CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483420	Streptococcus pyogenes strain NCTC13739 chromosome 1	1 crisprs	DEDDh,cas3,csm6,DinG,csa3	0	0	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483420_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483420_1

751442-751719

Orphan

Consensus_repeat	Method
GGACCTAAGGGAGACCGAGGTGAAACCGGCCCAGC	PILER-CR

3 spacers

The CRISPR arrays of NZ_LS483420_1

>merge|NZ_LS483420|1|751442-751719|PILER-CR
GGTCCTAAGGGAGACCGAGGTGAAACCGGCCCAGCCGGAGAACGTGGTGAACAAGGTCCTAAAGGAGATGCTGGAGCACAAGGTCCAATGGGGCCAGCTGGACCTGCCGGAGAACGTGGTGAAAAAGGAGAGCAAGGTAAGCAGGGTCTTCCTGGTACTCCTGGACTTAAAGGAGACCGAGGTGAAACCGGCCCAGCAGGCAAAGATGGTGAAGCTGGAGCACAAGGACCAGTGGGACCAGCCGGTCCTAAGGGAGACCGAGGTGAAACCGGCCCAGC

>NZ_LS483420|1|1|751442-751719|PILER-CR
GGTCCTAAGGGAGACCGAGGTGAAACCGGCCCAGC	CGGAGAACGTGGTGAACAAGGTCCTAAAGGAGATGCTGGAGCACAAGGTCCAATGGGGCCAGCT
GGACCTGCCGGAGAACGTGGTGAAAAAGGAGAGCA	AGGTAAGCAGGGTCTTCCTGGTACTCCTGGACTTAAAG
GAGACCGAGGTGAAACCGGCCCAGCAGGCAAAGAT	GGTGAAGCTGGAGCACAAGGACCAGTGGGACCAGCCGGTCCTAAGG
GAGACCGAGGTGAAACCGGCCCAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483420.1\|WP_111684822.1\|748412_748955_+\|ClbS/DfsB-family-four-helix-bundle-protein	unknown	unknown	gnl\|CDD\|226733
NZ_LS483420.1\|WP_002984103.1\|742962_744246_+\|3-phosphoshikimate-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|235037
NZ_LS483420.1\|WP_002984100.1\|741024_741885_+\|methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|180918
NZ_LS483420.1\|WP_002984095.1\|739174_739717_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_LS483420.1\|WP_011888813.1\|761189_762674_-\|DUF1846-domain-containing-protein	unknown	unknown	gnl\|CDD\|184220
NZ_LS483420.1\|WP_014407653.1\|741886_742852_+\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
NZ_LS483420.1\|WP_136074174.1\|738211_738625_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483420.1\|WP_032460594.1\|758812_759460_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|188353
NZ_LS483420.1\|WP_002984109.1\|744937_746389_+\|LCP-family-protein	unknown	unknown	gnl\|CDD\|224235
NZ_LS483420.1\|WP_014407643.1\|767415_768729_+\|GTPase-ObgE	unknown	unknown	gnl\|CDD\|237046
NZ_LS483420.1\|WP_168693975.1\|765646_766989_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_LS483420.1\|WP_032460591.1\|756606_758808_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273736
NZ_LS483420.1\|WP_002989532.1\|767230_767359_+\|DUF4044-domain-containing-protein	unknown	unknown	gnl\|CDD\|338651
NZ_LS483420.1\|WP_002989310.1\|744238_744730_+\|shikimate-kinase	unknown	unknown	gnl\|CDD\|234654
NZ_LS483420.1\|WP_172454112.1\|749093_749624_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_LS483420.1\|WP_002989302.1\|739725_741009_+\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|226594
NZ_LS483420.1\|WP_053308406.1\|764866_765598_+\|rRNA-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|224108
NZ_LS483420.1\|WP_002989513.1\|760683_761085_+\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|224961
NZ_LS483420.1\|WP_032460592.1\|756306_756600_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483420.1\|WP_023078879.1\|764386_764752_-\|thioesterase-family-protein	unknown	unknown	gnl\|CDD\|227783

Protein	Function_ID	Function_description	E-value
NZ_LS483420.1\|WP_111684822.1\|748412_748955_+\|ClbS/DfsB-family-four-helix-bundle-protein	gnl\|CDD\|226733	COG4283, COG4283, Uncharacterized conserved protein [Function unknown].	3.36132e-75
NZ_LS483420.1\|WP_002984103.1\|742962_744246_+\|3-phosphoshikimate-1-carboxyvinyltransferase	gnl\|CDD\|235037	PRK02427, PRK02427, 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional.	0
NZ_LS483420.1\|WP_002984100.1\|741024_741885_+\|methionyl-aminopeptidase	gnl\|CDD\|180918	PRK07281, PRK07281, methionyl aminopeptidase.	0
NZ_LS483420.1\|WP_002984095.1\|739174_739717_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	1.44756e-30
NZ_LS483420.1\|WP_011888813.1\|761189_762674_-\|DUF1846-domain-containing-protein	gnl\|CDD\|184220	PRK13663, PRK13663, hypothetical protein; Provisional.	0
NZ_LS483420.1\|WP_014407653.1\|741886_742852_+\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	4.00956e-56
NZ_LS483420.1\|WP_023078879.1\|764386_764752_-\|thioesterase-family-protein	gnl\|CDD\|227783	COG5496, COG5496, Predicted thioesterase [General function prediction only].	1.03161e-50
NZ_LS483420.1\|WP_032460594.1\|758812_759460_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|188353	TIGR03608, L_ocin_972_ABC, putative bacteriocin export ABC transporter, lactococcin 972 group. A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate].	7.47854e-87
NZ_LS483420.1\|WP_002989310.1\|744238_744730_+\|shikimate-kinase	gnl\|CDD\|234654	PRK00131, aroK, shikimate kinase; Reviewed.	5.98224e-64
NZ_LS483420.1\|WP_014407643.1\|767415_768729_+\|GTPase-ObgE	gnl\|CDD\|237046	PRK12297, obgE, GTPase CgtA; Reviewed.	0
NZ_LS483420.1\|WP_168693975.1\|765646_766989_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	9.43217e-48
NZ_LS483420.1\|WP_032460591.1\|756606_758808_+\|hypothetical-protein	gnl\|CDD\|273736	TIGR01654, unnamed_protein_product, bacteriocin-associated integral membrane (putative immunity) protein. This model represents a family of integral membrane proteins, most of which are about 650 residues in size and predicted to span the membrane seven times. Nearly half of the members of this family are found in association with a member of the lactococcin 972 family of bacteriocins (TIGR01653). Others may be associated with uncharacterized proteins that may also act as bacteriocins. Although this protein is suggested to be an immunity protein, and the bacteriocin is suggested to be exported by a Sec-dependent process, the role of this protein is unclear. [Cellular processes, Toxin production and resistance].	3.22278e-15
NZ_LS483420.1\|WP_002989532.1\|767230_767359_+\|DUF4044-domain-containing-protein	gnl\|CDD\|338651	pfam13253, DUF4044, Protein of unknown function (DUF4044). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 42 and 56 amino acids in length. There is a single completely conserved residue M that may be functionally important.	4.98658e-06
NZ_LS483420.1\|WP_172454112.1\|749093_749624_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.58488e-07
NZ_LS483420.1\|WP_002989302.1\|739725_741009_+\|CBS-domain-containing-protein	gnl\|CDD\|226594	COG4109, COG4109, Predicted transcriptional regulator containing CBS domains [Transcription].	0
NZ_LS483420.1\|WP_053308406.1\|764866_765598_+\|rRNA-pseudouridine-synthase	gnl\|CDD\|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	2.25981e-90
NZ_LS483420.1\|WP_002989513.1\|760683_761085_+\|PaaI-family-thioesterase	gnl\|CDD\|224961	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis, transport, and catabolism].	8.88365e-25
NZ_LS483420.1\|WP_002984109.1\|744937_746389_+\|LCP-family-protein	gnl\|CDD\|224235	COG1316, LytR, Transcriptional regulator [Transcription].	3.50658e-64

>NZ_LS483420.1|WP_172454112.1|749093_749624_-|TetR/AcrR-family-transcriptional-regulator
MVSSDNTNLKFLKAFSELLKMRRFEQIKVSDLAKKAQLSRRAFYNHYNSKEDFLRESILIIFDDITKILNNDLLYEELVLKEMLSYMYINKEIIKSFVCFFPNIDNIIKNYIKGMIIHSDIPDLQKQLETAYQVPYSFALDIYISTIESIILNWIDNDFTESPEKIAKYITSVVRI
>NZ_LS483420.1|WP_111684822.1|748412_748955_+|ClbS/DfsB-family-four-helix-bundle-protein
MNQKEGEFSRTYENKEQLKAEIDKTFEKYISEFDIIPENLKDKRADEVDRTPAENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQELKAKLNENINFIYIMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIYVNTVAPFGTFRTKIRKWKKIVL
>NZ_LS483420.1|WP_002984109.1|744937_746389_+|LCP-family-protein
MTKYPMGGLSHHEELRYFYLLRNLSYLSENEKKEFAFLKSKLEIGRAYAPSKQHYRKSKRQEPYFEDDYYNDYSPNDLLEDDDVNHDSSFVPYGLPIYPKEDRYLNKKTKLTARRPIDAPQPIDEDDAFLTESVARCALPRSQKRKHKKKGCMKWFFNILGLLLMTVLMGLGLMFAKGVFDISTNKANYKPAVSQAFDGQETQDGTNILVLGSDQRVTQGSTDARTDTIMVVNVGNHAKKIKMVSFMRDTLINIPGYSYNDNSYDLKLNSAFNLGEQEDHHGAEYVRRALKHNFDIDIKYYVMVDFETFAEAIDTLFPNGVKIDAKFATVGGVAVDSVEVPDDLRMKNGVVPNQTIEVGEQRMDGRTLLNYARFRKDDEGDFGRTVRQQQVMSAVMSQIKDPTKLFTGSAAIGKIYALTSTNVSFPFVVKNGVSVLGSGKNGVEHVTIPENGDWVDEYDMYGGQALYIDFDKYQKTLAKLGLR
>NZ_LS483420.1|WP_002989310.1|744238_744730_+|shikimate-kinase
MTKVLLGFMGVGKTTVSKHLSMHCKDMDAIIEAKIGMSIAAFFEQHGEIAFRTIESQVLKDLLFANDNSVIVTGGGVVVLQENRQLLRKNHQHNILLVASFETLYQRLKHDKKSQRPLFLKYSKEAFYEFYQQRMVFYEGLSDLVIRVDHRTPEEVANIIEGY
>NZ_LS483420.1|WP_002984103.1|742962_744246_+|3-phosphoshikimate-1-carboxyvinyltransferase
MKLRTNAGPLQGTIQVPGDKSISHRAVILGAVAKGETRVKGLLKGEDVLSTIQAFRNLGVRIEEKDDQLVIEGQGFQGLTAPCQTLNMGNSGTSMRLIAGLLAGQPFSVKMIGDESLSKRPMDRIVYPLKQMGVEISGETDRQFPPLQLQGNRNLQPITYTLPISSAQVKSAILLAALQAKGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVGPQQLTAQEITVPGDISSAAFWLVAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQIVYEDMNKKEQVTSIRVVYSHLKGTIISGGLIPRLIDELPIIALLATQAQGTTCIKDAQELRVKETDRIQVVTDILNSMGANIKATADGMIIKGPTVLYGANTSTYGDHRIGMMTAIAALLVKQGQVHLDKEEAIMTSYPTFFKDLERLCHD
>NZ_LS483420.1|WP_014407653.1|741886_742852_+|YihY/virulence-factor-BrkB-family-protein
MAEKKWFDKVLSKWQYEPIQVFMRHLQSAEMDLSAIAVAYYLILTAFPLIVIAANIFPYLNIDIADLLRLMKQNLPKDIFRPTSAIVENIFSKPSGSVLGVATLTGLWTMSRSLTSLQKAINKAYGASQHRDFFIGHLVGLLTSLIILFLLAFALIFSTFSKAAIQVLDKHYHLSDNITTIFLLLIQPITVLIIFVGLMLLYFLLPNVKIKKIRYILPGTLFTSFVMTFLSNLVGNYVVYNVERMVDIKMFGSVMIFIIMLWFIFLARILILGAIFNATYQEMSLGKLEGRSGDMIAILKKTLGNDSDLSPSQSIEDSHTD
>NZ_LS483420.1|WP_002984100.1|741024_741885_+|methionyl-aminopeptidase
MITLKSAREIEAMDRAGDFLAGIHIGLRDIIKPGVDMWEVEAYVRRRCKEDNVLPLQIGVDGHMMDYPYATCCGLNDEVAHAFPRHYILKEGDLLKVDMVLSEPLDKSIVDVAALDFDNVPEMKKWTGSYTGGLADSCWAYAVGTPSDEIKQLMDVTKEAMYRGIEKAVIGNRIGDIGAAVQEYAESFGYGVVRDLVGHGVGPTMHEEPMVPNYGTAGRGLRLKEGMVLTVEPMINTGTWEIDTDIKTGWAHKTLDGGLSCQYEHQFVITKDGPVILTSQGEERTY
>NZ_LS483420.1|WP_002989302.1|739725_741009_+|CBS-domain-containing-protein
MSKHQDILDYLEKLAIGKKVSVRSISNHLKVSDGTAYRAIKEAENRGIVETKPRSGTVRIEKKGRVRIDRLTYSEIARISDSEVLAGHAGLGHEFSRFSIGAMTQQNIRRYLVKGGLLIVGDRETIQLLALENHNAILVTGGFPVSKRVIEMANNQRIPVMVTHYDTFTVATMINHALSNIRIKTDLKTVEQVMIPITDYGYLCEDSSVEEFNTLIKKTRQVRFPVLDYKRKVIGVVSMRDVVDQLPTTKLTKVMSKNPITARPNTSLANISQKMIFEDLNMLPVTDEENNLLGMITRRQAMENLPNHQPNNPYTYSEQILSNLEETVDYYQVVVEPTMIDSAGNMSNGVISEFLKEISIRALTKKHQKNIIIEQMMVYFLHAIQIEDELKIYPKIITENRRSSTIDIEIFVDDQVIAKAIITTKIN
>NZ_LS483420.1|WP_002984095.1|739174_739717_+|GNAT-family-N-acetyltransferase
MDIWTKLAVFAFFETPKVILRPFRYEDHWDFYSMVNDTKNLYYVFPEQKTKAASDYLLVHSFIKFPLGQWAIEDKATHQVIGSIRIEHYDAKTRCADIGYFLNYAFWGQGIMTEVVIKLVYLSFHEFGLKTLRIITHLENKASQKVAKKAGFQLKTCFKGSDRNTHKICIYKMYQLTNDR
>NZ_LS483420.1|WP_136074174.1|738211_738625_+|hypothetical-protein
MGTAVAYTEEIPTTPILTLEVTERREAINKINRLSDQYPNDPEIQATLEDTTNKILAFESADITEALIAEVNSEVTRLNEEKIARDAVDTAEKADAEKRHDFLKQQDAVTIAIQELANIPAKKTFRQYANDNGVDGV
>NZ_LS483420.1|WP_032460592.1|756306_756600_+|hypothetical-protein
MKNNIKKFISTSLIALTLAGAGGSIVSAATVYYNGTAVYWDYGRTAGLWSYSNVQSGVYEHSSTANGAFSGWKKPGVEARASKFIGNATAQCYWNCR
>NZ_LS483420.1|WP_032460591.1|756606_758808_+|hypothetical-protein
MTYKNMLLGKIRYLILFLVAIQSVLFALMAIFFTGVQYQESWQNYNRNSSTVTVYLQKLSDEQSQSVFRYFLEQNNLSIWTRRFETSEKGEGLSRIYVDILGNSEGFSDVVNTSKVVISRTQFKTLLEHDDNSLTIGLDKGSNNMLYELPSLLFTTPVVIDRLDYVFQKTNTINGTYYINGIKDRETEDDFLLGLSEITGITTDELTRESFGSSTDHGIWPIALAISIIVNSLIILVLLLICVLQSFKHFGILILLGWDRKALWNALFKKFLLFSIYITPVSASVLWLLSGWFSFGLPALFPIFAGTSLSILVLCLILIIPSIIVYLVSPLAAIHKRLPMKPLMVISLIFYVLVGVLLIAVSHSLDAPMNQFVDNIKVAREWKSVEDMYVISDFVEGNDIGIYSGTTNSLERDMYSFYQSISDLPGVYIAQGEYLDNQYLNTVQGTYQNVPSRPFWYLTYSYNYLSDFGVDLSEDELSEIKGGTRLYLIPETLSTAEIEVMKGYLQEIVTVKSGDIETRFTKNPTFLFKTYQPSNSIFTWSTSIANGVTSKEPIIFVASPENLYFMETANLFVSGYNGFLKFRDEKVMNQVKSILKNDFTNLSDNKLRFKTVKNYINGLQKNLSYTFYLFGSIIIIIVVTLIAIFWSFILVYQLLFEEKLYVQYFMGFSPWKRYILVISLIIGVSIIELLTSIILGSKLGIVLTLITTTFQMFFLYFNVFRKERGSILQSFKG
>NZ_LS483420.1|WP_032460594.1|758812_759460_+|ATP-binding-cassette-domain-containing-protein
MAMISVQNVSKKYGSRVIFKDLSFDVEEHEFVALVGPSGTGKSTLLNMIGLLDSFDSGSILINGKILPKVNSRAAVTYRKNVINYLFQSNALISTASVKDNLMLAMTFTDFSKQEKEKMIKDTLQFVNLENRLNSLVNELSGGEQQRIAIVRAILKPGNIILADEPTGSLDPDMAQKSFDLIRSLRDKFGKTIVIVTHNFEHAKQCDRVISLVSD
>NZ_LS483420.1|WP_002989513.1|760683_761085_+|PaaI-family-thioesterase
MSDLTQEMTLNVISIFDNYQIELAEKGHLILSTEVTETALNYYGNAHGGYLFTLCDQVGGLVARTTGVESVTLQANANYLKAGHKGDKLMVEGRLVHGGRTTQVVDVTIHNQTGALLTKISLTMFVTGRRHNG
>NZ_LS483420.1|WP_011888813.1|761189_762674_-|DUF1846-domain-containing-protein
MKTIAFDSNKYLNLQRDHILERISQFDGKLYMEFGGKMLEDYHAARVLPGYEPDNKIKLLKELKEQVEIVIAINANNIEHSKARGDLGISYDQEVFRLIDKFNTLDIYVGSVVITQYNNQPAADAFRKQLEKNGIASYLHYPIKGYPTDINHIISSEGMGKNDYIKTSRNLIVVTAPGPGSGKLATCMSQMYHDQINGVKSGYAKFETFPVWNLPLHHPVNLAYEAATADLDDVNMIDPFHLETYGKTAVNYNRDIEVFPVLNRTFERILSKSPYASPTDMGVNMVGFSIVNEEAAIEASKQEIIRRYYQTLVDFKAERVTESAVKKIELLMNDIGVTPDDRHVTVAAHQKAEQTGQPALALQLPNGQIVTGKTSELFGPTAAVIINAIKTLAKIDKTTHLIEPEYVKPIQGLKVNHLGSHNPRLHSNEILIALAITAMTSEEANLAMKELGNLKGSEAHSTVILTEEDKNVLRKLGVNITFDPVYQHHKLYRK
>NZ_LS483420.1|WP_023078879.1|764386_764752_-|thioesterase-family-protein
MTIYSHTYETRPNHSAKAMGSGTLNVLATPALVAFMENASYLFAQEQLDSDFTTVGSEIAIQHLAASAIGDPVTIIITALKEEGRKYDFRLEAFVREQLIGKACHTRVRVNSKHFMAKVAE
>NZ_LS483420.1|WP_053308406.1|764866_765598_+|rRNA-pseudouridine-synthase
MRLDKFLVATGVGTRSQVKLLLKKKAIFVNQKVETSAKAHIDEYKDLVTYQGTPLVYESFVYYLLNKPSGYVSATQDRQQATVMELLDDTARQKAVFPVGRLDKDTRGLLLLTNNGQLAHDLLSPKKHVTKEYLAKVAGIMTEADKDYFARGISLKDHQCLPAHLEVLASDLQQQTSLVKITIQEGKFHQVKRMVAACGKGVLDLQRLSMGPLKLDPSLAEGEFRRLTPEELQSLAPYCQSSL
>NZ_LS483420.1|WP_168693975.1|765646_766989_-|IS3-family-transposase
MKFNQETKVKIYELRQMGESIKSISKKFDMAESDLKYMIRLIDRYGVTIVQKCKNHYYSLELKQEIINKVLIDGQSQKQTSLDYALPTSSMLSRWIAQYKKNGYTILEKPKGRPSKMGRKRKKNLEEMTEVERLQKELEYPRAENAVLKKPERIPLEGRSKAQRATEIIQALRNQFPLEMLLEILDLSRSTYYYQVKRLAQGDKDIELKHVIREIYDEHKGNYGYRRIHMELRNRGFVVNHKKVQRLMKVMGLAARIRRKRKYSSYKGEVGKKADNLIKRHFEGSKPYEKCYTDVTELALPEGKLYLSPVFDSYNCEIIDFTLSRSPNLKQVQTMLEKTFPADSYSGTILHSDQGWQYQHQSYHDFLESKGILSSMSRKGNSPDNGMMDSFFGILKSEMFYGLEKSYKTLDKLEEAITDYISYYNNKRIKAKLKGLSPVQYRTKSFQ
>NZ_LS483420.1|WP_002989532.1|767230_767359_+|DUF4044-domain-containing-protein
MAFGENGPRKKTTFEKVTMFVVILMVLVTVGGLIASALSVLM
>NZ_LS483420.1|WP_014407643.1|767415_768729_+|GTPase-ObgE
MSMFLDTAKISVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGGSVIFRVDEGLRTLMDFRYNRKFKAKSGEKGMTKGMHGRGAEDLIVFVPQGTTVRDAETGKVITDLVEHGQEVVIAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKILADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGDSFAMADLPGLIEGASQGVGLGTQFLRHIERTRVILHVIDMSASEGRDPYEDYVSINNELETYNLRLMERPQIIVANKMDMPEAQENLKAFKKKLAAQYDEFDDLPMIFPISSLAHQGLENLLEATAELLAKTDEFLLYDESDLVDEEAYYGFAETEKDFEITRDDDATWVLSGEKLERLFVMTNMERDESIMKFARQLRGMGVDEALRERGAKDGDPVRIGKFEFEFVD

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

36645 : 48958

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025195412.1\|36645_40371_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	7.1e-41	27.4
WP_010921773.1\|40531_41986_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.8e-54	32.7
WP_111684458.1\|42013_43036_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	8.1e-64	42.0
WP_002986700.1\|43203_43758_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.4e-25	36.1
WP_076639719.1\|43941_45489_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	4.4e-45	52.4
WP_076639718.1\|45546_46671_-	SH3 domain-containing protein	F8HGP2	Streptococcus_phage	7.7e-07	28.6
WP_111684460.1\|46923_48189_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_111684462.1\|48466_48958_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.2e-18	42.3

DBSCAN-SWA_2

606314 : 661051

Streptococcus_phage(60.38%)

tail,integrase,holin,protease,portal,capsid

attL 624625:624644|attR 658827:658846

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002983882.1\|606314_608597_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A2C9CYX3	Yersinia_phage	1.1e-124	39.6
WP_002983885.1\|608894_609125_+	YkuJ family protein	NA	NA	NA	NA
WP_011054708.1\|609251_609938_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_009880900.1\|609937_610672_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.8e-34	38.8
WP_002993337.1\|610820_612230_+	deoxyribodipyrimidine photo-lyase	A0A1V0SGL1	Hokovirus	5.7e-60	32.8
WP_111684745.1\|612407_614102_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	1.6e-128	42.4
WP_010922486.1\|614309_615164_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	2.0e-39	39.8
WP_111681832.1\|615316_616657_+	exodeoxyribonuclease VII large subunit	A0A1V0SIT1	Klosneuvirus	2.2e-40	31.2
WP_002983901.1\|616634_616850_+	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_011284950.1\|616849_617722_+	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_111684747.1\|617714_618542_+	TlyA family RNA methyltransferase	NA	NA	NA	NA
WP_014407685.1\|618528_618999_+	arginine repressor	NA	NA	NA	NA
WP_002983909.1\|619020_620682_+	DNA repair protein RecN	NA	NA	NA	NA
WP_053308492.1\|620853_621801_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_002983913.1\|622016_622868_+	DegV family protein	A0A0N9SI50	Staphylococcus_phage	5.4e-13	35.7
WP_002992620.1\|622860_623703_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_002989129.1\|623680_624268_+	YpmS family protein	NA	NA	NA	NA
WP_002983920.1\|624366_624642_+	HU family DNA-binding protein	A7KV42	Bacillus_phage	2.6e-25	73.0
624625:624644	attL	NA	NA	NA	NA
WP_003051793.1\|624730_625873_-\|integrase	site-specific integrase	M1NRJ9	Streptococcus_phage	2.4e-173	77.4
WP_010922481.1\|625996_626515_-	restriction endonuclease	E8ZDN5	Streptococcus_phage	9.2e-32	45.9
WP_010922480.1\|626526_627282_-	helix-turn-helix transcriptional regulator	A0A1S5S8S8	Streptococcus_phage	2.8e-77	60.8
WP_010922479.1\|627484_627697_+	helix-turn-helix transcriptional regulator	A0A1X9I583	Streptococcus_phage	1.1e-10	56.7
WP_010922478.1\|627966_628278_+	excisionase	A0A1S5SA25	Streptococcus_phage	5.3e-43	77.7
WP_010922477.1\|628279_628465_+	hypothetical protein	Q938N3	Temperate_phage	1.3e-20	83.6
WP_011017564.1\|628968_629355_+	DnaD domain-containing protein	Q938N2	Temperate_phage	8.1e-25	51.9
WP_002988350.1\|629335_629569_+	hypothetical protein	Q938N1	Temperate_phage	1.8e-35	94.8
WP_011017992.1\|629565_629706_+	hypothetical protein	NA	NA	NA	NA
WP_011017565.1\|629714_629921_+	hypothetical protein	NA	NA	NA	NA
WP_063629030.1\|629976_630306_+	hypothetical protein	J7KGX3	Streptococcus_phage	6.4e-47	85.3
WP_002990071.1\|630308_631100_+	phage recombination protein Bet	A0A1S5SFP4	Streptococcus_phage	1.4e-119	82.0
WP_011888756.1\|631109_632138_+	DUF1351 domain-containing protein	E8ZD61	Streptococcus_phage	9.5e-121	65.9
WP_011888757.1\|632334_632676_+	hypothetical protein	M1NS23	Streptococcus_phage	3.1e-12	38.7
WP_111684749.1\|632672_633185_+	hypothetical protein	Q708P9	Streptococcus_phage	9.6e-66	77.4
WP_111684751.1\|633361_633631_+	hypothetical protein	A7J287	Streptococcus_phage	2.1e-27	76.4
WP_080465051.1\|633633_634383_+	site-specific DNA-methyltransferase	Q9MCL7	Streptococcus_virus	1.3e-130	89.5
WP_111684753.1\|634891_635311_+	DUF1492 domain-containing protein	A0A1X9I5B5	Streptococcus_phage	3.9e-57	79.9
WP_063629033.1\|635417_635762_+	HNH endonuclease	M1Q0W7	Streptococcus_phage	4.2e-41	68.5
WP_032461152.1\|635910_636267_+	hypothetical protein	A0A0B5A7G9	Streptococcus_phage	1.6e-14	47.8
WP_032461151.1\|636263_637532_+\|portal	phage portal protein	A0A1X9I693	Streptococcus_phage	2.0e-189	76.0
WP_111684755.1\|637524_639018_+	hypothetical protein	M1Q184	Streptococcus_phage	1.1e-88	55.6
WP_002994100.1\|639023_639248_+	hypothetical protein	NA	NA	NA	NA
WP_032461150.1\|639297_639477_+	hypothetical protein	NA	NA	NA	NA
WP_002986828.1\|639469_639736_+	hypothetical protein	Q938K9	Temperate_phage	6.4e-37	95.5
WP_011888764.1\|639737_639974_+	hypothetical protein	M1IRA5	Streptococcus_phage	1.2e-31	80.3
WP_063631462.1\|640055_641471_+	hypothetical protein	A0A0B5A091	Streptococcus_phage	9.1e-215	74.6
WP_032461147.1\|641541_642003_+	DUF4355 domain-containing protein	M1Q1L0	Streptococcus_phage	2.2e-37	52.6
WP_063631463.1\|642027_642939_+\|capsid	phage major capsid protein	M1PFL0	Streptococcus_phage	4.9e-113	67.0
WP_010922460.1\|642938_643139_+	hypothetical protein	NA	NA	NA	NA
WP_021733479.1\|643148_643571_+	phage protein Gp19/Gp15/Gp42	A0A0B5A2F6	Streptococcus_phage	8.2e-47	67.2
WP_011054681.1\|643530_643869_+	hypothetical protein	A0A0B5A086	Streptococcus_phage	8.1e-45	75.0
WP_111676592.1\|643861_644098_+	hypothetical protein	A0A1P8BMT2	Lactococcus_phage	1.1e-21	66.7
WP_000573598.1\|644098_644434_+	hypothetical protein	A0A1P8BMR5	Lactococcus_phage	9.8e-35	64.9
WP_111684757.1\|644445_645030_+\|tail	phage tail protein	M1NS84	Streptococcus_phage	1.0e-55	60.7
WP_032461128.1\|645039_645303_+	hypothetical protein	A0A0B5A2F3	Streptococcus_phage	6.5e-18	54.7
WP_032461127.1\|645317_645689_+	DUF5361 domain-containing protein	M1PL84	Streptococcus_phage	7.0e-34	60.0
WP_111676586.1\|645688_648052_+	hypothetical protein	M1NRG5	Streptococcus_phage	1.3e-133	50.6
WP_111676584.1\|648048_648744_+	hypothetical protein	A0A1B1P761	Bacillus_phage	6.2e-07	31.3
WP_172454111.1\|648725_650696_+\|tail	phage tail protein	Q938K1	Temperate_phage	1.4e-112	41.0
WP_111684761.1\|650692_651718_+	hyaluronoglucosaminidase	Q938K0	Temperate_phage	1.6e-173	93.8
WP_063631467.1\|651730_653671_+	gp58-like family protein	Q938J9	Temperate_phage	1.3e-168	71.4
WP_111684763.1\|653682_654111_+	DUF1617 family protein	Q938J8	Temperate_phage	4.4e-64	90.0
WP_011017396.1\|654113_654746_+	hypothetical protein	Q938J7	Temperate_phage	8.9e-45	50.0
WP_011017397.1\|654757_655030_+	hypothetical protein	A7J2B2	Streptococcus_phage	5.5e-36	91.0
WP_003058873.1\|655026_655254_+\|holin	phage holin	A7J2B3	Streptococcus_phage	2.0e-31	100.0
WP_014635574.1\|655372_656590_+	glucosaminidase domain-containing protein	A0A1P8VVM5	Streptococcus_phage	1.1e-163	60.1
WP_111684765.1\|656658_657366_-	streptococcal pyrogenic exotoxin SpeC	A0A097PAT7	Streptococcus_pyogenes_phage	2.3e-09	27.1
WP_111684767.1\|657476_658235_-	DNase Mf2	NA	NA	NA	NA
WP_014635572.1\|658474_658657_+	hypothetical protein	A3F673	Streptococcus_phage	1.7e-20	80.0
WP_111684768.1\|659188_661051_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	6.0e-89	34.1
658827:658846	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1140975 : 1151577

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011184383.1\|1140975_1142118_-	cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	1.4e-24	27.3
WP_012560601.1\|1142352_1142793_+	hypothetical protein	NA	NA	NA	NA
WP_111684985.1\|1142822_1144091_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_111684987.1\|1144178_1145531_-	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	3.1e-31	24.4
WP_002985134.1\|1145750_1146092_-	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	5.9e-19	40.2
WP_002990262.1\|1146152_1147319_-	chorismate synthase	A0A291AU41	Pandoravirus	4.5e-34	32.8
WP_002985140.1\|1147412_1148099_-	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.0e-88	68.9
WP_002985142.1\|1148095_1149259_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	3.4e-143	65.1
WP_111684989.1\|1149366_1151577_+	LTA synthase family protein	W6LM83	Streptococcus_phage	1.7e-268	69.1

DBSCAN-SWA_4

1436890 : 1442765

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021340916.1\|1436890_1437718_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	1.7e-128	79.9
WP_111685147.1\|1437791_1438148_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	2.4e-39	65.0
WP_011017427.1\|1438447_1439077_+	CutC family protein	NA	NA	NA	NA
WP_002985833.1\|1439123_1439516_-	hypothetical protein	NA	NA	NA	NA
WP_111685149.1\|1439542_1440406_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.9e-114	74.7
WP_002985838.1\|1440410_1440734_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.3e-28	59.4
WP_010921931.1\|1441236_1442112_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	7.7e-63	43.8
WP_111685152.1\|1442129_1442765_-	dTMP kinase	M1PSC7	Streptococcus_phage	7.8e-65	62.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage