CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LR595857	Streptococcus sp. NCTC 11567 strain NCTC11567 chromosome 1	3 crisprs	DEDDh,cas9,cas1,csn2,csm6,DinG,cas2,cas4,cas7,cas8c,cas5,cas3,WYL,PD-DExK,RT,csa3	0	9	8	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LR595857_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LR595857_1

217863-218009

Orphan

Consensus_repeat	Method
CTTGCTGAAGTTCAAACTCATATCCGTGAGAAATTAAAAGCAGAGAAAGCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LR595857_1

>merge|NZ_LR595857|1|217863-218009|CRISPRCasFinder
CTTGCTGAAGTTCAAACTCATATCCGTGAGAAATTAAAAGCAGAGAAAGCTCAAGTTGAAGAGAAGCTAAAGGAAGCTCGACTTAACTATCAAGACCTTGCTGAAGTTCAAACTCATATCCGTGAGAAATTAGAAGCAGAGAAAGCT

>NZ_LR595857|1|1|217863-218009|CRISPRCasFinder
CTTGCTGAAGTTCAAACTCATATCCGTGAGAAATTAAAAGCAGAGAAAGCT	CAAGTTGAAGAGAAGCTAAAGGAAGCTCGACTTAACTATCAAGAC
CTTGCTGAAGTTCAAACTCATATCCGTGAGAAATTAGAAGCAGAGAAAGCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LR595857.1\|WP_046177210.1\|223953_224397_+\|D-tyrosyl-tRNA(Tyr)-deacylase	unknown	unknown	gnl\|CDD\|235383
NZ_LR595857.1\|WP_046177213.1\|213439_214420_-\|nucleoside-hydrolase	unknown	unknown	gnl\|CDD\|239119
NZ_LR595857.1\|WP_046177216.1\|210407_211232_+\|endonuclease/exonuclease/phosphatase-family-protein	unknown	unknown	gnl\|CDD\|197313
NZ_LR595857.1\|WP_003061170.1\|205941_206700_+\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	unknown	unknown	gnl\|CDD\|224303
NZ_LR595857.1\|WP_022554186.1\|228506_230120_+\|alpha-glucosidase	unknown	unknown	gnl\|CDD\|200472
NZ_LR595857.1\|WP_015016595.1\|211240_211753_-\|kinase	unknown	unknown	gnl\|CDD\|235858
NZ_LR595857.1\|WP_046177225.1\|219085_221464_-\|bifunctional-2',3'-cyclic-nucleotide-2'-phosphodiesterase/3'-nucleotidase	unknown	unknown	gnl\|CDD\|237019
NZ_LR595857.1\|WP_014611970.1\|214700_215168_-\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	unknown	unknown	gnl\|CDD\|179443
NZ_LR595857.1\|WP_046177224.1\|226145_226994_+\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225306
NZ_LR595857.1\|WP_046177217.1\|206865_207873_+\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380517
NZ_LR595857.1\|WP_046177209.1\|224494_225817_-\|streptokinase	unknown	unknown	gnl\|CDD\|367201
NZ_LR595857.1\|WP_046177211.1\|221719_223939_+\|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|223394
NZ_LR595857.1\|WP_003062175.1\|215655_217197_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|285470
NZ_LR595857.1\|WP_003057915.1\|227291_228425_+\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	unknown	unknown	gnl\|CDD\|236947
NZ_LR595857.1\|WP_046177214.1\|212884_213436_-\|ECF-transporter-S-component	unknown	unknown	unknown
NZ_LR595857.1\|WP_014611967.1\|208142_210329_+\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|131058
NZ_LR595857.1\|WP_003057937.1\|234507_234858_+\|conjugal-transfer-protein-TraF	unknown	unknown	gnl\|CDD\|239245
NZ_LR595857.1\|WP_046177208.1\|230285_233909_+\|pullulanase	unknown	unknown	gnl\|CDD\|273973
NZ_LR595857.1\|WP_012766514.1\|234061_234352_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LR595857.1\|WP_046177215.1\|211776_212814_-\|M42-family-metallopeptidase	unknown	unknown	gnl\|CDD\|349907

Protein	Function_ID	Function_description	E-value
NZ_LR595857.1\|WP_046177210.1\|223953_224397_+\|D-tyrosyl-tRNA(Tyr)-deacylase	gnl\|CDD\|235383	PRK05273, PRK05273, D-tyrosyl-tRNA(Tyr) deacylase; Provisional.	6.84547e-93
NZ_LR595857.1\|WP_046177213.1\|213439_214420_-\|nucleoside-hydrolase	gnl\|CDD\|239119	cd02653, nuc_hydro_3, NH_3: A subgroup of nucleoside hydrolases. This group contains eukaryotic and bacterial proteins similar to nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity. .	1.03584e-138
NZ_LR595857.1\|WP_046177216.1\|210407_211232_+\|endonuclease/exonuclease/phosphatase-family-protein	gnl\|CDD\|197313	cd09079, RgfB-like, Streptococcus agalactiae RgfB, part of a putative two component signal transduction system, and related proteins. This family includes Streptococcus agalactiae RgfB (for regulator of fibrinogen binding) and related proteins. The function of RgfB is unknown. It is part of a putative two component signal transduction system designated rgfBDAC (the rgf locus was identified in a screen for mutants of Streptococcus agalactiae with altered binding to fibrinogen). RgfA,-C,and -D do not belong to this superfamily: rgfA encodes a putative response regulator, and rgfC, a putative histidine kinase. All four genes are co-transcribed, and may be involved in regulating expression of bacterial cell surface components. This family belongs to the large EEP (exonuclease/endonuclease/phosphatase) superfamily that contains functionally diverse enzymes that share a common catalytic mechanism of cleaving phosphodiester bonds.	6.86441e-101
NZ_LR595857.1\|WP_003061170.1\|205941_206700_+\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	gnl\|CDD\|224303	COG1385, COG1385, Uncharacterized protein conserved in bacteria [Function unknown].	3.32966e-85
NZ_LR595857.1\|WP_022554186.1\|228506_230120_+\|alpha-glucosidase	gnl\|CDD\|200472	cd11333, AmyAc_SI_OligoGlu_DGase, Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins. The sucrose isomerases (SIs) Isomaltulose synthase (EC 5.4.99.11) and Trehalose synthase (EC 5.4.99.16) catalyze the isomerization of sucrose and maltose to produce isomaltulose and trehalulose, respectively. Oligo-1,6-glucosidase (EC 3.2.1.10) hydrolyzes the alpha-1,6-glucosidic linkage of isomaltooligosaccharides, pannose, and dextran. Unlike alpha-1,4-glucosidases (EC 3.2.1.20), it fails to hydrolyze the alpha-1,4-glucosidic bonds of maltosaccharides. Dextran glucosidase (DGase, EC 3.2.1.70) hydrolyzes alpha-1,6-glucosidic linkages at the non-reducing end of panose, isomaltooligosaccharides and dextran to produce alpha-glucose.The common reaction chemistry of the alpha-amylase family enzymes is based on a two-step acid catalytic mechanism that requires two critical carboxylates: one acting as a general acid/base (Glu) and the other as a nucleophile (Asp). Both hydrolysis and transglycosylation proceed via the nucleophilic substitution reaction between the anomeric carbon, C1 and a nucleophile. Both enzymes contain the three catalytic residues (Asp, Glu and Asp) common to the alpha-amylase family as well as two histidine residues which are predicted to be critical to binding the glucose residue adjacent to the scissile bond in the substrates. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
NZ_LR595857.1\|WP_015016595.1\|211240_211753_-\|kinase	gnl\|CDD\|235858	PRK06762, PRK06762, hypothetical protein; Provisional.	2.56412e-89
NZ_LR595857.1\|WP_046177225.1\|219085_221464_-\|bifunctional-2',3'-cyclic-nucleotide-2'-phosphodiesterase/3'-nucleotidase	gnl\|CDD\|237019	PRK11907, PRK11907, bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase.	0
NZ_LR595857.1\|WP_014611970.1\|214700_215168_-\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	gnl\|CDD\|179443	PRK02551, PRK02551, flavoprotein NrdI; Provisional.	4.27648e-98
NZ_LR595857.1\|WP_046177224.1\|226145_226994_+\|PucR-family-transcriptional-regulator	gnl\|CDD\|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	2.58445e-49
NZ_LR595857.1\|WP_046177217.1\|206865_207873_+\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|380517	cd06294, PBP1_MalR-like, ligand-binding domain of maltose transcription regulator MalR which is a member of the LacI-GalR family repressors. This group includes the ligand-binding domain of maltose transcription regulator MalR which is a member of the LacI-GalR family repressors that are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	1.0031e-93
NZ_LR595857.1\|WP_046177209.1\|224494_225817_-\|streptokinase	gnl\|CDD\|367201	pfam02821, Staphylokinase, Staphylokinase/Streptokinase family.	5.3379e-28
NZ_LR595857.1\|WP_046177211.1\|221719_223939_+\|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	gnl\|CDD\|223394	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription].	0
NZ_LR595857.1\|WP_003062175.1\|215655_217197_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|285470	pfam08270, PRD_Mga, M protein trans-acting positive regulator (MGA) PRD domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This corresponds to the PRD like region.	5.97658e-32
NZ_LR595857.1\|WP_003057915.1\|227291_228425_+\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	gnl\|CDD\|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	0
NZ_LR595857.1\|WP_014611967.1\|208142_210329_+\|PTS-transporter-subunit-EIIC	gnl\|CDD\|131058	TIGR02003, PTS_system_glucose-specific_IIBC_component, PTS system, IIBC component. This model represents a family of fused B and C components of PTS enzyme II. This clade is a member of a larger family which contains enzyme II's specific for a variety of sugars including glucose (TIGR02002) and N-acetylglucosamine (TIGR01998). None of the members of this clade have been experimentally characterized. This clade includes sequences from Streptococcus and Enterococcus which also include a C-terminal A domain as well as Bacillus and Clostridium which do not. In nearly all cases, these species also contain an authentic glucose-specific PTS transporter. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
NZ_LR595857.1\|WP_003057937.1\|234507_234858_+\|conjugal-transfer-protein-TraF	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.44907e-14
NZ_LR595857.1\|WP_046177208.1\|230285_233909_+\|pullulanase	gnl\|CDD\|273973	TIGR02102, alkaline_amylopullulanase, pullulanase, extracellular, Gram-positive. Pullulan is an unusual, industrially important polysaccharide in which short alpha-1,4 chains (maltotriose) are connected in alpha-1,6 linkages. Enzymes that cleave alpha-1,6 linkages in pullulan and release maltotriose are called pullulanases although pullulan itself may not be the natural substrate. In contrast, a glycogen debranching enzyme such GlgX, homologous to this family, can release glucose at alpha,1-6 linkages from glycogen first subjected to limit degradation by phosphorylase. Characterized members of this family include a surface-located pullulanase from Streptococcus pneumoniae () and an extracellular bifunctional amylase/pullulanase with C-terminal pullulanase activity (.	0
NZ_LR595857.1\|WP_046177215.1\|211776_212814_-\|M42-family-metallopeptidase	gnl\|CDD\|349907	cd05657, M42_glucanase_like, M42 Peptidase, endoglucanase-like subfamily. Peptidase M42 family, glucanase (endo-1,4-beta-glucanase or endoglucanase)-like subfamily. Proteins in this subfamily are co-catalytic metallopeptidases, found in archaea and bacteria. They show similarity to cellulase and endo-1,4-beta-glucanase (endoglucanase) which typically bind two zinc or cobalt atoms. Some of the enzymes exhibit typical aminopeptidase specificity, whereas others are also capable of N-terminal deblocking activity, i.e. hydrolyzing acylated N-terminal residues. Many of these enzymes are assembled either as tetrahedral dodecamers or as octahedral tetracosameric structures, with the active site located on the inside such that substrate sizes are limited, indicating function as possible peptide scavengers.	2.63151e-179

>NZ_LR595857.1|WP_003062175.1|215655_217197_+|helix-turn-helix-domain-containing-protein
MTHASKLFTKQQWRELELIAHLTEHSGRMGYKDRELCKVLDSTVSTLQACIANLQFMESLGRITYEDGYLTIDYNDHCGLQEVYQRALRESQSLQLLSALFFKEFDSLEDLADALFISLSTLKRLITRTNGYLKKEFGIKISTRPVMVVGDEHHIRLFYLKYFSEAYTISEWPFAEIINQNNLERLIALMVKQTDVSVNFALFQHLKILSGVNLIRFQKGFTLNRKDKGLEHLFMKVLEDSLEMKDLSALFALKYNQPLDARALAEIFSNYLNPALELGKLLQSDDSAREQTLSSHQIVPWIALLDKIEKSLQLSISNKYELARHLQTTVILAEEDISANFLIYDYKKEYLKFFHKHYRVIYDTFLTYVEDLFALDHQEFNEGIRNHLLYCLFITWENLFLKISQSRRKLKLLVIERSYSNVGNFLKEYFGEFFEIISFDDLGNPKIDLLPLAKEYDVIVTDVILEQNNHSEILFFNQMIPSVVADKLTDFLKVKVGEDKLFESVALNQMSTS
>NZ_LR595857.1|WP_014611970.1|214700_215168_-|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI
MSDLTIVFISLSGNTLSFVKRLSLYLTENHECHVKQINIKDLKHETFPVEEDFVAMLPTYLEGGNGIDSGEVEILTNPLGDFIAAHDNYKHCMGIIGSGNKNFNNQYCLTAKQYAKRFGFPMLGDFELRGTNDDIERLAKIILERRDAFRASSEG
>NZ_LR595857.1|WP_046177213.1|213439_214420_-|nucleoside-hydrolase
MTKQPIIIDCDPGIDDSLALLYALKHPKLEVIAITLVQGNVPVPIGLQNTILLLERVNRLDIPIYLGRGIPLERDYVSAQDTHGIDGLGDSLLQPSVIKEAEALPAADFLAQHFAEPSETAIIALGPLTNVAEALGQNPNMGKHCQRFVSMGGAFKAHGNCSPVAEYNYWCDPHAARLTFQQLGRKLEMVGLDVTRQIVLTPNHLSYMARLNPEETAFIESITHFYFDFHWEYEHLIGCVINDPLAVVYFLAPTICQGFDSYTDVATEGITLGQTVVDQYDFYHKKANSHILTTVNSKAFWSEFIATILEVPLHQVVRDLDHLQLG
>NZ_LR595857.1|WP_046177214.1|212884_213436_-|ECF-transporter-S-component
MTKIKTQVLTFIAAAIALNYLGANIALFLKLPLYLDMIGTLLIALLFGPWLGAVTAIVSALLSWMTTDIFALFYAPVAIITALTAGVFLRQHNRAKDLIWKALCISFPGTLVASIITVILFKGITSSGSSLLVQILHGLGLDLTVSVIVIQAGTDYLDRLVSLLLVLMISKALRKQLPHLFQI
>NZ_LR595857.1|WP_046177215.1|211776_212814_-|M42-family-metallopeptidase
MKTTVEYLTKLANIPSPTGFTRKIMDYVHDELSQFGYEPVRTHKGGIMVSIKGKNDDKHRVVTAHLDTLGAMVRAIKPDGRLKMDLVGGFVYNSIEGENCTVHLAKSGKEISGTILLHQTSVHVYKDAGSAERNQANMEVRLDEKVTTADETRALGIEVGDFISFDPRVIVTESGFIKSRHLDDKVSAAILMELLKCYKEEQVELPYTTHFYFSAFEEVGHGANSSLPAQVVEYLAVDMGAMGDDQATDEYTVSICVKDGSGPYHYELRQHLVALCQDHQIPYQLDIYPYYGSDASAAMRAGAEVRHALLGAGIESSHSYERTHTDSIEATERLVDAYLKSTMID
>NZ_LR595857.1|WP_015016595.1|211240_211753_-|kinase
MTKLILIRGNAASGKTSLANALQSQLGENTLLLSQDKLRREMLLAHDGFDTPTIPLLKHLITFGMANCDYIILEGILKADWYAPVWDFISQQSRLQVFAYYYDIPFEETLKRHSSRSKVEEFGEEALRKWWNEKDYIKIISETSFDKTVTLQEALNYILQDITKRSGLTS
>NZ_LR595857.1|WP_046177216.1|210407_211232_+|endonuclease/exonuclease/phosphatase-family-protein
MTKLLTLNTHSWMEANALKKLVDLAEHILAEKYDIICLQEINQLIESELAMELPSYQPIPGTPTIHKDHFALLLIHYLKKRGQHYYWSWAYNHIGYDIYHEGVAILSKQPIHVSDILVSAMDDETDYHTRRSLVAKTKLDGKEVAVVNVHLSWFDKGFLGEWEKLEKELLTLKCPLLLMGDFNNPTNQEGYQVIMGSPLNLQDSHKVADHVFGDHSIVADIDGWEDNKEAFKVDHVFTSKDFDIKASHITFEGGDAPVVSDHYGLEVTLDWVEK
>NZ_LR595857.1|WP_014611967.1|208142_210329_+|PTS-transporter-subunit-EIIC
MKTSFKQLFSFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMINHNSAFLASLGNIIAQIGWAIIVNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRITGAFYGVSGAMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGATAYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSILVALVLVVVWPVIQSGINGFGMWIASSQDSAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQDPLWLAWVTDLVHLKGSDASAYHQLMDGVTPARFKVGQMIGATGTLMGVALAMYRNVDADKKHKYKMMFISAAAAVFLTGVTEPLEYMFMFAAMPLYLVYALVQGASFAMADLVNLRVHSFGNIELLTRTPMALKAGLGMDLINFVWVSILFAVIMYFIADMMIKKMHLATAGRLGNYEADMLDDNKAKSSGAPMADSNSQVVQIVNLLGGRDNIDDVDACMTRLRVTVKDPAKVGAEDDWKKAGAMGLITKGSGVQAVYGPKADILKSDIQDLLDSGAIIPEVNMSKVADKPMPAKDFRHVTEEVLSVADGTVLQITGVKDQVFAAKMMGDGFAVEPTNGNIYAPVSGLVTSVFPTKHAFGLLTDSGLEVLVHVGLDTVALNGVPFSVKVTEGQRIEAGDLLVVADLAAIQSAERETTIVVAFTNTAEIQDVTLTSLGAQPAKTPVATVEL
>NZ_LR595857.1|WP_046177217.1|206865_207873_+|LacI-family-DNA-binding-transcriptional-regulator
MVTIKDVAKLAGVSASTASRAINDNHMISQATKERVRKAMETLDYSPNYSAQNLVKRQSNAVGIILPVRVIQDSLGNNPFFMQIIQGIAGVCTDNGYMVSLATGRSDDELLKNVQNMIRSGHIGKLIFLYSKTDDKVFDFVKKQAVDCVVVGQSYATDNGNAKFVDNDNRQAGYDAAAFLLERGFKQITYAYTDMDELVQAERFIGYAEKMTSQGLTAQTINLSSETEQDIGQRIQKFLTNHPQPAFVTCDDMLAIHLQRLLKQNHPNPKVPMISFNNSILAELATPSLTSVEIFPYQLGEKAATLVLATDHIQDTIHLISHQIVERESTQPITP
>NZ_LR595857.1|WP_003061170.1|205941_206700_+|16S-rRNA-(uracil(1498)-N(3))-methyltransferase
MQQYFIKGKAEKEVTITDKDTIKHMFQVMRLTDEAEVVLVFDDGIKYLAKVTNSMAHELEIIEALPDQVELPVKVTIASGFPKGDKLDTIAQKVTELGASALWGYPADWSVVKWDGKKLAKKEDKLAKIVLGAAEQSKRNVVPEVHLFEQKAEFLKSLSSFDHIFIAYEETAKAGQLATLARELKEVKPGAKLLFIFGPEGGISPAEITQFEAAGAIKVGLGPRIMRTETAPLYALSAISYALELQVTSDDN
>NZ_LR595857.1|WP_046177225.1|219085_221464_-|bifunctional-2',3'-cyclic-nucleotide-2'-phosphodiesterase/3'-nucleotidase
MTKGYMSKSAIFLAMLVAAGSAQLTKAEETTAVEPLTTTANTTTSTAVPAETAPLVADTTPATATADTAVPSPVNSTSSEMATASADNATVTAPVEGQSVDVRILSTTDLHSNLVNYDYYQDKEAQSLGLAKTAVLIDAAKKENSNVVLVDNGDILQGTPLATYKAIVDPVEADEVHPMYAALKALNFDASTLGNHEFNYGLDYLDRVMATAGLPIVNANVLDAKTGKPKFKPFDIITKTFTDKDGKTVSLKIGITGVVPPQIMSWDKANLTGKVTVKDAVEAVKEVIPTIRAAGADLVLVLAHTGIGDDVYEVGEENVGYQIASLEGVDAVVTGHSHADFPALPDGSFYDNLKGVDGKKGLINGVPVTMGGKYGDHLGLIDLNLTYTNGQWKVNKDQSRAETRQIDSKSNQVDPTIVALAKEAHDGTVAYVRQQVGTTTAPINSYFALIKDDPSIQIVNNAQRWYAEKELAGTPEANLPLLSAAAPFKAGTRNDASAYTDIPAGPIAIKNVADLYLYDNVTAILKVTGADLKEWLEMSAGQFNTIDPSKSEPQDLVNTSYRTYNFDVIDGLTYEFDVTQKNKYDSKGNLVNPDASRVRNLKYMGKDIDPKQEFMVVTNNYRASGNFPGVKNATLNRLLNLENRQAIINYIVSEKTINPSADNNWYFADTIKGLNLRFLSADKAKGLIGNYKDISYVGPSSVEGFGDYSFTYVAPRQAETTTPALPGKTLTEQDRQAIHQLAARVYQETHQAASGKDSQLPTTGSADSKGLVFFGISLMGLVAVFSRKQERN
>NZ_LR595857.1|WP_046177211.1|221719_223939_+|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase
MAKEINLTGEEVVALAAKYMNETDAAFVKKALDYATAAHFYQVRKSGEPYIVHPIQVAGILADLHLDAVTVACGFLHDVVEDTDITLDNIEFDFGKDVRDIVDGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNETEFYKISHMMNEKRREREALVDDIVTKIKSYTTEQGLFGDVYGRPKHIYSIYRKMRDKKKRFDQIFDLIAIRCVMETQSDVYAMVGYIHELWRPMPGRFKDYIAAPKANGYQSIHTTVYGPKGPIEIQIRTKEMHQVAEYGVAAHWAYKKGVRGKVNQAEQKVGMNWIKELVELQDASNGDAVDFVDSVKEDIFSERIYVFTPTGAVQELPKDSGPIDFAYAIHTQVGEKATGAKVNGRMVPLTAKLKTGDVVEIVTNPNSFGPSRDWIKLVKTNKARNKIRQFFKNQDKELSVNKGRDMLVSYFQEQGYVANKYLDKKRIEAILPKVSVKSEESLYAAVGFGDISPVSVFNKLTEKERREEERAKAKAEAEELVNGGEIKHENKDVLKVRSENGVIIQGASGLLMRIAKCCNPVPGDPIEGYITKGRGIAIHRADCNNIKSQDGYQERLIEVEWDLDNSSKDYQAEIDIYGLNRSGLLNDVLQILSNSTKSISTVNAQPTKDMKFANIHVSFGIPNLTHLTTVVEKIKAVPDVYSVKRTNG
>NZ_LR595857.1|WP_046177210.1|223953_224397_+|D-tyrosyl-tRNA(Tyr)-deacylase
MKLVLQRVKEASVSIDGKIAGAINQGLLLLVGVGPDDAAEDLAYAVRKIVNMRIFSDADGKMNQSIQDIKGSILSVSQFTLYADTKKGNRPAFTGAAKPDMANQFYNRFNEQLADFVPVERGVFGADMQVSLINDGPVTIILDTKCH
>NZ_LR595857.1|WP_046177209.1|224494_225817_-|streptokinase
MKNYLSLGMFALLFALTFGTVNSVQAIAGPEWLLDRPSVNNSQLVVSVAGTVEGTNQDISLKFFEIDLTSQPAHGGKTEQGLSPKSKPFATDSGAMSHKLEKADLLKAIQEQLIANVHSNDDYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLSGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFKPVLKDTKLLKTLAIGDTVTSQELLAQAQSILNKNHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYRINKKSGLNEEINNTDLISEKYYVLKKGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMDYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRYTGTPIPDNPNDK
>NZ_LR595857.1|WP_046177224.1|226145_226994_+|PucR-family-transcriptional-regulator
MELKDYFPEMQVGPHPLGDKEWVSIKEGDQYVHFPKSCLSEKERLLLEVGLGQYEVLQPLGSPWQRYLLDHQGNPPQLFETSQFIYLNHQQALPDDLVELLQQMIAGLEVILPISATQTAFLCRQATSIKVLRSLEGLLPTLESDFGLALTMFVGNAWYQVAAGTLRECFEEECQLLTAYLKQKSGGKLLTFAEVMLWSILSHQSFPALTRQFHQFLNPQSDMADVVHALWSEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLHLKQLDDLAFAYLFLLKY
>NZ_LR595857.1|WP_003057915.1|227291_228425_+|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC
MVELNLNHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGKSTTLRMIAGLEDISEGELKIDGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGLKLRKYKKDDIDRRVKEAAEILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMDEPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGNGTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVEVKDGRIVSEDGLDIAIPEGQAKMLETAGYKGKKVTFGIRPEDISSNQIVHDTYPNANVTAEVLVSELLGSETMLYVKLGQTEFASRVDARDFHSPGEQVSLTFNVAKGHFFDLDTEQAIR
>NZ_LR595857.1|WP_022554186.1|228506_230120_+|alpha-glucosidase
MQKQWWHKATIYQIYPRSFKDTSGNGIGDLKGITSQLDYLQKLGITAIWLSPVYQSPMDDNGYDISDYEAIAEVFGNMDDMDDLLAAANERGIKIIMDLVVNHTSDEHAWFVEARENPNSPERDYYIWRDEPNNLMSIFSGSAWELDEASGQYYLHLFSKKQPDLNWENAQLRQKIYDMMNFWIAKGIGGFRMDVIDLIGKIPDSEITGNGPRLHDYLKEMNQATFGNHDVMTVGETWGATPEIARQYSRPENKELSMVFQFEHVGLQHKPNAPKWDYAEELDVPALKTIFSKWQTELKLGEGWNSLFWNNHDLPRVLSIWGNDSIYREKSAKALAILLHLMRGTPYIYQGEEIGMTNYPFKDLTEVDDIESLNYAKEAMENGVPAARVMSSIRKVGRDNARTPMQWSKDTHAGFSEAQETWLPVNPNYQEINVADALANQDSIFYTYQQLIALRKDQDWLVEADYHLLPTADKVFAYQRQFGEETYVIVVNVSDQEQVFAKDLAGAEVVITNTDVDKVLETKHLQPWDAFCVKLSV
>NZ_LR595857.1|WP_046177208.1|230285_233909_+|pullulanase
MIKRVTQGSKQYKYAIKKLSIGVVSVATGASILLYSPQVMAQESSPETGVTQTQVEHEKQATEQADSVVNEAVNASAGLTPESSEKRTEAVGDSSQATEPQLSTNQADASQADKISESAKPLATDAAAKAPAISDNHLRLHLKALPKDQSLDSLGLWVWDDVDQPSKDWPNGAIPLATAKKDDYGYYLDVKLAEKQRKQISYLINNKAGENLSKDQHFQLLTPKMNEVWIDENYHAHAYRPLKKGYLRINYHNQSGHYDNLAVWTFKDVKTPTTDWPNGLDLSHKGPYGVYVDVPLKEGAKEIGFLILDKSKSGDAIKVQPKDYLFKDLDNHTQIFVKDTDPKVYNNPYYIDQVSLKGAEQTTPNEIKAIFTTLDGLDEDTVKQNIKITDKAGKAVAIDELTLDKDKSVMTLKGDFKAQGAVYTVTFGEVSQVARQSWQLKDKLYAYDGELGATLAKDGSVDLALWSPSADSVKVVVYDKQDQTKVVGQADLTKSDKGVWRTHLTSDSIKGISDYTGYYYLYEITRGQEKVMVLDPYAKSLAAWNNATANDQIKTAKAAFVNPSLAGPKDLDFAKINNFKKREDAIIYEAHVRDFTSDPSLDGKLRNEFGTFAAFIEKLDYLKELGVTHVQLLPVLSYFYVNELDKSRSTAYTSSDNNYNWGYDPQHYFALSGMYSANPNDPALRIAELKQLVNEIHKRGMGVIFDVVYNHTARTYLFEDLEPNYYHFMNADGTARESFGGGRLGTTHAMSRRILVDSITYLTREFRVDGFRFDMMGDHDAAAIEQAFKAAKAINPNTIMIGEGWRTYQGDEGKKETAADQDWMKATNTVGVFSDDIRNTLKSGFPNEGTAAFITGGAKNLEGLFKTIKAQPGNFEADAPGDVVQYIAAHDNLTLHDVIAKSINKDPKVAEEEIHKRIRLGNTLILTAQGTAFIHSGQEYGRTKHLLNPDYKTKVADDKVPNKATLIDAVAEYPYFIHDSYDSSDAVNHFDWAKATDGQVNPISYQTQAYTKGLIALRRSSDAFRKASMADVNRDVTLITQAGQGDIQKDDLIIGYQTIASNGDRYAVFVNADSKARTVVLPDRYRHLLGAQVLVDAEQAGVTAIAKPKGVQFTKEGLTIDGLTAIVLKVAAGVVEAPSQTQQARSEQSVRPVSTAVSKASPLMTPYQKPQQASLPQTGEMTSKGLLATGMTMLIAVFGLFTKRQKD
>NZ_LR595857.1|WP_012766514.1|234061_234352_-|hypothetical-protein
MLAQFRPLINRYAKPYLVLVCLLWLAMFFVRWDTMVLGYNLYFLVMQKGFLILGILTILMGAISKRWGLILFGLLFCGAFWINLFIFFGILPVFGN
>NZ_LR595857.1|WP_003057937.1|234507_234858_+|conjugal-transfer-protein-TraF
MTFEETIAQFTTVEIGEVKQAIENGKDMIVFLGRSTCPFCRLFAPKLAQVAEDHQKKVFFVNSENPIDAEALQAFRQEYHLATVPALLVIHSGQVRAVCDSSLTESEILDFLTTRE

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Crispr_ID: NZ_LR595857_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LR595857_2

882677-882775

TypeII

II-A,II-B

Consensus_repeat	Method
GTTTTAGAGCTATGTTGTTTTGAATGGTCCCAA	CRISPRCasFinder

1 spacers

csn2,cas1,cas9

The CRISPR arrays of NZ_LR595857_2

>merge|NZ_LR595857|2|882677-882775|CRISPRCasFinder
GTTTTAGAGCTATGTTGTTTTGAATGGTCCCAAAACTTGCTCTTATCTTTTATCCGTTTTTAGATAGTTTTAGAGCTATGTTGTTTTGAATGGTCCCAA

>NZ_LR595857|2|2|882677-882775|CRISPRCasFinder
GTTTTAGAGCTATGTTGTTTTGAATGGTCCCAA	AACTTGCTCTTATCTTTTATCCGTTTTTAGATA
GTTTTAGAGCTATGTTGTTTTGAATGGTCCCAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LR595857.1\|WP_046177083.1\|870665_872021_+\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NZ_LR595857.1\|WP_003054515.1\|874739_875504_+\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_LR595857.1\|WP_143936374.1\|876609_880725_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_LR595857.1\|WP_003058434.1\|890372_890864_+\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|225976
NZ_LR595857.1\|WP_003058439.1\|883421_885254_+\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_LR595857.1\|WP_046177076.1\|888701_889721_+\|YeiH-family-putative-sulfate-export-transporter	unknown	unknown	gnl\|CDD\|225411
NZ_LR595857.1\|WP_046177081.1\|872847_873978_+\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_LR595857.1\|WP_015017090.1\|887421_888591_+\|DUF2974-domain-containing-protein	unknown	unknown	gnl\|CDD\|371412
NZ_LR595857.1\|WP_046177075.1\|890880_891690_+\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226238
NZ_LR595857.1\|WP_041789030.1\|875503_876133_+\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
NZ_LR595857.1\|WP_003058441.1\|886935_887232_+\|bacteriocin-immunity-protein	unknown	unknown	gnl\|CDD\|370205
NZ_LR595857.1\|WP_046177108.1\|881911_882574_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_LR595857.1\|WP_003058431.1\|886705_886936_+\|bacteriocin	unknown	unknown	gnl\|CDD\|366773
NZ_LR595857.1\|WP_003062486.1\|885429_885867_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_LR595857.1\|WP_003058453.1\|889927_890353_+\|PTS-mannose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
NZ_LR595857.1\|WP_003056616.1\|869655_870612_+\|YbbR-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|227193
NZ_LR595857.1\|WP_046177080.1\|873987_874740_+\|acyl-[acyl-carrier-protein]-thioesterase	unknown	unknown	gnl\|CDD\|226401
NZ_LR595857.1\|WP_046177077.1\|880724_881594_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_LR595857.1\|WP_046177082.1\|872144_872786_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LR595857.1\|WP_003060137.1\|882893_883352_+\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|179085

Protein	Function_ID	Function_description	E-value
NZ_LR595857.1\|WP_046177083.1\|870665_872021_+\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_LR595857.1\|WP_003054515.1\|874739_875504_+\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.34174e-127
NZ_LR595857.1\|WP_143936374.1\|876609_880725_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_LR595857.1\|WP_003058434.1\|890372_890864_+\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	gnl\|CDD\|225976	COG3444, COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB [Carbohydrate transport and metabolism].	2.69664e-54
NZ_LR595857.1\|WP_003058439.1\|883421_885254_+\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_LR595857.1\|WP_046177076.1\|888701_889721_+\|YeiH-family-putative-sulfate-export-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	6.01185e-103
NZ_LR595857.1\|WP_046177081.1\|872847_873978_+\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_LR595857.1\|WP_015017090.1\|887421_888591_+\|DUF2974-domain-containing-protein	gnl\|CDD\|371412	pfam11187, DUF2974, Protein of unknown function (DUF2974). This bacterial family of proteins has no known function.	1.98334e-78
NZ_LR595857.1\|WP_046177075.1\|890880_891690_+\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	gnl\|CDD\|226238	COG3715, ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism].	6.524e-77
NZ_LR595857.1\|WP_041789030.1\|875503_876133_+\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	1.94922e-80
NZ_LR595857.1\|WP_003058441.1\|886935_887232_+\|bacteriocin-immunity-protein	gnl\|CDD\|370205	pfam08951, EntA_Immun, Enterocin A Immunity. Gram-positive lactobacilli produce bacteriocins to kill closely-related competitor species. To protect themselves from the bacteriocidal activity of this molecule they co-express an immunity protein (for discussion of this operon see Bacteriocin_IIc pfam10439). The immunity protein structure is a soluble, cytoplasmic, antiparallel four alpha-helical globular bundle with a fifth, more flexible and more divergent C-terminal helical hair-pin. The C-terminal hair-pin recognizes the C-terminus of the producer bacteriocin and this interaction is sufficient to dis-orient the bacteriocin within the membrane and close up the permeabilising pore that on its own the bacteriocin creates. These immunity proteins interact in the same way with other bacteriocins, family Bacteriocin_II, pfam01721. Since many enterococci can produce more than one bacteriocin it seems likely that the whole operon can be carried on transferable plasmids.	0.000236171
NZ_LR595857.1\|WP_046177108.1\|881911_882574_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	7.24276e-123
NZ_LR595857.1\|WP_003058431.1\|886705_886936_+\|bacteriocin	gnl\|CDD\|366773	pfam01721, Bacteriocin_II, Class II bacteriocin. The bacteriocins are small peptides that inhibit the growth of various bacteria. Bacteriocins of lactic acid bacteria may inhibit their target cells by permeabilising the cell membrane.	2.52035e-05
NZ_LR595857.1\|WP_003062486.1\|885429_885867_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	2.05206e-85
NZ_LR595857.1\|WP_003058453.1\|889927_890353_+\|PTS-mannose-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	4.42496e-29
NZ_LR595857.1\|WP_003056616.1\|869655_870612_+\|YbbR-like-domain-containing-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	6.1821e-105
NZ_LR595857.1\|WP_046177080.1\|873987_874740_+\|acyl-[acyl-carrier-protein]-thioesterase	gnl\|CDD\|226401	COG3884, FatA, Acyl-ACP thioesterase [Lipid metabolism].	7.04528e-106
NZ_LR595857.1\|WP_046177077.1\|880724_881594_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	7.18372e-130
NZ_LR595857.1\|WP_003060137.1\|882893_883352_+\|nucleoside-diphosphate-kinase	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	5.05917e-75

>NZ_LR595857.1|WP_046177108.1|881911_882574_+|type-II-A-CRISPR-associated-protein-Csn2
MNLNFPLLDEPIPLRGGTILVLEDVCVFSKIVQYCYQYEEDSELKFFDHKMKTIKESEIMLVTDILGFDVNSSTILKLIHADLESQFNEKPEVKSMIDKLVATITELIVFECLENELDLEYDEITILELIKSLGVKVETQSDTIFEKCLEILQIFKYLTKKKLLIFVNSGAFLTKDEVASLQEYISLTNLTVLFLEPRKLYDFPQYILDKDYFLITKNMV
>NZ_LR595857.1|WP_046177077.1|880724_881594_+|type-II-CRISPR-associated-endonuclease-Cas1
MAGWRTVVVNTHSKLSYKNNHLIFKDAYKTELIHLSEIDILLLETTDIVLSTMLVKRLVDENVLVIFCDDKRLPTAMLMPFYGRHDSSLQLGKQMSWSEEVKSEVWTTIIAQKILNQSCYLGACSYFEKSQSIMDLYHGLELFDPSNREGHAARIYFNTLFGNDFSREQDNAINVGLDYGYTLLLSMFAREVVVSGCMTQFGLKHANQFNQFNFASDIMEPFRPLVDKIIFENRNQPFPKIKRELFTLFSDTFLYNGKEMYLTNIVSDYTKKVVKALNNEGKGVPEFRI
>NZ_LR595857.1|WP_143936374.1|876609_880725_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MDKKYSIGLDIGTNSVGWAVITDDYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRIRYLQEIFSSEMSKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKELADSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASRVDAKAILSARLSKSRRLENLIAQLPGEKRNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRVNSEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLAKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGIEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDKEMIEERLKTYAHLFDDKVMKQLKRRHYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFIQLIHDDSLTFKEAIQKAQVSGQGHSLHEQIANLAGSPAIKKGILQSVKVVDELVKVMGHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFIKDDSIDNKVLTRSDKNRGKSDDVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIGKATAKRFFYSNIMNFFKTEITLANGEIRKRPLIETNEETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGALTNESIYARGSFDKLISRKHRFESSKYGGFGSPTVTYSVLVVAKSKVQDGKVKKIKTGKELIGITLLDKLVFEKNPLKFIEDKGYGNVQIDKCIKLPKYSLFEFENGTRRMLASVMTNNNSRGDLQKANEMFLPAKLVTLLYHAHKIESSKELEHEAYILDHYNDLYQLLSYIERFASLYVDVEKNISKVKELFSNIESYSISEICSSVINLLTLTASGAPADFKFLGTTIPRKRYGSPQSILSSTLIHQSITGLYETRIDLSQLGGD
>NZ_LR595857.1|WP_041789030.1|875503_876133_+|TIGR01906-family-membrane-protein
MVENTKLLCSWLWLLALAILMTIYSAWLWYPLEVDHLKLEQVVFMSKDAILHNYNGLLNYLTNPFETSLTFASFRSSTDGLKHFADVKWLFHLTQVVFLGLLYPTVKDFKQRFKTKSFWSIQRPLMIAALFPLMIGLMASVIGFENFFTLFHKVLFVGDSNWLFDPLKDPVIWILPEVFFLHCFLFFMTVYEIILWSLVGLARWQRPKI
>NZ_LR595857.1|WP_003054515.1|874739_875504_+|TIGR01457-family-HAD-type-hydrolase
MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQEKGLPYLLVTNNTTRTPEMVQDMLSKQFNVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIAAAGYVEELENPAYVVVGLDSQVTYDMLATATLAIQKGALFIGTNPDLNIPTERGLMPGAGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQNDIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL
>NZ_LR595857.1|WP_046177080.1|873987_874740_+|acyl-[acyl-carrier-protein]-thioesterase
MGLSYREDIKLPFELCDVKSDIKFPLLLDYCLTVSGRQSAQLGRSNDYLLEQYGLIWIVTDYEATIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGCLLVDILAYFALLNPDTRKVATIPEDLVAPFETDFVKKLHRVPKMPLLEQSIDRDYYVRYFDIDMNGHVNNSKYLDWMYDVLGYEFLKAHEPLRMTLKYVKEVSPGGQITSSYHLDQLTSYHQITSDGQLNAQAMIEWRAIKQTESEID
>NZ_LR595857.1|WP_046177081.1|872847_873978_+|oxygen-independent-coproporphyrinogen-III-oxidase
MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLEALIQEFESYDIHDLKTLYIGGGTPTAITAAQLEYLLSHLERNLNLGYLEEFTIEANPGDLTPDKIEVLKHSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKTAGFHNISIDLIYALPGQTLAQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQNRVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGISFEECYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD
>NZ_LR595857.1|WP_046177082.1|872144_872786_+|hypothetical-protein
MTKQQIEKLADLLPPFAAKLYLDMIPEFQEGYASYVYQTQKEDTQKRRIKQLTKSFARFLDTPSFYVMPLSVQVGKQLLRNEEIACHSLSSVEAIQAFEAAVEDEKEVLQLLRNGSRLALLVLEEANETVHMDLGILTKVEQKVISPAMLTAIEEYLLATTEGNALQLTVTVEQGAARTFYQAHGFHQKADDLVFKPTDGKLICQMVKDLFKA
>NZ_LR595857.1|WP_046177083.1|870665_872021_+|phosphoglucosamine-mutase
MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPKDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGIGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRHSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLTKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKERAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN
>NZ_LR595857.1|WP_003056616.1|869655_870612_+|YbbR-like-domain-containing-protein
MKRFLNSRPWLGLVSVFFAILLFLTAASSNHNNSGSQTYSPIETYTHSLKDVPIDMKYDSEKYFISGYSYGTEVYLTSTNRVKLDSEVNSDTRSFKIVADLTKSHPGTATVDLKVENLPSGVTATVSPDKISVIIGKKESKMFPVRGAVDAKQIANGYEINKIETGIDKVEVTSDESTIALIDHVVAKLPDDQVLDANYSSRVTLQAVSADGTILASAIDPAKANLSVGVKRITKSVPIRVEAVGVMDDRLSDIQYKLSKQTALISGSREALEAIDEIVAEVNISDVTKNTSKTVSLSSSQVSIEPSVVTVQLTTTKK
>NZ_LR595857.1|WP_003060137.1|882893_883352_+|nucleoside-diphosphate-kinase
MEQTFFMIKPDGVERGLVGEVLRRIERRGFTFERLELRQASPELLAKHYEALVTKPFYPELEAYMTSGPVLIGVLSGNRVISSWRTMMGVTNPKDALPGTIRGDFAQAPGDDGGIFNVVHGSDSRDSARREIALWFNQAELDSSAIFPKDNQ
>NZ_LR595857.1|WP_003058439.1|883421_885254_+|elongation-factor-4
MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDGDMIEVSNPSEFPDPTRVASIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYEISEYRKSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVSRSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEDAKK
>NZ_LR595857.1|WP_003062486.1|885429_885867_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
METKDDLKKRIGDLSYEVTQHAATERPFTGKYDDFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHVFSDGPQEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDEK
>NZ_LR595857.1|WP_003058431.1|886705_886936_+|bacteriocin
MNTKIFEKFDFMDNEKLAYIDGGAGSGKTVYQGNGLYCNKVKCWVNWAETWTTIANNSVMNVLTGGNAGWHSGGAL
>NZ_LR595857.1|WP_003058441.1|886935_887232_+|bacteriocin-immunity-protein
MSGLNWFSGGNERQQQASLLIKDLVADLKQSGGKEPLQKVLLSFDEELKRGESSIPFILSRMTVAVSTVLKEHQITLSAKESDQLDDLYALLQIRYGY
>NZ_LR595857.1|WP_015017090.1|887421_888591_+|DUF2974-domain-containing-protein
MATLLDYIKTNGHRDYHSLALNELDVAVINEIGYLTFDELVADDNHLEATIKLSQLPLLQTREIKGTPYDFLNTKERLDLFQMMCQSKRFSELTLSHYINDINTEFEKQFAAMVFRLPSIDYTQLVFRGTDDSLIGWKEDFKLTYMREIPAHRSAIDYLKTYHTYYPNQKLVLSGHSKGGNLALYAASFVPKNVQASLKDIYLFDSPGLIKEFLTHPGYQAIRRRLVVIKPQDAIIGVMLYCDVPEKIVQSQSYGLLQHQMVNWQITPNAQFKRAPKRSALSYDLEETFKDWTNQLSKQDLKLLCDTFFDCLASSGITSLNAFSLDDKAFLTLMRVISSLQSIDHEKKKVMVKSLHQLMVTYGSYRRRDISENIHNRLQQLLTLTKGIK
>NZ_LR595857.1|WP_046177076.1|888701_889721_+|YeiH-family-putative-sulfate-export-transporter
MSTYLRKLPGLLLCLLLALPAWYLGRLFPIIGAPVFAILLGMLLALFYHHRDKTKEGISFTSKYILQTAVVLLGFGLNLTQIMAVGMQSLPIIVSTVATALLVAYGLQKWLGLDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEIAKAISVIFLFNILAALLFPSLGQLLGLSNEGFAIFAGTAVNDTSSVTATATAWDAIHHSNTLDGATIVKLTRTLAILPITLGLSLYRAKKEHDIVTEEGFSLRKSFPRFILFFLLASLITTLMTNFGVSADVFHSLKELSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLGMQFALGIW
>NZ_LR595857.1|WP_003058453.1|889927_890353_+|PTS-mannose-transporter-subunit-IIA
MKRKFLIGSHGRLASGLQSSIDILAGMGQSLEIIDAYVDDSDYTSQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMASGKDNIFLITNSNLATLLSVMFLNPDEALTKDKIVTVINESQVQLVDLSPATDSEDDFFD
>NZ_LR595857.1|WP_003058434.1|890372_890864_+|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB
MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQMTLKMAVPNGMKLLIRSVEESIKLFNDPRAKDKRIFVIVNSVKDACAIAKEVPDLEAVNVANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQLVN
>NZ_LR595857.1|WP_046177075.1|890880_891690_+|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC
MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDMKVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGMLAAFVVMFLKNVFMNIFAPMVDKAAEANHQGKLVMLHYGTWIIYYLIIASISFIGILVGSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYLKLPAVAVAALGAVICVISSQRDLELDAITKGAFSNQTNFDSKESEEEDFFA

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Crispr_ID: NZ_LR595857_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LR595857_3

1451360-1451588

TypeI

NA:I-C

Consensus_repeat	Method
ATTTCAATCCACTCACCCGCGAAGGGTGAGAC	CRT
CAATCCACTCACCCGCGAAGGGTGAGAC	CRISPRCasFinder
AATTTCAATCCACTCACCCGCGAAGGGTGAGAC	PILER-CR

3 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of NZ_LR595857_3

>merge|NZ_LR595857|3|1451360-1451588|CRT,CRISPRCasFinder,PILER-CR
GATGCAATCCACTCACCCGCGAAGGGTGAGACATGATGTCTTTACGGTGGTCGACAGTACTAAAGAATTTCAATCCACTCACCCGCGAAGGGTGAGACGCGTACATAAACGAAGCGACATTAGCGAATAAAATTTCAATCCACTCACCCGCGAAGGGTGAGACCGTGTATGTCTGTGTGACCTGCACCAAGGTAGGTATTTCAATCCACTCACCCGCGAAGGGTGAGAC

>NZ_LR595857|3|1|1451360-1451588|CRT
GATGCAATCCACTCACCCGCGAAGGGTGAGAC	ATGATGTCTTTACGGTGGTCGACAGTACTAAAGA
ATTTCAATCCACTCACCCGCGAAGGGTGAGAC	GCGTACATAAACGAAGCGACATTAGCGAATAAA
ATTTCAATCCACTCACCCGCGAAGGGTGAGAC	CGTGTATGTCTGTGTGACCTGCACCAAGGTAGGT
ATTTCAATCCACTCACCCGCGAAGGGTGAGAC

>NZ_LR595857|3|3|1451364-1451588|CRISPRCasFinder
CAATCCACTCACCCGCGAAGGGTGAGAC	ATGATGTCTTTACGGTGGTCGACAGTACTAAAGAATTT
CAATCCACTCACCCGCGAAGGGTGAGAC	GCGTACATAAACGAAGCGACATTAGCGAATAAAATTT
CAATCCACTCACCCGCGAAGGGTGAGAC	CGTGTATGTCTGTGTGACCTGCACCAAGGTAGGTATTT
CAATCCACTCACCCGCGAAGGGTGAGAC

>NZ_LR595857|3|1|1451425-1451588|PILER-CR
AATTTCAATCCACTCACCCGCGAAGGGTGAGAC	GCGTACATAAACGAAGCGACATTAGCGAATAA
AATTTCAATCCACTCACCCGCGAAGGGTGAGAC	CGTGTATGTCTGTGTGACCTGCACCAAGGTAGG
TATTTCAATCCACTCACCCGCGAAGGGTGAGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LR595857.1\|WP_046177341.1\|1460167_1462816_-\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_LR595857.1\|WP_143936393.1\|1457477_1459901_-\|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_LR595857.1\|WP_046177337.1\|1443977_1445711_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NZ_LR595857.1\|WP_012767323.1\|1463377_1463968_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_LR595857.1\|WP_046177336.1\|1442825_1443905_-\|MmcQ/YjbR-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|225197
NZ_LR595857.1\|WP_015057910.1\|1453738_1454587_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175
NZ_LR595857.1\|WP_041789086.1\|1462817_1463381_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379082
NZ_LR595857.1\|WP_012767318.1\|1449250_1450183_-\|magnesium-transporter-CorA-family-protein	unknown	unknown	gnl\|CDD\|213361
NZ_LR595857.1\|WP_012767317.1\|1448320_1449031_-\|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2	unknown	unknown	gnl\|CDD\|223856
NZ_LR595857.1\|WP_014612478.1\|1456486_1457215_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_LR595857.1\|WP_003057398.1\|1441444_1441918_+\|arginine-repressor	unknown	unknown	gnl\|CDD\|224355
NZ_LR595857.1\|WP_003044506.1\|1451736_1452030_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|224262
NZ_LR595857.1\|WP_003055983.1\|1446535_1447642_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|184456
NZ_LR595857.1\|WP_015057909.1\|1453062_1453737_-\|CRISPR-associated-protein-Cas4	cas4	COG1468_cas4_CAS-I-A:CAS-I-B:CAS-I-C:CAS-I-D:CAS-II-B	gnl\|CDD\|224385
NZ_LR595857.1\|WP_011184771.1\|1445707_1446448_-\|response-regulator	unknown	unknown	gnl\|CDD\|227095
NZ_LR595857.1\|WP_046177338.1\|1447684_1448308_-\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
NZ_LR595857.1\|WP_041789084.1\|1450274_1451234_-\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_LR595857.1\|WP_046177340.1\|1454591_1456487_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	gnl\|CDD\|187773
NZ_LR595857.1\|WP_003057390.1\|1442095_1442812_-\|B3/4-domain-containing-protein	unknown	unknown	gnl\|CDD\|225917
NZ_LR595857.1\|WP_046177339.1\|1452040_1453066_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360

Protein	Function_ID	Function_description	E-value
NZ_LR595857.1\|WP_046177341.1\|1460167_1462816_-\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_LR595857.1\|WP_143936393.1\|1457477_1459901_-\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.80275e-158
NZ_LR595857.1\|WP_046177337.1\|1443977_1445711_-\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	2.95557e-62
NZ_LR595857.1\|WP_012767323.1\|1463377_1463968_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	2.13757e-33
NZ_LR595857.1\|WP_046177336.1\|1442825_1443905_-\|MmcQ/YjbR-family-DNA-binding-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	3.80234e-32
NZ_LR595857.1\|WP_015057910.1\|1453738_1454587_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	2.68212e-160
NZ_LR595857.1\|WP_041789086.1\|1462817_1463381_-\|AAA-family-ATPase	gnl\|CDD\|379082	pfam13238, AAA_18, AAA domain.	0.000983152
NZ_LR595857.1\|WP_012767318.1\|1449250_1450183_-\|magnesium-transporter-CorA-family-protein	gnl\|CDD\|213361	cd12827, EcCorA_ZntB-like_u2, uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family. A uncharacterized subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB (EcCorA-ZntB_like) family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes.The EcCorA-ZntB-like family includes the Mg2+ transporters Escherichia coli and Salmonella typhimurium CorAs, which can also transport Co2+, and Ni2+. Structures of the intracellular domain of EcCorA-ZntB-like family members, Vibrio parahaemolyticus and Salmonella typhimurium ZntB, form funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport through Salmonella typhimurium CorA. Natural variants such as GVN and GIN, such as occur in some ZntB family proteins, may be associated with the transport of different divalent cations, such as zinc and cadmium. The functional diversity of MIT transporters may also be due to minor structural differences regulating gating, substrate selection, and transport.	6.77731e-80
NZ_LR595857.1\|WP_012767317.1\|1448320_1449031_-\|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2	gnl\|CDD\|223856	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones].	2.60557e-42
NZ_LR595857.1\|WP_014612478.1\|1456486_1457215_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	1.61143e-116
NZ_LR595857.1\|WP_003057398.1\|1441444_1441918_+\|arginine-repressor	gnl\|CDD\|224355	COG1438, ArgR, Arginine repressor [Transcription].	3.49174e-65
NZ_LR595857.1\|WP_003044506.1\|1451736_1452030_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|224262	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms].	2.32373e-34
NZ_LR595857.1\|WP_003055983.1\|1446535_1447642_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|184456	PRK14018, PRK14018, bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB.	1.44907e-162
NZ_LR595857.1\|WP_015057909.1\|1453062_1453737_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|224385	COG1468, COG1468, CRISPR-associated protein Cas4 (RecB family exonuclease) [Defense mechanisms].	9.21685e-41
NZ_LR595857.1\|WP_011184771.1\|1445707_1446448_-\|response-regulator	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	2.46705e-83
NZ_LR595857.1\|WP_046177338.1\|1447684_1448308_-\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	9.04791e-36
NZ_LR595857.1\|WP_041789084.1\|1450274_1451234_-\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.46059e-57
NZ_LR595857.1\|WP_046177340.1\|1454591_1456487_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187773	cd09642, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-C subtype; also known as Csd1 family.	0
NZ_LR595857.1\|WP_003057390.1\|1442095_1442812_-\|B3/4-domain-containing-protein	gnl\|CDD\|225917	COG3382, COG3382, Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only].	3.47496e-105
NZ_LR595857.1\|WP_046177339.1\|1452040_1453066_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0

>NZ_LR595857.1|WP_041789084.1|1450274_1451234_-|Gfo/Idh/MocA-family-oxidoreductase
MAKVRYGIVSTAQVAPRFIEGMRLAGNGEVVAVSSRSLDKAKAFAAAHQLPKAYGSLDDMLLDASIDAIYVASINQDHFPAAKKALLAGKHVLVEKPFTLTAAQAEELFALAQEHGLFLMEAQKAVFIPMTQRLKGLIAAGELGDIVSVSSTTAYPNIDHVTWFRDLEKGGGTVHFMAPYALSYLPYLFDADIVSASGVAHFPKGQSDSQSKLVLALSNGVLVDIFLTTHLSLPHELVIYGTKGRLEIPHFWKTTHATLVRPDGSRSVIEATMFSDFEAEAHHVSQMILEGQLTSPVMTKSLTLSGVGLIEKLYRSWGK
>NZ_LR595857.1|WP_012767318.1|1449250_1450183_-|magnesium-transporter-CorA-family-protein
MPTLPKASSAITLINLDQLTEHDQEALVSEGLIDAEVFDYAKDKNETSFMEENKEKLTIVFQILDRQEEAYHPNHIPRVIPITLFLNDQSLYILGHDHSLTLIEEVFPDLDESRSPRHLVFQLLTAFTKQYVPLMDEIAQQRDKLIEALRQKANKTNLESLANLQSGTVYILMGSKQNEQMLAELKNMPGQQDLEEDEAEQLRDAIIEARQLSNMCDLNTRVLKEISSSYNNVLSNNLNNNVTSLTIFSIGISIIAMVTSFYGMNVKLPFAKVDSVWFWIVLTTSLVALLIMVVMYWYVHKRNRNASKRI
>NZ_LR595857.1|WP_012767317.1|1448320_1449031_-|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2
MTLSIVLIASVFAAGLLSFFSPCIFPVLPVYLGILLDADDSRTMTIFGKKLYWYGIVKTIAFIFGLSTIFVILGYGAGFLGNILYAVWFRYFLGALVIILGIHQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVASGGNGAWQGGLLMIVYTLGLGIPFLLLSFASGFVLKHFNKLKPHMFLLKKVGGVLIIIMGILLMTGTLNNLAQLFG
>NZ_LR595857.1|WP_046177338.1|1447684_1448308_-|TlpA-family-protein-disulfide-reductase
MKKGLLVTTALACLGLLTACSAQDNMAKKEMTQDKMSMATKTNDKMSTSKDKSMTTDKSSDKKMTNEGPMAPDFELKSVDGKTYRLSDLKGKKVYLKFWASWCSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFRKWFQGTDYKGLPVLLDPDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH
>NZ_LR595857.1|WP_003055983.1|1446535_1447642_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKKVKSTKVDPNVPVDQKVIYLAGGCFWGVEEYFSQVNGVLDAVSGYANGRGDTTNYQLIHQTGHAETVEVTYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADLAIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPVIDESKYPKPSATEIKAKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLFSSKDKFESGCGWPSFSRPISPDVIRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKDQGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE
>NZ_LR595857.1|WP_011184771.1|1445707_1446448_-|response-regulator
MYSLLIVEDEYLIRQGIRSLVDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPKLNGIQLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKADVEDMLGKLQQKLDLSKKTETIQELVEQPQKEVSAIAMAIHERLADSDLTLKSLAQQLGFSPNYLSVLIKKELGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVGFEDMNYFSQRFKQLVGVTPSQYKKGGQA
>NZ_LR595857.1|WP_046177337.1|1443977_1445711_-|sensor-histidine-kinase
MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERDTRQSIRQSSQFIDAYIKPLKETTSVLAKNSEIQAFASQIHQENDKQVLQLMKMVLATNSDLQAAVLVTKDGRTVSTNPQLIMKTSSDMMAEPWYKAAIDRQSMPILTPARQLSLSSKKEWVVSVTQEVVDAAGHNLGVLRLDIAYPTIEASLDQLQLGRQGFAFIVNDKHEFVYHPKKSVYSSSKEMAAMKPYLAIKNGYAKDKSSFVYQRVIPNSQWTLIGVASLDQLHRVQRQIFWSFLGTGLLACLICGFATVLALRRWIRPIQQLQQVILAIQKGDRQLRAQETGSPELTDLAHQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKRVVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYDVQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKITVSDTAQHLMLTVWDNGKGIEDSSLTNSQSLLARGGVGLKNVDQRLKLHYGEGYHMTIHSQSDHFTEIQLSLPKMHELMADDTQENE
>NZ_LR595857.1|WP_046177336.1|1442825_1443905_-|MmcQ/YjbR-family-DNA-binding-protein
MSLATDYFSRQTPIVEKLVAYGFEKRDNGYFYNERFMEGEFEAQLRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLERLSVACFEVTPFQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVGGKWYAMIFSLLADKLDQIPERLVGQTCEVMTVKVNPKDLPQLLQQEGIYPAYHMSKNNWVSVVLDDKVTDDQLWGLATQSRQLVNPNGLSNPNSPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYITAPVKSIRYACQVLETDIPNEGYRKNPNIDKLMRLRKCQQYKDGLLSLDLMKEHGVAAVRGPRRLSPQLIAFLKEKEYFKENN
>NZ_LR595857.1|WP_003057390.1|1442095_1442812_-|B3/4-domain-containing-protein
MVEFVADQSFWELFPDAKLGVVLLKDVQNQAESPEDVKQLLADSHELAKAYLTADNFSDNQVVQVYRKAYQHFKTKKGARSSIEALLKRVSNGQSIPSINPLVDIYNAASLRFGLPVGAEDSDSFIGDLRLTITDGGDDFYLIGDADNNPTLPNELCYKDDIGAVCRCLNWRDGERTMVTEHTKNAFLIIEALDQEGQNRLQEALKFIEGSAKMYLHAITSLHMLDKDNPHVPLFTEN
>NZ_LR595857.1|WP_003057398.1|1441444_1441918_+|arginine-repressor
MNKKETRHQLIRSLISETTIHTQQELQERLRKNGITITQATLSRDMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKVVQHQIILKTLPGLAQSFGSILDAMQIPEIVATVCGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK
>NZ_LR595857.1|WP_003044506.1|1451736_1452030_-|CRISPR-associated-endonuclease-Cas2
MMVLVTYDVNTETSAGRKRLRHVAKLCVDYGQRVQNSVFECSVTPAEFVDIKHRLTQIIDGETDSIRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL
>NZ_LR595857.1|WP_046177339.1|1452040_1453066_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLYLTQEDFYVTKEGDNIVIKQEGKVLKRFPFRIIDGIVCFSYLGVSPALVKLCTENQINLSFHTPQGRFCGRYIGSTNGNVLLRREHYRLSDREESLEYAKRFILAKISNSRKYLLRFKRDHRQQIDTTLFEAVNDELIWALGMVQAADNKDSLRGIEGQAANQYFRIFNDLVLTNKKTFYFQGRSKRPPLDCVNALLSFGYSLLTFECQSALEAVGLDSYVGFFHTDRPGRASLALDLVEEFRSYIVDRFVFSLINKGQLQKKHFEFKENGSILLTENGRAIFIDLWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDLESYPPFMV
>NZ_LR595857.1|WP_015057909.1|1453062_1453737_-|CRISPR-associated-protein-Cas4
MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQILHTKADNPYIKEKRKDLLVSRAMPISSAELGLSGIMDVVEFYKDDQGVSLRGKRGKWLPKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLGCHINEGCLYYHSVNQRVTVEMTSALRQEVRELTTEMHKVYQSQMLPKAAYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMTSEEMNL
>NZ_LR595857.1|WP_015057910.1|1453738_1454587_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSIKRKIRNRLQDMGKSIFVQANERIEDDFRSLERRFSQHFTAKTPDKEIEEKANALWFDVRAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNNSGRSSDTMGTKHFVDYGVYVLKGSINAYFAEKTGFSQEDAEAIKEVLVSLFENDASSARPEGSMRVCEVFWFTHSSKLGNVSSARVFDLLEYHQSIEEKSTYDAYQIHLNQEKLAKYEAKGLTVEILEGL
>NZ_LR595857.1|WP_046177340.1|1454591_1456487_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MDFFTSLLKTYEKAELADLVDHQKRNNEPVLLPLYHTSLKSNGKNIISVKLDKDGQFHKAEFMADKQMIIFPVTADSVARSGSHPAPHPLVDKFAYYSAEMGQTQYDSFHKQLNNWIDYCEEGDVKRFLTIVQQFILKPEFLTLILDSLIGPDYQHNQLKVTFCDATGKEKLIDLSACFLEFSIDQFQGFKNESVSTFKALHQSYISFVEANRENLGICNISGREEQLTDKHRGLMGNAKIISVSNKREAYKGRFREREDVFSVGYETSEKIHLMIKYLLENKNTSTWLGSSQYLINWFSDDLTNDSRLDIVSPIFDDGLEEDDDDDTPPVIALATEDNKRIGKSFIKGQKLFANDATYYVAILNKTSNGRIALKYFRQLQASQLLTNLDKWQETYSWESRSKFGKSRLRTPTFHDILNVSYGVDRDRFLELDNDNFKSDQIQKLVASLIDGKPMPQSIVKKLGNNVKERHRYRKHWYQVEQVCLAILHKQNGEEFSPMLDHTNQNRSYLFGRLLAIFELIETLRYGLDGNNNDRITNAERYWTAYTGQPTKLMMLLENKIKPYEEPLKLNRRGSWMKLEKEKEEILELLNPLLETETMEKPLDYRFIFGYYAEKNYYYTKQNTEVTESEE
>NZ_LR595857.1|WP_014612478.1|1456486_1457215_-|type-I-C-CRISPR-associated-protein-Cas5
MYKSRDFYVRVSGQRALFTNPATKGGSERASYSVPTRQALNGIVDAIYYKPTFTNIVTEVKIINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFVWNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRECLGLVDDISQEEYETTVSYYNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVITFKAQSECDIVNTLSSYAFKAPEEIKSVNDECMEYDAMEKGEN
>NZ_LR595857.1|WP_143936393.1|1457477_1459901_-|CRISPR-associated-helicase-Cas3'
MMTKQTLAHYQKKTEQESEKKQSLDEHLWHVACSSRQEASIIGQGDVLFLIGLYHDLGKADRAFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMTFNEMVGYVISAHHGMYDLCYSSDDAEYYSFNKFKNRINRDLDGYHYHEDIKGYALKLEEKLCDYGYKDLRELIDKAFDNYQQAMSSLNWQDKSEWDYYQSCMVRLYLSLLKNADILDTVNAYGLKISPMDKTERSFLKHSYLAAIEQKYASFGRPNNQLNIIRTEIAERVKERGKRDSKGIYRLDLPTGAGKTNLSMRYAFHQLVHQDKSRFFYITPFLSVLEQNASEIRKVTGDLGVLEHHSNMVKQANEDDDKDSLLSAYLIDSWDSQVVLTSMVQFFQTLFKTKSANLRRFSSLINSVVILDEVQSLPIEVTTLFNLTMNFLNKVMDTTIVLCTATQPAYDSSEIDHRICYGGNLGELAEIVELTIEEKQIFSRTELRKFDDSDQKVYLTDVINLILGEENSVLAIFNTKKTVHNCYTMLKDMTDRPIYQLSTNMCAQHRLDLVAKIKTELQNNTPIICISTQLIEAGVDVDFHRVIRSYSGIDSIVQAAGRCNREGKRDKGQVTLVNLTNEEENISRLTEIKAKKEATESILHKIGSPIDISTLNRDFFEYYYANNQGLMDYPLEDNLSIYDYLSLNIYQTANKKFKGKLKQAFKTAGAKMNLINNDMIGILVPYGVAKKKLAYLEELGASHFLSAENYQTIKSLLKDLQPFTVNVRENDPLLEATKTYLNGQILVLTSEYYDTERGVKYDSASFYF
>NZ_LR595857.1|WP_046177341.1|1460167_1462816_-|valine--tRNA-ligase
MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGISRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFVDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATTRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIVNKLIPIVGDEHADPEFGTGVVKITPAHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVNIEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDNRVDFYPPRFNDTFLQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSALWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDASWNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASDAGNVTDQWILHNLNETIAKVTENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKILRLLHPIMPFVTEEIYAQYAQGSIVTAAYPTVTPAFENEAAHKGVESLKDFIRAVRNARAEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSIITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVVQKEKDKQADYQAKYDATQERIVEMQKLVG
>NZ_LR595857.1|WP_041789086.1|1462817_1463381_-|AAA-family-ATPase
MNLIIIGAQASGKMTIGQEIAEQTGMTLFHNHDSIDFVLRFMPWSQESTALIERLRFNFFETFAKNGQEMIFTIVIDFNDPNDVAFLDKIQAVFQSYDQEVLFVELETDVNERLKRNRTENRLKHKPFKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTHYQKINNTHLTAAETAQLIIQKMTHIKEN
>NZ_LR595857.1|WP_012767323.1|1463377_1463968_-|GNAT-family-N-acetyltransferase
MIVKMLEAYNGKALPKVETERLVLRQRKLEDAEDIFAFAKLAEVSYPAGFPPVKSLADEITYLQDIYPANLEKEGLPSGYGITLKGDDKVIGSIDFNHRRADDVFEIGYLLHPDYWGQGIVPEAAAALIEIGFTLIDLHKIELGCYDYNKQSQAVARKLGFILEANVRDRKDVQGRRCGDMRFGLLRSEWEAWKRK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448771	Streptococcus phage Javan481, complete genome	30395-30428	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448973	Streptococcus phage Javan522, complete genome	37021-37054	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448779	Streptococcus phage Javan497, complete genome	35272-35305	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448969	Streptococcus phage Javan514, complete genome	29119-29152	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	NC_004585	Streptococcus prophage 315.2, complete genome	36333-36366	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448966	Streptococcus phage Javan508, complete genome	36188-36221	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448970	Streptococcus phage Javan516, complete genome	41767-41800	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448972	Streptococcus phage Javan520, complete genome	31054-31087	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448795	Streptococcus phage Javan527, complete genome	41788-41821	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448968	Streptococcus phage Javan512, complete genome	35380-35413	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448959	Streptococcus phage Javan488, complete genome	36878-36911	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448774	Streptococcus phage Javan487, complete genome	29233-29266	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448772	Streptococcus phage Javan483, complete genome	36431-36464	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448778	Streptococcus phage Javan493, complete genome	36664-36697	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448773	Streptococcus phage Javan485, complete genome	32005-32038	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448797	Streptococcus phage Javan531, complete genome	35380-35413	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448949	Streptococcus phage Javan460, complete genome	37677-37710	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448957	Streptococcus phage Javan484, complete genome	40845-40878	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448975	Streptococcus phage Javan526, complete genome	37446-37479	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	NC_004589	Streptococcus prophage 315.6, complete genome	35477-35510	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448782	Streptococcus phage Javan501, complete genome	39804-39837	0	1.0
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448858	Streptococcus phage Javan166, complete genome	41883-41916	2	0.941
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448860	Streptococcus phage Javan172, complete genome	34800-34833	2	0.941
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	NC_009018	Streptococcus phage phi3396, complete genome	33995-34028	2	0.941
NZ_LR595857_3	3.1\|1451392\|34\|NZ_LR595857\|CRT	1451392-1451425	34	MK448958	Streptococcus phage Javan486, complete genome	35788-35821	2	0.941
NZ_LR595857_3	3.2\|1451458\|33\|NZ_LR595857\|CRT	1451458-1451490	33	MK448681	Streptococcus phage Javan141, complete genome	15472-15504	2	0.939
NZ_LR595857_3	3.3\|1451523\|34\|NZ_LR595857\|CRT	1451523-1451556	34	MK448675	Streptococcus phage Javan129, complete genome	9410-9443	2	0.941
NZ_LR595857_3	3.3\|1451523\|34\|NZ_LR595857\|CRT	1451523-1451556	34	MK449010	Streptococcus phage Javan90, complete genome	7627-7660	2	0.941
NZ_LR595857_3	3.3\|1451523\|34\|NZ_LR595857\|CRT	1451523-1451556	34	MK448833	Streptococcus phage Javan87, complete genome	7627-7660	2	0.941
NZ_LR595857_3	3.7\|1451458\|32\|NZ_LR595857\|PILER-CR	1451458-1451489	32	MK448681	Streptococcus phage Javan141, complete genome	15472-15503	2	0.938
NZ_LR595857_3	3.8\|1451523\|33\|NZ_LR595857\|PILER-CR	1451523-1451555	33	MK448675	Streptococcus phage Javan129, complete genome	9411-9443	2	0.939
NZ_LR595857_3	3.8\|1451523\|33\|NZ_LR595857\|PILER-CR	1451523-1451555	33	MK449010	Streptococcus phage Javan90, complete genome	7628-7660	2	0.939
NZ_LR595857_3	3.8\|1451523\|33\|NZ_LR595857\|PILER-CR	1451523-1451555	33	MK448833	Streptococcus phage Javan87, complete genome	7628-7660	2	0.939
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448852	Streptococcus phage Javan140, complete genome	36773-36805	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448973	Streptococcus phage Javan522, complete genome	37781-37813	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	NC_004585	Streptococcus prophage 315.2, complete genome	37093-37125	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448966	Streptococcus phage Javan508, complete genome	36948-36980	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448972	Streptococcus phage Javan520, complete genome	31814-31846	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448795	Streptococcus phage Javan527, complete genome	42548-42580	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448791	Streptococcus phage Javan517, complete genome	36606-36638	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448763	Streptococcus phage Javan451, complete genome	31661-31693	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448959	Streptococcus phage Javan488, complete genome	37638-37670	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	NC_004587	Streptococcus prophage 315.4, complete genome	36182-36214	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	NC_003157	Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome	37452-37484	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448772	Streptococcus phage Javan483, complete genome	37191-37223	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448778	Streptococcus phage Javan493, complete genome	37424-37456	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448686	Streptococcus phage Javan157, complete genome	37764-37796	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448977	Streptococcus phage Javan530, complete genome	36087-36119	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	NC_009819	Streptococcus phage P9, complete genome	36313-36345	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448949	Streptococcus phage Javan460, complete genome	38434-38466	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448951	Streptococcus phage Javan470, complete genome	36289-36321	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448777	Streptococcus phage Javan491, complete genome	31534-31566	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448845	Streptococcus phage Javan118, complete genome	33365-33397	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448788	Streptococcus phage Javan511, complete genome	36087-36119	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448954	Streptococcus phage Javan476, complete genome	36214-36246	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448950	Streptococcus phage Javan464, complete genome	36808-36840	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448975	Streptococcus phage Javan526, complete genome	38206-38238	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448678	Streptococcus phage Javan135, complete genome	36254-36286	3	0.909
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448782	Streptococcus phage Javan501, complete genome	40565-40597	3	0.909
NZ_LR595857_3	3.3\|1451523\|34\|NZ_LR595857\|CRT	1451523-1451556	34	MK448672	Streptococcus phage Javan117, complete genome	4850-4883	3	0.912
NZ_LR595857_3	3.3\|1451523\|34\|NZ_LR595857\|CRT	1451523-1451556	34	MK448673	Streptococcus phage Javan119, complete genome	8218-8251	3	0.912
NZ_LR595857_3	3.8\|1451523\|33\|NZ_LR595857\|PILER-CR	1451523-1451555	33	MK448672	Streptococcus phage Javan117, complete genome	4851-4883	3	0.909
NZ_LR595857_3	3.8\|1451523\|33\|NZ_LR595857\|PILER-CR	1451523-1451555	33	MK448673	Streptococcus phage Javan119, complete genome	8219-8251	3	0.909
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448771	Streptococcus phage Javan481, complete genome	30395-30432	4	0.895
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448973	Streptococcus phage Javan522, complete genome	37021-37058	4	0.895
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448779	Streptococcus phage Javan497, complete genome	35272-35309	4	0.895
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448969	Streptococcus phage Javan514, complete genome	29119-29156	4	0.895
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	NC_004585	Streptococcus prophage 315.2, complete genome	36333-36370	4	0.895
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448966	Streptococcus phage Javan508, complete genome	36188-36225	4	0.895
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448970	Streptococcus phage Javan516, complete genome	41767-41804	4	0.895
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448972	Streptococcus phage Javan520, complete genome	31054-31091	4	0.895
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448795	Streptococcus phage Javan527, complete genome	41788-41825	4	0.895
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448968	Streptococcus phage Javan512, complete genome	35380-35417	4	0.895
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448959	Streptococcus phage Javan488, complete genome	36878-36915	4	0.895
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448774	Streptococcus phage Javan487, complete genome	29233-29270	4	0.895
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448772	Streptococcus phage Javan483, complete genome	36431-36468	4	0.895
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448778	Streptococcus phage Javan493, complete genome	36664-36701	4	0.895
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448773	Streptococcus phage Javan485, complete genome	32005-32042	4	0.895
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448797	Streptococcus phage Javan531, complete genome	35380-35417	4	0.895
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448949	Streptococcus phage Javan460, complete genome	37677-37714	4	0.895
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448957	Streptococcus phage Javan484, complete genome	40845-40882	4	0.895
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448975	Streptococcus phage Javan526, complete genome	37446-37483	4	0.895
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	NC_004589	Streptococcus prophage 315.6, complete genome	35477-35514	4	0.895
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448782	Streptococcus phage Javan501, complete genome	39804-39841	4	0.895
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448675	Streptococcus phage Javan129, complete genome	39674-39706	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448860	Streptococcus phage Javan172, complete genome	35576-35608	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448865	Streptococcus phage Javan182, complete genome	29347-29379	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448690	Streptococcus phage Javan169, complete genome	39307-39339	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448864	Streptococcus phage Javan180, complete genome	27244-27276	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448850	Streptococcus phage Javan132, complete genome	38774-38806	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448946	Streptococcus phage Javan456, complete genome	40893-40925	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448767	Streptococcus phage Javan467, complete genome	31580-31612	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448771	Streptococcus phage Javan481, complete genome	31154-31186	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448784	Streptococcus phage Javan505, complete genome	37673-37705	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448942	Streptococcus phage Javan448, complete genome	22597-22629	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	NC_004586	Streptococcus pyogenes phage 315.3, complete genome	31685-31717	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448779	Streptococcus phage Javan497, complete genome	36029-36061	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448969	Streptococcus phage Javan514, complete genome	29879-29911	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448947	Streptococcus phage Javan458, complete genome	37673-37705	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448792	Streptococcus phage Javan521, complete genome	36291-36323	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448965	Streptococcus phage Javan506, complete genome	38042-38074	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448964	Streptococcus phage Javan502, complete genome	31454-31486	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448943	Streptococcus phage Javan450, complete genome	31580-31612	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448944	Streptococcus phage Javan452, complete genome	39575-39607	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448968	Streptococcus phage Javan512, complete genome	36137-36169	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	NC_004584	Streptococcus prophage 315.1, complete genome	35884-35916	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448786	Streptococcus phage Javan509, complete genome	31580-31612	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448774	Streptococcus phage Javan487, complete genome	29993-30025	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448773	Streptococcus phage Javan485, complete genome	32765-32797	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448797	Streptococcus phage Javan531, complete genome	36137-36169	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448958	Streptococcus phage Javan486, complete genome	36547-36579	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448770	Streptococcus phage Javan477, complete genome	36291-36323	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448689	Streptococcus phage Javan163, complete genome	37673-37705	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448978	Streptococcus phage Javan532, complete genome	35778-35810	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448933	Streptococcus phage Javan420, complete genome	41607-41639	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448974	Streptococcus phage Javan524, complete genome	37673-37705	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448785	Streptococcus phage Javan507, complete genome	35779-35811	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448957	Streptococcus phage Javan484, complete genome	41605-41637	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448764	Streptococcus phage Javan457, complete genome	29303-29335	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448789	Streptococcus phage Javan513, complete genome	37672-37704	5	0.848
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	NC_004589	Streptococcus prophage 315.6, complete genome	36234-36266	5	0.848
NZ_LR595857_3	3.6\|1451523\|38\|NZ_LR595857\|CRISPRCasFinder	1451523-1451560	38	MK449010	Streptococcus phage Javan90, complete genome	7623-7660	5	0.868
NZ_LR595857_3	3.6\|1451523\|38\|NZ_LR595857\|CRISPRCasFinder	1451523-1451560	38	MK448833	Streptococcus phage Javan87, complete genome	7623-7660	5	0.868
NZ_LR595857_3	3.6\|1451523\|38\|NZ_LR595857\|CRISPRCasFinder	1451523-1451560	38	MK448675	Streptococcus phage Javan129, complete genome	9406-9443	5	0.868
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448676	Streptococcus phage Javan131, complete genome	41650-41682	6	0.818
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448858	Streptococcus phage Javan166, complete genome	41883-41920	6	0.842
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448860	Streptococcus phage Javan172, complete genome	34800-34837	6	0.842
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	NC_009018	Streptococcus phage phi3396, complete genome	33995-34032	6	0.842
NZ_LR595857_3	3.4\|1451392\|38\|NZ_LR595857\|CRISPRCasFinder	1451392-1451429	38	MK448958	Streptococcus phage Javan486, complete genome	35788-35825	6	0.842
NZ_LR595857_3	3.5\|1451458\|37\|NZ_LR595857\|CRISPRCasFinder	1451458-1451494	37	MK448681	Streptococcus phage Javan141, complete genome	15472-15508	6	0.838
NZ_LR595857_3	3.6\|1451523\|38\|NZ_LR595857\|CRISPRCasFinder	1451523-1451560	38	MK448672	Streptococcus phage Javan117, complete genome	4846-4883	6	0.842
NZ_LR595857_3	3.6\|1451523\|38\|NZ_LR595857\|CRISPRCasFinder	1451523-1451560	38	MK448673	Streptococcus phage Javan119, complete genome	8214-8251	6	0.842
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448855	Streptococcus phage Javan150, complete genome	32442-32474	7	0.788
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448894	Streptococcus phage Javan272, complete genome	29325-29357	7	0.788
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448725	Streptococcus phage Javan275, complete genome	28651-28683	7	0.788
NZ_LR595857_2	2.1\|882710\|33\|NZ_LR595857\|CRISPRCasFinder	882710-882742	33	MK448723	Streptococcus phage Javan271, complete genome	38323-38355	8	0.758

1. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

2. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

3. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448779 (Streptococcus phage Javan497, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

4. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

5. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to NC_004585 (Streptococcus prophage 315.2, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

6. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448966 (Streptococcus phage Javan508, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

7. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448970 (Streptococcus phage Javan516, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

8. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

9. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

10. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448968 (Streptococcus phage Javan512, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

11. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448959 (Streptococcus phage Javan488, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

12. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

13. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448772 (Streptococcus phage Javan483, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

14. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

15. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

16. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448797 (Streptococcus phage Javan531, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

17. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448949 (Streptococcus phage Javan460, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

18. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448957 (Streptococcus phage Javan484, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

19. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448975 (Streptococcus phage Javan526, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

20. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to NC_004589 (Streptococcus prophage 315.6, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

21. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448782 (Streptococcus phage Javan501, complete genome) position: , mismatch: 0, identity: 1.0

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaaga	Protospacer
**********************************

22. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448858 (Streptococcus phage Javan166, complete genome) position: , mismatch: 2, identity: 0.941

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacgctggttgacagtactaaaga	Protospacer
************** ****.**************

23. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448860 (Streptococcus phage Javan172, complete genome) position: , mismatch: 2, identity: 0.941

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgacgtgtttacggtggtcgacagtactaaaga	Protospacer
****.** **************************

24. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to NC_009018 (Streptococcus phage phi3396, complete genome) position: , mismatch: 2, identity: 0.941

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgatgtctttacgctggttgacagtactaaaga	Protospacer
************** ****.**************

25. spacer 3.1|1451392|34|NZ_LR595857|CRT matches to MK448958 (Streptococcus phage Javan486, complete genome) position: , mismatch: 2, identity: 0.941

atgatgtctttacggtggtcgacagtactaaaga	CRISPR spacer
atgacgtgtttacggtggtcgacagtactaaaga	Protospacer
****.** **************************

26. spacer 3.2|1451458|33|NZ_LR595857|CRT matches to MK448681 (Streptococcus phage Javan141, complete genome) position: , mismatch: 2, identity: 0.939

gcgtacataaacgaagcgacattagcgaataaa	CRISPR spacer
gcgtatataaacgaagcgacattagcaaataaa	Protospacer
*****.********************.******

27. spacer 3.3|1451523|34|NZ_LR595857|CRT matches to MK448675 (Streptococcus phage Javan129, complete genome) position: , mismatch: 2, identity: 0.941

cgtgtatgtctgtgtgacctgcaccaaggtaggt	CRISPR spacer
catgtatgtctgtgtgacctgcgccaaggtaggt	Protospacer
*.********************.***********

28. spacer 3.3|1451523|34|NZ_LR595857|CRT matches to MK449010 (Streptococcus phage Javan90, complete genome) position: , mismatch: 2, identity: 0.941

cgtgtatgtctgtgtgacctgcaccaaggtaggt	CRISPR spacer
catgtatgtctgtgtgacctgcgccaaggtaggt	Protospacer
*.********************.***********

29. spacer 3.3|1451523|34|NZ_LR595857|CRT matches to MK448833 (Streptococcus phage Javan87, complete genome) position: , mismatch: 2, identity: 0.941

cgtgtatgtctgtgtgacctgcaccaaggtaggt	CRISPR spacer
catgtatgtctgtgtgacctgcgccaaggtaggt	Protospacer
*.********************.***********

30. spacer 3.7|1451458|32|NZ_LR595857|PILER-CR matches to MK448681 (Streptococcus phage Javan141, complete genome) position: , mismatch: 2, identity: 0.938

gcgtacataaacgaagcgacattagcgaataa	CRISPR spacer
gcgtatataaacgaagcgacattagcaaataa	Protospacer
*****.********************.*****

31. spacer 3.8|1451523|33|NZ_LR595857|PILER-CR matches to MK448675 (Streptococcus phage Javan129, complete genome) position: , mismatch: 2, identity: 0.939

cgtgtatgtctgtgtgacctgcaccaaggtagg	CRISPR spacer
catgtatgtctgtgtgacctgcgccaaggtagg	Protospacer
*.********************.**********

32. spacer 3.8|1451523|33|NZ_LR595857|PILER-CR matches to MK449010 (Streptococcus phage Javan90, complete genome) position: , mismatch: 2, identity: 0.939

cgtgtatgtctgtgtgacctgcaccaaggtagg	CRISPR spacer
catgtatgtctgtgtgacctgcgccaaggtagg	Protospacer
*.********************.**********

33. spacer 3.8|1451523|33|NZ_LR595857|PILER-CR matches to MK448833 (Streptococcus phage Javan87, complete genome) position: , mismatch: 2, identity: 0.939

cgtgtatgtctgtgtgacctgcaccaaggtagg	CRISPR spacer
catgtatgtctgtgtgacctgcgccaaggtagg	Protospacer
*.********************.**********

34. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448852 (Streptococcus phage Javan140, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

35. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

36. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to NC_004585 (Streptococcus prophage 315.2, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

37. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448966 (Streptococcus phage Javan508, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

38. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

39. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

40. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448791 (Streptococcus phage Javan517, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tgattgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

41. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tgattgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

42. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448959 (Streptococcus phage Javan488, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

43. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to NC_004587 (Streptococcus prophage 315.4, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tgattgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

44. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to NC_003157 (Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tgattgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

45. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448772 (Streptococcus phage Javan483, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

46. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

47. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448686 (Streptococcus phage Javan157, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

48. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448977 (Streptococcus phage Javan530, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tgattgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

49. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to NC_009819 (Streptococcus phage P9, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tgattgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

50. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448949 (Streptococcus phage Javan460, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

51. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448951 (Streptococcus phage Javan470, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

52. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448777 (Streptococcus phage Javan491, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

53. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tgattgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

54. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448788 (Streptococcus phage Javan511, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tgattgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

55. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tgattgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

56. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

57. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448975 (Streptococcus phage Javan526, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

58. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448678 (Streptococcus phage Javan135, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

59. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448782 (Streptococcus phage Javan501, complete genome) position: , mismatch: 3, identity: 0.909

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttagata	Protospacer
 . ******************************

60. spacer 3.3|1451523|34|NZ_LR595857|CRT matches to MK448672 (Streptococcus phage Javan117, complete genome) position: , mismatch: 3, identity: 0.912

cgtgtatgtctgtgtgacctgcaccaaggtaggt	CRISPR spacer
catgtatgtctgtgtgacctgcgccaaggtacgt	Protospacer
*.********************.******** **

61. spacer 3.3|1451523|34|NZ_LR595857|CRT matches to MK448673 (Streptococcus phage Javan119, complete genome) position: , mismatch: 3, identity: 0.912

cgtgtatgtctgtgtgacctgcaccaaggtaggt	CRISPR spacer
catgtatgtctgtttgacctgcaccaagataggt	Protospacer
*.*********** **************.*****

62. spacer 3.8|1451523|33|NZ_LR595857|PILER-CR matches to MK448672 (Streptococcus phage Javan117, complete genome) position: , mismatch: 3, identity: 0.909

cgtgtatgtctgtgtgacctgcaccaaggtagg	CRISPR spacer
catgtatgtctgtgtgacctgcgccaaggtacg	Protospacer
*.********************.******** *

63. spacer 3.8|1451523|33|NZ_LR595857|PILER-CR matches to MK448673 (Streptococcus phage Javan119, complete genome) position: , mismatch: 3, identity: 0.909

cgtgtatgtctgtgtgacctgcaccaaggtagg	CRISPR spacer
catgtatgtctgtttgacctgcaccaagatagg	Protospacer
*.*********** **************.****

64. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

65. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

66. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448779 (Streptococcus phage Javan497, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

67. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

68. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to NC_004585 (Streptococcus prophage 315.2, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

69. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448966 (Streptococcus phage Javan508, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

70. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448970 (Streptococcus phage Javan516, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

71. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

72. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

73. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448968 (Streptococcus phage Javan512, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

74. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448959 (Streptococcus phage Javan488, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

75. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

76. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448772 (Streptococcus phage Javan483, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

77. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

78. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

79. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448797 (Streptococcus phage Javan531, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

80. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448949 (Streptococcus phage Javan460, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

81. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448957 (Streptococcus phage Javan484, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

82. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448975 (Streptococcus phage Javan526, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

83. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to NC_004589 (Streptococcus prophage 315.6, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

84. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448782 (Streptococcus phage Javan501, complete genome) position: , mismatch: 4, identity: 0.895

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacggtggtcgacagtactaaagaggaa	Protospacer
**********************************.

85. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448675 (Streptococcus phage Javan129, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttggatg	Protospacer
 . *************************.***.

86. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448860 (Streptococcus phage Javan172, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttggatg	Protospacer
 . *************************.***.

87. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448865 (Streptococcus phage Javan182, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tgattgctcttatcttttatccgtttttaggtg	Protospacer
 . ***************************.*.

88. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448690 (Streptococcus phage Javan169, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttggatg	Protospacer
 . *************************.***.

89. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448864 (Streptococcus phage Javan180, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tgattgctcttatcttttatccgtttttaggtg	Protospacer
 . ***************************.*.

90. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448850 (Streptococcus phage Javan132, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttatccgtttttggatg	Protospacer
 . *************************.***.

91. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448946 (Streptococcus phage Javan456, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
ttgttgctctgatcttttatccatttttagata	Protospacer
   ******* ***********.**********

92. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448767 (Streptococcus phage Javan467, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatctttttcccgtttttagata	Protospacer
 . *************** .*************

93. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
ttgttgctctgatcttttatccatttttagata	Protospacer
   ******* ***********.**********

94. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448784 (Streptococcus phage Javan505, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttacccgtttgtagata	Protospacer
 . ****************.****** ******

95. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448942 (Streptococcus phage Javan448, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
ttgttgctctgatcttttatccatttttagata	Protospacer
   ******* ***********.**********

96. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to NC_004586 (Streptococcus pyogenes phage 315.3, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatctttttcccgtttttagata	Protospacer
 . *************** .*************

97. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448779 (Streptococcus phage Javan497, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
ttgttgctctgatcttttatccatttttagata	Protospacer
   ******* ***********.**********

98. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
ttgttgctctgatcttttatccatttttagata	Protospacer
   ******* ***********.**********

99. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448947 (Streptococcus phage Javan458, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttacccgtttgtagata	Protospacer
 . ****************.****** ******

100. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448792 (Streptococcus phage Javan521, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
ttgttgctctgatcttttatccatttttagata	Protospacer
   ******* ***********.**********

101. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448965 (Streptococcus phage Javan506, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttacccgtttgtagata	Protospacer
 . ****************.****** ******

102. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
ttgttgctctgatcttttatccatttttagata	Protospacer
   ******* ***********.**********

103. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448943 (Streptococcus phage Javan450, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatctttttcccgtttttagata	Protospacer
 . *************** .*************

104. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
ttgttgctctgatcttttatccatttttagata	Protospacer
   ******* ***********.**********

105. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448968 (Streptococcus phage Javan512, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
ttgttgctctgatcttttatccatttttagata	Protospacer
   ******* ***********.**********

106. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to NC_004584 (Streptococcus prophage 315.1, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
ttgttgctctgatcttttatccatttttagata	Protospacer
   ******* ***********.**********

107. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448786 (Streptococcus phage Javan509, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatctttttcccgtttttagata	Protospacer
 . *************** .*************

108. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
ttgttgctctgatcttttatccatttttagata	Protospacer
   ******* ***********.**********

109. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
ttgttgctctgatcttttatccatttttagata	Protospacer
   ******* ***********.**********

110. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448797 (Streptococcus phage Javan531, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
ttgttgctctgatcttttatccatttttagata	Protospacer
   ******* ***********.**********

111. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448958 (Streptococcus phage Javan486, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
ttgttgctctgatcttttatccatttttagata	Protospacer
   ******* ***********.**********

112. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448770 (Streptococcus phage Javan477, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
ttgttgctctgatcttttatccatttttagata	Protospacer
   ******* ***********.**********

113. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448689 (Streptococcus phage Javan163, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttacccgtttgtagata	Protospacer
 . ****************.****** ******

114. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448978 (Streptococcus phage Javan532, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
ttgttgctctgatcttttatccatttttagata	Protospacer
   ******* ***********.**********

115. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448933 (Streptococcus phage Javan420, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tgattgctcttatcttttatccgtttttaaaaa	Protospacer
 . **************************.* *

116. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448974 (Streptococcus phage Javan524, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttacccgtttgtagata	Protospacer
 . ****************.****** ******

117. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448785 (Streptococcus phage Javan507, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
ttgttgctctgatcttttatccatttttagata	Protospacer
   ******* ***********.**********

118. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448957 (Streptococcus phage Javan484, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
ttgttgctctgatcttttatccatttttagata	Protospacer
   ******* ***********.**********

119. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448764 (Streptococcus phage Javan457, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
ttgttgctctgatcttttatccatttttagata	Protospacer
   ******* ***********.**********

120. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448789 (Streptococcus phage Javan513, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcttttacccgtttgtagata	Protospacer
 . ****************.****** ******

121. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to NC_004589 (Streptococcus prophage 315.6, complete genome) position: , mismatch: 5, identity: 0.848

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
ttgttgctctgatcttttatccatttttagata	Protospacer
   ******* ***********.**********

122. spacer 3.6|1451523|38|NZ_LR595857|CRISPRCasFinder matches to MK449010 (Streptococcus phage Javan90, complete genome) position: , mismatch: 5, identity: 0.868

cgtgtatgtctgtgtgacctgcaccaaggtaggtattt	CRISPR spacer
catgtatgtctgtgtgacctgcgccaaggtaggtaaaa	Protospacer
*.********************.************

123. spacer 3.6|1451523|38|NZ_LR595857|CRISPRCasFinder matches to MK448833 (Streptococcus phage Javan87, complete genome) position: , mismatch: 5, identity: 0.868

cgtgtatgtctgtgtgacctgcaccaaggtaggtattt	CRISPR spacer
catgtatgtctgtgtgacctgcgccaaggtaggtaaaa	Protospacer
*.********************.************

124. spacer 3.6|1451523|38|NZ_LR595857|CRISPRCasFinder matches to MK448675 (Streptococcus phage Javan129, complete genome) position: , mismatch: 5, identity: 0.868

cgtgtatgtctgtgtgacctgcaccaaggtaggtattt	CRISPR spacer
catgtatgtctgtgtgacctgcgccaaggtaggtgaat	Protospacer
*.********************.***********.  *

125. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448676 (Streptococcus phage Javan131, complete genome) position: , mismatch: 6, identity: 0.818

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tgattgctcttatcttttatccgttttttgagg	Protospacer
 . ************************* ** .

126. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448858 (Streptococcus phage Javan166, complete genome) position: , mismatch: 6, identity: 0.842

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacgctggttgacagtactaaagaggaa	Protospacer
************** ****.**************.

127. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448860 (Streptococcus phage Javan172, complete genome) position: , mismatch: 6, identity: 0.842

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgacgtgtttacggtggtcgacagtactaaagagaaa	Protospacer
****.** **************************.

128. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to NC_009018 (Streptococcus phage phi3396, complete genome) position: , mismatch: 6, identity: 0.842

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgatgtctttacgctggttgacagtactaaagaggaa	Protospacer
************** ****.**************.

129. spacer 3.4|1451392|38|NZ_LR595857|CRISPRCasFinder matches to MK448958 (Streptococcus phage Javan486, complete genome) position: , mismatch: 6, identity: 0.842

atgatgtctttacggtggtcgacagtactaaagaattt	CRISPR spacer
atgacgtgtttacggtggtcgacagtactaaagaggaa	Protospacer
****.** **************************.

130. spacer 3.5|1451458|37|NZ_LR595857|CRISPRCasFinder matches to MK448681 (Streptococcus phage Javan141, complete genome) position: , mismatch: 6, identity: 0.838

gcgtacataaacgaagcgacattagcgaataaaattt	CRISPR spacer
gcgtatataaacgaagcgacattagcaaataaagaag	Protospacer
*****.********************.******.

131. spacer 3.6|1451523|38|NZ_LR595857|CRISPRCasFinder matches to MK448672 (Streptococcus phage Javan117, complete genome) position: , mismatch: 6, identity: 0.842

cgtgtatgtctgtgtgacctgcaccaaggtaggtattt	CRISPR spacer
catgtatgtctgtgtgacctgcgccaaggtacgtaaaa	Protospacer
*.********************.******** ***

132. spacer 3.6|1451523|38|NZ_LR595857|CRISPRCasFinder matches to MK448673 (Streptococcus phage Javan119, complete genome) position: , mismatch: 6, identity: 0.842

cgtgtatgtctgtgtgacctgcaccaaggtaggtattt	CRISPR spacer
catgtatgtctgtttgacctgcaccaagataggtgaat	Protospacer
*.*********** **************.*****.  *

133. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448855 (Streptococcus phage Javan150, complete genome) position: , mismatch: 7, identity: 0.788

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tgatcgctcttatcttttatccgttttttgagg	Protospacer
 . *.*********************** ** .

134. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448894 (Streptococcus phage Javan272, complete genome) position: , mismatch: 7, identity: 0.788

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcgtttatccttttttaaaca	Protospacer
 . *********** ******* ******.*.*

135. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448725 (Streptococcus phage Javan275, complete genome) position: , mismatch: 7, identity: 0.788

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tggttgctcttatcgtttatccttttttaaaca	Protospacer
 . *********** ******* ******.*.*

136. spacer 2.1|882710|33|NZ_LR595857|CRISPRCasFinder matches to MK448723 (Streptococcus phage Javan271, complete genome) position: , mismatch: 8, identity: 0.758

aacttgctcttatcttttatccgtttttagata	CRISPR spacer
tgattgctcttatcgtttatccattttttaaca	Protospacer
 . *********** *******.***** .*.*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

37452 : 50417

Streptococcus_phage(25.0%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_143936352.1\|37452_38874_-\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	2.2e-240	88.1
WP_012766410.1\|39085_39796_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3FUQ7	Synechococcus_phage	5.7e-40	39.7
WP_143936353.1\|40004_43730_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	6.4e-34	25.8
WP_046177524.1\|43848_45300_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-58	34.0
WP_003062570.1\|45452_46481_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	3.7e-64	43.6
WP_003056410.1\|46473_47028_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.8e-23	34.1
WP_015057184.1\|47134_47647_+	VanZ family protein	NA	NA	NA	NA
WP_046177523.1\|47665_49210_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	2.4e-75	48.1
WP_003055557.1\|49289_50417_-	SH3 domain-containing protein	F8HGP2	Streptococcus_phage	9.1e-08	28.6

DBSCAN-SWA_2

422030 : 433447

Streptococcus_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003058688.1\|422030_422795_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	9.5e-17	28.3
WP_171841621.1\|422800_423505_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	3.0e-17	28.4
WP_003059946.1\|423549_424212_+	CBS domain-containing protein	M1NSC5	Streptococcus_phage	1.2e-60	57.4
WP_003058667.1\|424298_424934_+	dTMP kinase	M1PSC7	Streptococcus_phage	6.8e-69	65.9
WP_003058651.1\|424949_425822_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	5.9e-55	41.4
WP_046176980.1\|425818_426619_+	signal peptidase II	NA	NA	NA	NA
WP_003058686.1\|426611_426935_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	7.0e-30	64.2
WP_046176979.1\|426939_427803_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	7.7e-116	76.0
WP_003062448.1\|427829_428222_+	hypothetical protein	NA	NA	NA	NA
WP_046176978.1\|428268_428898_-	copper homeostasis protein CutC	NA	NA	NA	NA
WP_003058674.1\|429014_430106_+	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	5.3e-130	63.1
WP_003061315.1\|430131_430683_+	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	3.0e-49	53.6
WP_003058665.1\|430743_431241_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.4e-40	52.9
WP_022554296.1\|431237_431594_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	6.3e-40	65.0
WP_046176977.1\|431644_432067_-	VOC family protein	NA	NA	NA	NA
WP_046176976.1\|432068_432458_-	VOC family protein	NA	NA	NA	NA
WP_046176975.1\|432619_433447_-	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	2.9e-128	79.1

DBSCAN-SWA_3

527599 : 535079

Bacillus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003057217.1\|527599_528394_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.2e-36	40.4
WP_003049952.1\|528652_529363_+	response regulator transcription factor	W8CYM9	Bacillus_phage	5.7e-40	39.4
WP_003060939.1\|529355_530708_+	cell wall metabolism sensor histidine kinase VicK	W8CYF6	Bacillus_phage	3.6e-35	34.6
WP_115256786.1\|530711_531521_+	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	8.7e-37	37.5
WP_046177434.1\|531601_532477_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_143936365.1\|533161_534178_-\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	2.3e-34	32.5
WP_003057240.1\|534386_535079_+	ribonuclease III	A0A167RGU4	Powai_lake_megavirus	2.5e-24	31.6

DBSCAN-SWA_4

581967 : 589632

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014612128.1\|581967_582309_+	helix-turn-helix transcriptional regulator	A0A0S2MVM8	Bacillus_phage	7.4e-06	44.1
WP_065355268.1\|582484_583066_+	hypothetical protein	NA	NA	NA	NA
WP_115256792.1\|583314_583920_+	hypothetical protein	NA	NA	NA	NA
WP_046177516.1\|584869_585553_+	helix-turn-helix transcriptional regulator	A0A1S5SAF1	Streptococcus_phage	3.2e-56	48.1
WP_046177515.1\|585554_586970_+	Y-family DNA polymerase	Q6DMX4	Streptococcus_phage	4.2e-204	74.7
WP_046177514.1\|586966_587344_+	hypothetical protein	A0A1B0RXA8	Streptococcus_phage	6.7e-24	50.8
WP_046177513.1\|587321_587624_+	hypothetical protein	A0A1B0RX98	Streptococcus_phage	3.3e-21	51.5
WP_143936432.1\|588006_589632_-	N-6 DNA methylase	A0A1V0SF44	Hokovirus	8.2e-10	23.0

DBSCAN-SWA_5

886705 : 950763

Streptococcus_phage(25.0%)

transposase,tRNA,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003058431.1\|886705_886936_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_003058441.1\|886935_887232_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_015017090.1\|887421_888591_+	DUF2974 domain-containing protein	NA	NA	NA	NA
WP_046177076.1\|888701_889721_+	YeiH family putative sulfate export transporter	NA	NA	NA	NA
WP_003058453.1\|889927_890353_+	PTS mannose transporter subunit IIA	NA	NA	NA	NA
WP_003058434.1\|890372_890864_+	PTS system mannose/fructose/N-acetylgalactosamine-transporter subunit IIB	NA	NA	NA	NA
WP_046177075.1\|890880_891690_+	PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC	NA	NA	NA	NA
WP_046177074.1\|891686_892514_+	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_003062586.1\|892659_894309_+	sensor histidine kinase	NA	NA	NA	NA
WP_003061999.1\|894312_895107_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_046177073.1\|895093_896143_+	extracellular solute-binding protein	NA	NA	NA	NA
WP_003058426.1\|896238_896745_+	YkgJ family cysteine cluster protein	NA	NA	NA	NA
WP_046177071.1\|897330_897897_+	sugar O-acetyltransferase	NA	NA	NA	NA
WP_015017084.1\|898832_899540_+	noncanonical pyrimidine nucleotidase, YjjG family	NA	NA	NA	NA
WP_046177070.1\|899617_900994_+	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_046177069.1\|901049_901199_+	HAD hydrolase family protein	NA	NA	NA	NA
WP_046177068.1\|901328_903113_+	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_015057631.1\|903165_903582_-	pyruvate oxidase	NA	NA	NA	NA
WP_046177067.1\|903609_903789_-	hypothetical protein	NA	NA	NA	NA
WP_080937728.1\|903752_904592_-	pyruvate oxidase	NA	NA	NA	NA
WP_003054310.1\|905073_905676_+	nitroreductase family protein	NA	NA	NA	NA
WP_046177065.1\|905853_907263_+	dipeptidase PepV	NA	NA	NA	NA
WP_143936375.1\|907402_908884_+\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.6e-254	91.3
WP_003053708.1\|908893_910270_-\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE	NA	NA	NA	NA
WP_003060751.1\|910411_911095_+	ribose-5-phosphate isomerase RpiA	NA	NA	NA	NA
WP_046177542.1\|911173_912385_+	phosphopentomutase	NA	NA	NA	NA
WP_022554718.1\|912403_912844_+	arsenate reductase (glutaredoxin)	A0A2H4J8T1	uncultured_Caudovirales_phage	1.3e-34	54.5
WP_003053715.1\|912827_913637_+	purine-nucleoside phosphorylase	Q5YBA4	Grouper_iridovirus	8.7e-53	42.2
WP_003053699.1\|914188_914902_+	purine-nucleoside phosphorylase	NA	NA	NA	NA
WP_003053701.1\|914894_915665_+	hypothetical protein	NA	NA	NA	NA
WP_003053703.1\|915746_916664_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_012767079.1\|916888_917437_+	hypothetical protein	NA	NA	NA	NA
WP_003053723.1\|917648_918341_+	orotidine-5'-phosphate decarboxylase	NA	NA	NA	NA
WP_003060988.1\|918401_919031_+	orotate phosphoribosyltransferase	Q58MW1	Prochlorococcus_phage	1.4e-05	34.1
WP_046177541.1\|919071_919818_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_115256712.1\|919887_921235_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.9e-60	49.6
WP_003060129.1\|921414_922869_+	amidase	NA	NA	NA	NA
WP_046177536.1\|922987_923851_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_046177537.1\|923879_924530_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_002994022.1\|924662_925316_+	uracil-DNA glycosylase	A0A0N9QWR4	Chrysochromulina_ericina_virus	1.2e-33	39.0
WP_046177538.1\|925447_926719_+	dihydroorotase	NA	NA	NA	NA
WP_015017071.1\|926778_927420_-	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_046177540.1\|927554_929504_+	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	5.6e-122	41.8
WP_003057638.1\|929570_930389_+	hypothetical protein	NA	NA	NA	NA
WP_046177539.1\|930585_933045_+	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	1.6e-94	32.6
WP_015057616.1\|934726_935749_+	branched-chain amino acid aminotransferase	NA	NA	NA	NA
WP_003057631.1\|935812_936043_+	DUF2969 domain-containing protein	NA	NA	NA	NA
WP_046177575.1\|936431_937637_+	30S ribosomal protein S1	NA	NA	NA	NA
WP_143936377.1\|937942_939427_+\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.0e-253	91.3
WP_046177558.1\|939495_940116_-	DUF3862 domain-containing protein	NA	NA	NA	NA
WP_003053567.1\|940856_941471_+	TVP38/TMEM64 family protein	M1Q152	Streptococcus_phage	8.6e-53	55.4
WP_046177557.1\|941606_942395_-	hypothetical protein	NA	NA	NA	NA
WP_003053563.1\|942404_943103_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.7e-20	27.7
WP_003053565.1\|943102_943474_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_046177556.1\|943660_946771_+	DNA polymerase III subunit alpha	A0A2L1IZ23	Streptomyces_phage	4.9e-120	29.2
WP_003053569.1\|946850_947864_+	6-phosphofructokinase	NA	NA	NA	NA
WP_003053551.1\|947926_949429_+	pyruvate kinase	NA	NA	NA	NA
WP_115256893.1\|949629_950763_+\|transposase	ISAs1-like element IS1548 family transposase	NA	NA	NA	NA

DBSCAN-SWA_6

1330307 : 1341415

Streptococcus_phage(84.62%)

transposase,integrase

attL 1327835:1327850|attR 1339429:1339444

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1327835:1327850	attL	NA	NA	NA	NA
WP_046177190.1\|1330307_1330703_-	hypothetical protein	K4JTJ9	Streptococcus_phage	3.5e-31	52.4
WP_046177191.1\|1330720_1331047_-	hypothetical protein	NA	NA	NA	NA
WP_053042316.1\|1331039_1331468_-	hypothetical protein	NA	NA	NA	NA
WP_046177192.1\|1331506_1331794_-	hypothetical protein	NA	NA	NA	NA
WP_115256952.1\|1332263_1333407_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	6.4e-17	27.2
WP_000273649.1\|1333728_1333911_-	hypothetical protein	NA	NA	NA	NA
WP_053042318.1\|1334160_1335045_-	ATP-binding protein	A0A1X9I6C4	Streptococcus_phage	3.8e-70	49.1
WP_046177304.1\|1335056_1335878_-	phage replisome organizer N-terminal domain-containing protein	A3F622	Streptococcus_phage	1.5e-52	50.4
WP_046177303.1\|1335864_1336074_-	hypothetical protein	A0A1X9I5W7	Streptococcus_phage	3.1e-07	40.3
WP_165742490.1\|1336078_1336237_-	hypothetical protein	A0A1X9I5Z1	Streptococcus_phage	1.6e-19	88.5
WP_000190301.1\|1336247_1336514_-	hypothetical protein	A0A1X9I6M4	Streptococcus_phage	6.1e-40	96.6
WP_046177302.1\|1336523_1336727_-	hypothetical protein	A0A1X9I725	Streptococcus_phage	1.6e-16	70.1
WP_046177301.1\|1336729_1336981_-	hypothetical protein	NA	NA	NA	NA
WP_046177300.1\|1337152_1337341_-	hypothetical protein	A0A1X9I5U7	Streptococcus_phage	6.1e-26	96.8
WP_053042317.1\|1337514_1338039_+	helix-turn-helix transcriptional regulator	Q9AZN3	Lactococcus_phage	2.6e-10	51.5
WP_115256955.1\|1338115_1339279_+\|integrase	site-specific integrase	A0A1X9I6A9	Streptococcus_phage	7.0e-197	88.9
WP_003050115.1\|1339427_1340735_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	1.3e-239	96.6
1339429:1339444	attR	NA	NA	NA	NA
WP_012766765.1\|1340959_1341415_+	DUF1694 domain-containing protein	W6LLD2	Streptococcus_phage	1.1e-17	39.3

DBSCAN-SWA_7

1667241 : 1753288

109

Streptococcus_phage(56.92%)

portal,tRNA,head,terminase,protease,integrase,capsid,tail

attL 1710458:1710473|attR 1753904:1753919

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046176790.1\|1667241_1669281_-\|tRNA	glycine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_003061240.1\|1669523_1670441_-\|tRNA	glycine--tRNA ligase subunit alpha	NA	NA	NA	NA
WP_003059177.1\|1671152_1671686_-	isoprenylcysteine carboxyl methyltransferase family protein	NA	NA	NA	NA
WP_046176886.1\|1671822_1672662_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	7.1e-50	38.5
WP_003054133.1\|1672768_1673920_-	N-acetylglucosamine-6-phosphate deacetylase	NA	NA	NA	NA
WP_046159559.1\|1674036_1675668_-	Na/Pi cotransporter family protein	NA	NA	NA	NA
WP_046176791.1\|1675907_1676597_+	hypothetical protein	NA	NA	NA	NA
WP_003054136.1\|1676778_1677621_-	DegV family protein	A0A1X9I5J4	Streptococcus_phage	3.4e-92	61.9
WP_003054132.1\|1677910_1678468_+	TetR/AcrR family transcriptional regulator	A0A1X9I6A2	Streptococcus_phage	9.0e-17	47.5
WP_003054134.1\|1678602_1679430_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_003054137.1\|1679431_1680049_-	trimeric intracellular cation channel family protein	NA	NA	NA	NA
WP_046176792.1\|1680242_1681220_-	tagatose-bisphosphate aldolase	NA	NA	NA	NA
WP_003061423.1\|1681200_1682154_-	tagatose-6-phosphate kinase	NA	NA	NA	NA
WP_003052284.1\|1682163_1682679_-	galactose-6-phosphate isomerase subunit LacB	NA	NA	NA	NA
WP_015058003.1\|1682693_1683119_-	galactose-6-phosphate isomerase subunit LacA	NA	NA	NA	NA
WP_012767470.1\|1683376_1684828_-	PTS galactitol transporter subunit IIC	NA	NA	NA	NA
WP_003052292.1\|1684853_1685159_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_003062658.1\|1685151_1685625_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_046176793.1\|1685858_1686629_+	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_003057059.1\|1686828_1687032_-	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_046176794.1\|1687045_1689277_-	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	2.2e-114	37.7
WP_022555074.1\|1689276_1689711_-	CopY/TcrY family copper transport repressor	NA	NA	NA	NA
WP_003060486.1\|1690933_1691563_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_046176795.1\|1691571_1692297_-	class B sortase	NA	NA	NA	NA
WP_111679036.1\|1692320_1693343_-	QVPTGV class sortase B protein-sorting domain-containing protein	NA	NA	NA	NA
WP_037590054.1\|1693374_1693848_-	signal peptidase I	NA	NA	NA	NA
WP_046176796.1\|1693905_1695411_-	Cys-Gln thioester bond-forming surface protein	NA	NA	NA	NA
WP_046176797.1\|1695882_1697049_+	YSIRK-targeted surface antigen transcriptional regulator	NA	NA	NA	NA
WP_046176798.1\|1698214_1699201_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_002994317.1\|1699333_1699684_-	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_012767488.1\|1699889_1702787_-	translation initiation factor IF-2	E3T4N3	Cafeteria_roenbergensis_virus	2.0e-19	25.2
WP_003052320.1\|1702806_1703109_-	YlxQ-related RNA-binding protein	NA	NA	NA	NA
WP_003057040.1\|1703101_1703398_-	YlxR family protein	NA	NA	NA	NA
WP_003057051.1\|1703413_1704571_-	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_044022604.1\|1704713_1705208_-	ribosome maturation factor RimP	NA	NA	NA	NA
WP_046176799.1\|1705676_1705856_-	hypothetical protein	A3F673	Streptococcus_phage	1.7e-17	71.2
WP_015984836.1\|1706032_1706341_+	hypothetical protein	A3F672	Streptococcus_phage	2.5e-53	100.0
WP_046176800.1\|1706374_1706854_+	hypothetical protein	A3F671	Streptococcus_phage	5.6e-84	95.6
WP_046176801.1\|1706850_1707036_+	helix-turn-helix domain-containing protein	A3F670	Streptococcus_phage	1.2e-23	96.7
WP_046176802.1\|1707051_1707342_+	hypothetical protein	A3F669	Streptococcus_phage	1.8e-48	90.6
WP_053042312.1\|1707662_1708868_-	Fic family protein	Q9AZ49	Lactococcus_phage	7.6e-61	36.4
WP_046176804.1\|1709284_1710481_-	streptodornase Sda1	Q938J4	Temperate_phage	4.5e-191	81.2
1710458:1710473	attL	NA	NA	NA	NA
WP_002988802.1\|1710591_1710777_-	hypothetical protein	Q938J5	Temperate_phage	9.5e-24	93.4
WP_002988799.1\|1710773_1711073_-	hypothetical protein	Q938J6	Temperate_phage	3.5e-36	82.3
WP_046176806.1\|1711083_1711695_-	DUF1366 domain-containing protein	Q938J7	Temperate_phage	2.1e-75	85.7
WP_046176807.1\|1711697_1712129_-	DUF1617 family protein	Q938J8	Temperate_phage	4.5e-56	79.7
WP_046176808.1\|1712142_1714056_-	gp58-like family protein	A3F659	Streptococcus_phage	2.4e-162	63.5
WP_046176809.1\|1714066_1714702_-	hypothetical protein	A0A097PBF7	Streptococcus_pyogenes_phage	2.1e-86	75.8
WP_046176810.1\|1714701_1715553_-	collagen-like protein	A3F657	Streptococcus_phage	2.5e-18	74.2
WP_143936415.1\|1715552_1717700_-\|tail	phage tail protein	Q938K1	Temperate_phage	0.0e+00	90.9
WP_046176812.1\|1717696_1718404_-\|tail	phage tail family protein	Q938K2	Temperate_phage	3.4e-93	71.9
WP_046176813.1\|1718403_1722342_-\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	4.3e-254	50.0
WP_046176815.1\|1722551_1722872_-	hypothetical protein	J7KK85	Streptococcus_phage	7.4e-40	75.5
WP_046176816.1\|1722979_1723525_-\|tail	major tail protein	J7KKC8	Streptococcus_phage	7.6e-77	78.1
WP_003055350.1\|1723540_1723966_-	hypothetical protein	J7KBZ9	Streptococcus_phage	5.9e-69	85.8
WP_003055321.1\|1723962_1724340_-	HK97 gp10 family phage protein	J7KDM3	Streptococcus_phage	1.5e-47	76.0
WP_046176817.1\|1724336_1724684_-\|head	phage head closure protein	J7KJ42	Streptococcus_phage	1.5e-49	85.5
WP_046176818.1\|1724680_1724983_-\|head,tail	phage head-tail connector protein	J7KC36	Streptococcus_phage	3.5e-39	83.7
WP_046176819.1\|1725127_1726315_-\|capsid	phage major capsid protein	J7KJ82	Streptococcus_phage	5.4e-160	74.9
WP_046176820.1\|1726339_1727005_-\|protease	Clp protease ClpP	M1Q115	Streptococcus_phage	4.6e-92	77.7
WP_003055341.1\|1726982_1728203_-\|portal	phage portal protein	J7KDU3	Streptococcus_phage	1.3e-188	82.9
WP_003055359.1\|1728236_1728503_-	hypothetical protein	Q938K9	Temperate_phage	3.7e-29	81.4
WP_023080038.1\|1728499_1728667_-	hypothetical protein	J7KK43	Streptococcus_phage	3.3e-07	56.2
WP_046176888.1\|1728663_1730418_-	amino acid transporter	J7KKD1	Streptococcus_phage	0.0e+00	96.1
WP_046176821.1\|1730421_1730652_-	hypothetical protein	NA	NA	NA	NA
WP_023080043.1\|1730654_1731122_-\|terminase	phage terminase small subunit P27 family	J7KC46	Streptococcus_phage	1.1e-81	98.1
WP_046176822.1\|1731292_1731631_-	HNH endonuclease	J7KH36	Streptococcus_phage	8.6e-55	90.7
WP_001132273.1\|1731731_1731917_+	type II toxin-antitoxin system HicA family toxin	F0PIL1	Enterococcus_phage	8.7e-09	58.1
WP_046176823.1\|1731968_1732346_+	type II toxin-antitoxin system HicB family antitoxin	I3NLB2	Bifidobacterium_phage	7.4e-15	43.1
WP_053042313.1\|1732411_1733284_-	hypothetical protein	NA	NA	NA	NA
WP_003052405.1\|1733919_1734357_-	DUF1492 domain-containing protein	A0A097PBF1	Streptococcus_pyogenes_phage	3.6e-77	100.0
WP_158001801.1\|1734719_1734893_-	hypothetical protein	NA	NA	NA	NA
WP_172453886.1\|1734885_1735056_-	hypothetical protein	NA	NA	NA	NA
WP_053042314.1\|1735052_1735604_-	DUF1642 domain-containing protein	A0A097PAV5	Streptococcus_pyogenes_phage	7.6e-08	34.0
WP_046176824.1\|1735616_1736291_-	site-specific DNA-methyltransferase	A3F629	Streptococcus_phage	3.9e-131	97.8
WP_046176825.1\|1736287_1737187_-	N-6 DNA methylase	A0A0M3LQ47	Mannheimia_phage	2.1e-79	54.2
WP_046176826.1\|1737183_1737552_-	HNH endonuclease	Q7Y4J8	Streptococcus_phage	4.5e-41	68.8
WP_046176891.1\|1737541_1737811_-	hypothetical protein	A7J287	Streptococcus_phage	9.3e-20	59.6
WP_046176827.1\|1737810_1737987_-	hypothetical protein	NA	NA	NA	NA
WP_046176828.1\|1738165_1738447_-	DUF1599 domain-containing protein	J7KDH9	Streptococcus_phage	7.7e-33	74.2
WP_046176829.1\|1738443_1738692_-	hypothetical protein	Q938M4	Temperate_phage	8.5e-36	92.6
WP_046176830.1\|1738688_1739045_-	hypothetical protein	A0A1P8VVP9	Streptococcus_phage	5.0e-53	85.6
WP_046176831.1\|1739041_1739482_-	RusA family crossover junction endodeoxyribonuclease	A0A097PAS0	Streptococcus_pyogenes_phage	5.4e-73	90.4
WP_046176832.1\|1739481_1739688_-	hypothetical protein	Q938M6	Temperate_phage	1.7e-21	74.2
WP_046176833.1\|1739699_1740119_-	single-stranded DNA-binding protein	Q938M7	Temperate_phage	3.3e-64	89.2
WP_046176834.1\|1740111_1740786_-	ERF family protein	A0A097PBE8	Streptococcus_pyogenes_phage	3.2e-109	90.2
WP_046176835.1\|1740786_1741269_-	siphovirus Gp157 family protein	A0A1P8VVS5	Streptococcus_phage	2.7e-54	73.1
WP_046176837.1\|1741430_1741637_-	hypothetical protein	NA	NA	NA	NA
WP_000166038.1\|1741645_1741786_-	hypothetical protein	NA	NA	NA	NA
WP_046176838.1\|1741782_1742016_-	hypothetical protein	Q938N1	Temperate_phage	9.2e-24	71.4
WP_046176839.1\|1741996_1742821_-	DnaD domain protein	L0P704	Lactobacillus_phage	1.4e-34	58.8
WP_046176840.1\|1742936_1743380_-	hypothetical protein	G4KNN0	Staphylococcus_phage	1.0e-10	32.0
WP_027970310.1\|1743561_1743729_-	ribbon-helix-helix domain-containing protein	NA	NA	NA	NA
WP_172601565.1\|1743854_1743995_-	hypothetical protein	A0A1P8VVR9	Streptococcus_phage	4.0e-14	82.2
WP_046176841.1\|1743991_1744267_-	DNA-binding phage protein	A7J272	Streptococcus_phage	1.6e-46	97.8
WP_046176892.1\|1744323_1744509_-	helix-turn-helix transcriptional regulator	J7KH19	Streptococcus_phage	1.8e-22	83.6
WP_046176842.1\|1744655_1744886_+	hypothetical protein	NA	NA	NA	NA
WP_046176843.1\|1744995_1745718_-	phage antirepressor KilAC domain-containing protein	M1Q1T4	Streptococcus_phage	4.0e-102	77.4
WP_046176844.1\|1745750_1745939_-	helix-turn-helix transcriptional regulator	A0A0B5A7F0	Streptococcus_phage	1.1e-14	66.7
WP_046176845.1\|1746032_1746764_+	hypothetical protein	NA	NA	NA	NA
WP_046176846.1\|1746767_1747010_-	hypothetical protein	A0A1X9I5R9	Streptococcus_phage	1.5e-05	87.1
WP_115256797.1\|1747044_1747203_-	hypothetical protein	A0A097PAP2	Streptococcus_pyogenes_phage	3.4e-22	94.2
WP_046176847.1\|1747560_1748325_+	helix-turn-helix transcriptional regulator	E8ZDN4	Streptococcus_phage	5.8e-83	63.4
WP_046176848.1\|1748334_1748640_+	membrane protein	NA	NA	NA	NA
WP_046176849.1\|1748756_1749836_+\|integrase	site-specific integrase	A7J266	Streptococcus_phage	4.9e-176	87.2
WP_046176850.1\|1750034_1750670_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_003052472.1\|1750669_1751461_-	phosphotransferase family protein	NA	NA	NA	NA
WP_046176851.1\|1751525_1752560_-	ABC transporter permease	NA	NA	NA	NA
WP_003057032.1\|1752562_1753288_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.7e-26	30.6
1753904:1753919	attR	NA	NA	NA	NA

DBSCAN-SWA_8

2069482 : 2080982

Streptococcus_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046177147.1\|2069482_2072038_-	DNA mismatch repair protein MutS	A0A1V0SGG8	Hokovirus	2.7e-39	25.5
WP_003062220.1\|2072024_2072378_-	YlbF family regulator	NA	NA	NA	NA
WP_003055516.1\|2072374_2072812_-	arginine repressor	NA	NA	NA	NA
WP_046177148.1\|2073100_2074792_+\|tRNA	arginine--tRNA ligase	A0A2I2L3K1	Orpheovirus	6.4e-74	32.4
WP_014612639.1\|2074861_2076259_-	ABC-F family ATP-binding cassette domain-containing protein	A0A1B0RXA0	Streptococcus_phage	6.5e-48	28.3
WP_003055540.1\|2076435_2077350_-	YitT family protein	M1Q1P6	Streptococcus_phage	2.0e-53	40.1
WP_046177149.1\|2077379_2078279_-	YitT family protein	M1Q1P6	Streptococcus_phage	1.8e-46	35.2
WP_003055524.1\|2078299_2079241_-	YitT family protein	NA	NA	NA	NA
WP_003055520.1\|2079233_2080982_-\|tRNA	aspartate--tRNA ligase	A0A1V0SJ84	Klosneuvirus	4.5e-14	26.1

Anti-CRISPR protein detection

Acr_ID: NZ_LR595857.1|WP_000384270.1|273123_273450_+|replication-initiator-protein-A

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_LR595857.1|WP_000384270.1|273123_273450_+|replication-initiator-protein-A

273123_273450_+

108 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|63	0.9444444444444444	1	1.0

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LR595857

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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