CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483411	Haemophilus influenzae strain NCTC11426 chromosome 1	3 crisprs	DEDDh,DinG,cas3,cas14j,RT	0	1	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483411_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483411_1

7641-7790

Orphan

Consensus_repeat	Method
ACTTCTACTGACAAAACAACAGTAGCTGATAATTCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483411_1

>merge|NZ_LS483411|1|7641-7790|CRISPRCasFinder
ACTTCTACTGAAGAAACAACAGTAACTTCTACTGACAAAACAACAGTAGCTGATAATTCAAAAAGCAGTAAGCCAAATCGTAGACATAGAAGAAGTGTTAGCCAGCCTCAAGAGACTTCTACTGAAAAAACAACAGTAGCTGATAATTCA

>NZ_LS483411|1|1|7641-7790|CRISPRCasFinder
ACTTCTACTGAAGAAACAACAGTAACTTCTACTGAC	AAAACAACAGTAGCTGATAATTCAAAAAGCAGTAAGCCAAATCGTAGACATAGAAGAAGTGTTAGCCAGCCTCAAGAG
ACTTCTACTGAAAAAACAACAGTAGCTGATAATTCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483411.1\|WP_111695196.1\|12253_13801_-\|2-isopropylmalate-synthase	unknown	unknown	gnl\|CDD\|234864
NZ_LS483411.1\|WP_005655970.1\|1377_2478_+\|DNA-polymerase-III-subunit-beta	unknown	unknown	gnl\|CDD\|235541
NZ_LS483411.1\|WP_111695197.1\|16287_16869_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483411.1\|WP_011272333.1\|9505_10915_-\|3-isopropylmalate-dehydratase-large-subunit	unknown	unknown	gnl\|CDD\|235490
NZ_LS483411.1\|WP_012055334.1\|14344_15466_+\|DNA-protecting-protein-DprA	unknown	unknown	gnl\|CDD\|223829
NZ_LS483411.1\|WP_005647965.1\|18169_18655_+\|SsrA-binding-protein-SmpB	unknown	unknown	gnl\|CDD\|235455
NZ_LS483411.1\|WP_005655969.1\|2479_3559_+\|DNA-replication/repair-protein-RecF	unknown	unknown	gnl\|CDD\|273173
NZ_LS483411.1\|WP_021034810.1\|0_1365_+\|chromosomal-replication-initiator-protein-DnaA	unknown	unknown	gnl\|CDD\|273037
NZ_LS483411.1\|WP_048955057.1\|16964_17930_+\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
NZ_LS483411.1\|WP_005651583.1\|18749_19049_-\|DNA-binding-transcriptional-regulator-Fis	unknown	unknown	gnl\|CDD\|179020
NZ_LS483411.1\|WP_005666012.1\|15518_16295_+\|peroxide-stress-protein-YaaA	unknown	unknown	gnl\|CDD\|234999
NZ_LS483411.1\|WP_038440278.1\|8878_9481_-\|3-isopropylmalate-dehydratase-small-subunit	unknown	unknown	gnl\|CDD\|179314
NZ_LS483411.1\|WP_038440279.1\|11091_12168_-\|3-isopropylmalate-dehydrogenase	unknown	unknown	gnl\|CDD\|234832

Protein	Function_ID	Function_description	E-value
NZ_LS483411.1\|WP_111695196.1\|12253_13801_-\|2-isopropylmalate-synthase	gnl\|CDD\|234864	PRK00915, PRK00915, 2-isopropylmalate synthase; Validated.	0
NZ_LS483411.1\|WP_005655970.1\|1377_2478_+\|DNA-polymerase-III-subunit-beta	gnl\|CDD\|235541	PRK05643, PRK05643, DNA polymerase III subunit beta; Validated.	6.82627e-180
NZ_LS483411.1\|WP_011272333.1\|9505_10915_-\|3-isopropylmalate-dehydratase-large-subunit	gnl\|CDD\|235490	PRK05478, PRK05478, 3-isopropylmalate dehydratase large subunit.	0
NZ_LS483411.1\|WP_012055334.1\|14344_15466_+\|DNA-protecting-protein-DprA	gnl\|CDD\|223829	COG0758, Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion].	5.07778e-139
NZ_LS483411.1\|WP_005647965.1\|18169_18655_+\|SsrA-binding-protein-SmpB	gnl\|CDD\|235455	PRK05422, smpB, SsrA-binding protein SmpB.	4.52083e-87
NZ_LS483411.1\|WP_005655969.1\|2479_3559_+\|DNA-replication/repair-protein-RecF	gnl\|CDD\|273173	TIGR00611, DNA_replication_and_repair_protein_RecF, recF protein. All proteins in this family for which functions are known are DNA binding proteins that assist the filamentation of RecA onto DNA for the initiation of recombination or recombinational repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair].	1.97894e-178
NZ_LS483411.1\|WP_021034810.1\|0_1365_+\|chromosomal-replication-initiator-protein-DnaA	gnl\|CDD\|273037	TIGR00362, DnaA, chromosomal replication initiator protein DnaA. DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_LS483411.1\|WP_048955057.1\|16964_17930_+\|6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0
NZ_LS483411.1\|WP_005651583.1\|18749_19049_-\|DNA-binding-transcriptional-regulator-Fis	gnl\|CDD\|179020	PRK00430, fis, DNA-binding transcriptional regulator Fis.	5.47901e-55
NZ_LS483411.1\|WP_005666012.1\|15518_16295_+\|peroxide-stress-protein-YaaA	gnl\|CDD\|234999	PRK02101, PRK02101, peroxide stress protein YaaA.	4.39598e-149
NZ_LS483411.1\|WP_038440278.1\|8878_9481_-\|3-isopropylmalate-dehydratase-small-subunit	gnl\|CDD\|179314	PRK01641, leuD, 3-isopropylmalate dehydratase small subunit.	4.01041e-141
NZ_LS483411.1\|WP_038440279.1\|11091_12168_-\|3-isopropylmalate-dehydrogenase	gnl\|CDD\|234832	PRK00772, PRK00772, 3-isopropylmalate dehydrogenase; Provisional.	0

>NZ_LS483411.1|WP_005655969.1|2479_3559_+|DNA-replication/repair-protein-RecF
MAISRLLVEKFRNLTAVDLDFDPCFNFLIGNNGSGKTSLLEAIFYLGHGRSFKSAVTNRIISYDEPHFTLFGQIQESQHQWSVGLQKLRQGNTLVKINGEDGNKISDLAHLLPMQLITPEGLTLLNGGPSYRRAFLDWGLFHHQTSFYSAWSNLNRLLKQRNAALAQNQPYSAIKIWDVELAKLAHQVSQWRAEYAEALRPEIEQTCQLFLPELEINVSFHQGWEKNADYYEILQQNFERDRALNYTFSGPQKADFRFKAQGLPVEDVLSRGQLKLLMCVLRLAQGEHLMKEKQRHCIFLIDDFASELDQYKRALLAERLQQSGSQVFVTAITQRQLKEMQVENKKMFSVHNGIINALN
>NZ_LS483411.1|WP_005655970.1|1377_2478_+|DNA-polymerase-III-subunit-beta
MQFSISRENLLKPLQQVCGVLSNRPNIPVLNNVLLQIEDNRLTITGTDLEVELSSQTQLSSSSENGTFTIPAKKFLDICRTLSDDSEITVTFEQDRALVQSGRSRFTLTTQPAEEYPNLTDWQSEVDFQLPQNTLRRLIEATQFSMANQDARYFLNGMKFETEGNLLRTVATDGHRLAVCTISLEQELQNHSVILPRKGVLELVRLLETNDEPARLQIGTNNLRVHLKNTVFTSKLIDGRFPDYRRVLPRNATKIVEGNWEMLKQAFVRASILSNERARSVRLSLKENQLKITASNTEHEEAEEIVDVNYNGEELEVGFNVTYILDVLNALKCNQVRMRLTDAFSSCLIENCEDSSCEYVIMPMRL
>NZ_LS483411.1|WP_021034810.1|0_1365_+|chromosomal-replication-initiator-protein-DnaA
MTLSNLWQSCLLQLQDQVSASDLSTWLRPLQADAVSNNHIVLYASNMFVKGWVETHYLAQIQQICQTLAQNPELRISLKEGVKPAPKIVESTPNTTLRSESAVDFQTESNTPIKFESHLNTKHLFDNFVEGKSNQLARAVGQKLAQAPGEPSANPFFLYGGTGLGKTHLLHAIGNGILANKPNARVLYIHANNFMQHMVKAVRDNKMDQFKKFYRSLDALLVDDIQFFAEKEKTQEEFFHIFNNLFETGRQIILTSDRYPKEIEKIEERLKSRFGWGLTTAIEPPDLETRVAILLKKAEEHNMNLPEEVAFFIAQRLRTNVRELEGALNRVKAMQDFKGGDIDIDFVRDTLKDILALQERLVTIENIQKVVAEYYRIKVSDLKSKSRARSVTRPRQIAMALAKELTNRSLPEIGRAFDRDHTTVLNACREVPKFREQDNSIQEDWANLIRTLSA
>NZ_LS483411.1|WP_038440278.1|8878_9481_-|3-isopropylmalate-dehydratase-small-subunit
MAGFKQLSGLVVPLDAANVDTDAIIPKQFLQAITRVGFGKHLFHEWRYLDVDGTKPNPEFVLNYPRYQGATILLARKNLGCGSSREHAPWALADYGFKVMIAPSFADIFYNNSLNNHMLPIRLSEEEVEEIFQWVWANDGKQIHVDLEAMTVTVGDKVYHFELDEFRRHCLLNGLDNIGLTLQHEDKISAYEKNIPAFLR
>NZ_LS483411.1|WP_011272333.1|9505_10915_-|3-isopropylmalate-dehydratase-large-subunit
MAKTLYEKLFDSHIVYEAEGETPILYINRHLIHEVTSPQAFDGLRVANRQVRQVNKTFGTMDHSISTQVRDVNKLEGQAKIQVLELDKNTKATGIKLFDITTKEQGIVHVMGPEQGLTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQARAKSMKIEVRGKVASGITAKDIILAIIGKTTMAGGTGHVVEFCGEAIRDLSMEGRMTVCNMAIEMGAKAGLIAPDETTFAYLKDRPHAPKGKDWDDAVAYWKTLKSDDDAQFDTVVTLEAKDIAPQVTWGTNPGQVISVNETIPNPQEMADPVQRASAEKALHYIGLEAGTNLKDIKVDQVFIGSCTNSRIEDLRAAAAVMKGRKKADNVKRILVVPGSGLVKEQAEKEGLDKIFIAAGAEWRNPGCSMCLGMNDDRLGEWERCASTSNRNFEGRQGRNGRTHLVSPAMAAAAGMFGKFVDIREVALN
>NZ_LS483411.1|WP_038440279.1|11091_12168_-|3-isopropylmalate-dehydrogenase
MQSYNIAVLAGDGIGPEVMAEAIKVLNKVQEKFGFKLNFNEFFVGGAAIDHCGYPLPAETLKGCDEADAILFGSVGGPKWTNLPPDQQPERGALLPLRKYFKLFCNLRPATLYKGLEKFCPLRADIAAKGFDMVVVRELTGGIYFGQPKGREGDGTQTKAFDTEVYYKYEIERIARAAFDAAMKRNKKVTSVDKANVLQSSILWRETVTEMAKDYPEVTLEHIYIDNATMQLIKAPESFDVLLCSNIFGDIISDEAAMITGSMGMLPSASLNEEGFGLYEPAGGSAPDIAGKGIANPIAQILSAAMMLRYSFNLNEAADAIESAVQKVLASGHRTADLADDSTPVSTAEMGTLITQAI
>NZ_LS483411.1|WP_111695196.1|12253_13801_-|2-isopropylmalate-synthase
MTDRVIIFDTTLRDGEQALKASLTVKEKLQIALALERLGVDVMEVGFPVSSQGDFESVQTIARHIKNARVAALSRAVDKDIDAAYQALKVAEAFRIHTFIASSALHVEAKLKRSFDDVVGMAVAAVKRARNYTDDVEFSCEDAGRTGIDNICRIVEVAINAGATTVNIPDTVGFCLPNEYGNIIAQVHNRVPNIDKAVISVHCHNDLGMATANSLTAVQNGARQIECTINGIGERAGNTSLEEVVMAMKVRQDFMGVDTRINTQEIHRVSQMVSQLCNMPIQPNKAIVGSNAFAHSSGIHQDGMLKNKNTYEIMSPETIGLKKEKLNLTARSGRAAVKGHMADMGYNEQDYDLDKLYDAFLKLADKKGQVFDYDLEALAFIDMQQGDEDRLVLDKLSAHSTKEYPATAFVQLKLDGEKLSTSSIGGNGPVDAVYNAILNLTGLEIKMSHYNLTAKGEGAEALGQVDIVVEHKGRKFHGVGLATDIVESSALALVHAINAIYRAHKVADIKNHKQH
>NZ_LS483411.1|WP_012055334.1|14344_15466_+|DNA-protecting-protein-DprA
MNDITYTLLRLMQVPKLGGVGIDKILSNITLNELLNYDDVAFRQMGWGAIQIRRWFKPEAKFIEPALAWSQKEGNHLVNYFSPFYPFLLKQTANFPPLLFVKGNLTALSQRQMAMVGSRYCTTYGEYWAKHFATELSLAGFTITSGLALGIDGHCHQAVVNIQGQTIAVLGSGLEQIYPSKHQRLSAQIIENNGALVSEFLPNQAPIAANFPRRNRIISGLSVGTLVVEATEKSGSLITARYALEQNREVFAVPGNIQNESSQGCHRLIKQGAMLVENAKDILETLYQHSIHSQTEIDFDQIAVPNYTPPPDPRRLVEAPSHPKLYSRIGYTPVSIDDLAEEFNLSVDVLLVQLLDLELQDLIISENGLYKRV
>NZ_LS483411.1|WP_005666012.1|15518_16295_+|peroxide-stress-protein-YaaA
MLAIISPAKTLDFESAVKNFPVSQPHFTDYSEQLIEVCRKLSPQDLSSLMSISDKLAGLNAARFAEWTKIHNEDNSRPALFAFKGDVYTGLDADSLSEDDVIFAQSHLRMLSGLYGLLKPLDLMQPYRLEMGTKLANPKGKDLYAFWGNVITQAVQQAIDAQGDNVLVNLASDEYYKSVKENQLNAKIIKPVFLDNKNGKYKVISFYAKKARGLMCRYLIQHRLTDIEQLKEFDLGGYWFDSASSTETEFVFKRDINE
>NZ_LS483411.1|WP_111695197.1|16287_16869_+|hypothetical-protein
MNKIFVILTALILSGCATKLTQLNVPTQLEHNGKNYALTGSQDLETIARYAYISKPDTLENWQSEIEILFDRNQPVRSIKERIALRERIYRNTGVKDFHFDAIPENSTNPNELNGYVIYSPTKENPSWQVNVMKGRQLPQCGFVQYQYSQKVQQPTLSKHLSVDKVQQHLQKYIVDIERKHLQNLKWLLFCEK
>NZ_LS483411.1|WP_048955057.1|16964_17930_+|6-phosphofructokinase
MIKKIAVLTSGGDAPGMNAAIRGVVRSALAEGLEVFGIYDGYQGLYNNKIKQLNRYSVSDVINRGGTFLGSARFPEFKDPNVRAKCAEILRSHGIDALVVIGGDGSYMGAKLLTEEHCFPCVGLPGTIDNDVAGTDYTIGYQTALQTAVDAIDRLRDTSSSHQRISIVEIMGRHCSDLTISAGIAGGCEYIVASEIEFNREELIQQIERSIIRGKRHAIIAITELLTDVHSLAKEIEARVGHETRATVLGHIQRGGSPCAFDRILASRMGAYAVDLLLQGKGGYCVGIQNEQLVHHDIIDAINNMQRVFKADWLKVAKRLE
>NZ_LS483411.1|WP_005647965.1|18169_18655_+|SsrA-binding-protein-SmpB
MTKKKVKPNSNTIALNKRARHDYFIEDEIEAGLELQGWEVKSMRAGKANISDSYVIFKNGEAFLFGASIQPLNVASTHIVCDPTRTRKLLLNKRELASLFGKANRDGFTIVALSLYWKSAWAKVKIGLAKGKKQQDKRDDIKEREWKVTKDRIMKNAHRRS
>NZ_LS483411.1|WP_005651583.1|18749_19049_-|DNA-binding-transcriptional-regulator-Fis
MLEQQRNSADALTVSVLNAQSQVTSKPLRDSVKQALRNYLAQLDGQDVNDLYELVLAEVEHPMLDMIMQYTRGNQTRAANMLGINRGTLRKKLKKYGMG

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Crispr_ID: NZ_LS483411_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483411_2

618019-618098

Orphan

Consensus_repeat	Method
AAGTTATCAATGAAGGGGAAATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483411_2

>merge|NZ_LS483411|2|618019-618098|CRISPRCasFinder
AAGTTATCAATGAAGGGGAAATTAAGGCGAAAGATTTCGTGGTACTTAATGGCGATGAAGTTATCAATGAAGGGAAAATT

>NZ_LS483411|2|2|618019-618098|CRISPRCasFinder
AAGTTATCAATGAAGGGGAAATT	AAGGCGAAAGATTTCGTGGTACTTAATGGCGATG
AAGTTATCAATGAAGGGAAAATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483411.1\|WP_111695382.1\|623139_624165_+\|UDP-N-acetylmuramate-dehydrogenase	unknown	unknown	gnl\|CDD\|234593
NZ_LS483411.1\|WP_111695380.1\|620786_621386_+\|glycerol-3-phosphate-1-O-acyltransferase-PlsY	unknown	unknown	gnl\|CDD\|234691
NZ_LS483411.1\|WP_111688874.1\|624188_624500_+\|DUF2322-family-protein	unknown	unknown	gnl\|CDD\|370810
NZ_LS483411.1\|WP_111695373.1\|609736_610633_-\|glycosyltransferase-family-8-protein	unknown	unknown	gnl\|CDD\|133037
NZ_LS483411.1\|WP_111695381.1\|621426_623130_+\|nitrate/nitrite-two-component-system-sensor-histidine-kinase-NarQ	unknown	unknown	gnl\|CDD\|236800
NZ_LS483411.1\|WP_172453970.1\|615801_617490_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NZ_LS483411.1\|WP_005686687.1\|620347_620704_-\|dihydroneopterin-aldolase	unknown	unknown	gnl\|CDD\|183219
NZ_LS483411.1\|WP_111695376.1\|612170_613214_+\|ADP-heptose--LPS-heptosyltransferase-I	unknown	unknown	gnl\|CDD\|366450
NZ_LS483411.1\|WP_005648863.1\|609002_609326_+\|ribosome-associated-translation-inhibitor-RaiA	unknown	unknown	gnl\|CDD\|182378
NZ_LS483411.1\|WP_005653400.1\|606606_607074_-\|thioredoxin-dependent-thiol-peroxidase	unknown	unknown	gnl\|CDD\|181857
NZ_LS483411.1\|WP_111695372.1\|607174_608071_+\|4-hydroxy-tetrahydrodipicolinate-synthase	unknown	unknown	gnl\|CDD\|235107
NZ_LS483411.1\|WP_111695375.1\|611368_612094_-\|3-deoxy-D-manno-octulosonic-acid-kinase	unknown	unknown	gnl\|CDD\|234975
NZ_LS483411.1\|WP_005686697.1\|627399_628041_-\|orotate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234771
NZ_LS483411.1\|WP_111695374.1\|610769_611357_-\|RdgB/HAM1-family-non-canonical-purine-NTP-pyrophosphatase	unknown	unknown	gnl\|CDD\|234648
NZ_LS483411.1\|WP_111695377.1\|613548_615720_+\|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor	unknown	unknown	gnl\|CDD\|273807
NZ_LS483411.1\|WP_111695385.1\|626454_627321_-\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
NZ_LS483411.1\|WP_111695386.1\|628064_628781_-\|ribonuclease-PH	unknown	unknown	gnl\|CDD\|178914
NZ_LS483411.1\|WP_111695383.1\|624637_625483_+\|RNA-polymerase-sigma-factor-RpoH	unknown	unknown	gnl\|CDD\|235838
NZ_LS483411.1\|WP_111695384.1\|625522_626455_-\|tRNA-dihydrouridine(16)-synthase-DusC	unknown	unknown	gnl\|CDD\|236713
NZ_LS483411.1\|WP_050948883.1\|608182_608830_+\|outer-membrane-protein-assembly-factor-BamC	unknown	unknown	gnl\|CDD\|225854

Protein	Function_ID	Function_description	E-value
NZ_LS483411.1\|WP_111695382.1\|623139_624165_+\|UDP-N-acetylmuramate-dehydrogenase	gnl\|CDD\|234593	PRK00046, murB, UDP-N-acetylmuramate dehydrogenase.	0
NZ_LS483411.1\|WP_111695380.1\|620786_621386_+\|glycerol-3-phosphate-1-O-acyltransferase-PlsY	gnl\|CDD\|234691	PRK00220, PRK00220, glycerol-3-phosphate 1-O-acyltransferase PlsY.	1.89442e-101
NZ_LS483411.1\|WP_111688874.1\|624188_624500_+\|DUF2322-family-protein	gnl\|CDD\|370810	pfam10084, DUF2322, Uncharacterized protein conserved in bacteria (DUF2322). Members of this family of hypothetical bacterial proteins have no known function.	5.73764e-49
NZ_LS483411.1\|WP_111695373.1\|609736_610633_-\|glycosyltransferase-family-8-protein	gnl\|CDD\|133037	cd04194, GT8_A4GalT_like, A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS.	3.82671e-84
NZ_LS483411.1\|WP_111695381.1\|621426_623130_+\|nitrate/nitrite-two-component-system-sensor-histidine-kinase-NarQ	gnl\|CDD\|236800	PRK10935, PRK10935, nitrate/nitrite two-component system sensor histidine kinase NarQ.	0
NZ_LS483411.1\|WP_172453970.1\|615801_617490_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	2.5894e-123
NZ_LS483411.1\|WP_005686687.1\|620347_620704_-\|dihydroneopterin-aldolase	gnl\|CDD\|183219	PRK11593, folB, bifunctional dihydroneopterin aldolase/7,8-dihydroneopterin epimerase.	1.25571e-52
NZ_LS483411.1\|WP_111695376.1\|612170_613214_+\|ADP-heptose--LPS-heptosyltransferase-I	gnl\|CDD\|366450	pfam01075, Glyco_transf_9, Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core.	1.0711e-98
NZ_LS483411.1\|WP_005648863.1\|609002_609326_+\|ribosome-associated-translation-inhibitor-RaiA	gnl\|CDD\|182378	PRK10324, PRK10324, ribosome-associated translation inhibitor RaiA.	6.00428e-42
NZ_LS483411.1\|WP_005653400.1\|606606_607074_-\|thioredoxin-dependent-thiol-peroxidase	gnl\|CDD\|181857	PRK09437, bcp, thioredoxin-dependent thiol peroxidase; Reviewed.	1.04613e-113
NZ_LS483411.1\|WP_111695372.1\|607174_608071_+\|4-hydroxy-tetrahydrodipicolinate-synthase	gnl\|CDD\|235107	PRK03170, PRK03170, dihydrodipicolinate synthase; Provisional.	2.4903e-172
NZ_LS483411.1\|WP_111695375.1\|611368_612094_-\|3-deoxy-D-manno-octulosonic-acid-kinase	gnl\|CDD\|234975	PRK01723, PRK01723, 3-deoxy-D-manno-octulosonic-acid kinase; Reviewed.	5.30573e-129
NZ_LS483411.1\|WP_005686697.1\|627399_628041_-\|orotate-phosphoribosyltransferase	gnl\|CDD\|234771	PRK00455, pyrE, orotate phosphoribosyltransferase; Validated.	3.0683e-88
NZ_LS483411.1\|WP_111695374.1\|610769_611357_-\|RdgB/HAM1-family-non-canonical-purine-NTP-pyrophosphatase	gnl\|CDD\|234648	PRK00120, PRK00120, dITP/XTP pyrophosphatase; Reviewed.	4.04155e-115
NZ_LS483411.1\|WP_111695377.1\|613548_615720_+\|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor	gnl\|CDD\|273807	TIGR01785, Heme/hemopexin_utilization_protein_C, TonB-dependent heme/hemoglobin receptor family protein. This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	0
NZ_LS483411.1\|WP_111695385.1\|626454_627321_-\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	5.3522e-157
NZ_LS483411.1\|WP_111695386.1\|628064_628781_-\|ribonuclease-PH	gnl\|CDD\|178914	PRK00173, rph, ribonuclease PH; Reviewed.	1.83841e-179
NZ_LS483411.1\|WP_111695383.1\|624637_625483_+\|RNA-polymerase-sigma-factor-RpoH	gnl\|CDD\|235838	PRK06596, PRK06596, RNA polymerase factor sigma-32; Reviewed.	0
NZ_LS483411.1\|WP_111695384.1\|625522_626455_-\|tRNA-dihydrouridine(16)-synthase-DusC	gnl\|CDD\|236713	PRK10550, PRK10550, tRNA dihydrouridine(16) synthase DusC.	0
NZ_LS483411.1\|WP_050948883.1\|608182_608830_+\|outer-membrane-protein-assembly-factor-BamC	gnl\|CDD\|225854	COG3317, NlpB, Uncharacterized lipoprotein [Cell envelope biogenesis, outer membrane].	4.56749e-77

>NZ_LS483411.1|WP_172453970.1|615801_617490_+|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MRPRYSVIASAVSLGFVLSNSVMALVPNAGSLNRELEQRQIQPEAKPSGELFNQAAKSPYTAQYKQELKFPLTQVQILDRNNQEVAADELAHILKNYVGKEVSLSDLSNLANEISEFYRHNNYLVAKAILPPQEIEQGTVKILLLKGNVGEIRLQNHSALSNKFVSRLSNTTVNTSEFILKDELEKFALTINDVPGVNAGLQLSAGKKVGEANLLIKINDAKRFSSYVSVDNQGNKYTGRYRLAAGTKVSNLNGWGDELKLDLLSSNQANLKNARIDYSSLIDGYSTRFGVTANYLHYKLGGNFKSLQSQGHSHTLGAYLLHPTIRTPNFRLSTKVSFNHQNLTDKQQAVSVKQKRKINSLTAGIDGSWNLIKDGTTYFSLSTLFGNLANQTSEKQHNAVENFQPQSHFTVYNYRLSHEQILPKSFAFNIGINGQFADKTLESSQKMLLGGLSGVRGHQAGAASVDEGHLIQTEFKHYLPVFSQSVLVSSLFYDYGFGKSYKHSQFLAKGVKNSVKLQSVGAGLSLSDAGSYAINTSIAKPLDNNINNADKHQFWLSMIKTF
>NZ_LS483411.1|WP_111695377.1|613548_615720_+|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor
MRFSKLSLAIATTLVTANALAQSVELDSINVIATRDPSRFAYTPEKQSKDSLLSKQATSVAAALEDIPNVDIRGGSRSIAQKPNIRGLSDNRVVQVIDGVRQNFDLAHRGSYFLPMSLIQEIEVIKGPSSSLWGSGALGGVVAMRTPNALDLLKNNDKLGVKIRQGYQTANNLSERDASVFAANDKFDVLISAFYNNADNLRTGKGNKLNNTAYKQFGGLAKFGWQINDANRVELSHRETRFKQTAPSNNEVENELTNEKIIDQINEFHGPSDSFPPIKRKPSEISEFYSKVKTRFGSVSYLSDQQIPDQSTVFNYYLTPDNPYLNTHIALYNNKTIEKEQRKVSGVKDQTKLTTRGINLRNSSELSHISFVYGVDYMRDKISTERGTNSNDAKFRADPYNANSNTTGVYLIAHIPLFGEKLLVSPSVRYDHYDTSSKTVKYKDNHLSPATKLTWKVTNWLDFSAKYNEAFRAPSMQERFVSGAHFGANTLGLDQVNRFVANPNLRPETAKNKEITANLHFDSLFKQGDKFKIEATYFRNDVKDFINLKIFNDAKTNTNASANPNTNTNRAFLPTKSQYQNITNARLSGIELQAQYQTERLTLFTNYGSTKGRDKDSGEALSNIAASKIGVGADYALVKDKFTVGATITHYAAQHRVPKDHGVTYPSYILTDLRATYAPLKGEWKNLRLDFALENLFDRKYQPAFSLMEGTGRNAKISAVYSF
>NZ_LS483411.1|WP_111695376.1|612170_613214_+|ADP-heptose--LPS-heptosyltransferase-I
MPLFTEAPKSLCILRLSAVGDVCHALAVVQHIQAYYPQTEMTWIVGKTEMGLLSGIPNVSLIPYDKKTGWKGVLSLWKQLKNKQFDALLNMQTAFRASILSLGIKAKFKIGFGEKRSREGQWLFVNRRIRDPFSPHVLDGFMAFAEYIGVPKVEPKWQLAISQDDDKFADQFIDFSRKNLLISPCSSKAEKDWLIERYAEVANIAHQHNVNVIFCSSPAKRELEIVEKITALCHFTPTNIAGKTNLKQLTALISKVDLVLSPDSGPAHIATTQGTPVIGLYAYHNPLRTAPYNNLDNVVSVYEENAQKEFGKPSSELPWATKLKGKNLMAEIQVEPVIEQMKKLGLF
>NZ_LS483411.1|WP_111695375.1|611368_612094_-|3-deoxy-D-manno-octulosonic-acid-kinase
MHQFQQDNQYFIFNFDRTFDQATEFFQAEFWQKQERVIGSAKGRGITYFLQTEDWFGVNCALRHYYRGGLWGKLNKDRYRFSDLETTRSFAEFHLLQRLYEAGLPVPKPIAARIQKGKLGICYQADILTEKIENAQDLTALLQTQTLPKETWRQIGRLIRKLHDLQICHTDLNAHNILLQQAEQGQKCWLLDFDKCGEKSGDFWKVQNLNRLKRSFEKEVGRMNIQFTEQNWADLTSAYHQ
>NZ_LS483411.1|WP_111695374.1|610769_611357_-|RdgB/HAM1-family-non-canonical-purine-NTP-pyrophosphatase
MKQKIVLATGNKGKVKEMADVLSDFGFEVIAQTDLGIESPEETGLTFVENALLKARYASEKSGLPAIADDSGLVVSSLNGAPGLYSARYAGEEGNDAKNREKLLAELAHIAQDQRQAKFVSCIVFLQHPTDPSPIIAEGECHGVIGFEEKGENGFGYDSLFFSPEQGCTFAELETVEKKKISHRAKALSVLKNKL
>NZ_LS483411.1|WP_111695373.1|609736_610633_-|glycosyltransferase-family-8-protein
MNIIFSSDNYYATYLAVSIFSIIKNTPEKINFYILDMKINQENKTIINNLASAYSCKVFFLPVCEADFQNFPKTIDYISLATYARLNLTKYIKNIEKAIYIDVDTLTNSSLQELWDIDITNYYLAACRDTFIDVKNEAYKKSIGLEGYSYFNAGILLINLNKWKEENIFQKSINWMNKYNNVMKYQDQDILNGICKGKVKFINNRFNFTPTDRDLIKKKNLLHVKMPIIISHYCGPYKFWHKKCGHLNCHIGNLLLKEMDKIIDIPSSWYDHFEKIPFLIKIKRLRKRIKDKLIYGIY
>NZ_LS483411.1|WP_005648863.1|609002_609326_+|ribosome-associated-translation-inhibitor-RaiA
MTLNITSKQMDITPAIREHLEERLAKLGKWQTQLISPHFVLNKVPNGFTVEASIGTPLGNLLASATSDDMYKAINEVEEKLERQLNKLQHKSESRRANERLKDSFEN
>NZ_LS483411.1|WP_050948883.1|608182_608830_+|outer-membrane-protein-assembly-factor-BamC
MKKIILSLITAIILAGCSSNPETLKASNDSFQKSEASIPHFSPLATGGVQLPKADDAYSLPNIEVKKRGDIDIRPPLIPLAIIQNSITKFDGERSLIVYPKQEAKLYNLQQVKRLLKEEGISSTTNGSILTTDWTKTERIGDKSIEIKYQIEQVMTPDVSAITVSILHMRRDGIIFTPNVSDKQYYTSERLNRIVLTLTTAYNKQLQDLSSTSIQ
>NZ_LS483411.1|WP_111695372.1|607174_608071_+|4-hydroxy-tetrahydrodipicolinate-synthase
MSAQNSLFSGSIVALVTPMNHYGEVDFSCLEKLVEHHIEAGSNALVSVGTTGESATLSIEENVKVIEKTVEFAKGRIPIIAGAGANATSEAITMTKLLRDSGVAGCLSVVPYYNKPTQEGMYQHFKAIAECTDLPQILYNVPSRTGSDMKPETVARLAEIENIVGIKEATRDVSRIVKIKQLAGKNFIVLSGDDATGLEAIKLGAEGVISVTNNIAAKDMADMCRYALVGDFDKAEEINARLMRLHHDLFIESNPIPVKWAAYRLGLIKSPHLRLPLTTLSEEIQPKVEDALKIAGLL
>NZ_LS483411.1|WP_005653400.1|606606_607074_-|thioredoxin-dependent-thiol-peroxidase
MNPLSVGNQAPAFTLLNQQEKFVSLSDFRGKKVLIYFYPKALTPGCTTQACGLRDSKSELDALGLVVLGISPDAPKKLAQFIEKKELNFTLLSDPDHQVAEQFGVWGEKKFMGRTYDGIHRISFLINESGTIMQVFDKFKIKDHHQMIIDYLRSL
>NZ_LS483411.1|WP_005686687.1|620347_620704_-|dihydroneopterin-aldolase
MDRIFIEELTVFAQIGVYDWEQQIKQKLVFDLEMAWDCKQAAETDDVAYCLNYAEVSQVIIDYVESKPFLLIERVAYEVADLLESRYQLQGLKIKLSKPKAVAQARNVGVLVIRGCLK
>NZ_LS483411.1|WP_111695380.1|620786_621386_+|glycerol-3-phosphate-1-O-acyltransferase-PlsY
MSLFALFYMLFAYLLGSISSAILICRLTGLPDPRQNGSHNPGATNVLRIGNRKSALAVLIFDMLKGMIPVWAGYYLGLTQFELGMVALGACLGHIFPIFFQFKGGKGVATAFGAIAPISWAVAGSMFGTWIFVFLISGYSSLSAVLTALLVPFYVWWFKPEFTFPVALVCCLLIYRHHDNIQRLWRGQEDKVWAKFKKK
>NZ_LS483411.1|WP_111695381.1|621426_623130_+|nitrate/nitrite-two-component-system-sensor-histidine-kinase-NarQ
MHTKRSVSTRIAKYLFIILIVAGVISSLSLAIISSNKYDAKAINISGSLRMQSYRLLYEMRTQPESIENNLRRYQVSLHSSALLETQNQFFTPKAVKLSYQTILRRWAIMEKYARQYDVKNYSEQLTDYVADVDHFVFELQRFSEQKWILGVSVLFFAMLLILAMVSYVIWYTQREVVKPLHLMTKASMQVQMRQFNHIPLDTRKQNELGTLARVFTQMSTELGQLYSRLEEAVNEKTQKLRQTNRTLSTLYQSAQLLNTNTINDKILNQVLNYIFISEHLNFVKVEVMGAEHWDITLGERETDSALQIEPLSVDNEELGVLSWQAGLPCPDPRIMQNLAQMLARALYFHKNLRQKEQLLLMEERSIIARELHDSLAQVLSFLQIQLTLLKHNLKKEDEQSKEKSLAIIADFEQALSGGYAQLRELLATFRLTIQEANLQLALEQVINSLRTQTSMQMNVKSQLPSQSLNPQQLVHILQIVREATTNAIKHSQGTAIEISARINAEGEYEILVEDDGVGIPTLEEPEGHYGLNIMAERCRQLNAQLHIHRREQGGTQVKITLPHTLF
>NZ_LS483411.1|WP_111695382.1|623139_624165_+|UDP-N-acetylmuramate-dehydrogenase
MQNLQPFHTFHIQSNAREIIEAHSIEQLQQVWAHSKSENLPVLFLGQGSNVLFLDDFNGVVVLNRLMGITHEQNAHFHYLHVNGGENWHKLVEWSINNGIYGLENLALIPGCAGSAPIQNIGAYGVEFKDVCDYVDVLNLNTNETFRLDTEQCEFGYRESTFKHRYQQGYVITAVGLKLKKDWQPILKYGSLVAFDPKTVTAKQIFDEVCHIRQSKLPDPNETGNAGSFFKNPVVSSEHFEEIKKHHKNLPHFPQADGSVKLAAGWLIDQCNLKGFQIGGAAVHKKQALVLINKSGATGQDVVKLAHHVRQTVAEKFGVYLQPEVRFISATGEVNSEQTIA
>NZ_LS483411.1|WP_111688874.1|624188_624500_+|DUF2322-family-protein
MNFKEILETLPNIDHLMGLNVMNGETIIHNIPAIQGKLGSLRLYNALAEKFNGKLNRTSAQQGVEWFAEHVEDAKANPGKHPNIDLLFKVVDENLNLTLIPLC
>NZ_LS483411.1|WP_111695383.1|624637_625483_+|RNA-polymerase-sigma-factor-RpoH
MDKETQMMLVPQGSIEGYIRAANEYPMLTAEEEKELAERLYYHEDLDAAKKLILSHLRFVIHVARGYSGYGLPQADLIQEGNIGLMKAVKRFNPEVGVRLVSFAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRLGWFNENEVDMVANELGVSKEDVIEMESRMSGADVGFDLPTDDAETETYSPSLYLEDKSSNFAAELENENFESQATEQLSTALQSLDARSQDIIKARWLDDNKATLHDLAAKYNVSAERIRQLETNALKKLKSAVNF
>NZ_LS483411.1|WP_111695384.1|625522_626455_-|tRNA-dihydrouridine(16)-synthase-DusC
MRVILAPMQGVLDPFVRQLLTEVNDYDLCITEFVRVVDQLLPEKVFYRLCPELKNQGFTSSGTPVRVQLLGQHPECLAENAIRAIELGSHGIDLNCGCPSKTVNGSNGGAALLKQPELIYRATQALRQAVPSEFPVSVKVRLGWDNISQAFEIADAVEQGGATEITVHGRTKSDGYRADRINWKKIGKVREHLSIPVIANGEIWHWQDGQDCLSQTGCQDLMVGRGALNIPNLSHVLKSNTEKMPWREIQKILQKYANVENEYGSGFYHVARIKQWLRYLNKEYDEANKVFDKIKTCQTAEDLKLRLNDK
>NZ_LS483411.1|WP_111695385.1|626454_627321_-|co-chaperone-DjlA
MNFIGKIIGVFLGWKVGGFFGAIAGLILGSIADKKLYELGSVSSSFFKKKTTRQDLFMQTTFAVLGHLSKSKGRVTEEDIQLANQLMIQLKLDDAGRKLAQDAFRRGKESDFPIRQVIREFRIGCGQRTDLLRMFLQVQVQAAFADSELHENEKEVLYVIAEELGLSRMQFEQMIAMEMAARAFTQGGFYQQYQQGAYQGGYQYQQQNSGGYQHASGPTLNDAYKVLGVTESDEQQVVKRAYRRLMNEHHPDKLVAKGLPPEMMEMAKEKTQQIQAAYDLICKAKGWK
>NZ_LS483411.1|WP_005686697.1|627399_628041_-|orotate-phosphoribosyltransferase
MEQYKRDFIEFALSRNVLKFGEFTLKSGRKSPYFFNAGLFNTGADLARLGEFYAAAIQASAVDFDVVFGPAYKGIPIGTSVSVALFNRYGIDKPVCFNRKEVKDHGEGGNLIGSPLQGKILLVDDVITAGTAIRESMELISANQAELAAVLIALNRKERGKGELSAIQEVERDYQCQVLSIIDLDDLMQFIEQDPRYSSHLPEMRAYRAEFGV
>NZ_LS483411.1|WP_111695386.1|628064_628781_-|ribonuclease-PH
MRPNNRENNQLRQIKITRNYTKHAEGSVLVEFGDTKVLCTATVEDAVPRFLKGQGQGWVTAEYGMLPRSTHSRMQREAAKGKQGGRTMEIQRLIARSLRAMVDLKALGERAITLDCDVIQADGGTRTASITGAAIALCDAINGLIENGTLKTNPIKGLVSAISVGIVEGQAVCDLEYVEDSAAETDMNVVMMEDGRMIEVQGTAEGEPFSHEELLTLLDLAKQGCNQIFIAQREALGL

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Crispr_ID: NZ_LS483411_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483411_3

1461034-1461120

Orphan

Consensus_repeat	Method
AAATAATTATCCTTAGTCATATTTATTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483411_3

>merge|NZ_LS483411|3|1461034-1461120|CRISPRCasFinder
AAATAATTATCCTTAGTCATATTTATTTTATCGTGAGCGTAAGCCCACTCATTTAACTCAAATAATTATCCTTGTCATATTTATTTT

>NZ_LS483411|3|3|1461034-1461120|CRISPRCasFinder
AAATAATTATCCTTAGTCATATTTATTTT	ATCGTGAGCGTAAGCCCACTCATTTAACT
CAAATAATTATCCTTGTCATATTTATTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483411.1\|WP_050949271.1\|1455542_1456175_-\|aldolase	unknown	unknown	gnl\|CDD\|181241
NZ_LS483411.1\|WP_050847019.1\|1453760_1454708_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187549
NZ_LS483411.1\|WP_021035098.1\|1449418_1449982_-\|aquaporin-family-protein	unknown	unknown	gnl\|CDD\|223653
NZ_LS483411.1\|WP_111695622.1\|1467465_1468110_-\|type-1-fimbrial-protein	unknown	unknown	gnl\|CDD\|226069
NZ_LS483411.1\|WP_111695617.1\|1462383_1463037_-\|type-1-fimbrial-protein	unknown	unknown	gnl\|CDD\|226069
NZ_LS483411.1\|WP_111695620.1\|1466358_1466646_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483411.1\|WP_111695613.1\|1452285_1453752_-\|GntP-family-permease	unknown	unknown	gnl\|CDD\|308194
NZ_LS483411.1\|WP_111695621.1\|1466679_1467387_-\|fimbria/pilus-periplasmic-chaperone	unknown	unknown	gnl\|CDD\|225663
NZ_LS483411.1\|WP_172453983.1\|1469366_1470095_-\|molybdate-ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|181841
NZ_LS483411.1\|WP_111695618.1\|1463029_1463665_-\|type-1-fimbrial-protein	unknown	unknown	gnl\|CDD\|226069
NZ_LS483411.1\|WP_111695624.1\|1470217_1470982_-\|molybdate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|182641
NZ_LS483411.1\|WP_162690879.1\|1449941_1450130_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483411.1\|WP_111695614.1\|1454763_1455540_-\|hydroxypyruvate-isomerase-family-protein	unknown	unknown	gnl\|CDD\|226149
NZ_LS483411.1\|WP_015702001.1\|1457415_1458321_-\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224995
NZ_LS483411.1\|WP_111695615.1\|1456171_1457413_-\|four-carbon-acid-sugar-kinase-family-protein	unknown	unknown	gnl\|CDD\|225930
NZ_LS483411.1\|WP_111695619.1\|1463665_1466248_-\|fimbrial-biogenesis-outer-membrane-usher-protein	unknown	unknown	gnl\|CDD\|225729
NZ_LS483411.1\|WP_111695612.1\|1450883_1452227_-\|phospholipase	unknown	unknown	gnl\|CDD\|226584
NZ_LS483411.1\|WP_041175318.1\|1458491_1459250_+\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NZ_LS483411.1\|WP_111695623.1\|1468324_1469380_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	unknown	unknown	gnl\|CDD\|182993
NZ_LS483411.1\|WP_111695616.1\|1461152_1462391_-\|fimbrial-protein	unknown	unknown	gnl\|CDD\|366088

Protein	Function_ID	Function_description	E-value
NZ_LS483411.1\|WP_050949271.1\|1455542_1456175_-\|aldolase	gnl\|CDD\|181241	PRK08130, PRK08130, putative aldolase; Validated.	9.08322e-138
NZ_LS483411.1\|WP_050847019.1\|1453760_1454708_-\|SDR-family-oxidoreductase	gnl\|CDD\|187549	cd05238, Gne_like_SDR_e, Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs. Nucleoside-diphosphate-sugar 4-epimerase has the characteristic active site tetrad and NAD-binding motif of the extended SDR, and is related to more specifically defined epimerases such as UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), which catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup includes Escherichia coli 055:H7 Gne, a UDP-GlcNAc 4-epimerase, essential for O55 antigen synthesis. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.45124e-162
NZ_LS483411.1\|WP_021035098.1\|1449418_1449982_-\|aquaporin-family-protein	gnl\|CDD\|223653	COG0580, GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism].	5.77117e-43
NZ_LS483411.1\|WP_111695622.1\|1467465_1468110_-\|type-1-fimbrial-protein	gnl\|CDD\|226069	COG3539, FimA, P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion].	6.75426e-19
NZ_LS483411.1\|WP_111695617.1\|1462383_1463037_-\|type-1-fimbrial-protein	gnl\|CDD\|226069	COG3539, FimA, P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion].	8.54829e-08
NZ_LS483411.1\|WP_111695613.1\|1452285_1453752_-\|GntP-family-permease	gnl\|CDD\|308194	pfam02447, GntP_permease, GntP family permease. This is a family of integral membrane permeases that are involved in gluconate uptake. E. coli contains several members of this family including GntU, a low affinity transporter, and GntT, a high affinity transporter.	5.51824e-164
NZ_LS483411.1\|WP_111695621.1\|1466679_1467387_-\|fimbria/pilus-periplasmic-chaperone	gnl\|CDD\|225663	COG3121, FimC, P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion].	1.29307e-79
NZ_LS483411.1\|WP_172453983.1\|1469366_1470095_-\|molybdate-ABC-transporter-permease-subunit	gnl\|CDD\|181841	PRK09421, modB, molybdate ABC transporter permease subunit.	1.72447e-140
NZ_LS483411.1\|WP_111695618.1\|1463029_1463665_-\|type-1-fimbrial-protein	gnl\|CDD\|226069	COG3539, FimA, P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion].	2.36695e-15
NZ_LS483411.1\|WP_111695624.1\|1470217_1470982_-\|molybdate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|182641	PRK10677, modA, molybdate transporter periplasmic protein; Provisional.	1.17437e-99
NZ_LS483411.1\|WP_111695614.1\|1454763_1455540_-\|hydroxypyruvate-isomerase-family-protein	gnl\|CDD\|226149	COG3622, Hfi, Hydroxypyruvate isomerase [Carbohydrate transport and metabolism].	1.03794e-152
NZ_LS483411.1\|WP_015702001.1\|1457415_1458321_-\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|224995	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism].	5.61656e-96
NZ_LS483411.1\|WP_111695615.1\|1456171_1457413_-\|four-carbon-acid-sugar-kinase-family-protein	gnl\|CDD\|225930	COG3395, COG3395, Uncharacterized protein conserved in bacteria [Function unknown].	0
NZ_LS483411.1\|WP_111695619.1\|1463665_1466248_-\|fimbrial-biogenesis-outer-membrane-usher-protein	gnl\|CDD\|225729	COG3188, FimD, P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion].	0
NZ_LS483411.1\|WP_111695612.1\|1450883_1452227_-\|phospholipase	gnl\|CDD\|226584	COG4099, COG4099, Predicted peptidase [General function prediction only].	3.13401e-105
NZ_LS483411.1\|WP_041175318.1\|1458491_1459250_+\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	6.92802e-96
NZ_LS483411.1\|WP_111695623.1\|1468324_1469380_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	gnl\|CDD\|182993	PRK11144, modC, molybdenum ABC transporter ATP-binding protein ModC.	0
NZ_LS483411.1\|WP_111695616.1\|1461152_1462391_-\|fimbrial-protein	gnl\|CDD\|366088	pfam00419, Fimbrial, Fimbrial protein.	5.85729e-06

>NZ_LS483411.1|WP_041175318.1|1458491_1459250_+|DeoR/GlpR-transcriptional-regulator
MIPAERQKTLLNLISKQGVISINNLVNILGVSHMTVRRDIQKLEEDGKVISVSGGVQLLERLSSEPTHDDKSLLATTEKTAISKKAVELIQEHSTIYLDAGTTTLEIAKQIANRNDLLVITNDFVIAHYLMVNSQCNIMHTGGLINKSNRSSVGEFAAQFLHQISVDIAFISTSSWNLKGLTTPDEQKIPVKKAIIQFSQKNILVTDSSKYGKVATFLLYPLSSLDTIICDKGLPENAQARIAEMNVELFLV
>NZ_LS483411.1|WP_015702001.1|1457415_1458321_-|NAD(P)-dependent-oxidoreductase
MENQNYSVAVIGLGSMGMGAAVSCINAGLTTYGIDLNPVALEKLKAAGAKAVAANGYDFAHELDAVVILVVNAAQANAVLFGENGIAKKLKAGTAVMVSSTMAAQDAQIISQKLTELGLIMLDAPVSGGAAKALKGEMTVMASGSKQAFELLQPVLDATAAKVYNIGEEIGLGATVKIVHQLLAGVHIAAGAEAMALASKAGIPLDVMYDVVTNAAGNSWMFENRMKHVVEGDYTPLSMVDIFVKDLGLVNDTAKSLHFPLHLASTAYSMFTEASNAGYGKEDDSAVIKIFSGVNLPKKGA
>NZ_LS483411.1|WP_111695615.1|1456171_1457413_-|four-carbon-acid-sugar-kinase-family-protein
MLGVIADDFTGASDIASFLVENGLSTVQMNGVPTQSLNSKVNAIVISLKSRSNPVNQAIEQSLRAYQWLKENGCTQFYFKYCSTFDSTAKGNIGPVTDALLDELNEDFTVITPALPVNGRTIFNGYLFVSDLLLSESGMKNHPITPMTDANLMRLMDAQAKGKTGLVAYSDVIKGASRVQERFAELKAQGYRYAVVDAVDNSQLEVLAEAVADFKLVTGGSGLAAYMAARLSGGKKGVNAFTPNKGKTVVLSGSCSVMTNKQVEKYREKAPHFQLDVEQAIHNENYVEQLYQWVIANLDSEFAPIVYATVQPDVLKAIQHQFGVDQASHAIESIFAKLAAKLKQAGVVNFITAGGETSSIVVQELGFTGFHIGKQIAPGVPWLKAVEEDIFLALKSGNFGKEDFFEYAQGMFL
>NZ_LS483411.1|WP_050949271.1|1455542_1456175_-|aldolase
MTDLAQKELMVQLGRSFYERGYTVGGAGNLSVRLDDNRVLVTPTGSSLGRLSVERLSVLDMEGNLLGGDKPSKEAVFHLAMYKKNPECKAIVHLHSTYLTALSCLDNLDPNNAIEPFTPYYVMRVGKMQVIPYYRPGSPKIAEELSNRALTGKAFLLANHGVVVTGSDLLDAADNTEELEETAKLFFILKGQKIRYLTDDEIKDLEHRGK
>NZ_LS483411.1|WP_111695614.1|1454763_1455540_-|hydroxypyruvate-isomerase-family-protein
MPKFAANLTMMFNEVPFLERFEVAANAGFKYVEYLWPYDYPAKELKAKLDQYGLTQVLFNTSAGDVTKGEWGIAATPGREAEARQHIDQALEYAITLNCPTVHIMAAVVPEGANREDYKQTFVENIRYAAEKFKPHGINICLEALSPEVKPNYFLKSQYDTLDIVELVDRDNVFVQLDYFHAQNVDGNLSRLTDKLNGKFAHVQIASVPARHEPDEGEINYQYIFDKLDEIGYTGYVGCEYKPRGETVAGLDWFQKYK
>NZ_LS483411.1|WP_050847019.1|1453760_1454708_-|SDR-family-oxidoreductase
MKVVITGGQGFLGQRLAKTLLAQNDVHIDDLILIDVVKPIAPNNDPRVRCYEMDLRYPTGLDELITEETDAIFHLAAIVSSHAEQDPDLGYEINFLATRNILEICRKNNPKVRFIFSSSLAIFGGELPETILDSTAFTPQSTYGTQKAMCELLINDYSRKGFVDGIVIRLPTICIRPGKPNKAASSFVSSIMREPLHGEDAVCPVSEELRLWLSSPNTVVANFIHALQLPSLPLRSWHTINLPGFSVTVKQMLSDLTQVKGEAILEHIKFEFDESINNIVASWPARIDNTQALALGFKVDSNFQNVIQQFIEYDM
>NZ_LS483411.1|WP_111695613.1|1452285_1453752_-|GntP-family-permease
MFGLPIPIIGLLIAVFVLVFLVLRTRVHAFIAMLIAASIAGLVGGMSADETLNSITKGFGGTLGSIGIVIGLGVMMGSVLEVSGAAEKMAYSFIKMLGQKKEEWALAITGYVVSIPIFVDSAFVILYPVAKALAKNGKRSLLTLGVALAGGLVVTHHTVPPTPGPLGVAGLFGVDIGAMLLTGVCMAVLPVVGIVLYAKWLDKKYPNFNQEVFTEEELKQKYDSYIESREKKELPSLGLSLLPIVLPIILIFIKAVVHLFVKDVPEALTSIPYQIVSFLGHPVIALALSVLISVYTLLPKADKNTTALHLEEGVKTAGIILLVTGAGGALGAVLRDSGAGKQLAEQIANLPISPILIPFIVSTLVRFIQGSGTVAMITAASISAPILAQIPGVNMLLAAQAATMGSLFFGYFNDSLFWVVNRMMGINDVKKQMVVWSVPTTIAWGIGGISVILANLIFGNDGSVFDLLFPIVMLASILFYIKLQNKNL
>NZ_LS483411.1|WP_111695612.1|1450883_1452227_-|phospholipase
MLKKICILLSLLAAFHVLAQDKVFKNIKPIQVTLLAEITAQGQKVNAVALEYEDNILSGSDLRKTYQISTALNGEEFIPRTILRAYVNNEPTLSAQPKIGKFVIIELDNQDKNADLYSLKTENNQSMQFKGRDKDGNVIVIEKKQINKVPQYYGEKLIYQINQIGYLKLTNGKTLDKIQLMQPAIFEHVKTPWLDQFAVKSVYLKDKANFLNYRIFTPHFETEKTYPLTIFLHGSGQVGSDNIAHLLSSKGAISTLQYEEGVVLAPQYQSVFDPFDDITKGHQGGIHWQTENRRDLVLKIIDETLMQYPQIDKTRIYLVGLSRGSEGAVKLLLTRPHFFAGALLMSGREAYTYEWVDGNATKENLSSIKDIPMWFFHSKEDKISPVEGSRINVNILKELHAPNVKYTEFTTEKVGDNGIANDNAHNTWDAVFNSPEVIQWLLHQKRR
>NZ_LS483411.1|WP_162690879.1|1449941_1450130_-|hypothetical-protein
MENINLYLGELVGTAFFMVLGLGVCANISLKNQECMGAVVYLPLVVGVINGVHCCYFWTTHR
>NZ_LS483411.1|WP_021035098.1|1449418_1449982_-|aquaporin-family-protein
MVSIAVIFGPLTGDHVNPAVTIDFWAVGKFPTELVLVYIIAQCIGAFIGALIVWLLFKDHLDEEDNQNCQLGSFTTIATNSNNLRNLLSEIVTTFSLLFILFALNHQQPTNGVAMFFVFTGVAGGVMSFGGLTSYAINPTRDFMPRLVHAIMPIKNKGSSNFDYAWVPVLRSVIGAMLAAWLCKAMF
>NZ_LS483411.1|WP_111695616.1|1461152_1462391_-|fimbrial-protein
MNKFVKTFQKLTALFIILNAIPQEVQADKQGVWHNECDTGGNHGCIRFPGGQSVVHYPKGPVLTERYLFPRDNPSLTLKPINMEKLIQALGKHEITMETYKIPKKSSSRNNSCFASELRLDEFIWNKIPNTSPTIFQLKEFPYLGFTFRIKTRLSGQPARVGENTRLQDWHNINDYFYTFRSGCGFTGEELRITPIMEITPIDLSHLVHGFQFPSGDIDLKLQNSYFGAFSLNGYSRSGPKPVVTEDAGTAINGSNVTIRLTAVTCNIKGVADYTRDFGTKKSSDITTPIKTSDVDIRVNCGSNAYINPWIVFTDANNLGNRSDTLKMIYKNNGAQTANVGIKLKQKNGNYISFGPDSPKKGTQNQIKLTKEFPQQNTYIISFTPELIKLDNSKKIEGGELEGRATYTLSYQ
>NZ_LS483411.1|WP_111695617.1|1462383_1463037_-|type-1-fimbrial-protein
MNKQGVKMRKTSLWAGVLFLLFGLPQGYAANHGKVTFSGKVLAARLCNITTETAGKTVDLGRVRSHQFTGEGTTVGGTDFTLSVRNCGEMPNTKNANRLKYYFVSPYAELKVITTNGLNVQYYLKNTVQNSGNKDSVGIQIFATSGSEAGKVIKVTKQTLPTDNSASSGYTGTQLGAKANGDTFDITLTAKFYAVTAGSSDKAGKVASEMTFEVFYE
>NZ_LS483411.1|WP_111695618.1|1463029_1463665_-|type-1-fimbrial-protein
MEDKPMKKLKKQGLFRQIIGLFSLLFVAPFSSASDGWVKFTVTIKNGGTCQVHSGYENKQVDLGTVYANELSTANQTAGEKDFDLWVEECGDLINETNKLKFVLMNTTNKTDLLAKGVLPNLETGANKDSVGVQLLTKQGNPVEIKYNASSSPTETLVLSPNGNTLGAEVVIGKKHAFKLPLKARFYAITNGKDDKAGDVRAEVIFAAFYE
>NZ_LS483411.1|WP_111695619.1|1463665_1466248_-|fimbrial-biogenesis-outer-membrane-usher-protein
MREFSFNPHLSLIGFLIGLAFFPLYTKAENVPNTPKESLNVEDEDVEFSAGFLNMGGNGSNIDVARFQQKNSVLPGEYPAAVWVNGKEKGEMTLRFRDNENANIPFAQLCFTPELEALLDLESAAIKRSPSENECVFIQEAIPDGKAVFNTGQQRLEFTIAQALTINRPRDYIAPSRWQTGDVAAFADYNINHSRYANQGSQSSQMFLNLRTGVNLGNWAFRHSGSKSWSQSEGQSYNTPYQTYETYVQRDFAPIRGLVTLGDFYTSGQVVEGFALRGIDISSDDRMLSPSQLGFAPRVQGIANSNAVVSIYQNGNIIYQTNVTPGPFVIDDLYSSGYNGDLTVEIKEADGKVRSFIVPFSNVAPLIRMGQFRYQLAAGRYRSGEEIYPDNVAQSMLQYGLYNNITINTGVTYSKNYLSGALGLGLNTPIGAFSVDSTWTRSTFLPHSLVDENGAMNTQPSVRKGYSLHGNYSINFNRTRTNITLAAYRYSSRDFYSLSDVINANHVIGKSFFSVLSPRPKNQYQLSIIQDFDKWGSLYLVGATRNYWNKSGSYHQYQLSYANRFKWLSYQIGFSQTIDRQSGQRDNQIYLSMSVPLGHNHSLSSNYARNSAGNSSSQIGINGSFGKNSQWSYGVYGNSGQEGYRNMSANMSYRNSYFDFDASASRDNRGSRQMSSNLSGVVVAHRHGLTFGESVGDSFAVVHADGAAGAEVNSGQGQMLDWFGNAIVPYTQPYRINEIGIDPQNLPLNIEFDGTEKKIIPRANSIHVIDFETKRNRLVLFNLTRTNGELLPMASEAYDEQGQFVGYVVQNGVLFAGGLQQPKGTIKVSWGNGEQNQCHFDYSVNLENATQMQQYEKVCQ
>NZ_LS483411.1|WP_111695620.1|1466358_1466646_-|hypothetical-protein
MKYIHFTVGLRPPYEVFGDAMKYIHFTVGLRPPYEALGDAMKYIHFTVGLRPPYEVFGDAMKYIHFTMGLRPPYEVLGRCDEIYSSNGYAQYLML
>NZ_LS483411.1|WP_111695621.1|1466679_1467387_-|fimbria/pilus-periplasmic-chaperone
MLSFSKKSIFISAILSCLFATFSAHASVIILGTRLIYPGNQSSLNVQLNNQDSSPALVQSWIEDKQGSQAQVPFIITPPVTRVEGNQGQTLRITFTGTQALPQDRESLYYFNLLDIPPKPSKAYLKDNPNYLQFSVRSRLKLFYRPSNLPYPPAEAYKKVSWQAKGGKLWADNPTPYYLTFTQATVGGKSAPEAVMVAPFSQGEFDVKGVNNGQKVKWSLINDYGGDVAGESTIN
>NZ_LS483411.1|WP_111695622.1|1467465_1468110_-|type-1-fimbrial-protein
MKFILKFLYRMFKMKKTILALLALGVVGANSAFATAVTTQNQPATHAKITVNGEVVTQTCEISTNDRNKVVTLDKVGTNSLKQTGNVAAQQLVTIHLENCTVTNGVHTPHVGTVHQTTQNKVSVTFNHTEKVDTANQFTLKNIETNDPATNVNIQFANINGNGLKIGQNDADAKLSVTDLSTTPAINFLARYYATGQSQAGKVKAEAELDLAYE
>NZ_LS483411.1|WP_111695623.1|1468324_1469380_-|molybdenum-ABC-transporter-ATP-binding-protein-ModC
MLQINVKKQLGQLALQANIQVPDQGVTAIFGLSGSGKTSLINLVSGLIQPDEGFIRLNDRTLVDMESQECLPTHLRKIGYVFQDARLFPHYSVKGNLRYGMKNVSQDDFNYIVDLLGITHLLKRYPLTLSGGEKQRVAIGRALLTDPDILLMDEPLSALDVPRKRELMQYLERLSKEINIPILYVTHSLDELLRLADRVVLMENGIVKAYDSVEKIWNSAIFAPWKGESEQSSVLALPVYLHNPPYKMTALSLGEQALWIHQVPANVSERVRVCIYSSDVSITLQKPEQTSIRNILRGKITQIEIQDSRVDLAVLVEGHKIWASISKWAQNELRFAVGQDVYVQIKAVSVM
>NZ_LS483411.1|WP_172453983.1|1469366_1470095_-|molybdate-ABC-transporter-permease-subunit
MITQFFSFFNLTPMEISAINLSLSVAVSSMLWSLPLAIFVAWLLARKNFYGKSLITGVIHLPLVLPPVVIGYLLLVAMGRNGFIGKYLYQWFGLSFGFSWKGAVLSSAVVAFPLVVRAIRLSLENIDIKLEQAAQTLGASAWRVFFTITLPLSLPGVLAGLVLGFARSLGEFGATITFVSNIAGETQTIPLAMYSFIQTPSAEEQTARLCLLAIILSLISLLLSEWLSKRMQKKLGQGNVAD
>NZ_LS483411.1|WP_111695624.1|1470217_1470982_-|molybdate-ABC-transporter-substrate-binding-protein
MKKLTKISTALLIAGLGFSFAASAKVTVFAAASMTDALQQVAKDYAKQNPKNEVVFSFASSSTLAKQIEEGAPADIFVSASNKWMKYLSEKDLTVKETEKVLVGNDLVLIAPAKSAVNSVDIAKGEWINALKDSYLSVGDPAHVPAGQYAEEALTKLNLWDKVKDRLARGKDVRGALALVERAEAPYGIVYSTDSKVSQQVKTVGVFPADSHKPVVYPVSIVKGHDNSDSRDFLKYLESDAAKKVLVGYGFSAK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LS483411_2	2.1\|618042\|34\|NZ_LS483411\|CRISPRCasFinder	618042-618075	34	MH572422	Microviridae sp. isolate SD_MC_8, complete genome	4166-4199	9	0.735

1. spacer 2.1|618042|34|NZ_LS483411|CRISPRCasFinder matches to MH572422 (Microviridae sp. isolate SD_MC_8, complete genome) position: , mismatch: 9, identity: 0.735

aaggcgaaagatttcgtggtacttaatggcgatg	CRISPR spacer
tatccgaatgattttgtggtacttaatggtaaaa	Protospacer
 *  **** *****.**************..* .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1022279 : 1096029

Mannheimia_phage(17.65%)

head,protease,tail,capsid,lysis,portal

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_110430592.1\|1022279_1022795_-\|protease	SprT family zinc-dependent metalloprotease	NA	NA	NA	NA
WP_005630438.1\|1023088_1024243_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.2e-127	62.7
WP_050848776.1\|1024754_1025219_+	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_172453995.1\|1025236_1026022_+	HAD family phosphatase	NA	NA	NA	NA
WP_111695486.1\|1026058_1027858_-	long-chain fatty acid--CoA ligase	A0A1V0SBX8	Catovirus	7.4e-44	26.0
WP_014326504.1\|1028050_1029070_-	type I glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_111695487.1\|1029320_1029947_+	guanylate kinase	K4JYM5	Abalone_herpesvirus	7.5e-20	35.6
WP_111695488.1\|1030009_1030276_+	DNA-directed RNA polymerase subunit omega	NA	NA	NA	NA
WP_111695489.1\|1030819_1032934_+	bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase	A0A1B1IUF0	uncultured_Mediterranean_phage	2.5e-11	38.8
WP_111695490.1\|1032930_1035012_+	ATP-dependent DNA helicase RecG	NA	NA	NA	NA
WP_111695491.1\|1035042_1035852_+	glutamate racemase	NA	NA	NA	NA
WP_021035422.1\|1036062_1037208_+	FMN-dependent L-lactate dehydrogenase LldD	NA	NA	NA	NA
WP_111695492.1\|1043313_1043541_+	hypothetical protein	NA	NA	NA	NA
WP_041175358.1\|1043550_1044063_+	hypothetical protein	NA	NA	NA	NA
WP_021035420.1\|1044326_1045256_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005670246.1\|1045981_1046311_+	AzlD domain-containing protein	NA	NA	NA	NA
WP_005632089.1\|1046413_1046647_+	YgjV family protein	NA	NA	NA	NA
WP_021035419.1\|1046722_1048303_-	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	4.3e-32	27.3
WP_005667099.1\|1048533_1049322_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_021035418.1\|1049401_1051381_+	exoribonuclease II	Q0GXV6	Lactococcus_phage	1.1e-24	25.1
WP_111695493.1\|1051807_1059013_+	Hia/Hsf adhesin N-terminal domain-containing protein	NA	NA	NA	NA
WP_021035416.1\|1059249_1059891_+	5-oxoprolinase subunit PxpB	NA	NA	NA	NA
WP_021035415.1\|1059887_1060817_+	5-oxoprolinase/urea amidolyase family protein	NA	NA	NA	NA
WP_021035414.1\|1060803_1061541_+	5-oxoprolinase subunit PxpA	NA	NA	NA	NA
WP_111695494.1\|1061584_1062778_+	divalent metal cation transporter	NA	NA	NA	NA
WP_021035412.1\|1062858_1064193_-	argininosuccinate synthase	A0A140XAJ5	Dickeya_phage	8.4e-53	79.4
WP_021035411.1\|1064369_1065242_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0M4JBD3	Mollivirus	7.4e-50	35.7
WP_050949442.1\|1065407_1067756_-	penicillin-binding protein 1B	NA	NA	NA	NA
WP_021035409.1\|1067762_1068116_-	YacL family protein	NA	NA	NA	NA
WP_021035408.1\|1068117_1068462_-	iron-sulfur cluster insertion protein ErpA	A0A2H4N7M3	Lake_Baikal_phage	1.7e-26	48.6
WP_021035407.1\|1068598_1069405_+	type I methionyl aminopeptidase	NA	NA	NA	NA
WP_021035406.1\|1069497_1072089_+	bifunctional uridylyltransferase/uridylyl-removing protein GlnD	NA	NA	NA	NA
WP_111695495.1\|1072878_1073946_+	UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase	NA	NA	NA	NA
WP_021035403.1\|1074242_1074791_-	oligoribonuclease	Q8B5Y0	Diachasmimorpha_longicaudata_entomopoxvirus	1.6e-29	40.7
WP_021035402.1\|1074861_1075902_+	small ribosomal subunit biogenesis GTPase RsgA	NA	NA	NA	NA
WP_005654341.1\|1076060_1076318_+	phosphocarrier protein Hpr	NA	NA	NA	NA
WP_011272760.1\|1076397_1078125_+	phosphoenolpyruvate-protein phosphotransferase PtsI	NA	NA	NA	NA
WP_005688036.1\|1078184_1078685_+	PTS glucose transporter subunit IIA	NA	NA	NA	NA
WP_005688034.1\|1078822_1078918_+	hypothetical protein	NA	NA	NA	NA
WP_005688032.1\|1079032_1079398_+	YgiW/YdeI family stress tolerance OB fold protein	A0A1I9LJU6	Stx_converting_phage	5.9e-09	34.2
WP_014550655.1\|1079461_1080127_+	response regulator	NA	NA	NA	NA
WP_021035401.1\|1080123_1081479_+	two-component system sensor histidine kinase QseC	W8CYF6	Bacillus_phage	5.4e-15	26.5
WP_041175356.1\|1081744_1083772_+	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	2.1e-18	24.8
WP_021035399.1\|1083808_1085284_-	leucyl aminopeptidase	Q6GYZ8	Mycoplasma_phage	3.2e-45	35.7
WP_005664886.1\|1085391_1086495_+	LPS export ABC transporter permease LptF	NA	NA	NA	NA
WP_021035398.1\|1086491_1087568_+	LPS export ABC transporter permease LptG	NA	NA	NA	NA
WP_021035397.1\|1087761_1090032_+	5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase	NA	NA	NA	NA
WP_021035396.1\|1090681_1091692_-\|portal	phage portal protein	Q19UT6	Mannheimia_phage	2.3e-119	61.5
WP_111695496.1\|1093651_1094458_+\|capsid	GPO family capsid scaffolding protein	A0A0M3LNM2	Mannheimia_phage	3.3e-60	58.1
WP_111695497.1\|1095090_1095597_+\|head	head completion/stabilization protein	A0A0M3LNL8	Mannheimia_phage	1.1e-32	51.0
WP_042603529.1\|1095596_1095806_+\|tail	tail protein X	NA	NA	NA	NA
WP_048949896.1\|1095807_1096029_+\|lysis	lysis protein	NA	NA	NA	NA

DBSCAN-SWA_2

1745409 : 1766948

Haemophilus_phage(60.0%)

head,protease,plate,tail,terminase,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111695716.1\|1745409_1747254_+	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	4.8e-22	29.3
WP_005651690.1\|1747331_1747610_-	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_111695717.1\|1748057_1749698_+\|terminase	phage terminase large subunit	B7SDN0	Haemophilus_phage	8.5e-249	78.2
WP_021034885.1\|1749778_1751401_+	DUF935 domain-containing protein	B7SDN1	Haemophilus_phage	7.0e-203	68.3
WP_111695718.1\|1751384_1752692_+\|capsid	minor capsid protein	A0A0M3LSH7	Mannheimia_phage	1.6e-160	67.2
WP_021034883.1\|1752814_1753231_+	phage virion morphogenesis protein	B7SDN8	Haemophilus_phage	2.1e-47	66.7
WP_021034882.1\|1753513_1754551_+\|protease	phage protease	B7SDN9	Haemophilus_phage	7.2e-68	46.7
WP_021034881.1\|1754550_1755474_+\|head	Mu-like prophage major head subunit gpT family protein	B7SDP1	Haemophilus_phage	1.4e-134	75.2
WP_021034880.1\|1755537_1755843_+	hypothetical protein	B7SDP3	Haemophilus_phage	6.9e-19	47.0
WP_021034879.1\|1755852_1756284_+	DUF1320 domain-containing protein	B7SDP4	Haemophilus_phage	1.3e-36	60.9
WP_021034878.1\|1756267_1756930_+	DUF1834 family protein	A0A0M3LQJ7	Mannheimia_phage	1.2e-44	45.0
WP_041175294.1\|1756901_1757084_+	DUF2635 domain-containing protein	A0A0M3LQM9	Mannheimia_phage	1.0e-09	63.3
WP_021034876.1\|1757076_1758492_+\|tail	phage tail sheath subtilisin-like domain-containing protein	B7SDP8	Haemophilus_phage	1.1e-156	62.6
WP_021034875.1\|1758501_1758873_+	hypothetical protein	A0A0M3LRV6	Mannheimia_phage	1.2e-36	65.0
WP_021034874.1\|1758872_1759214_+	hypothetical protein	A0A0M3LSI2	Mannheimia_phage	1.8e-20	50.5
WP_021034873.1\|1759228_1759435_+	hypothetical protein	NA	NA	NA	NA
WP_021034870.1\|1761762_1763097_+	DNA circularization N-terminal domain-containing protein	F6MIL2	Haemophilus_phage	6.3e-109	45.6
WP_021034869.1\|1763086_1764211_+	bacteriophage Mu P family protein	F6MIL3	Haemophilus_phage	1.4e-146	72.7
WP_021034868.1\|1764220_1764856_+\|plate	phage baseplate assembly protein V	A0A0M3LPA3	Mannheimia_phage	4.7e-62	58.3
WP_041175293.1\|1764925_1765276_+	phage GP46 family protein	A0A0M3LQK5	Mannheimia_phage	1.2e-43	73.3
WP_111695719.1\|1765290_1766355_+\|plate	baseplate J/gp47 family protein	F6MIL6	Haemophilus_phage	2.6e-129	67.1
WP_172454002.1\|1766351_1766948_+	DUF2313 domain-containing protein	F6MIL7	Haemophilus_phage	2.3e-66	63.0

DBSCAN-SWA_3

1792311 : 1800851

Escherichia_phage(71.43%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021034845.1\|1792311_1792965_+	ABC transporter ATP-binding protein	M1HXU1	Acanthocystis_turfacea_Chlorella_virus	9.3e-05	25.6
WP_111695725.1\|1793131_1793662_+	superoxide dismutase family protein	Q9MC02	Salmonella_phage	2.6e-45	59.7
WP_021034843.1\|1793751_1794030_-	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_005656013.1\|1794038_1794401_-	membrane protein	NA	NA	NA	NA
WP_014550950.1\|1794375_1795485_-	transglutaminase family protein	NA	NA	NA	NA
WP_111695726.1\|1795738_1798159_+	molybdopterin-dependent oxidoreductase	A0A077SK27	Escherichia_phage	4.8e-224	50.5
WP_111695727.1\|1798169_1798787_+	dimethylsulfoxide reductase subunit B	A0A077SL61	Escherichia_phage	3.7e-72	57.3
WP_005669794.1\|1798788_1799628_+	dimethyl sulfoxide reductase anchor subunit	A0A077SK59	Escherichia_phage	1.3e-19	33.2
WP_005669792.1\|1799739_1800351_+	Tat proofreading chaperone DmsD	A0A077SLS7	Escherichia_phage	3.0e-21	32.5
WP_005669790.1\|1800350_1800851_+	ferredoxin-type protein NapF	A0A077SLP0	Escherichia_phage	9.2e-13	31.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LS483411

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection