA	NA	NA	NA
WP_000916926.1\|1855327_1855780_+	hypothetical protein	NA	NA	NA	NA
WP_011285276.1\|1855881_1856214_+	hypothetical protein	NA	NA	NA	NA
WP_021340709.1\|1856213_1856405_+	hypothetical protein	NA	NA	NA	NA
WP_003058810.1\|1856416_1856746_+	hypothetical protein	NA	NA	NA	NA
WP_010922766.1\|1856748_1857021_+	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	3.6e-19	60.0
WP_011285278.1\|1857021_1857888_+	primase C-terminal domain-containing protein	A0A1X9I6L2	Streptococcus_phage	6.1e-121	73.8
WP_011285279.1\|1857899_1859294_+	phage protein	A0A1W6JQD6	Staphylococcus_phage	1.3e-48	38.1
WP_011285280.1\|1859587_1859842_+	hypothetical protein	NA	NA	NA	NA
WP_011285281.1\|1859838_1860012_+	hypothetical protein	A0A1X9I5U0	Streptococcus_phage	8.6e-11	59.6
WP_011285282.1\|1860017_1860191_+	hypothetical protein	NA	NA	NA	NA
WP_030126555.1\|1860192_1860702_+	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	1.9e-29	63.5
WP_002992480.1\|1860775_1861264_+	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	1.4e-45	54.9
WP_011285284.1\|1861667_1862030_+	DUF1492 domain-containing protein	NA	NA	NA	NA
WP_011285285.1\|1862004_1862388_+	ArpU family transcriptional regulator	Q938L8	Temperate_phage	3.7e-14	41.7
WP_011285286.1\|1862552_1863206_+	hypothetical protein	NA	NA	NA	NA
WP_023612569.1\|1863602_1866158_-	DNA mismatch repair protein MutS	A0A1V0SGG8	Hokovirus	1.2e-42	22.7
1863459:1863479	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LS483386

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection