CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483412	Legionella pneumophila subsp. pascullei strain NCTC12272 chromosome 1	1 crisprs	csa3,DEDDh,DinG,cas3,WYL	0	8	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483412_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483412_1

513743-514254

Orphan

Consensus_repeat	Method
GCAAAAGATCTAAAAGACGCTGGTTTTTCTGC	CRISPRCasFinder

8 spacers

The CRISPR arrays of NZ_LS483412_1

>merge|NZ_LS483412|1|513743-514254|CRISPRCasFinder
GCAAAAGAGCTGAAAGATGCCGGGTTTACTGCAGCTGAGTTAAAAGCGGCCGGTTTTAGTGCTAAAGACTTAAAAGACGCCGGTTTTACAGCAAAGGAATTGCGTGATGCGGGATTCTCCGCTCAGGAATTAAAAGATGCTGGTTTTAGCGCAAAAGATCTAAAAGACGCTGGTTTTTCTGCTGCAGAATTAAAAGCAGCTGGATTTACAGCAGCACAGCTCAAGGCCGCTGGGTTTTCTGCAAAAGATCTAAAAGATGCTGGTTTTTCTGCCGCAGAGTTAAAAGCAGCAGGATTTGACGCAAAAGAATTGAAAGATGCTGGTTTTTCTGCTGCAGAATTAAAAGCAGCCGGATTTAGCGCAAAAGAATTGAAAGATGCTGGTTTTAGTGCCTCGGATTTGAAAAACGCAGGGTTTAGTGCCTCAGAATTAAAGAATGCTGGATATTCTGCCGACGAGCTAAAAAAAGCAGGATATACCTCAGCTGAACTGAGAAATGCTGGTTTTTCTCC

>NZ_LS483412|1|1|513743-514254|CRISPRCasFinder
GCAAAAGAGCTGAAAGATGCCGGGTTTACTGC	AGCTGAGTTAAAAGCGGCCGGTTTTAGT
GCTAAAGACTTAAAAGACGCCGGTTTTACAGC	AAAGGAATTGCGTGATGCGGGATTCTCC
GCTCAGGAATTAAAAGATGCTGGTTTTAGCGC	AAAAGATCTAAAAGACGCTGGTTTTTCT
GCTGCAGAATTAAAAGCAGCTGGATTTACAGC	AGCACAGCTCAAGGCCGCTGGGTTTTCT
GCAAAAGATCTAAAAGATGCTGGTTTTTCTGC	CGCAGAGTTAAAAGCAGCAGGATTTGAC
GCAAAAGAATTGAAAGATGCTGGTTTTTCTGC	TGCAGAATTAAAAGCAGCCGGATTTAGC
GCAAAAGAATTGAAAGATGCTGGTTTTAGTGC	CTCGGATTTGAAAAACGCAGGGTTTAGT
GCCTCAGAATTAAAGAATGCTGGATATTCTGC	CGACGAGCTAAAAAAAGCAGGATATACC
TCAGCTGAACTGAGAAATGCTGGTTTTTCTCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483412.1\|WP_027223521.1\|510041_510326_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378659
NZ_LS483412.1\|WP_027223530.1\|521088_522345_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340927
NZ_LS483412.1\|WP_027223520.1\|509460_510030_+\|OmpA-family-protein	unknown	unknown	gnl\|CDD\|143586
NZ_LS483412.1\|WP_027223526.1\|516040_516625_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483412.1\|WP_027223533.1\|526323_527913_-\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
NZ_LS483412.1\|WP_027223531.1\|522347_525269_-\|type-VI-secretion-protein-IcmF	unknown	unknown	gnl\|CDD\|274531
NZ_LS483412.1\|WP_014843348.1\|503927_504272_+\|Dot/Icm-secretion-system-substrate-recognition-protein	unknown	unknown	gnl\|CDD\|289381
NZ_LS483412.1\|WP_027223516.1\|504371_504734_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483412.1\|WP_027223525.1\|515223_516033_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227278
NZ_LS483412.1\|WP_027223517.1\|504824_505400_+\|Dot/Icm-secretion-system-protein-IcmQ	unknown	unknown	gnl\|CDD\|286550
NZ_LS483412.1\|WP_027223519.1\|506713_509065_+\|TraM-recognition-domain-containing-protein	unknown	unknown	gnl\|CDD\|274760
NZ_LS483412.1\|WP_027223529.1\|517909_520939_+\|type-IV-secretion-protein-IcmB	unknown	unknown	unknown
NZ_LS483412.1\|WP_027223532.1\|525268_526054_-\|DotU-family-type-IV/VI-secretion-system-protein	unknown	unknown	gnl\|CDD\|274532
NZ_LS483412.1\|WP_027223527.1\|516649_517048_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483412.1\|WP_027223523.1\|510981_512064_+\|type-IV-secretion-protein-IcmK	unknown	unknown	gnl\|CDD\|372018
NZ_LS483412.1\|WP_027223515.1\|503280_503493_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483412.1\|WP_027223534.1\|527939_528809_-\|50S-ribosomal-protein-L11-methyltransferase	unknown	unknown	gnl\|CDD\|283886
NZ_LS483412.1\|WP_027223522.1\|510340_510979_+\|type-IVB-secretion-system-apparatus-protein-IcmL/DotI	unknown	unknown	gnl\|CDD\|378659
NZ_LS483412.1\|WP_027223518.1\|505586_506717_+\|type-IVB-secretion-system-coupling-complex-protein-DotM/IcmP	unknown	unknown	unknown
NZ_LS483412.1\|WP_027223528.1\|517247_517874_+\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|214702

Protein	Function_ID	Function_description	E-value
NZ_LS483412.1\|WP_027223521.1\|510041_510326_+\|hypothetical-protein	gnl\|CDD\|378659	pfam11393, T4BSS_DotI_IcmL, Type-IV b secretion system, inner-membrane complex component. IcmL contains two amphipathic beta-sheet regions, required for the pore-forming ability which may be related to the transfer of this protein into a host cell membrane. The icmL gene shows significant similarity to plasmid genes involved in conjugation however IcmL is thought to be required for macrophage killing. It is unknown whether conjugation plays a role in macrophage killing. This is a family of DotI/IcmL proteins of type IVb secretion systems, that reside in the inner-membrane. It carries a single transmembrane helix in the N-terminal conserved region, has an extra-periplasmic domain, and is conserved in all T4BSSs including I-type conjugation systems (TraM). DotI/IcmL (and DotJ) may form an inner membrane complex that associates with the core complex.	1.93473e-07
NZ_LS483412.1\|WP_027223530.1\|521088_522345_-\|MFS-transporter	gnl\|CDD\|340927	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli shikimate transporter (ShiA), inner membrane metabolite transport protein YhjE, and other putative metabolite transporters. ShiA is involved in the uptake of shikimate, an aromatic compound involved in siderophore biosynthesis. It has been suggested that YhjE may mediate the uptake of osmoprotectants. The ShiA-like subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.63435e-101
NZ_LS483412.1\|WP_027223520.1\|509460_510030_+\|OmpA-family-protein	gnl\|CDD\|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	2.98745e-17
NZ_LS483412.1\|WP_027223533.1\|526323_527913_-\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NZ_LS483412.1\|WP_014843348.1\|503927_504272_+\|Dot/Icm-secretion-system-substrate-recognition-protein	gnl\|CDD\|289381	pfam12608, T4bSS_IcmS, Type IVb secretion, IcmS, effector-recruitment. This is a family of Gram-negative bacterial proteins involved in the Dot/Icm type IVb transport system. Members are small acidic cytoplasmic proteins required for Dot/Icm-dependent activities. Binary complexes of IcmW-IcmS and of IcmS-LvgA have been consistently reported, suggestive of the binary WXG100 system. The IcmW-IcmS complex may play a role in recruitment of effector proteins to the transport apparatus.	9.24554e-42
NZ_LS483412.1\|WP_027223528.1\|517247_517874_+\|HNH-endonuclease	gnl\|CDD\|214702	smart00507, HNHc, HNH nucleases.	3.61592e-05
NZ_LS483412.1\|WP_027223525.1\|515223_516033_+\|hypothetical-protein	gnl\|CDD\|227278	COG4942, COG4942, Membrane-bound metallopeptidase [Cell division and chromosome partitioning].	0.00239718
NZ_LS483412.1\|WP_027223517.1\|504824_505400_+\|Dot/Icm-secretion-system-protein-IcmQ	gnl\|CDD\|286550	pfam09475, Dot_icm_IcmQ, Dot/Icm secretion system protein (dot_icm_IcmQ). Proteins in this entry are the IcmQ component of Dot/Icm secretion systems, as found in the obligate intracellular pathogens Legionella pneumophila and Coxiella burnetii. While this system resembles type IV secretion systems and has been called a form of type IV, the literature now seems to favour calling this the Dot/Icm system. This protein was shown to be essential for translocation.	5.67282e-101
NZ_LS483412.1\|WP_027223519.1\|506713_509065_+\|TraM-recognition-domain-containing-protein	gnl\|CDD\|274760	TIGR03743, SXT_TraD, conjugative coupling factor TraD, SXT/TOL subfamily. Members of this protein family are the putative conjugative coupling factor, TraD (or TraG), rather distantly related to the well-characterized TraD of the F plasmid. Members are associated with conjugative-transposon-like mobile genetic elements of the class that includes SXT, an antibiotic resistance transfer element in some Vibrio cholerae strains. [Mobile and extrachromosomal element functions, Other].	7.11441e-08
NZ_LS483412.1\|WP_027223532.1\|525268_526054_-\|DotU-family-type-IV/VI-secretion-system-protein	gnl\|CDD\|274532	TIGR03349, IV_VI_DotU, type IV / VI secretion system protein, DotU family. At least two families of proteins, often encoded by adjacent genes, show sequence similarity due to homology between type IV secretion systems and type VI secretion systems. One is the IcmF family (TIGR03348). The other is the family described by this model. Members include DotU from the Legionella pneumophila type IV secretion system. Many of the members of this protein family from type VI secretion systems have an additional C-terminal domain with OmpA/MotB homology. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	2.03916e-47
NZ_LS483412.1\|WP_027223534.1\|527939_528809_-\|50S-ribosomal-protein-L11-methyltransferase	gnl\|CDD\|283886	pfam06325, PrmA, Ribosomal protein L11 methyltransferase (PrmA). This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.	7.56629e-104
NZ_LS483412.1\|WP_027223523.1\|510981_512064_+\|type-IV-secretion-protein-IcmK	gnl\|CDD\|372018	pfam12293, T4BSS_DotH_IcmK, Putative outer membrane core complex of type IVb secretion. T4BSS_DotH_IcmK is a family of bacterial transporter proteins from Proteobacteria. DotH is an integral outer membrane component and it may form an outer membrane complex along with DotD and DotC functionally equivalent to secretins. DotH is the strongest candidate for the VirB9 counterpart of other T4BSS systems.	2.07633e-120
NZ_LS483412.1\|WP_027223531.1\|522347_525269_-\|type-VI-secretion-protein-IcmF	gnl\|CDD\|274531	TIGR03348, VI_IcmF, type VI secretion protein IcmF. Members of this protein family are IcmF homologs and tend to be associated with type VI secretion systems. [Cellular processes, Pathogenesis].	5.56606e-118
NZ_LS483412.1\|WP_027223522.1\|510340_510979_+\|type-IVB-secretion-system-apparatus-protein-IcmL/DotI	gnl\|CDD\|378659	pfam11393, T4BSS_DotI_IcmL, Type-IV b secretion system, inner-membrane complex component. IcmL contains two amphipathic beta-sheet regions, required for the pore-forming ability which may be related to the transfer of this protein into a host cell membrane. The icmL gene shows significant similarity to plasmid genes involved in conjugation however IcmL is thought to be required for macrophage killing. It is unknown whether conjugation plays a role in macrophage killing. This is a family of DotI/IcmL proteins of type IVb secretion systems, that reside in the inner-membrane. It carries a single transmembrane helix in the N-terminal conserved region, has an extra-periplasmic domain, and is conserved in all T4BSSs including I-type conjugation systems (TraM). DotI/IcmL (and DotJ) may form an inner membrane complex that associates with the core complex.	1.19468e-86

>NZ_LS483412.1|WP_027223523.1|510981_512064_+|type-IV-secretion-protein-IcmK
MKKHYQLCKYCLVISLTFSMSCSVYAADQSDDAQQALQQLRMLQQKLSQNPAPDVQLGTGDGGDNAASDGTQQSNQAGQTNTPAANQTANAGGEGQIISQDDAEVIDKKAFKDMTRNLYPLNPEQVVRLKQIYETSEYAKAATPGTPPKPTATSQFVNLSPGSTPPVIRLSQGFVSSLVFLDSTGAPWPIAAYDLGDPSSFNIQWDKTSNTLMIQATKLYNYGNLAVRLRGLNTPVMLTLIPGQKAVDYRVDLRVQGYGPNAKSMPTEEGIPPSANDLLLHVLEGVPPPGSRRLVVSGGDARAWLSNEKMYVRTNLTILSPGWLASMTSADGTHAYEMQKSPVLLVSWHGKVMQLKVEGL
>NZ_LS483412.1|WP_027223522.1|510340_510979_+|type-IVB-secretion-system-apparatus-protein-IcmL/DotI
MAEDALTVVALRNKFYKDSQRKVILALLIAILVNVVLASLVVYMITHPPAPKYFATSINGRITPLFPLDEPNQSDSAVLQWANQAAIAAFTYNFVNYRDELQASSGFFTAEGWDQFLGALEQSNNLDAVKAKKLVVSAVATRAPIILQKGVLNGRYSWRVQMPILVTYQSASEFTQQNNVVTMLITRVSTLNSPRGIGISQFVVGPASGGVS
>NZ_LS483412.1|WP_027223521.1|510041_510326_+|hypothetical-protein
MSRETWALIKRNKNFNVHIYRRGLTLLILSLGLNCGLSGLIYYVHMHEPERDFYATSGITPPIQLKPMSTPNMSSQALLPPDPPDDDSQRIIPQ
>NZ_LS483412.1|WP_027223520.1|509460_510030_+|OmpA-family-protein
MRSLRTNYIYVLFKTTGLFFLLFLSACHRSGYIPENEVPKLPCRVDGACDATIIKMMTDLNKKGIKVASVGQNYLISIPASALFADQSPRLHWASYSLLNEIATFLKQFRKIAITVTSYSSKYVSVKRERALTLARSRVVSEYLWSQGVDSRIIFTQGLGSDKPITSYTLGGDRSPNARVEITFRRAVA
>NZ_LS483412.1|WP_027223519.1|506713_509065_+|TraM-recognition-domain-containing-protein
MMRGIDSRHELDPTLLLRDTRTFTQRLADFFADPTNISIVLISLAAVSYYFSESATFLLIMGGIFFLYSYTRKQKLPFRLPQISRAKDYNDLKPGINKPNIARGITFFGNDRKTGEELWFANDDMRTHALIFGSTGSGKTETLVSLSYNALVQGSGFIYVDGKGDNSLYAKVFSMVRSMGREDDLLLINFMTGARDIVGPQEKRLSNTLNPFCQGSSSMLTQLVVSLMGSSGQSSDGDMWKGRAIAFVEALMRLLVYMRDEGAILLDANTIRNYFDLQRLESIVIDKVFPRDDQESVNIETIPKLVTDPLRNYLNTLPGYNKEKKGKQVSQVLEQHGFITMQLVRSFSSLADTYGHIIRTNLAEVDFKDVVLNRRILVVLLPALEKSPDELSNLGKIIVSSLKAMMAAGLGEEVEGDYRDVILRKPTNAPTPYMCILDEYGYYAVQGFAVVPAQARSLGFSAIFAGQDLPAFQKASKEEAASIGANTNIKICMKLEDPTETWDFFTKTAGEAYVTKVDSFQTKETSIANSYMDTKSSSFEKRARVDLLDLKEQTEGEAHIFFKSKIVRARMFYANPKPVKQLKINQFLKVEPPPDDYLMKLQKQLASFQSILESGDLSINKTVENEEITLISKALKESTIVEPIERGVAALIAFHGQNEPEPVEDIVEEEVEGALTIFSKLRIDPDAPPILVADKEAFSEPLLPINETRNQMITIERLAGAKDKYAGTVANELIKDFQIATSYPPEERDVIDNQELTDIIRDLSAKISAEREKANKKAAEELT
>NZ_LS483412.1|WP_027223518.1|505586_506717_+|type-IVB-secretion-system-coupling-complex-protein-DotM/IcmP
MAQQQQQSGSDNSMAPVWIVILLFITAYFIWALAHQYIVSFVFTINIWQARLVNLFLNNQLLANQIYLMQTLDPNTVNWDQMVTVMRAVGDYMRYPVICILVVLAFVLYNSNVTLKYRKTYDMKSLRAQEQFNWPAIMPIIKEDLVSQDINKGPWAMALTPMEFARKYNLLRKDDALLDNPVPGEEMTAGIRRGDAKRVFTMQLGPYWDGFERCSPQAYALSAVFMARMNRDRDAANNILKVLDKTFVDGKPDFSVARPVMKKYQNTELVQEVVAKHAYVLTVIASLLEAAREDGVVPSSEFLWLKPVDRRLWYMLNCVGRQTPYSEVAGPFAHWKAEKEMGRRSLVPMIDEAIRALEIAVKEVKLSPRQMEELEP
>NZ_LS483412.1|WP_027223517.1|504824_505400_+|Dot/Icm-secretion-system-protein-IcmQ
MKDQLSDEQKETILKALNDAIEKGPWDKSNFLRVIGKKLIAIRDRFLKRIGAASQAKLKAESHLANRIALRSGQQEIYVSLYSSDGSNIQSWEKIVGSLPRQMISRPIYADEEDIKAVLKTKENKQNEAYVSIYINQSDILHLSADKAPVDKLGKPLLTLKDKSISLENISRFVHVTGVYRYSNGRLIKNG
>NZ_LS483412.1|WP_027223516.1|504371_504734_+|hypothetical-protein
MGNNTDDSARNPFGFYTPPRVKEIGETDVTDATLDSVYSEIISPVKDCILTVAKAVSFNPGGKDNTDAVEVLTELNTKVERAALNQPGLTTKTERMFGATEPEKSSEQPSHEERGFKLSS
>NZ_LS483412.1|WP_014843348.1|503927_504272_+|Dot/Icm-secretion-system-substrate-recognition-protein
MERDISKCMAKIAASMNAKFYLNDRFVSFDEVFSETGLLPAIAKRADQLCSLCLGYGLGATYDEAEGALLGIRVVFDEVTPNVLRLLCMTDVMNELIQGGPSRDYTPLDELMYD
>NZ_LS483412.1|WP_027223515.1|503280_503493_+|hypothetical-protein
MDIHSTYKMLAKMQGNKELSSHKIAETEQTEADTVPQLKLQAEPEAKPDMQNILSNMLGISSNKKHSPMD
>NZ_LS483412.1|WP_027223525.1|515223_516033_+|hypothetical-protein
MMAEHDQNNDEYKFAELDSYDMDQAGESDLDSQASFQSGKEGLTKKKDIKRNALIAIGVVIFIMVMYKIIGWMFFSDKSKQVTSQPAIPPVTQVATPQPVQTIPTTTPIQQVQPTTIVEDDSDLKKKVSAIEMTQQSLRSEVTALSEQINAVNNNIKNLNAQIVNLNQIIGNMSNQIARQSEVINVLMVRTTPKKVVKISRPTVAARVIYYIQAVIPGRAWLIGSNGSTLTVREGSKIPGYGIVKLIDSLQGRILTSSGQVIKFSQEDS
>NZ_LS483412.1|WP_027223526.1|516040_516625_+|hypothetical-protein
MADPTCTGGTVSCWIVSQANILANVANQLEPVQRLITGGAYLIGCAFIFKAIYSLKVYGEARTMMSSNTSIKEPVMYLLVGALLIYFPSLVSSVLQTTFGYSSPLAYSGGVSSGSDTITALFGSGSLVGRPLVMIIRVIGLIAFVRGWVLIARSASQGQPPGGTGKGLIHVFGGILAINIVGTIDMINNTLYGT
>NZ_LS483412.1|WP_027223527.1|516649_517048_+|hypothetical-protein
MNIKVIHKSGYKHWLVSAVCLALLTLICQDAAAGVSLGKMASQITGSFTSLTKLITAGSYLAGLGFSIGAIMKFKQHKDNPTQIPIGTPIALIFIAAALLFLPSILGVAGVTMFGGSGGKTAGPTGTIYKTN
>NZ_LS483412.1|WP_027223528.1|517247_517874_+|HNH-endonuclease
MADNQQRCELKLIASPGSWRLYSARKIDERFKSYEQKIFQRDRFTCQFCGFQARLYQDIVNLDGDYTNNRLSNLVTACCFCAQCFFVESVGVGGYGGGTLIYLPELTQAELNSLCHVLFCAITNDTGYKSSAQNIYRSFKFRSQIVEEKFGEGTSDPAIFGQLMIDSGVNSEEIRQKLFKNIRLLPSRAKFRKQIEKWAASALEEIAD
>NZ_LS483412.1|WP_027223529.1|517909_520939_+|type-IV-secretion-protein-IcmB
MANWSESFFEGVDTFFAWLSTSLKQTTESYIDLETADSPTVLVNHDGSLLSILKIEGITGLAGPEEFERLVEGLANSFQAAMGRPGHALQVYFSHDKQNIVKMIKDIYDPAEATANRLELNLRDLFEERVNYLSQYCAEERVYFVLYTRPFNLASDQLKAANKAKMKMIKDTKAPPFKNSQTIFAAVPEIRDTHDAYVRAILNDLDALNVIAKLLEVHDAVHAIRMTGDPDYTADDWRATLPGDKISVRELNNFEGDPSDLLWPPLSKQVLPRDAEIIDLRTVRVGDKIYASTYIDLFPKDVRPFISLFSRILPSHVPWKISFLLESEGLSTIKLKGLLAAILSFSSAQNRLISDSVNLLKYIQLNTDEAIVRLRVVATTWAPEGNIPLLRRRSSELVKAIEGWGSTDVSEICGDPFAGFVSSMLATTLNSSAVASVAPLSDVISMLPITRPASPWKTGALLFRTPDGKPWPFQPGSTEQTTWIDLVYARPGSGKSVLSNALNLALCLSGGLMRLPRIAIIDIGPSSSGLISLLKEALPASKRHLVAYHRLRMTPDYSINPFDTQLGCRYPTALERSFLVNFMTLLTTPLGAAKPYDGMADLAGMVVDELYKSLADEFNPTPYAPGIEEFIDSILEEIGFVRDAKSTWWEVTDALYSAGFVHEAMLAQRYAMPLLADAASICRTPSIEDLYEKITAPTGESLINAFSRMISSAVREYPILSRVTSFDIGDARVVSLDLDEVAKSGGDAADRQTAVMYMLARYVLARHYYLTEESLNNVPEQYKEYHKQRVLEIREDHKRIVYDEFHRTAKSSAVREQVIIDMREGRKWKVQISLLSQAVDDFDPVMIDFATAIYVMDAGPSQAVEKTSQIFGLSETAKIALRTRVHGPRQGGATFLAQFATKTGINVQLLTLTLGPVELWAFSTTAEDATVRNLLYRHLGPSEARRLLAALFPNGTVTKELEARLASMKQKVGLIEDDEREGMINQLVNDILEAYSKDPNVKSLPAKVG
>NZ_LS483412.1|WP_027223530.1|521088_522345_-|MFS-transporter
MKQNTKHSIIAGLYGNALEWYDFLLYASFAPVFAEIFFPSKIHFVSLIATFSLFAIGFIMRPIGGLLLGHYADHVGRRKALILSMSVMTISTALIAVLPDFNSWGIIAPILFSVLRLIQGLAVGGELPGSTTYLIEHMFQNRRGLAGSLVLSSAFLGIFIGALTASIFSTLFTGDSLLNWGWRYAYLLGGILGILGIYLRIKSFESPTFLKDKHTTKLPAKVVFTQFKQQLFLSVIITSILAMANYVLIAYVTTFLVKSEYFLLKDALLINLIALALLTVLIPLMGFLSDAVGRKPIFLIGLFSLSILIFPFFWLLLSGSWWIALCCELLLALVLAPINATVPTIIAEMFPTSVRASGISISYNIGQALFGGTMPLVAFTLIELSNNKMAPAWYLFLWILIVIPITISIRESYQKELI
>NZ_LS483412.1|WP_027223531.1|522347_525269_-|type-VI-secretion-protein-IcmF
MDNSLRALCDAIKKILSQLKPQVNQLSFIIITGKNAQGKSALLKQSNMEEMPVFSEEHAKLYFNQKGIIVELGENWLTNSKTLLLTTLKQLNKCNRHLKITGLILCVDVNDLLIAEPAQFTEQKKSHLQLLQRLGVNLGYQAELALIFTKMDTLAGFSEFYQMDHVNDLSKPLGFSLDCVNQPSKKIETYSLQFNQLIEALGQQVINKMHPVRSTIKRSLIREFPMQLASLRAPIQSLIQGISPKLFHVHSIFFTSAQQGGVSIDRLNKKIQHEYALVVQDTFPQATNFRSYFVEGALKTIQEQCVQIPQVTKFSQRPFIAVAVSLAGLSLLTLSYNHYKTSHILDEASKELLAYEALNNQGTSGAQALYHLSQAANKMNHITSNSISLPTVHQLKLNLQNNTQNRLQGEFLPSLANELEQVITNPGNTPITRYKALKIYLMLGQAKYFSAQPILDWFQQQWKGHASGTIQKQLALLKQTLNNPPQNIPIKSQVISDARNYLNALPTSYLYYSIAKEYFPQEKQKIVIEGFTLPTDEVPTYFTKTGFTKTINDLPKITNTLQSENWVLARQDLSQLHNMLIQAYCFDYVTWWQTFMKKSQPLRYQDYQQGRQLTKLIQQSNSFYKFANLIQQETKPDLTEGISTFNQFIANQFTDLNLTTLSSIKELDLRISELERFIATLSVVNDGGKTAFTITRSRFINDNSSDPVSLLYSQARQLPEPLSSWTRQIAGDAWVILIRDSRQFINNQWQKTVYREFQNSIAKRYPFDSSQTAEIDIADFNRFFSTHGLLNTYSEQYIKPFLDTSSPEWKPKAVNDFILPISNEVIDELIRANIITNMFFPDHSDESKIDFSLQKISLDPVVSNLVLEIGGTKLMDNQTSDSLIRFTWPQNNAKLALDSIEGNHYELTEHGTWAIFKLLEKVNVLVDEQDSSSLQILFEVNSNSGRYLLKTNNQINPFTPGILNGFTLNDHIA
>NZ_LS483412.1|WP_027223532.1|525268_526054_-|DotU-family-type-IV/VI-secretion-system-protein
MTTEQYPSSLVNRLAITEPALVPSGYYRSKLFIAPFSTNILVAAAGPLLSLLERLCLSPSLPPVEDIRENIQHELRAFHSKLDASKYPLDIISIAQYLLSATIDEILGKSYLRVYNLTTEFKSFTPLSSDGAQPQQRFFEILNYIKERPNQFLDLIELTYFCLIAGFEGEYHLKADGRQSLDNTIEDLYQIIQKYRFNKPHRLFNENPLPKTIKKNYKATWITTIGAAGIVILAFVTSHVLLENKAKTVLFGHTQLAMLEN
>NZ_LS483412.1|WP_027223533.1|526323_527913_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MAKKQIYSSFKPRRALLSVSDKRGIKELGQALHDHGVELIATGNTAAMLREHQLPVTDVSDCTGFPEIMDGRVKTLHPAIHAGLLARGEQDSPVLKQHGIKPIDLLIVNLYPFEQVINHPDCDFNKAIENIDIGGPTMVRAAAKNHAHAYVIVDPNDYPKLIHYLQDEKAPSHWSFTLAKKAFAHTAAYDAAIANYLTTLDNDYVPTGFPNVLTCQFNKITELRYGENPHQQAIFYADKNSHPGSLGTATLLQGKQLSYNNILDADAALDCVKSFSNEKSVCVIVKHTNPCGIALSDTSLDAYLKAFQSDPISAYGGIIAFNGTLDSDTAKAILEKQFVEVIIAPDANEEAKKILAAKENIRVLLTGFWQQGTHFRLNMKKVDGGLLVQEHDSLSLESCELQTVTQIKPSDHQLQNLMFAWLAAKHVKSNAIVYAKDLATIGIGGGQTSRVMSARIGLWQAEQMGFDPKGSVMASDAFIPFPDTVEIAAKAGISAIIQPGGSIRDEQIISCADQHKMAMIFTGIRHFKH
>NZ_LS483412.1|WP_027223534.1|527939_528809_-|50S-ribosomal-protein-L11-methyltransferase
MWFQLKIEHCPNDKIEEITEELEEYGALSIMLTDKNDNPVLEPEPGTTPLWPEVIIHALFAQAEEVQYTRKQLVAKRPSLHCSLETLPDKNWERAWMEDFKPHRFGNRLWVCPTWLTPPEPDAVNLMLDPGLAFGTGTHATTSLCLTWLEQADLKNKSIIDYGCGSGILSLAAIKLGAKHVYAVDIDNQALQATQNNAHVNHIKENQLSISSPEALQNPVNLIIANILLAPLISLKERFHQLLPSGAHLVTSGILEEQAPLLIEAYDSAFTHISTEYYEGWALLVFTSK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LS483412_1	1.1\|513775\|28\|NZ_LS483412\|CRISPRCasFinder	513775-513802	28	MH617420	Microviridae sp. isolate ctda655, complete genome	2114-2141	4	0.857
NZ_LS483412_1	1.2\|513835\|28\|NZ_LS483412\|CRISPRCasFinder	513835-513862	28	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	1112477-1112504	4	0.857
NZ_LS483412_1	1.1\|513775\|28\|NZ_LS483412\|CRISPRCasFinder	513775-513802	28	KX513870	Human gut gokushovirus isolate SH-CHD7, complete genome	3712-3739	5	0.821
NZ_LS483412_1	1.5\|514015\|28\|NZ_LS483412\|CRISPRCasFinder	514015-514042	28	MN694311	Marine virus AFVG_250M573, complete genome	10970-10997	5	0.821
NZ_LS483412_1	1.5\|514015\|28\|NZ_LS483412\|CRISPRCasFinder	514015-514042	28	MH572400	Microviridae sp. isolate SD_SF_26, complete genome	1865-1892	5	0.821
NZ_LS483412_1	1.3\|513895\|28\|NZ_LS483412\|CRISPRCasFinder	513895-513922	28	NZ_CP009266	Vibrio coralliilyticus strain OCN014 plasmid pOCN014, complete sequence	77668-77695	6	0.786
NZ_LS483412_1	1.3\|513895\|28\|NZ_LS483412\|CRISPRCasFinder	513895-513922	28	AP013512	Uncultured Mediterranean phage uvMED DNA, complete genome, group G21, isolate: uvMED-CGR-C84-MedDCM-OCT-S29-C65	18412-18439	6	0.786
NZ_LS483412_1	1.5\|514015\|28\|NZ_LS483412\|CRISPRCasFinder	514015-514042	28	CP001772	Spirosoma linguale DSM 74 plasmid pSLIN03, complete sequence	9571-9598	6	0.786
NZ_LS483412_1	1.6\|514075\|28\|NZ_LS483412\|CRISPRCasFinder	514075-514102	28	MG945627	UNVERIFIED: Microviridae sp. isolate 6152-1602, complete genome	4943-4970	6	0.786
NZ_LS483412_1	1.7\|514135\|28\|NZ_LS483412\|CRISPRCasFinder	514135-514162	28	MK016664	Synechococcus phage S-B68, complete genome	82125-82152	6	0.786
NZ_LS483412_1	1.7\|514135\|28\|NZ_LS483412\|CRISPRCasFinder	514135-514162	28	MG945357	UNVERIFIED: Microviridae sp. isolate 2878-18011, complete genome	4023-4050	6	0.786
NZ_LS483412_1	1.7\|514135\|28\|NZ_LS483412\|CRISPRCasFinder	514135-514162	28	MG945367	UNVERIFIED: Microviridae sp. isolate 2878-1801, partial genome	2152-2179	6	0.786
NZ_LS483412_1	1.8\|514195\|28\|NZ_LS483412\|CRISPRCasFinder	514195-514222	28	MN657032	Psychrobacter sp. strain ANT_P15B plasmid pA15BP2, complete sequence	7476-7503	6	0.786
NZ_LS483412_1	1.4\|513955\|28\|NZ_LS483412\|CRISPRCasFinder	513955-513982	28	MK033137	UNVERIFIED: Pseudomonas phage UNO-SLW1, complete genome	19369-19396	7	0.75
NZ_LS483412_1	1.4\|513955\|28\|NZ_LS483412\|CRISPRCasFinder	513955-513982	28	KX449362	Pseudomonas phage UNO-SLW3, complete genome	16334-16361	7	0.75
NZ_LS483412_1	1.4\|513955\|28\|NZ_LS483412\|CRISPRCasFinder	513955-513982	28	KX449363	Pseudomonas phage UNO-SLW4, complete genome	16320-16347	7	0.75
NZ_LS483412_1	1.4\|513955\|28\|NZ_LS483412\|CRISPRCasFinder	513955-513982	28	NC_047873	Pseudomonas phage UNO-SLW1, complete genome	16414-16441	7	0.75
NZ_LS483412_1	1.4\|513955\|28\|NZ_LS483412\|CRISPRCasFinder	513955-513982	28	KX449361	Pseudomonas phage UNO-SLW2, complete genome	16320-16347	7	0.75
NZ_LS483412_1	1.5\|514015\|28\|NZ_LS483412\|CRISPRCasFinder	514015-514042	28	NC_031070	Bacillus phage Nemo, complete genome	129971-129998	7	0.75
NZ_LS483412_1	1.5\|514015\|28\|NZ_LS483412\|CRISPRCasFinder	514015-514042	28	MN038179	Bacillus phage ALPS, complete genome	129126-129153	7	0.75
NZ_LS483412_1	1.5\|514015\|28\|NZ_LS483412\|CRISPRCasFinder	514015-514042	28	MH638311	Bacillus phage OmnioDeoPrimus, complete genome	128883-128910	7	0.75
NZ_LS483412_1	1.5\|514015\|28\|NZ_LS483412\|CRISPRCasFinder	514015-514042	28	MF288918	Bacillus phage Bubs, complete genome	130009-130036	7	0.75
NZ_LS483412_1	1.6\|514075\|28\|NZ_LS483412\|CRISPRCasFinder	514075-514102	28	NC_019401	Cronobacter phage vB_CsaM_GAP32, complete genome	180398-180425	7	0.75
NZ_LS483412_1	1.8\|514195\|28\|NZ_LS483412\|CRISPRCasFinder	514195-514222	28	NZ_CP015329	Bacillus filamentosus strain Hbe603 plasmid pBEH7, complete sequence	1016-1043	7	0.75

1. spacer 1.1|513775|28|NZ_LS483412|CRISPRCasFinder matches to MH617420 (Microviridae sp. isolate ctda655, complete genome) position: , mismatch: 4, identity: 0.857

agctgagttaaaagcggccggttttagt	CRISPR spacer
tgctgacttaaaagcggccggtcttaat	Protospacer
 ***** ***************.***.*

2. spacer 1.2|513835|28|NZ_LS483412|CRISPRCasFinder matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 4, identity: 0.857

aaaggaattgcgtgatgcgggattctcc	CRISPR spacer
acatgaattgcctgctgcgggattctcc	Protospacer
* * ******* ** *************

3. spacer 1.1|513775|28|NZ_LS483412|CRISPRCasFinder matches to KX513870 (Human gut gokushovirus isolate SH-CHD7, complete genome) position: , mismatch: 5, identity: 0.821

agctgagttaaaagcggccggttttagt	CRISPR spacer
cgctgatttaaaagcggcaggtttaaat	Protospacer
 ***** *********** ***** *.*

4. spacer 1.5|514015|28|NZ_LS483412|CRISPRCasFinder matches to MN694311 (Marine virus AFVG_250M573, complete genome) position: , mismatch: 5, identity: 0.821

cgcagagttaaaagcagcaggatttgac	CRISPR spacer
cgcagagtttcaagcagcaggatttata	Protospacer
*********  **************.

5. spacer 1.5|514015|28|NZ_LS483412|CRISPRCasFinder matches to MH572400 (Microviridae sp. isolate SD_SF_26, complete genome) position: , mismatch: 5, identity: 0.821

cgcagagttaaaagcagcaggatttgac	CRISPR spacer
ggcagatttaaaagcagcaggaattaat	Protospacer
 ***** *************** **.*.

6. spacer 1.3|513895|28|NZ_LS483412|CRISPRCasFinder matches to NZ_CP009266 (Vibrio coralliilyticus strain OCN014 plasmid pOCN014, complete sequence) position: , mismatch: 6, identity: 0.786

aaaagatctaaaagacgctggtttttct	CRISPR spacer
ccccgatctaaaagacgcaggttttcct	Protospacer
    ************** ******.**

7. spacer 1.3|513895|28|NZ_LS483412|CRISPRCasFinder matches to AP013512 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G21, isolate: uvMED-CGR-C84-MedDCM-OCT-S29-C65) position: , mismatch: 6, identity: 0.786

aaaagatctaaaagacgctggtttttct	CRISPR spacer
atttaatctaaaagatgctgatttttct	Protospacer
*   .**********.****.*******

8. spacer 1.5|514015|28|NZ_LS483412|CRISPRCasFinder matches to CP001772 (Spirosoma linguale DSM 74 plasmid pSLIN03, complete sequence) position: , mismatch: 6, identity: 0.786

cgcagagttaaaagcagcaggatttgac	CRISPR spacer
aaaagaattaaaagcagtaggatttgat	Protospacer
 . ***.**********.*********.

9. spacer 1.6|514075|28|NZ_LS483412|CRISPRCasFinder matches to MG945627 (UNVERIFIED: Microviridae sp. isolate 6152-1602, complete genome) position: , mismatch: 6, identity: 0.786

tgcagaattaaaagcagccggatttagc	CRISPR spacer
agccgacttaaaagcagccggattaaat	Protospacer
 ** ** ***************** *..

10. spacer 1.7|514135|28|NZ_LS483412|CRISPRCasFinder matches to MK016664 (Synechococcus phage S-B68, complete genome) position: , mismatch: 6, identity: 0.786

ctcggatttgaaaaacgcagggtttagt	CRISPR spacer
agtcgatttgaaaaacgcagcgtttaat	Protospacer
  . **************** *****.*

11. spacer 1.7|514135|28|NZ_LS483412|CRISPRCasFinder matches to MG945357 (UNVERIFIED: Microviridae sp. isolate 2878-18011, complete genome) position: , mismatch: 6, identity: 0.786

ctcggatttgaaaaacgcagggtttagt	CRISPR spacer
acaggatttgaaaaacgcaggtttgaat	Protospacer
 . ****************** ** *.*

12. spacer 1.7|514135|28|NZ_LS483412|CRISPRCasFinder matches to MG945367 (UNVERIFIED: Microviridae sp. isolate 2878-1801, partial genome) position: , mismatch: 6, identity: 0.786

ctcggatttgaaaaacgcagggtttagt	CRISPR spacer
acaggatttgaaaaacgcaggtttgaat	Protospacer
 . ****************** ** *.*

13. spacer 1.8|514195|28|NZ_LS483412|CRISPRCasFinder matches to MN657032 (Psychrobacter sp. strain ANT_P15B plasmid pA15BP2, complete sequence) position: , mismatch: 6, identity: 0.786

cgacgagctaaaaaaagcaggatatacc	CRISPR spacer
tgatcagctaaaaaaagcaggttataaa	Protospacer
.**. **************** ****

14. spacer 1.4|513955|28|NZ_LS483412|CRISPRCasFinder matches to MK033137 (UNVERIFIED: Pseudomonas phage UNO-SLW1, complete genome) position: , mismatch: 7, identity: 0.75

agcacagctcaaggccgctgggttttct	CRISPR spacer
agcgcagctcaaggccgctggcgtccac	Protospacer
***.*****************  *.. .

15. spacer 1.4|513955|28|NZ_LS483412|CRISPRCasFinder matches to KX449362 (Pseudomonas phage UNO-SLW3, complete genome) position: , mismatch: 7, identity: 0.75

agcacagctcaaggccgctgggttttct	CRISPR spacer
agcgcagctcaaggccgctggcgtccac	Protospacer
***.*****************  *.. .

16. spacer 1.4|513955|28|NZ_LS483412|CRISPRCasFinder matches to KX449363 (Pseudomonas phage UNO-SLW4, complete genome) position: , mismatch: 7, identity: 0.75

agcacagctcaaggccgctgggttttct	CRISPR spacer
agcgcagctcaaggccgctggcgtccac	Protospacer
***.*****************  *.. .

17. spacer 1.4|513955|28|NZ_LS483412|CRISPRCasFinder matches to NC_047873 (Pseudomonas phage UNO-SLW1, complete genome) position: , mismatch: 7, identity: 0.75

agcacagctcaaggccgctgggttttct	CRISPR spacer
agcgcagctcaaggccgctggcgtccac	Protospacer
***.*****************  *.. .

18. spacer 1.4|513955|28|NZ_LS483412|CRISPRCasFinder matches to KX449361 (Pseudomonas phage UNO-SLW2, complete genome) position: , mismatch: 7, identity: 0.75

agcacagctcaaggccgctgggttttct	CRISPR spacer
agcgcagctcaaggccgctggcgtccac	Protospacer
***.*****************  *.. .

19. spacer 1.5|514015|28|NZ_LS483412|CRISPRCasFinder matches to NC_031070 (Bacillus phage Nemo, complete genome) position: , mismatch: 7, identity: 0.75

cgcagagttaaaagcagcaggatttgac	CRISPR spacer
gaacaagttaaaggcagcaggatttgaa	Protospacer
 .  .*******.**************

20. spacer 1.5|514015|28|NZ_LS483412|CRISPRCasFinder matches to MN038179 (Bacillus phage ALPS, complete genome) position: , mismatch: 7, identity: 0.75

cgcagagttaaaagcagcaggatttgac	CRISPR spacer
gaacaaattaaaagcagcaggatttgaa	Protospacer
 .  .*.********************

21. spacer 1.5|514015|28|NZ_LS483412|CRISPRCasFinder matches to MH638311 (Bacillus phage OmnioDeoPrimus, complete genome) position: , mismatch: 7, identity: 0.75

cgcagagttaaaagcagcaggatttgac	CRISPR spacer
gaacaagttaaaggcagcaggatttgaa	Protospacer
 .  .*******.**************

22. spacer 1.5|514015|28|NZ_LS483412|CRISPRCasFinder matches to MF288918 (Bacillus phage Bubs, complete genome) position: , mismatch: 7, identity: 0.75

cgcagagttaaaagcagcaggatttgac	CRISPR spacer
gaacaagttaaaggcagcaggatttgaa	Protospacer
 .  .*******.**************

23. spacer 1.6|514075|28|NZ_LS483412|CRISPRCasFinder matches to NC_019401 (Cronobacter phage vB_CsaM_GAP32, complete genome) position: , mismatch: 7, identity: 0.75

tgcagaattaaaagcagccggatttagc	CRISPR spacer
aagagaattacaagcagccggaattact	Protospacer
 . ******* *********** *** .

24. spacer 1.8|514195|28|NZ_LS483412|CRISPRCasFinder matches to NZ_CP015329 (Bacillus filamentosus strain Hbe603 plasmid pBEH7, complete sequence) position: , mismatch: 7, identity: 0.75

cgacgagctaaaaaaagcaggatatacc	CRISPR spacer
aatagaactagaaaaagcaggatatact	Protospacer
 .  **.***.****************.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

965498 : 972381

Acinetobacter_phage(42.86%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_027221196.1\|965498_966275_-	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	1.3e-58	48.6
WP_027221197.1\|966267_967302_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	2.5e-73	47.0
WP_027221198.1\|967279_967858_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	3.5e-56	53.7
WP_027221199.1\|967890_968616_-	LPS export ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.1e-18	25.1
WP_027221200.1\|968612_969122_-	lipopolysaccharide transport periplasmic protein LptA	NA	NA	NA	NA
WP_027221201.1\|969102_969672_-	LPS export ABC transporter periplasmic protein LptC	NA	NA	NA	NA
WP_027221202.1\|969668_970196_-	3-deoxy-manno-octulosonate-8-phosphatase KdsC	A0A140XBD6	Dickeya_phage	2.4e-27	47.7
WP_027221203.1\|970211_971174_-	KpsF/GutQ family sugar-phosphate isomerase	A0A2P0VNK5	Tetraselmis_virus	2.5e-38	32.7
WP_027221204.1\|971583_972381_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.0e-21	33.8

DBSCAN-SWA_2

1229434 : 1279986

Salmonella_phage(20.0%)

integrase,transposase

attL 1226361:1226376|attR 1245238:1245253

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1226361:1226376	attL	NA	NA	NA	NA
WP_010946805.1\|1229434_1230616_-\|integrase	site-specific integrase	A0A0M4QX09	Salmonella_phage	3.5e-42	30.0
WP_027221310.1\|1230906_1231989_-	DUF4917 family protein	NA	NA	NA	NA
WP_027221311.1\|1232326_1233400_+\|integrase	site-specific integrase	A0A0M4R586	Salmonella_phage	1.5e-23	31.0
WP_126299545.1\|1233441_1234215_+	hypothetical protein	NA	NA	NA	NA
WP_027221313.1\|1234359_1234569_+	hypothetical protein	NA	NA	NA	NA
WP_027221314.1\|1234565_1234967_+	hypothetical protein	NA	NA	NA	NA
WP_027221315.1\|1234959_1237491_+	DUF3987 domain-containing protein	A0A2H4JF22	uncultured_Caudovirales_phage	1.1e-05	37.5
WP_050598281.1\|1237697_1238090_+	hypothetical protein	NA	NA	NA	NA
WP_027221316.1\|1238086_1238368_+	hypothetical protein	NA	NA	NA	NA
WP_027221317.1\|1238567_1239263_+	hypothetical protein	NA	NA	NA	NA
WP_080272886.1\|1239829_1240339_-\|transposase	IS630 family transposase	A0A2H4UV16	Bodo_saltans_virus	8.8e-19	28.3
WP_027221318.1\|1240347_1240692_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_080272887.1\|1240839_1240995_+	hypothetical protein	NA	NA	NA	NA
WP_027221319.1\|1241007_1242003_-	virulence protein RhuM/Fic/DOC family protein	Q9JMN3	Wolbachia_phage	4.8e-21	38.9
WP_027221320.1\|1242702_1243023_+	HigA family addiction module antidote protein	M9MUN2	Rhodococcus_phage	1.5e-16	52.3
WP_027221321.1\|1243390_1243777_+	hypothetical protein	NA	NA	NA	NA
WP_027221322.1\|1244003_1245113_+	Fic family protein	NA	NA	NA	NA
WP_027221323.1\|1245244_1245616_+	hypothetical protein	NA	NA	NA	NA
1245238:1245253	attR	NA	NA	NA	NA
WP_027221324.1\|1245612_1245972_+	transcriptional regulator	NA	NA	NA	NA
WP_050598262.1\|1246376_1246694_-	type II toxin-antitoxin system MqsA family antitoxin	NA	NA	NA	NA
WP_027221326.1\|1247058_1247562_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_027221327.1\|1247564_1248746_-	acetylornithine deacetylase	NA	NA	NA	NA
WP_050598263.1\|1248920_1249211_+	hypothetical protein	NA	NA	NA	NA
WP_011214444.1\|1249643_1249811_+	DUF3309 domain-containing protein	NA	NA	NA	NA
WP_158511023.1\|1250242_1251238_+	fatty acid desaturase	NA	NA	NA	NA
WP_027221328.1\|1251360_1251612_-	hypothetical protein	NA	NA	NA	NA
WP_027221329.1\|1251632_1251839_-	CsbD family protein	NA	NA	NA	NA
WP_027221330.1\|1251967_1252321_-	PRC-barrel domain-containing protein	NA	NA	NA	NA
WP_027221331.1\|1252566_1252767_-\|transposase	transposase	A0A1B0Z042	Pseudomonas_phage	9.7e-06	45.8
WP_162492805.1\|1253059_1253140_-\|transposase	transposase	NA	NA	NA	NA
WP_172457046.1\|1253226_1253682_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_027221333.1\|1254372_1255041_+	HAD family phosphatase	A0A1D8KNV9	Synechococcus_phage	1.8e-08	27.4
WP_027221335.1\|1255522_1256356_-	EamA family transporter	NA	NA	NA	NA
WP_027221336.1\|1256779_1256986_+	hypothetical protein	NA	NA	NA	NA
WP_027221337.1\|1257111_1257570_+	hypothetical protein	NA	NA	NA	NA
WP_027221338.1\|1257692_1258295_+	exopolysaccharide biosynthesis protein	NA	NA	NA	NA
WP_032828811.1\|1258397_1259384_-	hypothetical protein	NA	NA	NA	NA
WP_027221340.1\|1259593_1260805_+	hypothetical protein	NA	NA	NA	NA
WP_027221341.1\|1260856_1261843_-	phosphotransferase	NA	NA	NA	NA
WP_027221342.1\|1262053_1262557_+	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_027221343.1\|1262654_1263917_-	hypothetical protein	NA	NA	NA	NA
WP_027221344.1\|1264338_1264758_-	EamA family transporter	NA	NA	NA	NA
WP_027221345.1\|1264958_1265828_-	lipase	NA	NA	NA	NA
WP_027221346.1\|1266069_1268094_-	hypothetical protein	NA	NA	NA	NA
WP_027221347.1\|1268313_1268448_-	hypothetical protein	NA	NA	NA	NA
WP_027221348.1\|1268579_1269275_+	hypothetical protein	NA	NA	NA	NA
WP_027221349.1\|1269348_1269990_-	hypothetical protein	NA	NA	NA	NA
WP_027221350.1\|1270271_1270655_-	hypothetical protein	NA	NA	NA	NA
WP_027221351.1\|1270909_1271611_-	hypothetical protein	NA	NA	NA	NA
WP_027221352.1\|1271970_1274355_-	EAL domain-containing protein	NA	NA	NA	NA
WP_027221353.1\|1274363_1274636_-	KaiB-like protein 2	NA	NA	NA	NA
WP_027221354.1\|1274640_1276293_-	circadian clock protein KaiC	NA	NA	NA	NA
WP_027221355.1\|1276652_1279001_+	chitinase	A0A2K9L6L9	Tupanvirus	9.4e-116	55.3
WP_027221356.1\|1279236_1279986_+\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	6.2e-13	36.4

DBSCAN-SWA_3

1355455 : 1364863

Staphylococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_027221416.1\|1355455_1356784_+	sigma-54-dependent Fis family transcriptional regulator	W8CYM9	Bacillus_phage	2.2e-08	32.0
WP_011213531.1\|1357047_1357293_+	hypothetical protein	NA	NA	NA	NA
WP_027221417.1\|1357424_1358861_-	M48 family metallopeptidase	NA	NA	NA	NA
WP_027221418.1\|1358923_1359997_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	9.5e-31	26.9
WP_027221419.1\|1359981_1360596_+	riboflavin synthase	A0A2I2L4R9	Orpheovirus	1.7e-21	38.4
WP_027221420.1\|1360592_1361804_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.1e-96	47.8
WP_050598266.1\|1361811_1362279_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	2.7e-22	51.4
WP_027221422.1\|1362404_1364042_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	3.6e-154	52.5
WP_027221423.1\|1364038_1364863_+	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	6.8e-53	43.5

DBSCAN-SWA_4

2283874 : 2293992

Bacillus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_027222195.1\|2283874_2285557_-	S8 family serine peptidase	A0A1B0T6A2	Bacillus_phage	4.6e-16	30.9
WP_027222196.1\|2285690_2286698_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_027222197.1\|2286823_2288149_-	adenosylhomocysteinase	S4VPF6	Pandoravirus	1.1e-47	31.2
WP_027222198.1\|2288167_2289316_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.7e-126	58.2
WP_027222199.1\|2289518_2290631_-	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	2.1e-49	34.4
WP_027222200.1\|2290729_2291869_-	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	2.7e-23	26.7
WP_027222201.1\|2292057_2293992_-	molecular chaperone DnaK	G8DDB7	Micromonas_pusilla_virus	1.3e-147	49.6

DBSCAN-SWA_5

2646019 : 2657445

Vibrio_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_027222452.1\|2646019_2647021_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	3.4e-91	50.1
WP_027222453.1\|2647225_2647465_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_027222454.1\|2647666_2648110_+	GatB/YqeY domain-containing protein	A0A292GL36	Xanthomonas_phage	1.4e-20	43.2
WP_027222455.1\|2648118_2649852_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	7.8e-59	35.5
WP_027222456.1\|2649938_2651804_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.3e-35	32.8
WP_027222457.1\|2652057_2652417_+	DUF2513 domain-containing protein	NA	NA	NA	NA
WP_027222459.1\|2652666_2652888_-	hypothetical protein	NA	NA	NA	NA
WP_027222460.1\|2652902_2653394_-	hypothetical protein	NA	NA	NA	NA
WP_032828924.1\|2653403_2654240_-	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A1S6L1V5	Vibrio_phage	2.5e-63	48.9
WP_027222462.1\|2654793_2657445_-	Ti-type conjugative transfer relaxase TraA	A0A1M7XU06	Cedratvirus	2.4e-14	23.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage