CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483399	Streptococcus pyogenes strain NCTC8227 chromosome 1	3 crisprs	DinG,csm6,cas3,DEDDh,csa3	0	1	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483399_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483399_1

749792-749881

Orphan

II-A

Consensus_repeat	Method
GCTATGCTGTTTTGAATGGTCCCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483399_1

>merge|NZ_LS483399|1|749792-749881|CRISPRCasFinder
GCTATGCTGTTTTGAATGGTCCCAAAACCTCTTATGTTTTAAGACACCACTTTGGATAGTTTTAGAGCTATGCTGTTTTGAATGGTCTCC

>NZ_LS483399|1|1|749792-749881|CRISPRCasFinder
GCTATGCTGTTTTGAATGGTCCCA	AAACCTCTTATGTTTTAAGACACCACTTTGGATAGTTTTAGA
GCTATGCTGTTTTGAATGGTCTCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483399.1\|WP_111702038.1\|745637_746279_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483399.1\|WP_111702040.1\|746341_747472_+\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_LS483399.1\|WP_002984857.1\|743148_744105_+\|YbbR-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|227193
NZ_LS483399.1\|WP_002989931.1\|757639_758467_+\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	unknown	unknown	gnl\|CDD\|226239
NZ_LS483399.1\|WP_111702054.1\|761037_762084_+\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270264
NZ_LS483399.1\|WP_002989934.1\|756325_756817_+\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|225976
NZ_LS483399.1\|WP_111702044.1\|748233_748998_+\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_LS483399.1\|WP_002984858.1\|742300_743152_+\|TIGR00159-family-protein	unknown	unknown	gnl\|CDD\|224539
NZ_LS483399.1\|WP_002984836.1\|760255_761044_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|227095
NZ_LS483399.1\|WP_011528593.1\|756833_757643_+\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226238
NZ_LS483399.1\|WP_011017726.1\|758602_760252_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NZ_LS483399.1\|WP_111702048.1\|754085_754523_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_LS483399.1\|WP_111702052.1\|755875_756301_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
NZ_LS483399.1\|WP_011184463.1\|744158_745514_+\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NZ_LS483399.1\|WP_111702050.1\|754652_755669_+\|YeiH-family-putative-sulfate-export-transporter	unknown	unknown	gnl\|CDD\|225411
NZ_LS483399.1\|WP_002984851.1\|748997_749630_+\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
NZ_LS483399.1\|WP_111702042.1\|747481_748234_+\|acyl-[acyl-carrier-protein]-thioesterase	unknown	unknown	gnl\|CDD\|226401
NZ_LS483399.1\|WP_010922253.1\|750528_752361_+\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_LS483399.1\|WP_002984860.1\|740064_740856_-\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
NZ_LS483399.1\|WP_011184461.1\|740855_742199_-\|Mur-ligase-family-protein	unknown	unknown	gnl\|CDD\|223840

Protein	Function_ID	Function_description	E-value
NZ_LS483399.1\|WP_111702040.1\|746341_747472_+\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_LS483399.1\|WP_002984857.1\|743148_744105_+\|YbbR-like-domain-containing-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	3.12847e-114
NZ_LS483399.1\|WP_002989931.1\|757639_758467_+\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	gnl\|CDD\|226239	COG3716, ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism].	1.55707e-109
NZ_LS483399.1\|WP_111702054.1\|761037_762084_+\|extracellular-solute-binding-protein	gnl\|CDD\|270264	cd13546, PBP2_BitB, Substrate binding domain of a putative iron transporter BitB, a member of the type 2 periplasmic binding fold superfamily. The substrate domain of this group shows a high homology to the periplasmic component of ferric iron transporter (Fbp), but its biochemical characterization has not been performed. The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria from the Pasteurellaceae and Neisseriaceae families and is critical for survival of these pathogens within the host. After binding iron with high affinity, Fbp interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The ferric iron-binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.88753e-91
NZ_LS483399.1\|WP_002989934.1\|756325_756817_+\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	gnl\|CDD\|225976	COG3444, COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB [Carbohydrate transport and metabolism].	8.80769e-55
NZ_LS483399.1\|WP_111702044.1\|748233_748998_+\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.84001e-127
NZ_LS483399.1\|WP_002984858.1\|742300_743152_+\|TIGR00159-family-protein	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	2.09715e-101
NZ_LS483399.1\|WP_002984836.1\|760255_761044_+\|response-regulator-transcription-factor	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	5.79862e-82
NZ_LS483399.1\|WP_011528593.1\|756833_757643_+\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	gnl\|CDD\|226238	COG3715, ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism].	2.10148e-76
NZ_LS483399.1\|WP_011017726.1\|758602_760252_+\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	3.92596e-77
NZ_LS483399.1\|WP_002984860.1\|740064_740856_-\|type-1-glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	1.00186e-142
NZ_LS483399.1\|WP_111702052.1\|755875_756301_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	1.6728e-30
NZ_LS483399.1\|WP_011184463.1\|744158_745514_+\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_LS483399.1\|WP_111702050.1\|754652_755669_+\|YeiH-family-putative-sulfate-export-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	5.20392e-102
NZ_LS483399.1\|WP_002984851.1\|748997_749630_+\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	1.04206e-87
NZ_LS483399.1\|WP_111702042.1\|747481_748234_+\|acyl-[acyl-carrier-protein]-thioesterase	gnl\|CDD\|226401	COG3884, FatA, Acyl-ACP thioesterase [Lipid metabolism].	1.17846e-104
NZ_LS483399.1\|WP_010922253.1\|750528_752361_+\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_LS483399.1\|WP_111702048.1\|754085_754523_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	4.01251e-83
NZ_LS483399.1\|WP_011184461.1\|740855_742199_-\|Mur-ligase-family-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	3.56257e-111

>NZ_LS483399.1|WP_002984851.1|748997_749630_+|TIGR01906-family-membrane-protein
MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVFMSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLLYPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHQVLFVGDSSWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE
>NZ_LS483399.1|WP_111702044.1|748233_748998_+|TIGR01457-family-HAD-type-hydrolase
MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNNTTRTPEMVQSMLTNQFHVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIAAAGYVEELENPAYVVVGLDSQVTYETLAIATLAIQKGALFIGTNPDLNIPTERGLMPGAGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQNDIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL
>NZ_LS483399.1|WP_111702042.1|747481_748234_+|acyl-[acyl-carrier-protein]-thioesterase
MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGRSNNNLLVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGDLLVDILAYFALLNPDTRKVATIPEDLVAPFKTDFVKKLYRVPKMPLLEQSIDRDYYVRYFDIDMNGHVNNSKYLDWMYDVLGCAFLKTHQPLKITLKYVKEVSPGGQITSSYHLDQLTSYHQIISDGQLNAQAMIEWRAIKPIESETD
>NZ_LS483399.1|WP_111702040.1|746341_747472_+|oxygen-independent-coproporphyrinogen-III-oxidase
MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQEFESYDIHDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPEKIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKTAGFHNISIDLIYALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQNRVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGVSFEERYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD
>NZ_LS483399.1|WP_111702038.1|745637_746279_+|hypothetical-protein
MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTQKEDIQKRRIKQLTKNFERLLDTSSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAVNEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLTDMQEKLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSKP
>NZ_LS483399.1|WP_011184463.1|744158_745514_+|phosphoglucosamine-mutase
MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN
>NZ_LS483399.1|WP_002984857.1|743148_744105_+|YbbR-like-domain-containing-protein
MKRFLNSRPWLGMVSVFFAILLFLTAASSNHNNSSSQIYSPIETYTHSLKDVPIDMKYDSDKYFISGYSYGAEVYLTSTNRIKLDSEVNNDTRNFKIVADLTHSHPGTVSVNLRVENLPSGVTATVSPDKISVTIGKKESKVFPVRGSVDAKQIANGYEISKIETGVNKVEVTSDESTIALIDHVVAKLPDDQVLDRNYSSRVTLQAVSADGTILASAIDPAKTNLSVAVKKITKSVPIRVEAVGMMDDSLSDIQYKLSKQTAVISGSREVLEDIDEIIAEVNISDVTKNTSKTVSLSSSQVSIEPSVVTVQLTTTKK
>NZ_LS483399.1|WP_002984858.1|742300_743152_+|TIGR00159-family-protein
MNNLSSIDIKFLLSLFADPWLLAVHLLDILIVAYLIYRFIKALTGTKIMSLVQGVIFFLVLRFIAEWIGFTTITYLMNQVITYGVIAGVVIFTPEIRAGLEKFGRSTQVFLQKQYVSSESALVDALIKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPLNADISSQLLINIFIPNTPLHDGAVIVGQNKIVAACAYLPLSESKAISKEFGTRHRAAIGLSENSDALTIIVSEETGAISVTRKGQFLHDLSTDEFETVLRTYLMSDSNVTLPWYKKILGGKSK
>NZ_LS483399.1|WP_011184461.1|740855_742199_-|Mur-ligase-family-protein
MKMKTLLGIIAGKAAQSILTKLGRGSTYPGRLALACDKDILKDLSKDYDIVVVTGTNGKTLTTALTVGILKEAFGEIITNPSGANMITGITSTFLAAKKGKSGRQIAVLEIDEASLPRITTYLKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGARNAPKATILANGDSPIFSSKDIVNPVQYYGFDTAKHAPQLAHYNTEGILCPKCEHILQYRLNTYANLGDFICLNCGFKRPQLDYRLTELTTITNHSSEFIIDGQDYKINVGGLYNIYNALAAVSVAEFFGVSPEKIKAGFNKSKAVFGRQETFTIGDKSCTLILIKNPVGASQALEMIQLADYPFSLSVLLNANYADGIDTSWIWDANFELITQMPITEINAGGVRHSEIARRLRVTGFDDTKIKQAEKLEQIIETIEKQEAKHAYILATYTAMLEFRSLLADRHVVEKEMI
>NZ_LS483399.1|WP_002984860.1|740064_740856_-|type-1-glutamine-amidotransferase
MTYTSLKSPENQDYIYDLNIAHLYGNLMNTYGDNGNILMLKYVAEKLGARVTVDIVSINDTFEQDDYDIVFFGGGQDYEQSIVAKDLPSKKAALADYIANNKVVLAICGGFQLLGQYYVQANGVKIDGLGIMGHYTLNQHQNRFIGDIKIHNDEFNETYYGFENHQGRTFLSGDEKPLGRVVYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVNLAYRLVTTALKKKYGSAISLPSYDDILKQEITEEYADLKSKASFNKV
>NZ_LS483399.1|WP_010922253.1|750528_752361_+|elongation-factor-4
MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDTKK
>NZ_LS483399.1|WP_111702048.1|754085_754523_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
METSEELKQRIGDLSYEVTQHAATESPFTGEYDIFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET
>NZ_LS483399.1|WP_111702050.1|754652_755669_+|YeiH-family-putative-sulfate-export-transporter
MSTHLRKLPGLLLCLLLALPAWCLGRLFPIIGAPVFAILLGMLLALFYEHRDKAKEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALLVAYGLQKWLRLDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNMLAALLFPSLGQLLGLSNEGFAIFAGTAVNDTSSVTATATAWDAIHHSNTLDGATIVKLTRTLAILPITLGLSLYRAKKEHDIVTEEGFSLRKSFPRFILFFLLASLITTLMTSLGVADSFHSLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQLSLGIW
>NZ_LS483399.1|WP_111702052.1|755875_756301_+|PTS-sugar-transporter-subunit-IIA
MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYTSQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLAALLSLVFLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD
>NZ_LS483399.1|WP_002989934.1|756325_756817_+|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB
MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQMTLKMAVPNGMKLLIRSVEDSIKLFNDPRATDKRIFVIVNSVKDACAIAKEVPDLEAVNVANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQLVN
>NZ_LS483399.1|WP_011528593.1|756833_757643_+|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC
MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDMKVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGMLAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILVGSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYLKLPAVAVAALGAVICVISSQRDLELDAITRGAINKQTTFDSKESEEEDFFA
>NZ_LS483399.1|WP_002989931.1|757639_758467_+|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID
MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTLLPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAITAVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHYYSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKGAKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC
>NZ_LS483399.1|WP_011017726.1|758602_760252_+|sensor-histidine-kinase
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRYHRLISKQEALLDELGKNSLLPFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPNQGLLFASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGHYLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLAVPKLFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE
>NZ_LS483399.1|WP_002984836.1|760255_761044_+|response-regulator-transcription-factor
MYKLVIIEDEHIIRKWLRYAIDYKALDILVIGEAKDGKEGAVLIKESQPDIVLTDINMPIMTAFDMFEATKDQTYAKIILSGYADFPNARSAIHYGVLEFLTKPIEKAALWECLQTIIAKIEKQKGSNQKTDACVYIPLPQMTDQIPEVVKDILEWVHAHFQDKISTSRLAHDLGYSESYIYQNIKKHLQMPLSDYINQYRINQAIQLMQQEPDLMVYEIAQAVGIYDYRYFDRVFKKYLGQTVKAFKEEHFMKDTDRSKPC
>NZ_LS483399.1|WP_111702054.1|761037_762084_+|extracellular-solute-binding-protein
MLKFKRKWLLSFLLVIIILAIVNVAMCILSSSKKDSAKELVILTPNSQTILTGTIPAFEEKYGVKVRLIQGGTGQLIDQLGRKDKPLNADIFFGGNYTQFESHKDLFESYVSPQVSTVISDYQLPSHRATPYTINGSVLIVNNELARGLHITSYEDLLQPALKGKIAFADPNSSSSAFSQLTNILLAKGGYTSSEAWEYVKRLLLSMNSIRATSSSDVYESVAEGKMIVGLTYEDPCINLQKSGANVSIVYPDEGTVFVPSSVAIIKKAKAMKEAKQFINFILSSDVQNAFGQSTSNRPIRRDAQTSHEMKPLDEIITLKEDYGYVTRHKKKILNTYNRLHEALERGK

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Crispr_ID: NZ_LS483399_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483399_2

829299-829388

Orphan

Consensus_repeat	Method
ATCCAAAGATGCTGTTGAAGTTTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483399_2

>merge|NZ_LS483399|2|829299-829388|CRISPRCasFinder
ATCCAAAGATGCTGTTGAAGTTTATAGTGGTATTGCCGCAGAAACCGTTGAAGAAAAGTGGCAAGATACCAAAGATGCTGTTGAAGTTTA

>NZ_LS483399|2|2|829299-829388|CRISPRCasFinder
ATCCAAAGATGCTGTTGAAGTTTA	TAGTGGTATTGCCGCAGAAACCGTTGAAGAAAAGTGGCAAGA
TACCAAAGATGCTGTTGAAGTTTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483399.1\|WP_002984641.1\|827242_827992_+\|sortase	unknown	unknown	gnl\|CDD\|226287
NZ_LS483399.1\|WP_038433405.1\|831918_832767_+\|ribosome-biogenesis-GTPase-YlqF	unknown	unknown	gnl\|CDD\|236570
NZ_LS483399.1\|WP_111702100.1\|834554_836684_+\|type-I-DNA-topoisomerase	unknown	unknown	gnl\|CDD\|235516
NZ_LS483399.1\|WP_030127250.1\|836818_838165_+\|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO	unknown	unknown	gnl\|CDD\|235416
NZ_LS483399.1\|WP_011017769.1\|831259_831700_-\|DUF1836-domain-containing-protein	unknown	unknown	gnl\|CDD\|378076
NZ_LS483399.1\|WP_111702092.1\|815495_816752_+\|serine-hydroxymethyltransferase	unknown	unknown	gnl\|CDD\|234571
NZ_LS483399.1\|WP_002984629.1\|830612_831263_-\|hemolysin-III-family-protein	unknown	unknown	gnl\|CDD\|224191
NZ_LS483399.1\|WP_002984645.1\|823562_824546_-\|L-lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|178836
NZ_LS483399.1\|WP_111702094.1\|817736_818336_+\|lysozyme-family-protein	unknown	unknown	gnl\|CDD\|372680
NZ_LS483399.1\|WP_111693218.1\|833611_834448_+\|DNA-protecting-protein-DprA	unknown	unknown	gnl\|CDD\|223829
NZ_LS483399.1\|WP_002984643.1\|824736_827223_+\|DNA-gyrase-subunit-A	unknown	unknown	gnl\|CDD\|235502
NZ_LS483399.1\|WP_011528639.1\|822033_823404_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|181958
NZ_LS483399.1\|WP_011017766.1\|828074_828488_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319940
NZ_LS483399.1\|WP_111702102.1\|838318_839725_+\|pyruvate-carboxylase-subunit-B	unknown	unknown	gnl\|CDD\|79056
NZ_LS483399.1\|WP_111702096.1\|818345_820070_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_LS483399.1\|WP_111702098.1\|832756_833548_+\|ribonuclease-HII	unknown	unknown	gnl\|CDD\|234574
NZ_LS483399.1\|WP_003061265.1\|840081_840432_+\|biotin/lipoyl-binding-protein	unknown	unknown	gnl\|CDD\|236449
NZ_LS483399.1\|WP_002984648.1\|820066_821794_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_LS483399.1\|WP_002989793.1\|816758_817736_+\|nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|377262
NZ_LS483399.1\|WP_111702104.1\|839767_840082_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_LS483399.1\|WP_002984641.1\|827242_827992_+\|sortase	gnl\|CDD\|226287	COG3764, SrtA, Sortase (surface protein transpeptidase) [Cell envelope biogenesis, outer membrane].	1.65078e-74
NZ_LS483399.1\|WP_038433405.1\|831918_832767_+\|ribosome-biogenesis-GTPase-YlqF	gnl\|CDD\|236570	PRK09563, rbgA, GTPase YlqF; Reviewed.	5.13e-160
NZ_LS483399.1\|WP_111702100.1\|834554_836684_+\|type-I-DNA-topoisomerase	gnl\|CDD\|235516	PRK05582, PRK05582, type I DNA topoisomerase.	0
NZ_LS483399.1\|WP_030127250.1\|836818_838165_+\|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO	gnl\|CDD\|235416	PRK05335, PRK05335, tRNA (uracil-5-)-methyltransferase Gid; Reviewed.	0
NZ_LS483399.1\|WP_011017769.1\|831259_831700_-\|DUF1836-domain-containing-protein	gnl\|CDD\|378076	pfam08876, DUF1836, Domain of unknown function (DUF1836). This family of proteins are functionally uncharacterized.	2.69438e-38
NZ_LS483399.1\|WP_111702092.1\|815495_816752_+\|serine-hydroxymethyltransferase	gnl\|CDD\|234571	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed.	0
NZ_LS483399.1\|WP_002984629.1\|830612_831263_-\|hemolysin-III-family-protein	gnl\|CDD\|224191	COG1272, COG1272, Predicted membrane protein, hemolysin III homolog [General function prediction only].	1.15731e-65
NZ_LS483399.1\|WP_002984645.1\|823562_824546_-\|L-lactate-dehydrogenase	gnl\|CDD\|178836	PRK00066, ldh, L-lactate dehydrogenase; Reviewed.	0
NZ_LS483399.1\|WP_111702094.1\|817736_818336_+\|lysozyme-family-protein	gnl\|CDD\|372680	pfam13702, Lysozyme_like, Lysozyme-like.	3.75108e-78
NZ_LS483399.1\|WP_111693218.1\|833611_834448_+\|DNA-protecting-protein-DprA	gnl\|CDD\|223829	COG0758, Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion].	1.00869e-106
NZ_LS483399.1\|WP_002984643.1\|824736_827223_+\|DNA-gyrase-subunit-A	gnl\|CDD\|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
NZ_LS483399.1\|WP_011528639.1\|822033_823404_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|181958	PRK09564, PRK09564, coenzyme A disulfide reductase; Reviewed.	1.34423e-97
NZ_LS483399.1\|WP_011017766.1\|828074_828488_+\|VOC-family-protein	gnl\|CDD\|319940	cd08352, VOC_Bs_YwkD_like, vicinal oxygen chelate (VOC) family protein Bacillus subtilis YwkD and similar proteins. uncharacterized subfamily of vicinal oxygen chelate (VOC) family contains Bacillus subtilis YwkD and similar proteins. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	4.38958e-71
NZ_LS483399.1\|WP_111702102.1\|838318_839725_+\|pyruvate-carboxylase-subunit-B	gnl\|CDD\|79056	PRK12581, PRK12581, oxaloacetate decarboxylase; Provisional.	0
NZ_LS483399.1\|WP_111702096.1\|818345_820070_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.82545e-129
NZ_LS483399.1\|WP_111702098.1\|832756_833548_+\|ribonuclease-HII	gnl\|CDD\|234574	PRK00015, rnhB, ribonuclease HII; Validated.	2.05347e-108
NZ_LS483399.1\|WP_003061265.1\|840081_840432_+\|biotin/lipoyl-binding-protein	gnl\|CDD\|236449	PRK09282, PRK09282, pyruvate carboxylase subunit B; Validated.	5.32739e-28
NZ_LS483399.1\|WP_002984648.1\|820066_821794_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	3.59026e-157
NZ_LS483399.1\|WP_002989793.1\|816758_817736_+\|nucleoid-associated-protein	gnl\|CDD\|377262	pfam04245, NA37, 37-kD nucleoid-associated bacterial protein.	1.27144e-26

>NZ_LS483399.1|WP_011017766.1|828074_828488_+|VOC-family-protein
MKLNAIHHVAIIVSDYNLSKNFYVNKLGFEIIRENYRPDKHDYKLDLSCGRIELEIFGKVTSDPYYQAPPKRVSQPEFKSEACGLRHLAFRVTNIESYVDDLKSLGIPVEPIRHDDYTGEKMTFFFDPDGLPLELHE
>NZ_LS483399.1|WP_002984641.1|827242_827992_+|sortase
MVKKQKRRKIKSMSWARKLLIAVLLILGLALLFNKPIRNTLIARNSNKYQVTKVSKKQIKKNKEAKSTFDFQAVEPVSTESVLQAQMAAQQLPVIGGIAIPELGINLPIFKGLGNTELIYGAGTMKEEQVMGGENNYSLASHHIFGITGSSQMLFSPLERAQNGMSIYLTDKEKIYEYIIKDVFTVAPERVDVIDDTAGLKEVTLVTCTDIEATERIIVKGELKTEYDFDKAPADVLKAFNHSYNQVST
>NZ_LS483399.1|WP_002984643.1|824736_827223_+|DNA-gyrase-subunit-A
MQDRNLIDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVDGHGNFGSMDGDGAAAQRYTEARMSKIALELLRDINKNTVNFQDNYDGSEREPVVLPARFPNLLVNGATGIAVGMATNIPPHNLAESIDAVKMVMEHPDCTTRELMEVIPGPDFPTGALVMGRSGIHRAYDTGKGSIVLRSRTEIETTQTGRERIVVTEFPYGVNKTKVHEHIVRLAQEKRLEGITAVRDESSREGVRFVIEIRREASATVILNNLFKLTSLQTNFSFNMLAIENGVPKILSLRQIIDNYISHQKEVIIRRTRFDKDKAEARAHILEGLLIALDHLDEVIAIIRNSETDVIAQTELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIADLSDILAKPERIITIIKEEMDEIKRKYANPRRTELMVGEVLSLEDEDLIEEEDVLITLSNKGYIKRLAQDEFRAQKRGGRGVQGTGVNNDDFVRELVSTSTHDTLLFFTNFGRVYRLKAYEIPEYGRTAKGLPIVNLLKLEDGETIQTIINARKEETAGKSFFFTTKQGIVKRTEVSEFNNIRQNGLRALKLKEGDQLINVLLTSGQDDIIIGTHSGYSVRFNEASIRNMGRSATGVRGVKLREDDRVVGASRIRDNQEVLVITENGFGKRTSATDYPTKGRGGKGIKTANITPKNGQLAGLVTVDGTEDIMVITNKGVIIRTNVANISQTGRATLGVKIMKLDADAKIVTFTLVQPEDSSIAEINTDRENSISKNKDN
>NZ_LS483399.1|WP_002984645.1|823562_824546_-|L-lactate-dehydrogenase
MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEKTQGDAEDLSHALAFTSPKKIYAADYSDCHDADLVVLTAGAPQKPGETRLDLVEKNLRINKEVVTQIVASGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQALAAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDIDEQGLVDLFISVRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQPAIVGAYGIVRPVNIPLNDAELQKMQASANQLKAIIDEAFAKEEFASAAKN
>NZ_LS483399.1|WP_011528639.1|822033_823404_+|FAD-dependent-oxidoreductase
MSKIVVVGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGCGMALWIGEQIAGPEGLFYSDKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKNHVETYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIAKLENKDIKRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQLAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTTLGNGKIELFRNGAFLVNKRQETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTDLEGIGVQGSNGISIYGLHMVSTGLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYDKDSRRILGAQMAAREDVSMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMAALGAKD
>NZ_LS483399.1|WP_002984648.1|820066_821794_+|ABC-transporter-ATP-binding-protein
MIKTDHHLLKRVLQDLLKKPLPVCILVIASFVQVGLSVYLPVLIGKAVDMSLSVNSWQTLKWLLGQMLVVIVVNTLIQWVMPLVYSRLLYQYSQQLKDKLLEKIHRLPFAYLDRQTIGDLVSRVITDTEQLINGLQMVFNQFILGLLTILCTIIAMAQIDWLMLILVLVLTPSSLFLARFIAQKSFHYAQAQTKSRGNLAQFTEEILRQEGLVQLFNAQEQSICDYHVLNKTYCEASQKAIFYASTVNPATRFINSVIYALLAGLGAVRIMAGLFSVGQLTTFLNVVVQYTKPFNDISSVLAEIQSSLACAQRLYDLLDIEIKEQEHFLTFKASAVKGQIDFEEVSFSYQKDRPLLKDINFSVPAGSKVAIVGPTGAGKSTLINLLMRFYELDAGSIKLDKVPIKCYAKEELRSITGMVLQETWLKDATVHELIAYGSEEASRDEVVAAAKAAHAHFFIMQLPKTYDTYLSASDDALSQGQLQLLAIARMFLKKPKVLILDEATSSIDIRTEAVIQEALKELMRGRTSFIIAHRLSTIQSADLILVMDQGRLVEWGTHASLMSKNGCYARLQKIE
>NZ_LS483399.1|WP_111702096.1|818345_820070_+|ABC-transporter-ATP-binding-protein
MKRLRPYVKGYLKESILGPLFKLLEALFELLVPLLVANMIDISISQHNSQGILRVVLTLFGLATIGLLLSVTAQYFSSKAAVGFTRQMTDDLFKKIMFLSKEDQDHLGYASLLSRLTSDSFQIQTGINQFLRLFLRAPIIVCGAMVMAYWISPSLTLWFVMMVIVLLTLVFVMSHLLGPLYLLIRRETDHLVRLTSQQLQGIRVIKAFNQTKKELQAFKEQNMLLSRHQYQAATLANVLNPMTFLVVNLTLLILIWQGSWQVAHRSLSQGMLVALINYLLQILAELLKMTMLMGTINQSVTAAKRINQVFVLADEAPLPLLKDGPISTHLLTIRHLTFTYPGAAEPSLYDIQLSADQGEWIGIIGGTGAGKTTLIDLICQTYSQYSGEISLNWQGEVPKTLTEWRNVIALVPQKAQLFKGTIRSNLLLGQSMPISDEELWRALELAQAKEFVAALPEQLEAPVEAFGRHFSGGQRQRLAIARALLKPKPILILDDASSALDNETRGRLFKALKEELSDVLVILVTQSIKNLQFADKILVLEQGHQLDFASHDQLKVSNALYQEMLALYVKGEQK
>NZ_LS483399.1|WP_111702094.1|817736_818336_+|lysozyme-family-protein
MFRLLKRACSFLLLFVIYQSFVIHHNVQRVLAYKPMVEKTLAENDTKANVDLVLAMIYTETKGGEADVMQSSESSSGQKNSITDSQASIEHGVNLLSHNLALAEEAGVDSWTAVQAYNFGTAYIDYIAKHGGQNTVDLATTYSKTVVAPSLGNTSGQIYFYYHPLALISGGKLYKNGGNIYYSREVHFNLYLIELMSLF
>NZ_LS483399.1|WP_002989793.1|816758_817736_+|nucleoid-associated-protein
MLDSYIKRIVIHQFSPNDTELLLSDRLVSITPRIDEYFRKKLAKVFSDEAKRGQFEANNTFFTTIGDDLLETSVTIAQLWKEAFVISEDQKTNDLVFVQFDKDGEPFFAFLRIALKEQFAHLSDNYEHPFTVTQNNLPSPTQTPDEALVINLKSGQYYLIEKRVKHNGSFANYFSEHLLKVTPEQSVKKSIKMIEQTAQKIAEHFNQDDFTFQSKMKSTLFKQLEADDVLSPEKLADQLFDDNLTARLTFVDQVKDVIPEPIKISDIDHSRQIKKLENQKLSLSNGIELTVPNAIYQDAEAVEFLLNDDGTYSILIKNIEDIKTK
>NZ_LS483399.1|WP_111702092.1|815495_816752_+|serine-hydroxymethyltransferase
MIFDKGNVEDFDKELWDAIHAEEERQEHHIELIASENMVSKAVMAAQGSVLTNKYAEGYPGNRYYGGTECVDIVETLAIERAKKLFGAAFANVQAHSGSQANAAAYMALIEAGDTVLGMDLAAGGHLTHGSPVNFSGKTYHFVGYSVDADTEMLNYEAILEQAKAVQPKLIVAGASAYSRSIDFEKFRAIADHVGAYLMVDMAHIAGLVAAGVHPSPVPYAHIVTSTTHKTLRGPRGGLILTNDEALAKKINSAVFPGLQGGPLEHVIAAKAVAFKEALDPAFKDYAQAIIDNTAAMAAVFAQDDRFRLISGGTDNHVFLVDVTKVIANGKLAQNLLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVKESQTIAHLIIKALVNHNQTVILEEVRQEVRQLTDAFPLYKK
>NZ_LS483399.1|WP_002984629.1|830612_831263_-|hemolysin-III-family-protein
MNQTFKQSLPLSFSEEVANSVTHAIGAFAMLILLPISASYAYQTYDLKAAIGISIFVISLFLMFLSSTIYHSMAYGSVHKYILRIIDHSMIYIAIAGSYTPVALSLVSGWLGYIIIVLQWGITLFGILYKIFAKRINEKFSLMLYIVMGWLVVFILPVIIQKTSLAFGLLMLFGGLSYTIGAVFYAKKRPYFHMIWHLFILLASALQFIAITFFML
>NZ_LS483399.1|WP_011017769.1|831259_831700_-|DUF1836-domain-containing-protein
MIFPSLPYWKDLPDLDLYLDQVLLYVNQCTDFSEVSDNKSLTASMINNYVKHGYVTKPIKKKYQKQQLARLIAISLFKTVFPIQDISRVLEELQAQADSESLYNTFVTCWNQKAPIEEDIPPIVQVACQTVKDYHKTIYLSQEVTQ
>NZ_LS483399.1|WP_038433405.1|831918_832767_+|ribosome-biogenesis-GTPase-YlqF
MATIQWFPGHMSKARRQVQENVKHVDFVTILVDARLPLSSQNPMLTKIVGDKPKLMILNKADLADATRTKEWKAYYESQGIKTLAINSKEQSTVKKVTETAKELMADKIQRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQWLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFKTHYPSRLTKRFKNIPLEEEAPEIIMTLTRQLGFKDDYDRFYSLFVKEVRDGKLGQYTLDQVGDMDAD
>NZ_LS483399.1|WP_111702098.1|832756_833548_+|ribonuclease-HII
MPTSIKAIKESLEAVTSLLDPLFQELATDTRSGAQKALKSRQKAIQADLAEEERLEAMLSYEKALYKEGYQAIAGIDEVGRGPLAGPVVAACVILPQHCKIKGLNDSKKIPKSKHETIYQAVKEKALAIGIGIIDNQLIDEVNIYEATKLAMLEAIKQLEGQLTQPDYLLIDAMTLDIAIPQQSIIKGDANSLSIAAASIVAKVTRDQMMANYDRIFPGYGFAKNSGYGTKEHLQGLKAYGIAPIHRKSFEPVKSMCCDSTNP
>NZ_LS483399.1|WP_111693218.1|833611_834448_+|DNA-protecting-protein-DprA
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYPMALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTIAIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGRDIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY
>NZ_LS483399.1|WP_111702100.1|834554_836684_+|type-I-DNA-topoisomerase
MGTKTTTKPKTGTKKSTTKKKSTAKKNLVIVESPAKAKTIEKYLGRSYKVVASVGHIRDLKKSSMFIDFDNNYEPQYINIRGKGPLINSLKKEAKAAKKVYLASDPDREGEAISWHLSHILGLDPEDKNRVVFNEITKDAVKNAFVEPRQIDMNLVDSQQARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENEIKAFVPEEYWSIDGLFKKGTKKFQASFYGLDGKKMKLSNNDDVKAVLAKLKGDDFLVSKVEKKERRRNAPLPYTTSSLQQDAANKINFRTRKTMMVAQQLYEGIHLGENGTQGLITYMRTDSTRISPVAQNDAAQFISNRFGANYSKHGNRVKNTSGAQDAHEAIRPSSVNHTPEAIAKYLNKDQLKLYTLIWNRFVASQMTAAVFDTVKVNLEQNGVLFVANGSQMKFDGYMAVYNDSDKNKMLPEMEEGENVKKVSTSPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLEVIQRRYYVKLSAKRFEPTELGEIVNKLIVEFFPDIVDVAFTAEMEGKLDQVEIGEEEWQHVIDQFYQPFVKELNKAESEIEKIQIKDEPAGFDCDVCGHPMVIKLGRFGKFYACSNFPECRNTKAITKEIGVTCPICHKGQVIERKTKRNRIFYGCDRYPECDFTSWDLPVGRDCPKSGDYLIEKKVRGGKQVMCSNETCDYKEEKIK
>NZ_LS483399.1|WP_030127250.1|836818_838165_+|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO
MSQSTATYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQHKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEANRVPAGGAMAVDREGYAESVTAELENHPLIEVIRDEITEIPDDAITVIATGPLTSDALAEKIHALNGGDGFYFYDAAAPIIDKSTIDMSKVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPLNSFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLTETFQSRNNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKREEALVFPQTTAIGSLPHYVTHAESKHFQPMNVNFGIIKELEGPRIRDKKERYEAIASRALADLDTCLASL
>NZ_LS483399.1|WP_111702102.1|838318_839725_+|pyruvate-carboxylase-subunit-B
MIQFGGFSMQQQVAITETVLRDGHQSLMATRLPIEDMLPVLPILDKIGYYSLECWGGATFDACIRFLNEDPWERLRTLKKGLPNTRLQMLLRGQNLLGYRHYADDIVDKFISLSAQNGIDVFRIFDALNDPRNIRQALSAVKKTGKEAQLCIAYTTSPVHTLDYYLSLVKELVEMGADSICIKDMAGILTPKAAKELVAGIKAMTNLPLIVHTHATSGISQMTYLAAVEAGADRIDTALSPFSEGTSQPATESMYLALKEAGYDITLDETLLEQAANHLRQARQKYLADGTLDPSLLFPDPRTLQYQVPGGMLSNMLSQLKQANAESKLEEVLAEVPRVRKDLGYPPLVTPLSQMVGTQAAMNVILGKPYQMVSKEIKQYLAGDYGKTPAPVNEDLKRSQIGSAPVTTNRPADQLSPEFEVLKAEVADLAQTDEDVLTYALFPSVAKPFLTTKYQTDDVIKVTAFIKA
>NZ_LS483399.1|WP_111702104.1|839767_840082_+|hypothetical-protein
MTYSFIDILQVTLVSLFLVLTCLTGIMGLMMLSGKLLSQERKTLSQQASSIPQEQEADKLSGEALETLLAKDELARIAVMTSLAYASQEESGKRFEVIAVERKS
>NZ_LS483399.1|WP_003061265.1|840081_840432_+|biotin/lipoyl-binding-protein
MKRYEVTVNGQVYEVSLRELADGETVEVSQPAAPATEKEMNANAAGGGIQVKAPMSGTVLSIFATEGKAVKKGEAVLVLEAMKMENEILAPADGLVSKIHVVANQTVESEQVLISF

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Crispr_ID: NZ_LS483399_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483399_3

1658832-1658941

Orphan

Consensus_repeat	Method
AGCTGCTACTGAAGATTCCTCACTCTCAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483399_3

>merge|NZ_LS483399|3|1658832-1658941|CRISPRCasFinder
AGCTGCTACTGAAGATTCCTCACTCTCAGCTGGGATTTCTGGGGCTGCTGGAGTTTCTGGAGATGGGGTTTCCTCAGAAGGAGCTGCTACTGAAGGTTCCTCACTCTCAG

>NZ_LS483399|3|3|1658832-1658941|CRISPRCasFinder
AGCTGCTACTGAAGATTCCTCACTCTCAG	CTGGGATTTCTGGGGCTGCTGGAGTTTCTGGAGATGGGGTTTCCTCAGAAGG
AGCTGCTACTGAAGGTTCCTCACTCTCAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483399.1\|WP_111702319.1\|1667557_1669150_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|285470
NZ_LS483399.1\|WP_111702316.1\|1663608_1664679_-\|M-related-protein-Enn	unknown	unknown	gnl\|CDD\|224117
NZ_LS483399.1\|WP_111702315.1\|1659710_1663274_-\|C5a-peptidase-ScpA/B	unknown	unknown	gnl\|CDD\|173801
NZ_LS483399.1\|WP_111702320.1\|1670176_1671805_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_LS483399.1\|WP_003059481.1\|1652943_1653747_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223521
NZ_LS483399.1\|WP_010922708.1\|1653730_1654357_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224049
NZ_LS483399.1\|WP_002982485.1\|1657291_1658212_-\|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb	unknown	unknown	gnl\|CDD\|238499
NZ_LS483399.1\|WP_011529051.1\|1652110_1652932_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
NZ_LS483399.1\|WP_002982507.1\|1654438_1654639_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_LS483399.1\|WP_111702321.1\|1671906_1673295_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_LS483399.1\|WP_111702313.1\|1654807_1657279_-\|pneumococcal-type-histidine-triad-protein	unknown	unknown	gnl\|CDD\|273578
NZ_LS483399.1\|WP_041174199.1\|1649395_1651024_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173883
NZ_LS483399.1\|WP_002982472.1\|1669847_1670099_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483399.1\|WP_002991237.1\|1673291_1673945_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_LS483399.1\|WP_011529046.1\|1647209_1647716_+\|DNA-topology-modulation-protein	unknown	unknown	gnl\|CDD\|180911
NZ_LS483399.1\|WP_111681365.1\|1651136_1652114_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223674
NZ_LS483399.1\|WP_111702317.1\|1664886_1666071_-\|M-protein	unknown	unknown	gnl\|CDD\|224117
NZ_LS483399.1\|WP_111702312.1\|1647964_1648666_+\|exotoxin	unknown	unknown	gnl\|CDD\|280949
NZ_LS483399.1\|WP_111702318.1\|1666298_1667360_-\|YSIRK-type-signal-peptide-containing-protein	unknown	unknown	gnl\|CDD\|224117
NZ_LS483399.1\|WP_038431640.1\|1674038_1675256_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|182528

Protein	Function_ID	Function_description	E-value
NZ_LS483399.1\|WP_111702319.1\|1667557_1669150_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|285470	pfam08270, PRD_Mga, M protein trans-acting positive regulator (MGA) PRD domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This corresponds to the PRD like region.	2.12977e-53
NZ_LS483399.1\|WP_111702316.1\|1663608_1664679_-\|M-related-protein-Enn	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	5.94927e-10
NZ_LS483399.1\|WP_111702315.1\|1659710_1663274_-\|C5a-peptidase-ScpA/B	gnl\|CDD\|173801	cd07475, Peptidases_S8_C5a_Peptidase, Peptidase S8 family domain in Streptococcal C5a peptidases. Streptococcal C5a peptidase (SCP), is a highly specific protease and adhesin/invasin. The subtilisin-like protease domain is located at the N-terminus and contains a protease-associated domain inserted into a loop. There are three fibronectin type III (Fn) domains at the C-terminus. SCP binds to integrins with the help of Arg-Gly-Asp motifs which are thought to stabilize conformational changes required for substrate binding. Peptidases S8 or Subtilases are a serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	4.90774e-76
NZ_LS483399.1\|WP_111702320.1\|1670176_1671805_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	7.18285e-59
NZ_LS483399.1\|WP_003059481.1\|1652943_1653747_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.85753e-80
NZ_LS483399.1\|WP_010922708.1\|1653730_1654357_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224049	COG1124, DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.43974e-90
NZ_LS483399.1\|WP_002982485.1\|1657291_1658212_-\|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb	gnl\|CDD\|238499	cd01017, AdcA, Metal binding protein AdcA. These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AdcA proteins belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. They are comprised of two globular subdomains connected by a long alpha helix and they bind their ligand in the cleft between these domains. In addition, many of these proteins have a low complexity region containing metal binding histidine-rich motif (repetitive HDH sequence).	4.72316e-122
NZ_LS483399.1\|WP_011529051.1\|1652110_1652932_+\|ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	7.49909e-70
NZ_LS483399.1\|WP_002982507.1\|1654438_1654639_-\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	7.43573e-06
NZ_LS483399.1\|WP_111702321.1\|1671906_1673295_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.99007e-29
NZ_LS483399.1\|WP_111702313.1\|1654807_1657279_-\|pneumococcal-type-histidine-triad-protein	gnl\|CDD\|273578	TIGR01363, pneumococcal_histidine_triad_A_protein, streptococcal histidine triad protein. This model represents the N-terminal half of a family of Streptococcal proteins that contain a signal peptide and then up to five repeats of a region that includes a His-X-X-His-X-His (histidine triad) motif. Three repeats are found in the seed alignment. Additional copies in more poorly conserved regions may be detected. Members of this family from Streptococcus pneumoniae are suggested to cleave human C3, and the member PhpA has been shown in vaccine studies to be a protective antigen in mice. [Cellular processes, Pathogenesis].	0
NZ_LS483399.1\|WP_041174199.1\|1649395_1651024_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173883	cd08518, PBP2_NikA_DppA_OppA_like_19, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NZ_LS483399.1\|WP_002991237.1\|1673291_1673945_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	6.27645e-69
NZ_LS483399.1\|WP_011529046.1\|1647209_1647716_+\|DNA-topology-modulation-protein	gnl\|CDD\|180911	PRK07261, PRK07261, DNA topology modulation protein.	8.63503e-114
NZ_LS483399.1\|WP_111681365.1\|1651136_1652114_+\|ABC-transporter-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.91482e-107
NZ_LS483399.1\|WP_111702317.1\|1664886_1666071_-\|M-protein	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	3.08969e-11
NZ_LS483399.1\|WP_111702312.1\|1647964_1648666_+\|exotoxin	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	2.08862e-42
NZ_LS483399.1\|WP_111702318.1\|1666298_1667360_-\|YSIRK-type-signal-peptide-containing-protein	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	2.83334e-15
NZ_LS483399.1\|WP_038431640.1\|1674038_1675256_-\|ABC-transporter-permease	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	1.91424e-51

>NZ_LS483399.1|WP_002982485.1|1657291_1658212_-|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb
MKKGFFLMAMAVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYAMTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNLKKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKELGRLDPKHKDSYTKKAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGLKQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKTLSPLEAAPSGNKTYLENLRANLEVLYQQLK
>NZ_LS483399.1|WP_111702313.1|1654807_1657279_-|pneumococcal-type-histidine-triad-protein
MKKTYGYIGSVAAILLATHIGSYQLGKHHMGLATKDNQIAYIDDSKGKAKAPKTNKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHYHFYNGKVPYDAIISEELLMTDPNYRFKQSDVINEILDGYVIKVNGNYYVYLKPGSKRKNIRTKQQIAEQVAKGTKEAKEKGLAQVAHLSKEEVAAVNEAKRQGRYTTDDGYIFSPTDIIDDLGDAYLVPHGNHYHYIPKKDLSPSELAAAQAYWSQKQGRGARPSDYRPTPAPGRRKAPIPDVTPNPGQGHQPDNGGYHPAPPRPNDASQNKHQRDEFKGKTFKELLDQLHRLDLKYRHVEEDGLIFEPTQVIKSNAFGYVVPHGDHYHIIPRSQLSPLEMELADRYLAGQTEDNDSGSDHSKPSDKEVTHTFLGHRIKAYGKGLDGKPYDTSDAYVFSKESIHSVDKSGVTAKHGDHFHYIGFGELEQYELDEVANWVKAKGQADELAAALDQEQGKEKPLFDTKKVSRKVTKDGKVGYMMPKDGKDYFYARDQLDLTQIAFAEQELMLKDKKHYRYDIVDTGIEPRLAVDVSSLPMHAGNATYDTGSSFVIPHIDHIHVVPYSWLTRDQIATIKYVMQHPEVRPDIWSKPGHEESGSVIPNVTPLDKRAGMPNWQIIHSAEEVQKALAEGRFATPDGYIFDPRDVLAKETFVWKDGSFSIPRADGSSLRTINKSDLSQAEWQQAQELLAKKNAGDATDTDKPKEKQQADKSNENQQPSEASKEEEKESDDFIDSLPDYGLDRATLEDHINQLAQKANIDPKYLIFQPEGVQFYNKNGELVTYDIKTLQQINP
>NZ_LS483399.1|WP_002982507.1|1654438_1654639_-|CsbD-family-protein
MSEEKLKSKIEQASGGLKEGAGKLTGDKELEAKGFVEKTIAKGKELADDAKEAVEGAVDAVKEKLK
>NZ_LS483399.1|WP_010922708.1|1653730_1654357_+|ABC-transporter-ATP-binding-protein
MTLEAKKLGFYHKKDQWLFKEIDLEVAPGQILGIFGQSGCGKTSLSRVLAGFLQPKSGEVLVDGSHLPNKAFRPVQLIQQHPEQTMNPLWPMKKSLEEAYYPSQDLRDAFGIQEKWLKRRPSELSGGELQRFSIVRSLHPETKYLIADEMTTMLDSITQASVWKSLLEIVKDRNLGLIIISHEFDMLEKLCDACYMIEENRTQLFKHT
>NZ_LS483399.1|WP_003059481.1|1652943_1653747_+|ABC-transporter-ATP-binding-protein
MTETLLSIKDLSITFTQYGRFLKPFQSTPIQALNLEVKKGELLAIIGASGSGKSLLAHAIMDILPKNAAVTGDMIYRGQSLTSKRIKQLRGKEMTLIPQSVNYLDPSMKVKHQVRLGISENAKATQEGLFQQFGLKESDGDLYPFQLSGGMLRRVLFTTCISDTVSLIIADEPTPGLHPDALQMVLDQLRSFADKGISVIFITHDIVAASQIADRITIFKEGKAIETAPASFFSGGGEQLQTEFARRLWRTLPQQDFLKGVTHDLRG
>NZ_LS483399.1|WP_011529051.1|1652110_1652932_+|ABC-transporter-permease
MILKRRTMVLWQLGIAISLILSILALNLYFYRTPLETNAALRNLAPSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGALMGVFLATVFGVLAGLGNSFIDKIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKNKAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAEQPSVGIILSEAAKHISLGNWWLVIFPGLYLILVVNAFDTIGESLKKLFYPQTDHF
>NZ_LS483399.1|WP_111681365.1|1651136_1652114_+|ABC-transporter-permease
MKRTTIIIIWKIIRCVTLIFGVSVLTFVLLKQSPVDPVMASVNYDTSLTPAQYKAVAHHYGLDKPALVQYFIWLKNVIQGHLGTSLVYRQPVSDIIKSRAGASFILMGLSWILSGLIGFILGTLSAFHQGKLLDRVVRWFSYLQISVPTFWIGLIFLLIFSVQLGWFPIGISSPIGTLSQDITLADRIKHLMLPVFTLSILGIANVTLHTRTKMMSVLSSEYVLFARARGETQWQIFKHHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGLGSTLTEAGLKSDTPLLLAIVMIGTLFVFAGNLIADILNSIINPQLRRKV
>NZ_LS483399.1|WP_041174199.1|1649395_1651024_+|ABC-transporter-substrate-binding-protein
MSKYLKYFSIITLFLTGLILVACQQQKPQTKERQRKQRPKDELVVSMGAKLPHEFDPKDRYGVHNEGNITHSTLLKRSPELDIKGELAKTYHLSEDGLTWSFDLHDDFKFSNGEPVTADDVKFTYDMLKADGKAWDLTFIKNVEVVGKNQINIHLTEAHSTFTAQLTEIPIVPKKHYNDKYKSNPIGSGPYMVKEYKAGEQAIFVRNPYWHGKKPYFKKWTWVLLDENTALAALESGDVDMIYATPELASKKVKGTRLLDIPSNDVRGLSLPYVKKGVITDSPDGYPVGNDVTSDPAIRKALTIGLNRQKVLDTVLNGYGKPAYSIIDKTPFWNPKTAIKDNKVAKAKQLLTKAGWKEQADGSRKKGDLDAAFDLYYPTNDQLRANLAVEVAEQAKALGITIKLKASNWDEMATKSHDSALLYAGGRHHAQQFYESHHPSLAGKGWTNITFYNNPTVTKYLDKAMTSSDLDKANEYWKLAQWDGKTGASTLGDLPNVWLVSLNHTYIGDKRINVGKQGVHSHGHDWSLLTNIAEWTWDESTK
>NZ_LS483399.1|WP_111702312.1|1647964_1648666_+|exotoxin
MKKTKLIFSLTSIFIAIISRPVFGLEVDNNSLLRNIYSTIVYEYSDTVIDFKTSHNLVTKKLDVRDARDFFINSEIDEYAANDFKAGDRIAVFSVPFDWNYLPEGKVTAYTYGGITPYQKTSISKNIPVNLWINGKQISVPYNEISTNKTTVTAQEIDLKVRKFLIAQHQLYSSGSSYKSGKLVFHTNDNSDKYSFDLFYVGYRDKESIFKVYKDNKSFNIDKIGHLDIEIDS
>NZ_LS483399.1|WP_011529046.1|1647209_1647716_+|DNA-topology-modulation-protein
MKIAIIGHSGSGKSTLARFLGQHYHCEVFHLDQLHFSSNWQERSDHDMIADLSTCLLKQDWIIEGNYANCLYEERMSEADYIIYVNFSRFHCVYRAFKRYLNYRGKTRPDMADNCQEKFDVAFVKWILLDGRSRNQLKKYQSVVQKYSHKTIVLTNQKQLSHYMNTIN
>NZ_LS483399.1|WP_111702315.1|1659710_1663274_-|C5a-peptidase-ScpA/B
MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPVTEQAVETPQPTAVSEEVPSSKETKTPQTPDDAEETVADKANDLAPQAPAKTADTPATSKATIRDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKAKKEHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLADYARNYAQAIRDAVNLGAKVINMSFGNAALAYANLPDETKKAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSPDKQLTETAMVKTDDQQDKEMPVLSTNRFEPNKAYDYAYANRGMKEDDFKDVKGKIALIERGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKDNSKKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAKLSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYFSPRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDKFEVTVTVHNKSDKPQELYYQATVQTDKVDGKHFALAPKALYETSWQKITIPANSSKQVTVPIDASRFSKDLLAQMKNGYFLEGFVRFKQDPKKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSDAKDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGTFAKQDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLVAEVLDKEGNVVWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYTPISSGAKEQHTDFDVIVDNTTPEVATSATFSAEDRRLTLASKPKTSQPVYRERIAYTYMDEDLPTTEYISPNEDGTFTLPEEAETMEGATVPLKMSDFTYVVEDMAGNITYTPVTKLLEGHSNKPEQDGSDQAPDKKPETNPEQDGSGQAPDKKPETNPEQDGSGQAPDKKPEANPEQDGSGQTPDKKPETKPEQDSSGQTPGKKPAPGKTPQKGQPSRTLEKRSSKRDLATKASTKDQLPTTNDKDTNRLHLLKLVMTTFFLGLVAHIFKTKRTED
>NZ_LS483399.1|WP_111702316.1|1663608_1664679_-|M-related-protein-Enn
MTRQQTKKNYSLRKLKTGTASVAVALTVLGAGFANQTEVKAEGVRASDTTTNSEKISKLYDENSKLIEERADLLDKLEEKEDKLDNVERHYLRKLDQEYKEHQKEKQQQQQEQEERQKNQEQLERKYQREVEKRYQEQQQKQQQLEAENQKLTEANKVSEASRKGLSNDLEASRAAKKELEAKHQKLEADHQALEAKHQKLEADHQVSETSRKGLSRDLEASREANKKVTSELTQAKAQLSALEESKKLSEKEKAELQAKLDAQAKALKEQLAKQAEELAKLRAEKAAGSKTPATKPANKERSGRAAQTATRPIQNKGMRSQLPSTGEAANPFFTAAAATVMVSAGMLALKRKEEN
>NZ_LS483399.1|WP_111702317.1|1664886_1666071_-|M-protein
MVRKDTNRHYSLRKLKKGTASVAVALTVVGAGLAVNQTEVSAKALTRSTASNSETARQTINDYEIKNHNLTQENEKLTEQNKELTSEKEKLTTDNGRLTEQNTELTEQNKELKAEEHRLITENRGLTKKLSEAEEESVNKERENKEAIDTLKNILDETVKDKLAREQKSKQDIGALKQELAKKDEGNKISEASRQGLRRDLDASREAKKQVEKDLANLTAELDKVKEEKQVSDASRQGLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEQLAKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGEAANPFFTAAALTVMATAGVAAVVKRKEEN
>NZ_LS483399.1|WP_111702318.1|1666298_1667360_-|YSIRK-type-signal-peptide-containing-protein
MSKRNPNKHYSLRKLKTGTASVAVALTVLGTGLANTTDVKAESRGYQVPPRVLLPGKEANKVFEERKALEKQARELGDTINHMSQTISEQSRKIAALKSEAELKNQQALEALNNKNEQIAKLTNENAQLKEAIEGYVQTIQNASREIAAKQQELAAAKSQLEAKNAEIEALKQQDASKTEEIAKLQSEAATLENLLGSAKRELTDLQAKLDTATAEKAKLESQVAALEKQLEATKKELADLQAKLAATNQEKEKLEAEAKALKEQLAKQAEELAKLKADKASGAQKPDTKPGDKEVPTRPSQTRTNTNKAPMAQTKRQLPSTGEEITNPFFTAAALTVIASAGVFALKRKEEN
>NZ_LS483399.1|WP_111702319.1|1667557_1669150_-|helix-turn-helix-domain-containing-protein
MHVSKLFTSQQWRELKLISYLTENSNAIGVKDKELSKALNISMLTLQSCLTNMQFMKEVGGITYKDGYINIWYHQCCGLQEVYQKALRESPSLKLLELLFFRDFSSLEELAEELFVSLSTLKRLIKKTNTYLSHTFAISIVTSPVQVSGDERQIRLFYLKYFSEAYKISEWPFGDILNLKDCERLLSLLIKEVDVKVHFTLFQHLKILSGVNLIRYYKGYSCSYNNKKTSHRFSQLIQHSSEIQDLSRLFYLKFGLHLDEYTIAEMFSNHLNDKLEIGCAFEIINQDPTSGGRQVTNWIHLLDEMEIKLNLSITNKYEVAVTLHNASVLNEEDITANYLLFDYKKSYLNFYQKEHPRIYEAFVTSVEKLMQADNAQVSKELINQLTYCFFITWENSFLKVNQKDEKVRLLVIERSYNSVGNFLKKYIGEFFSITNFDELDCLTIDLVEIEKQYDVIVTDVMVGKSEELEIFFFYKMIPEAIIDRLNEFLNVSFTDNNVMVKNLEAPSPSKSHSDKEVQKPDNSVKQATSS
>NZ_LS483399.1|WP_002982472.1|1669847_1670099_-|hypothetical-protein
MIKKVTTPSQKTKKRVRNGYLLKLGTACLLLSILSYGIGLLGQPSMENTFMGIASVAMLGSVCFFIIFALNRIFDALEDNLRD
>NZ_LS483399.1|WP_111702320.1|1670176_1671805_-|CHAP-domain-containing-protein
MKKRKLLAVTLLSTILLNSAVPLVVADTSLRNNTSSTDQPTTADTATDDESETAKKDKKSKETASQHDTQKDHKPSHTHPTPPSNDTKQTDQASSEATDKPNKDKNDTKQPDSSDQSTPSPKDQSSQKESQNKDGRPTPSPDQQKDQTPDKTPEKSADKTPEKGPEKAAEKTPEPNRDAPKPIQPPLGAAAPVFAPWRESDKDLSKLKPSSRSSAAYVRHWTGDSAYTHNLLSRRYGITAEQLDGFLNSLGIHYDKERLNGKRLLEWEKLTGLDVRAIVAIAMAESSLGTQGVAKEKGANMFGYGAFDFNPNNAKKYSDEVAIRHMVEDTIIANKNQTFERQDLKAKKWSLGQLDTLIDGGVYFTDTSGSGQRRADIMTKLDQWIDDHGSTPEIPEHLKITSGTQFSEVPVGYKRSQPQNVLTYKSETYSFGQCTWYAYNRVKELGYQVDRYMGNGGDWQRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKEDGSILISESNVMGLGTISYRTFTAEQASLLTYVVGDKLPRP
>NZ_LS483399.1|WP_111702321.1|1671906_1673295_-|HAMP-domain-containing-histidine-kinase
MRLIKKTFLVINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKREFDQTSKQIKGKTVTEIRDILTKKINKDNIWYSLVDSDNQLLYPSLQLLDGVSESKDSQNVNIVTTFDNSYSNVKVMSQKVTLRDGKKMTLLGQSSLQPVTDASKVLLDLYPSLLIFSVTVGSIVAYLYSRTSSRRILSMSQTAKKMVNLEPNLTCTIHGKDEIAMLASDINRLYASLSTSIKSLQKEYEKASDSEREKSEFLRMTSHELKTPITSVIGMIDGMLYNVGDFADRDKYLRKCRDVLEGQAQLVQSILSLSKIETLASQNQELFSLKSSLEEEMEVFLVLSELKHLKVTINLEEQFVKANKVYLLKAIKNIIDNAFHYTKSGGQVMIQLKDNQLVIKNEAETLLTQQQMKQLFQPFYRPDYSRNRKDGGTGLGLFTTHQILDQHHLAYRFVVLDQRWMVFTIDFPSHHDD
>NZ_LS483399.1|WP_002991237.1|1673291_1673945_-|response-regulator-transcription-factor
MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTTSYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVTKPFSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTKKEYDIIDYLAKRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE
>NZ_LS483399.1|WP_038431640.1|1674038_1675256_-|ABC-transporter-permease
MEDIIAALGSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTENTKRQLIGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKGVKNALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMRFIKGSDFSDKDFIDQKQVIYLEKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGLTSGTEKIAYIPLHQWYNINGVVDATPEITIQTYRADDLKPVAKRVSDMLNQTIPKSDYMFGVMNLKEFERQLDNLNKSNFVLLAGIASISLIVGGIGVMNIMLVSVTERTREIGIKKALGARRKLILKQFLIEAVILTLLGGVIGVISGMVSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIKASKLDPIEALRFE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LS483399_1	1.1\|749816\|42\|NZ_LS483399\|CRISPRCasFinder	749816-749857	42	MK448771	Streptococcus phage Javan481, complete genome	8135-8176	10	0.762
NZ_LS483399_1	1.1\|749816\|42\|NZ_LS483399\|CRISPRCasFinder	749816-749857	42	MK448862	Streptococcus phage Javan178, complete genome	8111-8152	10	0.762
NZ_LS483399_1	1.1\|749816\|42\|NZ_LS483399\|CRISPRCasFinder	749816-749857	42	MK448775	Streptococcus phage Javan489, complete genome	12024-12065	10	0.762
NZ_LS483399_1	1.1\|749816\|42\|NZ_LS483399\|CRISPRCasFinder	749816-749857	42	MK448969	Streptococcus phage Javan514, complete genome	11006-11047	10	0.762
NZ_LS483399_1	1.1\|749816\|42\|NZ_LS483399\|CRISPRCasFinder	749816-749857	42	MK448681	Streptococcus phage Javan141, complete genome	7911-7952	10	0.762
NZ_LS483399_1	1.1\|749816\|42\|NZ_LS483399\|CRISPRCasFinder	749816-749857	42	MK448794	Streptococcus phage Javan525, complete genome	10219-10260	10	0.762
NZ_LS483399_1	1.1\|749816\|42\|NZ_LS483399\|CRISPRCasFinder	749816-749857	42	MK448972	Streptococcus phage Javan520, complete genome	8060-8101	10	0.762
NZ_LS483399_1	1.1\|749816\|42\|NZ_LS483399\|CRISPRCasFinder	749816-749857	42	MK448763	Streptococcus phage Javan451, complete genome	9253-9294	10	0.762
NZ_LS483399_1	1.1\|749816\|42\|NZ_LS483399\|CRISPRCasFinder	749816-749857	42	MK448774	Streptococcus phage Javan487, complete genome	8120-8161	10	0.762
NZ_LS483399_1	1.1\|749816\|42\|NZ_LS483399\|CRISPRCasFinder	749816-749857	42	MK448773	Streptococcus phage Javan485, complete genome	11006-11047	10	0.762
NZ_LS483399_1	1.1\|749816\|42\|NZ_LS483399\|CRISPRCasFinder	749816-749857	42	MK448958	Streptococcus phage Javan486, complete genome	10360-10401	10	0.762
NZ_LS483399_1	1.1\|749816\|42\|NZ_LS483399\|CRISPRCasFinder	749816-749857	42	MK448777	Streptococcus phage Javan491, complete genome	8351-8392	10	0.762
NZ_LS483399_1	1.1\|749816\|42\|NZ_LS483399\|CRISPRCasFinder	749816-749857	42	MK448765	Streptococcus phage Javan459, complete genome	10219-10260	10	0.762
NZ_LS483399_1	1.1\|749816\|42\|NZ_LS483399\|CRISPRCasFinder	749816-749857	42	MK448675	Streptococcus phage Javan129, complete genome	12189-12230	11	0.738
NZ_LS483399_1	1.1\|749816\|42\|NZ_LS483399\|CRISPRCasFinder	749816-749857	42	MK448944	Streptococcus phage Javan452, complete genome	12399-12440	11	0.738
NZ_LS483399_1	1.1\|749816\|42\|NZ_LS483399\|CRISPRCasFinder	749816-749857	42	MK448672	Streptococcus phage Javan117, complete genome	7980-8021	11	0.738
NZ_LS483399_1	1.1\|749816\|42\|NZ_LS483399\|CRISPRCasFinder	749816-749857	42	MK448849	Streptococcus phage Javan128, complete genome	7884-7925	11	0.738
NZ_LS483399_1	1.1\|749816\|42\|NZ_LS483399\|CRISPRCasFinder	749816-749857	42	MK448850	Streptococcus phage Javan132, complete genome	12709-12750	11	0.738

1. spacer 1.1|749816|42|NZ_LS483399|CRISPRCasFinder matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataagatctga	Protospacer
    ***********************.******.  *. **

2. spacer 1.1|749816|42|NZ_LS483399|CRISPRCasFinder matches to MK448862 (Streptococcus phage Javan178, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
gtcgctcttatgttttaagacaccactctggataaggtctga	Protospacer
.   ***********************.******.  *. **

3. spacer 1.1|749816|42|NZ_LS483399|CRISPRCasFinder matches to MK448775 (Streptococcus phage Javan489, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataaggtctga	Protospacer
    ***********************.******.  *. **

4. spacer 1.1|749816|42|NZ_LS483399|CRISPRCasFinder matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataagatctga	Protospacer
    ***********************.******.  *. **

5. spacer 1.1|749816|42|NZ_LS483399|CRISPRCasFinder matches to MK448681 (Streptococcus phage Javan141, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
gtcgctcttatgttttaagacaccactctggataaggtctga	Protospacer
.   ***********************.******.  *. **

6. spacer 1.1|749816|42|NZ_LS483399|CRISPRCasFinder matches to MK448794 (Streptococcus phage Javan525, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataaggtctga	Protospacer
    ***********************.******.  *. **

7. spacer 1.1|749816|42|NZ_LS483399|CRISPRCasFinder matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataagatctga	Protospacer
    ***********************.******.  *. **

8. spacer 1.1|749816|42|NZ_LS483399|CRISPRCasFinder matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataagatctga	Protospacer
    ***********************.******.  *. **

9. spacer 1.1|749816|42|NZ_LS483399|CRISPRCasFinder matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataagatctga	Protospacer
    ***********************.******.  *. **

10. spacer 1.1|749816|42|NZ_LS483399|CRISPRCasFinder matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataagatctga	Protospacer
    ***********************.******.  *. **

11. spacer 1.1|749816|42|NZ_LS483399|CRISPRCasFinder matches to MK448958 (Streptococcus phage Javan486, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataaggtctga	Protospacer
    ***********************.******.  *. **

12. spacer 1.1|749816|42|NZ_LS483399|CRISPRCasFinder matches to MK448777 (Streptococcus phage Javan491, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataaggtctga	Protospacer
    ***********************.******.  *. **

13. spacer 1.1|749816|42|NZ_LS483399|CRISPRCasFinder matches to MK448765 (Streptococcus phage Javan459, complete genome) position: , mismatch: 10, identity: 0.762

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
tttactcttatgttttaagacaccactctggataaggtctga	Protospacer
    ***********************.******.  *. **

14. spacer 1.1|749816|42|NZ_LS483399|CRISPRCasFinder matches to MK448675 (Streptococcus phage Javan129, complete genome) position: , mismatch: 11, identity: 0.738

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
gtcgctattatgttttaagacaccactctggataaggtctga	Protospacer
.   ** ********************.******.  *. **

15. spacer 1.1|749816|42|NZ_LS483399|CRISPRCasFinder matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 11, identity: 0.738

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
gtcgctcttatgttttaagacaccgctctggataaggtctga	Protospacer
.   ********************.**.******.  *. **

16. spacer 1.1|749816|42|NZ_LS483399|CRISPRCasFinder matches to MK448672 (Streptococcus phage Javan117, complete genome) position: , mismatch: 11, identity: 0.738

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
gtcgctcttatgttttaagacaccgctctggataaggtctga	Protospacer
.   ********************.**.******.  *. **

17. spacer 1.1|749816|42|NZ_LS483399|CRISPRCasFinder matches to MK448849 (Streptococcus phage Javan128, complete genome) position: , mismatch: 11, identity: 0.738

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
gtcgctcttatgttttaagacaccgctctggataaggtctga	Protospacer
.   ********************.**.******.  *. **

18. spacer 1.1|749816|42|NZ_LS483399|CRISPRCasFinder matches to MK448850 (Streptococcus phage Javan132, complete genome) position: , mismatch: 11, identity: 0.738

aaacctcttatgttttaagacaccactttggatagttttaga	CRISPR spacer
gtcgctcttatgttttaagacaccgctctggataaggtctga	Protospacer
.   ********************.**.******.  *. **

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

30498 : 42820

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111701703.1\|30498_34224_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	3.0e-39	26.7
WP_111701705.1\|34384_35839_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	6.3e-54	32.7
WP_011184062.1\|35866_36889_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	2.4e-63	41.7
WP_002986700.1\|37056_37611_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.4e-25	36.1
WP_111701707.1\|37794_39342_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	2.8e-44	51.8
WP_023078180.1\|39400_40525_-	SH3 domain-containing protein	F8HGP2	Streptococcus_phage	1.0e-06	28.6
WP_021340276.1\|40777_42043_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_111701709.1\|42328_42820_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.2e-18	42.3

DBSCAN-SWA_2

317239 : 373615

Streptococcus_phage(33.33%)

tRNA,protease,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002985850.1\|317239_317830_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	2.6e-54	55.7
WP_002985847.1\|318321_318597_+	YlbG family protein	NA	NA	NA	NA
WP_011184214.1\|318845_319481_+	dTMP kinase	M1PSC7	Streptococcus_phage	9.2e-66	63.9
WP_002985844.1\|319498_320374_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.1e-68	46.6
WP_011017422.1\|320392_320632_+	hypothetical protein	NA	NA	NA	NA
WP_002985838.1\|321035_321359_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.3e-28	59.4
WP_111701810.1\|321363_322227_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	5.5e-114	74.3
WP_002985833.1\|322253_322646_+	hypothetical protein	NA	NA	NA	NA
WP_009880724.1\|322692_323322_-	copper homeostasis protein CutC	NA	NA	NA	NA
WP_011184219.1\|323621_323978_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	6.3e-40	65.8
WP_011889118.1\|324051_324879_-	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	4.5e-129	79.3
WP_021340507.1\|325112_326294_+	L-lactate oxidase	NA	NA	NA	NA
WP_111701812.1\|326559_331509_+\|protease	CXC chemokine-degrading serine protease SpyCEP	NA	NA	NA	NA
WP_042765607.1\|332280_332988_+	DUF1275 domain-containing protein	NA	NA	NA	NA
WP_111701814.1\|333227_335228_+\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	6.0e-87	35.1
WP_011889113.1\|335722_336736_+	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	7.2e-97	53.0
WP_002990870.1\|336739_337228_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	R4JF54	Bacillus_phage	1.3e-11	37.5
WP_111701816.1\|337194_339375_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	2.8e-170	43.1
WP_111701818.1\|339578_340331_-	ADP-ribosyltransferase	NA	NA	NA	NA
WP_111701820.1\|340787_341183_+	hypothetical protein	NA	NA	NA	NA
WP_111701822.1\|341399_341651_+	hypothetical protein	NA	NA	NA	NA
WP_111701824.1\|341745_342360_-	hypothetical protein	NA	NA	NA	NA
WP_111701826.1\|342720_342957_+	DUF2829 domain-containing protein	NA	NA	NA	NA
WP_021340581.1\|342949_343648_+	3-oxoacyl-ACP reductase	A0A0N9R355	Chrysochromulina_ericina_virus	1.2e-10	25.2
WP_111701828.1\|343723_344683_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_002993065.1\|345015_346353_+	MFS transporter	NA	NA	NA	NA
WP_011889106.1\|346526_347909_+	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L4K9	Tupanvirus	3.8e-32	36.4
WP_111701830.1\|347939_348494_+	NUDIX hydrolase	NA	NA	NA	NA
WP_002990826.1\|348493_348745_+	hypothetical protein	NA	NA	NA	NA
WP_010921957.1\|348764_349460_+	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_111701832.1\|349610_349952_+	hypothetical protein	NA	NA	NA	NA
WP_111701834.1\|350050_350698_-	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_111701836.1\|350843_351776_+	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002985780.1\|351839_352565_+	metal ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.4e-17	32.6
WP_023605027.1\|352565_353420_+	metal ABC transporter permease	NA	NA	NA	NA
WP_002985776.1\|353567_354374_-	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.5e-20	36.6
WP_111701838.1\|354590_356996_+	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	3.8e-88	51.7
WP_010921962.1\|357065_357419_-	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_002990800.1\|357662_358088_+	50S ribosomal protein L11	NA	NA	NA	NA
WP_002985768.1\|358193_358883_+	50S ribosomal protein L1	NA	NA	NA	NA
WP_002985765.1\|359204_359933_+	UMP kinase	NA	NA	NA	NA
WP_002985763.1\|359961_360519_+	ribosome recycling factor	NA	NA	NA	NA
WP_111701840.1\|360627_361485_+	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_002985759.1\|361557_362067_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_002985757.1\|362063_362279_+	YozE family protein	NA	NA	NA	NA
WP_038433670.1\|362434_363604_+	LysM peptidoglycan-binding domain-containing protein	A0A0E3XB61	Gordonia_phage	5.5e-16	40.5
WP_002990789.1\|363916_365689_+	oleate hydratase	NA	NA	NA	NA
WP_002990786.1\|365847_366900_+	PhoH family protein	W8D063	Erwinia_phage	1.2e-46	50.0
WP_002990783.1\|366945_367521_+	uracil-DNA glycosylase family protein	NA	NA	NA	NA
WP_172452963.1\|367628_368177_+	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_002985746.1\|368157_368565_+	diacylglycerol kinase	NA	NA	NA	NA
WP_002985743.1\|368684_369581_+	GTPase Era	NA	NA	NA	NA
WP_002985741.1\|369600_370077_+	NUDIX hydrolase	NA	NA	NA	NA
WP_111701844.1\|371281_371464_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_111702361.1\|372686_372914_+\|bacteriocin	bacteriocin BlpM	NA	NA	NA	NA
WP_003060803.1\|372926_373127_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_111701846.1\|373420_373615_+\|bacteriocin	bacteriocin	NA	NA	NA	NA

DBSCAN-SWA_3

598818 : 609421

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111701977.1\|598818_601029_-	LTA synthase family protein	W6LM83	Streptococcus_phage	1.4e-267	68.6
WP_002985142.1\|601136_602300_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	3.4e-143	65.1
WP_002985140.1\|602296_602983_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.0e-88	68.9
WP_111701979.1\|603076_604243_+	chorismate synthase	A0A291AU41	Pandoravirus	2.6e-34	33.1
WP_002990260.1\|604303_604645_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	2.6e-19	41.1
WP_111701981.1\|604865_606218_+	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	1.0e-29	24.0
WP_002990257.1\|606305_607574_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_111701983.1\|607603_608044_-	hypothetical protein	NA	NA	NA	NA
WP_109991877.1\|608278_609421_+	cysteine desulfurase	H7BUW1	unidentified_phage	3.5e-15	32.1

DBSCAN-SWA_4

905852 : 989620

Streptococcus_phage(60.94%)

portal,transposase,protease,integrase,terminase,head,holin,tRNA,tail,capsid

attL 942783:942842|attR 986159:986257

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111702121.1\|905852_906737_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_111702122.1\|906852_908193_-	DUF2130 domain-containing protein	NA	NA	NA	NA
WP_111702123.1\|908289_909246_-	aromatic acid exporter family protein	NA	NA	NA	NA
WP_111702124.1\|909256_909853_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_111702125.1\|909944_912581_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_002989664.1\|912595_913297_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.9e-36	37.0
WP_011017823.1\|913414_913957_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_002984480.1\|914098_914740_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_021340922.1\|914902_915391_-	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_111702126.1\|915401_915602_-	CsbD family protein	J7KJ36	Streptococcus_phage	7.9e-08	51.5
WP_002984475.1\|915642_916182_-	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_011888836.1\|916194_916383_-	DUF2273 domain-containing protein	NA	NA	NA	NA
WP_002984470.1\|916393_917005_-	alkaline shock response membrane anchor protein AmaP	NA	NA	NA	NA
WP_002984469.1\|917041_917290_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_002989648.1\|917652_919971_-	DNA helicase PcrA	A7KV33	Bacillus_phage	3.5e-131	41.2
WP_111702127.1\|920500_921823_+	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_111702128.1\|921942_923178_+	cation diffusion facilitator family transporter	NA	NA	NA	NA
WP_111702129.1\|923547_924321_-	CAMP factor pore-forming toxin Cfa	NA	NA	NA	NA
WP_002984460.1\|924688_925525_-	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002984457.1\|925540_926170_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-27	35.5
WP_002984455.1\|926179_926821_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_011017832.1\|926927_927263_-	alkylphosphonate utilization protein	NA	NA	NA	NA
WP_111702131.1\|927429_928563_-\|transposase	ISAs1-like element IS1548 family transposase	NA	NA	NA	NA
WP_038433353.1\|929569_931384_-	glutamine--fructose-6-phosphate transaminase (isomerizing)	A0A1J0F994	Only_Syngen_Nebraska_virus	2.8e-99	37.4
WP_038433352.1\|931655_933104_+\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	4.6e-254	91.5
WP_011184572.1\|933116_933674_-	signal peptidase I	NA	NA	NA	NA
WP_011184573.1\|933803_935306_-	pyruvate kinase	NA	NA	NA	NA
WP_002984444.1\|935368_936382_-	6-phosphofructokinase	NA	NA	NA	NA
WP_111702133.1\|936461_939572_-	DNA polymerase III subunit alpha	A0A2L1IZ23	Streptomyces_phage	7.1e-119	29.9
WP_002989617.1\|939756_940128_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_002984437.1\|940127_940826_+	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	6.6e-09	27.3
WP_111702134.1\|940835_941621_+	ABC transporter permease	NA	NA	NA	NA
WP_002989607.1\|941747_942362_-	TVP38/TMEM64 family protein	M1Q152	Streptococcus_phage	6.2e-51	52.3
942783:942842	attL	NA	NA	NA	NA
WP_111702135.1\|942952_943141_-	Paratox	A3F673	Streptococcus_phage	1.0e-20	83.1
WP_011285611.1\|943379_944180_+	streptodornase Sda3	NA	NA	NA	NA
WP_011017966.1\|944450_944885_+	hypothetical protein	NA	NA	NA	NA
WP_111702137.1\|946632_947190_-	glycoside hydrolase family 73 protein	Q938J4	Temperate_phage	1.8e-97	91.9
WP_000609113.1\|947305_947533_-\|holin	phage holin	A7J2B3	Streptococcus_phage	5.8e-31	98.7
WP_023610930.1\|947529_947802_-	hypothetical protein	A7J2B2	Streptococcus_phage	5.0e-37	93.3
WP_020833519.1\|947811_948429_-	DUF1366 domain-containing protein	Q938J7	Temperate_phage	1.5e-76	88.3
WP_002987513.1\|948431_948863_-	DUF1617 family protein	Q938J8	Temperate_phage	1.1e-73	100.0
WP_111702138.1\|948874_950890_-	gp58-like family protein	Q938J9	Temperate_phage	2.2e-182	72.6
WP_030127700.1\|950902_951928_-	hyaluronoglucosaminidase	Q938K0	Temperate_phage	6.2e-173	93.5
WP_111702139.1\|951924_954072_-\|tail	phage tail protein	Q938K1	Temperate_phage	0.0e+00	93.7
WP_109820925.1\|954068_954776_-\|tail	phage tail family protein	Q938K2	Temperate_phage	1.6e-90	68.5
WP_111702140.1\|954775_958699_-\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	2.2e-250	49.6
WP_168625219.1\|958711_958876_-	hypothetical protein	J7KBS0	Streptococcus_phage	6.9e-10	84.6
WP_021733367.1\|958907_959234_-	hypothetical protein	J7KK85	Streptococcus_phage	6.4e-39	75.0
WP_111702371.1\|959286_959898_-\|tail	phage tail protein	J7KKC8	Streptococcus_phage	1.9e-76	75.1
WP_003055350.1\|959914_960340_-	hypothetical protein	J7KBZ9	Streptococcus_phage	5.9e-69	85.8
WP_003055321.1\|960336_960714_-	HK97 gp10 family phage protein	J7KDM3	Streptococcus_phage	1.5e-47	76.0
WP_003055344.1\|960710_961058_-\|head	phage head closure protein	J7KJ42	Streptococcus_phage	2.6e-46	80.9
WP_109820928.1\|961054_961357_-\|head,tail	phage head-tail connector protein	J7KC36	Streptococcus_phage	3.6e-44	90.8
WP_153276911.1\|961359_961521_-	hypothetical protein	J7KH04	Streptococcus_phage	2.0e-17	86.8
WP_109820929.1\|961534_962722_-\|capsid	phage major capsid protein	J7KJ82	Streptococcus_phage	3.9e-179	84.3
WP_109820930.1\|962746_963412_-\|protease	Clp protease ClpP	M1Q115	Streptococcus_phage	2.1e-92	78.1
WP_109820931.1\|963389_964610_-\|portal	phage portal protein	J7KDU3	Streptococcus_phage	2.4e-187	82.2
WP_111702141.1\|964678_965422_-	phage antirepressor KilAC domain-containing protein	M1PKL6	Streptococcus_phage	9.1e-73	56.9
WP_002984380.1\|965423_965672_-	hypothetical protein	NA	NA	NA	NA
WP_011017861.1\|965786_965966_-	hypothetical protein	M1NRK8	Streptococcus_phage	2.6e-18	79.7
WP_002984375.1\|966050_966320_-	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	2.3e-34	84.1
WP_168388874.1\|966312_966483_-	hypothetical protein	J7KK43	Streptococcus_phage	3.9e-08	56.2
WP_111702142.1\|966479_968234_-\|terminase	terminase large subunit	J7KKD1	Streptococcus_phage	0.0e+00	98.3
WP_109820934.1\|968248_968716_-\|terminase	phage terminase small subunit P27 family	J7KC46	Streptococcus_phage	4.3e-81	97.4
WP_002985375.1\|968887_969226_-	HNH endonuclease	J7KH36	Streptococcus_phage	3.0e-55	90.7
WP_111702143.1\|969772_970207_-	ArpU family transcriptional regulator	J7KDQ1	Streptococcus_phage	4.5e-72	95.8
WP_111702144.1\|970231_970660_-	DUF1642 domain-containing protein	A0A097PAV5	Streptococcus_pyogenes_phage	8.2e-10	38.4
WP_111702145.1\|970662_971295_-	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	3.4e-81	66.2
WP_111702146.1\|971296_971581_-	hypothetical protein	A0A097PAV1	Streptococcus_pyogenes_phage	1.1e-34	84.0
WP_111702147.1\|971577_971991_-	hypothetical protein	Q938M1	Temperate_phage	2.6e-37	66.7
WP_111702148.1\|971987_972272_-	DUF3310 domain-containing protein	A0A1P8VVP5	Streptococcus_phage	1.3e-48	96.8
WP_011018138.1\|972513_972870_-	hypothetical protein	A0A1P8VVP9	Streptococcus_phage	5.0e-61	100.0
WP_023079767.1\|972853_973204_-	VRR-NUC domain-containing protein	A0A1P8VVL5	Streptococcus_phage	9.9e-46	88.5
WP_014635521.1\|973157_974027_-	bifunctional DNA primase/polymerase	A0A1P8BME8	Lactococcus_phage	5.8e-103	65.6
WP_011017876.1\|974295_975849_-	hypothetical protein	A0A1P8BM51	Lactococcus_phage	1.5e-210	70.6
WP_085577342.1\|975866_976349_-	DUF669 domain-containing protein	A0A1P8BM40	Lactococcus_phage	1.7e-59	70.7
WP_111702150.1\|976353_977757_-	DEAD/DEAH box helicase	A0A1P8BMH7	Lactococcus_phage	2.3e-194	72.1
WP_111702151.1\|977792_978476_-	AAA family ATPase	J7KC09	Streptococcus_phage	1.8e-123	97.7
WP_011284877.1\|978472_978757_-	hypothetical protein	NA	NA	NA	NA
WP_002984315.1\|978753_978948_-	hypothetical protein	J7KK69	Streptococcus_phage	3.9e-12	54.2
WP_011284878.1\|978947_979277_-	hypothetical protein	J7KBZ0	Streptococcus_phage	7.9e-13	41.8
WP_011017881.1\|979357_979495_-	hypothetical protein	A0A097PAR2	Streptococcus_pyogenes_phage	3.4e-18	100.0
WP_011017882.1\|979491_979788_-	hypothetical protein	A0A097PAT8	Streptococcus_pyogenes_phage	3.1e-48	98.0
WP_011054585.1\|979866_980052_-	helix-turn-helix transcriptional regulator	A0A1X9I6I3	Streptococcus_phage	3.3e-16	72.1
WP_011284879.1\|980218_980458_+	hypothetical protein	NA	NA	NA	NA
WP_111702152.1\|980606_980831_+	hypothetical protein	NA	NA	NA	NA
WP_038433319.1\|980998_981199_-	helix-turn-helix transcriptional regulator	A0A141E205	Streptococcus_phage	2.1e-08	61.4
WP_111702153.1\|981295_982075_+	hypothetical protein	A0A1S5S7L0	Streptococcus_phage	1.4e-44	51.7
WP_111702154.1\|982208_982367_-	hypothetical protein	J7KH24	Streptococcus_phage	2.2e-21	90.4
WP_014635530.1\|982425_982641_+	hypothetical protein	J7KBX0	Streptococcus_phage	8.8e-29	97.1
WP_038433318.1\|983131_983956_+	helix-turn-helix transcriptional regulator	A0A097PBE5	Streptococcus_pyogenes_phage	8.4e-120	84.8
WP_002984270.1\|983968_984778_+	type II toxin-antitoxin system PemK/MazF family toxin	J7KDP1	Streptococcus_phage	3.8e-24	35.8
WP_011017891.1\|985027_986116_+\|integrase	site-specific integrase	Q38159	Streptococcus_phage	4.2e-204	99.4
WP_002989605.1\|986478_987099_+	DUF3862 domain-containing protein	NA	NA	NA	NA
986159:986257	attR	NA	NA	NA	NA
WP_014407632.1\|987355_989620_-	glycogen/starch/alpha-glucan family phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	1.2e-11	43.7

DBSCAN-SWA_5

1063926 : 1168451

111

Streptococcus_phage(40.0%)

portal,protease,integrase,terminase,holin,tRNA,tail,capsid

attL 1105004:1105023|attR 1146145:1146164

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011184658.1\|1063926_1064622_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_011888802.1\|1064640_1065402_-	DUF3169 family protein	NA	NA	NA	NA
WP_002989220.1\|1065398_1065614_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_020905288.1\|1065974_1068593_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	5.1e-62	34.1
WP_111702179.1\|1068979_1070035_-	peptidylprolyl isomerase PrsA	NA	NA	NA	NA
WP_011017939.1\|1070097_1070805_-	O-methyltransferase	A0A2P1JQT7	Mycobacterium_phage	2.6e-08	27.2
WP_111702180.1\|1070870_1072067_-	OFA family MFS transporter	NA	NA	NA	NA
WP_030127119.1\|1072441_1074247_-	oligoendopeptidase F	NA	NA	NA	NA
WP_111702181.1\|1074259_1075222_-	competence protein CoiA	NA	NA	NA	NA
WP_011528761.1\|1075516_1076233_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_111702182.1\|1076351_1077056_-	glucosamine-6-phosphate deaminase	NA	NA	NA	NA
WP_002983989.1\|1077257_1078286_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_111702183.1\|1078292_1079513_+	DUF3114 domain-containing protein	NA	NA	NA	NA
WP_011017945.1\|1079626_1080217_-	serine hydrolase	NA	NA	NA	NA
WP_010922432.1\|1080213_1080462_-	hypothetical protein	NA	NA	NA	NA
WP_011054657.1\|1080446_1080674_-	hypothetical protein	NA	NA	NA	NA
WP_011017948.1\|1080840_1081446_-	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	1.8e-58	53.2
WP_011017949.1\|1081542_1082583_-	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_111702184.1\|1082653_1084897_-	DNA internalization-related competence protein ComEC/Rec2	M1PSD2	Streptococcus_phage	1.8e-55	59.2
WP_002983967.1\|1084877_1085540_-	ComEA family DNA-binding protein	NA	NA	NA	NA
WP_012560804.1\|1085739_1086480_-	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_014407673.1\|1086519_1087374_+\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
WP_002989164.1\|1087363_1087642_+	GIY-YIG nuclease family protein	W8W2G4	Invertebrate_iridovirus	1.8e-05	36.0
WP_111702185.1\|1087665_1089666_-	potassium transporter Kup	M1IBC2	Acanthocystis_turfacea_Chlorella_virus	5.8e-66	34.0
WP_111702186.1\|1089792_1091412_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.9e-59	36.5
WP_111677347.1\|1091718_1093263_-	peptide chain release factor 3	A0A1B0RXH7	Streptococcus_phage	1.8e-35	29.0
WP_002983946.1\|1093510_1094206_-	TIGR02206 family membrane protein	NA	NA	NA	NA
WP_111677348.1\|1094285_1095677_-	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase	NA	NA	NA	NA
WP_023610118.1\|1095867_1096914_-	D-alanine--D-alanine ligase	NA	NA	NA	NA
WP_011888787.1\|1097014_1097611_-	recombination protein RecR	NA	NA	NA	NA
WP_002989141.1\|1098397_1099177_-	formate/nitrite transporter family protein	NA	NA	NA	NA
WP_002989140.1\|1099300_1099843_-	hypothetical protein	NA	NA	NA	NA
WP_011017960.1\|1100003_1100525_-	transcription repressor NadR	NA	NA	NA	NA
WP_002983928.1\|1100631_1101327_-	phosphoglycerate mutase	NA	NA	NA	NA
WP_010922443.1\|1101565_1102501_+	dihydroorotate oxidase	A0A1V0SH91	Hokovirus	1.3e-65	44.8
WP_002989134.1\|1102555_1102729_-	hypothetical protein	NA	NA	NA	NA
WP_011184725.1\|1102800_1104663_-	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	5.4e-90	33.8
1105004:1105023	attL	NA	NA	NA	NA
WP_011184726.1\|1105192_1105375_-	hypothetical protein	A3F673	Streptococcus_phage	2.0e-21	81.7
WP_011184727.1\|1105614_1106373_+	DNase Mf2	NA	NA	NA	NA
WP_002985327.1\|1106483_1107191_+	streptococcal pyrogenic exotoxin SpeC	A0A097PAT7	Streptococcus_pyogenes_phage	3.9e-09	27.1
WP_023611694.1\|1107259_1108012_-	SH3 domain-containing protein	A3F665	Streptococcus_phage	2.1e-141	97.2
WP_003052353.1\|1108013_1108346_-\|holin	phage holin	A3F664	Streptococcus_phage	5.7e-51	100.0
WP_111694880.1\|1108347_1108677_-	hypothetical protein	A3F663	Streptococcus_phage	6.2e-50	99.0
WP_111702187.1\|1108687_1109305_-	DUF1366 domain-containing protein	Q938J7	Temperate_phage	3.3e-76	87.3
WP_002987513.1\|1109307_1109739_-	DUF1617 family protein	Q938J8	Temperate_phage	1.1e-73	100.0
WP_111674633.1\|1109750_1111634_-	gp58-like family protein	Q938J9	Temperate_phage	8.0e-251	96.5
WP_111702188.1\|1111648_1112668_-	hyaluronoglucosaminidase	Q938K0	Temperate_phage	2.7e-176	96.2
WP_111674635.1\|1112664_1114809_-\|tail	phage tail protein	Q938K1	Temperate_phage	0.0e+00	97.1
WP_111674636.1\|1114805_1115522_-\|tail	phage tail family protein	Q938K2	Temperate_phage	3.6e-135	98.7
WP_111702189.1\|1115518_1118779_-	tape measure protein	Q938K3	Temperate_phage	0.0e+00	98.6
WP_010922087.1\|1118768_1119350_-	hypothetical protein	Q938K4	Temperate_phage	1.6e-104	98.4
WP_010922086.1\|1119353_1119788_-	hypothetical protein	Q938K5	Temperate_phage	2.9e-71	99.3
WP_011054741.1\|1119826_1120312_-	hypothetical protein	Q938K6	Temperate_phage	1.6e-86	100.0
WP_010922084.1\|1120311_1120710_-\|capsid	phage capsid protein	Q79S87	Temperate_phage	3.5e-71	100.0
WP_010922083.1\|1120706_1121063_-	hypothetical protein	Q79S88	Temperate_phage	4.5e-62	100.0
WP_010922082.1\|1121062_1121395_-	hypothetical protein	Q79S86	Temperate_phage	9.6e-59	100.0
WP_111674639.1\|1121384_1121801_-	hypothetical protein	Q938K7	Temperate_phage	1.3e-55	98.2
WP_010922080.1\|1121854_1122673_-\|capsid	N4-gp56 family major capsid protein	Q79S85	Temperate_phage	4.0e-146	100.0
WP_010922079.1\|1122676_1123291_-	hypothetical protein	Q938K8	Temperate_phage	3.1e-95	95.0
WP_010922078.1\|1123416_1123683_-	hypothetical protein	Q938K9	Temperate_phage	8.3e-37	95.5
WP_010922077.1\|1123769_1123997_-	hypothetical protein	NA	NA	NA	NA
WP_111674641.1\|1123996_1125490_-\|capsid	phage minor capsid protein	Q938L1	Temperate_phage	3.1e-213	79.8
WP_111674642.1\|1125494_1126997_-\|portal	phage portal protein	Q938L2	Temperate_phage	9.8e-276	97.2
WP_111702190.1\|1127010_1128222_-\|terminase	PBSX family phage terminase large subunit	Q938L3	Temperate_phage	4.3e-221	97.6
WP_111674775.1\|1128304_1129000_-\|terminase	terminase	A0A2H4J4R0	uncultured_Caudovirales_phage	1.7e-28	34.2
WP_111674644.1\|1129119_1129536_-	transcriptional regulator	A7J289	Streptococcus_phage	7.3e-72	98.6
WP_023611036.1\|1129532_1129724_-	hypothetical protein	NA	NA	NA	NA
WP_023079587.1\|1129972_1130143_-	hypothetical protein	A7J285	Streptococcus_phage	2.8e-22	98.1
WP_047149508.1\|1130143_1131466_-	DEAD/DEAH box helicase family protein	A7J284	Streptococcus_phage	1.1e-249	96.8
WP_011054885.1\|1131462_1131738_-	VRR-NUC domain-containing protein	A7J283	Streptococcus_phage	2.9e-45	96.7
WP_111688312.1\|1132123_1134508_-	DNA primase	A7J282	Streptococcus_phage	8.2e-277	94.6
WP_111674645.1\|1134512_1136435_-	DNA polymerase	A7J280	Streptococcus_phage	0.0e+00	98.4
WP_111674646.1\|1136477_1137041_-	DUF2815 family protein	D2J040	Enterococcus_phage	8.7e-52	59.0
WP_111674647.1\|1137049_1138207_-	DUF2800 domain-containing protein	A7J278	Streptococcus_phage	8.8e-216	97.7
WP_002988708.1\|1138206_1138506_-	hypothetical protein	A7J277	Streptococcus_phage	1.8e-43	100.0
WP_023611025.1\|1138594_1138798_-	hypothetical protein	A7J276	Streptococcus_phage	1.6e-32	98.5
WP_023611032.1\|1139669_1139873_-	hypothetical protein	NA	NA	NA	NA
WP_023611037.1\|1139865_1140036_-	hypothetical protein	A7J273	Streptococcus_phage	2.9e-19	87.5
WP_014411880.1\|1140037_1140349_-	hypothetical protein	A0A1S5SA25	Streptococcus_phage	1.4e-43	78.6
WP_023611028.1\|1140455_1140671_+	hypothetical protein	A0A1S5SA41	Streptococcus_phage	1.9e-15	61.4
WP_023611035.1\|1140644_1140893_-	hypothetical protein	A0A141E1M0	Streptococcus_phage	1.6e-26	69.5
WP_011017885.1\|1140972_1141182_+	hypothetical protein	NA	NA	NA	NA
WP_023611024.1\|1141323_1141584_+	hypothetical protein	M1PS67	Streptococcus_phage	5.8e-27	70.9
WP_023611022.1\|1141682_1142420_-	phage antirepressor KilAC domain-containing protein	A0A2H4IZX7	uncultured_Caudovirales_phage	3.6e-90	68.3
WP_002993390.1\|1142431_1142623_-	hypothetical protein	A7J270	Streptococcus_phage	4.0e-25	92.1
WP_020837421.1\|1143258_1143354_+	type I toxin-antitoxin system Fst family toxin	NA	NA	NA	NA
WP_002994741.1\|1143776_1144124_+	helix-turn-helix transcriptional regulator	A0A1S5SEQ8	Streptococcus_phage	1.2e-40	72.6
WP_002994744.1\|1144127_1144508_+	ImmA/IrrE family metallo-endopeptidase	A0A1S5SFH2	Streptococcus_phage	8.0e-41	61.1
WP_076634078.1\|1144519_1144786_+	DUF4177 domain-containing protein	NA	NA	NA	NA
WP_003051793.1\|1144914_1146057_+\|integrase	site-specific integrase	M1NRJ9	Streptococcus_phage	2.4e-173	77.4
WP_002983920.1\|1146146_1146422_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	2.6e-25	73.0
1146145:1146164	attR	NA	NA	NA	NA
WP_002989129.1\|1146520_1147108_-	YpmS family protein	NA	NA	NA	NA
WP_002992620.1\|1147085_1147928_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_002983913.1\|1147920_1148772_-	DegV family protein	A0A0N9SI50	Staphylococcus_phage	5.4e-13	35.7
WP_111702191.1\|1148987_1149911_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_111702192.1\|1150082_1151744_-	DNA repair protein RecN	NA	NA	NA	NA
WP_111702193.1\|1151765_1152236_-	arginine repressor	NA	NA	NA	NA
WP_111702194.1\|1152222_1153050_-	TlyA family RNA methyltransferase	NA	NA	NA	NA
WP_023612801.1\|1153042_1153915_-	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_002983901.1\|1153914_1154130_-	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_002992349.1\|1154107_1155448_-	exodeoxyribonuclease VII large subunit	A0A1V0SIT1	Klosneuvirus	8.2e-40	30.9
WP_010922486.1\|1155600_1156455_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	2.0e-39	39.8
WP_002989112.1\|1156662_1158357_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	1.6e-128	42.4
WP_111702195.1\|1158534_1159944_-	deoxyribodipyrimidine photo-lyase	A0A1V0SGL1	Hokovirus	4.4e-60	32.8
WP_011888740.1\|1160092_1160827_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-34	38.8
WP_002983887.1\|1160826_1161513_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_002983885.1\|1161639_1161870_-	YkuJ family protein	NA	NA	NA	NA
WP_111702196.1\|1162167_1164450_+\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A2C9CYX3	Yersinia_phage	8.3e-125	39.7
WP_002989103.1\|1164577_1165033_+	NUDIX hydrolase	NA	NA	NA	NA
WP_002983878.1\|1165083_1165386_+	DUF1827 family protein	NA	NA	NA	NA
WP_111702197.1\|1165649_1168451_-\|tRNA	isoleucine--tRNA ligase	A0A1V0SJ93	Klosneuvirus	2.2e-87	27.5

DBSCAN-SWA_6

1211026 : 1289668

Streptococcus_phage(35.59%)

tRNA,integrase,terminase,head,portal,tail,capsid

attL 1236677:1236692|attR 1303300:1303315

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111702211.1\|1211026_1213675_-\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	7.8e-151	40.5
WP_011888719.1\|1213676_1214240_-	AAA family ATPase	NA	NA	NA	NA
WP_002989018.1\|1214840_1215236_-	hypothetical protein	NA	NA	NA	NA
WP_111702212.1\|1215256_1215511_-	DUF1912 family protein	NA	NA	NA	NA
WP_111702213.1\|1215988_1216741_+	3-deoxy-7-phosphoheptulonate synthase	NA	NA	NA	NA
WP_010922517.1\|1216796_1217870_+	3-dehydroquinate synthase	E5ERI4	Ostreococcus_lucimarinus_virus	7.3e-31	31.6
WP_002983743.1\|1218305_1218611_-	cupin domain-containing protein	NA	NA	NA	NA
WP_002983741.1\|1218612_1218951_-	cupin domain-containing protein	NA	NA	NA	NA
WP_002989010.1\|1219003_1219759_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_011018033.1\|1220010_1220889_-	shikimate dehydrogenase	NA	NA	NA	NA
WP_172452973.1\|1221026_1224443_-	glycoside hydrolase family 2 protein	NA	NA	NA	NA
WP_002989005.1\|1224462_1225947_-	response regulator transcription factor	NA	NA	NA	NA
WP_002995648.1\|1225946_1227671_-	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	4.5e-14	24.9
WP_010922522.1\|1227660_1228266_-	YesL family protein	NA	NA	NA	NA
WP_002989000.1\|1228571_1230017_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_111702215.1\|1230097_1231024_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_111702216.1\|1231033_1231984_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_038433514.1\|1232200_1233079_+	ROK family protein	NA	NA	NA	NA
WP_111702217.1\|1233689_1235132_-	glycoside hydrolase family 1 protein	NA	NA	NA	NA
WP_111702218.1\|1235155_1236850_-	beta-N-acetylglucosaminidase domain-containing protein	NA	NA	NA	NA
1236677:1236692	attL	NA	NA	NA	NA
WP_111702219.1\|1236900_1237941_-	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_172452974.1\|1238073_1239360_+	glycoside hydrolase family 125 protein	NA	NA	NA	NA
WP_111702221.1\|1239374_1242080_+	alpha-mannosidase	NA	NA	NA	NA
WP_011285039.1\|1242180_1243536_-	sensor histidine kinase	NA	NA	NA	NA
WP_111702222.1\|1244200_1245556_-	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	1.5e-73	33.0
WP_011184907.1\|1245746_1245929_-	hypothetical protein	A3F673	Streptococcus_phage	4.4e-21	83.3
WP_011285611.1\|1246166_1246967_+	streptodornase Sda3	NA	NA	NA	NA
WP_011017966.1\|1247238_1247673_+	hypothetical protein	NA	NA	NA	NA
WP_011888701.1\|1247722_1248589_-	DUF334 domain-containing protein	Q938J2	Temperate_phage	1.1e-133	99.7
WP_011017840.1\|1248576_1249101_-	DUF4065 domain-containing protein	Q938J3	Temperate_phage	4.0e-99	100.0
WP_111702223.1\|1249240_1250443_-	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	1.6e-241	99.8
WP_011054731.1\|1250553_1250739_-	hypothetical protein	Q938J5	Temperate_phage	1.7e-25	100.0
WP_011054732.1\|1250735_1251032_-	hypothetical protein	Q938J6	Temperate_phage	7.5e-47	100.0
WP_011054733.1\|1251042_1251654_-	DUF1366 domain-containing protein	Q938J7	Temperate_phage	2.7e-91	100.0
WP_002987513.1\|1251656_1252088_-	DUF1617 family protein	Q938J8	Temperate_phage	1.1e-73	100.0
WP_011054734.1\|1252099_1253983_-	gp58-like family protein	Q938J9	Temperate_phage	2.8e-256	100.0
WP_010922091.1\|1253997_1255011_-	hyaluronoglucosaminidase	Q938K0	Temperate_phage	2.0e-184	99.7
WP_111702224.1\|1255007_1257059_-\|tail	phage tail protein	A3F656	Streptococcus_phage	0.0e+00	84.9
WP_011284845.1\|1257055_1257835_-\|tail	phage tail family protein	A3F655	Streptococcus_phage	1.9e-65	54.0
WP_111702225.1\|1257866_1261502_-	tape measure protein	C5IUK3	Streptococcus_phage	3.2e-86	41.4
WP_021340179.1\|1261516_1261813_-	hypothetical protein	A0A0S2MYH1	Enterococcus_phage	1.3e-09	42.2
WP_002990023.1\|1261887_1262241_-	hypothetical protein	Q77RZ7	Lactococcus_phage	5.5e-20	48.6
WP_030126608.1\|1262294_1262918_-\|tail	phage major tail protein, TP901-1 family	D7RWD5	Brochothrix_phage	3.2e-39	50.5
WP_011284850.1\|1262972_1263362_-	hypothetical protein	B5SP36	Lactococcus_phage	4.2e-45	68.2
WP_030126607.1\|1263358_1263724_-	HK97 gp10 family phage protein	A0A097BY98	Enterococcus_phage	5.9e-17	46.3
WP_011284852.1\|1263704_1264013_-	hypothetical protein	A0A2P1JTW8	Anoxybacillus_phage	7.4e-13	40.2
WP_002984392.1\|1264009_1264363_-\|head,tail	phage head-tail connector protein	A0A2H4J002	uncultured_Caudovirales_phage	9.7e-25	49.6
WP_011284854.1\|1264376_1264619_-	hypothetical protein	NA	NA	NA	NA
WP_011284855.1\|1264628_1265711_-\|capsid	major capsid protein	A0A2H4J022	uncultured_Caudovirales_phage	3.4e-105	57.1
WP_011284856.1\|1265713_1266094_-\|head	head decoration protein	A0A0K2CNR0	Brevibacillus_phage	1.8e-05	32.5
WP_023079765.1\|1266103_1266637_-	DUF4355 domain-containing protein	A0A141E0S7	Streptococcus_phage	6.8e-14	80.7
WP_011284858.1\|1266780_1267047_-	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	1.9e-25	70.5
WP_011284859.1\|1267049_1267364_-	hypothetical protein	M1PLI3	Streptococcus_phage	6.8e-38	72.8
WP_002988389.1\|1267433_1267619_-	hypothetical protein	NA	NA	NA	NA
WP_012560958.1\|1267622_1269185_-\|head	phage head morphogenesis protein	U6E9F1	Streptococcus_phage	2.5e-48	44.2
WP_002984369.1\|1269165_1270668_-\|portal	phage portal protein	C9W9H5	Streptococcus_virus	1.9e-141	54.5
WP_020833530.1\|1270679_1271987_-\|terminase	PBSX family phage terminase large subunit	A0A2H4IYR5	uncultured_Caudovirales_phage	2.0e-184	75.7
WP_047235590.1\|1271964_1272432_-\|terminase	terminase small subunit	A0A141E1Y3	Streptococcus_phage	1.9e-52	70.8
WP_001132273.1\|1272494_1272680_+	type II toxin-antitoxin system HicA family toxin	D6PSW1	Lactobacillus_phage	1.7e-09	54.0
WP_002987543.1\|1272731_1273109_+	type II toxin-antitoxin system HicB family antitoxin	I3NLB2	Bifidobacterium_phage	3.3e-15	44.0
WP_002990048.1\|1273424_1273637_+	hypothetical protein	NA	NA	NA	NA
WP_011284864.1\|1273726_1274641_-	hypothetical protein	NA	NA	NA	NA
WP_111702226.1\|1275115_1275550_-	ArpU family transcriptional regulator	J7KDQ1	Streptococcus_phage	2.6e-72	96.5
WP_172452975.1\|1276024_1276192_-	hypothetical protein	NA	NA	NA	NA
WP_111702227.1\|1276188_1276740_-	DUF1642 domain-containing protein	A0A1S5PS22	Streptococcus_phage	1.9e-11	33.0
WP_111702372.1\|1276752_1277451_-	site-specific DNA-methyltransferase	A0A1S5SBM4	Streptococcus_phage	9.3e-104	76.3
WP_111702228.1\|1277457_1277742_-	hypothetical protein	A0A097PAV1	Streptococcus_pyogenes_phage	1.0e-37	89.4
WP_111702229.1\|1277738_1277915_-	peptide chain release factor 2	NA	NA	NA	NA
WP_111702230.1\|1277928_1278198_-	hypothetical protein	A0A1P8VVR6	Streptococcus_phage	7.6e-46	96.6
WP_011054755.1\|1278194_1278479_-	DUF3310 domain-containing protein	Q938M3	Temperate_phage	5.4e-50	100.0
WP_011054756.1\|1278472_1278724_-	hypothetical protein	Q938M4	Temperate_phage	6.8e-41	100.0
WP_011054757.1\|1278720_1279077_-	hypothetical protein	A0A1P8VVP9	Streptococcus_phage	1.6e-51	85.6
WP_011054758.1\|1279073_1279514_-	RusA family crossover junction endodeoxyribonuclease	A0A097PAS0	Streptococcus_pyogenes_phage	8.5e-79	97.3
WP_011106686.1\|1279513_1279717_-	hypothetical protein	Q938M6	Temperate_phage	4.7e-32	100.0
WP_032464069.1\|1279722_1280142_-	single-stranded DNA-binding protein	Q938M7	Temperate_phage	2.4e-70	99.3
WP_011054760.1\|1280134_1280809_-	ERF family protein	Q938M8	Temperate_phage	2.5e-106	100.0
WP_011018142.1\|1280809_1281292_-	siphovirus Gp157 family protein	Q938M9	Temperate_phage	8.2e-51	100.0
WP_011018143.1\|1281313_1281568_-	hypothetical protein	Q938N0	Temperate_phage	3.7e-42	98.8
WP_011285579.1\|1281548_1281902_-	hypothetical protein	A0A097PAU3	Streptococcus_pyogenes_phage	2.8e-16	54.0
WP_011888684.1\|1282042_1282825_-	ATP-binding protein	A0A097PAQ0	Streptococcus_pyogenes_phage	1.0e-143	97.3
WP_021340639.1\|1282811_1283615_-	DnaD domain protein	A0A2P0VI76	Streptococcus_phage	2.4e-63	53.8
WP_012560973.1\|1283730_1284174_-	hypothetical protein	NA	NA	NA	NA
WP_000568478.1\|1284229_1284610_+	hypothetical protein	NA	NA	NA	NA
WP_000370473.1\|1284599_1284872_-	hypothetical protein	NA	NA	NA	NA
WP_012560974.1\|1285044_1285224_-	hypothetical protein	A0A1X9I5M8	Streptococcus_phage	1.2e-12	65.5
WP_023611247.1\|1285519_1285771_-	transcriptional regulator, AlpA family	A0A1P8VVV6	Streptococcus_phage	7.6e-40	94.0
WP_023612341.1\|1285870_1286089_-	helix-turn-helix transcriptional regulator	A0A1P8VVR5	Streptococcus_phage	5.9e-33	97.2
WP_023611288.1\|1286276_1286636_+	helix-turn-helix transcriptional regulator	A0A1P8VVN3	Streptococcus_phage	1.7e-56	95.0
WP_032467159.1\|1286619_1286997_+	ImmA/IrrE family metallo-endopeptidase	A0A1P8VVK5	Streptococcus_phage	4.3e-55	79.2
WP_111687984.1\|1287277_1288321_+	DUF4041 domain-containing protein	M1NRY5	Streptococcus_phage	4.2e-108	77.3
WP_011018152.1\|1288501_1289668_+\|integrase	tyrosine-type recombinase/integrase	C5J953	Streptococcus_phage	2.4e-80	42.4
1303300:1303315	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LS483399

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection