CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483415	Streptococcus pyogenes strain NCTC8304 chromosome 1	2 crisprs	csm6,cas3,DEDDh,csa3	1	5	6	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483415_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483415_1

779647-780012

Orphan

II-A

Consensus_repeat	Method
GTTTTAGAGCTATGNTGTTTTGAATGGTCCCAAAAC	CRT
GTTTTAGAGCTATGCTGTTTTGAATGGTCCCAAAAC	PILER-CR

5 spacers

The CRISPR arrays of NZ_LS483415_1

>merge|NZ_LS483415|1|779647-780012|CRT,PILER-CR
TTTAACTTGCTATGCTGTTTTGAATGGTCCCAAAACCTTACGAGCTGAGTTTACTCGTAGTAATCAGTTTTAGAGCTATGCTGTTTTGAATGGTCCCAAAACCACTGATTGGACAAAGAATGCTCCAGTCCGGTTTTAGAGCTATGCTGTTTTGAATGGTCCCAAAACGATTAGCTCAAGCATGCCTTTATAAATGTTGTTTTAGAGCTATGTTGTGTTGAATGGTCCCAAAACCAGCTTGGATTTAATAGCAGACCATGTTTTGTTTTAGAGCTATGTTGTTTTGGATGGTCCCAAAACGCACGAGTTTAACTCCCTTATTATTAGCTTGTTTTAGAGCTATGCTGTTTTGAATGGTCTCCATTC

>NZ_LS483415|1|1|779647-780012|CRT
TTTAACTTGCTATGCTGTTTTGAATGGTCCCAAAAC	CTTACGAGCTGAGTTTACTCGTAGTAATCA
GTTTTAGAGCTATGCTGTTTTGAATGGTCCCAAAAC	CACTGATTGGACAAAGAATGCTCCAGTCCG
GTTTTAGAGCTATGCTGTTTTGAATGGTCCCAAAAC	GATTAGCTCAAGCATGCCTTTATAAATGTT
GTTTTAGAGCTATGTTGTGTTGAATGGTCCCAAAAC	CAGCTTGGATTTAATAGCAGACCATGTTTT
GTTTTAGAGCTATGTTGTTTTGGATGGTCCCAAAAC	GCACGAGTTTAACTCCCTTATTATTAGCTT
GTTTTAGAGCTATGCTGTTTTGAATGGTCTCCATTC

>NZ_LS483415|1|1|779713-779946|PILER-CR
GTTTTAGAGCTATGCTGTTTTGAATGGTCCCAAAAC	CACTGATTGGACAAAGAATGCTCCAGTCCG
GTTTTAGAGCTATGCTGTTTTGAATGGTCCCAAAAC	GATTAGCTCAAGCATGCCTTTATAAATGTT
GTTTTAGAGCTATGTTGTGTTGAATGGTCCCAAAAC	CAGCTTGGATTTAATAGCAGACCATGTTTT
GTTTTAGAGCTATGTTGTTTTGGATGGTCCCAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483415.1\|WP_002984844.1\|786477_787287_+\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226238
NZ_LS483415.1\|WP_164552689.1\|770719_772063_-\|DUF1727-domain-containing-protein	unknown	unknown	gnl\|CDD\|223840
NZ_LS483415.1\|WP_111705592.1\|769928_770720_-\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
NZ_LS483415.1\|WP_011017728.1\|790681_791728_+\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270264
NZ_LS483415.1\|WP_111705596.1\|784299_785319_+\|YeiH-family-putative-sulfate-export-transporter	unknown	unknown	gnl\|CDD\|225411
NZ_LS483415.1\|WP_002989935.1\|785525_785951_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
NZ_LS483415.1\|WP_002984857.1\|773012_773969_+\|YbbR-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|227193
NZ_LS483415.1\|WP_020905134.1\|778097_778862_+\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_LS483415.1\|WP_014635437.1\|778861_779494_+\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
NZ_LS483415.1\|WP_002984858.1\|772164_773016_+\|TIGR00159-family-protein	unknown	unknown	gnl\|CDD\|224539
NZ_LS483415.1\|WP_111705597.1\|788246_789896_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NZ_LS483415.1\|WP_011017717.1\|775501_776143_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483415.1\|WP_011184463.1\|774022_775378_+\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NZ_LS483415.1\|WP_111685729.1\|783732_784170_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_LS483415.1\|WP_002984836.1\|789899_790688_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|227095
NZ_LS483415.1\|WP_002989931.1\|787283_788111_+\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	unknown	unknown	gnl\|CDD\|226239
NZ_LS483415.1\|WP_002989934.1\|785969_786461_+\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|225976
NZ_LS483415.1\|WP_111705594.1\|776205_777336_+\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_LS483415.1\|WP_020905133.1\|777345_778098_+\|acyl-[acyl-carrier-protein]-thioesterase	unknown	unknown	gnl\|CDD\|226401
NZ_LS483415.1\|WP_010922253.1\|780654_782487_+\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462

Protein	Function_ID	Function_description	E-value
NZ_LS483415.1\|WP_002989931.1\|787283_788111_+\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	gnl\|CDD\|226239	COG3716, ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism].	1.55707e-109
NZ_LS483415.1\|WP_164552689.1\|770719_772063_-\|DUF1727-domain-containing-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	1.46231e-109
NZ_LS483415.1\|WP_111705592.1\|769928_770720_-\|type-1-glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	1.06082e-141
NZ_LS483415.1\|WP_011017728.1\|790681_791728_+\|extracellular-solute-binding-protein	gnl\|CDD\|270264	cd13546, PBP2_BitB, Substrate binding domain of a putative iron transporter BitB, a member of the type 2 periplasmic binding fold superfamily. The substrate domain of this group shows a high homology to the periplasmic component of ferric iron transporter (Fbp), but its biochemical characterization has not been performed. The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria from the Pasteurellaceae and Neisseriaceae families and is critical for survival of these pathogens within the host. After binding iron with high affinity, Fbp interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The ferric iron-binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.33783e-91
NZ_LS483415.1\|WP_111705596.1\|784299_785319_+\|YeiH-family-putative-sulfate-export-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	1.34952e-103
NZ_LS483415.1\|WP_002989935.1\|785525_785951_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	3.64459e-31
NZ_LS483415.1\|WP_002984857.1\|773012_773969_+\|YbbR-like-domain-containing-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	3.12847e-114
NZ_LS483415.1\|WP_020905134.1\|778097_778862_+\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.59897e-126
NZ_LS483415.1\|WP_014635437.1\|778861_779494_+\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	1.90272e-87
NZ_LS483415.1\|WP_002984858.1\|772164_773016_+\|TIGR00159-family-protein	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	2.09715e-101
NZ_LS483415.1\|WP_002984844.1\|786477_787287_+\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	gnl\|CDD\|226238	COG3715, ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism].	3.81104e-76
NZ_LS483415.1\|WP_011184463.1\|774022_775378_+\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_LS483415.1\|WP_111685729.1\|783732_784170_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	1.80871e-84
NZ_LS483415.1\|WP_002984836.1\|789899_790688_+\|response-regulator-transcription-factor	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	5.79862e-82
NZ_LS483415.1\|WP_111705597.1\|788246_789896_+\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	1.38139e-77
NZ_LS483415.1\|WP_002989934.1\|785969_786461_+\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	gnl\|CDD\|225976	COG3444, COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB [Carbohydrate transport and metabolism].	8.80769e-55
NZ_LS483415.1\|WP_111705594.1\|776205_777336_+\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_LS483415.1\|WP_020905133.1\|777345_778098_+\|acyl-[acyl-carrier-protein]-thioesterase	gnl\|CDD\|226401	COG3884, FatA, Acyl-ACP thioesterase [Lipid metabolism].	1.32711e-106
NZ_LS483415.1\|WP_010922253.1\|780654_782487_+\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0

>NZ_LS483415.1|WP_014635437.1|778861_779494_+|TIGR01906-family-membrane-protein
MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVFMSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLLYPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHKVLFVGDSSWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE
>NZ_LS483415.1|WP_020905134.1|778097_778862_+|TIGR01457-family-HAD-type-hydrolase
MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQEKGIPYLLVTNNTTRTPAMVQSMLANQFNVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIAAAGYVEELENPAYVVVGLDSQVTYEMLAIATLAIQKGALFIGTNPDLNIPTERGLMPGAGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQNDIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL
>NZ_LS483415.1|WP_020905133.1|777345_778098_+|acyl-[acyl-carrier-protein]-thioesterase
MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGRSNNNLLVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGGLLVDILAYFALLNPDTRKVATIPEDLVAPFKTDFVKKLYRVPKMPLLEQSIDRDYYVRYFDIDMNGHVNNSKYLDWMYDVLGCAFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQLNSYHQITSDGQLNAQAMIEWRAIKQTESEID
>NZ_LS483415.1|WP_111705594.1|776205_777336_+|oxygen-independent-coproporphyrinogen-III-oxidase
MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLRALIQEFDSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTLEKITVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKAAGFHNISIDLIYALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQNRVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGVSFEERYGNIARELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD
>NZ_LS483415.1|WP_011017717.1|775501_776143_+|hypothetical-protein
MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTQKEDTQNRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAVNEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLTDMQEKLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSKP
>NZ_LS483415.1|WP_011184463.1|774022_775378_+|phosphoglucosamine-mutase
MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN
>NZ_LS483415.1|WP_002984857.1|773012_773969_+|YbbR-like-domain-containing-protein
MKRFLNSRPWLGMVSVFFAILLFLTAASSNHNNSSSQIYSPIETYTHSLKDVPIDMKYDSDKYFISGYSYGAEVYLTSTNRIKLDSEVNNDTRNFKIVADLTHSHPGTVSVNLRVENLPSGVTATVSPDKISVTIGKKESKVFPVRGSVDAKQIANGYEISKIETGVNKVEVTSDESTIALIDHVVAKLPDDQVLDRNYSSRVTLQAVSADGTILASAIDPAKTNLSVAVKKITKSVPIRVEAVGMMDDSLSDIQYKLSKQTAVISGSREVLEDIDEIIAEVNISDVTKNTSKTVSLSSSQVSIEPSVVTVQLTTTKK
>NZ_LS483415.1|WP_002984858.1|772164_773016_+|TIGR00159-family-protein
MNNLSSIDIKFLLSLFADPWLLAVHLLDILIVAYLIYRFIKALTGTKIMSLVQGVIFFLVLRFIAEWIGFTTITYLMNQVITYGVIAGVVIFTPEIRAGLEKFGRSTQVFLQKQYVSSESALVDALIKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPLNADISSQLLINIFIPNTPLHDGAVIVGQNKIVAACAYLPLSESKAISKEFGTRHRAAIGLSENSDALTIIVSEETGAISVTRKGQFLHDLSTDEFETVLRTYLMSDSNVTLPWYKKILGGKSK
>NZ_LS483415.1|WP_164552689.1|770719_772063_-|DUF1727-domain-containing-protein
MKMKTLLGIIAGKAAQSILTKLGRGSTYPGRLALACNKDILKDLSKDYDIVVVTGTNGKTLTTALTVGILKEAFGEIITNPSGANMITGITSTFLAAKKGKSGRQIAVLEIDEASLPRITTYLKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGARNAPKATILANGDSPIFSSKDIVNPVQYYGFDTAKHAPQLAHYNTEGILCPKCEHILQYRLNTYANLGDFICLNCGFKRPQLDYRLTELTTITNHSSEFIIDDQDYKINVGGLYNIYNALAAVSVAEFFGVSPEKIKAGFNKSKAVFGRQETFTIGDKSCTLILIKNPVGASQALEMIQLADYPFSLSVLLNANYADGIDTSWIWDANFELITQMPITEINAGGVRHSEIARRLRVTGFDDTKIKQAEKLEQIIETIEKQEAKHAYLLATYTAMLEFRSLLADRHVVEKEMI
>NZ_LS483415.1|WP_111705592.1|769928_770720_-|type-1-glutamine-amidotransferase
MTYTSLKSPENQDYIYDLNIAHLYGNLMNTYGDNGNILMLKYVAEKLEARVTVDIVSINDTFEQDDYDIVFFGGGQDYEQSIVAKDLPSKKAALADYIANNKVVLAICGGFQLLGQYYVQANGVKIDGLGIMGHYTLNQHQNRFIGDIKIHNDEFNETYYGFENHQGRTFLSGDEKPLGRVVYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVNLAYRLVTTALKKKYGSAISLPSYDDILKQEITEEYADLKSKASFNKV
>NZ_LS483415.1|WP_010922253.1|780654_782487_+|elongation-factor-4
MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDTKK
>NZ_LS483415.1|WP_111685729.1|783732_784170_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
METSEELKQRIGDLSYEVTQHAATESPFTGEYDHFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET
>NZ_LS483415.1|WP_111705596.1|784299_785319_+|YeiH-family-putative-sulfate-export-transporter
MSTHLRKLPGLLLCLLLALPAWCLGRLFLIIGAPVFAILLGMLLALFYEHRDKTKEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSLPIIVSTIATALLVAYGSQKWLRLDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNMLAALLFPSLGQLLGLSNEGFAIFAGTAVNDTSSVTATATAWDAIHHSNTLDGATIVKLTRTLAILPITLGLSLYRAKKEHDIVTEENFSLRKSFPRFILFFLLASLITTLMTSLGVSADSFHSLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQLSLGIW
>NZ_LS483415.1|WP_002989935.1|785525_785951_+|PTS-sugar-transporter-subunit-IIA
MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYTSQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLVFLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD
>NZ_LS483415.1|WP_002989934.1|785969_786461_+|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB
MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQMTLKMAVPNGMKLLIRSVEDSIKLFNDPRATDKRIFVIVNSVKDACAIAKEVPDLEAVNVANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQLVN
>NZ_LS483415.1|WP_002984844.1|786477_787287_+|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC
MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDMKVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGMLAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILVGSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYLKLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA
>NZ_LS483415.1|WP_002989931.1|787283_788111_+|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID
MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTLLPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAITAVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHYYSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKGAKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC
>NZ_LS483415.1|WP_111705597.1|788246_789896_+|sensor-histidine-kinase
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRYHRLISKQEALLDDLGKNSLLPFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPSQDLLFASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGHYLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLAVPKLFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHYQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE
>NZ_LS483415.1|WP_002984836.1|789899_790688_+|response-regulator-transcription-factor
MYKLVIIEDEHIIRKWLRYAIDYKALDILVIGEAKDGKEGAVLIKESQPDIVLTDINMPIMTAFDMFEATKDQTYAKIILSGYADFPNARSAIHYGVLEFLTKPIEKAALWECLQTIIAKIEKQKGSNQKTDACVYIPLPQMTDQIPEVVKDILEWVHAHFQDKISTSRLAHDLGYSESYIYQNIKKHLQMPLSDYINQYRINQAIQLMQQEPDLMVYEIAQAVGIYDYRYFDRVFKKYLGQTVKAFKEEHFMKDTDRSKPC
>NZ_LS483415.1|WP_011017728.1|790681_791728_+|extracellular-solute-binding-protein
MLKLKRKWLLSFLLVIIILAIVNIAMYIFSSSKKDSAKELVILTPNSQTILTGTIPAFEEKYGVKVRLIQGGTGQLIDQLGRKDKPLNADIFFGGNYTQFESHKDLFESYVSPQVSTVISDYQLPSHRATPYTINGSVLIVNNELARGLHITSYEDLLQPALKGKIAFADPNSSSSAFSQLTNILLAKGGYTSSEAWEYVKRLLLSMNSIRATSSSDVYESVAEGKMIVGLTYEDPCINLQKSGANVSIVYPDEGTVFVPSSVAIIKKAKAMKEAKQFINFILSSDVQNAFGQSTSNRPIRRDAQTSHEMKPLDEIITLKEDYGYVTRHKKKILNTYNRLHEALERGK

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Crispr_ID: NZ_LS483415_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483415_2

1056831-1056938

Orphan

Consensus_repeat	Method
AGGCGTCACTAGCAGCGTTATCTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483415_2

>merge|NZ_LS483415|2|1056831-1056938|CRISPRCasFinder
AGGCGTCACTAGCAGCGTTATCTGATTGAACTGCTGCAGCTTCTTCTGATTGTAAAGTGTCTGCTTGATCCGCTAATGCTTCTAAGGCGTCACTAGCAGCGTTATCCG

>NZ_LS483415|2|1|1056831-1056938|CRISPRCasFinder
AGGCGTCACTAGCAGCGTTATCTG	ATTGAACTGCTGCAGCTTCTTCTGATTGTAAAGTGTCTGCTTGATCCGCTAATGCTTCTA
AGGCGTCACTAGCAGCGTTATCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483415.1\|WP_111705662.1\|1053228_1054512_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|226594
NZ_LS483415.1\|WP_002984115.1\|1045201_1045603_-\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|224961
NZ_LS483415.1\|WP_002984109.1\|1047848_1049300_-\|LCP-family-protein	unknown	unknown	gnl\|CDD\|224235
NZ_LS483415.1\|WP_010922414.1\|1066220_1066718_-\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|224867
NZ_LS483415.1\|WP_164552703.1\|1049991_1051275_-\|3-phosphoshikimate-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|235037
NZ_LS483415.1\|WP_110002905.1\|1054520_1055063_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_LS483415.1\|WP_011017929.1\|1068067_1068694_-\|uridine-kinase	unknown	unknown	gnl\|CDD\|235492
NZ_LS483415.1\|WP_002989295.1\|1057589_1058849_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|183779
NZ_LS483415.1\|WP_111705665.1\|1060755_1063134_-\|leucine-rich-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|227223
NZ_LS483415.1\|WP_011106727.1\|1046411_1047800_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|225174
NZ_LS483415.1\|WP_002989257.1\|1067724_1067988_-\|DUF1294-domain-containing-protein	unknown	unknown	gnl\|CDD\|225863
NZ_LS483415.1\|WP_002984073.1\|1064550_1066221_-\|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl\|CDD\|235505
NZ_LS483415.1\|WP_009880588.1\|1049507_1049999_-\|shikimate-kinase	unknown	unknown	gnl\|CDD\|234654
NZ_LS483415.1\|WP_111705664.1\|1059022_1060219_-\|methionine-adenosyltransferase	unknown	unknown	gnl\|CDD\|235374
NZ_LS483415.1\|WP_111705658.1\|1045687_1046302_-\|nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|350158
NZ_LS483415.1\|WP_012560785.1\|1064252_1064456_-\|DUF3272-domain-containing-protein	unknown	unknown	gnl\|CDD\|314526
NZ_LS483415.1\|WP_111705661.1\|1052352_1053213_-\|methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|180918
NZ_LS483415.1\|WP_111705660.1\|1051385_1052351_-\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
NZ_LS483415.1\|WP_011017924.1\|1063336_1064278_+\|bifunctional-biotin--[acetyl-CoA-carboxylase]-synthetase/biotin-operon-repressor	unknown	unknown	gnl\|CDD\|237010
NZ_LS483415.1\|WP_002989260.1\|1066862_1067672_+\|PrsW-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|225217

Protein	Function_ID	Function_description	E-value
NZ_LS483415.1\|WP_111705662.1\|1053228_1054512_-\|CBS-domain-containing-protein	gnl\|CDD\|226594	COG4109, COG4109, Predicted transcriptional regulator containing CBS domains [Transcription].	0
NZ_LS483415.1\|WP_002984115.1\|1045201_1045603_-\|PaaI-family-thioesterase	gnl\|CDD\|224961	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis, transport, and catabolism].	1.21804e-24
NZ_LS483415.1\|WP_002984109.1\|1047848_1049300_-\|LCP-family-protein	gnl\|CDD\|224235	COG1316, LytR, Transcriptional regulator [Transcription].	3.50658e-64
NZ_LS483415.1\|WP_010922414.1\|1066220_1066718_-\|GAF-domain-containing-protein	gnl\|CDD\|224867	COG1956, COG1956, GAF domain-containing protein [Signal transduction mechanisms].	8.27061e-83
NZ_LS483415.1\|WP_164552703.1\|1049991_1051275_-\|3-phosphoshikimate-1-carboxyvinyltransferase	gnl\|CDD\|235037	PRK02427, PRK02427, 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional.	0
NZ_LS483415.1\|WP_110002905.1\|1054520_1055063_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	4.45215e-31
NZ_LS483415.1\|WP_011017929.1\|1068067_1068694_-\|uridine-kinase	gnl\|CDD\|235492	PRK05480, PRK05480, uridine/cytidine kinase; Provisional.	1.30464e-134
NZ_LS483415.1\|WP_002989295.1\|1057589_1058849_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl\|CDD\|183779	PRK12830, PRK12830, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Reviewed.	0
NZ_LS483415.1\|WP_111705665.1\|1060755_1063134_-\|leucine-rich-repeat-domain-containing-protein	gnl\|CDD\|227223	COG4886, COG4886, Leucine-rich repeat (LRR) protein [Function unknown].	1.50348e-28
NZ_LS483415.1\|WP_011106727.1\|1046411_1047800_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	2.62378e-180
NZ_LS483415.1\|WP_002989257.1\|1067724_1067988_-\|DUF1294-domain-containing-protein	gnl\|CDD\|225863	COG3326, COG3326, Predicted membrane protein [Function unknown].	6.73707e-28
NZ_LS483415.1\|WP_002984073.1\|1064550_1066221_-\|DNA-polymerase-III-subunit-gamma/tau	gnl\|CDD\|235505	PRK05563, PRK05563, DNA polymerase III subunits gamma and tau; Validated.	0
NZ_LS483415.1\|WP_009880588.1\|1049507_1049999_-\|shikimate-kinase	gnl\|CDD\|234654	PRK00131, aroK, shikimate kinase; Reviewed.	6.48408e-63
NZ_LS483415.1\|WP_111705664.1\|1059022_1060219_-\|methionine-adenosyltransferase	gnl\|CDD\|235374	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated.	0
NZ_LS483415.1\|WP_111705658.1\|1045687_1046302_-\|nucleoside-phosphorylase	gnl\|CDD\|350158	cd09007, NP-I_spr0068, uncharacterized subfamily of the nucleoside phosphorylase-I family. This subfamily is composed of uncharacterized members including Streptococcus pneumoniae hypothetical protein spr0068. The nucleoside phosphorylase-I (NP-I) family members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases such as purine nucleoside phosphorylase (PNP, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases such as AMP nucleosidase (AMN, EC 3.2.2.4) and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). Members of the NP-I family display different physiologically relevant quaternary structures: hexameric (trimer-of-dimers arrangement of Shewanella oneidensis MR-1 UP); homotrimeric (human PNP and Escherichia coli PNPII or XapA); hexameric (with some evidence for co-existence of a trimeric form) such as E. coli PNPI (DeoD); or homodimeric such as human and Trypanosoma brucei UP. The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	4.44123e-87
NZ_LS483415.1\|WP_012560785.1\|1064252_1064456_-\|DUF3272-domain-containing-protein	gnl\|CDD\|314526	pfam11676, DUF3272, Protein of unknown function (DUF3272). This family of proteins with unknown function appears to be restricted to Streptococcus.	2.21156e-22
NZ_LS483415.1\|WP_111705661.1\|1052352_1053213_-\|methionyl-aminopeptidase	gnl\|CDD\|180918	PRK07281, PRK07281, methionyl aminopeptidase.	0
NZ_LS483415.1\|WP_111705660.1\|1051385_1052351_-\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	3.29674e-56
NZ_LS483415.1\|WP_011017924.1\|1063336_1064278_+\|bifunctional-biotin--[acetyl-CoA-carboxylase]-synthetase/biotin-operon-repressor	gnl\|CDD\|237010	PRK11886, PRK11886, bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA.	3.03251e-144
NZ_LS483415.1\|WP_002989260.1\|1066862_1067672_+\|PrsW-family-intramembrane-metalloprotease	gnl\|CDD\|225217	COG2339, prsW, Membrane proteinase, regulator of anti-sigma factor [Posttranslational modification, protein turnover, chaperones].	2.0574e-58

>NZ_LS483415.1|WP_110002905.1|1054520_1055063_-|GNAT-family-N-acetyltransferase
MDIWTKLAVFAFFETPKVILRPFRYEDHWDFYSMVNDTKNLYYVFPEQKTKAASDYLLVHSFLKFPLGQWAIEDKATHQVIGSIRIEHYDAKTRCADIGYFLNYAFWGQGIMTEVVIKLVYLSFHEFGLKTLRIITHLENKASQKVAKKAGFQLKTCFKGSDRNTHKICIYKMYQLTNDR
>NZ_LS483415.1|WP_111705662.1|1053228_1054512_-|CBS-domain-containing-protein
MSKHQDILDYLEKLAIGKKVSVRSISNHLKVSDGTAYRAIKEAENRGIVETKPRSGTVRIEKKGRVRIDRLTYSEIARISNSEVLAGHAGLGHEFSRFSIGAMTQQNIRRYLVKGGLLIVGDRETIQLLALENHNAILVTGGFPVSKRVIEMANNQRIPVMVTHYDTFTVATMINHALSNIRIKTDLKTVEQVMIPITDYGYLCEDSSVEEFNTLIKKTRQVRFPVLDYKRKVIGVVSMRDVVDQLPTTKLTKVMSKNPITARPNTSLANISQKMIFEDLNMLPVTDEENNLLGMITRRQAMENLPNHQPNNPYTYSEQILSNLEETVDYYQVVVEPTMIDSAGNMSNGVISEFLKEISIRALTKKHQKNIIIEQMMVYFLHAIQIEDELKIYPKIITENRRSSTIDIEIFVDDQVIAKAIITTKIN
>NZ_LS483415.1|WP_111705661.1|1052352_1053213_-|methionyl-aminopeptidase
MITLKSAREIEAMDRAGDFLAGIHIGLRDIIKPGVDMWEVEAYVRRRCKEDNVLPLQIGVDGHMMDYPYATCCGLNDEVAHAFPRHYILKEGDLLKVDMVLSEPLDKSIVDVAALDFDNVPEMKKWTGSYTGGLADSCWAYAVGTPSDEIKQLMDVTKEAMYRGIEKAVIGNRIGDIGAAVQEYAESFGYGVVRDLVGHGVGPTMHEEPMVPNYGTAGRGLRLKEGMVLTVEPMINTGIWEIDTDIKTGWAHKTLDGGLSCQYEHQFVITKDGPVILTSQGEERTY
>NZ_LS483415.1|WP_111705660.1|1051385_1052351_-|YihY/virulence-factor-BrkB-family-protein
MAEKKWFDKVLSKWQYEPIQVFMRHLQSAEMDLSAIAVAYYLILTVFPLIVIAANIFPYLNIDIADLLRLMKQNLPKDIFRPASAIVENIFSKPSGSVLGVATLTGLWTMSRSLTSLQKAINKAYGASQHRDFFIGHLVGLLTSLIILFLLAFALIFSTFSKAAIQVLDKHYHLSDNITTIFLLLIQPITVLIIFVGLMLLYFLLPNVKIKKIRYILPGTLFTSFVMTFLSNLVGNYVVYNVERMVDIKMFGSVMIFIIMLWFIFLARILILGAIFNATYQEMSLGKLEGRSGDMIAILKKTLGNDSDLSPSQSIEDSHTD
>NZ_LS483415.1|WP_164552703.1|1049991_1051275_-|3-phosphoshikimate-1-carboxyvinyltransferase
MKLRTNAGPLQGTIQVPGDKSISHRAVILGAVAKGETRVKGLLKGEDVLSTIQAFRNLGVRIEEKDDQLVIEGQGFQGLTAPCQTLNMGNSGTSMRLIAGLLAGQPFSVKMIGDESLSKRPMDRIVYPLKQMGVEISGETDRQFPPLQLQGNRNLQPITYTLPISSAQVKSAILLAALQAKGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVGPQQLTAQEITVPGDISSAAFWLVAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQIVYEDMNKKEQVTSIRVVYSRLKGTIISGGLIPRLIDELPIIALLATQAQGTTCIKDAQELRVKETDRIQVVTDTLNSMGANIKATADGMIIKGLTVLYGANTSTYGDHRIGMMTAIAALLVKQGQVHLDKEEAIMTSYPTFFKDLERLCHD
>NZ_LS483415.1|WP_009880588.1|1049507_1049999_-|shikimate-kinase
MTKVLLGFMGVGKTTVSKHLSMHCKDMDAIIEAKIGMSIAAFFEQHGEIAFRTIENQVLKDLLFANDNSVIVTGGGVVVLQENRQLLRKNHQHNILLVASFETLYQRLKHDKKSQRPLFLKYSKEAFYEFYQQRMVFYEGLSDLVIRVDHRTPEEVANIIEGY
>NZ_LS483415.1|WP_002984109.1|1047848_1049300_-|LCP-family-protein
MTKYPMGGLSHHEELRYFYLLRNLSYLSENEKKEFAFLKSKLEIGRAYAPSKQHYRKSKRQEPYFEDDYYNDYSPNDLLEDDDVNHDSSFVPYGLPIYPKEDRYLNKKTKLTARRPIDAPQPIDEDDAFLTESVARCALPRSQKRKHKKKGCMKWFFNILGLLLMTVLMGLGLMFAKGVFDISTNKANYKPAVSQAFDGQETQDGTNILVLGSDQRVTQGSTDARTDTIMVVNVGNHAKKIKMVSFMRDTLINIPGYSYNDNSYDLKLNSAFNLGEQEDHHGAEYVRRALKHNFDIDIKYYVMVDFETFAEAIDTLFPNGVKIDAKFATVGGVAVDSVEVPDDLRMKNGVVPNQTIEVGEQRMDGRTLLNYARFRKDDEGDFGRTVRQQQVMSAVMSQIKDPTKLFTGSAAIGKIYALTSTNVSFPFVVKNGVSVLGSGKNGVEHVTIPENGDWVDEYDMYGGQALYIDFDKYQKTLAKLGLR
>NZ_LS483415.1|WP_011106727.1|1046411_1047800_-|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MVSPRKGKRIRMLKKNDIIQVAISDLSHEGAGVAKHDGFVFFVDNALPEEVIDMRVLKVNKNSGFGKVEAYHYLSPARNADVNLTYLRTGIADLGHLTYEDQLTFKKKQVQDSLYKIAGISDVTVESTIGMTEPLAYRNKAQVPVRRVNGQLETGFFRKHSHDLIPISDYYIQDKEIDRLINFTRDLLRRFDIKPYDETEQTGLLRNIVVRRGHYSGEMMLVLVTTRPKVFRVDQVIEKIVEAFPAVVSIIQNINDKNTNAIFGKDFKTLYGKDTITDSMLGNNYAISAQSFYQVNTVMAEKLYQTAIAFSDLSKDDIVIDAYSGIGTIGLSFAKTVKAVYGVEVIEAAVRDAQHNAALNGITNAYFVADTAEHAMATWAKDGIKPSVILVDPPRKGLTESFIQASVAMGPQKITYVSCNPATMARDIKRYQELGYKLAKVQPVDLFPQTHHVECVVLLIKE
>NZ_LS483415.1|WP_111705658.1|1045687_1046302_-|nucleoside-phosphorylase
MSATKDSPVYQIPYKGQDICLAQAPVGSAPAAQFMDWLIGYGVKEMISTGTCGVLVPIAENRFLVPVKALRDEGTSYHYVAPSRYIDIDPKMLRLIEKTLLAQGLAYQEVITWSTDGFYRKTKEKVAYRQEEGCSVVEMECSALAAVAQLRGILWGQLLFTADTLADVEVYDQRNWGADSFSFALHLCLEVLNTLEKDGKATDF
>NZ_LS483415.1|WP_002984115.1|1045201_1045603_-|PaaI-family-thioesterase
MSDLTQEMTLNVISIFDNYQIELAEKGHLILSTEVTETALNYYGNAHGGYLFTLCDQVGGLVARTTGVESVTLQANANYLKAGHKGDKLMVEGRLVHGGRTTQVVDVTIHNQTGALLTKTSLTMFVTGRRHNG
>NZ_LS483415.1|WP_002989295.1|1057589_1058849_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIYMDTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGTYIALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKADGRGTIIDTIYEKRINHVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITNIEFILRGYASIIAKLTALGADIQLIED
>NZ_LS483415.1|WP_111705664.1|1059022_1060219_-|methionine-adenosyltransferase
MSERKLFTSESVSEGHPDKIADQISDAILDAILVEDPEAHVAAETCVYTGSVHVFGEISTTAYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSGDIAQGVNEALESREGDTDDLSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLAELRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEATNDQIRQDVIEKVIKAVIPADYLDDDTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNLVAAGLATKAEVQLAYAIGVAQPVSVRVDTFGTSTVPEAVLEAAVRQVFDLRPAGIIQMLDLKRPIYKQTAAYGHMGRTDIDLPWERLNKVDALVEAVKTVL
>NZ_LS483415.1|WP_111705665.1|1060755_1063134_-|leucine-rich-repeat-domain-containing-protein
MKTKKVIILVGLLLSSQLTLIACQSRGNGTYPIKTKQSRKGMTSNKIKPIKKSKKTNKTHKGVAGVDFPTDDGFILTKDSKILSKTDQGIVVDHDGHSHFIFYADLKGSPFEYLIPKGASLAKPAVAQQAASQGTSKVADPHHHYEFNPADIVAEDALGYTVRHDDHFHYILKSSLSGQTQAQAKQVATRLPQTSSPVSTATANGIPGLHFPTSDGFQFNGQGIVGVTKDSILVDHDGHLHPISFADLRQGGWAHVADQYDPAKKADKLTEPKQTQEQANREKEYQEKLAYLAEKLGIDPSTIKRVETQDGKLGLEYPHHDHAHVLMLSDIEIGKDIPDPHAIEHARELEKHKVGMDTLRALGFDEEVILDIVRTHDAPTPFPSNEKDPNKMKEWLATVIKLDLGSRKDPLQRKGLSLLPNLETLGIGFTPIKDISPVLQFKKLKQLLMTKTGVTDYRFLDNMPQLEGIDISQNNLKDISFLSKYKNLTLVAAADNGIEDIRPLGQLPNLKFLVLSNNKISDLSPLASLHQLQELHIDNNQITDLSPVSHKESLTVMDLSRNAAIDLTTLEAPKLDTLMVNETKVARLDFLKNNPSLASLSINRAQLESLDGIEASSVIVRVEAEGNQIKSLVLKDKQGSLTFLDVTGNQLTSLEGVNDFTALDILSVSKNQLTNVNLSEPNKTITNIDISHNQIPLSDLKLNEQHIPEAIAKNFPAVQEGSMVGNGTAEEKAAMATKAKESAQEASESHDYNHNHAYEDEEGHAHEHRDKDDHDHEHEDENEAKDEQNHAD
>NZ_LS483415.1|WP_011017924.1|1063336_1064278_+|bifunctional-biotin--[acetyl-CoA-carboxylase]-synthetase/biotin-operon-repressor
MKTSEKIYQLLSQTDDFVSGEYLADQLSISRTSVWKSIKSLENQGIQIDSLKHKGYRMVQGDILLPKTISQGLGMPVTYTPHSQSTQLDAKQGIEAHNSAPRLYLAPSQEAAKGRLDRQFFSASTGGIYMSMYLKPNVPYADMPPYTMMVASSIVKAISRLTGIDTEIKWVNDIYLGNHKVAGILTEAITSVETGLITDVIIGVGLNFFVTDFPEAIAQKAGSLFTEKPTITRNDLIIDIWKLFLSIPVKDHVKVYKEKSLVLNKQVTFIENSQEKRAIAIDLTDQGHLIVQFDNGDLQTLRSGEISLSSWEN
>NZ_LS483415.1|WP_012560785.1|1064252_1064456_-|DUF3272-domain-containing-protein
MTIRQFLFMAFVCAFETYFFNDLLLSGNYLFALFWGLLLFRDLRRVHTINQLTKTILKAANSPKKKD
>NZ_LS483415.1|WP_002984073.1|1064550_1066221_-|DNA-polymerase-III-subunit-gamma/tau
MYQALYRKYRSQTFDEMVGQSVISTTLKQAVESGKISHAYLFSGPRGTGKTSAAKIFAKAMNCPNQVDGEPCNQCDICRDITNGSLEDVIEIDAASNNGVDEIRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPTENVVFILATTELHKIPATILSRVQRFEFKAIKQKAIREHLAWVLDKEGIAYEVDALNLIARRAEGGMRDALSILDQALSLSPDNQVTIAIAEEITGSISMLALGDYVRYVSQEQATQALAALETIYDSGKSMSRFATDLLTYLRDLLVVKAGGDNQRQSAVFDTNLSLSIDRIFQMITVVTSHLPEIKKGTHPRIYAEMMTIQLAQKEQILSQANLSGELISEIETLKNELAQLKQQLSQLQSRPDSLARSDKTKPKTASYRVDRVTILKIMEETVRNSQQSRQYLDALKNAWNEILDNISAQDRALLMGSEPVLANSENAILAFEAAFNAEQVMSRNNLNDMFGNIMSKAAGFSPNILAVPRTDFQHIRKEFAQQMKSQKDSVQEEQEVALDIPEGFDFLLDKINTIDD
>NZ_LS483415.1|WP_010922414.1|1066220_1066718_-|GAF-domain-containing-protein
MNKSKKIEQYQLMIAQAKELFANESNALANLSNASALLNMTLPNSVFTGFYLFDGQELILGPFQGRVSCVHIKLGKGVCGESAQSRRTIIINDVKQHANYISCDAAAMSEIVVPMVKEGHLIGVLDLDSSLVADYDEVDQEYLEAFVDLFLEKTTFTFNMFGVKN
>NZ_LS483415.1|WP_002989260.1|1066862_1067672_+|PrsW-family-intramembrane-metalloprotease
MKQITQQKWLRYGLFIALVLNGIELELLGLTANNLSFKEAFALILTISLLGIYLIPFAAAIFYLSKKFHMNLNVIIVSCLSGLYISGFLASCGNHLVGQFWSYIIPSKDALKLWGDALTAPIVEEPIKASSAILVITLFPRLTLKEKLVVALLSGMGFQLTEDIRYLIQAKSIDSLVPTAIERISTAVTSHWVHTAIFTIGAYLLLKGSNLFSKQQQIFWLLSPLVLHFIWNSPLTSIPGMTVLLGTLILLIFGDLFQKINTLDDDVLF
>NZ_LS483415.1|WP_002989257.1|1067724_1067988_-|DUF1294-domain-containing-protein
MLLIWLGLLFVWNELVFVIYAFDKRKAIKKKRRISERNLLVITVLFGGFGALLAAKKYHHKTRKWYFVITWYTSILLTLLVTYIFMK
>NZ_LS483415.1|WP_011017929.1|1068067_1068694_-|uridine-kinase
MFKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYKDQSHMSFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKKHTRSNTTFRQDPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQYTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSKIASILGEV

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	NZ_LS483415.1	975276-975305	0	1.0
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	NZ_LS483415.1	1331407-1331436	1	0.967

1. spacer 1.1|779683|30|NZ_LS483415|CRT matches to position: 975276-975305, mismatch: 0, identity: 1.0

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgagctgagtttactcgtagtaatca	Protospacer
******************************

2. spacer 1.1|779683|30|NZ_LS483415|CRT matches to position: 1331407-1331436, mismatch: 1, identity: 0.967

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgtgctgagtttactcgtagtaatca	Protospacer
****** ***********************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448944	Streptococcus phage Javan452, complete genome	36987-37016	0	1.0
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	MK448960	Streptococcus phage Javan492, complete genome	37074-37103	0	1.0
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	MK448762	Streptococcus phage Javan447, complete genome	37207-37236	0	1.0
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	MK448772	Streptococcus phage Javan483, complete genome	37930-37959	0	1.0
NZ_LS483415_1	1.4\|779881\|30\|NZ_LS483415\|CRT,PILER-CR	779881-779910	30	MK448798	Streptococcus phage Javan533, complete genome	8398-8427	0	1.0
NZ_LS483415_1	1.4\|779881\|30\|NZ_LS483415\|CRT,PILER-CR	779881-779910	30	NC_004585	Streptococcus prophage 315.2, complete genome	10896-10925	0	1.0
NZ_LS483415_1	1.4\|779881\|30\|NZ_LS483415\|CRT,PILER-CR	779881-779910	30	MK448955	Streptococcus phage Javan478, complete genome	9992-10021	0	1.0
NZ_LS483415_1	1.4\|779881\|30\|NZ_LS483415\|CRT,PILER-CR	779881-779910	30	MK448966	Streptococcus phage Javan508, complete genome	10751-10780	0	1.0
NZ_LS483415_1	1.4\|779881\|30\|NZ_LS483415\|CRT,PILER-CR	779881-779910	30	KT388093	Streptococcus phage A25, complete genome	5355-5384	0	1.0
NZ_LS483415_1	1.4\|779881\|30\|NZ_LS483415\|CRT,PILER-CR	779881-779910	30	MK448772	Streptococcus phage Javan483, complete genome	10766-10795	0	1.0
NZ_LS483415_1	1.4\|779881\|30\|NZ_LS483415\|CRT,PILER-CR	779881-779910	30	MK448783	Streptococcus phage Javan503, complete genome	8313-8342	0	1.0
NZ_LS483415_1	1.4\|779881\|30\|NZ_LS483415\|CRT,PILER-CR	779881-779910	30	MK448967	Streptococcus phage Javan510, complete genome	8399-8428	0	1.0
NZ_LS483415_1	1.4\|779881\|30\|NZ_LS483415\|CRT,PILER-CR	779881-779910	30	KY349816	Streptococcus phage Str01, complete genome	30558-30587	0	1.0
NZ_LS483415_1	1.4\|779881\|30\|NZ_LS483415\|CRT,PILER-CR	779881-779910	30	NC_004588	Streptococcus prophage 315.5, complete genome	8548-8577	0	1.0
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448960	Streptococcus phage Javan492, complete genome	33511-33540	1	0.967
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448973	Streptococcus phage Javan522, complete genome	34924-34953	1	0.967
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448762	Streptococcus phage Javan447, complete genome	33644-33673	1	0.967
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448775	Streptococcus phage Javan489, complete genome	36329-36358	1	0.967
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448955	Streptococcus phage Javan478, complete genome	36920-36949	1	0.967
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448970	Streptococcus phage Javan516, complete genome	39929-39958	1	0.967
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448795	Streptococcus phage Javan527, complete genome	39953-39982	1	0.967
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448791	Streptococcus phage Javan517, complete genome	33780-33809	1	0.967
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448953	Streptococcus phage Javan474, complete genome	38050-38079	1	0.967
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448945	Streptococcus phage Javan454, complete genome	33883-33912	1	0.967
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448778	Streptococcus phage Javan493, complete genome	34564-34593	1	0.967
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448975	Streptococcus phage Javan526, complete genome	35346-35375	1	0.967
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448782	Streptococcus phage Javan501, complete genome	37704-37733	1	0.967
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	MK448793	Streptococcus phage Javan523, complete genome	38551-38580	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448852	Streptococcus phage Javan140, complete genome	35945-35974	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448771	Streptococcus phage Javan481, complete genome	30334-30363	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448973	Streptococcus phage Javan522, complete genome	36960-36989	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448860	Streptococcus phage Javan172, complete genome	34739-34768	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448779	Streptococcus phage Javan497, complete genome	35211-35240	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448969	Streptococcus phage Javan514, complete genome	29058-29087	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	NC_004585	Streptococcus prophage 315.2, complete genome	36272-36301	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448976	Streptococcus phage Javan528, complete genome	34444-34473	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448966	Streptococcus phage Javan508, complete genome	36127-36156	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448970	Streptococcus phage Javan516, complete genome	41706-41735	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448972	Streptococcus phage Javan520, complete genome	30993-31022	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448795	Streptococcus phage Javan527, complete genome	41727-41756	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448944	Streptococcus phage Javan452, complete genome	38761-38790	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448959	Streptococcus phage Javan488, complete genome	36817-36846	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448945	Streptococcus phage Javan454, complete genome	35660-35689	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448774	Streptococcus phage Javan487, complete genome	29172-29201	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448772	Streptococcus phage Javan483, complete genome	36370-36399	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448766	Streptococcus phage Javan465, complete genome	36350-36379	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448778	Streptococcus phage Javan493, complete genome	36603-36632	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448773	Streptococcus phage Javan485, complete genome	31944-31973	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448797	Streptococcus phage Javan531, complete genome	35319-35348	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448949	Streptococcus phage Javan460, complete genome	37616-37645	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448793	Streptococcus phage Javan523, complete genome	37005-37034	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448957	Streptococcus phage Javan484, complete genome	40784-40813	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448975	Streptococcus phage Javan526, complete genome	37385-37414	1	0.967
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448782	Streptococcus phage Javan501, complete genome	39743-39772	1	0.967
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448952	Streptococcus phage Javan472, complete genome	33911-33940	2	0.933
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448794	Streptococcus phage Javan525, complete genome	33455-33484	2	0.933
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448793	Streptococcus phage Javan523, complete genome	34972-35001	2	0.933
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448765	Streptococcus phage Javan459, complete genome	33453-33482	2	0.933
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448784	Streptococcus phage Javan505, complete genome	35108-35137	2	0.933
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448947	Streptococcus phage Javan458, complete genome	35108-35137	2	0.933
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448965	Streptococcus phage Javan506, complete genome	35477-35506	2	0.933
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448859	Streptococcus phage Javan170, complete genome	36417-36446	2	0.933
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448689	Streptococcus phage Javan163, complete genome	35108-35137	2	0.933
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448974	Streptococcus phage Javan524, complete genome	35108-35137	2	0.933
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448676	Streptococcus phage Javan131, complete genome	38810-38839	2	0.933
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448688	Streptococcus phage Javan161, complete genome	36375-36404	2	0.933
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448789	Streptococcus phage Javan513, complete genome	35107-35136	2	0.933
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448678	Streptococcus phage Javan135, complete genome	33690-33719	2	0.933
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	MK448860	Streptococcus phage Javan172, complete genome	36312-36341	2	0.933
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	MK448969	Streptococcus phage Javan514, complete genome	30615-30644	2	0.933
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	MK448972	Streptococcus phage Javan520, complete genome	32550-32579	2	0.933
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	MK448774	Streptococcus phage Javan487, complete genome	30729-30758	2	0.933
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	MK448773	Streptococcus phage Javan485, complete genome	33501-33530	2	0.933
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	MK448957	Streptococcus phage Javan484, complete genome	42341-42370	2	0.933
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448968	Streptococcus phage Javan512, complete genome	35319-35348	2	0.933
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	NC_009819	Streptococcus phage P9, complete genome	35498-35527	2	0.933
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	NC_004589	Streptococcus prophage 315.6, complete genome	35416-35445	2	0.933
NZ_LS483415_1	1.5\|779947\|30\|NZ_LS483415\|CRT	779947-779976	30	MK448871	Streptococcus phage Javan196, complete genome	32397-32426	2	0.933
NZ_LS483415_1	1.5\|779947\|30\|NZ_LS483415\|CRT	779947-779976	30	MK448795	Streptococcus phage Javan527, complete genome	37952-37981	2	0.933
NZ_LS483415_1	1.5\|779947\|30\|NZ_LS483415\|CRT	779947-779976	30	MK448697	Streptococcus phage Javan185, complete genome	32397-32426	2	0.933
NZ_LS483415_1	1.5\|779947\|30\|NZ_LS483415\|CRT	779947-779976	30	MK448693	Streptococcus phage Javan177, complete genome	32397-32426	2	0.933
NZ_LS483415_1	1.5\|779947\|30\|NZ_LS483415\|CRT	779947-779976	30	MK448696	Streptococcus phage Javan183, complete genome	32397-32426	2	0.933
NZ_LS483415_1	1.5\|779947\|30\|NZ_LS483415\|CRT	779947-779976	30	NC_009819	Streptococcus phage P9, complete genome	31358-31387	2	0.933
NZ_LS483415_1	1.5\|779947\|30\|NZ_LS483415\|CRT	779947-779976	30	MK448868	Streptococcus phage Javan188, complete genome	32398-32427	2	0.933
NZ_LS483415_1	1.5\|779947\|30\|NZ_LS483415\|CRT	779947-779976	30	MK448866	Streptococcus phage Javan184, complete genome	32397-32426	2	0.933
NZ_LS483415_1	1.5\|779947\|30\|NZ_LS483415\|CRT	779947-779976	30	MK448699	Streptococcus phage Javan189, complete genome	32397-32426	2	0.933
NZ_LS483415_1	1.5\|779947\|30\|NZ_LS483415\|CRT	779947-779976	30	MK448867	Streptococcus phage Javan186, complete genome	32397-32426	2	0.933
NZ_LS483415_1	1.5\|779947\|30\|NZ_LS483415\|CRT	779947-779976	30	MK448698	Streptococcus phage Javan187, complete genome	26703-26732	2	0.933
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448796	Streptococcus phage Javan53, complete genome	42329-42358	3	0.9
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448951	Streptococcus phage Javan470, complete genome	33709-33738	3	0.9
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	MK448946	Streptococcus phage Javan456, complete genome	41632-41661	3	0.9
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	MK448973	Streptococcus phage Javan522, complete genome	38517-38546	3	0.9
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	NC_004585	Streptococcus prophage 315.2, complete genome	37832-37861	3	0.9
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	MK448966	Streptococcus phage Javan508, complete genome	37687-37716	3	0.9
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	MK448795	Streptococcus phage Javan527, complete genome	43287-43316	3	0.9
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	NC_004584	Streptococcus prophage 315.1, complete genome	36623-36652	3	0.9
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	MK448778	Streptococcus phage Javan493, complete genome	38160-38189	3	0.9
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	MK448978	Streptococcus phage Javan532, complete genome	36517-36546	3	0.9
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	MK448785	Streptococcus phage Javan507, complete genome	36518-36547	3	0.9
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	MK448950	Streptococcus phage Javan464, complete genome	37544-37573	3	0.9
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	MK448975	Streptococcus phage Javan526, complete genome	38942-38971	3	0.9
NZ_LS483415_1	1.2\|779749\|30\|NZ_LS483415\|CRT,PILER-CR	779749-779778	30	MK448782	Streptococcus phage Javan501, complete genome	41301-41330	3	0.9
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448675	Streptococcus phage Javan129, complete genome	38860-38889	3	0.9
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448859	Streptococcus phage Javan170, complete genome	38180-38209	3	0.9
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448850	Streptococcus phage Javan132, complete genome	37960-37989	3	0.9
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448680	Streptococcus phage Javan139, complete genome	33197-33226	3	0.9
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448676	Streptococcus phage Javan131, complete genome	40857-40886	3	0.9
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448688	Streptococcus phage Javan161, complete genome	38138-38167	3	0.9
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448955	Streptococcus phage Javan478, complete genome	38697-38726	3	0.9
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448854	Streptococcus phage Javan146, complete genome	38516-38545	3	0.9
NZ_LS483415_1	1.4\|779881\|30\|NZ_LS483415\|CRT,PILER-CR	779881-779910	30	JX409895	Streptococcus phage JX01, complete genome	6764-6793	3	0.9
NZ_LS483415_1	1.4\|779881\|30\|NZ_LS483415\|CRT,PILER-CR	779881-779910	30	MK448858	Streptococcus phage Javan166, complete genome	10367-10396	3	0.9
NZ_LS483415_1	1.5\|779947\|30\|NZ_LS483415\|CRT	779947-779976	30	MK448763	Streptococcus phage Javan451, complete genome	26918-26947	3	0.9
NZ_LS483415_1	1.5\|779947\|30\|NZ_LS483415\|CRT	779947-779976	30	MK448941	Streptococcus phage Javan446, complete genome	34170-34199	3	0.9
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448679	Streptococcus phage Javan137, complete genome	33831-33860	4	0.867
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448690	Streptococcus phage Javan169, complete genome	38514-38543	4	0.867
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448682	Streptococcus phage Javan143, complete genome	35819-35848	4	0.867
NZ_LS483415_1	1.4\|779881\|30\|NZ_LS483415\|CRT,PILER-CR	779881-779910	30	MK448975	Streptococcus phage Javan526, complete genome	9927-9956	4	0.867
NZ_LS483415_1	1.4\|779881\|30\|NZ_LS483415\|CRT,PILER-CR	779881-779910	30	MK448782	Streptococcus phage Javan501, complete genome	10266-10295	4	0.867
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448701	Streptococcus phage Javan197, complete genome	32416-32445	5	0.833
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448869	Streptococcus phage Javan190, complete genome	32670-32699	5	0.833
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448864	Streptococcus phage Javan180, complete genome	26457-26486	5	0.833
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448694	Streptococcus phage Javan179, complete genome	36462-36491	5	0.833
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	MK448870	Streptococcus phage Javan192, complete genome	32670-32699	5	0.833
NZ_LS483415_1	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	MK448845	Streptococcus phage Javan118, complete genome	30812-30841	6	0.8
NZ_LS483415_1	1.4\|779881\|30\|NZ_LS483415\|CRT,PILER-CR	779881-779910	30	MN830258	Lactobacillus phage JNU_P9, complete genome	14978-15007	8	0.733
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	NZ_CP033508	Mesorhizobium jarvisii strain ATCC 700743 plasmid pMJ700743a, complete sequence	152078-152107	9	0.7
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	NZ_CP033369	Mesorhizobium loti strain SU343 plasmid pMLSU343a, complete sequence	152078-152107	9	0.7
NZ_LS483415_1	1.3\|779815\|30\|NZ_LS483415\|CRT,PILER-CR	779815-779844	30	NZ_CP016080	Mesorhizobium loti NZP2037 plasmid pML2037, complete sequence	380602-380631	9	0.7

1. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 0, identity: 1.0

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgagctgagtttactcgtagtaatca	Protospacer
******************************

2. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to MK448960 (Streptococcus phage Javan492, complete genome) position: , mismatch: 0, identity: 1.0

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaagaatgctccagtccg	Protospacer
******************************

3. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to MK448762 (Streptococcus phage Javan447, complete genome) position: , mismatch: 0, identity: 1.0

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaagaatgctccagtccg	Protospacer
******************************

4. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to MK448772 (Streptococcus phage Javan483, complete genome) position: , mismatch: 0, identity: 1.0

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaagaatgctccagtccg	Protospacer
******************************

5. spacer 1.4|779881|30|NZ_LS483415|CRT,PILER-CR matches to MK448798 (Streptococcus phage Javan533, complete genome) position: , mismatch: 0, identity: 1.0

cagcttggatttaatagcagaccatgtttt	CRISPR spacer
cagcttggatttaatagcagaccatgtttt	Protospacer
******************************

6. spacer 1.4|779881|30|NZ_LS483415|CRT,PILER-CR matches to NC_004585 (Streptococcus prophage 315.2, complete genome) position: , mismatch: 0, identity: 1.0

cagcttggatttaatagcagaccatgtttt	CRISPR spacer
cagcttggatttaatagcagaccatgtttt	Protospacer
******************************

7. spacer 1.4|779881|30|NZ_LS483415|CRT,PILER-CR matches to MK448955 (Streptococcus phage Javan478, complete genome) position: , mismatch: 0, identity: 1.0

cagcttggatttaatagcagaccatgtttt	CRISPR spacer
cagcttggatttaatagcagaccatgtttt	Protospacer
******************************

8. spacer 1.4|779881|30|NZ_LS483415|CRT,PILER-CR matches to MK448966 (Streptococcus phage Javan508, complete genome) position: , mismatch: 0, identity: 1.0

cagcttggatttaatagcagaccatgtttt	CRISPR spacer
cagcttggatttaatagcagaccatgtttt	Protospacer
******************************

9. spacer 1.4|779881|30|NZ_LS483415|CRT,PILER-CR matches to KT388093 (Streptococcus phage A25, complete genome) position: , mismatch: 0, identity: 1.0

cagcttggatttaatagcagaccatgtttt	CRISPR spacer
cagcttggatttaatagcagaccatgtttt	Protospacer
******************************

10. spacer 1.4|779881|30|NZ_LS483415|CRT,PILER-CR matches to MK448772 (Streptococcus phage Javan483, complete genome) position: , mismatch: 0, identity: 1.0

cagcttggatttaatagcagaccatgtttt	CRISPR spacer
cagcttggatttaatagcagaccatgtttt	Protospacer
******************************

11. spacer 1.4|779881|30|NZ_LS483415|CRT,PILER-CR matches to MK448783 (Streptococcus phage Javan503, complete genome) position: , mismatch: 0, identity: 1.0

cagcttggatttaatagcagaccatgtttt	CRISPR spacer
cagcttggatttaatagcagaccatgtttt	Protospacer
******************************

12. spacer 1.4|779881|30|NZ_LS483415|CRT,PILER-CR matches to MK448967 (Streptococcus phage Javan510, complete genome) position: , mismatch: 0, identity: 1.0

cagcttggatttaatagcagaccatgtttt	CRISPR spacer
cagcttggatttaatagcagaccatgtttt	Protospacer
******************************

13. spacer 1.4|779881|30|NZ_LS483415|CRT,PILER-CR matches to KY349816 (Streptococcus phage Str01, complete genome) position: , mismatch: 0, identity: 1.0

cagcttggatttaatagcagaccatgtttt	CRISPR spacer
cagcttggatttaatagcagaccatgtttt	Protospacer
******************************

14. spacer 1.4|779881|30|NZ_LS483415|CRT,PILER-CR matches to NC_004588 (Streptococcus prophage 315.5, complete genome) position: , mismatch: 0, identity: 1.0

cagcttggatttaatagcagaccatgtttt	CRISPR spacer
cagcttggatttaatagcagaccatgtttt	Protospacer
******************************

15. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448960 (Streptococcus phage Javan492, complete genome) position: , mismatch: 1, identity: 0.967

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgtgctgagtttactcgtagtaatca	Protospacer
****** ***********************

16. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 1, identity: 0.967

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgtgctgagtttactcgtagtaatca	Protospacer
****** ***********************

17. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448762 (Streptococcus phage Javan447, complete genome) position: , mismatch: 1, identity: 0.967

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgtgctgagtttactcgtagtaatca	Protospacer
****** ***********************

18. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448775 (Streptococcus phage Javan489, complete genome) position: , mismatch: 1, identity: 0.967

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgagctgagtttactcatagtaatca	Protospacer
********************.*********

19. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448955 (Streptococcus phage Javan478, complete genome) position: , mismatch: 1, identity: 0.967

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgagctgagtttactcatagtaatca	Protospacer
********************.*********

20. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448970 (Streptococcus phage Javan516, complete genome) position: , mismatch: 1, identity: 0.967

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgagctgagtttactcatagtaatca	Protospacer
********************.*********

21. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 1, identity: 0.967

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgagctgagtttactcatagtaatca	Protospacer
********************.*********

22. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448791 (Streptococcus phage Javan517, complete genome) position: , mismatch: 1, identity: 0.967

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgagctgagtttactcatagtaatca	Protospacer
********************.*********

23. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448953 (Streptococcus phage Javan474, complete genome) position: , mismatch: 1, identity: 0.967

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgagctgagtttactcatagtaatca	Protospacer
********************.*********

24. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448945 (Streptococcus phage Javan454, complete genome) position: , mismatch: 1, identity: 0.967

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgagctgagtttactcatagtaatca	Protospacer
********************.*********

25. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 1, identity: 0.967

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgtgctgagtttactcgtagtaatca	Protospacer
****** ***********************

26. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448975 (Streptococcus phage Javan526, complete genome) position: , mismatch: 1, identity: 0.967

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgtgctgagtttactcgtagtaatca	Protospacer
****** ***********************

27. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448782 (Streptococcus phage Javan501, complete genome) position: , mismatch: 1, identity: 0.967

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgtgctgagtttactcgtagtaatca	Protospacer
****** ***********************

28. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 1, identity: 0.967

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaaaaatgctccagtccg	Protospacer
***************.**************

29. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448852 (Streptococcus phage Javan140, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

30. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

31. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

32. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448860 (Streptococcus phage Javan172, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

33. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448779 (Streptococcus phage Javan497, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

34. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

35. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to NC_004585 (Streptococcus prophage 315.2, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

36. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448976 (Streptococcus phage Javan528, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

37. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448966 (Streptococcus phage Javan508, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

38. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448970 (Streptococcus phage Javan516, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

39. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

40. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

41. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

42. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448959 (Streptococcus phage Javan488, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

43. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448945 (Streptococcus phage Javan454, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

44. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

45. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448772 (Streptococcus phage Javan483, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

46. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448766 (Streptococcus phage Javan465, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

47. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

48. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

49. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448797 (Streptococcus phage Javan531, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

50. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448949 (Streptococcus phage Javan460, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

51. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

52. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448957 (Streptococcus phage Javan484, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

53. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448975 (Streptococcus phage Javan526, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

54. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448782 (Streptococcus phage Javan501, complete genome) position: , mismatch: 1, identity: 0.967

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataaatgtc	Protospacer
*****************************.

55. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448952 (Streptococcus phage Javan472, complete genome) position: , mismatch: 2, identity: 0.933

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
tttacgtgctgagtttactcgtagtaatca	Protospacer
.***** ***********************

56. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448794 (Streptococcus phage Javan525, complete genome) position: , mismatch: 2, identity: 0.933

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
tttacgtgctgagtttactcgtagtaatca	Protospacer
.***** ***********************

57. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 2, identity: 0.933

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
tttacgtgctgagtttactcgtagtaatca	Protospacer
.***** ***********************

58. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448765 (Streptococcus phage Javan459, complete genome) position: , mismatch: 2, identity: 0.933

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
tttacgtgctgagtttactcgtagtaatca	Protospacer
.***** ***********************

59. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448784 (Streptococcus phage Javan505, complete genome) position: , mismatch: 2, identity: 0.933

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgagctgagtttactcgtagccatca	Protospacer
************************. ****

60. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448947 (Streptococcus phage Javan458, complete genome) position: , mismatch: 2, identity: 0.933

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgagctgagtttactcgtagccatca	Protospacer
************************. ****

61. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448965 (Streptococcus phage Javan506, complete genome) position: , mismatch: 2, identity: 0.933

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgagctgagtttactcgtagccatca	Protospacer
************************. ****

62. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448859 (Streptococcus phage Javan170, complete genome) position: , mismatch: 2, identity: 0.933

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgagctgagtttactcgtagccatca	Protospacer
************************. ****

63. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448689 (Streptococcus phage Javan163, complete genome) position: , mismatch: 2, identity: 0.933

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgagctgagtttactcgtagccatca	Protospacer
************************. ****

64. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448974 (Streptococcus phage Javan524, complete genome) position: , mismatch: 2, identity: 0.933

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgagctgagtttactcgtagccatca	Protospacer
************************. ****

65. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448676 (Streptococcus phage Javan131, complete genome) position: , mismatch: 2, identity: 0.933

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgagctgagtttactcgtagccatca	Protospacer
************************. ****

66. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448688 (Streptococcus phage Javan161, complete genome) position: , mismatch: 2, identity: 0.933

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgagctgagtttactcgtagccatca	Protospacer
************************. ****

67. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448789 (Streptococcus phage Javan513, complete genome) position: , mismatch: 2, identity: 0.933

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgagctgagtttactcgtagccatca	Protospacer
************************. ****

68. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448678 (Streptococcus phage Javan135, complete genome) position: , mismatch: 2, identity: 0.933

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgagctgagtttactcgtagccatca	Protospacer
************************. ****

69. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to MK448860 (Streptococcus phage Javan172, complete genome) position: , mismatch: 2, identity: 0.933

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaaaaacgctccagtccg	Protospacer
***************.**.***********

70. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 2, identity: 0.933

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaaaaatgctccagtctg	Protospacer
***************.************.*

71. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 2, identity: 0.933

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaaaaatgctccagtctg	Protospacer
***************.************.*

72. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 2, identity: 0.933

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaaaaatgctccagtctg	Protospacer
***************.************.*

73. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 2, identity: 0.933

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaaaaatgctccagtctg	Protospacer
***************.************.*

74. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to MK448957 (Streptococcus phage Javan484, complete genome) position: , mismatch: 2, identity: 0.933

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaaaaatgctccagtctg	Protospacer
***************.************.*

75. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448968 (Streptococcus phage Javan512, complete genome) position: , mismatch: 2, identity: 0.933

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataagtgtc	Protospacer
*************************.***.

76. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to NC_009819 (Streptococcus phage P9, complete genome) position: , mismatch: 2, identity: 0.933

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagttcaagcatgcctttataaatgtc	Protospacer
******.**********************.

77. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to NC_004589 (Streptococcus prophage 315.6, complete genome) position: , mismatch: 2, identity: 0.933

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttataagtgtc	Protospacer
*************************.***.

78. spacer 1.5|779947|30|NZ_LS483415|CRT matches to MK448871 (Streptococcus phage Javan196, complete genome) position: , mismatch: 2, identity: 0.933

gcacgagtttaactcccttattattagctt	CRISPR spacer
gtaccagtttaactcccttattattagctt	Protospacer
*.** *************************

79. spacer 1.5|779947|30|NZ_LS483415|CRT matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 2, identity: 0.933

gcacgagtttaactcccttattattagctt	CRISPR spacer
gtaccagtttaactcccttattattagctt	Protospacer
*.** *************************

80. spacer 1.5|779947|30|NZ_LS483415|CRT matches to MK448697 (Streptococcus phage Javan185, complete genome) position: , mismatch: 2, identity: 0.933

gcacgagtttaactcccttattattagctt	CRISPR spacer
gtaccagtttaactcccttattattagctt	Protospacer
*.** *************************

81. spacer 1.5|779947|30|NZ_LS483415|CRT matches to MK448693 (Streptococcus phage Javan177, complete genome) position: , mismatch: 2, identity: 0.933

gcacgagtttaactcccttattattagctt	CRISPR spacer
gtaccagtttaactcccttattattagctt	Protospacer
*.** *************************

82. spacer 1.5|779947|30|NZ_LS483415|CRT matches to MK448696 (Streptococcus phage Javan183, complete genome) position: , mismatch: 2, identity: 0.933

gcacgagtttaactcccttattattagctt	CRISPR spacer
gtaccagtttaactcccttattattagctt	Protospacer
*.** *************************

83. spacer 1.5|779947|30|NZ_LS483415|CRT matches to NC_009819 (Streptococcus phage P9, complete genome) position: , mismatch: 2, identity: 0.933

gcacgagtttaactcccttattattagctt	CRISPR spacer
gtaccagtttaactcccttattattagctt	Protospacer
*.** *************************

84. spacer 1.5|779947|30|NZ_LS483415|CRT matches to MK448868 (Streptococcus phage Javan188, complete genome) position: , mismatch: 2, identity: 0.933

gcacgagtttaactcccttattattagctt	CRISPR spacer
gtaccagtttaactcccttattattagctt	Protospacer
*.** *************************

85. spacer 1.5|779947|30|NZ_LS483415|CRT matches to MK448866 (Streptococcus phage Javan184, complete genome) position: , mismatch: 2, identity: 0.933

gcacgagtttaactcccttattattagctt	CRISPR spacer
gtaccagtttaactcccttattattagctt	Protospacer
*.** *************************

86. spacer 1.5|779947|30|NZ_LS483415|CRT matches to MK448699 (Streptococcus phage Javan189, complete genome) position: , mismatch: 2, identity: 0.933

gcacgagtttaactcccttattattagctt	CRISPR spacer
gtaccagtttaactcccttattattagctt	Protospacer
*.** *************************

87. spacer 1.5|779947|30|NZ_LS483415|CRT matches to MK448867 (Streptococcus phage Javan186, complete genome) position: , mismatch: 2, identity: 0.933

gcacgagtttaactcccttattattagctt	CRISPR spacer
gtaccagtttaactcccttattattagctt	Protospacer
*.** *************************

88. spacer 1.5|779947|30|NZ_LS483415|CRT matches to MK448698 (Streptococcus phage Javan187, complete genome) position: , mismatch: 2, identity: 0.933

gcacgagtttaactcccttattattagctt	CRISPR spacer
gtaccagtttaactcccttattattagctt	Protospacer
*.** *************************

89. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448796 (Streptococcus phage Javan53, complete genome) position: , mismatch: 3, identity: 0.9

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
attacgtgctgagtttactcgtagttatca	Protospacer
 ***** ****************** ****

90. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448951 (Streptococcus phage Javan470, complete genome) position: , mismatch: 3, identity: 0.9

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttgcgtgctgagtttactcgtagtaatga	Protospacer
***.** ********************* *

91. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to MK448946 (Streptococcus phage Javan456, complete genome) position: , mismatch: 3, identity: 0.9

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaagaatgctcctgctcg	Protospacer
************************ *..**

92. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 3, identity: 0.9

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaaaaatgctcccgtcag	Protospacer
***************.******** *** *

93. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to NC_004585 (Streptococcus prophage 315.2, complete genome) position: , mismatch: 3, identity: 0.9

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaaaaatgctcccgtcag	Protospacer
***************.******** *** *

94. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to MK448966 (Streptococcus phage Javan508, complete genome) position: , mismatch: 3, identity: 0.9

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaaaaatgctcccgtcag	Protospacer
***************.******** *** *

95. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 3, identity: 0.9

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaaaaatgctcccgtcag	Protospacer
***************.******** *** *

96. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to NC_004584 (Streptococcus prophage 315.1, complete genome) position: , mismatch: 3, identity: 0.9

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaaaaatgctcccgtcag	Protospacer
***************.******** *** *

97. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 3, identity: 0.9

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaaaaatgctcccgtcag	Protospacer
***************.******** *** *

98. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to MK448978 (Streptococcus phage Javan532, complete genome) position: , mismatch: 3, identity: 0.9

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaaaaatgctcccgtcag	Protospacer
***************.******** *** *

99. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to MK448785 (Streptococcus phage Javan507, complete genome) position: , mismatch: 3, identity: 0.9

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaaaaatgctcccgtcag	Protospacer
***************.******** *** *

100. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 3, identity: 0.9

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaaaaatgctcccgtcag	Protospacer
***************.******** *** *

101. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to MK448975 (Streptococcus phage Javan526, complete genome) position: , mismatch: 3, identity: 0.9

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaaaaatgctcccgtcag	Protospacer
***************.******** *** *

102. spacer 1.2|779749|30|NZ_LS483415|CRT,PILER-CR matches to MK448782 (Streptococcus phage Javan501, complete genome) position: , mismatch: 3, identity: 0.9

cactgattggacaaagaatgctccagtccg	CRISPR spacer
cactgattggacaaaaaatgctcccgtcag	Protospacer
***************.******** *** *

103. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448675 (Streptococcus phage Javan129, complete genome) position: , mismatch: 3, identity: 0.9

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
aataagctcaagcatgcctttataaatgtc	Protospacer
.** *************************.

104. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448859 (Streptococcus phage Javan170, complete genome) position: , mismatch: 3, identity: 0.9

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
aataagctcaagcatgcctttataaatgtc	Protospacer
.** *************************.

105. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448850 (Streptococcus phage Javan132, complete genome) position: , mismatch: 3, identity: 0.9

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
aataagctcaagcatgcctttataaatgtc	Protospacer
.** *************************.

106. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448680 (Streptococcus phage Javan139, complete genome) position: , mismatch: 3, identity: 0.9

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
aataagctcaagcatgcctttataaatgtc	Protospacer
.** *************************.

107. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448676 (Streptococcus phage Javan131, complete genome) position: , mismatch: 3, identity: 0.9

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
aataagctcaagcatgcctttataaatgtc	Protospacer
.** *************************.

108. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448688 (Streptococcus phage Javan161, complete genome) position: , mismatch: 3, identity: 0.9

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
aataagctcaagcatgcctttataaatgtc	Protospacer
.** *************************.

109. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448955 (Streptococcus phage Javan478, complete genome) position: , mismatch: 3, identity: 0.9

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttgtaaatatc	Protospacer
*********************.*****.*.

110. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448854 (Streptococcus phage Javan146, complete genome) position: , mismatch: 3, identity: 0.9

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctcaagcatgcctttgtaaatatc	Protospacer
*********************.*****.*.

111. spacer 1.4|779881|30|NZ_LS483415|CRT,PILER-CR matches to JX409895 (Streptococcus phage JX01, complete genome) position: , mismatch: 3, identity: 0.9

cagcttggatttaatagcagaccatgtttt	CRISPR spacer
caatttggatttgatagcagaccatgtttt	Protospacer
**..********.*****************

112. spacer 1.4|779881|30|NZ_LS483415|CRT,PILER-CR matches to MK448858 (Streptococcus phage Javan166, complete genome) position: , mismatch: 3, identity: 0.9

cagcttggatttaatagcagaccatgtttt	CRISPR spacer
caatttggatttgatagcagaccatgtttt	Protospacer
**..********.*****************

113. spacer 1.5|779947|30|NZ_LS483415|CRT matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 3, identity: 0.9

gcacgagtttaactcccttattattagctt	CRISPR spacer
gtaccagtttaactcccttattattagcct	Protospacer
*.** ***********************.*

114. spacer 1.5|779947|30|NZ_LS483415|CRT matches to MK448941 (Streptococcus phage Javan446, complete genome) position: , mismatch: 3, identity: 0.9

gcacgagtttaactcccttattattagctt	CRISPR spacer
gtaccagtttaactcccttattattagcct	Protospacer
*.** ***********************.*

115. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448679 (Streptococcus phage Javan137, complete genome) position: , mismatch: 4, identity: 0.867

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctctaacatgcctttataaatatc	Protospacer
********* *.***************.*.

116. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448690 (Streptococcus phage Javan169, complete genome) position: , mismatch: 4, identity: 0.867

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctctaacatgcctttataaatatc	Protospacer
********* *.***************.*.

117. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448682 (Streptococcus phage Javan143, complete genome) position: , mismatch: 4, identity: 0.867

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattagctctaacatgcctttataaatatc	Protospacer
********* *.***************.*.

118. spacer 1.4|779881|30|NZ_LS483415|CRT,PILER-CR matches to MK448975 (Streptococcus phage Javan526, complete genome) position: , mismatch: 4, identity: 0.867

cagcttggatttaatagcagaccatgtttt	CRISPR spacer
caatttggatttgatagcagaccatgttgt	Protospacer
**..********.*************** *

119. spacer 1.4|779881|30|NZ_LS483415|CRT,PILER-CR matches to MK448782 (Streptococcus phage Javan501, complete genome) position: , mismatch: 4, identity: 0.867

cagcttggatttaatagcagaccatgtttt	CRISPR spacer
caatttggatttgatagcagaccatgttgt	Protospacer
**..********.*************** *

120. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448701 (Streptococcus phage Javan197, complete genome) position: , mismatch: 5, identity: 0.833

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
aataagctcaagcatgcctttatagatatc	Protospacer
.** ********************.**.*.

121. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448869 (Streptococcus phage Javan190, complete genome) position: , mismatch: 5, identity: 0.833

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
aataagctcaagcatgcctttatagatatc	Protospacer
.** ********************.**.*.

122. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448864 (Streptococcus phage Javan180, complete genome) position: , mismatch: 5, identity: 0.833

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
aataagctcaagcatgcctttatagatatc	Protospacer
.** ********************.**.*.

123. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448694 (Streptococcus phage Javan179, complete genome) position: , mismatch: 5, identity: 0.833

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
aataagctcaagcatgcctttgtaaatatc	Protospacer
.** *****************.*****.*.

124. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to MK448870 (Streptococcus phage Javan192, complete genome) position: , mismatch: 5, identity: 0.833

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
aataagctcaagcatgcctttatagatatc	Protospacer
.** ********************.**.*.

125. spacer 1.1|779683|30|NZ_LS483415|CRT matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 6, identity: 0.8

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgtgctgagtttactcgctcccatca	Protospacer
****** **************.  . ****

126. spacer 1.4|779881|30|NZ_LS483415|CRT,PILER-CR matches to MN830258 (Lactobacillus phage JNU_P9, complete genome) position: , mismatch: 8, identity: 0.733

cagcttggatttaatagcagaccatgtttt	CRISPR spacer
taaagccgatttaatatcagaccatgcttt	Protospacer
.*.  . ********* *********.***

127. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to NZ_CP033508 (Mesorhizobium jarvisii strain ATCC 700743 plasmid pMJ700743a, complete sequence) position: , mismatch: 9, identity: 0.7

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattacctcaagcatgcctttccggttcaa	Protospacer
***** *************** ... *

128. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to NZ_CP033369 (Mesorhizobium loti strain SU343 plasmid pMLSU343a, complete sequence) position: , mismatch: 9, identity: 0.7

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattacctcaagcatgcctttccggttcaa	Protospacer
***** *************** ... *

129. spacer 1.3|779815|30|NZ_LS483415|CRT,PILER-CR matches to NZ_CP016080 (Mesorhizobium loti NZP2037 plasmid pML2037, complete sequence) position: , mismatch: 9, identity: 0.7

gattagctcaagcatgcctttataaatgtt	CRISPR spacer
gattacctcaagcatgcctttccggttcaa	Protospacer
***** *************** ... *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

37963 : 50350

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111705409.1\|37963_41689_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	6.0e-40	27.0
WP_111705410.1\|41922_43377_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	6.3e-54	32.7
WP_111705411.1\|43404_44427_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	4.0e-63	41.7
WP_002986700.1\|44594_45149_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.4e-25	36.1
WP_111705412.1\|45332_46880_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	5.7e-45	52.4
WP_002987712.1\|46937_48062_-	SH3 domain-containing protein	F8HGP2	Streptococcus_phage	7.7e-07	28.6
WP_111705413.1\|48314_49580_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_111705414.1\|49858_50350_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.4e-18	42.3

DBSCAN-SWA_2

335493 : 391889

Streptococcus_phage(33.33%)

bacteriocin,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111705463.1\|335493_336084_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	7.5e-54	55.2
WP_002985847.1\|336578_336854_+	YlbG family protein	NA	NA	NA	NA
WP_010921930.1\|337102_337738_+	dTMP kinase	M1PSC7	Streptococcus_phage	1.2e-65	63.4
WP_111705464.1\|337755_338631_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.0e-55	41.4
WP_011017422.1\|338649_338889_+	hypothetical protein	NA	NA	NA	NA
WP_002985838.1\|339293_339617_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.3e-28	59.4
WP_111705465.1\|339621_340485_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	3.6e-113	73.6
WP_002985833.1\|340511_340904_+	hypothetical protein	NA	NA	NA	NA
WP_002990900.1\|340950_341580_-	copper homeostasis protein CutC	NA	NA	NA	NA
WP_002990897.1\|341879_342236_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.1e-39	65.0
WP_111705466.1\|342309_343137_-	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	8.4e-128	79.1
WP_172453933.1\|343370_344552_+	L-lactate oxidase	NA	NA	NA	NA
WP_111705468.1\|344817_349761_+\|protease	CXC chemokine-degrading serine protease SpyCEP	NA	NA	NA	NA
WP_002985820.1\|350530_351238_+	DUF1275 domain-containing protein	NA	NA	NA	NA
WP_011184224.1\|351477_353478_+\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	4.6e-87	35.1
WP_032460815.1\|353972_354986_+	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	4.2e-97	53.0
WP_002990870.1\|354989_355478_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	R4JF54	Bacillus_phage	1.3e-11	37.5
WP_111705469.1\|355444_357625_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	1.4e-169	43.1
WP_111705470.1\|357830_358583_-	ADP-ribosyltransferase	NA	NA	NA	NA
WP_011017434.1\|359040_359391_+	hypothetical protein	NA	NA	NA	NA
WP_011017435.1\|359805_360057_+	hypothetical protein	NA	NA	NA	NA
WP_111705471.1\|360151_360652_-	hypothetical protein	NA	NA	NA	NA
WP_002990844.1\|361012_361249_+	DUF2829 domain-containing protein	NA	NA	NA	NA
WP_111705472.1\|361241_361940_+	3-oxoacyl-ACP reductase	A0A0N9R355	Chrysochromulina_ericina_virus	3.5e-10	25.2
WP_111705473.1\|362015_362975_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_002993065.1\|363307_364645_+	MFS transporter	NA	NA	NA	NA
WP_111705474.1\|364818_366201_+	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L4K9	Tupanvirus	2.2e-32	36.4
WP_111701830.1\|366231_366786_+	NUDIX hydrolase	NA	NA	NA	NA
WP_002990826.1\|366785_367037_+	hypothetical protein	NA	NA	NA	NA
WP_011889104.1\|367056_367752_+	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_111705475.1\|367902_368244_+	hypothetical protein	NA	NA	NA	NA
WP_011184242.1\|368340_368988_-	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_111705476.1\|369133_370066_+	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002985780.1\|370129_370855_+	metal ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.4e-17	32.6
WP_002990814.1\|370855_371710_+	metal ABC transporter permease	NA	NA	NA	NA
WP_111705477.1\|371856_372663_-	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.5e-20	36.6
WP_111705478.1\|372879_375285_+	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	3.8e-88	51.7
WP_010921962.1\|375354_375708_-	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_002990800.1\|375951_376377_+	50S ribosomal protein L11	NA	NA	NA	NA
WP_002985768.1\|376482_377172_+	50S ribosomal protein L1	NA	NA	NA	NA
WP_002985765.1\|377493_378222_+	UMP kinase	NA	NA	NA	NA
WP_014635328.1\|378250_378808_+	ribosome recycling factor	NA	NA	NA	NA
WP_011889099.1\|378916_379774_+	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_002990794.1\|379846_380356_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_002985757.1\|380352_380568_+	YozE family protein	NA	NA	NA	NA
WP_111705479.1\|380723_381905_+	LysM peptidoglycan-binding domain-containing protein	A0A0E3XB61	Gordonia_phage	2.1e-15	39.6
WP_111705480.1\|382219_383992_+	oleate hydratase	NA	NA	NA	NA
WP_111705481.1\|384150_385203_+	PhoH family protein	W8D063	Erwinia_phage	1.2e-46	50.0
WP_111705482.1\|385248_385824_+	uracil-DNA glycosylase family protein	NA	NA	NA	NA
WP_002985748.1\|385982_386480_+	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_002985746.1\|386460_386868_+	diacylglycerol kinase	NA	NA	NA	NA
WP_111705483.1\|386987_387884_+	GTPase Era	NA	NA	NA	NA
WP_111705484.1\|387904_388381_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_111705486.1\|389560_389743_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_002992018.1\|390960_391188_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_111705487.1\|391200_391401_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_111701846.1\|391694_391889_+\|bacteriocin	bacteriocin	NA	NA	NA	NA

DBSCAN-SWA_3

609821 : 620424

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011889006.1\|609821_612032_-	LTA synthase family protein	W6LM83	Streptococcus_phage	6.5e-268	68.9
WP_002985142.1\|612139_613303_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	3.4e-143	65.1
WP_002985140.1\|613299_613986_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.0e-88	68.9
WP_002992640.1\|614079_615246_+	chorismate synthase	A0A291AU41	Pandoravirus	5.8e-34	32.8
WP_111705549.1\|615306_615648_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	3.8e-18	40.2
WP_111705550.1\|615868_617221_+	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	3.1e-31	24.2
WP_111705551.1\|617308_618577_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_011889001.1\|618606_619047_-	hypothetical protein	NA	NA	NA	NA
WP_011184383.1\|619281_620424_+	cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	1.4e-24	27.3

DBSCAN-SWA_4

972782 : 1040671

Streptococcus_phage(40.35%)

transposase,portal,tail,holin,terminase,integrase,head

attL 1007307:1007322|attR 1011495:1011510

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003058873.1\|972782_973010_-\|holin	phage holin	A7J2B3	Streptococcus_phage	2.0e-31	100.0
WP_002987582.1\|973006_973282_-	hypothetical protein	A7J2B2	Streptococcus_phage	2.6e-41	100.0
WP_047235258.1\|973291_973909_-	DUF1366 domain-containing protein	Q938J7	Temperate_phage	1.4e-79	89.3
WP_002987333.1\|973911_974073_-	hypothetical protein	NA	NA	NA	NA
WP_002987337.1\|974086_975997_-	gp58-like family protein	Q938J9	Temperate_phage	6.0e-121	71.3
WP_111705642.1\|976009_977017_-	hyaluronoglucosaminidase	A7J2A8	Streptococcus_phage	2.6e-139	72.2
WP_111705643.1\|977013_979050_-\|tail	phage tail protein	A3F656	Streptococcus_phage	0.0e+00	84.1
WP_002984411.1\|979046_979826_-\|tail	phage tail family protein	A3F655	Streptococcus_phage	1.9e-68	55.5
WP_047235256.1\|979857_983124_-	tape measure protein	U6E979	Streptococcus_phage	1.6e-04	30.4
WP_002984407.1\|983138_983468_-	hypothetical protein	A0A1P8BLR3	Lactococcus_phage	2.0e-11	41.5
WP_002984405.1\|983509_983869_-	hypothetical protein	D7RWD6	Brochothrix_phage	4.3e-20	44.5
WP_111705877.1\|983914_984523_-\|tail	phage major tail protein, TP901-1 family	D7RWD5	Brochothrix_phage	9.8e-41	52.0
WP_002984401.1\|984577_984967_-	hypothetical protein	Q38611	Lactococcus_phage	3.5e-44	68.2
WP_111705644.1\|985308_985617_-	hypothetical protein	A0A2P1JTW8	Anoxybacillus_phage	4.3e-13	40.2
WP_002984392.1\|985613_985967_-\|head,tail	phage head-tail connector protein	A0A2H4J002	uncultured_Caudovirales_phage	9.7e-25	49.6
WP_002984390.1\|985980_986223_-	hypothetical protein	NA	NA	NA	NA
WP_002984386.1\|987306_987687_-	phage protein	A0A0K2CNR0	Brevibacillus_phage	5.2e-08	37.9
WP_111705645.1\|987696_988230_-	DUF4355 domain-containing protein	A0A141E0S7	Streptococcus_phage	1.4e-14	83.9
WP_002984382.1\|988341_989085_-	phage repressor protein/antirepressor Ant	M1PKL6	Streptococcus_phage	5.3e-73	56.9
WP_002984380.1\|989086_989335_-	hypothetical protein	NA	NA	NA	NA
WP_011017861.1\|989449_989629_-	hypothetical protein	M1NRK8	Streptococcus_phage	2.6e-18	79.7
WP_002984375.1\|989724_989994_-	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	2.3e-34	84.1
WP_010922213.1\|990053_990233_-	hypothetical protein	NA	NA	NA	NA
WP_002984371.1\|990223_991849_-\|head	phage head morphogenesis protein	U6E9F1	Streptococcus_phage	1.1e-46	43.8
WP_111705646.1\|991829_993332_-\|portal	phage portal protein	C9W9H5	Streptococcus_virus	2.4e-141	54.5
WP_111677299.1\|993343_994651_-\|terminase	PBSX family phage terminase large subunit	A0A2H4IYR5	uncultured_Caudovirales_phage	5.9e-184	75.2
WP_111705647.1\|994628_995099_-\|terminase	terminase small subunit	A0A141E1Y3	Streptococcus_phage	1.0e-50	70.2
WP_111677301.1\|995628_996069_-	ArpU family transcriptional regulator	Q938L8	Temperate_phage	7.2e-78	97.3
WP_002987471.1\|996339_996975_-	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	5.5e-87	67.9
WP_111705648.1\|996974_997367_-	hypothetical protein	NA	NA	NA	NA
WP_032465979.1\|997379_997580_-	hypothetical protein	A0A0E3T873	Gordonia_phage	4.6e-08	45.3
WP_111677589.1\|997584_997869_-	hypothetical protein	A0A097PAV1	Streptococcus_pyogenes_phage	2.6e-36	86.2
WP_172453938.1\|997865_998036_-	hypothetical protein	Q938M0	Temperate_phage	8.5e-11	100.0
WP_111677303.1\|998032_998446_-	hypothetical protein	Q938M1	Temperate_phage	4.6e-34	62.4
WP_023078268.1\|998429_998717_-	DUF1599 domain-containing protein	J7KDH9	Streptococcus_phage	5.1e-32	75.0
WP_111677305.1\|998958_999315_-	hypothetical protein	A0A1P8VVP9	Streptococcus_phage	2.1e-59	97.5
WP_011018139.1\|999311_999752_-	RusA family crossover junction endodeoxyribonuclease	A0A097PAS0	Streptococcus_pyogenes_phage	1.6e-80	98.6
WP_011106686.1\|999751_999955_-	hypothetical protein	Q938M6	Temperate_phage	4.7e-32	100.0
WP_111677307.1\|999960_1000380_-	single-stranded DNA-binding protein	Q938M7	Temperate_phage	3.1e-70	97.1
WP_111705649.1\|1000372_1001047_-	ERF family protein	Q938M8	Temperate_phage	5.8e-103	96.9
WP_021341163.1\|1001047_1001530_-	siphovirus Gp157 family protein	Q938M9	Temperate_phage	1.6e-49	98.8
WP_111677309.1\|1001550_1001805_-	hypothetical protein	Q938N0	Temperate_phage	1.8e-41	97.6
WP_011285579.1\|1001785_1002139_-	hypothetical protein	A0A097PAU3	Streptococcus_pyogenes_phage	2.8e-16	54.0
WP_111705650.1\|1002279_1003062_-	ATP-binding protein	A0A097PAQ0	Streptococcus_pyogenes_phage	1.8e-143	97.3
WP_009881060.1\|1003048_1003879_-	phage replisome organizer N-terminal domain-containing protein	A0A1S5S918	Streptococcus_phage	6.4e-67	54.7
WP_023610888.1\|1003892_1004207_-	helix-turn-helix transcriptional regulator	A0A1P8VVN6	Streptococcus_phage	2.7e-50	95.2
WP_011017882.1\|1004353_1004650_-	hypothetical protein	A0A097PAT8	Streptococcus_pyogenes_phage	3.1e-48	98.0
WP_011054585.1\|1004728_1004914_-	helix-turn-helix transcriptional regulator	A0A1X9I6I3	Streptococcus_phage	3.3e-16	72.1
WP_011284879.1\|1005080_1005320_+	hypothetical protein	NA	NA	NA	NA
WP_038433319.1\|1005451_1005652_-	helix-turn-helix transcriptional regulator	A0A141E205	Streptococcus_phage	2.1e-08	61.4
WP_001008979.1\|1005703_1006345_+	hypothetical protein	J7KJ31	Streptococcus_phage	1.5e-116	100.0
WP_080286776.1\|1006443_1006602_-	hypothetical protein	J7KH24	Streptococcus_phage	6.4e-21	90.4
WP_021341080.1\|1006660_1006876_+	hypothetical protein	J7KBX0	Streptococcus_phage	2.5e-28	95.7
1007307:1007322	attL	NA	NA	NA	NA
WP_038433318.1\|1007366_1008191_+	helix-turn-helix transcriptional regulator	A0A097PBE5	Streptococcus_pyogenes_phage	8.4e-120	84.8
WP_002984270.1\|1008203_1009013_+	type II toxin-antitoxin system PemK/MazF family toxin	J7KDP1	Streptococcus_phage	3.8e-24	35.8
WP_038433317.1\|1009262_1010351_+\|integrase	site-specific integrase	Q38159	Streptococcus_phage	3.8e-205	100.0
WP_002989605.1\|1010625_1011246_+	DUF3862 domain-containing protein	NA	NA	NA	NA
WP_111705651.1\|1011502_1013767_-	glycogen/starch/alpha-glucan family phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	1.6e-11	43.7
1011495:1011510	attR	NA	NA	NA	NA
WP_111705652.1\|1013801_1015295_-	4-alpha-glucanotransferase	NA	NA	NA	NA
WP_002992583.1\|1015410_1016430_-	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	5.7e-17	27.8
WP_111705653.1\|1016672_1017920_+	extracellular solute-binding protein	NA	NA	NA	NA
WP_011184618.1\|1018193_1019555_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_002984240.1\|1019554_1020391_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_002989577.1\|1021866_1022850_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_002984219.1\|1022880_1024131_-	D-alanyl-lipoteichoic acid biosynthesis protein DltD	NA	NA	NA	NA
WP_111705654.1\|1024123_1024363_-	D-alanine--poly(phosphoribitol) ligase subunit DltC	NA	NA	NA	NA
WP_002994626.1\|1024380_1025637_-	D-alanyl-lipoteichoic acid biosynthesis protein DltB	NA	NA	NA	NA
WP_002984203.1\|1025633_1027172_-	D-alanine--poly(phosphoribitol) ligase subunit DltA	A0A2K9KZV5	Tupanvirus	5.0e-41	28.2
WP_002984200.1\|1027183_1027327_-	teichoic acid D-Ala incorporation-associated protein DltX	NA	NA	NA	NA
WP_002989569.1\|1027589_1029581_-	excinuclease ABC subunit B	NA	NA	NA	NA
WP_111694846.1\|1029773_1031948_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_002984187.1\|1031947_1032688_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.5e-35	42.1
WP_111690746.1\|1032827_1033523_+	nicotinamide riboside transporter PnuC	NA	NA	NA	NA
WP_002984154.1\|1033527_1033686_-	hypothetical protein	NA	NA	NA	NA
WP_021299234.1\|1033754_1035068_-	GTPase ObgE	NA	NA	NA	NA
WP_002984145.1\|1035124_1035253_-	DUF4044 domain-containing protein	NA	NA	NA	NA
WP_164552683.1\|1035496_1036838_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.8e-63	48.7
WP_002992869.1\|1037138_1038011_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_002984130.1\|1038234_1039545_+	C4-dicarboxylate ABC transporter	NA	NA	NA	NA
WP_111705655.1\|1039622_1039916_+\|transposase	transposase	NA	NA	NA	NA
WP_111705656.1\|1039948_1040302_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	2.0e-06	35.2
WP_030127115.1\|1040347_1040518_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	1.5e-07	46.3
WP_111702165.1\|1040557_1040671_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_5

1278951 : 1385599

115

Streptococcus_phage(57.81%)

tRNA,transposase,tail,portal,holin,capsid,bacteriocin,terminase,integrase,head

attL 1340086:1340103|attR 1391754:1391771

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000564846.1\|1278951_1280085_-\|transposase	ISAs1-like element IS1548 family transposase	NA	NA	NA	NA
WP_159331589.1\|1280485_1280647_-	hypothetical protein	NA	NA	NA	NA
WP_111677419.1\|1280666_1281917_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.6e-117	56.3
WP_023079269.1\|1281909_1282731_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	3.0e-37	36.4
WP_111705738.1\|1282794_1284423_-	ABC transporter permease	NA	NA	NA	NA
WP_002988881.1\|1284427_1285162_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.3e-27	28.1
WP_002983572.1\|1285195_1285462_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_030127293.1\|1285654_1287640_-	transketolase	NA	NA	NA	NA
WP_002983569.1\|1287857_1288502_-	fructose-6-phosphate aldolase	A0A0C5AMY8	Cyanophage	2.2e-43	44.2
WP_111705739.1\|1288627_1290127_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_111705887.1\|1290116_1291463_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_111705740.1\|1291571_1292273_-	aquaporin family protein	M1HWZ0	Paramecium_bursaria_Chlorella_virus	1.2e-29	37.2
WP_111705741.1\|1292274_1294113_-	type 1 glycerol-3-phosphate oxidase	NA	NA	NA	NA
WP_002983556.1\|1294128_1295655_-	glycerol kinase GlpK	NA	NA	NA	NA
WP_011054910.1\|1296014_1296407_-	PepSY domain-containing protein	NA	NA	NA	NA
WP_002983550.1\|1296533_1296791_-	DUF896 family protein	NA	NA	NA	NA
WP_111705742.1\|1296944_1298984_-\|tRNA	glycine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_011184849.1\|1299361_1300279_-\|tRNA	glycine--tRNA ligase subunit alpha	NA	NA	NA	NA
WP_002983542.1\|1300649_1301183_-	isoprenylcysteine carboxyl methyltransferase family protein	NA	NA	NA	NA
WP_011018088.1\|1301314_1302154_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	2.5e-50	40.3
WP_111705743.1\|1302276_1303425_-	N-acetylglucosamine-6-phosphate deacetylase	NA	NA	NA	NA
WP_111705744.1\|1303542_1305174_-	Na/Pi cotransporter family protein	A0A1B1ITU5	uncultured_Mediterranean_phage	2.7e-05	38.8
WP_002994282.1\|1305375_1306098_+	hypothetical protein	NA	NA	NA	NA
WP_002988852.1\|1306226_1307069_-	DegV family protein	A0A1X9I5J4	Streptococcus_phage	1.3e-91	61.9
WP_010922569.1\|1307361_1307919_+	TetR/AcrR family transcriptional regulator	A0A1X9I6A2	Streptococcus_phage	3.2e-14	60.3
WP_002988848.1\|1307954_1308779_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_002983523.1\|1308780_1309398_-	trimeric intracellular cation channel family protein	NA	NA	NA	NA
WP_002983521.1\|1309594_1310572_-	tagatose-bisphosphate aldolase	NA	NA	NA	NA
WP_011054919.1\|1310721_1311072_-	tagatose-6-phosphate kinase	NA	NA	NA	NA
WP_023609931.1\|1311081_1311597_-	galactose-6-phosphate isomerase subunit LacB	NA	NA	NA	NA
WP_011054921.1\|1311611_1312037_-	galactose-6-phosphate isomerase subunit LacA	A0A222YX14	Synechococcus_phage	1.4e-06	27.9
WP_011184858.1\|1312293_1313745_-	PTS galactitol transporter subunit IIC	NA	NA	NA	NA
WP_011054923.1\|1313770_1314076_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_111705745.1\|1314068_1314542_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_111705746.1\|1314778_1315549_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	6.4e-21	27.8
WP_002994306.1\|1315752_1315956_-	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_038433539.1\|1315969_1318201_-	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	2.6e-115	37.5
WP_011018099.1\|1318200_1318635_-	CopY/TcrY family copper transport repressor	NA	NA	NA	NA
WP_111705747.1\|1318806_1319796_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_002988820.1\|1319926_1320277_-	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_111705748.1\|1320482_1323344_-	translation initiation factor IF-2	E3T4N3	Cafeteria_roenbergensis_virus	4.5e-19	25.2
WP_002983488.1\|1323363_1323666_-	YlxQ-related RNA-binding protein	NA	NA	NA	NA
WP_002983486.1\|1323658_1323955_-	YlxR family protein	NA	NA	NA	NA
WP_002988817.1\|1323970_1325128_-	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_002988815.1\|1325302_1325839_-	ribosome maturation factor RimP	NA	NA	NA	NA
WP_002983481.1\|1326083_1326263_-	hypothetical protein	A3F673	Streptococcus_phage	5.2e-19	79.7
WP_002983479.1\|1326329_1327124_-	DNA/RNA non-specific endonuclease	A7J2B8	Streptococcus_phage	8.9e-26	35.6
WP_002983477.1\|1327368_1328583_-	glucosaminidase domain-containing protein	A0A1P8VVM5	Streptococcus_phage	9.7e-165	60.5
WP_002983475.1\|1328694_1329150_-\|holin	phage holin family protein	A0A0M4R3G6	Streptococcus_phage	3.0e-63	81.5
WP_011054672.1\|1329160_1329775_-	DUF1366 domain-containing protein	Q938J7	Temperate_phage	1.8e-66	79.4
WP_111705749.1\|1329777_1330209_-	DUF1617 family protein	A3F661	Streptococcus_phage	7.6e-64	90.0
WP_111705750.1\|1330220_1332239_-	gp58-like family protein	Q938J9	Temperate_phage	3.0e-171	69.4
WP_111705642.1\|1332251_1333259_-	hyaluronoglucosaminidase	A7J2A8	Streptococcus_phage	2.6e-139	72.2
WP_111705643.1\|1333255_1335292_-\|tail	phage tail protein	A3F656	Streptococcus_phage	0.0e+00	84.1
WP_002984411.1\|1335288_1336068_-\|tail	phage tail family protein	A3F655	Streptococcus_phage	1.9e-68	55.5
WP_047235256.1\|1336099_1339366_-	tape measure protein	U6E979	Streptococcus_phage	1.6e-04	30.4
WP_002984407.1\|1339380_1339710_-	hypothetical protein	A0A1P8BLR3	Lactococcus_phage	2.0e-11	41.5
1340086:1340103	attL	NA	NA	NA	NA
WP_002984401.1\|1340818_1341208_-	hypothetical protein	Q38611	Lactococcus_phage	3.5e-44	68.2
WP_002984399.1\|1341204_1341570_-	HK97 gp10 family phage protein	A0A097BY98	Enterococcus_phage	7.7e-17	46.3
WP_002984392.1\|1341854_1342208_-\|head,tail	phage head-tail connector protein	A0A2H4J002	uncultured_Caudovirales_phage	9.7e-25	49.6
WP_002984388.1\|1342474_1343551_-\|capsid	major capsid protein	A0A2H4J022	uncultured_Caudovirales_phage	5.5e-103	56.0
WP_002984386.1\|1343550_1343931_-	phage protein	A0A0K2CNR0	Brevibacillus_phage	5.2e-08	37.9
WP_111705645.1\|1343940_1344474_-	DUF4355 domain-containing protein	A0A141E0S7	Streptococcus_phage	1.4e-14	83.9
WP_002984382.1\|1344585_1345329_-	phage repressor protein/antirepressor Ant	M1PKL6	Streptococcus_phage	5.3e-73	56.9
WP_002984380.1\|1345330_1345579_-	hypothetical protein	NA	NA	NA	NA
WP_011017861.1\|1345693_1345873_-	hypothetical protein	M1NRK8	Streptococcus_phage	2.6e-18	79.7
WP_002984375.1\|1345968_1346238_-	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	2.3e-34	84.1
WP_010922213.1\|1346297_1346477_-	hypothetical protein	NA	NA	NA	NA
WP_002984371.1\|1346467_1348093_-\|head	phage head morphogenesis protein	U6E9F1	Streptococcus_phage	1.1e-46	43.8
WP_111705646.1\|1348073_1349576_-\|portal	phage portal protein	C9W9H5	Streptococcus_virus	2.4e-141	54.5
WP_111677299.1\|1349587_1350895_-\|terminase	PBSX family phage terminase large subunit	A0A2H4IYR5	uncultured_Caudovirales_phage	5.9e-184	75.2
WP_044564892.1\|1350872_1351340_-\|terminase	terminase small subunit	A0A141E1Y3	Streptococcus_phage	1.1e-52	70.8
WP_001132273.1\|1351402_1351588_+	type II toxin-antitoxin system HicA family toxin	D6PSW1	Lactobacillus_phage	1.7e-09	54.0
WP_002987543.1\|1351639_1352017_+	type II toxin-antitoxin system HicB family antitoxin	I3NLB2	Bifidobacterium_phage	3.3e-15	44.0
WP_002990048.1\|1352332_1352545_+	hypothetical protein	NA	NA	NA	NA
WP_011284864.1\|1352634_1353549_-	hypothetical protein	NA	NA	NA	NA
WP_011284866.1\|1354126_1354561_-	ArpU family transcriptional regulator	J7KDQ1	Streptococcus_phage	6.2e-74	97.9
WP_010922070.1\|1354834_1355470_-	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	2.0e-89	69.4
WP_111705751.1\|1355471_1355738_-	hypothetical protein	A7J287	Streptococcus_phage	1.6e-16	60.0
WP_002983415.1\|1355740_1355902_-	hypothetical protein	A7J285	Streptococcus_phage	1.2e-22	94.3
WP_002983414.1\|1355902_1357225_-	DEAD/DEAH box helicase family protein	A7J284	Streptococcus_phage	4.6e-253	98.0
WP_002983413.1\|1357221_1357497_-	VRR-NUC domain-containing protein	A7J283	Streptococcus_phage	8.6e-45	96.7
WP_002983412.1\|1357862_1360247_-	DNA primase	A7J282	Streptococcus_phage	8.8e-287	97.6
WP_002983411.1\|1360251_1362183_-	DNA polymerase	A7J280	Streptococcus_phage	0.0e+00	87.8
WP_002983410.1\|1362225_1362789_-	DUF2815 family protein	D2J040	Enterococcus_phage	7.4e-51	57.9
WP_002983409.1\|1362802_1363960_-	DUF2800 domain-containing protein	A7J278	Streptococcus_phage	1.7e-219	99.7
WP_002983408.1\|1363959_1364259_-	hypothetical protein	A7J277	Streptococcus_phage	1.0e-38	92.9
WP_002983407.1\|1364346_1364550_-	hypothetical protein	A7J276	Streptococcus_phage	9.4e-33	100.0
WP_002983406.1\|1364546_1364699_-	hypothetical protein	A7J275	Streptococcus_phage	4.4e-19	100.0
WP_111705752.1\|1364695_1365079_-	hypothetical protein	A7J274	Streptococcus_phage	6.1e-65	99.2
WP_002983404.1\|1365075_1365282_-	hypothetical protein	NA	NA	NA	NA
WP_002983403.1\|1365274_1365445_-	hypothetical protein	A7J273	Streptococcus_phage	2.0e-20	89.3
WP_032467257.1\|1365441_1365717_-	DNA-binding phage protein	A7J272	Streptococcus_phage	1.7e-45	95.6
WP_002983400.1\|1365775_1365985_-	helix-turn-helix transcriptional regulator	M1Q1B4	Streptococcus_phage	7.7e-14	53.6
WP_002983399.1\|1366275_1366623_+	helix-turn-helix transcriptional regulator	A0A126GGQ7	Streptococcus_phage	1.5e-41	73.5
WP_111705753.1\|1366626_1367013_+	ImmA/IrrE family metallo-endopeptidase	Q7Y4M1	Streptococcus_phage	2.2e-38	58.4
WP_002983395.1\|1367137_1368859_+	AAA family ATPase	NA	NA	NA	NA
WP_111705754.1\|1368915_1369773_+	DNA adenine methylase	A0A2H4UUI2	Bodo_saltans_virus	9.9e-15	29.3
WP_002983389.1\|1369893_1370973_+\|integrase	site-specific integrase	A7J266	Streptococcus_phage	7.5e-177	93.3
WP_002983387.1\|1371170_1371806_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_002983385.1\|1371805_1372597_-	phosphotransferase family protein	NA	NA	NA	NA
WP_023079963.1\|1372660_1373695_-	ABC transporter permease	NA	NA	NA	NA
WP_002983379.1\|1373697_1374423_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	3.9e-20	28.0
WP_002983376.1\|1374494_1374914_+	HIT family protein	NA	NA	NA	NA
WP_002988657.1\|1374910_1375267_+	hypothetical protein	NA	NA	NA	NA
WP_111705755.1\|1375377_1376628_-	LCP family protein	NA	NA	NA	NA
WP_002983369.1\|1376636_1377161_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002983367.1\|1377135_1377597_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_111705756.1\|1377750_1379211_-	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	2.9e-38	29.5
WP_011054931.1\|1379474_1380287_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_002983363.1\|1380638_1381631_+	PTS mannose transporter subunit IIAB	NA	NA	NA	NA
WP_002983360.1\|1381719_1382529_+	PTS mannose/fructose/sorbose transporter subunit IIC	NA	NA	NA	NA
WP_002983356.1\|1382545_1383457_+	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_020905408.1\|1383570_1383930_+	DUF956 family protein	NA	NA	NA	NA
WP_111705757.1\|1384321_1385599_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	3.6e-93	49.6
1391754:1391771	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1714595 : 1730328

Streptococcus_phage(61.54%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014411911.1\|1714595_1715387_-	helix-turn-helix transcriptional regulator	A0A1S5SE31	Streptococcus_phage	7.5e-09	48.5
WP_003045754.1\|1715454_1715712_+	hypothetical protein	NA	NA	NA	NA
WP_011185070.1\|1715766_1716174_+	hypothetical protein	A0A1X9I5V7	Streptococcus_phage	8.5e-49	68.7
WP_023080068.1\|1716187_1716805_+	Rha family transcriptional regulator	A0A159B6D5	Gordonia_phage	2.2e-11	38.8
WP_111681407.1\|1717050_1717383_+	hypothetical protein	NA	NA	NA	NA
WP_111705839.1\|1717379_1717601_+	hypothetical protein	NA	NA	NA	NA
WP_111681408.1\|1717603_1717795_+	hypothetical protein	NA	NA	NA	NA
WP_111705840.1\|1717806_1718136_+	hypothetical protein	NA	NA	NA	NA
WP_001100459.1\|1718138_1718411_+	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	6.1e-19	60.0
WP_111705841.1\|1718411_1719269_+	primase C-terminal domain-containing protein	A0A1X9I6L2	Streptococcus_phage	2.6e-124	74.8
WP_002992487.1\|1719237_1720926_+	DNA primase	A0A1X9I717	Streptococcus_phage	2.5e-259	82.1
WP_000694577.1\|1721212_1721386_+	hypothetical protein	A0A1X9I5U0	Streptococcus_phage	1.9e-10	59.6
WP_014407944.1\|1721391_1721565_+	hypothetical protein	NA	NA	NA	NA
WP_023611171.1\|1721566_1722076_+	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	1.1e-29	63.5
WP_002992480.1\|1722149_1722638_+	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	1.4e-45	54.9
WP_032461242.1\|1723037_1723400_+	DUF1492 domain-containing protein	A0A2H4JFS1	uncultured_Caudovirales_phage	1.3e-05	29.9
WP_111677542.1\|1723374_1723758_+	ArpU family transcriptional regulator	Q938L8	Temperate_phage	3.7e-14	41.7
WP_111677543.1\|1723958_1724621_+	hypothetical protein	NA	NA	NA	NA
WP_002982175.1\|1725017_1727573_-	DNA mismatch repair protein MutS	A0A1V0SGG8	Hokovirus	3.0e-43	23.4
WP_010922774.1\|1727559_1727766_-	YlbF family regulator	NA	NA	NA	NA
WP_002982171.1\|1727908_1728346_-	arginine repressor	NA	NA	NA	NA
WP_011018320.1\|1728636_1730328_+\|tRNA	arginine--tRNA ligase	A0A2I2L3K1	Orpheovirus	1.9e-73	32.4

Anti-CRISPR protein detection

Acr_ID: NZ_LS483415.1|WP_002983408.1|1363959_1364259_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_LS483415.1|WP_002983408.1|1363959_1364259_-|hypothetical-protein

1363959_1364259_-

99 aa aa

1278951-1385599

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_LS483415_1	Orphan	1.1\|779683\|30\|NZ_LS483415\|CRT	779683-779712	30	1331436-1331407	1

1. spacer 1.1|779683|30|NZ_LS483415|CRT matches to NZ_LS483415 position: 1331436-1331407, mismatch: 1

cttacgagctgagtttactcgtagtaatca	CRISPR spacer
cttacgtgctgagtttactcgtagtaatca	Protospacer
****** ***********************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LS483415

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information