CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483437	Streptococcus pyogenes strain NCTC13751 chromosome 1	3 crisprs	DinG,csm6,cas2,cas1,cas4,cas7,cas5,cas3,DEDDh,csa3	0	6	7	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483437_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483437_1

118266-118455

Orphan

Consensus_repeat	Method
AAGAAGTCCCAGAAGTTCCAAGCGAGAGCTTAGAACCTGCGCTTCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483437_1

>merge|NZ_LS483437|1|118266-118455|CRISPRCasFinder
AAGAAGTCCCAGAAGTTCCAAGCGAGAGCTTAGAACCTGCGCTTCCCCCATTGATGCCAGAGCTAGATGGTGAAGAAGTCCCAGAAGTTCCAAGCGAGAGCTTAGAACCTGCGCTTCCCCCATTAATGCCAGAGCTAGATGGCCAAGAAGTCCCAGAAGTTTCAAGCGAGAGCTTAGAACCTGCGCTTCC

>NZ_LS483437|1|1|118266-118455|CRISPRCasFinder
AAGAAGTCCCAGAAGTTCCAAGCGAGAGCTTAGAACCTGCGCTTCC	CCCATTGATGCCAGAGCTAGATGGTGAAGAAGTCCCAGAAGTTCCAAGCGAGAGCTTAGAACCTGCGCTTCCCCCATTAATGCCAGAGCTAGATGGCC
AAGAAGTCCCAGAAGTTTCAAGCGAGAGCTTAGAACCTGCGCTTCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483437.1\|WP_161237316.1\|131207_132614_+\|short-chain-fatty-acid-transporter	unknown	unknown	gnl\|CDD\|224942
NZ_LS483437.1\|WP_002986463.1\|132681_133593_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_LS483437.1\|WP_002986518.1\|110874_111168_+\|DUF4651-domain-containing-protein	unknown	unknown	gnl\|CDD\|339494
NZ_LS483437.1\|WP_002986515.1\|111164_111482_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_LS483437.1\|WP_076639394.1\|113592_114570_-\|tRNA-dihydrouridine-synthase-DusB	unknown	unknown	gnl\|CDD\|129820
NZ_LS483437.1\|WP_076639384.1\|133713_134898_+\|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl\|CDD\|180261
NZ_LS483437.1\|WP_172453926.1\|124973_130106_+\|fibrinogen-binding-adhesin-SdrG-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|380076
NZ_LS483437.1\|WP_076639397.1\|108533_109304_-\|pyrroline-5-carboxylate-reductase	unknown	unknown	gnl\|CDD\|237008
NZ_LS483437.1\|WP_076639395.1\|112931_113573_-\|deoxynucleoside-kinase	unknown	unknown	gnl\|CDD\|224345
NZ_LS483437.1\|WP_002986511.1\|111499_112126_+\|DUF4479-and-tRNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|239196
NZ_LS483437.1\|WP_012560390.1\|109351_110419_-\|glutamyl-aminopeptidase	unknown	unknown	gnl\|CDD\|132151
NZ_LS483437.1\|WP_076639389.1\|122247_123180_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|380024
NZ_LS483437.1\|WP_076639385.1\|130282_130948_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483437.1\|WP_003053955.1\|112276_112672_+\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|180914
NZ_LS483437.1\|WP_002986455.1\|134909_135569_+\|CoA-transferase-subunit-A	unknown	unknown	gnl\|CDD\|224702
NZ_LS483437.1\|WP_076639393.1\|115575_117069_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|285470
NZ_LS483437.1\|WP_076639387.1\|124046_124904_+\|class-C-sortase	unknown	unknown	gnl\|CDD\|320676
NZ_LS483437.1\|WP_087486702.1\|120455_122165_+\|SpaH/EbpB-family-LPXTG-anchored-major-pilin	unknown	unknown	gnl\|CDD\|275067
NZ_LS483437.1\|WP_168390471.1\|123157_124033_+\|class-C-sortase	unknown	unknown	gnl\|CDD\|320676
NZ_LS483437.1\|WP_002986499.1\|114556_115429_-\|Hsp33-family-molecular-chaperone-HslO	unknown	unknown	gnl\|CDD\|234643

Protein	Function_ID	Function_description	E-value
NZ_LS483437.1\|WP_161237316.1\|131207_132614_+\|short-chain-fatty-acid-transporter	gnl\|CDD\|224942	COG2031, AtoE, Short chain fatty acids transporter [Lipid metabolism].	0
NZ_LS483437.1\|WP_002986463.1\|132681_133593_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.29311e-29
NZ_LS483437.1\|WP_002986518.1\|110874_111168_+\|DUF4651-domain-containing-protein	gnl\|CDD\|339494	pfam15513, DUF4651, Domain of unknown function (DUF4651). family of short, secreted proteins specific to the Streptococcus genus, with distant homologs, not recognized by this HMM, found in other cocci. In all sequenced genomes, proteins from this family appear in a conserved genomic context with an thioredoxin, tRNA synthase and tRNA binding protein, but the functional implication of this is unclear.	8.86115e-29
NZ_LS483437.1\|WP_002986515.1\|111164_111482_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	1.40404e-25
NZ_LS483437.1\|WP_076639394.1\|113592_114570_-\|tRNA-dihydrouridine-synthase-DusB	gnl\|CDD\|129820	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family. This model represents one branch of COG0042 (Predicted TIM-barrel enzymes, possibly dehydrogenases, nifR3 family). This branch includes NifR3 itself, from Rhodobacter capsulatus. It excludes a broadly distributed but more sparsely populated subfamily that contains sll0926 from Synechocystis PCC6803, HI0634 from Haemophilus influenzae, and BB0225 from Borrelia burgdorferi. It also excludes a shorter and more distant archaeal subfamily.The function of nifR3, a member of this family, is unknown, but it is found in an operon with nitrogen-sensing two component regulators in Rhodobacter capsulatus.Members of this family show a distant relationship to alpha/beta (TIM) barrel enzymes such as dihydroorotate dehydrogenase and glycolate oxidase. [Unknown function, General].	8.16988e-121
NZ_LS483437.1\|WP_076639384.1\|133713_134898_+\|acetyl-CoA-C-acetyltransferase	gnl\|CDD\|180261	PRK05790, PRK05790, putative acyltransferase; Provisional.	0
NZ_LS483437.1\|WP_172453926.1\|124973_130106_+\|fibrinogen-binding-adhesin-SdrG-C-terminal-domain-containing-protein	gnl\|CDD\|380076	pfam17961, Big_8, Bacterial Ig domain. This entry represents a bacterial Ig-fold domain that is found in a wide range of bacterial cell surface adherence proteins.	5.91304e-18
NZ_LS483437.1\|WP_076639397.1\|108533_109304_-\|pyrroline-5-carboxylate-reductase	gnl\|CDD\|237008	PRK11880, PRK11880, pyrroline-5-carboxylate reductase; Reviewed.	5.48237e-107
NZ_LS483437.1\|WP_076639395.1\|112931_113573_-\|deoxynucleoside-kinase	gnl\|CDD\|224345	COG1428, COG1428, Deoxynucleoside kinases [Nucleotide transport and metabolism].	7.21551e-96
NZ_LS483437.1\|WP_002986511.1\|111499_112126_+\|DUF4479-and-tRNA-binding-domain-containing-protein	gnl\|CDD\|239196	cd02796, tRNA_bind_bactPheRS, tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain. PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate the 2'OH of the terminal ribose of tRNA they belong functionally to class 1 aaRSs. This domain has general tRNA binding properties and is believed to direct tRNAphe to the active site of the enzyme.	1.22775e-48
NZ_LS483437.1\|WP_012560390.1\|109351_110419_-\|glutamyl-aminopeptidase	gnl\|CDD\|132151	TIGR03107, Glutamyl_aminopeptidase, glutamyl aminopeptidase. This model represents the M42.001 clade within MEROPS family M42. M42 includes glutamyl aminopeptidase as in the present model, deblocking aminopeptidases as from Pyrococcus horikoshii and related species, and endo-1,4-beta-glucanase (cellulase M) as from Clostridium thermocellum. The current family includes [Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_LS483437.1\|WP_076639389.1\|122247_123180_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|380024	pfam17802, SpaA, Prealbumin-like fold domain. This entry contains a prealbumin-like domain from a wide variety of bacterial surface proteins. This entry corresponds to domain 1 and domain 3 of SpaA from Corynebacterium diphtheriae. Some members of this family contain an isopeptide bond.	2.27729e-13
NZ_LS483437.1\|WP_003053955.1\|112276_112672_+\|single-stranded-DNA-binding-protein	gnl\|CDD\|180914	PRK07274, PRK07274, single-stranded DNA-binding protein; Provisional.	1.44411e-89
NZ_LS483437.1\|WP_002986455.1\|134909_135569_+\|CoA-transferase-subunit-A	gnl\|CDD\|224702	COG1788, AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism].	4.65529e-110
NZ_LS483437.1\|WP_076639393.1\|115575_117069_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|285470	pfam08270, PRD_Mga, M protein trans-acting positive regulator (MGA) PRD domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This corresponds to the PRD like region.	6.59015e-61
NZ_LS483437.1\|WP_076639387.1\|124046_124904_+\|class-C-sortase	gnl\|CDD\|320676	cd05827, Sortase_C, Sortase domain found in class C sortases. Class C sortases are membrane-bound cysteine transpeptidases broadly distributed in Gram-positive bacteria (mainly present in Firmicutes and Actinobacteria). They function as pilin polymerases responsible for the assembly of pili, which are multi-subunit hair-like fibres that extend from the cell surface to promote microbial adhesion and biofilm formation. First, one or more class C sortases form the long thin shaft of the pilus through linking together pilin subunits via isopeptide bonds. The base of the pilus is then anchored to the cell wall by a housekeeping sortase or, in some cases, the class C sortase itself. Depending upon the organism both the number and type of sortase enzymes involved varies, and in some cases, accessory factors appear to be needed. In three-component spaA pilus from Corynebacterium diphtheriae, the prototypical class C sortase (named Cd-SrtA) catalyzes polymerization of the SpaA-type pilus, consisting of the shaft pilin SpaA, tip pilin SpaC and minor pilin SpaB. The pilus shaft is then attached to the cell wall by a housekeeping class E sortase, Cd-SrtF. In the absence of Cd-SrtF, Cd-SrtA attaches the pilus to the cell wall, albeit at a reduced rate. Cd-SrtA can recognize two distinct sorting signals (LPLTG in SpaA and SpaC, and LAFTG in SpaB) and it can employ lysine residues that originate from different proteins (either Lys190 within the pilin motif of SpaA or Lys139 in SpaB). However, Cd-SrtA cannot be able to polymerize the major pilin subunit SpaH, even though it contains LPLTG motif. In two-component pili of prototypical Bacillus cereus, the class C sortase (named Bc-SrtD) cleaves related sorting signals within a major pilin protein BcpA (LPVTG) and a minor tip pilin BcpB (IPNTG), and catalyzes a transpeptidation that joins the threonine residues in each signal to the side-chain of Lys162 in BcpA (located within a pilin motif). Unlike the SpaA pilus in C. diphtheriae, in B. cereus Bc-SrtD is unable to covalently attach the pilus to the cell wall without the help of the housekeeping sortase.	8.04292e-78
NZ_LS483437.1\|WP_087486702.1\|120455_122165_+\|SpaH/EbpB-family-LPXTG-anchored-major-pilin	gnl\|CDD\|275067	TIGR04226, Fimbrial_subunit_type_2, fimbrial isopeptide formation D2 domain. The Streptococcus Pneumoniae pilus backbone protein, RrgB, has three tandem domains with Lys-to-Asn isopeptide bonds, but these three regions are extremely divergent in sequence. This model represents the homology domain family of the D2 domain. It occurs just once in many surface proteins but up to twenty times in some pilin subunit proteins. Three of every four members have the typical Gram-positive C-terminal motif, LPXTG, although in many cases this motif may be involved in pilin subunit cross-linking rather than cell wall attachment. Proteins with this domain include fimbrial proteins with lectin-like adhesion functions, and the majority of characterized members are involved in surface adhesion to host structures.	7.8273e-16
NZ_LS483437.1\|WP_168390471.1\|123157_124033_+\|class-C-sortase	gnl\|CDD\|320676	cd05827, Sortase_C, Sortase domain found in class C sortases. Class C sortases are membrane-bound cysteine transpeptidases broadly distributed in Gram-positive bacteria (mainly present in Firmicutes and Actinobacteria). They function as pilin polymerases responsible for the assembly of pili, which are multi-subunit hair-like fibres that extend from the cell surface to promote microbial adhesion and biofilm formation. First, one or more class C sortases form the long thin shaft of the pilus through linking together pilin subunits via isopeptide bonds. The base of the pilus is then anchored to the cell wall by a housekeeping sortase or, in some cases, the class C sortase itself. Depending upon the organism both the number and type of sortase enzymes involved varies, and in some cases, accessory factors appear to be needed. In three-component spaA pilus from Corynebacterium diphtheriae, the prototypical class C sortase (named Cd-SrtA) catalyzes polymerization of the SpaA-type pilus, consisting of the shaft pilin SpaA, tip pilin SpaC and minor pilin SpaB. The pilus shaft is then attached to the cell wall by a housekeeping class E sortase, Cd-SrtF. In the absence of Cd-SrtF, Cd-SrtA attaches the pilus to the cell wall, albeit at a reduced rate. Cd-SrtA can recognize two distinct sorting signals (LPLTG in SpaA and SpaC, and LAFTG in SpaB) and it can employ lysine residues that originate from different proteins (either Lys190 within the pilin motif of SpaA or Lys139 in SpaB). However, Cd-SrtA cannot be able to polymerize the major pilin subunit SpaH, even though it contains LPLTG motif. In two-component pili of prototypical Bacillus cereus, the class C sortase (named Bc-SrtD) cleaves related sorting signals within a major pilin protein BcpA (LPVTG) and a minor tip pilin BcpB (IPNTG), and catalyzes a transpeptidation that joins the threonine residues in each signal to the side-chain of Lys162 in BcpA (located within a pilin motif). Unlike the SpaA pilus in C. diphtheriae, in B. cereus Bc-SrtD is unable to covalently attach the pilus to the cell wall without the help of the housekeeping sortase.	3.57205e-79
NZ_LS483437.1\|WP_002986499.1\|114556_115429_-\|Hsp33-family-molecular-chaperone-HslO	gnl\|CDD\|234643	PRK00114, hslO, Hsp33 family molecular chaperone HslO.	8.33794e-149

>NZ_LS483437.1|WP_076639393.1|115575_117069_-|helix-turn-helix-domain-containing-protein
MIEKYLESSIESKCQLIVLFFKTSYLPITEVAEKTGLTFLQLNHYCEELNAFFPGSLSMTIQKRMISCQFTHPFKETYLYQLYASSNVLQLLAFLIKNGSHSRPLTDFARSHFLSNSSAYRMREALIPLLRNFELKLSKNKIVGEEYRIRYLIALLYSKFGIKVYDLTQQDKNTIHSFLSHSSTHLKTSPWLSESFSFYDILLALSWKRHQFSVTIPQTRIFQQLKKLFVYDSLKKSSRDIIETYCQLNFSAGDLDYLYLIYITADNSFASLQWTPEHIRQCCQLFEENDTFRLLLNPIITLLPNLKEQKASLVKALMFFSKSFLFNLQHFIPETNLFVSPYYKGNQKLYTSLKLIVEEWMAKLPGKRYLNHKHFHLFCHYVEQILRNIQSPLVVVFVASNFINAHLLTDSFPRYFSDKSIDFHSYYLLQDNVYQIPNLKPDLVITHSQLIPFVHHELTKGIAVAEISFDESILSIQELMYQVKEEKFQADLTKQLT
>NZ_LS483437.1|WP_002986499.1|114556_115429_-|Hsp33-family-molecular-chaperone-HslO
MDKIIKSIAQSGAFRAYVLDSTETVALAQEKHNTLSSSTVALGRTLIANQILAANQKGDSKITVKVIGDSSFGHIISVADTKGHVKGYIQNTGVDIKKTATGEVLVGPFMGNGHFVTIIDYGTGNPYTSTTPLITGEIGEDFAYYLTESEQTPSAIGLNVLLDENDKVKVAGGFMVQVLPGASEEEIARYEKRLQEMPAISHLLASKNHVDALLEAIYGDEPYKRLSEEPLSFQCDCSRERFEAALMTLPKADLQAMIDEDKGAEIVCQFCGTKYQFNESDLEALINDKA
>NZ_LS483437.1|WP_076639394.1|113592_114570_-|tRNA-dihydrouridine-synthase-DusB
MIKLNSSFRIGDVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLVVMEMISEKGLLYNNEKTLHMLHIDENEHPMSIQLFGGDAEGLKRAADFIQTNTKADIVDINMGCPVNKVVKNEAGAKWLRDPDKIYHIVKEVTSVLDIPLTVKMRTGWADSSLAVENALAAESAGVSALAMHGRTREQMYTGTCDHETLARVSKAITKIPFIGNGDVRSVQDAKFMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGQELADLPFAKKLDIAKDHLKRLINLKGETIAVREFRGLAPHYLRGTAGAAKVRGAVSRAESLAEVEAIFETVR
>NZ_LS483437.1|WP_076639395.1|112931_113573_-|deoxynucleoside-kinase
MLIVLAGTIGAGKSSLAAALGEHLGTDVFYEAIDNNPVLDLYYQDPKKYAFLLQIYFLNKRFKSIKEAYQADNNILDRSIFEDEFFLKLNYKNGNVTKTELDIYQELLANMLEELEGMPKKRPDLLIYIDVSFDKMLERIEKRGRSFEQVDGNPSLEQYYHQVHGEYPTWYEDYKVSPKMKIDGNSLDFVQNPQDLATVLKMIDTKLKELHLL
>NZ_LS483437.1|WP_003053955.1|112276_112672_+|single-stranded-DNA-binding-protein
MYNKVIAIGRLVAKPELVKTATDKHVARLSLAVNRRFKNASGEREADFISVVVWGKLAETLVSYASKGSLMSIDGELRTRKYDKDGQVHYVTEVLCQSFQLLESRAQRAMRENNVTNDLVDLVLEEDTLPF
>NZ_LS483437.1|WP_002986511.1|111499_112126_+|DUF4479-and-tRNA-binding-domain-containing-protein
MIFAYNKEQVGDVLMVILQDTKDIKRQVERKGKVARVFAEESGKTLAWNIFEASSLITIEGNGQIFLTDEDLARLNAELAKEGFSERLEPTVGPVFVVGQIVEMVAHPDSDHLNICQVAIGEDQTVQIVAGAPNAALGLKTIVALPGAIMPNGSLIFPGKLRGEESYGMMCSPRELALPNAPQKRGIIELDESAVVGEAFDPAKHWKG
>NZ_LS483437.1|WP_002986515.1|111164_111482_+|thioredoxin-family-protein
MIRPTSYESLAALIEKEDKLVLFFTADWCPDCQFIYPIMPEIEAELTDMTFVCVNRDQFIEVAQKWDIFGIPSFVVIEKGQEVGRLVNKMRKTKTEIMHFLAAYQ
>NZ_LS483437.1|WP_002986518.1|110874_111168_+|DUF4651-domain-containing-protein
MRDMSKKKIGMISGIFGFSLAIGLGIVIKDYCQDRQRRQMTRDLRTFFSPLGQIEVLYINPCQVKQDYISGGVVMSNGKQYQFTYHSRQISFEEDKG
>NZ_LS483437.1|WP_012560390.1|109351_110419_-|glutamyl-aminopeptidase
MTDLFSKIKEVTELDGIAGYEHSVRDYLRTKITPLVDRVETDGLGGIFGIRDSKAEKAPRILVAAHMDEVGFMVSDIKVDGTLRVVGIGGWNPLVVSSQRFTLYTRTGQVIPLISGSVPPHFLRGANGSASLPHIEDIVFDGGFTDKAEAERFGITPGDIIVPQSETILTANQKNIISKAWDNRYGVLMITEMLEALKGQDLNNTLIAGANVQEEVGLRGAHVSTTKFDPELFFAVDCSPAGDIYGNPGTIGDGTLLRFYDPGHVMLKDMRDFLLTTAEDAGVNFQYYCGKGGTDAGAAHLQNGGVPSTTIGVCARYIHSHQTLYAMDDFVEAQAFLQAIIKKLDRSTVDLIKRY
>NZ_LS483437.1|WP_076639397.1|108533_109304_-|pyrroline-5-carboxylate-reductase
MKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLTLPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQDLPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRDLTDSFGSTFDINEKDFDTFTALAGSSPAYIYLFIEALAKAGVKNGMPKAKALEIVTQTVLASASNLKTSSQSPHDFIDAICSPGGTTIAGLMELERLGLTATVSSAIDKTIDKAKSL
>NZ_LS483437.1|WP_087486702.1|120455_122165_+|SpaH/EbpB-family-LPXTG-anchored-major-pilin
MKLSKKLSKKLSKKLLYSAMAFTMLTSATVAPVAQIIPSSTVRAETLQDRTQKTIPEATEVVITKLQADDYNDDVKPNGKANENGLPINNLGELGRNVKPLSDVTFVAYKIPEGIAEEKVKELKTKQTVVDVENYLNAQNLKIEKTVLTKTDGNGQTTFTVQKSSYGKYFVVEDMTATGTPETISKAYAVPFTLELPISASDGTGYLTKVNIYPKNVTSSLPKPGKDVKELGLNHSSYNIGERFSWFLKGTVPKNMLDYEKYSFTDTLDSQLDFISVKSVKYGSQILEKNNDYTLSEPTAQNRTLKVELTEAGIKKVAGLYPDRQEVLDTEIEAIKENTDQKPFLEVEFETNINSTVILGKPVTNEVKIEFDNKPDKIAKPVTTPPSDNPEVHTGGKRFVKVAAGNDATKLGGAEFDLLTEANQPINWTAELIRANNKSEYIVGTPQEGQPVKLKSDTDGSFEIKGLAYAIDAEATGAGVKYKLKETKAPAGYVIPEAPIEFAVNQTSYNKTPTTIDVDKADAEPQKVENNKRPEIPNTGGIGTAIFVVLGIVLMVVATKGMRSHKEEN
>NZ_LS483437.1|WP_076639389.1|122247_123180_+|LPXTG-cell-wall-anchor-domain-containing-protein
MQKLLKYLCSFGVVLGLLLGFPGQVLAQGDQAQLTVVHLESRDVDRPNPQLDLAPSAGKPVEGITYRLYQLKLGREAQPISYWEKLTLQALEEQAQTVFEAKTDAQGHAAFLQLPIGIYYGVAVENQQRQAGIAGFLVDLTGDTGYVKTVYPKVIWPTGGLHLIKYGVDGQTKVPLAGVRFELYEDNGFKPLRVKDGLHSYDLDAKTTLITNQEGQLKVAGLLAGNYYLKEVATAKGYRLKTDAISFQVQAHQTKTVSVDNQKEPPPPVTPWDWIPRTGEAQALTLIVLGLILMLLALFYYQKHRQEGND
>NZ_LS483437.1|WP_168390471.1|123157_124033_+|class-C-sortase
MVKRATISMETSKKKVELRVWLSRLVFLAGFLVLAFPIVSQVLYYQASRADINAFKQAVTKIDRTEIKRRLELARAYNASLSGGTNQTTKPVLKDPYSDHQKKAGRAEYSRMLEVREQIGHVTIPKINQDLPIYAGSGEENLQRGVGHLEGTSLPIGGPSTHAVLTAHRGLPTARLFTDLDKMRRGDRFYIEHLGGKLAYQVDSIKVITPDRLDELYLVPDKDYMTLLTCTPYMINSHRLLVRGKRIPYKESLKQKDQQIGQRHQLATYGFIALGLTLVLGLLWYRKRQKK
>NZ_LS483437.1|WP_076639387.1|124046_124904_+|class-C-sortase
MKQKVNQLYQLIATNKLRSVLFILGILVVLFPIVSQASYYLASHQQINQFEHKAAVIDRSAIERRISLAKAYNDAISRHPSLSDPFTSKEKAGLREYARMLEVNEQIGHVAIPKIGVDLPIYAGTSAAILEKGSGHLEGTSLPIGGKTTYAVLTAHRGLPTARLFTDLDKVKKGDYFYVTNLKGTLAYQVDRIMVIEPSQLDAVSIEEGKDYVTLLTCTPYMINSHRLLVRGVRVPLTSRQAKKESLTAVRPYQYYRWLVYLAIAVLIILVMIVAKYYQKTNKSS
>NZ_LS483437.1|WP_172453926.1|124973_130106_+|fibrinogen-binding-adhesin-SdrG-C-terminal-domain-containing-protein
MTNKTLHKVLVKLAAVLAILFLVLPTGLTAVTVLAEQINTENLIPVETAAGEILKESDLDFEQAIPTSGEALKDSSASWIQLTYNKVNQNLAKQDLFLRLPQGMTIEGIGQDQKLDVKTISVPKDLDLDEAASTINNTNIITGFEKIGEQDYKLSFAATSKTLNLVFKVKGTSLNEKRELQLSDKQNLNQTSFTKILGLGIAKSDDRTSANDTTTRPSIQPRAATDRETTGNQDISANLTTSNAQLNLEDKDKNNIYDVEAPDSFMFRATLSLLDSRYIVPGNYFELKLSDTIHYNMLNPTDINFPYLTQDGKVIAVPELVQDPPVDGLLRATGKIVRYRFTDQVQGLDSLTMTLNLGHSVNPNVVQNNDKYDFSYQIGGHIIKQSYDVQYGKPKENGNLNVHQRLTYTDSKQNLKASSLIYVNPKQTPQYAGKQTLSILRNPKTYTISEQTVPNLLELNNQTSIKVYKLKDSKGVTDAVNLDKQYLEEVINPIITKSDGKIEVSFNYTQGETSAYVVAVETSLQQEGSQPVFIAQNSNLTSASTRKKVSETDATATVGSGGSASGDQTPKGTLYLNKVDTNHKHLANATFTLSGNTTAGQFLYRTLITDTKEVSFSDLPPGSYLLKETTAPSGYQQITTPWTVTVDDKGKVTVTGNEADTQKVPEEAEVVILWESTKWNYGNVQFYKDRFKELVDSVGNQNAKYTLIRYSGDTSDSAQVINQSVSSAEFNKILNSETLTASTMTNRKGMLKAYQLALQQFQASTNKRKYLLQLTNYPIYPGYREEKDFMSQSQTSFDAMKSLGVVPYLLVERDPYANRNTYLDPKAEASSFGAFYPSDNIKVVWSNNSSGLFTPPTNTNYTIQIQSIGSAIKQQIPESVLTVINRASGKFSINKIDEAKKGLAGATFTLSKRTTVAVNHQVQGAFTPVSKETTAGRTTLTFDNLKPGVYDLKETKAPNAYVLDPKTYVVVVQNSGKTTIVDEANFKEADYPMADNTSQFDYPTKDIANKPNKIVFTKIGDGGKSLSGAEFELRKGNEKVQTTKSKDDGQVTFTKLLPGTYEVWETKVADSAYQLPKEAVATFEVKADGTFSEPMGRLFKKNSQQNNRYEIRNDLINKKTGNQKIKVIKKDELTEVPLPNAKFQLEASDGTIYTKTTDVKGEIVFEKLPYGQYILTEIEAPTGYVLDKTPQKINITEVSALETEVVAGRDATQPTVAPAARAALAAPVAEPVTGKNVSDQISIKELDITSSNEATPHNVRPNHGENIVMRADFTIKPGSDIKAGDFFTLTLPNTIDPFGVSAPENVDFRILGPLGTLALGTYDPSTHTITYKFTDYITRYAVSSFSTISPFFIDRYTVKTNQKIDLFLKIGQVSSDLYHFTVDYNPYYGIMDTDNPVNIGSIITRLNQDTGDFVNYVYINPAGQSLLDSTFTLTGNGSTILDNSTKVQVFEVNYPNIQMPPSWGIDDSSLTETNRYYINKQDGKISINFYNDLYLEKSYIVKISGKSDLTNNEPVHTSATLTQRRYISSAYWTHTGRYIPSGPYTETFTYNAGVLKRSGESNADGSVVVRLSNRKNYIDFMKSNSQGTPLEATFELRKKATNDMVTVGTPVISDKTTGKFYFEGLPPGDYEVWETKAPDGYTKPVEAVATFKVTDEGEIVDKSLEDGRIINYKRPELPATGGPGIFVYLFIGSSLCLVAFFWNRSSRFTR
>NZ_LS483437.1|WP_076639385.1|130282_130948_-|hypothetical-protein
MKRCNKYLFTSLLAASMLFSSYKSVHAHDNIDENGKVHLYWQGNYYVDNYVDYTKALVDSNNSIEWTVTFNSAKEQWVYPDFSVFLPKGVKAPKEITYEHHYWDGTVHSEKHNNTQWHYDWENQKTNFNQEFDKFPGYTGWSRSLDKFYKLKNDGKFSHVLVDTYGRQSHTYFSHKMVWKFKTELEEDYKNKWDKLPFIAGIKQNNPLAASFPSYKGEFGE
>NZ_LS483437.1|WP_161237316.1|131207_132614_+|short-chain-fatty-acid-transporter
MNNIKTKKRFMDRYIDGFMKWMPESLFICFILTFLVVTMSVLMTDSPFIGTEKTGGIIYGWVNGFWGLLSFAMQMTILLATGNAVASSPPAHKMFKSLAKLPQTRTQIFIFSIVVGSIFGFLHWGLGMMVAIVFGKELLVQARQKGIKVHTPLFVATLFFTFLPATSGLSGAAVLYSATPDYLRNSVADAYKQVVPESVPLTGSVLNLPFISLLVVCMLVPLCFALLAHPKDETKIMELDDEIYHHSLDTASHVVIARNTPAEKMNASRLVMYLVGGAIVSYSLYHFSVVGLSGLDLNSFNFLFLGLGLLLCGQQGPEYYGSLFKDGVMSSWGLVLQFPFYAGIFGIIQSTGLGLEISHFFVAISNGTTWPVFAYLYSALLNIAVPSGGSKFVIEAPYIVPATIEVGNDLGKILQAYQLGDATTNLIVPFWALSYLSNFKLKFNQIVAYTIPCVLVVTGIAIIYLFVF
>NZ_LS483437.1|WP_002986463.1|132681_133593_-|LysR-family-transcriptional-regulator
MNISSLAYFIEIVNCDFNLTKAAQKSHISQPALSSYIKTIEKEEGVVLFQRQKGRLVGLTSVGERFFENAKVVIASHEQLMADLRSESKKYKGEISIGIPQLISGIVFSELIPKLIEENPEVKFHIVETGAYELQKKLFLKEVDFAILLTPTTLDATIADIDILLRDQLCLYMSHKTFQETFDSNPNISIKALHRQNLVTFDKTFMINHQLTTLFEEANSLPVVKCYSASWDFLLNCTRYSSYLTILPRPITHFAHMDGLVEVQLTEHPKWEVVLASLKHNKTSHLKHYIKHTILDYFTNQRF
>NZ_LS483437.1|WP_076639384.1|133713_134898_+|acetyl-CoA-C-acetyltransferase
MTKEVVITSAYRTPIGNFGGVFKSLSAVDLGVTVVTKILADTGLKSDAIDEVIFGNVLHAGLGQNVARQVALNAGLSYDTPAFTIDMVCGSGLKAVELGAQKIQTGNADIVLVGGTENMSQAPYVLQGQRWGSRMGDSKVVDTMLKDGLSDAFAGYHMGITAENIVQQYGLTREEQDAFAADSQRKAQLAIEKGRFKEEIAPVTIPQRKGEPLLIDQDEYPKFGTTVDKLAKLRPAFIKDEGTVTAGNASGINDGAAAILLMSKEKAEELGLPILAKITSYASAGVDPSIMGCGPIPATKKALAKAQLTIDDIDLIEANEAFAAQALAVSRDLGFDNEKVNVNGGAIALGHPIGASGARILVTLLVEMAKRDVRHGLATLCIGGGQGQSIIVTR
>NZ_LS483437.1|WP_002986455.1|134909_135569_+|CoA-transferase-subunit-A
MKENKRIAIAEAISHIKDGDTIMVGGFMANGTPEALIDALVDKGTKDLTLICNDAGFVDRGVGKMVANHQFKTIYATHIGLNKEAGRQMTAGETTIELIPQGTFAEKIRIGAYGIGGFYTPTGVGTLVAEGKETKTIKGKTYLLEYPFEADVALIFANKADEMGNLQYSGSENNFNQLMAACAKTTIVQAREIVPVGTIQPECVHTPHIFVDYIVKEGV

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Crispr_ID: NZ_LS483437_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483437_2

1035393-1035494

Orphan

Consensus_repeat	Method
AATAATTGGTATAGTCTAATTATA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483437_2

>merge|NZ_LS483437|2|1035393-1035494|CRISPRCasFinder
AATAATTGGTATAGTCTAATTATACCGATAAAAACAGTATGTTTACAGTATATAATATCCACAATGTCTTGTCAAACATAAAATTGGTATAGTCTAATTATA

>NZ_LS483437|2|2|1035393-1035494|CRISPRCasFinder
AATAATTGGTATAGTCTAATTATA	CCGATAAAAACAGTATGTTTACAGTATATAATATCCACAATGTCTTGTCAAACA
TAAAATTGGTATAGTCTAATTATA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483437.1\|WP_002984451.1\|1033527_1035342_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_LS483437.1\|WP_076639671.1\|1036292_1037795_-\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235619
NZ_LS483437.1\|WP_031488247.1\|1030757_1031594_-\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270217
NZ_LS483437.1\|WP_002984433.1\|1043324_1044110_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483437.1\|WP_020905236.1\|1031609_1032239_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_LS483437.1\|WP_002984469.1\|1023109_1023358_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NZ_LS483437.1\|WP_076639672.1\|1046472_1048737_-\|glycogen/starch/alpha-glucan-family-phosphorylase	unknown	unknown	gnl\|CDD\|340853
NZ_LS483437.1\|WP_031488248.1\|1029614_1030388_-\|CAMP-factor-pore-forming-toxin-Cfa	unknown	unknown	gnl\|CDD\|369335
NZ_LS483437.1\|WP_002989605.1\|1045595_1046216_+\|DUF3862-domain-containing-protein	unknown	unknown	gnl\|CDD\|289729
NZ_LS483437.1\|WP_002984444.1\|1037857_1038871_-\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
NZ_LS483437.1\|WP_002989617.1\|1042245_1042617_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224639
NZ_LS483437.1\|WP_031488249.1\|1028009_1029245_+\|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|223131
NZ_LS483437.1\|WP_002984437.1\|1042616_1043315_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_LS483437.1\|WP_002989626.1\|1032996_1033332_-\|alkylphosphonate-utilization-protein	unknown	unknown	gnl\|CDD\|225380
NZ_LS483437.1\|WP_002992417.1\|1032248_1032890_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_LS483437.1\|WP_002984449.1\|1035517_1036075_-\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_LS483437.1\|WP_002989607.1\|1044240_1044855_-\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_LS483437.1\|WP_031488246.1\|1038950_1042061_-\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|180917
NZ_LS483437.1\|WP_031488251.1\|1023720_1026039_-\|DNA-helicase-PcrA	unknown	unknown	gnl\|CDD\|273429
NZ_LS483437.1\|WP_032460380.1\|1026567_1027890_+\|sodium:alanine-symporter-family-protein	unknown	unknown	gnl\|CDD\|224040

Protein	Function_ID	Function_description	E-value
NZ_LS483437.1\|WP_002984451.1\|1033527_1035342_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_LS483437.1\|WP_076639671.1\|1036292_1037795_-\|pyruvate-kinase	gnl\|CDD\|235619	PRK05826, PRK05826, pyruvate kinase; Provisional.	0
NZ_LS483437.1\|WP_031488247.1\|1030757_1031594_-\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270217	cd00996, PBP2_AatB_like, Polar amino acids-binding domain of ATP-binding cassette transporter-like systems that belong to the type 2 periplasmic binding fold protein superfamily. This subfamily includes periplasmic binding domain of ATP-binding cassette transporter-like systems that serve as initial receptors in the ABC transport of amino acids and their derivatives in eubacteria. After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically-located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The Abp proteins belong to the PBPI superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.49546e-109
NZ_LS483437.1\|WP_020905236.1\|1031609_1032239_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	6.31636e-109
NZ_LS483437.1\|WP_002984469.1\|1023109_1023358_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.43969e-13
NZ_LS483437.1\|WP_076639672.1\|1046472_1048737_-\|glycogen/starch/alpha-glucan-family-phosphorylase	gnl\|CDD\|340853	cd04300, GT35_Glycogen_Phosphorylase, glycogen phosphorylase and similar proteins. This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	0
NZ_LS483437.1\|WP_031488248.1\|1029614_1030388_-\|CAMP-factor-pore-forming-toxin-Cfa	gnl\|CDD\|369335	pfam07373, CAMP_factor, CAMP factor (Cfa). This family consists of several bacterial CAMP factor (Cfa) proteins which seem to be specific to Streptococcus species. The CAMP reaction is a synergistic lysis of erythrocytes by the interaction of an extracellular protein (CAMP factor) produced by some streptococcal species with the Staphylococcus aureus sphingomyelinase C (beta-toxin).	3.90909e-97
NZ_LS483437.1\|WP_002989605.1\|1045595_1046216_+\|DUF3862-domain-containing-protein	gnl\|CDD\|289729	pfam12978, DUF3862, Domain of Unknown Function with PDB structure (DUF3862). Structure 3D4E shared structural similarity to beta-lactamase inhibitory proteins (BLIP) which already include 1XXM, 1S0W, 1JTG, 2G2U, 2G2W, 2B5R, and 3due. All of structures are involved in beta-lactamase inhibitor complex. (REF http://www.topsan.org/Proteins/JCSG/3d4e).	6.81674e-87
NZ_LS483437.1\|WP_002984444.1\|1037857_1038871_-\|6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0
NZ_LS483437.1\|WP_002989617.1\|1042245_1042617_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	4.0536e-49
NZ_LS483437.1\|WP_031488249.1\|1028009_1029245_+\|cation-diffusion-facilitator-family-transporter	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	3.31574e-95
NZ_LS483437.1\|WP_002984437.1\|1042616_1043315_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	7.28377e-64
NZ_LS483437.1\|WP_002989626.1\|1032996_1033332_-\|alkylphosphonate-utilization-protein	gnl\|CDD\|225380	COG2824, PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism].	2.02984e-64
NZ_LS483437.1\|WP_002992417.1\|1032248_1032890_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	2.99371e-71
NZ_LS483437.1\|WP_002984449.1\|1035517_1036075_-\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.3728e-38
NZ_LS483437.1\|WP_002989607.1\|1044240_1044855_-\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.14841e-31
NZ_LS483437.1\|WP_031488246.1\|1038950_1042061_-\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|180917	PRK07279, dnaE, DNA polymerase III DnaE; Reviewed.	0
NZ_LS483437.1\|WP_031488251.1\|1023720_1026039_-\|DNA-helicase-PcrA	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_LS483437.1\|WP_032460380.1\|1026567_1027890_+\|sodium:alanine-symporter-family-protein	gnl\|CDD\|224040	COG1115, AlsT, Na+/alanine symporter [Amino acid transport and metabolism].	0

>NZ_LS483437.1|WP_002984451.1|1033527_1035342_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNLIKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNGVIENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKALSIIEGSYAFALMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDKVTVTDYDGKELIRDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRQLISTYADETGNVQVDPAIITSIQEADRLYILAAGTSYHAGFATKNMLEQLTDTPVELGVASEWGYHMPLLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSRESTYTMLIHAGPEIAVASTKAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKDLVAEKVQALLTTTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLIEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEGLDREGDDIIVNKVHPFLAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE
>NZ_LS483437.1|WP_002989626.1|1032996_1033332_-|alkylphosphonate-utilization-protein
MSLPNCLQCQSEYVYEDGLLLICPMCAFEWTPGEEATEEEGLVVLDSNGVRLSDGDTITVVKDLKVKGAPKDLKQGTRVKNIRLVEGDHNIDCKIDGFGAMKLKSEFVKKI
>NZ_LS483437.1|WP_002992417.1|1032248_1032890_-|amino-acid-ABC-transporter-permease
MTYIQQVLPSLLDGALVTLQVFFIVIILSIPLGAILAFLMKIPFKPLQWFLTLYVWMMRGTPLLLQLIFFYYVLPSVGISFDRMPAAILAFTLNYAAYFAEIFRGGIEAIPKGQYEAAKVLKLKPLQTIRYIILPQVFKIVLPSVFNEVINLVKDSSLVYVLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTIISKQVEKRFNYYQ
>NZ_LS483437.1|WP_020905236.1|1031609_1032239_-|amino-acid-ABC-transporter-ATP-binding-protein
MLELKNISKQFGQKTIFDGFNLTVQDGEVLSLVGPSGGGKTTLLRMLAGLESIDSGQVFYNGEDVGIDHLENRNLLGFVFQDFQLFPHLTVLDNLTLSPTITMGKQNVDAKEKALDLLTRLGLKEHAQVYPYSLSGGQKQRVALARAMMIDPQIIGYDEPTSALDPELRQTVEALIVQNREMGITQIVVTHDLVFAEAISDRIIRVNPK
>NZ_LS483437.1|WP_031488247.1|1030757_1031594_-|amino-acid-ABC-transporter-substrate-binding-protein
MIIKKRTVAILAIASSFFLVACQATKSLKSGDAWGVYQKQKSITVGFDNTFVPMGYKDESGKCKGFDIDLAKEVFHQYGLKVNFQAINWDMKEAELNNGKIDVIWNGYSITKERQDKVAFTDSYMRNEQIIVVKKRSDIKTISDMKHKVLGAQSASSGYDALLRTPKLLKDFIKNKDANQYETFTQAFIDLKSDRIDGILIDKVYANYYLAKEGQLENYRMIPTTFENEAFSVGLRKEDKTLQAKINRAFRVLYQSGKFQAISEKWFGDDVATANIKS
>NZ_LS483437.1|WP_031488248.1|1029614_1030388_-|CAMP-factor-pore-forming-toxin-Cfa
MKPKHLLCLSTVVAGLALFSTMTHSVLADDASNPDTVLMNNNQANLQRDALVQKLDEGHQQLEAIKHEAKGTDIEATINKAIDAVDHMKSSIRFNTETIYDFSSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIIDPFASVDAIKVQVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTRLERDKKVLGIKPFDVYNRLNKAITHAVGVQLNPTTTVQQVDDEVIAVQNALETALKS
>NZ_LS483437.1|WP_031488249.1|1028009_1029245_+|cation-diffusion-facilitator-family-transporter
MTQDPIANLKLARKGPIVSIIVYLSLSVAKLLAGYLLNASSLIADGFNNLSDIVGNVALLIGLHLASQPADANHKFGHWKIEDLSSLVTSFIMFLVGFQVLIHTIKSIFSGQQVDIDPLGAIVGIVSAFVMLGVYVFNKRLSKRVKSSALVAASKDNLADAVTSIGTSIAIIAASLHLPVIDHIAAMIITFFILKTAFDIFMESSFSLSDGFDSRHLKKYEKAILEIPKIVAVKSQRARTYGSNVYLDIVLEMNPDLSVYESHSITEKVEQLLSDQFSIYDIDIHVEPAMIPEEEIFDNVAKNLYRYEKLILSKVPDYDHYIAKSFQLIDANGQTVNYEQFLNQEIYYPSNFNHFQIESISQKTMLVTYQLNGNQHTSIWRRHESWSLLFHQITPIAKRQLHPTHYRIVKM
>NZ_LS483437.1|WP_032460380.1|1026567_1027890_+|sodium:alanine-symporter-family-protein
MIALVKLIDNLVWGPPLLILLVGTGIYLTSRLGLIQILKLPRAFKLIFSDDEGHGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGMATKYAEGVLAIKYRTKDANGHISGGPMYYIVNGMGTKWKPLAILFAGSGILVALFGIGTFAQVNSITSSLGHSFGLSPQMVSIVLAIFVAAIIFGGIHSISKVAEKVVPFMAIFYILSSLAVIFSHYQQLLPVIRLVFQSAFTPTAAIGGFTGSLMKDAIQKGIARGVFSNESGLGSAPIAAAAAKTNEPVEQGLISMTGTFIDTIIICTLTGLSILVTGQWTGQLEGAPLTQSAFATVFGNLGTFGLTFSLVLFAFTTILGWSYYGERCFEFLFGITHLTYFRIVFILMVGLGGFLKLELIWVLADIVNGLMALPNLIALLALSPVVILETKHYFIK
>NZ_LS483437.1|WP_031488251.1|1023720_1026039_-|DNA-helicase-PcrA
MNPLLNGMNDRQAQAVQTTEGPLLIMAGAGSGKTRVLTHRIAYLIDEKFVNPWNILAITFTNKAAREMKERALALNPATKDTLIATFHSMCVRILRREADHIGYNRNFTIVDPGEQRTLMKRILKQLNIDPKKWNERSILGTISNAKNDLLDEKGYEAQAADMYSQIVARCYKAYQEELRRSEALDFDDLIMMTLRLFDANPDVLAYYQQRYQYIHVDEYQDTNHAQYQLIKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVLLEENYRSTKKILQAANDVINNNRNRRPKKLWTQNADGEQLVYYRANDERDEAVFVASTISNMSQELGKNFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDLIAYLTIVANPADNISFERIVNEPKRGVGPGTLDKLRQFAYESDQSLLEAASNLLMSPLKGKAAQAIMDLANILGQLRQDLDQMSITDLAEALLEKTGYLDSLRLQNTLESQARIENIEEFLSVTKNFDESSASQEEDETGVDRLGRFLNDLALIADTDDSQAEAAEVTLMTLHAAKGLEFPVVFLIGMEEGVFPLSRASEDPDELEEERRLAYVGITRAEEVLFMTNANTRTLFGKSSYNRPTRFLKEISEELLSYKGLARPAQSSFGVRFSTETHTQFGQGMSLSEALQARKAQAQVRQSAQPMQAHTIPSASTSSVLPFGSNSSAEEVTWQIGDIAHHKKWGDGTVLEVSGSGKTMELKIKFPEVGLKKLLASVAPIEKK
>NZ_LS483437.1|WP_002984469.1|1023109_1023358_-|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MGLIWTLIVGALIGVIAGALTKKGGSMGWIANIAAGLVGSSVGQALLGSWGPSLAGMSLIPSVIGAVIVVMITSFVLNKTNN
>NZ_LS483437.1|WP_002984449.1|1035517_1036075_-|signal-peptidase-I
MVKRDFIRNILLLLIVIIGAILLRIFVFSTFKVSPETANTYLKSGDLVTIKKNIQPKYKDFVVYRVGKKDYVSRVIAVEGDSVTYMDDIFYLNNMVESQAYLEKMKAHYLNHAPFGTLYTDDFTVATITADKYQKVPKGKYLLLNDNRKNTNDSRRFGLINASQIKGLVTFRVLPLSDFGFVEVE
>NZ_LS483437.1|WP_076639671.1|1036292_1037795_-|pyruvate-kinase
MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAELIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFADDAKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKVIDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVEEVREICRETGNDHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGTDATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRVDSSAFPRTNKTDVIASAVKDATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAEKPASTDDMFEVAERVAVEAGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK
>NZ_LS483437.1|WP_002984444.1|1037857_1038871_-|6-phosphofructokinase
MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGMVDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSHGRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHIIVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVELLKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRSLSQ
>NZ_LS483437.1|WP_031488246.1|1038950_1042061_-|DNA-polymerase-III-subunit-alpha
MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLYGAYHFIKGCQKNGLQPVLGLEVEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKLHMDYLCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRYFAQDDMETLHMLHAIRDNLSLAETPVVESDQELTDCQQLTTFYQTHCPQALQNLEDLVSGIYYDFDTNLKLPHFNRDKSAKQELQELTEAGLKEKGLWKEPYQSRLLHELVIISDMGFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLNKERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGVPEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIHAAGIVMSDDTLTNHIPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEKVAKDYGCQIDIAAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVATTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYAGFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGFNRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSDYITDALESDFQVAQVTINSIPYTDKIEASKIYMGLKNIKGLPRDFAYWIIEQRPFNSVEDFLTRTPEKYQKKVFLEPLIKIGLFDCFEPNRKKIMDNLDGLLVFVNELGSLFSDSSFSWVDTKDYSATEKYSLEQEIVGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLSVNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKYWLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFVLKTVFR
>NZ_LS483437.1|WP_002989617.1|1042245_1042617_+|GntR-family-transcriptional-regulator
MSWKFDEKSPIYAQIAQHVMMQIISQEIKSGDQLPTVREYAEIAGVNPNTMQRAFTELEREGMVYSQRTAGRFVTDDQKLIARKRRELAISELESFITNMTKMGFSHTEIIPVLTSFLKEDSQ
>NZ_LS483437.1|WP_002984437.1|1042616_1043315_+|ABC-transporter-ATP-binding-protein
MAHLLQLHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKTTLIKLINGLLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSDFYSDFDKSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYVLDEPIGGVDPAARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFLKQGRLFLSGNADDLRQEYQQSIDSLFRETYKV
>NZ_LS483437.1|WP_002984433.1|1043324_1044110_+|hypothetical-protein
MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSDGLFGVLTNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGREGYLTLTLPVNSHQIILSKLLASFICSVFNTIILAFAIAIVIVPMFNINELLEGFFNSFKMDYFINMLTVLAYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILVILISVAATYVHSHIFNINTSADSFPFTEQKTIYLLILEQFIEMIMFYLATNFIIKNKLNLQ
>NZ_LS483437.1|WP_002989607.1|1044240_1044855_-|TVP38/TMEM64-family-protein
MTKRNSKAYILWQKIIKILGIIALIGTFFLAFWLYRLGILNDSNALKDLVQRYRLWGPFVFIVVQIIQIVFPVIPGGLTTVAGFLIFGPVTGFIYNYVGIIIGSIVLFLLVKTYGRKFILLFVNDKTFYKYERRLETPGYEKLFIFCMASPVSPADIMVMITGLTDMSLKRFVTILLITKPISIIGYSYLFIFGKDVISWFLQH
>NZ_LS483437.1|WP_002989605.1|1045595_1046216_+|DUF3862-domain-containing-protein
MTKKHLLTLLLISFFTSFLVACSTTKDKEPQPSDSEIITPRLHQAAHQDKRANFEKIKLATVDSSFTGGTSLEELISLFGEPSQHDPKTAGEVTIDAYTWQFDQVTLTVNLYQNSSIVKTISNFTFARELGLSQKEYQQLQKGMSYEDVKKILTEPDNYSQASSSDHQTLQAIWVSGLKTDTSGANISLVFENNQLTEMSQVGLEE
>NZ_LS483437.1|WP_076639672.1|1046472_1048737_-|glycogen/starch/alpha-glucan-family-phosphorylase
MTRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNSAKRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGLGRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFKHNEQEAEPNYWIEDQSWLVPTNISYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTQIAKNLTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLIIDEAIERGSNLHDLADYAYVQINDTHPSMVIPELIRLLTEKHGFDFDEAVAVVKNMVGYTNHTILAEALEKWPTAYLNEVVPHLVTIIEKLDALVRSEVSDPAVQIIDESGRVHMAHMDIHFATSVNGVAALHTEILKNSELKAFYDLYPEKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLMVFADDKAVHAKLAEIKFNNKLALKRYLKDNKDIELDEHSIIDTQIKRFHEYKRQQMNALYVIHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNVHLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAELAGMENIYTFGKDSDTIINLYATASYVAKDYYDNHPAIKAAVNFIISPELLAFGNEERLDRLYKELISKDWFMTLIDLEEYIEVKEKMLADYEDQDLWMTKVVHNIAKAGFFSSDRTIEQYNEDIWHSR

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Crispr_ID: NZ_LS483437_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483437_3

1328135-1328363

Unclear

I-C

Consensus_repeat	Method
ATTTCAATCCACTCACCCATGAAGGGTGAGAC	CRISPRCasFinder
ATTTCAATCCACTCACCCATGAAGGGTGAGAC	CRT
TTTCAATCCACTCACCCATGAAGGGTGAGAC	PILER-CR

3 spacers

cas2,cas1,cas4,cas7,cas5,cas3

The CRISPR arrays of NZ_LS483437_3

>merge|NZ_LS483437|3|1328135-1328363|CRISPRCasFinder,CRT,PILER-CR
CTTTCAATCCACTCACCCATGAAGGGTGAGACGCTGACTTTGATGTCGGTGCAGAACACGTTGGAATTTCAATCCACTCACCCATGAAGGGTGAGACGAAAAACATGCTGCGACTAAAAAATACGTAGATATTTCAATCCACTCACCCATGAAGGGTGAGACTCTCCATGCTCTTAATTCTTCAATTTTCTTTGTTCATTTCAATCCACTCACCCATGAAGGGTGAGAC

>NZ_LS483437|3|3|1328135-1328363|CRISPRCasFinder
CTTTCAATCCACTCACCCATGAAGGGTGAGAC	GCTGACTTTGATGTCGGTGCAGAACACGTTGGA
ATTTCAATCCACTCACCCATGAAGGGTGAGAC	GAAAAACATGCTGCGACTAAAAAATACGTAGAT
ATTTCAATCCACTCACCCATGAAGGGTGAGAC	TCTCCATGCTCTTAATTCTTCAATTTTCTTTGTTC
ATTTCAATCCACTCACCCATGAAGGGTGAGAC

>NZ_LS483437|3|1|1328135-1328363|CRT
CTTTCAATCCACTCACCCATGAAGGGTGAGAC	GCTGACTTTGATGTCGGTGCAGAACACGTTGGA
ATTTCAATCCACTCACCCATGAAGGGTGAGAC	GAAAAACATGCTGCGACTAAAAAATACGTAGAT
ATTTCAATCCACTCACCCATGAAGGGTGAGAC	TCTCCATGCTCTTAATTCTTCAATTTTCTTTGTTC
ATTTCAATCCACTCACCCATGAAGGGTGAGAC

>NZ_LS483437|3|1|1328136-1328363|PILER-CR
TTTCAATCCACTCACCCATGAAGGGTGAGAC	GCTGACTTTGATGTCGGTGCAGAACACGTTGGAA
TTTCAATCCACTCACCCATGAAGGGTGAGAC	GAAAAACATGCTGCGACTAAAAAATACGTAGATA
TTTCAATCCACTCACCCATGAAGGGTGAGAC	TCTCCATGCTCTTAATTCTTCAATTTTCTTTGTTCA
TTTCAATCCACTCACCCATGAAGGGTGAGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483437.1\|WP_002994841.1\|1327264_1327975_-\|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2	unknown	unknown	gnl\|CDD\|223856
NZ_LS483437.1\|WP_002986894.1\|1323183_1323564_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368753
NZ_LS483437.1\|WP_002986888.1\|1320902_1321052_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483437.1\|WP_076639349.1\|1336677_1339326_-\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_LS483437.1\|WP_003060901.1\|1329837_1330512_-\|CRISPR-associated-protein-Cas4	cas4	COG1468_cas4_CAS-I-A:CAS-I-B:CAS-I-C:CAS-I-D:CAS-II-B	gnl\|CDD\|224385
NZ_LS483437.1\|WP_011054768.1\|1322810_1323170_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_LS483437.1\|WP_002986891.1\|1321823_1322015_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483437.1\|WP_011888719.1\|1339327_1339891_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379082
NZ_LS483437.1\|WP_010922512.1\|1333254_1333983_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_LS483437.1\|WP_002986895.1\|1323574_1324096_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483437.1\|WP_076639346.1\|1328511_1328805_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|224262
NZ_LS483437.1\|WP_002983750.1\|1340905_1341160_-\|DUF1912-family-protein	unknown	unknown	gnl\|CDD\|286073
NZ_LS483437.1\|WP_076639344.1\|1325479_1326586_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|184456
NZ_LS483437.1\|WP_076639350.1\|1340492_1340888_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|181104
NZ_LS483437.1\|WP_011054767.1\|1321084_1321813_-\|phage-antirepressor-KilAC-domain-containing-protein	unknown	unknown	gnl\|CDD\|226091
NZ_LS483437.1\|WP_015057910.1\|1330513_1331362_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175
NZ_LS483437.1\|WP_076639348.1\|1334115_1336524_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_LS483437.1\|WP_031488520.1\|1328815_1329841_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_LS483437.1\|WP_002986896.1\|1324214_1325369_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_LS483437.1\|WP_076639345.1\|1326628_1327252_-\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264

Protein	Function_ID	Function_description	E-value
NZ_LS483437.1\|WP_002994841.1\|1327264_1327975_-\|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2	gnl\|CDD\|223856	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones].	4.54755e-43
NZ_LS483437.1\|WP_002986894.1\|1323183_1323564_+\|hypothetical-protein	gnl\|CDD\|368753	pfam06114, Peptidase_M78, IrrE N-terminal-like domain. This entry includes the catalytic domain of the protein ImmA, which is a metallopeptidase containing an HEXXH zinc-binding motif from peptidase family M78. ImmA is encoded on a conjugative transposon. Conjugating bacteria are able to transfer conjugative transposons that can, for example, confer resistance to antibiotics. The transposon is integrated into the chromosome, but during conjugation excises itself and then moves to the recipient bacterium and re-integrate into its chromosome. Typically a conjugative tranposon encodes only the proteins required for this activity and the proteins that regulate it. During exponential growth, the ICEBs1 transposon of Bacillus subtilis is inactivated by the immunity repressor protein ImmR, which is encoded by the transposon and represses the genes for excision and transfer. Cleavage of ImmR relaxes repression and allows transfer of the transposon. ImmA has been shown to be essential for the cleavage of ImmR. This domain is also found in in metalloprotease IrrE, a central regulator of DNA damage repair in Deinococcaceae, HTH-type transcriptional regulators RamB and PrpC.	0.00284034
NZ_LS483437.1\|WP_076639349.1\|1336677_1339326_-\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_LS483437.1\|WP_003060901.1\|1329837_1330512_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|224385	COG1468, COG1468, CRISPR-associated protein Cas4 (RecB family exonuclease) [Defense mechanisms].	1.18604e-43
NZ_LS483437.1\|WP_011054768.1\|1322810_1323170_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	8.27575e-08
NZ_LS483437.1\|WP_011888719.1\|1339327_1339891_-\|AAA-family-ATPase	gnl\|CDD\|379082	pfam13238, AAA_18, AAA domain.	0.00452424
NZ_LS483437.1\|WP_010922512.1\|1333254_1333983_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	3.32713e-117
NZ_LS483437.1\|WP_076639346.1\|1328511_1328805_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|224262	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms].	1.02794e-33
NZ_LS483437.1\|WP_002983750.1\|1340905_1341160_-\|DUF1912-family-protein	gnl\|CDD\|286073	pfam08930, DUF1912, Domain of unknown function (DUF1912). This domain has no known function. It is found in various Streptococcal proteins.	3.74168e-47
NZ_LS483437.1\|WP_076639344.1\|1325479_1326586_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|184456	PRK14018, PRK14018, bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB.	7.41609e-163
NZ_LS483437.1\|WP_076639350.1\|1340492_1340888_-\|hypothetical-protein	gnl\|CDD\|181104	PRK07758, PRK07758, hypothetical protein; Provisional.	0.000210941
NZ_LS483437.1\|WP_011054767.1\|1321084_1321813_-\|phage-antirepressor-KilAC-domain-containing-protein	gnl\|CDD\|226091	COG3561, COG3561, Phage anti-repressor protein [Transcription].	2.15147e-42
NZ_LS483437.1\|WP_015057910.1\|1330513_1331362_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	2.68212e-160
NZ_LS483437.1\|WP_076639348.1\|1334115_1336524_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	6.90158e-158
NZ_LS483437.1\|WP_031488520.1\|1328815_1329841_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_LS483437.1\|WP_002986896.1\|1324214_1325369_+\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.16705e-43
NZ_LS483437.1\|WP_076639345.1\|1326628_1327252_-\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.70169e-35

>NZ_LS483437.1|WP_002994841.1|1327264_1327975_-|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2
MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTITIFGKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGIHQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVASGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHMLLLKKVGGVLIIVMGILLMTGTLNNLAQLFG
>NZ_LS483437.1|WP_076639345.1|1326628_1327252_-|TlpA-family-protein-disulfide-reductase
MKKGLLVTTGLACLGLLTACSTQDNMAKKEITQDKMSMAAKKKDKMSTSKDKSMMADKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASWCSTCLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFKKWFQGTDYKDLPVLLDPDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH
>NZ_LS483437.1|WP_076639344.1|1325479_1326586_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKKVKSTKVDPNAPVDQKVIYLAGGCFWAVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIHQTGHAETVEVTYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADLAIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPVIDESKYPKPSATEIKEKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLFSSKDKFESGCGWPSFSRPISPDVIRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKDQGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE
>NZ_LS483437.1|WP_002986896.1|1324214_1325369_+|site-specific-integrase
MPISYLKISTPQRKERGKTMIEKYTKKDGTTAYRLRAYLGVDPVTGKQVRTTRQGFKTEREAKRAEVKLIDDFQRQGAWKSNDKTTFDDVAKLWFEQYQNTVKPSTFLVNQNYYKTILKPHLGQLQMTKITVMICQKFVNCLSRYSGYTLYLSLANRIFKFAVNLGIIDNNPMNKTLRSKCTYKNVDTLTKKYYTKEELNTFLRLVEAEETLEMRLIYRLLSYGGFRIGELIALKDTDFDFRNNTISITKTIAYTKEGWAVQSPKTKKSNRTISMDAETMSLAKLYIKQSIKPLHGSFKLFNFASDTVRKRLDRFILKHGLKRITPHGFRHTHASLLFEAGIPAKIAQERLGHAKIAITMDLYTHLSKKSKDNVADKLAELVAI
>NZ_LS483437.1|WP_002986895.1|1323574_1324096_+|hypothetical-protein
MKKIVYLFTLSVLIVCLGACTGGSKKDTTSKTPSSDTSKVSGDMSEKEYFDTLISKIDKVTTDNYKSDEYLFYDYKTILRDPKKYFSLKVRINNLKIIQISDKDKYTKMLANTPNGDLYMLFIETKRLETKLLETDNITINGRYLLSYEYTTTSGSENSVPLIYIDGYLLLDK
>NZ_LS483437.1|WP_002986894.1|1323183_1323564_+|hypothetical-protein
MMTPETVCQEKGIDLVYFDGRGTNIPGMFNKKHNVIAIDTYLDGIYKHKVIYHELGHREHTASYYKLNKEKAELQADRCMIHHLLKEELSYWDNMEDFNYIQFMEKYELTSIADEVMVKEEFKNLI
>NZ_LS483437.1|WP_011054768.1|1322810_1323170_+|helix-turn-helix-transcriptional-regulator
MTMFEVYSRIEALAKKRGVSLQKVATDIGLSENYIYNLKSKKTANTDPIEKIANYFNVSTDYLLGRTDNPKMAQDGHTSVAIDLKKDAEETFFFDGHELNDEDIDLITSILETRIKNRK
>NZ_LS483437.1|WP_002986891.1|1321823_1322015_-|hypothetical-protein
MPDNAIAIEKIKKYLLDNNLKQVDLAVTYGKEPQDVANILAGRKKDPASNRFVLKVISDLKIR
>NZ_LS483437.1|WP_011054767.1|1321084_1321813_-|phage-antirepressor-KilAC-domain-containing-protein
MNNLITVTLNENQEPIVSGRDLHQALEIKTQYTKWLERMSDYGFEENEDYVAISQKRLTAQGNQTEYTDHVLKLDMAKEIAMLQRNEKSKQVRKYFIQIEKDFNSPEKIMARALLMADKKVHKLEAQIEADRPKVLFADAVSASKSSCLIGELAKILKQNGVNIGQNKLFQWLRANGYLISRRGESWNQPTQKSMQLGLFELKKTAINHSDGHTTTNVTPKVTGKGQQYFINKFFNQEYLPV
>NZ_LS483437.1|WP_002986888.1|1320902_1321052_-|hypothetical-protein
MPEDLIKQLEAGSEFLAKTCLHSKIIITVDGIRLVETKEFHPVSGTLLD
>NZ_LS483437.1|WP_076639346.1|1328511_1328805_-|CRISPR-associated-endonuclease-Cas2
MMVLVTYDVNTETPAGRKRLRHVAKLCVDYGQRVQNSVFECSVTPAEFVDIKHRLTQIIDEKTDSTRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL
>NZ_LS483437.1|WP_031488520.1|1328815_1329841_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLYLTQEDFYVTKEGDNIVIKQEGKVLKRFPFRIIDGIVCFSYLGVSPALVKLCTENQINLSFHTPQGRFCGRYIGSTNGNVLLRREHYRLSDREESLEYAKRFILAKISNSRKYLLRFKRDHRQQIDTKLFEAVNDELIWALEMVQAADNKDSLRGIEGQAANQYFRIFNDLVLTDKKTFYFQGRSKRPPLDCVNALLSFGYSLLTFECQSALEAVGLDSYVGFFHTDRPGRASLALDLVEEFRSYIVDRFVFSLINKGQLQKKHFEVKENGSILMTENGRAIFIDLWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDLESYPPFMV
>NZ_LS483437.1|WP_003060901.1|1329837_1330512_-|CRISPR-associated-protein-Cas4
MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQVLHTKADNPYIKEKRKELLVSRAMPISSAELGLSGIMDVVEFYKDDQGVSLRGKRGKWLPKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLDCDINEGCLYYHSVNQRVIVPMTSALRQEVKELAAEMHEVYQSQMLPKAAYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMTSEEMDL
>NZ_LS483437.1|WP_015057910.1|1330513_1331362_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSIKRKIRNRLQDMGKSIFVQANERIEDDFRSLERRFSQHFTAKTPDKEIEEKANALWFDVRAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNNSGRSSDTMGTKHFVDYGVYVLKGSINAYFAEKTGFSQEDAEAIKEVLVSLFENDASSARPEGSMRVCEVFWFTHSSKLGNVSSARVFDLLEYHQSIEEKSTYDAYQIHLNQEKLAKYEAKGLTVEILEGL
>NZ_LS483437.1|WP_010922512.1|1333254_1333983_-|type-I-C-CRISPR-associated-protein-Cas5
MYRSRDFYVRVSGQRALFTNPATKGGSERSSYSVPTRQALNGIVDAIYYKPTFTNIVTEVKVINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFVWNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRECLGLVDDISQEEYETTVSYYNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVITFKAQSECDIVNTLSSYAFKAPEEIKSVNDECMEYDAMEKGEN
>NZ_LS483437.1|WP_076639348.1|1334115_1336524_-|CRISPR-associated-helicase/endonuclease-Cas3
MRMILAHYDCKKDKKQSLDEHLWHVACSSRQEASIIGQGDVLFLIGLYHDLGKADRTFQDKLLNNPNRHVDHSYAGAKYLYSIIGPRLKNRGVDKNERMTFNEMVGYVISAHHGMYDLCYYFDDAEYYGFNKFKNRINRDLDGYHYHEDIKGYALKLEKKLCDYGYKDLRELIDKAFDNYQQAMSSLNWQDKSEWDYYQSCMVRLYLSLLKNADILDTVNAYGLKISPMDKTERSFLKHSYLAAIEQKYASFGQPNNQLNTIRTEIAERVKERGKRDSNGIYRLDLPTGAGKTNLSMRYAFHQLVHHDKSRFFYITPFLSVLEQNASEIRKVTGDLGVLEHHSNVVKQANEDDDDKESLLSAYLSDSWDSQVVLTSMVQFFQTLFKTKSANLRRFSSLINSVVILDEVQSLPIEVTTLFNLTMNFLNKVMDTTIVLCTATQPAYDSSEIDHRICYGGNLGELAEIVELTIEERQIFSRTELRKFDDSDQKVHLTDVINLILGEENSVLAIFNTKKTVHNCYTMLKDMTDRPVYQLSTNMCAQHRLDLIAKIKTELQNNIPIICISTQLIEAGVDVDFHRVIRSYSGIDSIVQAAGRCNREGKRDKGQVTLVNLTNEEENVSRLTEIKAKKEATESILHKIGSPIDISTLNRDFFEYYYANNQGLMDYPLEDNLSIYDYLSLNIYQTANKKFKGKLKQAFKTAGAKMNLINNDMIGILVPYGEAEKKLAYLEELGMSHFLSAEDYQTIKSLLKELQPFTVNVRENDPLFETTKSYLNGQILVLTSEYYDTERGVKYDSASFYF
>NZ_LS483437.1|WP_076639349.1|1336677_1339326_-|valine--tRNA-ligase
MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGQGITRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFVDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATTRPETMFGDVAVAVNPEDPRYKDLIGKHVILPIVNKLIPIVGDEHADPEFGTGVVKITPAHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVNIEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDDRVDFYPPRFNDTFLQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSALWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDASWNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVTENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKILRLLHPIMPFVTEEIYAQYAQGSIVTVDYPVVRSAFENEAAHKGVESLKDLIRAVRNARAEVNVAPSKPITILVKTADSELEDFFNSNINYIKRFTNPEKLEISSAIAAPELAMTSIITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVVQKEKDKQADYQAKYDATQERIAEMKKIKS
>NZ_LS483437.1|WP_011888719.1|1339327_1339891_-|AAA-family-ATPase
MNLIIIGAQASGKMTIGQEVARQTGMTLFHNHDSIDFVLRFMPWSQESTALIERIRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVLFVELKTDIEERLKRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTHYQKINNTHLTAAETAQLIIQKMTHIKEN
>NZ_LS483437.1|WP_076639350.1|1340492_1340888_-|hypothetical-protein
MAKQKNRKKALKLEMKRNGLLKKAGQVFDKAVESVETAVDKTISAGKNLVEKGSQTVEKLTASKERLTLDEFAGQPVVAGIRSDLVETLYAEGIHSAQAFKEWTEKDLLALKGIGPATVKKLVENGASFKK
>NZ_LS483437.1|WP_002983750.1|1340905_1341160_-|DUF1912-family-protein
MSYEKEFLKDFEDWVKTQIQVNQLAMATSQEVAQEDGDERAKDAFIRYESKLDAYEFLLGKFDNYKNGKAFHDIPDELFGARHY

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448946	Streptococcus phage Javan456, complete genome	37158-37190	0	1.0
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448942	Streptococcus phage Javan448, complete genome	19074-19106	0	1.0
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448964	Streptococcus phage Javan502, complete genome	27931-27963	0	1.0
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448772	Streptococcus phage Javan483, complete genome	33441-33473	0	1.0
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448766	Streptococcus phage Javan465, complete genome	33553-33585	0	1.0
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448954	Streptococcus phage Javan476, complete genome	32464-32496	0	1.0
NZ_LS483437_3	3.3\|1328297\|35\|NZ_LS483437\|CRISPRCasFinder,CRT	1328297-1328331	35	NC_028700	Streptococcus phage T12, complete genome	7363-7397	0	1.0
NZ_LS483437_3	3.3\|1328297\|35\|NZ_LS483437\|CRISPRCasFinder,CRT	1328297-1328331	35	MK448793	Streptococcus phage Javan523, complete genome	7686-7720	0	1.0
NZ_LS483437_3	3.3\|1328297\|35\|NZ_LS483437\|CRISPRCasFinder,CRT	1328297-1328331	35	MK448950	Streptococcus phage Javan464, complete genome	7409-7443	0	1.0
NZ_LS483437_3	3.3\|1328297\|35\|NZ_LS483437\|CRISPRCasFinder,CRT	1328297-1328331	35	MK448960	Streptococcus phage Javan492, complete genome	7400-7434	1	0.971
NZ_LS483437_3	3.3\|1328297\|35\|NZ_LS483437\|CRISPRCasFinder,CRT	1328297-1328331	35	MK448762	Streptococcus phage Javan447, complete genome	7526-7560	1	0.971
NZ_LS483437_3	3.3\|1328297\|35\|NZ_LS483437\|CRISPRCasFinder,CRT	1328297-1328331	35	MK448795	Streptococcus phage Javan527, complete genome	13083-13117	1	0.971
NZ_LS483437_3	3.3\|1328297\|35\|NZ_LS483437\|CRISPRCasFinder,CRT	1328297-1328331	35	MK448954	Streptococcus phage Javan476, complete genome	7481-7515	1	0.971
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448946	Streptococcus phage Javan456, complete genome	37158-37191	1	0.971
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448942	Streptococcus phage Javan448, complete genome	19074-19107	1	0.971
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448964	Streptococcus phage Javan502, complete genome	27931-27964	1	0.971
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448772	Streptococcus phage Javan483, complete genome	33441-33474	1	0.971
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448766	Streptococcus phage Javan465, complete genome	33553-33586	1	0.971
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448954	Streptococcus phage Javan476, complete genome	32464-32497	1	0.971
NZ_LS483437_3	3.6\|1328297\|36\|NZ_LS483437\|PILER-CR	1328297-1328332	36	NC_028700	Streptococcus phage T12, complete genome	7362-7397	1	0.972
NZ_LS483437_3	3.6\|1328297\|36\|NZ_LS483437\|PILER-CR	1328297-1328332	36	MK448793	Streptococcus phage Javan523, complete genome	7685-7720	1	0.972
NZ_LS483437_3	3.6\|1328297\|36\|NZ_LS483437\|PILER-CR	1328297-1328332	36	MK448950	Streptococcus phage Javan464, complete genome	7408-7443	1	0.972
NZ_LS483437_3	3.1\|1328167\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328167-1328199	33	MK448791	Streptococcus phage Javan517, complete genome	14016-14048	2	0.939
NZ_LS483437_3	3.1\|1328167\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328167-1328199	33	NC_004587	Streptococcus prophage 315.4, complete genome	14111-14143	2	0.939
NZ_LS483437_3	3.1\|1328167\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328167-1328199	33	NC_003157	Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome	15381-15413	2	0.939
NZ_LS483437_3	3.1\|1328167\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328167-1328199	33	MK448977	Streptococcus phage Javan530, complete genome	14016-14048	2	0.939
NZ_LS483437_3	3.1\|1328167\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328167-1328199	33	MK448793	Streptococcus phage Javan523, complete genome	15458-15490	2	0.939
NZ_LS483437_3	3.1\|1328167\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328167-1328199	33	MK448788	Streptococcus phage Javan511, complete genome	14016-14048	2	0.939
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448793	Streptococcus phage Javan523, complete genome	34080-34112	2	0.939
NZ_LS483437_3	3.3\|1328297\|35\|NZ_LS483437\|CRISPRCasFinder,CRT	1328297-1328331	35	MK448790	Streptococcus phage Javan515, complete genome	7813-7847	2	0.943
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448793	Streptococcus phage Javan523, complete genome	34080-34113	2	0.941
NZ_LS483437_3	3.6\|1328297\|36\|NZ_LS483437\|PILER-CR	1328297-1328332	36	MK448960	Streptococcus phage Javan492, complete genome	7399-7434	2	0.944
NZ_LS483437_3	3.6\|1328297\|36\|NZ_LS483437\|PILER-CR	1328297-1328332	36	MK448762	Streptococcus phage Javan447, complete genome	7525-7560	2	0.944
NZ_LS483437_3	3.6\|1328297\|36\|NZ_LS483437\|PILER-CR	1328297-1328332	36	MK448795	Streptococcus phage Javan527, complete genome	13082-13117	2	0.944
NZ_LS483437_3	3.6\|1328297\|36\|NZ_LS483437\|PILER-CR	1328297-1328332	36	MK448954	Streptococcus phage Javan476, complete genome	7480-7515	2	0.944
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448763	Streptococcus phage Javan451, complete genome	28155-28187	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448777	Streptococcus phage Javan491, complete genome	28026-28058	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448767	Streptococcus phage Javan467, complete genome	28118-28150	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448771	Streptococcus phage Javan481, complete genome	27640-27672	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	NC_004586	Streptococcus pyogenes phage 315.3, complete genome	28223-28255	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448779	Streptococcus phage Javan497, complete genome	32393-32425	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448792	Streptococcus phage Javan521, complete genome	32644-32676	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448943	Streptococcus phage Javan450, complete genome	28118-28150	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448972	Streptococcus phage Javan520, complete genome	28296-28328	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448968	Streptococcus phage Javan512, complete genome	32393-32425	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	M19348	Streptococcus pyogenes phage H4489A hyaluronidase (hylP) and hypothetical protein genes, complete cds	1163-1195	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	NC_004584	Streptococcus prophage 315.1, complete genome	32237-32269	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448786	Streptococcus phage Javan509, complete genome	28118-28150	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448774	Streptococcus phage Javan487, complete genome	26475-26507	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448962	Streptococcus phage Javan496, complete genome	23793-23825	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448773	Streptococcus phage Javan485, complete genome	29247-29279	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448797	Streptococcus phage Javan531, complete genome	32393-32425	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448770	Streptococcus phage Javan477, complete genome	32644-32676	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448978	Streptococcus phage Javan532, complete genome	32131-32163	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448785	Streptococcus phage Javan507, complete genome	32132-32164	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448950	Streptococcus phage Javan464, complete genome	33336-33368	3	0.909
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	NC_004589	Streptococcus prophage 315.6, complete genome	32490-32522	3	0.909
NZ_LS483437_3	3.4\|1328167\|34\|NZ_LS483437\|PILER-CR	1328167-1328200	34	MK448791	Streptococcus phage Javan517, complete genome	14016-14049	3	0.912
NZ_LS483437_3	3.4\|1328167\|34\|NZ_LS483437\|PILER-CR	1328167-1328200	34	NC_004587	Streptococcus prophage 315.4, complete genome	14111-14144	3	0.912
NZ_LS483437_3	3.4\|1328167\|34\|NZ_LS483437\|PILER-CR	1328167-1328200	34	NC_003157	Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome	15381-15414	3	0.912
NZ_LS483437_3	3.4\|1328167\|34\|NZ_LS483437\|PILER-CR	1328167-1328200	34	MK448977	Streptococcus phage Javan530, complete genome	14016-14049	3	0.912
NZ_LS483437_3	3.4\|1328167\|34\|NZ_LS483437\|PILER-CR	1328167-1328200	34	MK448793	Streptococcus phage Javan523, complete genome	15458-15491	3	0.912
NZ_LS483437_3	3.4\|1328167\|34\|NZ_LS483437\|PILER-CR	1328167-1328200	34	MK448788	Streptococcus phage Javan511, complete genome	14016-14049	3	0.912
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448779	Streptococcus phage Javan497, complete genome	32393-32426	3	0.912
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448792	Streptococcus phage Javan521, complete genome	32644-32677	3	0.912
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448968	Streptococcus phage Javan512, complete genome	32393-32426	3	0.912
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	NC_004584	Streptococcus prophage 315.1, complete genome	32237-32270	3	0.912
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448962	Streptococcus phage Javan496, complete genome	23793-23826	3	0.912
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448797	Streptococcus phage Javan531, complete genome	32393-32426	3	0.912
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448770	Streptococcus phage Javan477, complete genome	32644-32677	3	0.912
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448978	Streptococcus phage Javan532, complete genome	32131-32164	3	0.912
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448785	Streptococcus phage Javan507, complete genome	32132-32165	3	0.912
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448950	Streptococcus phage Javan464, complete genome	33336-33369	3	0.912
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	NC_004589	Streptococcus prophage 315.6, complete genome	32490-32523	3	0.912
NZ_LS483437_3	3.6\|1328297\|36\|NZ_LS483437\|PILER-CR	1328297-1328332	36	MK448790	Streptococcus phage Javan515, complete genome	7812-7847	3	0.917
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448795	Streptococcus phage Javan527, complete genome	39171-39203	4	0.879
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MK448944	Streptococcus phage Javan452, complete genome	36205-36237	4	0.879
NZ_LS483437_3	3.3\|1328297\|35\|NZ_LS483437\|CRISPRCasFinder,CRT	1328297-1328331	35	MK448933	Streptococcus phage Javan420, complete genome	8681-8715	4	0.886
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448763	Streptococcus phage Javan451, complete genome	28155-28188	4	0.882
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448777	Streptococcus phage Javan491, complete genome	28026-28059	4	0.882
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448767	Streptococcus phage Javan467, complete genome	28118-28151	4	0.882
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448771	Streptococcus phage Javan481, complete genome	27640-27673	4	0.882
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	NC_004586	Streptococcus pyogenes phage 315.3, complete genome	28223-28256	4	0.882
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448943	Streptococcus phage Javan450, complete genome	28118-28151	4	0.882
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448972	Streptococcus phage Javan520, complete genome	28296-28329	4	0.882
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	M19348	Streptococcus pyogenes phage H4489A hyaluronidase (hylP) and hypothetical protein genes, complete cds	1163-1196	4	0.882
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448786	Streptococcus phage Javan509, complete genome	28118-28151	4	0.882
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448774	Streptococcus phage Javan487, complete genome	26475-26508	4	0.882
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448773	Streptococcus phage Javan485, complete genome	29247-29280	4	0.882
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448795	Streptococcus phage Javan527, complete genome	39171-39204	5	0.853
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MK448944	Streptococcus phage Javan452, complete genome	36205-36238	5	0.853
NZ_LS483437_3	3.6\|1328297\|36\|NZ_LS483437\|PILER-CR	1328297-1328332	36	MK448933	Streptococcus phage Javan420, complete genome	8680-8715	5	0.861
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MT774404	CrAssphage cr114_1, complete genome	58153-58185	7	0.788
NZ_LS483437_3	3.2\|1328232\|33\|NZ_LS483437\|CRISPRCasFinder,CRT	1328232-1328264	33	MN582077	Podoviridae sp. ctLUJ1, complete genome	31322-31354	8	0.758
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MT774404	CrAssphage cr114_1, complete genome	58153-58186	8	0.765
NZ_LS483437_3	3.5\|1328232\|34\|NZ_LS483437\|PILER-CR	1328232-1328265	34	MN582077	Podoviridae sp. ctLUJ1, complete genome	31322-31355	9	0.735

1. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448946 (Streptococcus phage Javan456, complete genome) position: , mismatch: 0, identity: 1.0

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
gaaaaacatgctgcgactaaaaaatacgtagat	Protospacer
*********************************

2. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448942 (Streptococcus phage Javan448, complete genome) position: , mismatch: 0, identity: 1.0

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
gaaaaacatgctgcgactaaaaaatacgtagat	Protospacer
*********************************

3. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 0, identity: 1.0

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
gaaaaacatgctgcgactaaaaaatacgtagat	Protospacer
*********************************

4. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448772 (Streptococcus phage Javan483, complete genome) position: , mismatch: 0, identity: 1.0

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
gaaaaacatgctgcgactaaaaaatacgtagat	Protospacer
*********************************

5. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448766 (Streptococcus phage Javan465, complete genome) position: , mismatch: 0, identity: 1.0

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
gaaaaacatgctgcgactaaaaaatacgtagat	Protospacer
*********************************

6. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 0, identity: 1.0

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
gaaaaacatgctgcgactaaaaaatacgtagat	Protospacer
*********************************

7. spacer 3.3|1328297|35|NZ_LS483437|CRISPRCasFinder,CRT matches to NC_028700 (Streptococcus phage T12, complete genome) position: , mismatch: 0, identity: 1.0

tctccatgctcttaattcttcaattttctttgttc	CRISPR spacer
tctccatgctcttaattcttcaattttctttgttc	Protospacer
***********************************

8. spacer 3.3|1328297|35|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 0, identity: 1.0

tctccatgctcttaattcttcaattttctttgttc	CRISPR spacer
tctccatgctcttaattcttcaattttctttgttc	Protospacer
***********************************

9. spacer 3.3|1328297|35|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 0, identity: 1.0

tctccatgctcttaattcttcaattttctttgttc	CRISPR spacer
tctccatgctcttaattcttcaattttctttgttc	Protospacer
***********************************

10. spacer 3.3|1328297|35|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448960 (Streptococcus phage Javan492, complete genome) position: , mismatch: 1, identity: 0.971

tctccatgctcttaattcttcaattttctttgttc	CRISPR spacer
tctccatgctctcaattcttcaattttctttgttc	Protospacer
************.**********************

11. spacer 3.3|1328297|35|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448762 (Streptococcus phage Javan447, complete genome) position: , mismatch: 1, identity: 0.971

tctccatgctcttaattcttcaattttctttgttc	CRISPR spacer
tctccatgctctcaattcttcaattttctttgttc	Protospacer
************.**********************

12. spacer 3.3|1328297|35|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 1, identity: 0.971

tctccatgctcttaattcttcaattttctttgttc	CRISPR spacer
tctccatgctctcaattcttcaattttctttgttc	Protospacer
************.**********************

13. spacer 3.3|1328297|35|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 1, identity: 0.971

tctccatgctcttaattcttcaattttctttgttc	CRISPR spacer
tctccatgctctcaattcttcaattttctttgttc	Protospacer
************.**********************

14. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448946 (Streptococcus phage Javan456, complete genome) position: , mismatch: 1, identity: 0.971

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
gaaaaacatgctgcgactaaaaaatacgtagatg	Protospacer
*********************************.

15. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448942 (Streptococcus phage Javan448, complete genome) position: , mismatch: 1, identity: 0.971

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
gaaaaacatgctgcgactaaaaaatacgtagatg	Protospacer
*********************************.

16. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 1, identity: 0.971

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
gaaaaacatgctgcgactaaaaaatacgtagatg	Protospacer
*********************************.

17. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448772 (Streptococcus phage Javan483, complete genome) position: , mismatch: 1, identity: 0.971

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
gaaaaacatgctgcgactaaaaaatacgtagatg	Protospacer
*********************************.

18. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448766 (Streptococcus phage Javan465, complete genome) position: , mismatch: 1, identity: 0.971

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
gaaaaacatgctgcgactaaaaaatacgtagatg	Protospacer
*********************************.

19. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 1, identity: 0.971

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
gaaaaacatgctgcgactaaaaaatacgtagatg	Protospacer
*********************************.

20. spacer 3.6|1328297|36|NZ_LS483437|PILER-CR matches to NC_028700 (Streptococcus phage T12, complete genome) position: , mismatch: 1, identity: 0.972

tctccatgctcttaattcttcaattttctttgttca	CRISPR spacer
tctccatgctcttaattcttcaattttctttgttcg	Protospacer
***********************************.

21. spacer 3.6|1328297|36|NZ_LS483437|PILER-CR matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 1, identity: 0.972

tctccatgctcttaattcttcaattttctttgttca	CRISPR spacer
tctccatgctcttaattcttcaattttctttgttcg	Protospacer
***********************************.

22. spacer 3.6|1328297|36|NZ_LS483437|PILER-CR matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 1, identity: 0.972

tctccatgctcttaattcttcaattttctttgttca	CRISPR spacer
tctccatgctcttaattcttcaattttctttgttcg	Protospacer
***********************************.

23. spacer 3.1|1328167|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448791 (Streptococcus phage Javan517, complete genome) position: , mismatch: 2, identity: 0.939

gctgactttgatgtcggtgcagaacacgttgga	CRISPR spacer
gctgactttgatgtcggcgcagaacacgttaga	Protospacer
*****************.************.**

24. spacer 3.1|1328167|33|NZ_LS483437|CRISPRCasFinder,CRT matches to NC_004587 (Streptococcus prophage 315.4, complete genome) position: , mismatch: 2, identity: 0.939

gctgactttgatgtcggtgcagaacacgttgga	CRISPR spacer
gctgactttgatgtcggcgcagaacacgttaga	Protospacer
*****************.************.**

25. spacer 3.1|1328167|33|NZ_LS483437|CRISPRCasFinder,CRT matches to NC_003157 (Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome) position: , mismatch: 2, identity: 0.939

gctgactttgatgtcggtgcagaacacgttgga	CRISPR spacer
gctgactttgatgtcggcgcagaacacgttaga	Protospacer
*****************.************.**

26. spacer 3.1|1328167|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448977 (Streptococcus phage Javan530, complete genome) position: , mismatch: 2, identity: 0.939

gctgactttgatgtcggtgcagaacacgttgga	CRISPR spacer
gctgactttgatgtcggcgcagaacacgttaga	Protospacer
*****************.************.**

27. spacer 3.1|1328167|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 2, identity: 0.939

gctgactttgatgtcggtgcagaacacgttgga	CRISPR spacer
gctgactttgatgtcggcgcagaacacgttaga	Protospacer
*****************.************.**

28. spacer 3.1|1328167|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448788 (Streptococcus phage Javan511, complete genome) position: , mismatch: 2, identity: 0.939

gctgactttgatgtcggtgcagaacacgttgga	CRISPR spacer
gctgactttgatgtcggcgcagaacacgttaga	Protospacer
*****************.************.**

29. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 2, identity: 0.939

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
gaaaaacatgctgcgactaaagattacgtagat	Protospacer
*********************.* *********

30. spacer 3.3|1328297|35|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448790 (Streptococcus phage Javan515, complete genome) position: , mismatch: 2, identity: 0.943

tctccatgctcttaattcttcaattttctttgttc	CRISPR spacer
tctccacgctctcaattcttcaattttctttgttc	Protospacer
******.*****.**********************

31. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 2, identity: 0.941

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
gaaaaacatgctgcgactaaagattacgtagata	Protospacer
*********************.* **********

32. spacer 3.6|1328297|36|NZ_LS483437|PILER-CR matches to MK448960 (Streptococcus phage Javan492, complete genome) position: , mismatch: 2, identity: 0.944

tctccatgctcttaattcttcaattttctttgttca	CRISPR spacer
tctccatgctctcaattcttcaattttctttgttcg	Protospacer
************.**********************.

33. spacer 3.6|1328297|36|NZ_LS483437|PILER-CR matches to MK448762 (Streptococcus phage Javan447, complete genome) position: , mismatch: 2, identity: 0.944

tctccatgctcttaattcttcaattttctttgttca	CRISPR spacer
tctccatgctctcaattcttcaattttctttgttcg	Protospacer
************.**********************.

34. spacer 3.6|1328297|36|NZ_LS483437|PILER-CR matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 2, identity: 0.944

tctccatgctcttaattcttcaattttctttgttca	CRISPR spacer
tctccatgctctcaattcttcaattttctttgttcg	Protospacer
************.**********************.

35. spacer 3.6|1328297|36|NZ_LS483437|PILER-CR matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 2, identity: 0.944

tctccatgctcttaattcttcaattttctttgttca	CRISPR spacer
tctccatgctctcaattcttcaattttctttgttcg	Protospacer
************.**********************.

36. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
agcaaacatgctgcgactaaaaaatacgtagat	Protospacer
.. ******************************

37. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448777 (Streptococcus phage Javan491, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
agcaaacatgctgcgactaaaaaatacgtagat	Protospacer
.. ******************************

38. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448767 (Streptococcus phage Javan467, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagat	Protospacer
*.*******************.* *********

39. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagat	Protospacer
*.*******************.* *********

40. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to NC_004586 (Streptococcus pyogenes phage 315.3, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagat	Protospacer
*.*******************.* *********

41. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448779 (Streptococcus phage Javan497, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagat	Protospacer
*.*******************.* *********

42. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448792 (Streptococcus phage Javan521, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagat	Protospacer
*.*******************.* *********

43. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448943 (Streptococcus phage Javan450, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagat	Protospacer
*.*******************.* *********

44. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagat	Protospacer
*.*******************.* *********

45. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448968 (Streptococcus phage Javan512, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagat	Protospacer
*.*******************.* *********

46. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to M19348 (Streptococcus pyogenes phage H4489A hyaluronidase (hylP) and hypothetical protein genes, complete cds) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagat	Protospacer
*.*******************.* *********

47. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to NC_004584 (Streptococcus prophage 315.1, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagat	Protospacer
*.*******************.* *********

48. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448786 (Streptococcus phage Javan509, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagat	Protospacer
*.*******************.* *********

49. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagat	Protospacer
*.*******************.* *********

50. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448962 (Streptococcus phage Javan496, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagat	Protospacer
*.*******************.* *********

51. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagat	Protospacer
*.*******************.* *********

52. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448797 (Streptococcus phage Javan531, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagat	Protospacer
*.*******************.* *********

53. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448770 (Streptococcus phage Javan477, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagat	Protospacer
*.*******************.* *********

54. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448978 (Streptococcus phage Javan532, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagat	Protospacer
*.*******************.* *********

55. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448785 (Streptococcus phage Javan507, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagat	Protospacer
*.*******************.* *********

56. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagat	Protospacer
*.*******************.* *********

57. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to NC_004589 (Streptococcus prophage 315.6, complete genome) position: , mismatch: 3, identity: 0.909

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagat	Protospacer
*.*******************.* *********

58. spacer 3.4|1328167|34|NZ_LS483437|PILER-CR matches to MK448791 (Streptococcus phage Javan517, complete genome) position: , mismatch: 3, identity: 0.912

gctgactttgatgtcggtgcagaacacgttggaa	CRISPR spacer
gctgactttgatgtcggcgcagaacacgttagag	Protospacer
*****************.************.**.

59. spacer 3.4|1328167|34|NZ_LS483437|PILER-CR matches to NC_004587 (Streptococcus prophage 315.4, complete genome) position: , mismatch: 3, identity: 0.912

gctgactttgatgtcggtgcagaacacgttggaa	CRISPR spacer
gctgactttgatgtcggcgcagaacacgttagag	Protospacer
*****************.************.**.

60. spacer 3.4|1328167|34|NZ_LS483437|PILER-CR matches to NC_003157 (Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome) position: , mismatch: 3, identity: 0.912

gctgactttgatgtcggtgcagaacacgttggaa	CRISPR spacer
gctgactttgatgtcggcgcagaacacgttagag	Protospacer
*****************.************.**.

61. spacer 3.4|1328167|34|NZ_LS483437|PILER-CR matches to MK448977 (Streptococcus phage Javan530, complete genome) position: , mismatch: 3, identity: 0.912

gctgactttgatgtcggtgcagaacacgttggaa	CRISPR spacer
gctgactttgatgtcggcgcagaacacgttagag	Protospacer
*****************.************.**.

62. spacer 3.4|1328167|34|NZ_LS483437|PILER-CR matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 3, identity: 0.912

gctgactttgatgtcggtgcagaacacgttggaa	CRISPR spacer
gctgactttgatgtcggcgcagaacacgttagag	Protospacer
*****************.************.**.

63. spacer 3.4|1328167|34|NZ_LS483437|PILER-CR matches to MK448788 (Streptococcus phage Javan511, complete genome) position: , mismatch: 3, identity: 0.912

gctgactttgatgtcggtgcagaacacgttggaa	CRISPR spacer
gctgactttgatgtcggcgcagaacacgttagag	Protospacer
*****************.************.**.

64. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448779 (Streptococcus phage Javan497, complete genome) position: , mismatch: 3, identity: 0.912

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagata	Protospacer
*.*******************.* **********

65. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448792 (Streptococcus phage Javan521, complete genome) position: , mismatch: 3, identity: 0.912

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagata	Protospacer
*.*******************.* **********

66. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448968 (Streptococcus phage Javan512, complete genome) position: , mismatch: 3, identity: 0.912

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagata	Protospacer
*.*******************.* **********

67. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to NC_004584 (Streptococcus prophage 315.1, complete genome) position: , mismatch: 3, identity: 0.912

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagata	Protospacer
*.*******************.* **********

68. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448962 (Streptococcus phage Javan496, complete genome) position: , mismatch: 3, identity: 0.912

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagata	Protospacer
*.*******************.* **********

69. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448797 (Streptococcus phage Javan531, complete genome) position: , mismatch: 3, identity: 0.912

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagata	Protospacer
*.*******************.* **********

70. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448770 (Streptococcus phage Javan477, complete genome) position: , mismatch: 3, identity: 0.912

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagata	Protospacer
*.*******************.* **********

71. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448978 (Streptococcus phage Javan532, complete genome) position: , mismatch: 3, identity: 0.912

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagata	Protospacer
*.*******************.* **********

72. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448785 (Streptococcus phage Javan507, complete genome) position: , mismatch: 3, identity: 0.912

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagata	Protospacer
*.*******************.* **********

73. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 3, identity: 0.912

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagata	Protospacer
*.*******************.* **********

74. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to NC_004589 (Streptococcus prophage 315.6, complete genome) position: , mismatch: 3, identity: 0.912

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagata	Protospacer
*.*******************.* **********

75. spacer 3.6|1328297|36|NZ_LS483437|PILER-CR matches to MK448790 (Streptococcus phage Javan515, complete genome) position: , mismatch: 3, identity: 0.917

tctccatgctcttaattcttcaattttctttgttca	CRISPR spacer
tctccacgctctcaattcttcaattttctttgttcg	Protospacer
******.*****.**********************.

76. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 4, identity: 0.879

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
aacgaacatgctgtgactaaaaaatacgtagat	Protospacer
.* .*********.*******************

77. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 4, identity: 0.879

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
aacgaacatgctgtgactaaaaaatacgtagat	Protospacer
.* .*********.*******************

78. spacer 3.3|1328297|35|NZ_LS483437|CRISPRCasFinder,CRT matches to MK448933 (Streptococcus phage Javan420, complete genome) position: , mismatch: 4, identity: 0.886

tctccatgctcttaattcttcaattttctttgttc	CRISPR spacer
cctccatgctcttaattcttcaatcttctttttcc	Protospacer
.***********************.****** *.*

79. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 4, identity: 0.882

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
agcaaacatgctgcgactaaaaaatacgtagatg	Protospacer
.. ******************************.

80. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448777 (Streptococcus phage Javan491, complete genome) position: , mismatch: 4, identity: 0.882

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
agcaaacatgctgcgactaaaaaatacgtagatg	Protospacer
.. ******************************.

81. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448767 (Streptococcus phage Javan467, complete genome) position: , mismatch: 4, identity: 0.882

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagatg	Protospacer
*.*******************.* *********.

82. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 4, identity: 0.882

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagatg	Protospacer
*.*******************.* *********.

83. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to NC_004586 (Streptococcus pyogenes phage 315.3, complete genome) position: , mismatch: 4, identity: 0.882

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagatg	Protospacer
*.*******************.* *********.

84. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448943 (Streptococcus phage Javan450, complete genome) position: , mismatch: 4, identity: 0.882

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagatg	Protospacer
*.*******************.* *********.

85. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 4, identity: 0.882

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagatg	Protospacer
*.*******************.* *********.

86. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to M19348 (Streptococcus pyogenes phage H4489A hyaluronidase (hylP) and hypothetical protein genes, complete cds) position: , mismatch: 4, identity: 0.882

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagatg	Protospacer
*.*******************.* *********.

87. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448786 (Streptococcus phage Javan509, complete genome) position: , mismatch: 4, identity: 0.882

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagatg	Protospacer
*.*******************.* *********.

88. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 4, identity: 0.882

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagatg	Protospacer
*.*******************.* *********.

89. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 4, identity: 0.882

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
ggaaaacatgctgcgactaaagattacgtagatg	Protospacer
*.*******************.* *********.

90. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 5, identity: 0.853

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
aacgaacatgctgtgactaaaaaatacgtagatg	Protospacer
.* .*********.*******************.

91. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 5, identity: 0.853

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
aacgaacatgctgtgactaaaaaatacgtagatg	Protospacer
.* .*********.*******************.

92. spacer 3.6|1328297|36|NZ_LS483437|PILER-CR matches to MK448933 (Streptococcus phage Javan420, complete genome) position: , mismatch: 5, identity: 0.861

tctccatgctcttaattcttcaattttctttgttca	CRISPR spacer
cctccatgctcttaattcttcaatcttctttttccg	Protospacer
.***********************.****** *.*.

93. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MT774404 (CrAssphage cr114_1, complete genome) position: , mismatch: 7, identity: 0.788

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
aagtataatcctgctactaaaaaatacgtagat	Protospacer
.*. *  ** **** ******************

94. spacer 3.2|1328232|33|NZ_LS483437|CRISPRCasFinder,CRT matches to MN582077 (Podoviridae sp. ctLUJ1, complete genome) position: , mismatch: 8, identity: 0.758

gaaaaacatgctgcgactaaaaaatacgtagat	CRISPR spacer
gtactcactgctgcgactaaaaaataaggagat	Protospacer
* *     ****************** * ****

95. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MT774404 (CrAssphage cr114_1, complete genome) position: , mismatch: 8, identity: 0.765

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
aagtataatcctgctactaaaaaatacgtagatg	Protospacer
.*. *  ** **** ******************.

96. spacer 3.5|1328232|34|NZ_LS483437|PILER-CR matches to MN582077 (Podoviridae sp. ctLUJ1, complete genome) position: , mismatch: 9, identity: 0.735

gaaaaacatgctgcgactaaaaaatacgtagata	CRISPR spacer
gtactcactgctgcgactaaaaaataaggagatg	Protospacer
* *     ****************** * ****.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

36640 : 49027

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087486699.1\|36640_40366_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	9.2e-41	27.4
WP_087486700.1\|40599_42054_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	8.3e-54	33.5
WP_032464121.1\|42081_43104_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	4.0e-63	41.4
WP_002986700.1\|43271_43826_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.4e-25	36.1
WP_076639719.1\|44009_45557_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	4.4e-45	52.4
WP_076639718.1\|45614_46739_-	SH3 domain-containing protein	F8HGP2	Streptococcus_phage	7.7e-07	28.6
WP_076639717.1\|46991_48257_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_002986689.1\|48535_49027_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.9e-18	42.3

DBSCAN-SWA_2

266484 : 293587

Shigella_phage(20.0%)

protease,transposase,integrase

attL 258077:258092|attR 304789:304804

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
258077:258092	attL	NA	NA	NA	NA
WP_077707078.1\|266484_266574_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_080497430.1\|267008_267149_-\|transposase	transposase	NA	NA	NA	NA
WP_079890479.1\|267188_267386_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	U5P429	Shigella_phage	1.1e-09	47.5
WP_076639623.1\|267461_267758_-\|transposase	IS3 family transposase	A0A0C5AEB1	Paenibacillus_phage	9.3e-05	33.3
WP_020904871.1\|267790_268084_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_011888599.1\|273770_274352_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_002991099.1\|274932_275460_+	YqeG family HAD IIIA-type phosphatase	NA	NA	NA	NA
WP_011184178.1\|275459_276578_+	ribosome biogenesis GTPase YqeH	NA	NA	NA	NA
WP_030127134.1\|276602_276911_+	ribosome assembly RNA-binding protein YhbY	NA	NA	NA	NA
WP_002991091.1\|276979_277612_+	nicotinate-nucleotide adenylyltransferase	G3MA22	Bacillus_virus	6.2e-22	34.8
WP_002985989.1\|277608_278202_+	HD domain-containing protein	NA	NA	NA	NA
WP_015055915.1\|278225_278579_+	ribosome silencing factor	NA	NA	NA	NA
WP_021775484.1\|278626_279370_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_011184181.1\|279623_280730_+	nucleotidyltransferase	NA	NA	NA	NA
WP_002985979.1\|281211_281928_+	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_020904902.1\|282130_282973_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_011054193.1\|283299_284145_+	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_020904903.1\|284394_285459_+	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.7e-29	36.0
WP_002991836.1\|285459_286152_+	ABC transporter permease	NA	NA	NA	NA
WP_032464179.1\|286205_287576_-	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_002991840.1\|287809_289024_+	serine/threonine transporter SstT	NA	NA	NA	NA
WP_002991064.1\|289078_289753_-	TrkA family potassium uptake protein	NA	NA	NA	NA
WP_076639620.1\|289762_291154_-	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_023078972.1\|291223_291937_-	16S rRNA (guanine(527)-N(7))-methyltransferase RsmG	NA	NA	NA	NA
WP_014407314.1\|292086_292644_+	LemA family protein	A0A1X9IGG1	Lactococcus_phage	6.2e-10	28.8
WP_014407315.1\|292690_293587_+\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
304789:304804	attR	NA	NA	NA	NA

DBSCAN-SWA_3

512279 : 616117

116

Streptococcus_phage(59.15%)

capsid,protease,portal,tail,terminase,head,holin,integrase,tRNA

attL 518983:519000|attR 590552:590569

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021775322.1\|512279_513404_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_096466706.1\|513472_514570_+	peptide chain release factor 2	NA	NA	NA	NA
WP_002985455.1\|514589_515282_+	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	1.0e-30	35.6
WP_002990498.1\|515274_516204_+	ABC transporter permease	NA	NA	NA	NA
WP_011284638.1\|516512_517211_-	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	1.0e-78	62.9
WP_002990495.1\|517378_518143_+	(S)-acetoin forming diacetyl reductase	NA	NA	NA	NA
WP_076639550.1\|518250_520752_+	bifunctional DnaQ family exonuclease/ATP-dependent helicase	A0A1X9I5C8	Streptococcus_phage	2.8e-203	48.0
518983:519000	attL	NA	NA	NA	NA
WP_002985439.1\|521088_522282_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_002985437.1\|522302_523649_+\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.1e-55	30.8
WP_030127588.1\|524062_524953_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	5.1e-06	29.5
WP_020905024.1\|524949_525927_+	YvcK family protein	A1IMD5	Streptococcus_phage	9.6e-139	74.2
WP_002985428.1\|525923_526835_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.3e-105	64.7
WP_010922052.1\|527011_528427_-	recombinase family protein	A5GZ62	Lactococcus_phage	2.3e-109	47.0
WP_011106738.1\|528546_528852_-	membrane protein	NA	NA	NA	NA
WP_030127591.1\|528861_529650_-	phage repressor protein	A0A1S5SD15	Streptococcus_phage	2.0e-86	63.0
WP_021340643.1\|530019_530169_+	hypothetical protein	J7KH12	Streptococcus_phage	4.3e-19	91.8
WP_014635530.1\|530154_530370_-	hypothetical protein	J7KBX0	Streptococcus_phage	8.8e-29	97.1
WP_021340638.1\|530428_530587_+	hypothetical protein	J7KH24	Streptococcus_phage	5.8e-22	92.3
WP_001008979.1\|530685_531327_-	hypothetical protein	J7KJ31	Streptococcus_phage	1.5e-116	100.0
WP_014411882.1\|531419_531659_+	helix-turn-helix transcriptional regulator	A0A097PBE6	Streptococcus_pyogenes_phage	1.4e-35	98.7
WP_023610918.1\|531669_532431_+	phage antirepressor KilAC domain-containing protein	A0A0C5AEJ9	Bacteriophage	3.6e-85	61.9
WP_011889039.1\|532571_532754_-	hypothetical protein	NA	NA	NA	NA
WP_076639549.1\|532840_532978_+	hypothetical protein	NA	NA	NA	NA
WP_032465394.1\|532979_533165_+	hypothetical protein	Q938N3	Temperate_phage	3.1e-22	91.8
WP_011017564.1\|533683_534070_+	DnaD domain-containing protein	Q938N2	Temperate_phage	8.1e-25	51.9
WP_010922205.1\|534050_534284_+	hypothetical protein	Q938N1	Temperate_phage	2.8e-36	96.1
WP_002988354.1\|534280_534421_+	hypothetical protein	A0A1X9I6Y1	Streptococcus_phage	3.4e-05	54.5
WP_002988357.1\|534429_534636_+	hypothetical protein	NA	NA	NA	NA
WP_011528796.1\|534691_535021_+	hypothetical protein	J7KGX3	Streptococcus_phage	7.1e-46	84.4
WP_011054700.1\|535023_535950_+	recombinase RecT	M1NRN6	Streptococcus_phage	1.2e-90	71.8
WP_000594115.1\|535946_536147_+	hypothetical protein	NA	NA	NA	NA
WP_076639548.1\|536139_536937_+	PD-(D/E)XK nuclease-like domain-containing protein	J7KGZ1	Streptococcus_phage	5.2e-127	82.3
WP_030127594.1\|537113_537455_+	hypothetical protein	M1NS23	Streptococcus_phage	1.4e-12	39.6
WP_029714370.1\|537451_537964_+	hypothetical protein	Q708P9	Streptococcus_phage	3.4e-63	74.4
WP_011017567.1\|537950_538148_+	hypothetical protein	A3F626	Streptococcus_phage	9.9e-11	86.5
WP_011017568.1\|538141_538426_+	DUF3310 domain-containing protein	A0A1P8VVP5	Streptococcus_phage	7.0e-50	100.0
WP_002987593.1\|538422_538692_+	hypothetical protein	A0A1P8VVR6	Streptococcus_phage	3.1e-47	100.0
WP_011017569.1\|538701_539115_+	hypothetical protein	Q938M1	Temperate_phage	6.4e-36	65.2
WP_030127595.1\|539111_539396_+	hypothetical protein	A3F628	Streptococcus_phage	7.0e-42	95.7
WP_011017571.1\|539399_539882_+	class I SAM-dependent methyltransferase	A0A097PAU8	Streptococcus_pyogenes_phage	9.6e-92	98.8
WP_076639547.1\|540072_540474_+	hypothetical protein	NA	NA	NA	NA
WP_011054572.1\|540473_541109_+	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	2.2e-88	68.9
WP_011017866.1\|541382_541823_+	ArpU family transcriptional regulator	Q938L8	Temperate_phage	5.0e-79	100.0
WP_030127683.1\|542377_543289_+	DNA adenine methylase	A0A126HDT5	Lactococcus_phage	4.3e-101	64.5
WP_002987543.1\|543414_543792_-	type II toxin-antitoxin system HicB family antitoxin	I3NLB2	Bifidobacterium_phage	3.3e-15	44.0
WP_001132273.1\|543843_544029_-	type II toxin-antitoxin system HicA family toxin	D6PSW1	Lactobacillus_phage	1.7e-09	54.0
WP_002985371.1\|544772_545240_+\|terminase	phage terminase small subunit P27 family	J7KC46	Streptococcus_phage	3.9e-82	98.7
WP_002985368.1\|545242_545473_+	hypothetical protein	NA	NA	NA	NA
WP_024623442.1\|545476_547231_+	amino acid transporter	J7KKD1	Streptococcus_phage	0.0e+00	96.1
WP_021299470.1\|547227_547398_+	hypothetical protein	J7KK43	Streptococcus_phage	3.9e-08	60.4
WP_002985363.1\|547390_547615_+	hypothetical protein	Q938K9	Temperate_phage	3.6e-17	61.4
WP_011017578.1\|547648_548869_+\|portal	phage portal protein	J7KDU3	Streptococcus_phage	6.9e-187	81.9
WP_011017579.1\|548846_549512_+\|protease	Clp protease ClpP	M1Q115	Streptococcus_phage	3.5e-92	78.1
WP_011017580.1\|549536_550724_+\|capsid	phage major capsid protein	J7KJ82	Streptococcus_phage	1.3e-158	74.7
WP_011017581.1\|550868_551171_+\|head,tail	phage head-tail connector protein	J7KC36	Streptococcus_phage	1.3e-41	88.8
WP_011017582.1\|551167_551515_+\|head	phage head closure protein	J7KJ42	Streptococcus_phage	2.9e-50	88.2
WP_011527557.1\|551511_551889_+	HK97 gp10 family phage protein	J7KDM3	Streptococcus_phage	1.8e-45	72.8
WP_011017584.1\|551885_552311_+	hypothetical protein	J7KBZ9	Streptococcus_phage	7.2e-67	84.4
WP_011017585.1\|552326_552935_+	hypothetical protein	J7KKC8	Streptococcus_phage	6.7e-74	71.9
WP_011017586.1\|552987_553314_+	hypothetical protein	J7KK85	Streptococcus_phage	8.3e-39	75.0
WP_021299462.1\|553361_553511_+	hypothetical protein	J7KBS0	Streptococcus_phage	1.7e-15	85.7
WP_030127684.1\|553523_557447_+\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	2.5e-238	48.3
WP_011527559.1\|557446_558154_+\|tail	phage tail family protein	Q938K2	Temperate_phage	6.8e-94	71.9
WP_076639342.1\|558150_560298_+\|tail	phage tail protein	Q938K1	Temperate_phage	0.0e+00	93.1
WP_063808246.1\|560297_561572_+	collagen-like protein	A3F657	Streptococcus_phage	2.1e-21	39.9
WP_063808247.1\|561574_562222_+	hypothetical protein	A3F658	Streptococcus_phage	1.4e-50	47.0
WP_076639341.1\|562232_564269_+	gp58-like family protein	Q938J9	Temperate_phage	8.3e-169	69.5
WP_002983467.1\|564280_564712_+	DUF1617 family protein	Q938J8	Temperate_phage	1.3e-63	89.5
WP_011017592.1\|564714_565332_+	DUF1366 domain-containing protein	Q938J7	Temperate_phage	5.0e-77	89.3
WP_002987582.1\|565341_565617_+	hypothetical protein	A7J2B2	Streptococcus_phage	2.6e-41	100.0
WP_000609113.1\|565613_565841_+\|holin	phage holin	A7J2B3	Streptococcus_phage	5.8e-31	98.7
WP_002985329.1\|565956_567162_+	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	1.6e-204	83.3
WP_002985327.1\|567229_567937_-	streptococcal pyrogenic exotoxin SpeC	A0A097PAT7	Streptococcus_pyogenes_phage	3.9e-09	27.1
WP_002985324.1\|568047_568806_-	DNase Mf2	NA	NA	NA	NA
WP_063723270.1\|569117_570536_+	C69 family dipeptidase	NA	NA	NA	NA
WP_076639340.1\|570687_572235_+	zinc ABC transporter substrate-binding protein AdcA	NA	NA	NA	NA
WP_002990479.1\|572382_573105_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_076639339.1\|573124_574324_+	SIS domain-containing protein	NA	NA	NA	NA
WP_002985307.1\|574420_574681_-	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_076639338.1\|574795_575737_-	bifunctional oligoribonuclease/PAP phosphatase NrnA	NA	NA	NA	NA
WP_032460256.1\|576130_576580_+	flavodoxin	NA	NA	NA	NA
WP_063631291.1\|576755_577040_+	chorismate mutase	NA	NA	NA	NA
WP_076639337.1\|577032_578295_+	voltage-gated chloride channel family protein	A0A1X9I5Z9	Streptococcus_phage	1.1e-94	51.0
WP_002985298.1\|578409_578757_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_087486710.1\|579118_579412_-\|integrase	tyrosine-type recombinase/integrase	A0A141DZH6	Streptococcus_phage	1.2e-09	45.9
WP_002985295.1\|579771_580341_+	hydrolase	NA	NA	NA	NA
WP_011017600.1\|580341_582294_+	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	8.9e-144	46.2
WP_002990455.1\|582661_584386_+	septation ring formation regulator EzrA	NA	NA	NA	NA
WP_002990451.1\|584517_584976_-	YueI family protein	W6LLD2	Streptococcus_phage	1.8e-18	39.1
WP_002985288.1\|585208_586516_+	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	1.2e-240	96.6
WP_002985285.1\|587190_587352_+	TOMM family cytolysin streptolysin S	NA	NA	NA	NA
WP_002985278.1\|587573_588524_+	streptolysin S biosynthesis dehydrogenase SagB	NA	NA	NA	NA
WP_002985275.1\|588520_589579_+	streptolysin associated protein SagC	NA	NA	NA	NA
WP_002990434.1\|589598_590957_+	YcaO-like family protein	NA	NA	NA	NA
590552:590569	attR	NA	NA	NA	NA
WP_076639336.1\|590931_591603_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_002990431.1\|591599_592283_+	hypothetical protein	NA	NA	NA	NA
WP_002990429.1\|592305_593229_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	6.7e-33	38.1
WP_014407462.1\|593237_594365_+	ABC transporter permease	NA	NA	NA	NA
WP_076639335.1\|594361_595480_+	ABC transporter permease	NA	NA	NA	NA
WP_076639334.1\|596050_598783_+	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_002985256.1\|599060_599561_+	QueT transporter family protein	E7DN70	Pneumococcus_phage	5.4e-05	31.8
WP_014635380.1\|599754_601713_+	NAD-dependent DNA ligase LigA	A0A0K2QQN8	Ralstonia_phage	1.3e-102	34.9
WP_002985252.1\|601726_602749_+	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	3.6e-19	27.9
WP_002985249.1\|603140_603338_+	F0F1 ATP synthase subunit C	NA	NA	NA	NA
WP_002985244.1\|603372_604089_+	F0F1 ATP synthase subunit A	NA	NA	NA	NA
WP_002990420.1\|604106_604601_+	F0F1 ATP synthase subunit B	NA	NA	NA	NA
WP_030126744.1\|604600_605137_+	F0F1 ATP synthase subunit delta	NA	NA	NA	NA
WP_011889023.1\|605152_606658_+	F0F1 ATP synthase subunit alpha	NA	NA	NA	NA
WP_002985236.1\|606676_607552_+	F0F1 ATP synthase subunit gamma	NA	NA	NA	NA
WP_076639333.1\|607714_609124_+	F0F1 ATP synthase subunit beta	NA	NA	NA	NA
WP_002985233.1\|609133_609550_+	F0F1 ATP synthase subunit epsilon	NA	NA	NA	NA
WP_002994426.1\|609815_610073_+	DUF1146 domain-containing protein	NA	NA	NA	NA
WP_002994428.1\|610137_611409_+	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_023078815.1\|611412_611601_+	DNA-directed RNA polymerase subunit beta	NA	NA	NA	NA
WP_003057440.1\|612458_613502_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2K9L3A8	Tupanvirus	4.6e-30	34.3
WP_076639331.1\|613711_616117_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA

DBSCAN-SWA_4

651527 : 662130

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044559748.1\|651527_653738_-	LTA synthase family protein	W6LM83	Streptococcus_phage	6.5e-268	68.9
WP_002985142.1\|653845_655009_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	3.4e-143	65.1
WP_002985140.1\|655005_655692_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.0e-88	68.9
WP_076639328.1\|655785_656952_+	chorismate synthase	A0A291AU41	Pandoravirus	1.9e-32	32.2
WP_002990260.1\|657012_657354_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	2.6e-19	41.1
WP_044559750.1\|657574_658927_+	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	4.5e-30	23.8
WP_021775342.1\|659014_660283_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_021775338.1\|660312_660753_-	hypothetical protein	NA	NA	NA	NA
WP_011184383.1\|660987_662130_+	cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	1.4e-24	27.3

DBSCAN-SWA_5

753954 : 805447

Streptococcus_pyogenes_phage(47.37%)

capsid,portal,tail,terminase,integrase,holin,tRNA

attL 754534:754549|attR 809699:809714

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002990117.1\|753954_754854_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
754534:754549	attL	NA	NA	NA	NA
WP_030127486.1\|754926_756165_+	GTPase HflX	NA	NA	NA	NA
WP_002990114.1\|756157_756793_+	cystathionine beta-lyase	NA	NA	NA	NA
WP_023611152.1\|756807_757737_+	ribonuclease Z	NA	NA	NA	NA
WP_002984893.1\|757736_758501_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_076639688.1\|758497_760708_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	3.9e-71	30.2
WP_002990109.1\|760857_761376_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	3.9e-30	42.4
WP_002984890.1\|761456_762140_+	DnaD domain-containing protein	Q938N2	Temperate_phage	2.9e-09	36.8
WP_002990106.1\|762136_762793_+	endonuclease III	NA	NA	NA	NA
WP_020905114.1\|762864_763551_+\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_002984887.1\|763540_764329_+	Nif3-like dinuclear metal center hexameric protein	NA	NA	NA	NA
WP_076639687.1\|764368_765475_+	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_002992970.1\|765532_766402_+	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	2.4e-101	64.6
WP_002990099.1\|766401_766995_+	dTDP-4-dehydrorhamnose 3,5-epimerase	H9NC63	Sphingomonas_phage	3.7e-08	28.2
WP_076639686.1\|767238_768279_+	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	8.5e-69	43.9
WP_011528538.1\|768361_769501_-\|integrase	site-specific integrase	A1EAB7	Streptococcus_phage	4.4e-119	55.8
WP_011528539.1\|769622_770309_-	hypothetical protein	A0A1P8VVT3	Streptococcus_phage	5.7e-122	100.0
WP_011054825.1\|770479_770632_-	hypothetical protein	A0A1P8VVQ0	Streptococcus_phage	5.2e-20	100.0
WP_011054824.1\|770642_771020_-	ImmA/IrrE family metallo-endopeptidase	A0A1P8VVK5	Streptococcus_phage	4.0e-69	100.0
WP_011528540.1\|771003_771363_-	helix-turn-helix transcriptional regulator	A0A1P8VVN3	Streptococcus_phage	1.8e-58	98.3
WP_009881062.1\|771551_771770_+	helix-turn-helix transcriptional regulator	A0A1P8VVR5	Streptococcus_phage	4.1e-34	100.0
WP_011528542.1\|771864_772116_+	hypothetical protein	A0A1P8VVV6	Streptococcus_phage	2.8e-42	100.0
WP_011528544.1\|772296_772611_+	helix-turn-helix transcriptional regulator	A0A1P8VVN6	Streptococcus_phage	1.7e-52	100.0
WP_011528545.1\|772837_773320_+	siphovirus Gp157 family protein	A0A1P8VVS5	Streptococcus_phage	1.2e-78	100.0
WP_002995975.1\|773320_774001_+	AAA family ATPase	A0A1P8VVS4	Streptococcus_phage	1.6e-129	100.0
WP_011528546.1\|774102_775332_+	DEAD/DEAH box helicase	A0A1P8VVM2	Streptococcus_phage	3.3e-237	100.0
WP_002995969.1\|775347_775806_+	DUF669 domain-containing protein	A0A1P8VVN0	Streptococcus_phage	3.8e-82	100.0
WP_030126642.1\|775808_776621_+	bifunctional DNA primase/polymerase	A0A1P8VVM6	Streptococcus_phage	5.5e-156	99.6
WP_020905118.1\|776610_778092_+	DNA primase	A0A1P8VVM0	Streptococcus_phage	1.3e-296	100.0
WP_002995960.1\|778336_778657_+	VRR-NUC domain-containing protein	A0A1P8VVL5	Streptococcus_phage	2.0e-53	100.0
WP_011018138.1\|778640_778997_+	hypothetical protein	A0A1P8VVP9	Streptococcus_phage	5.0e-61	100.0
WP_011017568.1\|779238_779523_+	DUF3310 domain-containing protein	A0A1P8VVP5	Streptococcus_phage	7.0e-50	100.0
WP_002987593.1\|779519_779789_+	hypothetical protein	A0A1P8VVR6	Streptococcus_phage	3.1e-47	100.0
WP_011054753.1\|779798_780203_+	hypothetical protein	Q938M1	Temperate_phage	6.0e-71	100.0
WP_011054752.1\|780199_780370_+	hypothetical protein	Q938M0	Temperate_phage	4.2e-26	100.0
WP_011054751.1\|780366_780873_+	DUF1642 domain-containing protein	Q938L9	Temperate_phage	9.8e-95	100.0
WP_164997036.1\|780869_781040_+	hypothetical protein	A0A097PAS8	Streptococcus_pyogenes_phage	1.1e-26	98.2
WP_011017866.1\|781313_781754_+	ArpU family transcriptional regulator	Q938L8	Temperate_phage	5.0e-79	100.0
WP_011285571.1\|781901_782282_+	hypothetical protein	A0A097PAR5	Streptococcus_pyogenes_phage	1.0e-64	100.0
WP_021299302.1\|782271_783546_+\|terminase	PBSX family phage terminase large subunit	A0A097PAV9	Streptococcus_pyogenes_phage	1.9e-251	99.8
WP_011528552.1\|783545_784871_+\|portal	phage portal protein	A0A097PAT2	Streptococcus_pyogenes_phage	6.3e-234	95.6
WP_011528553.1\|784839_785748_+\|capsid	minor capsid protein	A0A097PBF2	Streptococcus_pyogenes_phage	2.4e-83	94.5
WP_011528554.1\|785754_785985_+	hypothetical protein	Q938K9	Temperate_phage	4.0e-19	62.5
WP_021299309.1\|786096_786666_+	DUF4355 domain-containing protein	A0A097PAW3	Streptococcus_pyogenes_phage	1.4e-60	90.5
WP_009880261.1\|786684_787575_+	hypothetical protein	A0A097PAW2	Streptococcus_pyogenes_phage	8.6e-86	99.4
WP_011528557.1\|787586_787880_+	Rho termination factor N-terminal domain-containing protein	A0A097PBF3	Streptococcus_pyogenes_phage	1.3e-46	99.0
WP_011528558.1\|787893_788238_+	hypothetical protein	A0A097PAS2	Streptococcus_pyogenes_phage	1.5e-54	99.1
WP_011528559.1\|788234_788546_+	hypothetical protein	A0A097PAW7	Streptococcus_pyogenes_phage	4.6e-47	94.2
WP_011528560.1\|788542_788938_+	hypothetical protein	A0A097PAT9	Streptococcus_pyogenes_phage	1.8e-56	93.0
WP_011528561.1\|788939_789350_+	DUF5072 family protein	A0A097PAW5	Streptococcus_pyogenes_phage	1.8e-70	99.3
WP_079890482.1\|789361_789868_+\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	8.3e-78	98.7
WP_011528563.1\|789880_790198_+	hypothetical protein	A0A097PAS6	Streptococcus_pyogenes_phage	1.9e-51	98.1
WP_011528564.1\|790170_790629_+	hypothetical protein	A0A097PAX1	Streptococcus_pyogenes_phage	7.0e-76	93.4
WP_011528565.1\|790621_792427_+\|tail	tail protein	A0A097PAU2	Streptococcus_pyogenes_phage	9.1e-252	95.5
WP_011528566.1\|792427_793912_+\|tail	phage tail family protein	A0A097PAW9	Streptococcus_pyogenes_phage	1.8e-290	98.8
WP_050336170.1\|793912_797362_+\|tail	phage tail protein	A0A097PBF5	Streptococcus_pyogenes_phage	0.0e+00	99.0
WP_011528568.1\|797366_799229_+	hypothetical protein	A0A097PAT0	Streptococcus_pyogenes_phage	0.0e+00	99.8
WP_009880247.1\|799239_799587_+	DUF1366 domain-containing protein	A0A097PAX5	Streptococcus_pyogenes_phage	3.5e-59	100.0
WP_015055952.1\|799736_800060_+	hypothetical protein	A0A097PAX2	Streptococcus_pyogenes_phage	7.7e-53	100.0
WP_011054798.1\|800059_800392_+\|holin	phage holin	A0A097PBF6	Streptococcus_pyogenes_phage	5.7e-51	100.0
WP_011054797.1\|800393_801158_+	CHAP domain-containing protein	A0A097PAT3	Streptococcus_pyogenes_phage	1.5e-150	100.0
WP_011054796.1\|801169_801772_+	hypothetical protein	A0A097PAX9	Streptococcus_pyogenes_phage	7.8e-91	98.8
WP_011528569.1\|801782_802556_+	hypothetical protein	A0A097PAV0	Streptococcus_pyogenes_phage	4.6e-128	94.6
WP_009880241.1\|802565_802787_+	hypothetical protein	A0A097PAX7	Streptococcus_pyogenes_phage	2.5e-18	84.5
WP_011528570.1\|802786_803446_+	hypothetical protein	A0A097PBF7	Streptococcus_pyogenes_phage	6.3e-118	96.3
WP_011017966.1\|803514_803949_-	hypothetical protein	NA	NA	NA	NA
WP_011285611.1\|804220_805021_-	streptodornase Sda3	NA	NA	NA	NA
WP_011528571.1\|805258_805447_+	hypothetical protein	A3F673	Streptococcus_phage	6.1e-18	73.3
809699:809714	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1141855 : 1247912

116

Streptococcus_phage(47.14%)

capsid,protease,portal,tail,terminase,head,integrase,tRNA

attL 1182937:1182956|attR 1225616:1225635

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011184658.1\|1141855_1142551_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_020905286.1\|1142569_1143331_-	DUF3169 family protein	NA	NA	NA	NA
WP_002989220.1\|1143327_1143543_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_076639299.1\|1143903_1146522_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	1.1e-61	34.1
WP_020905289.1\|1146908_1147964_-	peptidylprolyl isomerase PrsA	NA	NA	NA	NA
WP_002989211.1\|1148026_1148734_-	O-methyltransferase	A0A2P1JQT7	Mycobacterium_phage	2.6e-08	27.2
WP_002995765.1\|1148799_1149996_-	OFA family MFS transporter	NA	NA	NA	NA
WP_011054652.1\|1150371_1152177_-	oligoendopeptidase F	NA	NA	NA	NA
WP_002983995.1\|1152189_1153152_-	competence protein CoiA	NA	NA	NA	NA
WP_020905292.1\|1153447_1154164_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_009880651.1\|1154282_1154987_-	glucosamine-6-phosphate deaminase	NA	NA	NA	NA
WP_076639300.1\|1155188_1156217_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_002983986.1\|1156223_1157444_+	DUF3114 domain-containing protein	NA	NA	NA	NA
WP_020905297.1\|1158131_1158380_-	hypothetical protein	NA	NA	NA	NA
WP_020905298.1\|1158434_1158590_-	hypothetical protein	NA	NA	NA	NA
WP_020905299.1\|1158751_1159357_-	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	3.9e-58	52.7
WP_020905300.1\|1159453_1160494_-	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_076639301.1\|1160564_1162808_-	DNA internalization-related competence protein ComEC/Rec2	M1PSD2	Streptococcus_phage	7.5e-54	58.2
WP_002983967.1\|1162788_1163451_-	ComEA family DNA-binding protein	NA	NA	NA	NA
WP_011054661.1\|1163650_1164391_-	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_020905303.1\|1164430_1165285_+\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
WP_011017953.1\|1165274_1165553_+	GIY-YIG nuclease family protein	W8W2G4	Invertebrate_iridovirus	7.9e-06	36.0
WP_020905304.1\|1165576_1167577_-	potassium transporter Kup	M1IBC2	Acanthocystis_turfacea_Chlorella_virus	3.4e-66	34.0
WP_020905305.1\|1167704_1169324_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.5e-59	36.5
WP_020905306.1\|1169630_1171175_-	peptide chain release factor 3	A0A1B0RXH7	Streptococcus_phage	1.1e-35	28.8
WP_011017956.1\|1171422_1172118_-	TIGR02206 family membrane protein	NA	NA	NA	NA
WP_076639302.1\|1172197_1173589_-	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase	NA	NA	NA	NA
WP_020905307.1\|1173787_1174834_-	D-alanine--D-alanine ligase	NA	NA	NA	NA
WP_002983939.1\|1174934_1175531_-	recombination protein RecR	NA	NA	NA	NA
WP_076639303.1\|1176329_1177109_-	formate/nitrite transporter family protein	NA	NA	NA	NA
WP_002989140.1\|1177232_1177775_-	hypothetical protein	NA	NA	NA	NA
WP_002983930.1\|1177935_1178457_-	transcription repressor NadR	NA	NA	NA	NA
WP_002983928.1\|1178563_1179259_-	phosphoglycerate mutase	NA	NA	NA	NA
WP_023610138.1\|1179497_1180433_+	dihydroorotate oxidase	A0A1V0SH91	Hokovirus	3.0e-65	44.8
WP_076639304.1\|1180732_1182595_-	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	1.9e-90	34.0
1182937:1182956	attL	NA	NA	NA	NA
WP_032463717.1\|1183125_1183308_-	hypothetical protein	A3F673	Streptococcus_phage	4.4e-21	81.7
WP_021340779.1\|1183422_1184211_-	streptococcal pyrogenic exotoxin SpeL	Q938J1	Temperate_phage	9.1e-47	41.4
WP_032463716.1\|1184492_1185206_-	streptococcal pyrogenic exotoxin SpeM	Q938J1	Temperate_phage	9.0e-78	59.1
WP_003051628.1\|1185589_1186183_-	GNAT family N-acetyltransferase	A0A0A8WFI2	Clostridium_phage	2.4e-23	38.2
WP_011018107.1\|1186182_1186386_-	hypothetical protein	NA	NA	NA	NA
WP_002994484.1\|1187249_1187942_-	AP2 domain-containing protein	A0A2H4J2S8	uncultured_Caudovirales_phage	1.5e-32	34.2
WP_023078271.1\|1188174_1188732_-	glycoside hydrolase family 73 protein	Q938J4	Temperate_phage	2.8e-95	89.2
WP_011054731.1\|1188842_1189028_-	hypothetical protein	Q938J5	Temperate_phage	1.7e-25	100.0
WP_023078532.1\|1189024_1189321_-	hypothetical protein	Q938J6	Temperate_phage	2.9e-46	99.0
WP_023611372.1\|1189331_1189964_-	hypothetical protein	Q938J7	Temperate_phage	2.6e-44	50.0
WP_032463718.1\|1189966_1190395_-	DUF1617 family protein	Q938J8	Temperate_phage	9.8e-64	89.3
WP_076639305.1\|1190406_1192293_-	gp58-like family protein	Q938J9	Temperate_phage	8.1e-219	84.9
WP_032463712.1\|1192307_1193321_-	hyaluronoglucosaminidase	Q938K0	Temperate_phage	1.6e-181	98.2
WP_050436577.1\|1193320_1195426_-\|tail	phage tail protein	A3F656	Streptococcus_phage	2.3e-129	43.1
WP_030127447.1\|1195422_1196193_-\|tail	phage tail family protein	A1EAB1	Streptococcus_phage	1.2e-56	45.0
WP_050436576.1\|1196192_1198940_-\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	8.3e-55	36.4
WP_030127445.1\|1198939_1199257_-	hypothetical protein	A1EAF6	Streptococcus_phage	6.9e-14	44.4
WP_030127444.1\|1199277_1199646_-	hypothetical protein	NA	NA	NA	NA
WP_030127443.1\|1199699_1200218_-\|tail	phage major tail protein, TP901-1 family	A1EAF4	Streptococcus_phage	2.2e-41	51.7
WP_030127442.1\|1200205_1200604_-	DUF3168 domain-containing protein	A1EAF3	Streptococcus_phage	3.8e-25	44.5
WP_030127441.1\|1200600_1200957_-	HK97 gp10 family phage protein	A1EAF2	Streptococcus_phage	4.7e-19	44.0
WP_032463711.1\|1200956_1201253_-	hypothetical protein	A0A1P8BKV3	Lactococcus_phage	9.6e-10	35.6
WP_030127439.1\|1201249_1201603_-\|head,tail	phage head-tail connector protein	A0A2H4J002	uncultured_Caudovirales_phage	3.9e-26	52.1
WP_030127438.1\|1201614_1201881_-	hypothetical protein	NA	NA	NA	NA
WP_030127437.1\|1201892_1202942_-\|capsid	major capsid protein	A0A286QR01	Streptococcus_phage	1.8e-106	57.7
WP_002990036.1\|1202944_1203325_-	structural protein	A0A0K2CNR0	Brevibacillus_phage	6.4e-06	36.3
WP_030127436.1\|1203334_1203868_-	DUF4355 domain-containing protein	A0A141E0S7	Streptococcus_phage	1.8e-14	82.5
WP_030127435.1\|1204011_1204278_-	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	4.1e-28	77.3
WP_032463710.1\|1204293_1205208_-\|capsid	minor capsid protein	A1EAE3	Streptococcus_phage	2.2e-73	50.0
WP_032461297.1\|1205188_1206679_-\|portal	phage portal protein	C9W9H5	Streptococcus_virus	1.3e-142	54.0
WP_014635515.1\|1206690_1207998_-\|terminase	PBSX family phage terminase large subunit	A0A2H4IYR5	uncultured_Caudovirales_phage	2.9e-183	75.0
WP_030127432.1\|1207975_1208428_-\|terminase	terminase small subunit	A7J290	Streptococcus_phage	1.7e-66	95.7
WP_011054881.1\|1208517_1208934_-	transcriptional regulator	A7J289	Streptococcus_phage	3.3e-72	99.3
WP_023079210.1\|1208917_1209064_-	hypothetical protein	NA	NA	NA	NA
WP_011054882.1\|1209066_1209339_-	hypothetical protein	A7J287	Streptococcus_phage	5.7e-25	73.3
WP_164972002.1\|1209331_1209502_-	hypothetical protein	A7J285	Streptococcus_phage	9.0e-21	92.3
WP_030127431.1\|1209502_1210825_-	DEAD/DEAH box helicase family protein	A7J284	Streptococcus_phage	4.3e-251	97.5
WP_011054885.1\|1210821_1211097_-	VRR-NUC domain-containing protein	A7J283	Streptococcus_phage	2.9e-45	96.7
WP_032463709.1\|1211482_1213867_-	DNA primase	A7J282	Streptococcus_phage	6.3e-277	94.6
WP_030127429.1\|1213871_1215794_-	DNA polymerase	A7J280	Streptococcus_phage	0.0e+00	99.1
WP_086934854.1\|1215836_1216400_-	DUF2815 family protein	D2J040	Enterococcus_phage	3.3e-51	58.5
WP_011888943.1\|1216408_1217566_-	DUF2800 domain-containing protein	A7J278	Streptococcus_phage	1.0e-216	98.2
WP_030127427.1\|1217565_1217865_-	hypothetical protein	A7J277	Streptococcus_phage	3.7e-41	96.0
WP_030127426.1\|1217952_1218156_-	hypothetical protein	A7J276	Streptococcus_phage	3.7e-29	89.6
WP_017647437.1\|1218152_1218305_-	hypothetical protein	A7J275	Streptococcus_phage	9.9e-19	98.0
WP_030127425.1\|1218301_1218688_-	hypothetical protein	A7J274	Streptococcus_phage	6.8e-56	87.4
WP_030127424.1\|1218684_1218888_-	hypothetical protein	NA	NA	NA	NA
WP_023611037.1\|1218880_1219051_-	hypothetical protein	A7J273	Streptococcus_phage	2.9e-19	87.5
WP_014411880.1\|1219052_1219364_-	hypothetical protein	A0A1S5SA25	Streptococcus_phage	1.4e-43	78.6
WP_011054585.1\|1219441_1219627_-	helix-turn-helix transcriptional regulator	A0A1X9I6I3	Streptococcus_phage	3.3e-16	72.1
WP_011284879.1\|1219793_1220033_+	hypothetical protein	NA	NA	NA	NA
WP_002984292.1\|1220182_1220392_+	hypothetical protein	NA	NA	NA	NA
WP_001157159.1\|1220637_1220844_-	helix-turn-helix domain-containing protein	A0A1X9I5S3	Streptococcus_phage	1.1e-17	64.7
WP_050429000.1\|1220893_1221400_+	hypothetical protein	NA	NA	NA	NA
WP_021340823.1\|1221396_1221543_-	hypothetical protein	NA	NA	NA	NA
WP_030127422.1\|1221597_1222197_+	hypothetical protein	A0A097PAT4	Streptococcus_pyogenes_phage	9.1e-108	99.5
WP_076636802.1\|1222227_1222386_-	hypothetical protein	A0A097PAP2	Streptococcus_pyogenes_phage	1.1e-23	98.1
WP_030127421.1\|1222775_1223534_+	helix-turn-helix domain-containing protein	A0A097PBE5	Streptococcus_pyogenes_phage	3.1e-84	65.9
WP_030127420.1\|1223568_1224249_+	hypothetical protein	A0A097PAS7	Streptococcus_pyogenes_phage	1.2e-74	87.7
WP_003051793.1\|1224385_1225528_+\|integrase	site-specific integrase	M1NRJ9	Streptococcus_phage	2.4e-173	77.4
WP_002983920.1\|1225617_1225893_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	2.6e-25	73.0
1225616:1225635	attR	NA	NA	NA	NA
WP_002989129.1\|1225991_1226579_-	YpmS family protein	NA	NA	NA	NA
WP_002992620.1\|1226556_1227399_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_161237429.1\|1227391_1228243_-	DegV family protein	A0A0N9SI50	Staphylococcus_phage	9.2e-13	35.7
WP_076639306.1\|1228458_1229373_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_076639307.1\|1229544_1231206_-	DNA repair protein RecN	NA	NA	NA	NA
WP_002983907.1\|1231226_1231697_-	arginine repressor	NA	NA	NA	NA
WP_011017996.1\|1231683_1232511_-	TlyA family RNA methyltransferase	NA	NA	NA	NA
WP_076639308.1\|1232503_1233376_-	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_002983901.1\|1233375_1233591_-	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_076639309.1\|1233568_1234909_-	exodeoxyribonuclease VII large subunit	A0A1V0SIT1	Klosneuvirus	6.3e-40	30.9
WP_010922486.1\|1235061_1235916_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	2.0e-39	39.8
WP_076639310.1\|1236123_1237818_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	4.5e-128	42.2
WP_023610117.1\|1237995_1239405_-	deoxyribodipyrimidine photo-lyase	A0A1V0SGL1	Hokovirus	8.8e-61	32.8
WP_010922488.1\|1239553_1240288_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.2e-34	38.4
WP_011054708.1\|1240287_1240974_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_002983885.1\|1241100_1241331_-	YkuJ family protein	NA	NA	NA	NA
WP_002983882.1\|1241628_1243911_+\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A2C9CYX3	Yersinia_phage	1.1e-124	39.6
WP_020905319.1\|1244038_1244494_+	NUDIX hydrolase	NA	NA	NA	NA
WP_002983878.1\|1244544_1244847_+	DUF1827 family protein	NA	NA	NA	NA
WP_076639311.1\|1245110_1247912_-\|tRNA	isoleucine--tRNA ligase	H2EEZ0	Moumouvirus	1.4e-70	27.0

DBSCAN-SWA_7

1281217 : 1325369

Temperate_phage(79.03%)

capsid,portal,tail,terminase,holin,integrase

attL 1306823:1306839|attR 1325548:1325564

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076639316.1\|1281217_1282951_-	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	2.3e-26	33.2
WP_023610925.1\|1282947_1283688_-	response regulator	NA	NA	NA	NA
WP_011054726.1\|1283932_1284115_-	hypothetical protein	A3F673	Streptococcus_phage	2.6e-18	76.7
WP_011054727.1\|1284460_1285036_-	hypothetical protein	Q938J0	Temperate_phage	1.7e-111	100.0
WP_011054728.1\|1285511_1286291_-	streptococcal pyrogenic exotoxin SpeK	Q938J1	Temperate_phage	5.4e-145	100.0
WP_076639317.1\|1286594_1287461_-	DUF334 domain-containing protein	Q938J2	Temperate_phage	2.4e-133	99.3
WP_011017840.1\|1287448_1287973_-	DUF4065 domain-containing protein	Q938J3	Temperate_phage	4.0e-99	100.0
WP_011054730.1\|1288112_1289315_-	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	3.3e-242	100.0
WP_011054444.1\|1289430_1289658_-\|holin	phage holin	A7J2B3	Streptococcus_phage	7.6e-31	98.7
WP_011017397.1\|1289654_1289927_-	hypothetical protein	A7J2B2	Streptococcus_phage	5.5e-36	91.0
WP_011054443.1\|1289938_1290571_-	hypothetical protein	Q938J7	Temperate_phage	2.0e-44	49.5
WP_002988448.1\|1290573_1291002_-	DUF1617 family protein	Q938J8	Temperate_phage	8.1e-58	84.3
WP_047235372.1\|1291013_1292903_-	gp58-like family protein	Q938J9	Temperate_phage	1.4e-189	75.6
WP_011284842.1\|1292913_1293243_-	hypothetical protein	NA	NA	NA	NA
WP_011284843.1\|1293229_1294444_-	hypothetical protein	A3F657	Streptococcus_phage	5.0e-44	49.5
WP_076639318.1\|1294440_1296588_-\|tail	phage tail protein	Q938K1	Temperate_phage	0.0e+00	93.8
WP_076639319.1\|1296584_1297301_-\|tail	phage tail family protein	Q938K2	Temperate_phage	1.8e-131	95.8
WP_076639320.1\|1297297_1300558_-	tape measure protein	Q938K3	Temperate_phage	0.0e+00	99.8
WP_011054739.1\|1300547_1301129_-	hypothetical protein	Q938K4	Temperate_phage	1.3e-106	100.0
WP_011054740.1\|1301132_1301567_-	hypothetical protein	Q938K5	Temperate_phage	2.6e-72	100.0
WP_011054741.1\|1301605_1302091_-	hypothetical protein	Q938K6	Temperate_phage	1.6e-86	100.0
WP_010922084.1\|1302090_1302489_-\|capsid	phage capsid protein	Q79S87	Temperate_phage	3.5e-71	100.0
WP_010922083.1\|1302485_1302842_-	hypothetical protein	Q79S88	Temperate_phage	4.5e-62	100.0
WP_010922082.1\|1302841_1303174_-	hypothetical protein	Q79S86	Temperate_phage	9.6e-59	100.0
WP_011054743.1\|1303163_1303580_-	hypothetical protein	Q938K7	Temperate_phage	1.1e-56	100.0
WP_010922080.1\|1303633_1304452_-\|capsid	N4-gp56 family major capsid protein	Q79S85	Temperate_phage	4.0e-146	100.0
WP_011106689.1\|1304455_1305070_-	hypothetical protein	Q938K8	Temperate_phage	1.3e-96	100.0
WP_011054745.1\|1305195_1305462_-	hypothetical protein	Q938K9	Temperate_phage	1.5e-38	100.0
WP_002986829.1\|1305523_1305763_-	hypothetical protein	Q938L0	Temperate_phage	2.8e-36	100.0
WP_011054746.1\|1305734_1307213_-\|capsid	phage minor capsid protein	Q938L1	Temperate_phage	8.2e-275	100.0
1306823:1306839	attL	NA	NA	NA	NA
WP_002986832.1\|1307217_1308720_-\|portal	phage portal protein	Q938L2	Temperate_phage	5.4e-282	100.0
WP_010922074.1\|1308733_1309945_-\|terminase	PBSX family phage terminase large subunit	Q938L3	Temperate_phage	3.7e-225	99.7
WP_011054747.1\|1310027_1310501_-	hypothetical protein	Q938L4	Temperate_phage	4.3e-76	99.4
WP_002986841.1\|1310551_1310929_-	ASCH domain-containing protein	Q938L5	Temperate_phage	1.7e-67	100.0
WP_076639321.1\|1310989_1311373_-	GNAT family N-acetyltransferase	B5SP24	Lactococcus_phage	3.9e-35	58.5
WP_076639322.1\|1311398_1311917_-	ParB N-terminal domain-containing protein	Q938L7	Temperate_phage	1.1e-88	99.4
WP_011054748.1\|1311997_1312255_+	hypothetical protein	NA	NA	NA	NA
WP_011017866.1\|1312893_1313334_-	ArpU family transcriptional regulator	Q938L8	Temperate_phage	5.0e-79	100.0
WP_164997036.1\|1313607_1313778_-	hypothetical protein	A0A097PAS8	Streptococcus_pyogenes_phage	1.1e-26	98.2
WP_011054751.1\|1313774_1314281_-	DUF1642 domain-containing protein	Q938L9	Temperate_phage	9.8e-95	100.0
WP_011054752.1\|1314277_1314448_-	hypothetical protein	Q938M0	Temperate_phage	4.2e-26	100.0
WP_011054753.1\|1314444_1314849_-	hypothetical protein	Q938M1	Temperate_phage	6.0e-71	100.0
WP_011054754.1\|1314858_1315128_-	hypothetical protein	Q938M2	Temperate_phage	4.0e-47	100.0
WP_011054755.1\|1315124_1315409_-	DUF3310 domain-containing protein	Q938M3	Temperate_phage	5.4e-50	100.0
WP_011054756.1\|1315402_1315654_-	hypothetical protein	Q938M4	Temperate_phage	6.8e-41	100.0
WP_011054757.1\|1315650_1316007_-	hypothetical protein	A0A1P8VVP9	Streptococcus_phage	1.6e-51	85.6
WP_011054758.1\|1316003_1316444_-	RusA family crossover junction endodeoxyribonuclease	A0A097PAS0	Streptococcus_pyogenes_phage	8.5e-79	97.3
WP_011106686.1\|1316443_1316647_-	hypothetical protein	Q938M6	Temperate_phage	4.7e-32	100.0
WP_011054759.1\|1316652_1317072_-	single-stranded DNA-binding protein	Q938M7	Temperate_phage	1.6e-71	100.0
WP_011054760.1\|1317064_1317739_-	ERF family protein	Q938M8	Temperate_phage	2.5e-106	100.0
WP_011018142.1\|1317739_1318222_-	siphovirus Gp157 family protein	Q938M9	Temperate_phage	8.2e-51	100.0
WP_011054761.1\|1318243_1318498_-	hypothetical protein	Q938N0	Temperate_phage	7.4e-43	100.0
WP_011284979.1\|1318508_1318649_-	hypothetical protein	A0A1X9I6Y1	Streptococcus_phage	7.5e-05	52.3
WP_011054762.1\|1318645_1318879_-	hypothetical protein	Q938N1	Temperate_phage	5.0e-38	100.0
WP_011054763.1\|1318859_1319273_-	DnaD domain protein	Q938N2	Temperate_phage	2.1e-63	100.0
WP_011106684.1\|1319394_1319652_-	hypothetical protein	A0A1S5SFN6	Streptococcus_phage	1.2e-11	46.4
WP_011054765.1\|1319745_1319931_-	hypothetical protein	Q938N3	Temperate_phage	1.1e-24	100.0
WP_002988339.1\|1319959_1320217_-	hypothetical protein	NA	NA	NA	NA
WP_011054766.1\|1320462_1320717_-	hypothetical protein	NA	NA	NA	NA
WP_002986887.1\|1320705_1320906_+	KTSC domain-containing protein	A0A1S5S8T9	Streptococcus_phage	6.3e-21	72.3
WP_002986888.1\|1320902_1321052_-	hypothetical protein	Q938N4	Temperate_phage	1.8e-20	100.0
WP_011054767.1\|1321084_1321813_-	phage antirepressor KilAC domain-containing protein	Q938N5	Temperate_phage	6.9e-134	100.0
WP_002986891.1\|1321823_1322015_-	hypothetical protein	A7J270	Streptococcus_phage	1.2e-24	90.5
WP_011054768.1\|1322810_1323170_+	helix-turn-helix transcriptional regulator	Q938N6	Temperate_phage	1.1e-60	100.0
WP_002986894.1\|1323183_1323564_+	hypothetical protein	Q938N7	Temperate_phage	5.3e-69	100.0
WP_002986895.1\|1323574_1324096_+	hypothetical protein	Q938N8	Temperate_phage	2.3e-67	100.0
WP_002986896.1\|1324214_1325369_+\|integrase	site-specific integrase	Q938N9	Temperate_phage	2.8e-206	100.0
1325548:1325564	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NZ_LS483437.1|WP_003051628.1|1185589_1186183_-|GNAT-family-N-acetyltransferase

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_LS483437.1|WP_003051628.1|1185589_1186183_-|GNAT-family-N-acetyltransferase

1185589_1186183_-

197 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|89	0.46875	0.9695431472081218	0.9792746113989638

1141855-1247912

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LS483437

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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