CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483485	Aggregatibacter aphrophilus strain NCTC11096 chromosome 1	2 crisprs	cas3,DEDDh,DinG,WYL,cas2,cas1,cas4,cas7,cas8c,cas5	1	5	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483485_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483485_1

1769904-1770045

Orphan

Consensus_repeat	Method
ACCTTGCCAAGGTCGGGGTCGCGAGTTCGAGCCTCGTTTCCCGCTCCA	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of NZ_LS483485_1

>merge|NZ_LS483485|1|1769904-1770045|CRISPRCasFinder
ACCTTGCCAAGGTCGGGGTCGCGAGTTCGAGCCTCGTTTCCCGCTCCATTCTCAACATCAAGTTATGCGGGAATAGCTCAGTTGGTAGAGCACAACCTTGCCAAGGTTGGGGTCGCGAGTTCGAGCCTCGTTTCCCGCTCCA

>NZ_LS483485|1|1|1769904-1770045|CRISPRCasFinder
ACCTTGCCAAGGTCGGGGTCGCGAGTTCGAGCCTCGTTTCCCGCTCCA	TTCTCAACATCAAGTTATGCGGGAATAGCTCAGTTGGTAGAGCACA
ACCTTGCCAAGGTTGGGGTCGCGAGTTCGAGCCTCGTTTCCCGCTCCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483485.1\|WP_083015757.1\|1765746_1767474_-\|phosphoenolpyruvate-protein-phosphotransferase-PtsI	unknown	unknown	gnl\|CDD\|183017
NZ_LS483485.1\|WP_005702982.1\|1777029_1777332_+\|RNA-chaperone-Hfq	unknown	unknown	gnl\|CDD\|179001
NZ_LS483485.1\|WP_005700304.1\|1767613_1767871_-\|phosphocarrier-protein-Hpr	unknown	unknown	gnl\|CDD\|182777
NZ_LS483485.1\|WP_111300450.1\|1775949_1776903_+\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	unknown	unknown	gnl\|CDD\|234626
NZ_LS483485.1\|WP_005700306.1\|1765185_1765686_-\|PTS-glucose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|181859
NZ_LS483485.1\|WP_083015768.1\|1774096_1775944_+\|DNA-mismatch-repair-endonuclease-MutL	unknown	unknown	gnl\|CDD\|234630
NZ_LS483485.1\|WP_111299776.1\|1780886_1782293_-\|YcjX-family-protein	unknown	unknown	gnl\|CDD\|225648
NZ_LS483485.1\|WP_111299789.1\|1763007_1765047_+\|oligopeptidase-A	unknown	unknown	gnl\|CDD\|182832
NZ_LS483485.1\|WP_111299788.1\|1768098_1769139_-\|small-ribosomal-subunit-biogenesis-GTPase-RsgA	unknown	unknown	gnl\|CDD\|237039
NZ_LS483485.1\|WP_050326287.1\|1760902_1762471_-\|peptide-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173869
NZ_LS483485.1\|WP_172452426.1\|1777415_1778729_+\|GTPase-HflX	unknown	unknown	gnl\|CDD\|182934
NZ_LS483485.1\|WP_111299786.1\|1770258_1771884_+\|sulfatase-like-hydrolase/transferase	unknown	unknown	gnl\|CDD\|293741
NZ_LS483485.1\|WP_111299780.1\|1778725_1779685_-\|sigma-54-interacting-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225821
NZ_LS483485.1\|WP_005700313.1\|1758296_1758950_+\|GTP-cyclohydrolase-II	unknown	unknown	gnl\|CDD\|234745
NZ_LS483485.1\|WP_005700308.1\|1762509_1762875_-\|YbaN-family-protein	unknown	unknown	gnl\|CDD\|377291
NZ_LS483485.1\|WP_111299784.1\|1772116_1772593_+\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE	unknown	unknown	gnl\|CDD\|182615
NZ_LS483485.1\|WP_111299778.1\|1779781_1780876_-\|TIGR01620-family-protein	unknown	unknown	gnl\|CDD\|235449
NZ_LS483485.1\|WP_005700312.1\|1760066_1760864_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483485.1\|WP_111299782.1\|1772606_1774097_+\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|236692
NZ_LS483485.1\|WP_005702992.1\|1769210_1769756_+\|oligoribonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|235429

Protein	Function_ID	Function_description	E-value
NZ_LS483485.1\|WP_083015757.1\|1765746_1767474_-\|phosphoenolpyruvate-protein-phosphotransferase-PtsI	gnl\|CDD\|183017	PRK11177, PRK11177, phosphoenolpyruvate-protein phosphotransferase PtsI.	0
NZ_LS483485.1\|WP_005702982.1\|1777029_1777332_+\|RNA-chaperone-Hfq	gnl\|CDD\|179001	PRK00395, hfq, RNA-binding protein Hfq; Provisional.	3.41317e-43
NZ_LS483485.1\|WP_005700304.1\|1767613_1767871_-\|phosphocarrier-protein-Hpr	gnl\|CDD\|182777	PRK10850, PRK10850, phosphocarrier protein Hpr.	6.74062e-37
NZ_LS483485.1\|WP_111300450.1\|1775949_1776903_+\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	gnl\|CDD\|234626	PRK00091, miaA, tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed.	5.79413e-165
NZ_LS483485.1\|WP_005700306.1\|1765185_1765686_-\|PTS-glucose-transporter-subunit-IIA	gnl\|CDD\|181859	PRK09439, PRK09439, PTS system glucose-specific transporter subunit; Provisional.	1.97946e-103
NZ_LS483485.1\|WP_083015768.1\|1774096_1775944_+\|DNA-mismatch-repair-endonuclease-MutL	gnl\|CDD\|234630	PRK00095, mutL, DNA mismatch repair endonuclease MutL.	0
NZ_LS483485.1\|WP_111299776.1\|1780886_1782293_-\|YcjX-family-protein	gnl\|CDD\|225648	COG3106, COG3106, Predicted ATPase [General function prediction only].	0
NZ_LS483485.1\|WP_111299789.1\|1763007_1765047_+\|oligopeptidase-A	gnl\|CDD\|182832	PRK10911, PRK10911, oligopeptidase A; Provisional.	0
NZ_LS483485.1\|WP_111299788.1\|1768098_1769139_-\|small-ribosomal-subunit-biogenesis-GTPase-RsgA	gnl\|CDD\|237039	PRK12288, PRK12288, small ribosomal subunit biogenesis GTPase RsgA.	0
NZ_LS483485.1\|WP_050326287.1\|1760902_1762471_-\|peptide-ABC-transporter-substrate-binding-protein	gnl\|CDD\|173869	cd08504, PBP2_OppA, The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding component of an ATP-binding cassette (ABC)-type oligopeptide transport system comprised of 5 subunits. The transport system OppABCDEF contains two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	2.59008e-139
NZ_LS483485.1\|WP_172452426.1\|1777415_1778729_+\|GTPase-HflX	gnl\|CDD\|182934	PRK11058, PRK11058, GTPase HflX; Provisional.	0
NZ_LS483485.1\|WP_111299786.1\|1770258_1771884_+\|sulfatase-like-hydrolase/transferase	gnl\|CDD\|293741	cd16017, LptA, Lipooligosaccharide Phosphoethanolamine Transferase A (LptA) or Lipid A Phosphoethanolamine Transferase. Lipooligosaccharide Phosphoethanolamine Transferase A (LptA) or Lipid A Phosphoethanolamine Transferase catalyzes the modification of the lipid A headgroups by phosphoethanolamine (PEA) or 4-amino-arabinose residues. Lipopolysaccharides, also called endotoxins, protect bacterial pathogens from antimicrobial peptides and have roles in virulence. The PEA modified lipid A increases resistance to the cationic cyclic polypeptide antibiotic, polymyxin. Lipid A PEA transferases usually consist of a transmembrane domain anchoring the enzyme to the periplasmic face of the cytoplasmic membrane.	5.47876e-76
NZ_LS483485.1\|WP_111299780.1\|1778725_1779685_-\|sigma-54-interacting-transcriptional-regulator	gnl\|CDD\|225821	COG3283, TyrR, Transcriptional regulator of aromatic amino acids metabolism [Transcription / Amino acid transport and metabolism].	4.51275e-161
NZ_LS483485.1\|WP_005700313.1\|1758296_1758950_+\|GTP-cyclohydrolase-II	gnl\|CDD\|234745	PRK00393, ribA, GTP cyclohydrolase II RibA.	2.81711e-134
NZ_LS483485.1\|WP_005700308.1\|1762509_1762875_-\|YbaN-family-protein	gnl\|CDD\|377291	pfam04304, DUF454, Protein of unknown function (DUF454). Predicted membrane protein.	3.66935e-40
NZ_LS483485.1\|WP_111299784.1\|1772116_1772593_+\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE	gnl\|CDD\|182615	PRK10646, PRK10646, tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE.	1.94729e-60
NZ_LS483485.1\|WP_111299778.1\|1779781_1780876_-\|TIGR01620-family-protein	gnl\|CDD\|235449	PRK05415, PRK05415, hypothetical protein; Provisional.	2.56761e-154
NZ_LS483485.1\|WP_111299782.1\|1772606_1774097_+\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|236692	PRK10431, PRK10431, N-acetylmuramoyl-l-alanine amidase II; Provisional.	1.68014e-106
NZ_LS483485.1\|WP_005702992.1\|1769210_1769756_+\|oligoribonuclease	gnl\|CDD\|235429	PRK05359, PRK05359, oligoribonuclease; Provisional.	3.29982e-134

>NZ_LS483485.1|WP_005702992.1|1769210_1769756_+|oligoribonuclease
MELDKQNLIWIDLEMTGLDPEKERIIEIATIVTDKNLNILAEGPVLAVHQPDELLNKMSEWCVKTHTANGLVERVKASKLNERAAELQTLDFLKKYVPKGTSPICGNSVAQDKRFLFKYMPELADYFHYRHLDVSTLKELAARWKPEILNGFTKQNTHLALDDIRESIKELAYYREHFLNI
>NZ_LS483485.1|WP_111299788.1|1768098_1769139_-|small-ribosomal-subunit-biogenesis-GTPase-RsgA
MSKPKLTQNQKRRIQSNNNKVLHRHQKKEIEWRDDMLGESQEGLVVTRYARHADVENAQGEIFRCNLRRTLSGVVVGDHVIWRQGNEQLQGVSGVIEGIHPRKNEISRPDYYDGIKVIAANIDRIIIISSVLPSLSLNIIDRYLVVCEEANIEPIIVLNKVDMLTEAQWLEADELLAIYRKIGYQTLMLSAQSGKNLEKLTALLSHGVSIFVGQSGVGKSSLINAVLPHVDAQVGEVSATSGLGQHTTTSSCLYHLPQGGSLIDSPGIREFGLWHLEEEQITKGYREFQTVLGTCKFRDCKHLSDPGCALCQAVEEGKISTVRYENYHRLLASRNEMKSQRHFSSE
>NZ_LS483485.1|WP_005700304.1|1767613_1767871_-|phosphocarrier-protein-Hpr
MYSKDVEITAPNGLHTRPAAQFVKEAKAFASDITVSSAGKSASAKSLFKLQTLALTQGTVITISAEGEDAEKAVEHLVALIPTLE
>NZ_LS483485.1|WP_083015757.1|1765746_1767474_-|phosphoenolpyruvate-protein-phosphotransferase-PtsI
MISGIPASPGIVFGKALVLKEEKIVLDTQKIKDSQIENEIARFYAGRDAAVEQLNSIKDRAYQSLGEEKAAIFEGHLMILEDEELEEEIIDYLRSNHVNAAVAANVVIDQQVAMLSEIDDEYLKERAGDIRDIGNRLIKNILGMHIVDLGEINEEAILVAYDLTPSETAQLNLDKVLGFVTDIGGRTSHTSIMARSLELPAIVGTNNVTEKVKTGDFLILDALNNAVYVNPSQQEIQRLKTLQDKLAEEKAELAKLKDLPALTLDGHQVDVVANIGTIRDVEGAERNGAEGVGLYRTEFLFMDRDQLPSEEEQFIAYKEVVEAMNGNLVVLRTMDIGGDKELPYLNLPKEMNPFLGWRAIRIALDRREILNAQLRAVLRASAYGRLAVMFPMIISVEEIRELKSVIEELKVELRNEGKAFDEDIQVGIMVETPSAAVNAKFLAKEVDFFSIGTNDLTQYTLAVDRGNELISHLYNPMSPSVLNLIKQVIDASHAEGKWTGMCGELAGDERATILLLGMGLDEFSMSAISVPRIKKLIRNVNYQDAKLLAEKALQQPTAAEIEQLISDFLAEKALN
>NZ_LS483485.1|WP_005700306.1|1765185_1765686_-|PTS-glucose-transporter-subunit-IIA
MGLFDKLFGSKDKKAVDVEIYAPLSGEIVNIEDVPDVVFSEKIVGDGVAIRPTGNKLVAPVDGVVGKIFETNHAFSMESKEGVELFVHFGIDTVELKGEGFTRVAQEGQSVKRGDTIIELDLPLLEAKAKSVLTPVVISNMDEISNIEKKSGEVVAGDSVVLVLKK
>NZ_LS483485.1|WP_111299789.1|1763007_1765047_+|oligopeptidase-A
MSNPLLTPTDLPAFSKIEPQYIEPAIKQLIEENRATVEHLLKQPHFTWENFILPLAEAGDRLSKVWSPISHLNSVKNSPELREAYQACLPLLAEYGTWVGQHQGLYEAYLQLKNSPEFANYSQAQKKAIENSLRDFKLSGISLPAEKQKRYGEIVARLSELTSQFSNNVLDATMGWEKIIEDESQLKGLPESALQAAKQSAESKGLSGYRFTLEFPSYIPVMTYCENRELREEMYHAFATRASDQGPNAGKWDNSALMQEILSLRVDLAKLLDFNTYTELSLATKMAETPQQVLDFLTNLAQRSKAQGKRELQELKDFCKTHYNLTALELWDLTFYSEKQKQHLYAINDEELRPYFPEERVLNGLFELIKRIFHIRAVERHGVETWHKDVRFFDLIDDTNEVRGSFYLDLYAREHKRGGAWMDDCIGRRKTIDGNLQKPVAYLTCNFNRPLGDQPALFTHDEVTTLFHEFGHGLHHMLTKIDVADVAGINGVPWDAVELPSQFMENWCWEEEALQFISGHYQTNEPLPKEKLTQLLKAKNFQAAMFVLRQLEFALFDFRLHHTFDANKSNQVLDTLHQVKAEVAVVPTVDWGRMPHSFSHIFAGGYAAGYYSYLWAEVLSADAYSRFEEEGIFNAQTGQSFLDEILTKGGSEEPMKLFKNFRGREPQLDALLRHKGIAN
>NZ_LS483485.1|WP_005700308.1|1762509_1762875_-|YbaN-family-protein
MKYFYIGLGFLFLIIGLIGIVLPILPTTPFLLLTVFFFAKGSERVHNWFVGTKIYQNHLKDFHEQRALTKKTKMAILTFSTTMLLIGFYFTPSIIGKSLIIAVLLIKYWFFFFWIKTLEEE
>NZ_LS483485.1|WP_050326287.1|1760902_1762471_-|peptide-ABC-transporter-substrate-binding-protein
MPVAHFPLSAFRLFPFKSVVLFCSVFALNACDKKPQEPVTPPPTIETVQLQLISSQGNRQLLVRGVYSDLVLNPSQAVNAEQFAFLRDLFEGLVIYDQRGNVIPAVAESWQTTDNKTWKFSLRQDAKWSNGEPVTAQQFVASWQALVTSNSPLRHYLAYINLANAESVLKGKLPADKLGISAENDRTLRLTLDKATPYLPQMLVHISLLPQYLAPHEGIVTNGAYQVAGQENHFIHLEKNPHYWAQDKVAFKHVDYQKIASQQDPIALDLVINPSKTEQAQYFPQLCTYFYAFNMKQPKLAQSSVRKALSMMAPSRNMNNEGKNFIYLSDNFLPISMQTVESHWEQTPMEQLLSQSKISEKAPLKLTLSYDQTELQSKIAQSLIRMWSQSDMIRIIGEGMPRQKLLENIAKGDFQIARSGWCADYNDPAAFLSLFYSHSPDNKSGYHNEEVDRLFEQSLQLMPSAERTTLYSRIEQILQQEKVVLPLYQTTVPIYINPTINGYYLSNPTEVIYSKDLFRKIQ
>NZ_LS483485.1|WP_005700312.1|1760066_1760864_+|hypothetical-protein
MLKTLSKVISSSISMAFLVVLGWSVAYAYGWGQSYFYGFPWWYVDVGSGNVARSLGYVIWATIILLLTYLIGLFGLKKVKPYMSERCVNLLRTYILCTIFFIPIPVACILLVGKLNSIFAIVYIITTFIFTLLFKNYFRNHISTISIHVVIRFFHRNKSYVMLFMYCYFVIFGFIMGYVRPNFKIIFDSMEVEKQSYYVLAKYSDTFILSRSIRATNGDFYIYKMNPNSICHIKVVDIRKLGIDKMAPKEIELKEVKAEEANTEL
>NZ_LS483485.1|WP_005700313.1|1758296_1758950_+|GTP-cyclohydrolase-II
MAKIELVAQANLPTEFGLFKIVGFEFPDSKKEHVALVLGDISNGDEPVLARIHSECLTGDALHSLKCDCGFQLAAALRQINQEGRGVLIYHREEGRGIGLINKIRAYSLQDQGMDTIEANLALGFAADERNFSVCADIFDLLGVKKIRLLTNNPEKIETMKQAGINVVERVPLNVGENRYNTAYLDTKAKKMGHFIVHNGEQHLMECPYCQEEVPKK
>NZ_LS483485.1|WP_111299786.1|1770258_1771884_+|sulfatase-like-hydrolase/transferase
MFKKFLSYLNSRIFWIWLLFFSFITLIISPENSAYYGIFVIYIIYYLIFSFNQKIFWLFITFVVITLSLYQPIYSSYGNLNSGVVAAFFETNPAESFEFLGKLKIDQFILPFLFSLSAYILYRLREQANPQREITEKDIKYKKILNITLISVTIFSIIWIPTKFHFENSSKEQVDSHWTLANSPVNLISFYANIIDSITDYYNDKKDLETAKDVLPPWHIISTQPKYKNYVLIIGESARKDYMSTYGFKLPTTPFLDKTNGYINAGYVSAAPATYHSLLNTLHFKPKEKGKKDYSYNIISLAKVAGIKTFWLSNQGTIGKYDTLASRLGIGADFHYFTKKGGFITNNADDFKLLEELKIKFKEKAYENDTRLFVIHLMGSHRNFCQRITDKEKKLEFINESLSCYVNTILKTDKLIEEIVNVLKEQNEPYSLIYFSDHGLSHVNKENKKEVDLDFGEEHKQNFEVPFVKISSDDTSREVVNVKRSAFNFIYGFSQWLGIETKELNQEYNFFSNKNDENIKVFNFKENIPYSTLKNDDIPNL
>NZ_LS483485.1|WP_111299784.1|1772116_1772593_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE
MTERFTQYIPNENAMCVFGEKLIKAICQVSNNKSVALYLNGDLGAGKTTLSRGMIQGLGYSDNVKSPTYTLVEEYKIGGKIIYHFDLYRLADPEELEFMGIRDYFAENTICLIEWAEKGAGLLASADLLVNIAYAENARNIELLAESETGRQIIQQLN
>NZ_LS483485.1|WP_111299782.1|1772606_1774097_+|N-acetylmuramoyl-L-alanine-amidase
MKAQNIMRFILMHGLLFFAVLAFADNTWTIAIDPGHGGKDPGAIGRNLKIYEKNVTLSIAKELKALLDKDPHFRAVLTRNGDYYISVPQRSEIARKYKANYLVSIHADSSETPNLRGASVWVLSNRRANDEMGQWLEDHEKRSELLGGAGSVLASHNEKYLDQTVLDLQFGHSQRVGYELGNIVLRHFSQIASLSRPTPRHASLGVLRSPDIPSILVETGFLSNQEEELKLSTPAYRKRIAKAIYNGLAEYRRKNVKDEPKVAIADKNEKTSEKSTALEVKDSGIRHTVKSGEGLGKLAEKYHVSTADIIALNKLKRKALWGGETIKIPDNGKNIPTIEDKSVKTKENNIVEVKDSGVRHKVKRGETLGKLAEKYKVSVNDILTLNKLKRKELLIGENLKIPAIAKAETSNKTEKGKETETPKPVDKSPKTQGKTKPEVKEVVPKFHTVKKNETLYSIAREYKIAPNKLLKLNPQLKNGKVLSGQKIKLTEDQGKK
>NZ_LS483485.1|WP_083015768.1|1774096_1775944_+|DNA-mismatch-repair-endonuclease-MutL
MTIRVLSPQLANQIAAGEVVERPASVVKELVENSLDAGADKIQIDIENGGAGLIRIRDNGIGIAKEELALALARHATSKIADLADLEAILSLGFRGEALASISSVSRLTLTSRTAEQHEAWQVYAQGRDMETTIQPASHPIGTTVEVANLFFNTPARRKFLRSEKTEFSHIDEVIRRIALAKFNISFTLTHNGKVLRQYKSAMTNEQKLKRVATICGDDFIQNALQIDWKHDDLHLSGWVALPHFNRPQNDLNYCYVNGRMVRDKIITHAIRQAYAEYLSNDQYPAFVLFIDLNPNDVDVNVHPTKHEVRFHQSRLVHDFITQGISHALTSESLDFSATETERKIQEPMGLWEVSSKPNRSAAGPNMFTQPSTYSTGYRVEKQPSEDTYHSSQKHRQNPPHFNRDNITPSVLDAHKHLWMDSTAPSRSKITISEDSKPQSTCLHALALVGNHALLLQQEQHFYLLSLSRLQRLKLKLNLTLTATSQPLLIPVIFRLSETQWQAWQQQKAWFTQVGFDFLAEDAQRKITLQKVSAHLRRQNLQQLIIALLNEPVENLSEFLTALLAQLDFPPIQVLADAVTMLTEIEQLLNKQSHIQLSDLFLEINWQPYLTQLAD
>NZ_LS483485.1|WP_111300450.1|1775949_1776903_+|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA
MQHSEHKPTAIFLMGPTASGKTDLAIQLRQQLPVEVISVDSALIYRGMDIGTAKPTAEELALAPHRLIDICDPAESYSAMNFCHDALREMQDITAQGKIPLLVGGTMLYYKALLEGLSPLPSADEKVRSEIETKAMQIGWSGLHQELAKIDPISAQRINPNDSQRINRALEVFYLTGKTLTELTAQKGEALPYDILQFAIAPEQREVLHLRIEQRFHKMIELGFQQEVEKLYQRSDLNENLPSIRSVGYRQMWEYLRGDYDHKEMIFRGICATRQLAKRQITWLRGWKSPIQWLDSLHPTQALEKVLVSVNSLSDKQ
>NZ_LS483485.1|WP_005702982.1|1777029_1777332_+|RNA-chaperone-Hfq
MAKGQSLQDPYLNALRRERIPVSIYLVNGIKLQGQIESFDQFVILLKNTVNQMVYKHAISTVVPARSVAHHNANQQQQHQQGQQQEAPSSVETNTDAQTE
>NZ_LS483485.1|WP_172452426.1|1777415_1778729_+|GTPase-HflX
MPENSTQTSDHTINNAIIVHCFFEQSKNTDDLTEFQLLAKSANVHILNVITATRSTPQAKYFIGSGKAEEIADAVRQYNADLILVNHSLTPAQARNLEALCDCRVVDRNGLILDIFAQRARSHEGKLQVELAQLKHLSTRLVRRKTGLDQQKGAVGLRGPGETQLETDRRLIKVRINQLQSRLEKVDKQRNQNRQTRQKADIPTISLVGYTNAGKSTLFNLITDANVYAADQLFATLDPTLRRLTLQDVGTTILADTVGFLRDLPHDLISAFKSTLQETTEASLLLHVIDCADNRKLENIEAVNQVLEEIGAQEVPRLLVYNKIDQLENVVPHIEYDEKHLPSAVYISANSGSGLDLLLEAIRLRLTEHILNLQIRLPPSDGKLRHAFYQLNCVEKEEINEQGEFLLSIRLEKTEWLKLVKRFTQLTPFNPIQPDEN
>NZ_LS483485.1|WP_111299780.1|1778725_1779685_-|sigma-54-interacting-transcriptional-regulator
MTTSKNTDPFAQIVSKNPRMQDVIEKAKKFALLDVPLLIQGETGTGKDVIAKACHDFSERRDHAFLAVNCAGIPGEDAETEMFGRRNKDGEFIGFFEYADGGTVLLDGVEELSLTLQAKLLRFLSDGTFRRVGEEEERYANVRVICTSQQPLQHYVEQGKMRSDLFHRLNVLSLNLPLLRERKEDLALLSHQLIQEISEKLGIFPPHFDENVLRYLQEYPWPGNIRELYNALYRACSLCQNNQLRIEDLGLASQIPHSQDIDQFITEGDTLDEMVGRFEAAVLNKFYAKYPSSRKLATRLGVSHTAIANKLRQYGIGKS
>NZ_LS483485.1|WP_111299778.1|1779781_1780876_-|TIGR01620-family-protein
MEKKVFTQNESDMNEDLNAQSAFIAKQEFHEEQAVPDTEDENGIFEGELLEQQFEQSLQPKPRWWKKILGGVSLLFFVASVAQSVQWLVDAWQQNQWIYFAFSLVACAVILLGVSAIAGEWRRLAKLRHRAEIQTQSQQLLKSAVNFKDVFSSAEHQQAVSLCQEVTKLVHIDGQNPDFMQWQKQIHEAYSAREILHLFSQNVLQPVDKQAKKLITKASTESAALVAISPLELVDIFFIAWRNIRLINQIARIYGIELGYFSRIRLLRMVLVNMAFAGVTELIQDLGVNWLSQDLTAKLSARAAQGIGVGILTARLGIKAMEFGRPLAFQSNEKPRLSQLHKELLSHLSNTVFDQVKFKQKNKV
>NZ_LS483485.1|WP_111299776.1|1780886_1782293_-|YcjX-family-protein
MLNHLQKELNELVNRGLDRTLRIAVTGLSRSGKTAFITSLMNQMLHINRVDNGHLPLFDAARQHRILAVQRVPQLDLSIPRFDYEGNLNALSQEPPIWPQSTRGVSETRLAIRYQRSNGLLRHLKEKGTLYLDIFDYPGEWLLDLPLLDLGFEQWSLELQRQLNGTHAELAQTWLNKVKKIKLTDSADEDILAHLAKDYTDYLWQCKKQGLHFIQPGRFVLPGELEGAPALQFFPLLHLNASQWQQLKREAKSESYFAVLTKRYDYYRQHIVKGFYENYFETFDRQVILADCLTPLNHSRQAFNDMQQALQQLFRNFHYGKRHLLNRLFSPKIDKLMFIATKADHITTDQLPNLIGLMRQLVQEGGRYVEFADIVTDYTAIASIRATQQVVVNQNGKQFKALQGIRSSDKQKVTLYPGSVPGRLPSADFWQNQKFEFDQFEPRRLEQGENIPHLRMDAVLQFLLGDKL

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Crispr_ID: NZ_LS483485_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483485_2

2001339-2001979

TypeI

Consensus_repeat	Method
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	CRISPRCasFinder
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	CRT
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	PILER-CR

9 spacers

cas2,cas1,cas4,cas7,cas8c,cas5

The CRISPR arrays of NZ_LS483485_2

>merge|NZ_LS483485|2|2001339-2001979|CRISPRCasFinder,CRT,PILER-CR
GACAAAATATATACTCACCCGAAGGCGGCTGCCGCCTTTTTGGTAGGTTTAAAAATAAAAATGAGTGTTTCAACACACAGCCACCCGAAGGTGGCTGCCCAGAGCAGTTACGAAAATTAAGCTGCGGAATCAAAGTTTCAACACACAGCCACCCGAAGGTGGCTGCACAACGAGCAGGCGTGGGCGGAGAACTATTTGACGTTTCAACACACAGCCACCCGAAGGTGGCTGCATTTATGGTGCGATTACATTAATTGTTGTTCCTGTTTCAACACACAGCCACCCGAAGGTGGCTGCTTTCAAGTTGTTGTGCGGTTAATACCGCACTATTGTTTCAACACACAGCCACCCGAAGGTGGCTGCGTATCATTGTTTGTAGATAATTCTTGCTTACAAATGTTTCAACACACAGCCACCCGAAGGTGGCTGCGCAAAACTTTTAGAACAAAACGGCTTGCCGGTAACCGCGGTTTCAACACACAGCCACCCGAAGGTGGCTGCGCAATCTGACCGCACTTTTGCAGAAAAACCTGTTGCGGTTTCAACACACAGCCACCCGAAGGTGGCTGCGCGAACCATTTACGCATCAGCATCGGGTTGCCGGAAGCGGTTTCAACACACAGCCACCCGAAGGTGGCTGC

>NZ_LS483485|2|2|2001339-2001979|CRISPRCasFinder
GACAAAATATATACTCACCCGAAGGCGGCTGC	CGCCTTTTTGGTAGGTTTAAAAATAAAAATGAGT
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	CCAGAGCAGTTACGAAAATTAAGCTGCGGAATCAAA
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	ACAACGAGCAGGCGTGGGCGGAGAACTATTTGAC
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	ATTTATGGTGCGATTACATTAATTGTTGTTCCT
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	TTTCAAGTTGTTGTGCGGTTAATACCGCACTATT
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	GTATCATTGTTTGTAGATAATTCTTGCTTACAAAT
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	GCAAAACTTTTAGAACAAAACGGCTTGCCGGTAACCGCG
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	GCAATCTGACCGCACTTTTGCAGAAAAACCTGTTGCG
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	GCGAACCATTTACGCATCAGCATCGGGTTGCCGGAAGCG
GTTTCAACACACAGCCACCCGAAGGTGGCTGC

>NZ_LS483485|2|1|2001339-2001979|CRT
GACAAAATATATACTCACCCGAAGGCGGCTGC	CGCCTTTTTGGTAGGTTTAAAAATAAAAATGAGT
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	CCAGAGCAGTTACGAAAATTAAGCTGCGGAATCAAA
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	ACAACGAGCAGGCGTGGGCGGAGAACTATTTGAC
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	ATTTATGGTGCGATTACATTAATTGTTGTTCCT
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	TTTCAAGTTGTTGTGCGGTTAATACCGCACTATT
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	GTATCATTGTTTGTAGATAATTCTTGCTTACAAAT
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	GCAAAACTTTTAGAACAAAACGGCTTGCCGGTAACCGCG
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	GCAATCTGACCGCACTTTTGCAGAAAAACCTGTTGCG
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	GCGAACCATTTACGCATCAGCATCGGGTTGCCGGAAGCG
GTTTCAACACACAGCCACCCGAAGGTGGCTGC

>NZ_LS483485|2|1|2001405-2001979|PILER-CR
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	CCAGAGCAGTTACGAAAATTAAGCTGCGGAATCAAA
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	ACAACGAGCAGGCGTGGGCGGAGAACTATTTGAC
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	ATTTATGGTGCGATTACATTAATTGTTGTTCCT
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	TTTCAAGTTGTTGTGCGGTTAATACCGCACTATT
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	GTATCATTGTTTGTAGATAATTCTTGCTTACAAAT
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	GCAAAACTTTTAGAACAAAACGGCTTGCCGGTAACCGCG
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	GCAATCTGACCGCACTTTTGCAGAAAAACCTGTTGCG
GTTTCAACACACAGCCACCCGAAGGTGGCTGC	GCGAACCATTTACGCATCAGCATCGGGTTGCCGGAAGCG
GTTTCAACACACAGCCACCCGAAGGTGGCTGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483485.1\|WP_005703645.1\|1984045_1986412_+\|TonB-dependent-receptor-plug-domain-containing-protein	unknown	unknown	gnl\|CDD\|369481
NZ_LS483485.1\|WP_109843271.1\|1998697_1999489_+\|endonuclease/exonuclease/phosphatase-family-protein	unknown	unknown	gnl\|CDD\|197313
NZ_LS483485.1\|WP_111300982.1\|2008886_2010224_-\|DNA-double-strand-break-repair-nuclease-NurA	unknown	unknown	unknown
NZ_LS483485.1\|WP_111300970.1\|2002172_2002466_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_LS483485.1\|WP_050332750.1\|1989659_1990391_-\|AzlC-family-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|129446
NZ_LS483485.1\|WP_111300966.1\|1991592_1993866_+\|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase	unknown	unknown	gnl\|CDD\|235367
NZ_LS483485.1\|WP_111300972.1\|2004195_2004708_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483485.1\|WP_109843269.1\|2002540_2003554_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_LS483485.1\|WP_111711286.1\|1994914_1998688_+\|4-alpha-glucanotransferase	unknown	unknown	gnl\|CDD\|340853
NZ_LS483485.1\|WP_111300976.1\|2005420_2006287_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl\|CDD\|377458
NZ_LS483485.1\|WP_109063571.1\|1999499_2001164_+\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|131058
NZ_LS483485.1\|WP_111711285.1\|1989330_1989663_-\|AzlD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224601
NZ_LS483485.1\|WP_109843315.1\|1994002_1994716_-\|UTRA-domain-containing-protein	unknown	unknown	gnl\|CDD\|274116
NZ_LS483485.1\|WP_070613733.1\|2010236_2012282_-\|DUF87-domain-containing-protein	unknown	unknown	gnl\|CDD\|223510
NZ_LS483485.1\|WP_109129741.1\|1990395_1991328_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176132
NZ_LS483485.1\|WP_111711309.1\|1986489_1989264_+\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NZ_LS483485.1\|WP_111711287.1\|2006298_2008089_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl\|CDD\|378245
NZ_LS483485.1\|WP_111300980.1\|2008085_2008763_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187534
NZ_LS483485.1\|WP_070613732.1\|2012285_2013278_-\|site-specific-DNA-methyltransferase	unknown	unknown	gnl\|CDD\|334588
NZ_LS483485.1\|WP_111300974.1\|2004754_2005405_-\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|273040

Protein	Function_ID	Function_description	E-value
NZ_LS483485.1\|WP_005703645.1\|1984045_1986412_+\|TonB-dependent-receptor-plug-domain-containing-protein	gnl\|CDD\|369481	pfam07715, Plug, TonB-dependent Receptor Plug Domain. The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.	9.2007e-09
NZ_LS483485.1\|WP_109843271.1\|1998697_1999489_+\|endonuclease/exonuclease/phosphatase-family-protein	gnl\|CDD\|197313	cd09079, RgfB-like, Streptococcus agalactiae RgfB, part of a putative two component signal transduction system, and related proteins. This family includes Streptococcus agalactiae RgfB (for regulator of fibrinogen binding) and related proteins. The function of RgfB is unknown. It is part of a putative two component signal transduction system designated rgfBDAC (the rgf locus was identified in a screen for mutants of Streptococcus agalactiae with altered binding to fibrinogen). RgfA,-C,and -D do not belong to this superfamily: rgfA encodes a putative response regulator, and rgfC, a putative histidine kinase. All four genes are co-transcribed, and may be involved in regulating expression of bacterial cell surface components. This family belongs to the large EEP (exonuclease/endonuclease/phosphatase) superfamily that contains functionally diverse enzymes that share a common catalytic mechanism of cleaving phosphodiester bonds.	4.62489e-124
NZ_LS483485.1\|WP_111300970.1\|2002172_2002466_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.66556e-32
NZ_LS483485.1\|WP_050332750.1\|1989659_1990391_-\|AzlC-family-ABC-transporter-permease	gnl\|CDD\|129446	TIGR00346, Uncharacterized_membrane_protein_HI_1738, 4-azaleucine resistance probable transporter AzlC. Overexpression of this gene results in resistance to a leucine analog, 4-azaleucine. The protein has 5 potential transmembrane motifs. It has been inferred, but not experimentally demonstrated, to be part of a branched-chain amino acid transport system. Commonly found in association with azlD. [Transport and binding proteins, Amino acids, peptides and amines].	5.2473e-97
NZ_LS483485.1\|WP_111300966.1\|1991592_1993866_+\|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase	gnl\|CDD\|235367	PRK05222, PRK05222, 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional.	0
NZ_LS483485.1\|WP_109843269.1\|2002540_2003554_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_LS483485.1\|WP_111711286.1\|1994914_1998688_+\|4-alpha-glucanotransferase	gnl\|CDD\|340853	cd04300, GT35_Glycogen_Phosphorylase, glycogen phosphorylase and similar proteins. This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	0
NZ_LS483485.1\|WP_111300976.1\|2005420_2006287_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	2.50777e-153
NZ_LS483485.1\|WP_109063571.1\|1999499_2001164_+\|PTS-transporter-subunit-EIIC	gnl\|CDD\|131058	TIGR02003, PTS_system_glucose-specific_IIBC_component, PTS system, IIBC component. This model represents a family of fused B and C components of PTS enzyme II. This clade is a member of a larger family which contains enzyme II's specific for a variety of sugars including glucose (TIGR02002) and N-acetylglucosamine (TIGR01998). None of the members of this clade have been experimentally characterized. This clade includes sequences from Streptococcus and Enterococcus which also include a C-terminal A domain as well as Bacillus and Clostridium which do not. In nearly all cases, these species also contain an authentic glucose-specific PTS transporter. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
NZ_LS483485.1\|WP_111711285.1\|1989330_1989663_-\|AzlD-domain-containing-protein	gnl\|CDD\|224601	COG1687, AzlD, Predicted branched-chain amino acid permeases (azaleucine resistance) [Amino acid transport and metabolism].	3.82792e-38
NZ_LS483485.1\|WP_109843315.1\|1994002_1994716_-\|UTRA-domain-containing-protein	gnl\|CDD\|274116	TIGR02404, Trehalose_operon_transcriptional_repressor, trehalose operon repressor, B. subtilis-type. This family consists of repressors of the GntR family typically associated with trehalose utilization operons. Trehalose is imported as trehalose-6-phosphate and then hydrolyzed by alpha,alpha-phosphotrehalase to glucose and glucose-6-P. This family includes repressors mostly from Gram-positive lineages and does not include the TreR from E. coli. [Regulatory functions, DNA interactions].	1.29627e-60
NZ_LS483485.1\|WP_070613733.1\|2010236_2012282_-\|DUF87-domain-containing-protein	gnl\|CDD\|223510	COG0433, COG0433, HerA helicase [Replication, recombination, and repair].	4.22663e-09
NZ_LS483485.1\|WP_109129741.1\|1990395_1991328_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176132	cd08441, PBP2_MetR, The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold. MetR, a member of the LysR family, is a positive regulator for the metA, metE, metF, and metH genes. The sulfur-containing amino acid methionine is the universal initiator of protein synthesis in all known organisms and its derivative S-adenosylmethionine (SAM) and autoinducer-2 (AI-2) are involved in various cellular processes. SAM plays a central role as methyl donor in methylation reactions, which are essential for the biosynthesis of phospholipids, proteins, DNA and RNA. The interspecies signaling molecule AI-2 is involved in cell-cell communication process (quorum sensing) and gene regulation in bacteria. Although methionine biosynthetic enzymes and metabolic pathways are well conserved in bacteria, the regulation of methionine biosynthesis involves various regulatory mechanisms. In Escherichia coli and Salmonella enterica serovar Typhimurium, MetJ and MetR regulate the expression of methionine biosynthetic genes. The MetJ repressor negatively regulates the E. coli met genes, except for metH. Several of these genes are also under the positive control of MetR with homocysteine as a co-inducer. In Bacillus subtilis, the met genes are controlled by S-box termination-antitermination system. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	7.1254e-108
NZ_LS483485.1\|WP_111711309.1\|1986489_1989264_+\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	2.30186e-61
NZ_LS483485.1\|WP_111711287.1\|2006298_2008089_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	0
NZ_LS483485.1\|WP_111300980.1\|2008085_2008763_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	1.3418e-116
NZ_LS483485.1\|WP_070613732.1\|2012285_2013278_-\|site-specific-DNA-methyltransferase	gnl\|CDD\|334588	pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.	3.1185e-32
NZ_LS483485.1\|WP_111300974.1\|2004754_2005405_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	1.08667e-44

>NZ_LS483485.1|WP_109063571.1|1999499_2001164_+|PTS-transporter-subunit-EIIC
MKKLLSFEFWQKFGKCLMVVIAVMPAAGLMVSIGNSLPLISDAEWLARVGNIIAQIGWGIIGNLHLLFALAIGGSWANERAGGAFAAGLAFILINLITGHFFGVKIEMLTDPNAHVSTILAGDIPVANYFVNILGQPALNMGVFVGIIAGFVGATTFNSYYNFRKLPEVLTFFNGKRFVPFVVIYRSVLVALILAVFWPVVQTGINHFGEWIANSQDSAPILAPFVYGTLERLLLPFGLHHMLTIPMNYTSLGGTYEFLTGMQQGKQVFGQDPLWLAWISDLINLKDAGNMTQYNELLSTVTPARFKVGQMIGSSGILMGITLAMYVNVDTDKKTIYKGIFLSSALAVFLTGVTEPIEYMFMFVALPLYLVYAAIQGCAFAMADIVNLRVHSFGNIEFLTRTPMAIKAGIGMDLINFIWVSGVFAVAAFLIANFMIKKLNLATAGRNGNYDAKGSDEAPTEEKKVANASAQVVQIINLLGGRNNIAEVDACMTRLRITVHNPELVGDAAAWKQAGAMGFIVKGTGIQAIYGPKADVLKSDIQDLLSSGVEIPKM
>NZ_LS483485.1|WP_109843271.1|1998697_1999489_+|endonuclease/exonuclease/phosphatase-family-protein
MKLLTLNVHAWLEDNQAEKIDIIADTIVEKGYDIVALQEVNQLMSAPAISQALKQDNYGVVLLNKINQRATQKYSLFWSNSHIGYDKYDEGIAFLTRLPVYEVDAFYCSQHQRLDSILSRKILGLTVEYQGQLVDCYSCHINLPNCAGENQLDNIRNIVERSQSQNLKILMGDFNTDAISDPDAYQKIKSLGLLDTFEMAEQKDSGITVEKAIDGWKGHSEEKRLDYIFLNQAKRVLSSQVVFNGKNKPVVSDHFGLEIELTL
>NZ_LS483485.1|WP_111711286.1|1994914_1998688_+|4-alpha-glucanotransferase
MLTRSSGVLMHITSLPNAFGIGSFGQSAYDFVDFLVETKQSYWQILPLTTTSYGDSPYQSFSAIAGNTHLIDFALLTQMGLLQETDYASVNFGDDPTKVDYERIFYARRPILEIAVKHFLADKKRQADFKNFEKNNRTWLEDYAEFMAIKEHFGNKALQEWEDKLVVARKPKTLAKYRTMLKEQIQYFKVTQYFFFQQWLALKNYANQRGIKIIGDMPIYVAEDSVEVWTMPELFQLDKECKPLFVAGVPADQFSATGQLWGNPLYDWPEHKKQGYAWWIHRIEESFKIYDVLRIDHFKGFSDYWQVDGKADIAKYGTWQPGPGYDLFKAVKAQLGDLPIIAENLGNIDEKAEKLLTDCGYPGMKILQFGFENVSGESLDSPHYCIPHCIAYTGTHDNDVINGWYADLSTKQQQYINAYTHRATDESVCQAMIRQLFATVSNTVIATMQDILDLPASSRMNLPSTIGGNWEWRMQESDLTKAKKDFLTQITMLYGRANKEQVMIKFSEFVQQTTNKKLEKLSDHAIYVQLLNYVKTLAANKGKNTAKRKIYYISAEFLIGKLLSNNLINLGVYQEIKDELAQAGKSLSHIEDIEPEPSLGNGGLGRLASCFIDSMSTLGLNAEGVGLNYHCGLFKQVFKNNEQHAEPNNWIEKESWLIPTDIHYEVPFKDFTLTSKLDRIDILGYKKDTQNYLNLFDIESINHKLIKKGITFDKTKIKENLTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLLIDEAIERGSNLHDLADYAYVQINDTHPSMVIPELIRLLTEKHRIKFAEAVEIVRNMVGYTNHTILAEALEKWPLAYLEEVVPHLVKIIKKLNKLVHKEYPNPDVQIIDKQKRVHMAHMDIHFSNSVNGVAALHTEILKNSELKAFYEIYPEKFNNKTNGITFRRWLEFSNQELAAYIKQLIGDGYLHDATQLEKLLTFKDDKKVHQKLAEIKFRNKLALKTYLKENKGIELDENSIIDTQIKRFHEYKRQQMNALYVIHKYLEIKAGKLPKRKITVIFGGKAAPAYVIAQDIIHLILCLSELINNDPDVNHYLNVHLVENYNVSVAEKLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAELAGAKNIYTFGKDSESIIKLYETAGYVSKDYYKKDKHIKRAVDFILDSTLVKLGNQKRLKRLHDELLNKDWFMTLIDFDAYVTAKEQILADYEAQDSWNEKVIHNIAKAGFFSSDRTIAQYNTDIWHCED
>NZ_LS483485.1|WP_109843315.1|1994002_1994716_-|UTRA-domain-containing-protein
MSKYKAVYNDIKSKITDGILPPKQELPSESELMQEYGFSKDTIRKALSLLEMDGYIQKQQGRTSIVLEHNLSTPQQLSEIKTVGELNRPLTHQVKTTLTSLYIVQGEEELMRIFNVNDQIDFYRIGRVREIDGEAVEYEVSYFDRRIVPFINREIAEQSIYHYLESELGLKISYSQREIVFRYANEEEKSTMDLGEYNMVVNVTSTTYLADGRPFQYGSISYRPDKITFASTAKRHV
>NZ_LS483485.1|WP_111300966.1|1991592_1993866_+|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase
MTIFHLAGFPRVGAKRELKFAQERYWRGEIAEADLLDIAKKLREINWQHQANANADFVAVADFTFYDHILDLQVATGAIPTRFGFDSQNLTLDQYFQLARGNKTQFAIEMTKWFDTNYHYLVPEFHKDTQFKANPAHYVQQIREAKALGHNVKPTIVGPLTFLWLGKEKGATFNRFDLLNKLVPVYVDILNALSSEGVEYIQIDEPALTLDLPAEWVAAYKEVYATFAAQVNAKLLLATYFGSVSEHADLLKALPIAGLHIDLVRAPEQLSAFADYDKILSVGVIDGRNIWRANLNQVLDVVEPLKAKLGERLWIAPSCSLLHTPYDLAVEIQLQANKPELYQWLAFTLQKIQELRVIKTALEQGREAVQAELDASQAAADARKNSREIHRTCVAERLANLPKNADQRKSPFAERIKLQNTWLNLPLLPTTNIGSFPQTTEIRHARAAFKKGALSLADYEAAMKKEIEFVVREQEKLDLDVLVHGEAERNDMVEYFGELLDGFAFTKFGWVQSYGSRCVKPPVIYGDVTRPEPMTVRWSQYSQSLTNKVMKGMLTGPVTILQWSFVRNDIPRSTVCKQIAVALSDEVLDLEKAGIKVIQIDEPAIREGLPLKRADWDAYLQWAGEAFRLSSMGCKDDTQIHTHMCYSEFNDILPAIAALDADVITIETSRSDMELLTAFGDFKYPNDIGPGVYDIHSPRVPTAEEIEHLLRKALQVVPKERLWVNPDCGLKTRGWPETIAALKVMVDVTKKLRAELA
>NZ_LS483485.1|WP_109129741.1|1990395_1991328_-|LysR-family-transcriptional-regulator
MKPIFLELRHLKTLLALKETGSVSLAAKRVYLTQSALSHQIKLLEDQYGLPLFERKTQPLHFTPAGERLIQLANDILPKVIEAERDLARVKQGEAGELRIAVECHTCFDWLMPAMDLFRQHWPLVELDIVSGFHTDAVGLLLSHRADWAVVQEVEETPGIVYKPLFSYEMVGLCAKDHPLAAKDVWQAEDFIDQTLITYPVPDDMLDLLRKVLHPKGVNPTRRTSELTIAIIQLVASKRGVAALPFWAAKPYLDRGYIVARKITEQGLHSNLYAATRELDSQIAFVDDFYETVKAQSFSTLPELSILEEI
>NZ_LS483485.1|WP_050332750.1|1989659_1990391_-|AzlC-family-ABC-transporter-permease
MSDVKTNSHPIWAAAKAALPYSAPMLAGFLFLGVAYGIYMKALGFSFWYPVLMALLIYGGSVEFIIAGALSLAFAPLNALLITLMVSGRQLFYSISMLEKYGKSLGKKRPYLIATLVDESFSLNYMAKVPSHIDRGWYMFFVSFYLHMYWMIGAGLGNLFGNIIPFDLKGIEFAMTALFLVIFAENWAQEKSHESSLLGLAIAAISLIVFGREYFLLPTLIGIWTVLTFRRPKLSSRLERIEE
>NZ_LS483485.1|WP_111711285.1|1989330_1989663_-|AzlD-domain-containing-protein
MTLTEQIITIGIAVLGVQFTRWLPFWVFSANRPIPEYIRYLGKVLPAAMFGMLVVYCYKNVDVFSGFHGVPEFLSGVIVVALHLWKRNMFLSIAAGTMLYMFLVQRVLVA
>NZ_LS483485.1|WP_111711309.1|1986489_1989264_+|insulinase-family-protein
MKKLTALFVLLCSFRLVIACQAGIDPDALAFDPNIKHGKLTNGLQYYILNNRDPKDRVYIRLVVNAGSMHEDDDQKGIAHLVEHMAFNGSKKYPENTIINALEKLGMKFARDINAFTDFENTVYTLNLDGNSPQKLSLAFDVINEWMNHLTILPKDLDGERGVVQEEWRRRLSPMLRLGDKKSAIEMAGSRYVLRDPIGDMNIIRHISRDRVADFYHKWYRPDNMSLIVVGDIDTHKITQLISQQLDKPSSHTQRPLDKIDFSIPLIHHWRVASIAEQGTNIPALELSFFEEDKQKETITDYKQDLIQQIVTRLVNLRLQKWEENQNNWLDSANFYRSHLGKQTLQSVFSLQLADTNYLKNITALFAFIAEIKQHGFTADELNSEIARLHNLNEKQQNIRPGSLKIANDLIAIAANHQIMLSAKERYNLNRRFLNEIKVTDLNVTFNQMLALNAKLLLITQLLPEKKLPFDATYIEQRWNQAMRSDQNQWENKKHIVKQPHFEFKDGSLVLEKHWDKGNIDEFRLSNGAKLIYHYSNKTPNQVHFRAVTSGGLRSVPNQDYHLLRTAITLVDDTGTGELTQADVSNLFGQSPLVLATVIDDDKQGFTGVAKPQDLSRLLTLFRLKLQSAPVSNNVLQKYHRETQDYFKQIDAETKFMQAISYLRRPNTATVYTQNQNEQLSFTAAQLSQIYQEKILGKTDFTYFIIGDISRSELEKLAKQYLATVEIKTQARAYQPGYIHTPKKAFIMRGLSEPRADVEIYLTAENQWHPEQKYALEILGEIVQEKLRLVLREKVSGIYSVNSWFSQDPHTPQIEGKIAFSCAPNRAEELIKLTHQILDEIIENGIDETLLRKKQAEQQQYIKRQFDSLVSVASMIEDSYWQQGNPQSVYLYQRLEQLADKPHLEALARKVLVKAARFEAILRQ
>NZ_LS483485.1|WP_005703645.1|1984045_1986412_+|TonB-dependent-receptor-plug-domain-containing-protein
MYKKTKIAFFICTALYAQHVLSEEKSTNKSNMLPEIIVYGDSNKSLSSTQAVTSNEMEKIPTTNNNITDYLRSNPHIRYEDSDQNGFQLGEIKPQNISINGADANQTAYFVDNVNVNNDLTVDNEIFDGAMQVVPGISNTQAYFFDASMLSKVEVHDSNISASLGGFMGGAVVAKTKQYNGKDGVSLKYRTTNSGWAKINADSSAKTLLDKIRPDAGGVAEFQPKYHKQTFSIMAEKGLTENLGMVIGYSKRHARIQQNRLIGYAPDVKLDKQNHKRDSDNLLLNFNLAASEKDRFELGFRYSNYKEQKYYATNIDSNVSDYHQALGSTLAWVHSFNSGILTNTLAYDHFKDKRKSSSANVEIVSVFDENFDPLYDYEKGGYGNSSLTQDNIHFSTEFAVDPFNLGFANHSISIGGIYQATHYKFNRPQDVHSKIIQKYPNLSPIETTNVTHQGNAQTRYQNFVFYTEDLIKWKKLELRPGVRIERDDYLQNNNIAPRFVARYKPWEETGFTLGLNRYYGRSFASLKLTNEILKINRDTSRKYQEFHSLKTPYADELSIGFDQEFNNLAFKLNYIHRKNKNRIVLKRDANKVNFYHNGSDFSVEVYTFQMNNIEPWQLGKSYWTSSLGFDWLKTKRADIGRDLDPNELVYLDGKLLTRREMLNKVNSSTEDWITRFGLDMAIPDYNITWSNKVYIKAPIRSYDVLEGDFNDGISRYRSYHYGRHTQWDSSIRWQPTITGNHSIYLQVDILNVLNKTRKSKTVKPISSNDEYGIYTPGREFWLEVGYKF
>NZ_LS483485.1|WP_111300970.1|2002172_2002466_-|CRISPR-associated-endonuclease-Cas2
MLMLITYDISLEDAEGQARLRRVAKLCLDYGVRVQYSVFECDITPDQWVVLKDKLLKTYNPETDSLRFYHLGSKWRRKVEHHGAKPAVDVFKDVLVI
>NZ_LS483485.1|WP_109843269.1|2002540_2003554_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MRKLQNTLYITTQGSYLHKERETLVVEQERKKVAQLPVHSIGHIFCFGNVLVSPFLLGFCGENNVNLAFFTENGRFLGRLQGRQSGNVLLRRAQYRVSEQNPVPIARNIIAAKIQASKRVLQRQIRNYGENAAIQSAVDALNISLRQLKGTAELDVVRGIEGDAAARYFGVFGQLLSEKSGFAFDGRNRRPPRDGVNALLSFVYSILGKDISGALQGMGLDPQVGFLHADRPGRDSLAQDILEEFRAWWADRLVLSLINRGQIKPQDFVTEASGAVSLKADARKLLFQALQAKKQEKIVHPFLGEEVEIGLLPYIQAMLLARHLRGDLAEYPPFLMR
>NZ_LS483485.1|WP_111300972.1|2004195_2004708_-|hypothetical-protein
MVNKNMIKSKKIFRFEDGEINFEAEKFLFKLEVDNTISVANHIQFHPVRSYKNSLKQVLRPIEGIADLFISCIEEKFNNYDDEMNDALIELIENMLHNIISHVDTCKNIIKQLSGEMKSNGIQNEFLNNIELYRSLFAKQINLVKHNSRFIRVIRGRDEKRKEILLLGTI
>NZ_LS483485.1|WP_111300974.1|2004754_2005405_-|CRISPR-associated-protein-Cas4
MTALLTETQGKNQDTRLIPLSALQHYAFCPRQCALIHNEQAWAENYLTAQGKALHERVDSGEPETRRGVRFERTVHVSAEKLGISGVLDLVEVETKTGRLKPVEYKRGKPKPDPMDEIQLCAQGLCLEEMTGQIVSEGALWYMQTRHRVPVAFSDDLRAQTLATIAAVRELLNSGQTPPPNYSKRCKACSLVEICQPELLGKRDRSVGYVAGLFGE
>NZ_LS483485.1|WP_111300976.1|2005420_2006287_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSAIQNRYEFVYFFDVTNGNPNGDPDAGNMPRLDPESSKGLVTDVCLKRKIRNFVEISSENEAGYEIYVKEKSVLNLQNKRAYEALGIESEAKKLPKDEAKARDITAWMCKNFFDIRTFGAVMTTEVNSGQVRGPVQLAFAQSIDPIVPLEISITRMAVTNEKDLEKERTMGRKYIVPYALYRVHGFISANLAAKTGFSDDDLAKLWQALTLMFEHDRSAARGEMAARKLIVFKHDSALGSQPAHKLFDAVKVERVNGESGTPASGFGDYKISVVSDGLNGVSVEELL
>NZ_LS483485.1|WP_111711287.1|2006298_2008089_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MILASLARYYRCLAAETDEMGNPKVPPYGFSEEKIGWILVLDKEGRLKTVVPNLTADKKPQPKLMSVPRPEKRTSGIKPNFLWDKTAYALGVEANKNKAEAKEKPFTLSEKTFDAFKQYHLDLLQNSDDEGLQALCRFLQNWQPAHFAAENLPAEMLDANIAFSLEKPTALIHKREAAQTLWAGSLKSDEALEGLCLISGDTAPIARLHPAIKGVFGGQSSGGSIISFNKEAFASFGKEQGANAPVSEQSAFAYTTALNYLLRQRNQEANNHCLTIGDASTVFWAEADDNATAQAAEGFFAQVFMPPNDEQESVKIFNVLEQIGKGCPLQEIAPELSPNTRFYILGLAPNAARISVRFWLDTTFGQLAENLAQHWQDLALEPCAWKTPPSIWRLLLQTAVLGKSENISPVLAGEMTRAVICGTPYPLSLLSQLITRIRADGDVNGLRVAIMKAVLERRFRKGFIEEGVPMSLNNESPNRAYLLGRLFAVLERIQYQALGELNAGIADRYYGSASAVPFSVFPRLLSGAKHHLSRLRKDKAGMAVNLDKDLGEIIAKLPETFPRHLSIDEQGRFAIGYYHQKQSYFAKKETAETIEN
>NZ_LS483485.1|WP_111300980.1|2008085_2008763_-|type-I-C-CRISPR-associated-protein-Cas5
MANQIRLHIWGDYACFTRPEMKVERVSYDVITPSAARGILAAVHWKPAIRWVIDRIYVLKPIRFDSVRRNELGGKISAGKVSGAMKRKSVADLYTLIEDDRQQRAATVLKDVAYVIEAHAVLTAKAGADETVTKHIEMFKRRAKKGQCFQQPCLGVREFPADFALIDEDEPLPPSVLSENEANRDLGWMLHDIDFDHGNTPYFFRAQMKDGVIDVPPFYAEEVKA
>NZ_LS483485.1|WP_111300982.1|2008886_2010224_-|DNA-double-strand-break-repair-nuclease-NurA
MSYSSVGKKPFEKASKSSHHHIINDEVVQSALSNFYIPDVLPEVSISSLTVPHNSCEHSLKHVVAIDGGYTEIPLKIGYPSASLHFFQFGALYFKTEDLKNMKQQKHIAPEDMQKLRNIARIKLPLCTKGVKRKDCSSLTSSVRRSLFEFLKSENMAENSSLLDTLAWFVFHRYKHNRGVEEKHWNLSSHPCNSDTRNVLLEENEMQNYTFSSNDGDIYLSDIFRLHEIIDDDLGASGISGYVTGLVEHLMLLHIIRSLLDKNRQTLNETIFILDRPTGWFGVTAGMHRLMLDLNNWLFENHNLFLIGLEKSGAFVEHASQIQSKMENGSILILNDKYIYSYISPGHEDANRPYASTSYYGHKIIFKTKFGQMYVASLPVKDLKKNPDENDIPNLHEILSVIESLHCDMYENALLPIALTNKLVSLSAHPSTQILTNFAKATITK
>NZ_LS483485.1|WP_070613733.1|2010236_2012282_-|DUF87-domain-containing-protein
MLSISSSIANINLFERKFERENDPKSNWSWNTGIFVGRPFKISYTSSSILMADAWKEQANGVPQGCFLLAYYDCDPGKDNLQEALLLRVIEPAELPTDKDIVSSMVDYYKDHIRTGNTKQSQLDEYSRYEFGFSGLRCSILGSFYLDAKKNLRFGADVENFYAAHNYSVIKPSNEILGLIANYRENSVPGGNGDIRIGSIRYSSSQRFNNDIGDIPVYIQAKDFAGKRTALFGMTRTGKSNSIKKIIQANEQMSELAQYQLDKQNESPEEILKQFVGDAPKYPIGQIIFDINGEYANANLQDEGTAIFDIYQAKTDRYSIVEKDGFKVMKVNFYNEIEAGFELIKSYPLIADDTSKYMVNFKSVMLEKPYNYDSDRSAKTRYDRRLSVYKCILKAAGFKCSENEKVTFSVNKELLEEMDIPDVTSQSLKAGISLDLATEWWTALWDSYDSSVACNDYKQKKRKEWADDELKALLVILTRKSSSGGSIDRTGYLNLRPIVAQHTDKSQTPFEDDILQALRQGKIVIADLSSGDEELQRMYSERITRRIFRDSMNRFTNAQPNNFIQFYFEEAHNLFPKKDDKNLSQIYNRLAKEGAKLNLGLVYATQEVSSISSNILKATQNWFISHLNNEDEIKELRKYYDFSDFSDSLIRFSQNTDKGFVRVKTYSNSFVVPVQIDKFGK
>NZ_LS483485.1|WP_070613732.1|2012285_2013278_-|site-specific-DNA-methyltransferase
MKKNKFPRNISKVFERKSGALYLGDSLDLLQSKSFSNLNGKVNLIITSPPYPLNQKKSYGNKTGEEYLNWIKELTPLLAEKLADDGSLVVELGNSWEPGRPVQSLLALKALMSIAESAETNLRLIQEFVCYNPSRLPSPAQWVTVNPLRTVDSYTHVWWFSKTDYPKADNRKVLRPYSEAMKSLLKRGSYNAGKRPSEHSIGEKSFLNDRGGAISHNLFEIESIDENRKPRLPNAFSFSNSASNDFFHRECKRQNITVHPARMPIGLVKFFIQYLTDEGDLILDPFAGSNTTGFAAALLNRNWISIELQESYIEQAKIRFEDPILSYKEV

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_LS483485_2	2.3\|2001505\|34\|NZ_LS483485\|CRISPRCasFinder,CRT,PILER-CR	2001505-2001538	34	NZ_LS483485.1	2005263-2005296	0	1.0

1. spacer 2.3|2001505|34|NZ_LS483485|CRISPRCasFinder,CRT,PILER-CR matches to position: 2005263-2005296, mismatch: 0, identity: 1.0

acaacgagcaggcgtgggcggagaactatttgac	CRISPR spacer
acaacgagcaggcgtgggcggagaactatttgac	Protospacer
**********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LS483485_2	2.4\|2001571\|33\|NZ_LS483485\|CRISPRCasFinder,CRT,PILER-CR	2001571-2001603	33	NZ_KX753679	Pasteurella multocida strain RCAD0259 plasmid pRCADGH-2, complete sequence	4504-4536	0	1.0
NZ_LS483485_2	2.4\|2001571\|33\|NZ_LS483485\|CRISPRCasFinder,CRT,PILER-CR	2001571-2001603	33	GQ866235	Aggregatibacter actinomycetemcomitans strain D11S-1 plasmid S57, complete sequence	610-642	0	1.0
NZ_LS483485_2	2.5\|2001636\|34\|NZ_LS483485\|CRISPRCasFinder,CRT,PILER-CR	2001636-2001669	34	NZ_KX753679	Pasteurella multocida strain RCAD0259 plasmid pRCADGH-2, complete sequence	3746-3779	0	1.0
NZ_LS483485_2	2.5\|2001636\|34\|NZ_LS483485\|CRISPRCasFinder,CRT,PILER-CR	2001636-2001669	34	NC_021724	Aggregatibacter actinomycetemcomitans plasmid pS23A, complete sequence	2286-2319	0	1.0
NZ_LS483485_2	2.5\|2001636\|34\|NZ_LS483485\|CRISPRCasFinder,CRT,PILER-CR	2001636-2001669	34	NC_002579	Aggregatibacter actinomycetemcomitans plasmid pVT745, complete sequence	25226-25259	0	1.0
NZ_LS483485_2	2.5\|2001636\|34\|NZ_LS483485\|CRISPRCasFinder,CRT,PILER-CR	2001636-2001669	34	GQ866235	Aggregatibacter actinomycetemcomitans strain D11S-1 plasmid S57, complete sequence	1364-1397	0	1.0
NZ_LS483485_2	2.4\|2001571\|33\|NZ_LS483485\|CRISPRCasFinder,CRT,PILER-CR	2001571-2001603	33	NC_021724	Aggregatibacter actinomycetemcomitans plasmid pS23A, complete sequence	1531-1563	1	0.97
NZ_LS483485_2	2.4\|2001571\|33\|NZ_LS483485\|CRISPRCasFinder,CRT,PILER-CR	2001571-2001603	33	NC_002579	Aggregatibacter actinomycetemcomitans plasmid pVT745, complete sequence	24469-24501	2	0.939
NZ_LS483485_2	2.1\|2001371\|34\|NZ_LS483485\|CRISPRCasFinder,CRT	2001371-2001404	34	MT475811	Uncultured crAssphage clone CRB_ENV3 polymerase gene, partial cds	283-316	7	0.794
NZ_LS483485_2	2.3\|2001505\|34\|NZ_LS483485\|CRISPRCasFinder,CRT,PILER-CR	2001505-2001538	34	MH825706	Streptomyces phage Microdon, complete genome	6503-6536	10	0.706
NZ_LS483485_1	1.1\|1769952\|46\|NZ_LS483485\|CRISPRCasFinder	1769952-1769997	46	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	245215-245260	14	0.696

1. spacer 2.4|2001571|33|NZ_LS483485|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KX753679 (Pasteurella multocida strain RCAD0259 plasmid pRCADGH-2, complete sequence) position: , mismatch: 0, identity: 1.0

atttatggtgcgattacattaattgttgttcct	CRISPR spacer
atttatggtgcgattacattaattgttgttcct	Protospacer
*********************************

2. spacer 2.4|2001571|33|NZ_LS483485|CRISPRCasFinder,CRT,PILER-CR matches to GQ866235 (Aggregatibacter actinomycetemcomitans strain D11S-1 plasmid S57, complete sequence) position: , mismatch: 0, identity: 1.0

atttatggtgcgattacattaattgttgttcct	CRISPR spacer
atttatggtgcgattacattaattgttgttcct	Protospacer
*********************************

3. spacer 2.5|2001636|34|NZ_LS483485|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KX753679 (Pasteurella multocida strain RCAD0259 plasmid pRCADGH-2, complete sequence) position: , mismatch: 0, identity: 1.0

tttcaagttgttgtgcggttaataccgcactatt	CRISPR spacer
tttcaagttgttgtgcggttaataccgcactatt	Protospacer
**********************************

4. spacer 2.5|2001636|34|NZ_LS483485|CRISPRCasFinder,CRT,PILER-CR matches to NC_021724 (Aggregatibacter actinomycetemcomitans plasmid pS23A, complete sequence) position: , mismatch: 0, identity: 1.0

tttcaagttgttgtgcggttaataccgcactatt	CRISPR spacer
tttcaagttgttgtgcggttaataccgcactatt	Protospacer
**********************************

5. spacer 2.5|2001636|34|NZ_LS483485|CRISPRCasFinder,CRT,PILER-CR matches to NC_002579 (Aggregatibacter actinomycetemcomitans plasmid pVT745, complete sequence) position: , mismatch: 0, identity: 1.0

tttcaagttgttgtgcggttaataccgcactatt	CRISPR spacer
tttcaagttgttgtgcggttaataccgcactatt	Protospacer
**********************************

6. spacer 2.5|2001636|34|NZ_LS483485|CRISPRCasFinder,CRT,PILER-CR matches to GQ866235 (Aggregatibacter actinomycetemcomitans strain D11S-1 plasmid S57, complete sequence) position: , mismatch: 0, identity: 1.0

tttcaagttgttgtgcggttaataccgcactatt	CRISPR spacer
tttcaagttgttgtgcggttaataccgcactatt	Protospacer
**********************************

7. spacer 2.4|2001571|33|NZ_LS483485|CRISPRCasFinder,CRT,PILER-CR matches to NC_021724 (Aggregatibacter actinomycetemcomitans plasmid pS23A, complete sequence) position: , mismatch: 1, identity: 0.97

atttatggtgcgattacattaattgttgttcct	CRISPR spacer
atttatggtgcaattacattaattgttgttcct	Protospacer
***********.*********************

8. spacer 2.4|2001571|33|NZ_LS483485|CRISPRCasFinder,CRT,PILER-CR matches to NC_002579 (Aggregatibacter actinomycetemcomitans plasmid pVT745, complete sequence) position: , mismatch: 2, identity: 0.939

atttatggtgcgattacattaattgttgttcct	CRISPR spacer
atttatggtgcaattacattaattgttgttccc	Protospacer
***********.********************.

9. spacer 2.1|2001371|34|NZ_LS483485|CRISPRCasFinder,CRT matches to MT475811 (Uncultured crAssphage clone CRB_ENV3 polymerase gene, partial cds) position: , mismatch: 7, identity: 0.794

cgcctttttggtaggtttaaaaataaaaatgagt--	CRISPR spacer
aatcttattggtgggtttaaaaataaaa--gagttg	Protospacer
 ..*** *****.***************  ****

10. spacer 2.3|2001505|34|NZ_LS483485|CRISPRCasFinder,CRT,PILER-CR matches to MH825706 (Streptomyces phage Microdon, complete genome) position: , mismatch: 10, identity: 0.706

acaacgagcaggcgtgggcggagaactatttgac------	CRISPR spacer
ccaacgcgcaggcgtgggcgaagaa------ggcgcagca	Protospacer
 ***** *************.****      *.*

11. spacer 1.1|1769952|46|NZ_LS483485|CRISPRCasFinder matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 14, identity: 0.696

ttctcaacatcaagttatgcgggaatagctcagttggtagagcaca	CRISPR spacer
ctaaggggcacaatgtatgcgggaatagctcagttggtagagcgtc	Protospacer
.*   ..   ***  ****************************..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

96115 : 106155

Serratia_phage(16.67%)

integrase,tRNA

attL 96041:96057|attR 108738:108754

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
96041:96057	attL	NA	NA	NA	NA
WP_111300618.1\|96115_98131_+	NAD-dependent DNA ligase LigA	A0A289ZTZ3	Serratia_phage	1.3e-142	49.4
WP_005705008.1\|98316_98895_-	thymidine kinase	A0A076YPF1	Citrobacter_phage	5.2e-52	51.6
WP_109059177.1\|98897_99131_-	hypothetical protein	NA	NA	NA	NA
WP_111300616.1\|99202_100231_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	1.2e-110	58.3
WP_005701713.1\|100455_100671_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_111300614.1\|100793_102572_+	DNA primase	A0A1S5RF71	Helicobacter_phage	5.6e-44	31.6
WP_109842989.1\|102643_104515_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.0e-35	33.5
WP_032995430.1\|104913_106155_+\|integrase	integrase arm-type DNA-binding domain-containing protein	A0A1B5FPC6	Escherichia_phage	8.3e-71	38.0
108738:108754	attR	NA	NA	NA	NA

DBSCAN-SWA_2

504245 : 552905

uncultured_Mediterranean_phage(28.57%)

protease,tRNA,integrase,plate

attL 495051:495065|attR 554244:554258

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
495051:495065	attL	NA	NA	NA	NA
WP_111301496.1\|504245_505343_-\|tRNA	tRNA (uridine(54)-C5)-methyltransferase TrmA	NA	NA	NA	NA
WP_005701977.1\|505402_505732_-	DUF413 domain-containing protein	NA	NA	NA	NA
WP_111301498.1\|505790_506408_-	DsbA family protein	NA	NA	NA	NA
WP_005703612.1\|506422_506689_-	YihD family protein	NA	NA	NA	NA
WP_005703611.1\|506755_507337_+	molybdenum cofactor guanylyltransferase MobA	NA	NA	NA	NA
WP_083014296.1\|507447_507969_+	hypothetical protein	NA	NA	NA	NA
WP_111301502.1\|509619_510561_+	1-phosphofructokinase	NA	NA	NA	NA
WP_111301504.1\|510565_512230_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_005703604.1\|512366_512603_+	hypothetical protein	NA	NA	NA	NA
WP_111711189.1\|512804_513788_+	DUF4424 family protein	NA	NA	NA	NA
WP_005703599.1\|513811_514231_+	DUF4189 domain-containing protein	NA	NA	NA	NA
WP_111711190.1\|517048_517693_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.3e-43	46.0
WP_111301209.1\|517799_521030_-\|protease	autotransporter serine protease	NA	NA	NA	NA
WP_005703593.1\|521519_525203_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_005701995.1\|525199_526627_-	type VI secretion system domain-containing protein	NA	NA	NA	NA
WP_005701996.1\|526628_527255_-	type VI secretion protein	NA	NA	NA	NA
WP_005703591.1\|527280_528138_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_005701999.1\|528134_529478_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_005703590.1\|529481_530168_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_005702001.1\|530182_530968_-	hypothetical protein	NA	NA	NA	NA
WP_111301203.1\|530969_531968_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_005703587.1\|531931_533683_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_005702007.1\|533683_534100_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_005703586.1\|534109_535594_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_005702010.1\|535615_536113_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_111301202.1\|536304_536964_-\|tRNA	bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA	NA	NA	NA	NA
WP_111711191.1\|536966_539828_-	RNA polymerase-associated protein RapA	A0A1B1IUI1	uncultured_Mediterranean_phage	5.0e-18	37.0
WP_005702013.1\|540025_540715_+	nicotinamide riboside transporter PnuC	U5J9C5	Bacillus_phage	1.8e-35	34.4
WP_111301199.1\|540771_541476_-\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
WP_111301197.1\|541565_542894_+	ATP-dependent RNA helicase SrmB	A0A1B1IS59	uncultured_Mediterranean_phage	6.9e-47	31.1
WP_111301195.1\|542915_545516_+	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	2.3e-30	21.7
WP_111711192.1\|545794_547138_-	AAA family ATPase	NA	NA	NA	NA
WP_111301191.1\|547124_547970_-	AAA family ATPase	NA	NA	NA	NA
WP_032995056.1\|548160_549285_-	Fic family protein	D7RWK9	Brochothrix_phage	2.1e-25	28.0
WP_111301187.1\|549707_550799_-	YdcF family protein	NA	NA	NA	NA
WP_111711193.1\|551660_552905_+\|integrase	tyrosine-type recombinase/integrase	A0A1B5FPC6	Escherichia_phage	8.6e-84	40.3
554244:554258	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1441035 : 1522899

uncultured_Caudovirales_phage(30.43%)

protease,capsid,terminase,portal,integrase,tRNA,head,tail,transposase

attL 1472211:1472232|attR 1504542:1504563

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111300071.1\|1441035_1441257_-\|transposase	transposase	Q716C2	Shigella_phage	2.4e-13	50.7
WP_109842834.1\|1441435_1442878_-	serine-type D-Ala-D-Ala carboxypeptidase	NA	NA	NA	NA
WP_109842833.1\|1443030_1443507_+	transcription elongation factor GreA	NA	NA	NA	NA
WP_050693758.1\|1443571_1443874_-	ribosome assembly RNA-binding protein YhbY	NA	NA	NA	NA
WP_005703292.1\|1443974_1444589_-	riboflavin synthase	NA	NA	NA	NA
WP_111300460.1\|1444613_1446011_+	MATE family efflux transporter	NA	NA	NA	NA
WP_111300069.1\|1446171_1448343_+	TonB-dependent receptor	NA	NA	NA	NA
WP_111711256.1\|1448398_1450144_+	ABC transporter ATP-binding protein/permease	G9BWD6	Planktothrix_phage	3.1e-07	26.5
WP_111300458.1\|1450254_1450575_-	YciU family protein	NA	NA	NA	NA
WP_111300065.1\|1450678_1453318_-	phosphoenolpyruvate carboxylase	NA	NA	NA	NA
WP_032994854.1\|1453602_1454601_-	HTH-type transcriptional repressor PurR	C6ZCU4	Enterobacteria_phage	4.2e-33	31.2
WP_032994904.1\|1454927_1456031_-	homoserine O-acetyltransferase	NA	NA	NA	NA
WP_065295092.1\|1456211_1456925_+	YdcF family protein	NA	NA	NA	NA
WP_005703282.1\|1456902_1457895_-	catabolite repressor/activator	NA	NA	NA	NA
WP_005700607.1\|1458375_1458987_+	hypothetical protein	NA	NA	NA	NA
WP_005703276.1\|1460837_1461098_-	acetolactate synthase	NA	NA	NA	NA
WP_005703275.1\|1461241_1461502_-	acetolactate synthase 3 catalytic subunit	NA	NA	NA	NA
WP_172452391.1\|1461529_1462192_-	acetolactate synthase	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	4.5e-23	33.5
WP_032994852.1\|1462624_1464154_-	Na+/H+ antiporter NhaC family protein	NA	NA	NA	NA
WP_005703272.1\|1464593_1464992_+	H-NS histone family protein	NA	NA	NA	NA
WP_005700590.1\|1465062_1465899_+	formyltetrahydrofolate deformylase	NA	NA	NA	NA
WP_005700586.1\|1466062_1466692_+	23S rRNA (uridine(2552)-2'-O)-methyltransferase RlmE	NA	NA	NA	NA
WP_111300063.1\|1466805_1468746_+\|protease	ATP-dependent zinc metalloprotease FtsH	M4QMW8	Micromonas_pusilla_virus	1.7e-115	41.8
WP_111300061.1\|1468834_1469365_+	elongation factor P hydroxylase	NA	NA	NA	NA
WP_111711257.1\|1469441_1470281_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	A0A2I7SAX1	Vibrio_phage	9.0e-37	37.0
WP_083015382.1\|1470289_1471072_-	Zn-ribbon-containing protein	NA	NA	NA	NA
WP_005700578.1\|1471179_1471497_+	YqcC family protein	NA	NA	NA	NA
WP_111300057.1\|1471490_1472201_+\|tRNA	tRNA pseudouridine(65) synthase TruC	NA	NA	NA	NA
1472211:1472232	attL	NA	NA	NA	NA
WP_033002552.1\|1472254_1472416_+	YoaH family protein	NA	NA	NA	NA
WP_005700573.1\|1472625_1472835_+	cold shock domain-containing protein CspD	A0A1J0GVA5	Vibrio_phage	2.1e-11	53.1
WP_050693738.1\|1472900_1473347_-	macrodomain Ter protein MatP	NA	NA	NA	NA
WP_111300055.1\|1473482_1475258_+\|protease	Lon protease family protein	NA	NA	NA	NA
WP_111300053.1\|1475399_1475930_+	bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase	NA	NA	NA	NA
WP_111300051.1\|1476384_1477581_+\|integrase	integrase arm-type DNA-binding domain-containing protein	A0A1V0E8G8	Vibrio_phage	2.2e-76	38.0
WP_111300049.1\|1477745_1479536_-	DNA primase	Q7M2A8	Enterobacteria_phage	4.3e-76	38.1
WP_111300047.1\|1479519_1479963_-	hypothetical protein	NA	NA	NA	NA
WP_109082734.1\|1479962_1480277_-	hypothetical protein	NA	NA	NA	NA
WP_111300045.1\|1480276_1480486_-	hypothetical protein	NA	NA	NA	NA
WP_111300043.1\|1480482_1480686_-	hypothetical protein	NA	NA	NA	NA
WP_111300041.1\|1480678_1480909_-	hypothetical protein	NA	NA	NA	NA
WP_111300039.1\|1480901_1481117_-	host cell division inhibitor Icd-like protein	NA	NA	NA	NA
WP_111711258.1\|1481311_1481488_+	DUF3950 domain-containing protein	A0A0K2FIR8	Escherichia_phage	3.2e-05	38.6
WP_111300035.1\|1481742_1482054_-	hypothetical protein	NA	NA	NA	NA
WP_111300033.1\|1482065_1482269_-	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_111300031.1\|1482455_1483427_-	hypothetical protein	NA	NA	NA	NA
WP_172452405.1\|1483521_1483854_-	hypothetical protein	NA	NA	NA	NA
WP_111300027.1\|1483977_1484262_-	hypothetical protein	NA	NA	NA	NA
WP_111300025.1\|1484258_1485926_-\|terminase	terminase large subunit	A0A2H4JB64	uncultured_Caudovirales_phage	3.4e-245	71.6
WP_111300023.1\|1485932_1486301_-\|terminase	phage terminase small subunit P27 family	A0A2H4JHS3	uncultured_Caudovirales_phage	1.7e-35	64.3
WP_111300021.1\|1486403_1486766_-	HNH endonuclease	A0A2H4JAS8	uncultured_Caudovirales_phage	1.1e-28	53.6
WP_006719251.1\|1486780_1487095_-\|head,tail	phage gp6-like head-tail connector protein	A0A2H4JD08	uncultured_Caudovirales_phage	2.7e-18	49.5
WP_041175043.1\|1487081_1487426_-\|head	phage head closure protein	NA	NA	NA	NA
WP_111300019.1\|1487409_1488642_-\|portal	phage portal protein	A0A2H4JFJ9	uncultured_Caudovirales_phage	4.7e-143	62.3
WP_111300017.1\|1488643_1489210_-\|head,protease	HK97 family phage prohead protease	A0A2H4JB68	uncultured_Caudovirales_phage	9.7e-51	64.6
WP_111300015.1\|1489263_1490451_-\|capsid	phage major capsid protein	A0A2H4JED2	uncultured_Caudovirales_phage	6.8e-131	63.0
WP_005703257.1\|1491091_1492402_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	2.9e-66	36.3
WP_111300011.1\|1492407_1492764_+	DsrE family protein	NA	NA	NA	NA
WP_111300009.1\|1492826_1496489_+	exodeoxyribonuclease V subunit beta	NA	NA	NA	NA
WP_111300007.1\|1496488_1498468_+	exodeoxyribonuclease V subunit alpha	A0A1P8DII4	Virus_Rctr197k	6.3e-04	50.0
WP_005551622.1\|1498480_1499077_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_005700564.1\|1499318_1499747_+	50S ribosomal protein L13	NA	NA	NA	NA
WP_005700563.1\|1499764_1500157_+	30S ribosomal protein S9	NA	NA	NA	NA
WP_111300005.1\|1500308_1501094_+\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_111300003.1\|1501272_1502691_+	PTS trehalose transporter subunit IIBC	NA	NA	NA	NA
WP_111300001.1\|1502824_1504447_+	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
WP_111299999.1\|1504634_1505417_+	MmcQ/YjbR family DNA-binding protein	NA	NA	NA	NA
1504542:1504563	attR	NA	NA	NA	NA
WP_111299997.1\|1505484_1507965_-	trimethylamine-N-oxide reductase TorA	NA	NA	NA	NA
WP_111711259.1\|1508028_1509126_-	NapC/NirT family cytochrome c	NA	NA	NA	NA
WP_111299993.1\|1509430_1510879_+\|tRNA	tRNA 4-thiouridine(8) synthase ThiI	NA	NA	NA	NA
WP_012771509.1\|1511137_1511287_+	nitrate/trimethylamine N-oxide reductase NapE/TorE	NA	NA	NA	NA
WP_005703242.1\|1511302_1512478_+	pentaheme c-type cytochrome TorC	NA	NA	NA	NA
WP_111299991.1\|1512489_1514949_+	trimethylamine-N-oxide reductase TorA	A0A077SK27	Escherichia_phage	5.3e-61	26.3
WP_050332701.1\|1514899_1515523_+	molecular chaperone TorD	NA	NA	NA	NA
WP_111299989.1\|1515602_1516307_-	dipeptidase PepE	NA	NA	NA	NA
WP_005703237.1\|1516444_1517419_-	uridine diphosphate-N-acetylglucosamine-binding protein YvcK	A1IMD5	Streptococcus_phage	1.2e-32	30.3
WP_111300456.1\|1517778_1518792_+	GTP 3',8-cyclase MoaA	NA	NA	NA	NA
WP_111711260.1\|1518846_1519335_+	cyclic pyranopterin monophosphate synthase MoaC	NA	NA	NA	NA
WP_111299985.1\|1519328_1519574_+	molybdopterin synthase sulfur carrier subunit	NA	NA	NA	NA
WP_111299983.1\|1519574_1520030_+	molybdopterin synthase catalytic subunit MoaE	NA	NA	NA	NA
WP_005703231.1\|1520233_1520875_+	stringent starvation protein A	NA	NA	NA	NA
WP_005703230.1\|1520886_1521330_+\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	2.0e-27	57.8
WP_109064004.1\|1521495_1522899_-\|tRNA	asparagine--tRNA ligase	A0A1V0SDB6	Indivirus	5.3e-82	37.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LS483485

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection