CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LR699012	Anaerostipes hadrus isolate MGYG-HGUT-02528 chromosome 1	4 crisprs	cas14k,csa3,cas14j,DEDDh,cas3HD,cas3,cas6,cas8b2,cas7,cas5,cas4,cas1,cas2	0	1	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LR699012_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LR699012_1

694888-694985

Orphan

Consensus_repeat	Method
GGTTTTTCTTTCTGTTTTTGATCTTTTTTTAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LR699012_1

>merge|NZ_LR699012|1|694888-694985|CRISPRCasFinder
GGTTTTTCTTTCTGTTTTTGATCTTTTTTTAGACACAACCAATGGTGCAAATTCAAAGTTCTGAGGGGTTTTTCTTCCTGTTTTTGATCTTTTTTTAG

>NZ_LR699012|1|1|694888-694985|CRISPRCasFinder
GGTTTTTCTTTCTGTTTTTGATCTTTTTTTAG	ACACAACCAATGGTGCAAATTCAAAGTTCTGAGG
GGTTTTTCTTCCTGTTTTTGATCTTTTTTTAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LR699012.1\|WP_077325702.1\|700392_701040_-\|CatB-related-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100040
NZ_LR699012.1\|WP_077325704.1\|701053_702409_-\|oligosaccharide-repeat-unit-polymerase	unknown	unknown	gnl\|CDD\|275163
NZ_LR699012.1\|WP_077325708.1\|703331_704402_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340831
NZ_LR699012.1\|WP_077325680.1\|691532_691865_-\|transposase	unknown	unknown	gnl\|CDD\|376980
NZ_LR699012.1\|WP_040343850.1\|690936_691338_-\|IS66-family-insertion-sequence-hypothetical-protein	unknown	unknown	gnl\|CDD\|366690
NZ_LR699012.1\|WP_077325692.1\|696516_696984_-\|VanZ-family-protein	unknown	unknown	gnl\|CDD\|377417
NZ_LR699012.1\|WP_077325690.1\|695567_696485_-\|nucleotidyltransferase	unknown	unknown	gnl\|CDD\|133024
NZ_LR699012.1\|WP_077325675.1\|688852_690502_-\|IS66-family-transposase	unknown	unknown	gnl\|CDD\|376980
NZ_LR699012.1\|WP_077325671.1\|684310_686500_-\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223528
NZ_LR699012.1\|WP_077325698.1\|699437_700208_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368570
NZ_LR699012.1\|WP_077325684.1\|692438_693104_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LR699012.1\|WP_077325686.1\|693175_693871_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LR699012.1\|WP_077325682.1\|691910_692249_-\|transposase	unknown	unknown	gnl\|CDD\|376980
NZ_LR699012.1\|WP_077325706.1\|702428_703316_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133039
NZ_LR699012.1\|WP_077325696.1\|698027_699425_-\|oligosaccharide-flippase-family-protein	unknown	unknown	gnl\|CDD\|240533
NZ_LR699012.1\|WP_077325678.1\|690577_690943_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551
NZ_LR699012.1\|WP_153811601.1\|688644_688821_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LR699012.1\|WP_077325700.1\|700204_700396_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LR699012.1\|WP_077325673.1\|686542_687586_-\|Stealth-CR1-domain-containing-protein	unknown	unknown	gnl\|CDD\|371500
NZ_LR699012.1\|WP_077325694.1\|696976_698002_-\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|226122

Protein	Function_ID	Function_description	E-value
NZ_LR699012.1\|WP_077325702.1\|700392_701040_-\|CatB-related-O-acetyltransferase	gnl\|CDD\|100040	cd03349, LbH_XAT, Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. Members of this class of enzymes include Enterococcus faecium streptogramin A acetyltransferase and Pseudomonas aeruginosa chloramphenicol acetyltransferase. They contain repeated copies of a six-residue hexapeptide repeat sequence motif (X-[STAV]-X-[LIV]-[GAED]-X) and adopt a left-handed parallel beta helix (LbH) structure. The active enzyme is a trimer with CoA and substrate binding sites at the interface of two separate LbH subunits. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients.	1.69527e-49
NZ_LR699012.1\|WP_077325680.1\|691532_691865_-\|transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	1.32528e-21
NZ_LR699012.1\|WP_077325704.1\|701053_702409_-\|oligosaccharide-repeat-unit-polymerase	gnl\|CDD\|275163	TIGR04370, hypothetical_protein, oligosaccharide repeat unit polymerase. Members of this subfamily of highly hydrophobic proteins, with few highly conserved residues, all may act to polymerize the oligosaccharide repeat units of surface polysaccharides, including O-antigen in Gram-negative bacteria such as Leptospira (assign gene symbol wzy) and capsular polysaccharide in Gram-positive bacteria such as Streptococcus. O-antigen biosynthesis enzymes produce a repeat unit, usually an oligosaccharide, which itself is polymerized. O-antigen polymerase, usually designated Wzy. This family bears homology to the O-antigen ligase WaaL, but known examples of WaaL fall outside the bounds defined here. This model is much broader than pfam14296. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	5.96118e-08
NZ_LR699012.1\|WP_077325692.1\|696516_696984_-\|VanZ-family-protein	gnl\|CDD\|377417	pfam04892, VanZ, VanZ like family. This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases.	4.01631e-12
NZ_LR699012.1\|WP_077325708.1\|703331_704402_-\|glycosyltransferase	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	2.57544e-45
NZ_LR699012.1\|WP_077325675.1\|688852_690502_-\|IS66-family-transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	7.80787e-88
NZ_LR699012.1\|WP_077325671.1\|684310_686500_-\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|223528	COG0451, WcaG, Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	1.43756e-11
NZ_LR699012.1\|WP_040343850.1\|690936_691338_-\|IS66-family-insertion-sequence-hypothetical-protein	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	2.76927e-05
NZ_LR699012.1\|WP_077325690.1\|695567_696485_-\|nucleotidyltransferase	gnl\|CDD\|133024	cd04181, NTP_transferase, NTP_transferases catalyze the transfer of nucleotides onto phosphosugars. Nucleotidyltransferases transfer nucleotides onto phosphosugars. The enzyme family includes Alpha-D-Glucose-1-Phosphate Cytidylyltransferase, Mannose-1-phosphate guanyltransferase, and Glucose-1-phosphate thymidylyltransferase. The products are activated sugars that are precursors for synthesis of lipopolysaccharide, glycolipids and polysaccharides.	9.49298e-13
NZ_LR699012.1\|WP_077325706.1\|702428_703316_-\|glycosyltransferase	gnl\|CDD\|133039	cd04196, GT_2_like_d, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	8.42017e-61
NZ_LR699012.1\|WP_077325682.1\|691910_692249_-\|transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	3.74029e-15
NZ_LR699012.1\|WP_077325678.1\|690577_690943_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	1.01786e-47
NZ_LR699012.1\|WP_077325696.1\|698027_699425_-\|oligosaccharide-flippase-family-protein	gnl\|CDD\|240533	cd13128, MATE_Wzx_like, Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	1.93229e-15
NZ_LR699012.1\|WP_077325698.1\|699437_700208_-\|hypothetical-protein	gnl\|CDD\|368570	pfam05704, Caps_synth, Capsular polysaccharide synthesis protein. This family consists of several capsular polysaccharide proteins. Capsular polysaccharide (CPS) is a major virulence factor in Streptococcus pneumoniae.	1.40013e-65
NZ_LR699012.1\|WP_077325673.1\|686542_687586_-\|Stealth-CR1-domain-containing-protein	gnl\|CDD\|371500	pfam11380, Stealth_CR2, Stealth protein CR2, conserved region 2. Stealth_CR2 is the second of several highly conserved regions on stealth proteins in metazoa and bacteria. There are up to four CR regions on all member proteins. CR2 carries a well-conserved NDD sequence-motif. The domain is found in tandem with CR1, CR3 and CR4 on both potential metazoan hosts and pathogenic eubacterial species that are capsular polysaccharide phosphotransferases. The CR domains appear on eukaryotic proteins such as GNPTAB, N-acetylglucosamine-1-phosphotransferase subunits alpha/beta. Horizontal gene-transfer seems to have occurred between host and bacteria of these sequence-regions in order for the bacteria to evade detection by the host innate immune system.	1.55787e-62
NZ_LR699012.1\|WP_077325694.1\|696976_698002_-\|acyltransferase-family-protein	gnl\|CDD\|226122	COG3594, NolL, Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism].	6.15728e-17

>NZ_LR699012.1|WP_077325686.1|693175_693871_-|hypothetical-protein
MKKALILKSIENYLNYHPPAEQLFKELYEIGELYLIGGVLREFLDAGDIKNLRDIDIVINTKEIDKFNEICLKYQAQKNSFDGYKMMCTDLVVDVWRIEQTWAYRENVIECQENDYLRNLTQTVFYNMDSIVYDIKKDMWYDDVYKKTKENNVLDIVLEENPYIDLNILRGMILQSTYDMKYSSKIKNIVRDRYQQENNYEKLLYDIEIKRYKREILSLDDIKNQLYRIVL
>NZ_LR699012.1|WP_077325684.1|692438_693104_-|hypothetical-protein
MEIIKNTWFVGISTGIISGIVVFFFTKWIMDRKERVEYFKRVSNANQNIIETLKTYIAENGLPDIEVLVALNMSTARAFNVDVNEMYSISDYCEELIREIMRDVYVSNEKKKEYIDMLVKYKEKIKTINYVEQYQTLKMNDEKNRKQINADLPKIVAMLGMATGSFLGVNDWSKGIFHIINDDLMEWVPTFIYAIIVNFVLLYVGFEIVPKVRKNLRFRRH
>NZ_LR699012.1|WP_077325682.1|691910_692249_-|transposase
MQNDIFQSYRCEHIFLDGIKPGYYFMADGYQGYNLLKDGKRCCCYAHIRRYLLEAIPKGHEKDYTDPAVQGVLYCDKLFEYERRYREKGFSPEQREKQRLKDEKPVIEAFLS
>NZ_LR699012.1|WP_077325680.1|691532_691865_-|transposase
MIYIRNRKDSLMTYLEDGRCSLSNNLSENAIRPITVGRKNWLFCDSVDGANASAICFTMIEMAKAYDLNVYKYLNFLLEKRPNARTAQKELEKLAPWNEEVQKMFARKMK
>NZ_LR699012.1|WP_040343850.1|690936_691338_-|IS66-family-insertion-sequence-hypothetical-protein
MRAKRRTEQEQYEIIMECRQSGLSDHQWCLEHDINPGTFYNWVRRFRKQACEFPAPAGKDRFQAIHQEVVKMEIIPDQSTDLYGPSSTEDIAEITKPVATMELQIGQAVLRISNQTDPRLLEQTLKLIGAFSC
>NZ_LR699012.1|WP_077325678.1|690577_690943_-|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MLGDISVVDDIYIVCGYTDMRKQIDGLYSIVKDQFHMDPEQRALYLFCGRRCDRIKALLYENDGFVLLYKRLTASEGRYRWPRNKNEVQPITWRQFDWLMSGLEIEQPKAIRPRKPENEKE
>NZ_LR699012.1|WP_077325675.1|688852_690502_-|IS66-family-transposase
MSSGRNDIRLIELKDTISQLNQTIRVQTEMIKDLRKAIEEHHASDEKKDQIISNLQAEISYLKAKLFGASSEKRRKEDLPGQMSLFDELMEEEPAKEIEPEYIEIKAHERKRKKKPDLNEQFRDIPVRQEFVDTLTEEQKTCSICGTKMVEIGHELIRSEVIFTPAKLERVEYIATTYGCPKCKETEEPQFVKDNGIPALLRGSYVSPSLAAHVICQKFMNAMPLYRQEKDWEQLGATITRASMARWIIHCSKTYFQPMYEYFEKQLKKRKFLMMDETRLQVLKEEGRRAQTQSFIWVVRSGEDGLPKIVLYHYTETRAGKHAVGFLDGIKPGYYFMADGYHGYNLLKDGKRCCCYAHIRRYLLEAIPKGHEKDYTDPAVQGVLYCDKLFEYERRYREKGFSPEQRKKRRLKDEKPVIEAFLSWLDAQTPVKGSRLDKAVIYIRNRKDSLMTYLEDGRCSLSNNLSENAIRPITVGRKNWLFCDSVDGANASAICFTMIEMAKAYDLNVYKYLNFLLEKRPNARTAQKELEKLAPWNEEVQKMFARKMK
>NZ_LR699012.1|WP_153811601.1|688644_688821_+|hypothetical-protein
MDFEIQSVSDLFSILFKMEGQTDLEIATSKDLANLSEDSDRPALSLSSTDQTWVSALS
>NZ_LR699012.1|WP_077325673.1|686542_687586_-|Stealth-CR1-domain-containing-protein
MRKVDKNTQDIDFVITWVDGNDLEWKREKAARMGHTDMDISVNADDRKERYRDWNNLRYWFRGMEKYAPWVRKVHFVTWGHIPQWLNTKHPKLNIVCHEDFIPQKFLPTFNSHTIEWNFHRIPGLTEQFVYFNDDMFLLKPVYMEDFFKDEKPIDMLALQPDVANVDDPTMPYIYLNNTMLLAKYFDKRSNIKKQPWAYFHIGYPPMYFLYNVLELAFQRFTGFYTVHGPSPLKKSTYQKLWELEPELLSDVCSHPFRHREDVSQYVLREYQKLSGEFVPENVQKICGYYDAEQTNDRLVRSILRQKKKIICINDSNHEIDFEKVKKEINQAFEQVFSEKSSFENSI
>NZ_LR699012.1|WP_077325671.1|684310_686500_-|NAD(P)-dependent-oxidoreductase
MNILLVGGSCSLINSMILKLRKEGHRIFLLTGDKYRHNKYERVFEKYEFSYDCENLNDILESVNADVTILMGAFDTNYRWDGEERETVLFISHLVNILVAYSVKNKKRLIFLSSDEIYNGNYTEDIKEEEPFSGVGIRADALSQAEDICDNFRINRSLDIITLRLDHLYNIPKERKDVNNICADMCLNCMCDGHIKAKTDHTFSLLYENDAVEYIYQFIKTSNHKYSLYNLSSNDVVSEVKLAAMIQKAMEIESNIVAFSDSNGRCVLSGNRFEREFGVHAFGNLEKNIKDMVSYMKKHESVFLKGDDLKLSWWKMFYEKWKWLIRTLFPFFENLVCFVPFFMMNNRTVGSEYFANLDPFLLYVLLFAIVYGQQQATFSAILAVAGYMFRQMYTRNSFEVLIDYNTYVWIAQLFILGLVVGYMRDQIRIMRLESQELEEHLHRQIVNIQDINESNVRVKEVMEQQLIDHKDSIGKIYSITAGLEQRMPDEVIFYAVEMLGKLMKTKDVALYNVVSKDYARIFSASSQKARSLGNSIRYREMTDIYDALKEQKVYINKKMDEQYPLMARGIYEGEEVQMIVMMWGLSWEKMTLGQANFLTVVSYLIQNAVLRAQRYMQALEEKRYSQNSRILEPEAFESLVQAYMKAKLKNLVECVLIKVDVQNSEYQKTDEQMSGYMRDSDYMGMLPDGNLYVLLTNTTREGAVIVQDRFEKNGYKTEYVEMMSVCHRE
>NZ_LR699012.1|WP_077325690.1|695567_696485_-|nucleotidyltransferase
MNTTLIIMAAGIGSRFGEGIKQLAQMGPNGEIIMDYSIHDAKEAGFNKVVFIIRKDIFKEFEEIIGNRIKEQIDVEYVFQEVDDLPEGFEVPEGRTKPWGTGQAVLCCKDVVKEPFVIINADDYYGKEAFVKLHDFLVSGEDLGREFTMGMGGFILKNTLSDNGTVTRGVSVVDEDGLLSQVHETTGIEMGEDGQIKCDSEEVQKWISPEDKVSMNMWAGYPEFLDFLAEDFKDFLANVEEGDLKSEYLLPNIVDKLLKEERANVKVLETQDRWFGVTYKEDKETVQEAFRKLISDGVYAEMLWE
>NZ_LR699012.1|WP_077325692.1|696516_696984_-|VanZ-family-protein
MYKSLGGLKEKYQNHMLEIVWKIMLGIYIMILFYLTLAGRKQVDPLINVFGGWLPFKRSNQTWNIDALYNIFLLTPLTFFLGKSFPHITKKNLFKKMILISFGISFFIEINQLIFAIGTFQVSDLVYNTISGVIGGVIYKMSYKITSENLSSQGP
>NZ_LR699012.1|WP_077325694.1|696976_698002_-|acyltransferase-family-protein
MKKVQREDWADFAKGIGIILVRFGHQKIFGKKLIYLIYAFHMPLFFMISGYFYKNDKGAIKQIKHKAYSILMPYFSYEMAKWIMVVLKGFIINKKLDFHMNFLLGLFLNIPESQYCNPIWFFSCLFSAEVVFIIINKIIFRYCTAEKQSRNVLICTLIISAVAYVWYLHIGVRLLWNLDLALIMLPFLGVGSWIKINGILKKICDLKYMIIYAMLLVAVCIVNASFGQTNIDYAMRNYNEWFSCILVGVIGTLFILTICIKIKENKLLRFIGKNSGLYYLMIGTVTKAWGKVYQCIIGTSKNEYIYFFFTLTLALITLVPICYILNRYFAFFIGKKRVQNV
>NZ_LR699012.1|WP_077325696.1|698027_699425_-|oligosaccharide-flippase-family-protein
MKKGLINVMMANIICLIINLLTNFLVPKYVSIESYGMIKTYALYLTYAGFFSMGYNDGMYLKYGGKKLEDINKEGLANNFVNYIVLMLIMFVIVLLGGIIFDDFIIACFAFGMLSYNILGYLKSLYQATGEFKAYGNALNIEKFAVFAITILLIFLFHSDNYKLYIVTQVGIGIIVAIYLFIKLENKLHFVRMGHIRKSEYKENISSGIILMLGNFSSGIFTGLDRWFVKLLLSAINFAMYSFAVSVESIINVFISPITISMYNYFCKNPPINSVKRIKRLSLMWGFIVIAAAFPAKWILENYLQKYIFANSIIFTLFASEIFYLVVKGIYVNIYKSEKKQNLYLKQMIAMIVIGSVLNGIFVAIFKNMESIAVATLITAIIWMYLCEIPSKELRFSIKENFAIGIIIISFLFCGYEMEAIIGCIVYCIVLFLVCLIAFNDEVKYAFEFGKGGIQLIKDKISDNK
>NZ_LR699012.1|WP_077325698.1|699437_700208_-|hypothetical-protein
MKIDILESQMKQLKKESKILKQSYIWIFWWQGVSEDTPDIVKQVIKSVEKYKGNHEIVILNKENISKYIQIPQFTYEKLKSGIISIPHFADIIRTKLLYEYGGIWMDATLYMTDTFSNDIYNNYFYTINHTQRADYHVCKGKWSTFFLASAKGNPFFLYLTDMQLKYWKYENKAICYLIIDCFIALAYENNEIVKNMIDSVPINHVNVFEMQKESNSLYTREKYVNLCKNGYLHKLTYKRKNDNSEKTIYNYILNN
>NZ_LR699012.1|WP_077325700.1|700204_700396_-|hypothetical-protein
MKKIYGIMPKKLVNSFEIVHYFGLKFGILDFFDSLIFKHRGRIGKKFEHYRYEKVKQYLKKNT
>NZ_LR699012.1|WP_077325702.1|700392_701040_-|CatB-related-O-acetyltransferase
MLNRILFFFQKIKIRRDWKKNNKKNKTTLGIITNRAYINFVKNGGIVVGKNTYGRLNVNYTGAKEEKLIIGANCSIAGSSNFLLGGEHDYSKITMYPYSYRIFGMKNDVKTKGPIIVEDEVWIGDDSWIKSGVHIGKGAIIATGAVVTKDVPPYAIVGGVPAQIIKYRFSEEIINKIIDVNLSELNIPKEAIGLLDTSLTEKNIDLILERIRQYI
>NZ_LR699012.1|WP_077325704.1|701053_702409_-|oligosaccharide-repeat-unit-polymerase
MLYLLFIVTIILFLSTYYICNRDILAPSVLCCIMYIISIMFAVLNIKNWGIDYQTKTFGIMVTAIIAFIIPSLLFYIRPSMAKSKRNDNTSLTAIVCDNKILIICLIIDILITAYYFKEVNRISILGGNNMGVAGMFSYYRFYTANNADAETLSTLANQMLKLGRSFGFVALFIFMYNNQIDKNMKRDKLLIPFIILAALQNIIGGGRGYILWLVCFGFTTAYIVNMKKYSWKKSLAFKYIKIGAIALIVVFIAFYLLKYLVRVGNTVNSILDYIGYYAGGSVQNFNLYIQDPPASSKTIWGQESFMGIYSTLEKFKLVDLSGVYLTNSNLEFRQSNGVAIGNVYGAIRRYYNDFGIGGVIVLQMIASTFFNTFYYCLKKASNNHSKFIYLFYAYLFYHVYELPIDDTFFKNFISFNMITTFIVLYIVYYIFTNVKITTRLRIICRIKNRT
>NZ_LR699012.1|WP_077325706.1|702428_703316_-|glycosyltransferase
MISLVMATYNGEKYLYEQLDSIRCQTMPPDEVIICDDCSKDSTVNMIQKYIDKYQLKHWNVYENEKNKGYSKNFSDALKLAKGDIIFLADQDDIWMLDKIEKMTDIMTSNESIELLASNVKPFYMGSDPRKVNYEKLKTKKEVVKIENKAKWIKPMRPGCSMCFRNNLLVNYDKLWFEDYAHDALLWGMAVLKGTAYLYNKDTINFRRHDTNASSRVEHKNANRVNKLSKEYRIIEKVSTFRNDKIIKKQIRLYKERIRAIKNKNTLGIIKLVFEINLYSRKRYWLTDIYYCLKN
>NZ_LR699012.1|WP_077325708.1|703331_704402_-|glycosyltransferase
MKRKIVFIINSLKNGGPVNMLYTLIKHVDANKFDMYVIALSKCDPNNERNFNELSCKVVTLSDNENTMKQVNSLIEKINPDIVHSHGGRADLVNSRLKGNFKTVSTVHCDPDEDFAMKKGKIRGWMQATVFINTVKKIQCPIACSETVAKKIEHKRHLNIGYIRNGIDLNRLNINEEITRSELGIGTEDIVLSFCGYLSKRKNASYLINAIKKISRKDIFLLLIGDGKELEDLKKLAGNDSRIKFIGRVPSPIKYLRISDYFVSASLSEGLPLAVMEGMGCGLPAILSNIDSHFEMKKCCEEAVQIFDLEDYEKMIAILNNLERDENKSKAAQKVVFDYLNATRMAKEYENVYSED

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Crispr_ID: NZ_LR699012_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LR699012_2

1448618-1448722

Orphan

Consensus_repeat	Method
ATGTTTCACGTGAAACATTTATTAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LR699012_2

>merge|NZ_LR699012|2|1448618-1448722|CRISPRCasFinder
ATGTTTCACGTGAAACATTTATTAATTTTTGTGCAATTTCGCTTTTATAACTATTACGATTCTTTTCGTTTTTATATTAAATGTTTCACGTGAAACATTTATTAA

>NZ_LR699012|2|2|1448618-1448722|CRISPRCasFinder
ATGTTTCACGTGAAACATTTATTAA	TTTTTGTGCAATTTCGCTTTTATAACTATTACGATTCTTTTCGTTTTTATATTAA
ATGTTTCACGTGAAACATTTATTAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LR699012.1\|WP_077326329.1\|1443278_1444295_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|340424
NZ_LR699012.1\|WP_077326339.1\|1452074_1453958_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	unknown	unknown	gnl\|CDD\|235362
NZ_LR699012.1\|WP_055073373.1\|1441102_1441870_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_LR699012.1\|WP_008392984.1\|1457191_1457434_-\|membrane-protein-insertion-efficiency-factor-YidD	unknown	unknown	gnl\|CDD\|376620
NZ_LR699012.1\|WP_077326331.1\|1444291_1444960_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_LR699012.1\|WP_077326333.1\|1445073_1446360_-\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461
NZ_LR699012.1\|WP_008392998.1\|1442474_1443260_-\|histidinol-phosphatase-HisJ-family-protein	unknown	unknown	gnl\|CDD\|273837
NZ_LR699012.1\|WP_077326337.1\|1451360_1452071_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	unknown	unknown	gnl\|CDD\|234637
NZ_LR699012.1\|WP_008392994.1\|1446372_1446864_-\|DUF4446-family-protein	unknown	unknown	gnl\|CDD\|379655
NZ_LR699012.1\|WP_022091777.1\|1456193_1457195_-\|YidC/Oxa1-family-membrane-protein-insertase	unknown	unknown	gnl\|CDD\|376730
NZ_LR699012.1\|WP_055161067.1\|1438060_1438807_-\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NZ_LR699012.1\|WP_008392999.1\|1442046_1442397_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380350
NZ_LR699012.1\|WP_008392987.1\|1453960_1455337_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	unknown	unknown	gnl\|CDD\|235392
NZ_LR699012.1\|WP_008392992.1\|1447795_1448566_-\|ParA-family-protein	unknown	unknown	gnl\|CDD\|379293
NZ_LR699012.1\|WP_077326327.1\|1439064_1441113_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376899
NZ_LR699012.1\|WP_077326335.1\|1450548_1451301_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LR699012.1\|WP_008392982.1\|1457440_1457779_-\|ribonuclease-P-protein-component	unknown	unknown	gnl\|CDD\|234782
NZ_LR699012.1\|WP_008392981.1\|1457828_1457963_-\|50S-ribosomal-protein-L34	unknown	unknown	gnl\|CDD\|179004
NZ_LR699012.1\|WP_008392980.1\|1458378_1459713_+\|chromosomal-replication-initiator-protein-DnaA	unknown	unknown	gnl\|CDD\|234667
NZ_LR699012.1\|WP_008392991.1\|1448850_1450536_-\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|183534

Protein	Function_ID	Function_description	E-value
NZ_LR699012.1\|WP_077326329.1\|1443278_1444295_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|340424	cd16948, HATPase_BceS-YxdK-YvcQ-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ. This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.	6.9472e-46
NZ_LR699012.1\|WP_077326339.1\|1452074_1453958_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	gnl\|CDD\|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
NZ_LR699012.1\|WP_055073373.1\|1441102_1441870_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	2.63897e-100
NZ_LR699012.1\|WP_008392984.1\|1457191_1457434_-\|membrane-protein-insertion-efficiency-factor-YidD	gnl\|CDD\|376620	pfam01809, Haemolytic, Haemolytic domain. This domain has haemolytic activity. It is found in short (73-103 amino acid) proteins and contains three conserved cysteine residues.	1.25921e-36
NZ_LR699012.1\|WP_077326331.1\|1444291_1444960_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.47584e-67
NZ_LR699012.1\|WP_077326333.1\|1445073_1446360_-\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	8.37714e-175
NZ_LR699012.1\|WP_008392998.1\|1442474_1443260_-\|histidinol-phosphatase-HisJ-family-protein	gnl\|CDD\|273837	TIGR01856, Probable_histidinol-phosphatase, histidinol phosphate phosphatase, HisJ family. This model represents the histidinol phosphate phosphatase HisJ of Bacillus subtilis, and related proteins from a number of species within a larger family of phosphatases in the PHP hydrolase family. HisJ catalyzes the penultimate step of histidine biosynthesis but shows no homology to the functionally equivalent sequence in E. coli, a domain of the bifunctional HisB protein. Note, however, that many species have two members and that Clostridium perfringens, predicted not to make histidine, has five members of this family; this family is designated subfamily rather than equivalog to indicate that members may not all act as HisJ.	4.03204e-46
NZ_LR699012.1\|WP_077326337.1\|1451360_1452071_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	gnl\|CDD\|234637	PRK00107, gidB, 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG.	3.80917e-83
NZ_LR699012.1\|WP_008392994.1\|1446372_1446864_-\|DUF4446-family-protein	gnl\|CDD\|379655	pfam14584, DUF4446, Protein of unknown function (DUF4446). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 165 and 176 amino acids in length.	1.71597e-60
NZ_LR699012.1\|WP_022091777.1\|1456193_1457195_-\|YidC/Oxa1-family-membrane-protein-insertase	gnl\|CDD\|376730	pfam02096, 60KD_IMP, 60Kd inner membrane protein.	3.47232e-53
NZ_LR699012.1\|WP_055161067.1\|1438060_1438807_-\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	1.21243e-75
NZ_LR699012.1\|WP_008392999.1\|1442046_1442397_+\|cupin-domain-containing-protein	gnl\|CDD\|380350	cd02221, cupin_TM1287-like, Thermotoga maritima TM1287 decarboxylase, cupin domain. This family includes bacterial proteins homologous to TM1287 decarboxylase, a Thermotoga maritima manganese-containing cupin thought to catalyze the conversion of oxalate to formate and carbon dioxide, due to its similarity to oxalate decarboxylase (OXDC) from Bacillus subtilis. TM1287 shows a cupin fold with a conserved "jelly roll-like" beta-barrel fold and forms a homodimer.	2.35914e-46
NZ_LR699012.1\|WP_008392987.1\|1453960_1455337_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	gnl\|CDD\|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
NZ_LR699012.1\|WP_008392992.1\|1447795_1448566_-\|ParA-family-protein	gnl\|CDD\|379293	pfam13614, AAA_31, AAA domain. This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.	1.27546e-96
NZ_LR699012.1\|WP_077326327.1\|1439064_1441113_-\|ABC-transporter-permease	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	9.2373e-07
NZ_LR699012.1\|WP_008392981.1\|1457828_1457963_-\|50S-ribosomal-protein-L34	gnl\|CDD\|179004	PRK00399, rpmH, 50S ribosomal protein L34; Reviewed.	7.07629e-10
NZ_LR699012.1\|WP_008392982.1\|1457440_1457779_-\|ribonuclease-P-protein-component	gnl\|CDD\|234782	PRK00499, rnpA, ribonuclease P; Reviewed.	2.79103e-46
NZ_LR699012.1\|WP_008392980.1\|1458378_1459713_+\|chromosomal-replication-initiator-protein-DnaA	gnl\|CDD\|234667	PRK00149, dnaA, chromosomal replication initiator protein DnaA.	0
NZ_LR699012.1\|WP_008392991.1\|1448850_1450536_-\|arginine--tRNA-ligase	gnl\|CDD\|183534	PRK12451, PRK12451, arginyl-tRNA synthetase; Reviewed.	0

>NZ_LR699012.1|WP_008392992.1|1447795_1448566_-|ParA-family-protein
MGRIIAIANQKGGVGKTTTAVNLSAALAARGKKTLLVDMDPQGNTTSGLGLEKNELDKTTYEVITGEEKIQNCIVKDLFDNLSLLPANRNLAGAEIELMTVDKMQFIMKHNLEKVKKQYDFIIIDCPPALGMLTVNAMTAANTVIVPIQCEFYALDGLTQLIYTIELIQKSLNPDLTIEGVVFTMYDARTNLSLQVVENVKSYLNQNIYKTIIPRNVRLAEAPSHGLPINLYDPRSSGAESYDLLAEEVIENGGEN
>NZ_LR699012.1|WP_008392994.1|1446372_1446864_-|DUF4446-family-protein
MTDFFNSVGMEYVVIGLAAALLLALILVIVALVKVGKLKKRYEKFLSGKDGKSLEESIVKRFDKLNEIIVEQDFLEQEIQRIDEEHKSSFSKMEVYKYNAFSDMGGETSFVIALLDHNNNGTLLNGMSSQNATYVYAKEIRNGASKVALSNEEKLTLEKCINK
>NZ_LR699012.1|WP_077326333.1|1445073_1446360_-|serine--tRNA-ligase
MLDIKFLRENPDVVKQNIKNKFQDRKLPLVDEVIELDKENREIKQEVQALRADRNKLSKQIGALMGQGKKEEAEEVKKQVTASADRIEELSEREKVVEEKIKEIMMTIPNIIDPSVPIGKDDSENVELERFGEPVVPDFEVPYHTEIMESFDGIDLDSARKVAGNGFYYLMGDIARLHSAVIAYARDFMINRGFTYCVPPFMIRSNVVTGVMSFDEMDAMMYKIEGEDLYLIGTSEHSMIGKFIDTTTEEAELPKTLTSYSPCFRKEKGAHGIEERGVYRIHQFEKQEMIVVCKPEESKDWYEKLWKNTVDLFRSMDIPVRTLECCSGDLADLKVKSVDVEAWSPRQKKYFEVGSCSNLGDAQARRLRIRVKGENGNYFAHTLNNTVVAPPRMLIAFLENNLREDGSVAIPEVLRPYMGGKESLQPKK
>NZ_LR699012.1|WP_077326331.1|1444291_1444960_-|response-regulator-transcription-factor
MKAKIIIVEDHEPIRNELKILLSKYGYEIIVLDRFDTVVEECLREDVDLILLDINLPFYDGYYVCRAIREKSEVPIIVVTSRDSEIDELMSINLGADDFITKPYNTQILLARISAMLKRTHKEKVNDFLQYQGLKLQLNSSTVIYKDQIIELSKNEMRILYTLLQHKESIVSRDQLMESLWQSNEFIDDNTLTVNVNRVRKKLEAAGLKDFIKTKRGQGYMI
>NZ_LR699012.1|WP_077326329.1|1443278_1444295_-|HAMP-domain-containing-histidine-kinase
MKTKDFFRMEYAQILIYIVFLGLLEVLLFIFEVNYFLMIYLLLIGLILEGVYLCQRYMKKYRYYKKVKAKLDILEQKCMITEMLELPDFAEGEFLYEILQTCNKSMNDEILKYKIEAAGYREYIEMWIHEVKTPLAATRLILENHPSEITRAMDEEMQQINYYLEQALYYARSNSVEKDYLVKELSLKEVVENAVKANAKSLIGNKIKIKIENLDQKIFSDEKWVLFILNQVISNAIKYKKEEAEISFCARCEKNEILLEIRDNGIGISPKDLPRITDKGYTGTTGRNYQKSTGMGLYLCKKLCSKLQLSFYIESKEEEYTKVTIGFPRNSMIFFNEE
>NZ_LR699012.1|WP_008392998.1|1442474_1443260_-|histidinol-phosphatase-HisJ-family-protein
MFADYHVHSHFSEDTDFPMELEIQKAIKLGMDELCFTEHSDYDVPTVVNCDYDAYFEEMEKMKDKYKGQITLKTGIEFGIQTHTTKAYEETFRQYPFDFVIFSCHQVENKEYWRQEPQEGKTQLEYNRRYYQEILDVVKVYKDYSILGHLDVIKRYDKQGEIEFEKIQDLIEQIFEVVIADGKGIELNTSSRAYKLKSLMPSKEILKLYHDMGGKIITIGSDAHNADRIGDCVMESQKILKDIGFDGIYTFEKMKPEFHRF
>NZ_LR699012.1|WP_008392999.1|1442046_1442397_+|cupin-domain-containing-protein
MFLKNEDVKIGTIPDANGSDNPLKKMEFLTEKEMKDSSRLFGKVIVPPGSALAYHTHEGEGEAYHILQGKGLYNDNGTKYEVHPGDTTFTCDGAGHAIENIGDEDLVFMALILLDK
>NZ_LR699012.1|WP_055073373.1|1441102_1441870_-|ABC-transporter-ATP-binding-protein
MSSVLKVDNIEKYYGSKANLTKAIDRISFEVEEGEYIGIMGASGSGKTTLLNCISTIDQVTAGNIMINGMDITKLKGKHLSRFRREELGFIFQDFNLLDTLTAFENIALALTIMKIPAREIEDRVRSIAEKLMITEVLNKYSYQMSGGQKQRVASARAMITNPSLILADEPTGALDSKAARMLLDSMETMNVELNATILMVTHDAFTASYCKRILFIKDGKIFNELVRGNDSRKRFFDRIIEVVTLLGGDSTNVF
>NZ_LR699012.1|WP_077326327.1|1439064_1441113_-|ABC-transporter-permease
MYSKIALSNVKKSIRDYTIYFLTLTFGICLFYMFNSVQAQQAVLKLNASQKSMMHLMSVIINGISVFVAIILGFLIVYANQFLMKRRHKEMGIYLLLGMEKRQVSKILLIETLLIGVLALIAGLVSGVFLSQGLAMLTAKMFAVQMKEFRFVFSQTAFIQTILYFAIIFIIVMIFNGITISKYKLINLLNSAKKNQKARLKNPILSVILFLISIGILGVAYHLIQKNQMLAVDNDFKISVILGVAGTFLFFFSLSGFLLELAKRSKKFYYNGLNMFVLRQINSKITTTFVSMSMLCLMLFLAISAFATGSGLASSVKTDLEDMTKFDYTFYGVSEKGYQEEQQQKFMKRLDALGLTIEKDAKEILPITIYQNGTFRKCRYKMEPLLKGREKYSDYTKDYVKKLYEIPLTFAKLSEYNKIRKAIGEKELTLKSDEYILNCDYGNLIPIMEKAASDKQKLTLDGKTYKMKYGLQKDTYMVTAAKTDMGTVILNDEIIQSLKIDYSTLYLNINWKGNAQKASKHYNEHLKQMIANSKMKNSPYSATVSKEEVYEQSTGLSTIMTYIAIYIGLVFLITCAAVLALQQLSENADNIEKYQLLSKIGTSQKMINHAIKAQIILYFCLPLSLALIHSYVGIKTAKILISTLGQINITKAAAQSLIIVIVIYIGYMIATYLGSKSMLKEK
>NZ_LR699012.1|WP_055161067.1|1438060_1438807_-|DeoR/GlpR-transcriptional-regulator
MLAQERFERILEILREKQSVTVVELTEKLNTSESTIRRDLTELNRQGLLIKVHGGATAIKSVLSREEEVITKSKKHQEEKRKIAKYAASLINKEDIVYLDAGTTTEMMLDYLKEYDVVYVTNGITHARKLMNAGFKVHLIGGEIKAVTEALVGEEALEQLDKYNFTKGFFGTNGIDLKRGFTTPDQKEAAVKKKAMEQCQKRYILSDASKFNVISTIKFADLKKAEVITDHLENKEFKRITNIEEVFS
>NZ_LR699012.1|WP_008392991.1|1448850_1450536_-|arginine--tRNA-ligase
MRNKVIDLLDQTIEELDKEKIDGILEIPPKDDMGDFAFPCFQLAKVFRKAPNMIATEIAEKIPASEDVSKVEAMGPYVNFFLNKENYVKEVLAKVNGTYGAQEIGKGKTVCIDYSSPNIAKNFHVGHLRTTIIGNSLYHIFDKLGYKVERINHLGDWGTQFGKLIVAYKKWGSKEAVEEKGIPELLRIYVKFHEEAEKDDTLNDQAREWFAKMEQGDEEALSIWEWFKDISMVEYKRIYKMLNMDFDHYTGESFYRDKTAAVVEELKEKNLLKESEGAMIVDLDEYDMAPCLVMKKDGSSIYATRDLAAIFYRKKEYNFDKCIYVTGLEQKLHFAQVFKVVELMGYEWAKENLIHVPYGLVSLEGGKLSTRSGNIVYAEDILKESVSKIREIIAEKNPDLKDKEDVAQKVGIGAIIFNDLYNQRIKDVTFTWEKIHSFDGETGPYVQYTYARAASVLRKTGITEVGEIDPSLVTDETSVALLKEIERFPEVIKVAADRLEPSVISRYVMGVAQSFNRFYHENQCNVEDQKLKEARVKIVILAKQVIKDGLDLLGIQCPEQM
>NZ_LR699012.1|WP_077326335.1|1450548_1451301_-|hypothetical-protein
MEKNKDKSHLIDQLYDYLEEQIQELKTDRNQLNHKMQDMIQEKNEKEGAINNQQKIYQIRKVFSPLPLEIEEEKQPVSEDMIQIEKEIHEFQMILREKEEKITKLHDYQKGLEETCLFAEEFVEREDQKILFVPAFEQLMGYVKKLYPTQRINYQDSSESSKVCMTFSFLKGFQAVLESLLNEIGVFVLNFEINIDEYKILINIEAKPKVIKNAKDFYEKRSVLENKLTKEFSIERWKTNAVVIQTMIEM
>NZ_LR699012.1|WP_077326337.1|1451360_1452071_-|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG
MERLREKAAAFGIKLSDHQLEQFETYYEMLVEKNKVMNLTAITEKNEVIDKHFADSLALIKSGVSLTGQKILDIGTGAGFPGIPLKIAFPELEIVLLDSLNKRIKFLNEVIEALGLEKITAIHGRAEDFAKQKEYREQFDYVVSRAVANLTVLSEYCLPYVKEDGYFLPYKSGDIKEEAANSKKAVKILGGSIEDIVSFEIPDTDMARTILKIHKTKATPKRFPRKAGLPTKEPIC
>NZ_LR699012.1|WP_077326339.1|1452074_1453958_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG
MNNLEEKYDIIVVGAGHAGCEAALAAARMGFETICFTVSMDSVALMPCNPNIGGSSKGHLVKEIDALGGEMGKNIDKTYLQSKMLNKSKGPAVHSLRAQADKKMYSISMTQVMGNTPNLTLRQGEVTEILVEDGKIKGVKTYSGAVYYAKAVVLTTGTYLKARCIYGEVSNHTGPNGLQAANYLTDSLKSHGISMRRFKTGTPARIDKNTIDFSKMAEQFGDERIVPFSFTNKEEDIKRDQISCWLTYTTEETHEIIKENIHRSPLFSGAIEGTGPRYCPSIEDKIVKFPDKNRHQVFIEPEGEYTNEMYVGGMSSSLPEDVQYKMYHSVPGLENAKIVRNAYAIEYDCIDATQLKASLEFKEIDGLFSGGQFNGSSGYEEAAAQGLMAGINAARKLQEKDPIILDRSQAYIGVLIDDLVTKETQEPYRMMTSRAEYRLLLRQDNADLRLTKIGYEAGLISQERYDKLLVKEQQIEDEMKRLEDINVGASKNVQSLLEELGSTTLKSSAKMTELIRRPELTYMGLAPIDPERPEYDLDVQEQVNINIKYEGYIKRQLSQVKQFKKMEKKRIPEDIDYEDVGSLRIEAKQKLSKIRPSSIGQASRISGVSPADISVLLIYLEQMHHRR
>NZ_LR699012.1|WP_008392987.1|1453960_1455337_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE
MKSNTIAAIATPMTNSGIGIIRISGDEALDIIEKVFKPKKKDKKIKDVKTYTAHYGHVYDESTLLDECIVLVMKGPHSYTAEDVVEINCHGGVVVMKKVLEAVFKAGATPAEPGEFTKRAFLNGRIDLSEAEAVMDLIQSKNEFAMSTSLKQLEGALGKKITEIRKQIIHSVAFIESALDDPEHYSVDGFSDELKDQVEVIINQLNEFLENADNGRILKEGIQTVIVGKPNAGKSSVLNVLLGEERAIVTDIAGTTRDTLEESIQIKGIPLNIIDTAGIRDTNDLIEKIGVDKAKDLLTKADLVLYVVDTSDPLTKDDEEIMELIEDKQTIVLLNKADLDQVVKVSDLKEKGFEQIVQISAKEQTGIEELYQLIQDIFFEGHVSFNDEIYLTNMRHKTEVSEALKSLAMVLQSIEDGMPEDFFSIDLLDAYEHLGFITGESVGEDLVNEIFAEFCMGK
>NZ_LR699012.1|WP_022091777.1|1456193_1457195_-|YidC/Oxa1-family-membrane-protein-insertase
MMLLAQAQQSTGNGGILAPFVIIFGWIIRAIYNGLAAMGIYNVGLCIILFTLVSKLILLPVTMKQQRSMKINQHMQPEINKITKKYRNKRDQASMMKQQEEMQKVYAKYGSSPTGGCLPTLIQFPIIMALYYVIRGVNTYIPQIARDAQFKPNLFLGMDLNSAPGFRLTPLLIIPVLSFIFQFLSAKTSMSTTQMDDSTPGAGMTKSMMYTMPLMSFVMCISLPIGIGLYWSASALFQYIQQVAFNYHYDHADMDKIIEKSREKAAKKKKKKGPSLYEKMLGMQAEQQGQQGADSNIKKSANLKSTQNIEYSGNSKGGIASKANALNKNKGGK
>NZ_LR699012.1|WP_008392984.1|1457191_1457434_-|membrane-protein-insertion-efficiency-factor-YidD
MKKILISIIRFYRKYLSRLKGRGTCIYVPTCSEYAIEALEKHGVVKGSLLAIFRILRCNPFSKGGYDPVPEVRKGKRCKK
>NZ_LR699012.1|WP_008392982.1|1457440_1457779_-|ribonuclease-P-protein-component
MKNYHSLRNNREFQMVYNEGNSKANRYLVLYYRKNDLEYNRLGISVSKKVGNSVVRHRTTRLIRESYRLNQDNLKTGYDMVVIARQTAKGQNYHTIESAFLHLIDLHHLKKS
>NZ_LR699012.1|WP_008392981.1|1457828_1457963_-|50S-ribosomal-protein-L34
MKMTFQPKKRQRSKVHGFRKRMSTANGRKVLKSRRAKGRNRLSA
>NZ_LR699012.1|WP_008392980.1|1458378_1459713_+|chromosomal-replication-initiator-protein-DnaA
MKNEIEKIWDDVLVKLEQEHDVSSAAINAWIKPLHIKDVQSNKIILSLDAKYDERGIQFIKKKMYDFYISLAISDLTGKKYDIEFELEKEGEKPQETPAAAPEHDNNNLNPRYTFDTFVIGDNNRMAHAASIAVAEAPAEAYNPLFLYGGAGLGKTHLMHSIAHYIIEHNSSLNVLYVTSEDFTNEVINSIQHKKQEELRSKYRNIDVLLVDDIQFVIGKESTQQEFFHTFNALYNSKKQIILSSDKPPKELDVLEERLRSRFSWGLPVDIQPPNYETKVAILRKRAELDNIYIDDEIFDYIATHIKSNIRDLEGALNKIKVYSKLNKKPIDLELSKIALQDLIDNKTKQAITPELIMQTVAEHFNIQTSDIISKKRSHDIAYPRQICMYLCKKMTDQSLVKIGEIIGKRDHSTVIHGIEKIEKDLDKDPELSKVIDVITKKMD

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Crispr_ID: NZ_LR699012_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LR699012_3

2887571-2887673

Orphan

Consensus_repeat	Method
GGACATGAGCCAGATGTTCTATGGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LR699012_3

>merge|NZ_LR699012|3|2887571-2887673|CRISPRCasFinder
GGACATGAGCCAGATGTTCTATGGAATGGATTCGATCAAGACGCTCGACTTATCATCCTTTAATACATCCAATGTTGAGGATATGAGCCAGATGTTCTATGGA

>NZ_LR699012|3|3|2887571-2887673|CRISPRCasFinder
GGACATGAGCCAGATGTTCTATGGA	ATGGATTCGATCAAGACGCTCGACTTATCATCCTTTAATACATCCAATGTTGA
GGATATGAGCCAGATGTTCTATGGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LR699012.1\|WP_055232729.1\|2896160_2896475_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LR699012.1\|WP_055232726.1\|2895279_2895582_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|368240
NZ_LR699012.1\|WP_077327279.1\|2876701_2877460_+\|antirestriction-protein-ArdA	unknown	unknown	gnl\|CDD\|377800
NZ_LR699012.1\|WP_077327277.1\|2875229_2876690_+\|DUF1738-domain-containing-protein	unknown	unknown	gnl\|CDD\|226680
NZ_LR699012.1\|WP_077327287.1\|2881440_2882262_+\|class-C-sortase	unknown	unknown	gnl\|CDD\|320676
NZ_LR699012.1\|WP_077327297.1\|2899170_2899977_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LR699012.1\|WP_077327285.1\|2880601_2881444_+\|class-C-sortase	unknown	unknown	gnl\|CDD\|320676
NZ_LR699012.1\|WP_077327273.1\|2874012_2874852_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379352
NZ_LR699012.1\|WP_077327289.1\|2882297_2883806_+\|InlB-B-repeat-containing-protein	unknown	unknown	gnl\|CDD\|380193
NZ_LR699012.1\|WP_055232727.1\|2895568_2895838_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl\|CDD\|376852
NZ_LR699012.1\|WP_155496493.1\|2898228_2898390_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LR699012.1\|WP_055073318.1\|2896509_2897724_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|341491
NZ_LR699012.1\|WP_158520191.1\|2877477_2878500_+\|nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|377262
NZ_LR699012.1\|WP_055159875.1\|2900148_2900460_+\|DUF4258-domain-containing-protein	unknown	unknown	gnl\|CDD\|379454
NZ_LR699012.1\|WP_077327271.1\|2873722_2873992_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LR699012.1\|WP_077327275.1\|2874966_2875173_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LR699012.1\|WP_077327291.1\|2890291_2890519_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LR699012.1\|WP_077327295.1\|2894763_2895156_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LR699012.1\|WP_077327293.1\|2891143_2894524_+\|Ig-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|227604
NZ_LR699012.1\|WP_077327283.1\|2878649_2880599_+\|SpaH/EbpB-family-LPXTG-anchored-major-pilin	unknown	unknown	gnl\|CDD\|380024

Protein	Function_ID	Function_description	E-value
NZ_LR699012.1\|WP_055159875.1\|2900148_2900460_+\|DUF4258-domain-containing-protein	gnl\|CDD\|379454	pfam14076, DUF4258, Domain of unknown function (DUF4258). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 95 and 124 amino acids in length.	4.33585e-27
NZ_LR699012.1\|WP_055232726.1\|2895279_2895582_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|368240	pfam05016, ParE_toxin, ParE toxin of type II toxin-antitoxin system, parDE. ParE is the toxin family of a type II toxin-antitoxin family. It is toxic towards DNA gyrase, but is neutralized by the antitoxin ParD. The family also encompasses RelE/ParE described in.	0.00158723
NZ_LR699012.1\|WP_077327279.1\|2876701_2877460_+\|antirestriction-protein-ArdA	gnl\|CDD\|377800	pfam07275, ArdA, Antirestriction protein (ArdA). This family consists of several bacterial antirestriction (ArdA) proteins. ArdA functions in bacterial conjugation to allow an unmodified plasmid to evade restriction in the recipient bacterium and yet acquire cognate modification.	3.05878e-10
NZ_LR699012.1\|WP_077327277.1\|2875229_2876690_+\|DUF1738-domain-containing-protein	gnl\|CDD\|226680	COG4227, COG4227, Antirestriction protein [DNA replication, recombination, and repair].	2.52178e-59
NZ_LR699012.1\|WP_077327287.1\|2881440_2882262_+\|class-C-sortase	gnl\|CDD\|320676	cd05827, Sortase_C, Sortase domain found in class C sortases. Class C sortases are membrane-bound cysteine transpeptidases broadly distributed in Gram-positive bacteria (mainly present in Firmicutes and Actinobacteria). They function as pilin polymerases responsible for the assembly of pili, which are multi-subunit hair-like fibres that extend from the cell surface to promote microbial adhesion and biofilm formation. First, one or more class C sortases form the long thin shaft of the pilus through linking together pilin subunits via isopeptide bonds. The base of the pilus is then anchored to the cell wall by a housekeeping sortase or, in some cases, the class C sortase itself. Depending upon the organism both the number and type of sortase enzymes involved varies, and in some cases, accessory factors appear to be needed. In three-component spaA pilus from Corynebacterium diphtheriae, the prototypical class C sortase (named Cd-SrtA) catalyzes polymerization of the SpaA-type pilus, consisting of the shaft pilin SpaA, tip pilin SpaC and minor pilin SpaB. The pilus shaft is then attached to the cell wall by a housekeeping class E sortase, Cd-SrtF. In the absence of Cd-SrtF, Cd-SrtA attaches the pilus to the cell wall, albeit at a reduced rate. Cd-SrtA can recognize two distinct sorting signals (LPLTG in SpaA and SpaC, and LAFTG in SpaB) and it can employ lysine residues that originate from different proteins (either Lys190 within the pilin motif of SpaA or Lys139 in SpaB). However, Cd-SrtA cannot be able to polymerize the major pilin subunit SpaH, even though it contains LPLTG motif. In two-component pili of prototypical Bacillus cereus, the class C sortase (named Bc-SrtD) cleaves related sorting signals within a major pilin protein BcpA (LPVTG) and a minor tip pilin BcpB (IPNTG), and catalyzes a transpeptidation that joins the threonine residues in each signal to the side-chain of Lys162 in BcpA (located within a pilin motif). Unlike the SpaA pilus in C. diphtheriae, in B. cereus Bc-SrtD is unable to covalently attach the pilus to the cell wall without the help of the housekeeping sortase.	6.04911e-70
NZ_LR699012.1\|WP_077327273.1\|2874012_2874852_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379352	pfam13730, HTH_36, Helix-turn-helix domain.	1.09385e-09
NZ_LR699012.1\|WP_077327283.1\|2878649_2880599_+\|SpaH/EbpB-family-LPXTG-anchored-major-pilin	gnl\|CDD\|380024	pfam17802, SpaA, Prealbumin-like fold domain. This entry contains a prealbumin-like domain from a wide variety of bacterial surface proteins. This entry corresponds to domain 1 and domain 3 of SpaA from Corynebacterium diphtheriae. Some members of this family contain an isopeptide bond.	0.000194124
NZ_LR699012.1\|WP_055073318.1\|2896509_2897724_+\|hypothetical-protein	gnl\|CDD\|341491	cd17792, CtkA, serine/threonine-protein kinase CtkA and similar proteins. The Helicobacter pylori serine/threonine-protein kinase CtkA (proinflammatory kinase), encoded by the jhp940 gene, has been shown to be secreted by the bacterium and to induce cytokines in gastric epithelial cells. It may play a role in chronic gastric inflammation. CtkA autophosphorylates itself at a threonine residue near the N-terminus and it translocates into cultured human cells. It also enhances phosphorylation of the NF-kappaB p65 subunit at Ser276 in human epithelial cancer cells; phosphorylation at this position is known to activate the transcriptional activity of NF-kappaB.	4.33906e-13
NZ_LR699012.1\|WP_158520191.1\|2877477_2878500_+\|nucleoid-associated-protein	gnl\|CDD\|377262	pfam04245, NA37, 37-kD nucleoid-associated bacterial protein.	6.27908e-31
NZ_LR699012.1\|WP_077327289.1\|2882297_2883806_+\|InlB-B-repeat-containing-protein	gnl\|CDD\|380193	NF033189, internalin_A, class 1 internalin InlA. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface or secreted proteins with an N-terminal signal peptide, leucine-rich repeats, and usually a C-terminal LPXTG processing and cell surface anchoring site. See PMID:17764999 for a general discussion of internalins. Members of this family are internalin A (InlA), a class 1 (LPXTG-type) internalin.	3.74755e-08
NZ_LR699012.1\|WP_077327285.1\|2880601_2881444_+\|class-C-sortase	gnl\|CDD\|320676	cd05827, Sortase_C, Sortase domain found in class C sortases. Class C sortases are membrane-bound cysteine transpeptidases broadly distributed in Gram-positive bacteria (mainly present in Firmicutes and Actinobacteria). They function as pilin polymerases responsible for the assembly of pili, which are multi-subunit hair-like fibres that extend from the cell surface to promote microbial adhesion and biofilm formation. First, one or more class C sortases form the long thin shaft of the pilus through linking together pilin subunits via isopeptide bonds. The base of the pilus is then anchored to the cell wall by a housekeeping sortase or, in some cases, the class C sortase itself. Depending upon the organism both the number and type of sortase enzymes involved varies, and in some cases, accessory factors appear to be needed. In three-component spaA pilus from Corynebacterium diphtheriae, the prototypical class C sortase (named Cd-SrtA) catalyzes polymerization of the SpaA-type pilus, consisting of the shaft pilin SpaA, tip pilin SpaC and minor pilin SpaB. The pilus shaft is then attached to the cell wall by a housekeeping class E sortase, Cd-SrtF. In the absence of Cd-SrtF, Cd-SrtA attaches the pilus to the cell wall, albeit at a reduced rate. Cd-SrtA can recognize two distinct sorting signals (LPLTG in SpaA and SpaC, and LAFTG in SpaB) and it can employ lysine residues that originate from different proteins (either Lys190 within the pilin motif of SpaA or Lys139 in SpaB). However, Cd-SrtA cannot be able to polymerize the major pilin subunit SpaH, even though it contains LPLTG motif. In two-component pili of prototypical Bacillus cereus, the class C sortase (named Bc-SrtD) cleaves related sorting signals within a major pilin protein BcpA (LPVTG) and a minor tip pilin BcpB (IPNTG), and catalyzes a transpeptidation that joins the threonine residues in each signal to the side-chain of Lys162 in BcpA (located within a pilin motif). Unlike the SpaA pilus in C. diphtheriae, in B. cereus Bc-SrtD is unable to covalently attach the pilus to the cell wall without the help of the housekeeping sortase.	7.7915e-81
NZ_LR699012.1\|WP_077327293.1\|2891143_2894524_+\|Ig-like-domain-containing-protein	gnl\|CDD\|227604	COG5279, CYK3, Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain [Cell division and chromosome partitioning].	8.66807e-12
NZ_LR699012.1\|WP_055232727.1\|2895568_2895838_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl\|CDD\|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	0.000774905

>NZ_LR699012.1|WP_077327289.1|2882297_2883806_+|InlB-B-repeat-containing-protein
MKKEKKNMRWKIVAALVVTTFVSVLTWHQMKNAHAYGTYDTGGNKHFVDGHLTVNMSGPNGKSDSLTMYIHSDDYEKNKNVSGGKFNNSKHPYTVTTYSGGGGDYKLTVNKQTIYSEKNSNNNYTLLTIKVWYLLPAHEQHRSWEWVTVDKPTFSDPSKDITLYCGGNDGFWENSYHDTQEHWKSVNIHVSTGLVGVASTDRDGWKTYDWCSINLNLEKPSRSIYYNGNGGTGADVTWNFTDGDNFSFPTVSRRGYTLDGWLDQETGWMSNTGWLVCNNYTEIAQWTANSYNIYYDGNGEDSGWVSDGTATYDLNYTFATNGYKKKGYSFVGWSTDKYATTAQYSPGQTITWTDIDGMTLYAIWSKSSYEVSFDGNGASGGKKTADLKYGQDDKLPANTFERPGYTFMGWSENPDAVKPKYTDGQTVNTLCDAGKTYELYAVWKKTDGSFDTHNIIHDDGMFNGSIELEGQNGTGFSRDHVDSEYGRIDKDGQPGYFTNRYK
>NZ_LR699012.1|WP_077327287.1|2881440_2882262_+|class-C-sortase
MKHKLITITGWLFLFLSIGLLLYPEIISFIQQKESDQVVQKLEENRNREKKNDLLYQKSARYNDRISKNGQKDLKDVWSYKQAPIILRNEDRTFGYIKIPKMKQKLPLYLGATMENMRKGAAIMGQTSLPLGKRDSNCVIAAHRGYQGIPYFRDIEELKIGDLVIIRNPWERLSYKVTKIKVIDPYDTDKILIQKGKDMITLLTCHPYREHGKYRYLVYCERNHGQKIKKQERTQLGDSSRKMIEEEKWIRYAGMFLLILTGGVWLRKREQGR
>NZ_LR699012.1|WP_077327285.1|2880601_2881444_+|class-C-sortase
MRQKIIPVLIVLAGFLLLSYPFMSNYLFERSAGSMVRSYGKKTAGMNQEMKEKALDEARRYNEELLSSSIQLTDPFKAKKTDGETLFYNNILSLEGSGIMGYVKIPCISVNLPIYHGTSAEVLERGIGHLAASSFPIGGKSTHAVLTGHTGLSSAKLFTDLTEMKKGDLFFIHVLDKKLAYRVDQINVIRPEDTRKLQIIDGKDYVTLLTCTPYGVNDHRLLVRGIRTEYHEKEELTKERPHHSQWMVVYRRAILIGLLIVFLLVGSRKMYRRIKGRRKK
>NZ_LR699012.1|WP_077327283.1|2878649_2880599_+|SpaH/EbpB-family-LPXTG-anchored-major-pilin
MRIKNIIRKATVAALTAVMILAPIVNVKAASSDVIDTSKTGSLTIHKYDMTAAKQAGVNLDQFTSTGKQDTNAEQALKKYAIKGVEFSYLRVGDVEQQSENGKIQMIYELPSALQQIIGLAPSDAAKTEGNKTYFTSQKINDKLAHALEDNTATKDKLEDYMGKSGTAMAETNASGVTSKDKLPLGLYLIVETKVPEDVTYTTNPWFVQLPSTDSNGDDWFYDVVCYPKNETGYPTLDKRVRNNPDQDNVTTANADKLADFTSARNEYKYQSTVTASKAEKLDYQFISKLPHITSSTTYLSTYTFDDTMAKGMTYSKDAVIAIYDSKDAADSTNVNNVDRSGAIAVWKSSDAETKFSATYGTSGDDPTMKIEMTKAGLNELNKKYSDKYIVVYYTAKVNTNDSVVLGDKGNPNDVSLTWKRTSTNYYDILKDKCIVYSYGYDLTKKFSDDKGDAIKVRFVVKNKTDNYYLVATGSNGVYQVTGKSATEADATQFSPSSAGKLVINGIEADEYAFTETHSDAGYSLLKKDITVKVTETKANITPTIANITGIQSKADTDSTANDGVANGTALNNNVTVQTIAASATVDDTKATMTKHGESDNAYINMEVINQKQFLLPLTGGTGSYLLIIVGVVVAGCGVMVLRRNKKVA
>NZ_LR699012.1|WP_158520191.1|2877477_2878500_+|nucleoid-associated-protein
MIILSDDIIFRKAVIHLLNVELGKFAPAQDLFMMQPDVIELVRKQVCYLLNSDELKAADWNTKEPVFQKLEQMNEKDDKSFIQTSAYLADRLFGIMCDSVEIPSADLLCLSFQTNQEIYYALIKLNYQNSFMHELMKYDNEEIIGNIRHKKILPLGKRISEGIIFNLSLQKVMLKEKKYEMLNGDKIYYLTERFLRSIAQTEAKRKYQILSRTIKTINKKYPEDGLEYQMDTKSKLCKIFEEDQEFSINKIGDELFGKNPQKKMEFDEKMERYNMQYDKFTVEKEETIKDLGYIKLQTNNEIEIKIPMEEYQTKECIKVEEEPDGTKTIVMKNIEQVTVE
>NZ_LR699012.1|WP_077327279.1|2876701_2877460_+|antirestriction-protein-ArdA
MKDVKVYAQNLRSYNIGLDQGRWITLGIEEQELQRILTEQLHLTKNHPDMAIFDYQADFEISEYEDIYELNQAVAQLKQLPEQDYEKVMDYCDARDITSPLEISNVCLQADEVPYERFPDWIDENVKDPEEKLGYALFENNSLAPEIKAAGMEGYFDYKAYGRDEAINSYDIGDHGFVNKRISIDVEKYSYEEIQNQLKENGLDESMEYKEENTWKSEENFWSDEATYEQETYMASDNEIIVEEDIEITMDN
>NZ_LR699012.1|WP_077327277.1|2875229_2876690_+|DUF1738-domain-containing-protein
MAKSKGKTASQIVSESRQELVDQLIQKMKDGVSPVREMWDSVSTYGLPNNPISGARYQGVNLLRLLIASAVGKYEDSRWMTLKQANKQGYRIKKGAKSVLLEKWVWSKIVEEENENGELEKKIVKLKNPYVNFFRVFNAEQIDGIGPIPKVIPMEKNEMLKLAEEVIASSQCEIVESMQNRSYYSPKEDKIMLPPRDYFKSQEAFLAVTLHEMSHSTGHPDRLNRPLVNKFGTPEYAKEELNAEFGSAFLQMDLGIKLSDEAINDHAAYLHSWISVLENDPNELFRAVHNASEISDYLIENYQEYQAEQQHDMQQKQISKIQSEELSNSGNAILRVAIKRAVKAGSIEAGVKYLEKSELRHPDDVEGHRLVKEKFLENIKEFLPEQQEADMQEKEKQNVFPEEVIAEAEMLGFSSVEELQDKIKHGMPTKNYDTSELIHQVSEALDGNYKQENLWEANQESLSKEAKYEQPDIVINESEMELDLEI
>NZ_LR699012.1|WP_077327275.1|2874966_2875173_+|hypothetical-protein
MRNSITNWDVKTNDLTWIQKMVAGPENIDGLEWVDEDELTGEEITDIRQLEAFGVTEQSLKKFKKSNM
>NZ_LR699012.1|WP_077327273.1|2874012_2874852_+|helix-turn-helix-domain-containing-protein
MEMFTSFKKVMADPEITTAGKSVFLNLLSRMDKKGYCYPAVNTMEDETGYCERTIQRQTNKLAEKGYIVKAEQKAMGKQFTNRYYLTPEDKRDFLFNDNDIKEVVRKNSVFQDFLKMEEVIVTTEYKHHCLHLVYRSMKITKLEKLVLAYFIMRADQEAFTYFSVERLSGILRIPFFKLRRVIKTLIYRKLLRISQQIIEGETVIFARICIEKFGLKSFVRKCVKLIRHTYSIQDIKIYLYIVSIRTKTEYKEIQKKYRFHRILQKIQMIQDLDRHVLF
>NZ_LR699012.1|WP_077327271.1|2873722_2873992_+|hypothetical-protein
MNQRQGKIVSLVVAVIVMVVLITIAVIVNRPQKKQTKRSAATTTEVSTEKKQTEETTEEEQMTEAPKDTSDWEMQPAENTEPDTGEKIK
>NZ_LR699012.1|WP_077327291.1|2890291_2890519_+|hypothetical-protein
MKKNKDEEINKEIVKSVISRGIPVEKFFELGGEIIKLDTSPNSTHVNVFEMAGIDPKKVEENTKLINDLINSMKE
>NZ_LR699012.1|WP_077327293.1|2891143_2894524_+|Ig-like-domain-containing-protein
MKQWKQRIACLLAVVMTMTGFFPWNSPVSVHAEESVIKSSADGFEYRLKVYESGIKEYICTSDTTQVYDNYQDAVKGLADISRKILTERKAEPFTVKIPVEIKADQKVDGIEKGSNPFNDAVHKETYKETGNPNEGQGLAQFLDARGNLLNDKLDKITYDETTKSYKGVFYYHMLSHQYAERYSKTITKLKEVIDSLNLDEKSDYEKCKTIREWIGKNVKYDREYAKDPANCSRRNAHDMTGAILDGYAVCDGYANLFHYMANATGLLTLFEEGYQIGSGLQHAWNLVKIDGTFYYTDCTSIALDKDGNATGEFLLGQDTMFNLTVTPKNNDIENTYSNISKDDWSKEHSVCKGNHNLVKTGEGPATCETMGYTGYYCTNQGCIYRYRDYNKEPLGHNYDYTNGEITQSQDCTHPEITTYRCTRCKAPIEVETKPSLGGHKWQPGDIIKAPTCTVNGEQEYTCTVCNQTKTEPVKATGHDWQINKILSAATCTSNGIARYICKTCGYGENHTINATGHKPEIRNKKEATCSSTGYTGDTYCSVCNKKLSSGETINKKEHTWVKQDNIPATCEKGEMEVEKCSVCGETKETQISDPLGHDFREWKITKEPTCTKYGTKKRICKRCNEYEIDVIDPTGHQHTKIIDKKAATCEEKGYSGDLYCEDCRVIIQLGQEIAATGHTWDNGEITKEPTQTATGIRTYTCKTCQKTRIETIPMLKGHHWGNGTVIKEPTCTESGEKIYHCTDEDCNESYTETIKATGHQHTKLINKKDATCEEKGYSGDTYCEDCKQIIKTGKAINPTGHDWDKGTVKKAATCESEGIREYTCNTCKKTKEETIASTGHTKTEIRNKKAATCKEEGYTGDTYCVTCGKKLAEGKAIPKTDHDWTITETPATCEKDGVRTYICDVCHTTKSEPIKAIGHSYGAWTTTKEATISSKAEQQRTCSTCGKEEITTYGEKLRPTISTNATSLKLKKKQTTKKFTVTGLAKGDYITSWTSSNKKIVTVTGNQNGTCKIKAGSKTGKATITIKLASGLTKQIKVTVQKKAVTCSKIKNVPKTIKLKKKQTYQLKPVINPITCTNKIKYKSSNKKIAKVSSTGKITAIKPGKVKITISVGKKKFVSNVIIKK
>NZ_LR699012.1|WP_077327295.1|2894763_2895156_+|hypothetical-protein
MEKVETQITKGLTEETTEEITLLGHILENADGLKVFSELINHVISENAESILLEKKKLLAILQVEEDDLDEMMKKIIDDIIRSQIEIIEKEHKKTGFKIVSIFEMVTYDPEEGLTTQITKAVKPYLKNLI
>NZ_LR699012.1|WP_055232726.1|2895279_2895582_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MKKYKIQLNARAYRDLEEIFEYIANDLQSPEYAKGQTDRLWKSLKTLEIFPSSHQERLVGNYAGKGYRQLLIDNYLAIFKIDEQRKIVKIITIQYQGRNL
>NZ_LR699012.1|WP_055232727.1|2895568_2895838_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MPLIMPIRDLRNTSEISELAHKQQEPIFITKNGYSDLVVMSSELYDQFIKTNRIDQIIYESEKEMNEGAKSIDLDDAFKKLSKKYYEEI
>NZ_LR699012.1|WP_055232729.1|2896160_2896475_+|hypothetical-protein
MLDVKELEKTKRVNIVGEIPDVRLQILDNNGKIKEFRLREMTIAGARTEIDQCNRENYCVYYKGVVEILDRFHINSYKKTFKYILKSKKWFICGNYDDIIKAHR
>NZ_LR699012.1|WP_055073318.1|2896509_2897724_+|hypothetical-protein
MFLENEFYLMNKDDRILRFTCDNSPLGVSFKEEESYEEIRPYGYDGIGQWISQRQAPKHRQYIADLLRMCGCYNLDGFIRVTHALSLNDTFWIKTVDSKLQWKNVSLYENQFDETIAKIAFEGGLYGKEFTTTSPEFGTSGSFAKCWVKEDDGIYLLKRGSEGARNAGLEPYSEMYSSQIARIICRDAVEYSVEKYHNKIASKCRLFTSEQEGYVPITKFFGKIVSVKEILEKFEQHGCEDDFRRMIVLDALILNTDRHMGNYGFMVDNDTMQIKRMAPMFDHNQALLPYAEQEDFENLDVYLASRPTQIGEDFNEIAHALLTPEIRNDLKNLRGFEFQRNDEFDLPEERLQKLNKLVDQQIDGILECKRLYVPSNEYENVRYQPEQYDDLSPESKEIDEELEI
>NZ_LR699012.1|WP_155496493.1|2898228_2898390_+|hypothetical-protein
MRYVIGIIAGVVLIMGAVGGMENDTLNITYSLKMMVIGVILIYECYIIRQKKR
>NZ_LR699012.1|WP_077327297.1|2899170_2899977_+|hypothetical-protein
MTKNDIVNELNKMGYEVREENVVKNSVEFLGISIIDSDRYMIPVFYVEDIITKAEQSGATVKEIVRDMLKIHNDALRESEELNKPIHFNREDFLKRLYVGVQKESKEDIVKCKTEFEGIEKYLFLRMEALNDAIYSAKISKNILKNVDVDESEAWETAENNVRKETEIIQLSGFPMSAEECEMFVISNKSRFRGASAVLNKKVMKAFANLVNTKKIMILPSSIHEMILIPCHDCEYDIESCSEIVKLVNENEVELTEQLTDRAYIIEV
>NZ_LR699012.1|WP_055159875.1|2900148_2900460_+|DUF4258-domain-containing-protein
MNIKIYQKLCAESKILWTQHCLQRMQERDISRLDVKNGIATGEIIEDYPDDYPNPSCLIFGYNVNGHILHIVAGCDNINIYIITAYYPDTKKFENDLKTRRKR

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Crispr_ID: NZ_LR699012_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LR699012_4

3066058-3066991

Unclear

Consensus_repeat	Method
GAATTAATAGAAACATAATGGAATTTAAAG	PILER-CR
GAATTAATAGAAACATAATGGAATTTAAAG	CRISPRCasFinder
GAATTAATAGAAACATAATGGAATTTAAAG	CRT

13 spacers

cas6,cas8b2,cas7,cas5,cas3,cas4,cas1,cas2

The CRISPR arrays of NZ_LR699012_4

>merge|NZ_LR699012|4|3066058-3066991|PILER-CR,CRISPRCasFinder,CRT
GAATTAATAGAAACATAATGGAATTTAAAGTCTATTGTCATTTTTCCGCAATACTCTTTCCAGTTCGAATTAATAGAAACATAATGGAATTTAAAGACAATCAGGCGTAATCATTTCCAGTAACTCAATAGCAGAATTAATAGAAACATAATGGAATTTAAAGGAACTACAGACACTTTTTTCTATTATTGGTTATAATGAATTAATAGAAACATAATGGAATTTAAAGATCGTTGTAGTTAACGTATTAGATCCGGCAAAACACGAATTAATAGAAACATAATGGAATTTAAAGCAGGCTGTAAGTGATAAAGCCATAACTGCGGCTAATCCGAATTAATAGAAACATAATGGAATTTAAAGTTGTTCAAACTCCTTTCTTTCTTCCTCGTCTTCATCATGAATTAATAGAAACATAATGGAATTTAAAGTATATTCTTCTATGAAAGTATTATCATCACTGAAAAGAATTAATAGAAACATAATGGAATTTAAAGCAAAAAGCACAAATAAATACACGGTATACACAGTAAATGAATTAATAGAAACATAATGGAATTTAAAGGTAAAAGCAGGCGGTTATGGAATCGAAGCTGTGGAAAAGAATTAATAGAAACATAATGGAATTTAAAGCTTTCTTCGTCGATGATCTTCGTTGTCTTGATGAGAATTAATAGAAACATAATGGAATTTAAAGTAGTCTTAACTGCTCTGATCGCAGCTGCTTTCATCCGAATTAATAGAATCATATTGGAAAATGTTATATTGGAAATATAGATATGGTATAAAAGTTATTATTAGTTATATAGTAGGCTCAATCTGAATTAATACAAAAATAATGGAAGTCAAGAATAAATTTGGGGGATATTATAAAAAACATGAAATGAAAACAGAATTTTTATGGAAAATAATAGAATTTTATTGAAATTTAAAT

>NZ_LR699012|4|1|3066058-3066754|PILER-CR
GAATTAATAGAAACATAATGGAATTTAAAG	TCTATTGTCATTTTTCCGCAATACTCTTTCCAGTTC
GAATTAATAGAAACATAATGGAATTTAAAG	ACAATCAGGCGTAATCATTTCCAGTAACTCAATAGCA
GAATTAATAGAAACATAATGGAATTTAAAG	GAACTACAGACACTTTTTTCTATTATTGGTTATAAT
GAATTAATAGAAACATAATGGAATTTAAAG	ATCGTTGTAGTTAACGTATTAGATCCGGCAAAACAC
GAATTAATAGAAACATAATGGAATTTAAAG	CAGGCTGTAAGTGATAAAGCCATAACTGCGGCTAATCC
GAATTAATAGAAACATAATGGAATTTAAAG	TTGTTCAAACTCCTTTCTTTCTTCCTCGTCTTCATCAT
GAATTAATAGAAACATAATGGAATTTAAAG	TATATTCTTCTATGAAAGTATTATCATCACTGAAAA
GAATTAATAGAAACATAATGGAATTTAAAG	CAAAAAGCACAAATAAATACACGGTATACACAGTAAAT
GAATTAATAGAAACATAATGGAATTTAAAG	GTAAAAGCAGGCGGTTATGGAATCGAAGCTGTGGAAAA
GAATTAATAGAAACATAATGGAATTTAAAG	CTTTCTTCGTCGATGATCTTCGTTGTCTTGATGA
GAATTAATAGAAACATAATGGAATTTAAAG

>NZ_LR699012|4|4|3066058-3066991|CRISPRCasFinder
GAATTAATAGAAACATAATGGAATTTAAAG	TCTATTGTCATTTTTCCGCAATACTCTTTCCAGTTC
GAATTAATAGAAACATAATGGAATTTAAAG	ACAATCAGGCGTAATCATTTCCAGTAACTCAATAGCA
GAATTAATAGAAACATAATGGAATTTAAAG	GAACTACAGACACTTTTTTCTATTATTGGTTATAAT
GAATTAATAGAAACATAATGGAATTTAAAG	ATCGTTGTAGTTAACGTATTAGATCCGGCAAAACAC
GAATTAATAGAAACATAATGGAATTTAAAG	CAGGCTGTAAGTGATAAAGCCATAACTGCGGCTAATCC
GAATTAATAGAAACATAATGGAATTTAAAG	TTGTTCAAACTCCTTTCTTTCTTCCTCGTCTTCATCAT
GAATTAATAGAAACATAATGGAATTTAAAG	TATATTCTTCTATGAAAGTATTATCATCACTGAAAA
GAATTAATAGAAACATAATGGAATTTAAAG	CAAAAAGCACAAATAAATACACGGTATACACAGTAAAT
GAATTAATAGAAACATAATGGAATTTAAAG	GTAAAAGCAGGCGGTTATGGAATCGAAGCTGTGGAAAA
GAATTAATAGAAACATAATGGAATTTAAAG	CTTTCTTCGTCGATGATCTTCGTTGTCTTGATGA
GAATTAATAGAAACATAATGGAATTTAAAG	TAGTCTTAACTGCTCTGATCGCAGCTGCTTTCATCC
GAATTAATAGAATCATATTGGAAAATGTTA	TATTGGAAATATAGATATGGTATAAAAGTTATTATTAGTTATATAGTAGGCTCAATCT
GAATTAATACAAAAATAATGGAAGTCAAGA	ATAAATTTGGGGGATATTATAAAAAACATGAAATGAAAACAGAATTTTTATGG
AAAATAATAGAATTTTATTGAAATTTAAAT

>NZ_LR699012|4|1|3066058-3066820|CRT
GAATTAATAGAAACATAATGGAATTTAAAG	TCTATTGTCATTTTTCCGCAATACTCTTTCCAGTTC
GAATTAATAGAAACATAATGGAATTTAAAG	ACAATCAGGCGTAATCATTTCCAGTAACTCAATAGCA
GAATTAATAGAAACATAATGGAATTTAAAG	GAACTACAGACACTTTTTTCTATTATTGGTTATAAT
GAATTAATAGAAACATAATGGAATTTAAAG	ATCGTTGTAGTTAACGTATTAGATCCGGCAAAACAC
GAATTAATAGAAACATAATGGAATTTAAAG	CAGGCTGTAAGTGATAAAGCCATAACTGCGGCTAATCC
GAATTAATAGAAACATAATGGAATTTAAAG	TTGTTCAAACTCCTTTCTTTCTTCCTCGTCTTCATCAT
GAATTAATAGAAACATAATGGAATTTAAAG	TATATTCTTCTATGAAAGTATTATCATCACTGAAAA
GAATTAATAGAAACATAATGGAATTTAAAG	CAAAAAGCACAAATAAATACACGGTATACACAGTAAAT
GAATTAATAGAAACATAATGGAATTTAAAG	GTAAAAGCAGGCGGTTATGGAATCGAAGCTGTGGAAAA
GAATTAATAGAAACATAATGGAATTTAAAG	CTTTCTTCGTCGATGATCTTCGTTGTCTTGATGA
GAATTAATAGAAACATAATGGAATTTAAAG	TAGTCTTAACTGCTCTGATCGCAGCTGCTTTCATCC
GAATTAATAGAATCATATTGGAAAATGTTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LR699012.1\|WP_077327518.1\|3070240_3071347_+\|CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|274218
NZ_LR699012.1\|WP_077327503.1\|3062884_3063424_+\|stage-III-sporulation-protein-AG	unknown	unknown	gnl\|CDD\|274319
NZ_LR699012.1\|WP_077327524.1\|3073673_3074174_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NZ_LR699012.1\|WP_077327528.1\|3074187_3075180_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NZ_LR699012.1\|WP_077327891.1\|3059106_3060144_+\|stage-III-sporulation-protein-AA	unknown	unknown	gnl\|CDD\|274324
NZ_LR699012.1\|WP_077327515.1\|3069332_3070217_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|274215
NZ_LR699012.1\|WP_077325675.1\|3076371_3078021_-\|IS66-family-transposase	unknown	unknown	gnl\|CDD\|376980
NZ_LR699012.1\|WP_077327506.1\|3063426_3064002_+\|SpoIIIAH-like-family-protein	unknown	unknown	gnl\|CDD\|378918
NZ_LR699012.1\|WP_008391038.1\|3060695_3060893_+\|stage-III-sporulation-protein-AC	unknown	unknown	gnl\|CDD\|131895
NZ_LR699012.1\|WP_172622410.1\|3064694_3065900_+\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|307151
NZ_LR699012.1\|WP_044923843.1\|3062433_3062877_+\|stage-III-sporulation-protein-AF	unknown	unknown	gnl\|CDD\|378212
NZ_LR699012.1\|WP_055160285.1\|3060914_3061304_+\|stage-III-sporulation-protein-AD	unknown	unknown	gnl\|CDD\|131896
NZ_LR699012.1\|WP_077327509.1\|3067195_3067948_+\|hypothetical-protein	cas6	pfam01881_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
NZ_LR699012.1\|WP_077327512.1\|3067948_3069340_+\|type-I-CRISPR-associated-protein-Cas8a1/Csx8	cas8b2	cd09697_cas8b2_CAS-I-B	gnl\|CDD\|187875
NZ_LR699012.1\|WP_077327534.1\|3075581_3075767_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239330
NZ_LR699012.1\|WP_009264835.1\|3060140_3060659_+\|stage-III-sporulation-protein-AB	unknown	unknown	gnl\|CDD\|378204
NZ_LR699012.1\|WP_077327521.1\|3071403_3073662_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_LR699012.1\|WP_077327531.1\|3075182_3075461_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NZ_LR699012.1\|WP_055160288.1\|3061300_3062428_+\|stage-III-sporulation-protein-AE	unknown	unknown	gnl\|CDD\|378202
NZ_LR699012.1\|WP_077327500.1\|3057164_3059144_+\|DNA-topoisomerase-III	unknown	unknown	gnl\|CDD\|236078

Protein	Function_ID	Function_description	E-value
NZ_LR699012.1\|WP_077327518.1\|3070240_3071347_+\|CRISPR-associated-protein-Cas5	gnl\|CDD\|274218	TIGR02593, CRISPR-associated_protein_Cas5, CRISPR-associated protein Cas5, N-terminal domain. This model represents a shared N-terminal domain, about 43 amino acids in length, common to a number of related protein families each of which is associated with a distinct subtype of CRISPR/cas system, where CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeat and Cas is an abbreviation for CRISPR-associated. Members of this family are widely distributed enough that we designated the family Cas5. Homology appears remote, or absent, between the more C-terminal regions different subfamilies of these proteins, which typically are 210 to 265 amino acids in total length. Cas5 proteins of six different CRISPR/cas subtypes so far defined are described by respective full-length models TIGR01868, TIGR01876, TIGR01895, TIGR01874, TIGR02586, and TIGR02592. The best characterized protein in this family is DevS or Myxococcus xanthus, a Cas protein that appears to participate in a species-specific developmental pathway.	4.09417e-12
NZ_LR699012.1\|WP_077327503.1\|3062884_3063424_+\|stage-III-sporulation-protein-AG	gnl\|CDD\|274319	TIGR02830, Stage_III_sporulation_protein_AG, stage III sporulation protein AG. CC A comparative genome analysis of all sequenced genomes of shows a number of proteins conserved strictly among the endospore-forming subset of the Firmicutes. This protein, a member of this panel, is found in a spore formation operon and is designated stage III sporulation protein AG. [Cellular processes, Sporulation and germination].	6.04316e-21
NZ_LR699012.1\|WP_077327524.1\|3073673_3074174_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	1.5335e-54
NZ_LR699012.1\|WP_077327528.1\|3074187_3075180_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	6.25224e-162
NZ_LR699012.1\|WP_077327891.1\|3059106_3060144_+\|stage-III-sporulation-protein-AA	gnl\|CDD\|274324	TIGR02858, Stage_III_sporulation_protein_AA, stage III sporulation protein AA. Members of this protein are the stage III sporulation protein AA, encoded by one of several genes in the spoIIIA locus. It seems that this protein is found in a species if and only if that species is capable of endospore formation. [Cellular processes, Sporulation and germination].	8.1882e-102
NZ_LR699012.1\|WP_077327515.1\|3069332_3070217_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|274215	TIGR02585, conserved_protein, CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This clade is a member of the DevR family (TIGR01875) and includes the DevR protein of Myxococcus xanthus, a protein whose expression appears to be regulated through a number of means, including both location and autorepression; DevR mutants are incapable of fruiting body development.	1.81366e-54
NZ_LR699012.1\|WP_077325675.1\|3076371_3078021_-\|IS66-family-transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	7.80787e-88
NZ_LR699012.1\|WP_077327506.1\|3063426_3064002_+\|SpoIIIAH-like-family-protein	gnl\|CDD\|378918	pfam12685, SpoIIIAH, SpoIIIAH-like protein. Stage III sporulation protein AH (SpoIIIAH) is a protein that is involved in forespore engulfment. It forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the mother cell end. This allows sigma-E-directed gene expression in the mother-cell compartment of the sporangium to trigger the activation of sigma-G forespore-specific gene expression by a pathway of intercellular signaling. This family of proteins is found in bacteria, archaea and eukaryotes and so must have a wider function that in sporulation. Proteins in this family are typically between 174 and 223 amino acids in length.	1.94946e-42
NZ_LR699012.1\|WP_008391038.1\|3060695_3060893_+\|stage-III-sporulation-protein-AC	gnl\|CDD\|131895	TIGR02848, Stage_III_sporulation_protein_AC, stage III sporulation protein AC. Members of this protein family are designated SpoIIIAC, part of the spoIIIA operon of sporulation genes whose mutant phenotype is linked to sporulation stage III. Members of this family are encoded by the genome of a species if and only if that species is capable of endospore formation, as in Bacillus subtilis. The molecular function of this small, probable integral membrane protein is unknown. [Cellular processes, Sporulation and germination].	3.9159e-13
NZ_LR699012.1\|WP_172622410.1\|3064694_3065900_+\|IS256-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	3.92443e-128
NZ_LR699012.1\|WP_044923843.1\|3062433_3062877_+\|stage-III-sporulation-protein-AF	gnl\|CDD\|378212	pfam09581, Spore_III_AF, Stage III sporulation protein AF (Spore_III_AF). This family represents the stage III sporulation protein AF (Spore_III_AF) of the bacterial endospore formation program, which exists in some but not all members of the Firmicutes (formerly called low-GC Gram-positives). The C-terminal region of these proteins is poorly conserved.	9.06436e-09
NZ_LR699012.1\|WP_055160285.1\|3060914_3061304_+\|stage-III-sporulation-protein-AD	gnl\|CDD\|131896	TIGR02849, Stage_III_sporulation_protein_AD, stage III sporulation protein AD. Members of this family are the uncharacterized protein SpoIIIAD, part of the spoIIIA operon that acts at sporulation stage III as part of a cascade of events leading to endospore formation. Note that the start sites of members of this family as annotated tend to be variable; quite a few members have apparent homologous protein-coding regions continuing upstream of the first available start codon. The length of the alignment and the scoring cutoff thresholds for the model have been set to try to detect all valid members of the family, even if annotation of the start site begins too far downstream. [Cellular processes, Sporulation and germination].	1.23829e-14
NZ_LR699012.1\|WP_077327509.1\|3067195_3067948_+\|hypothetical-protein	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.14014e-09
NZ_LR699012.1\|WP_077327512.1\|3067948_3069340_+\|type-I-CRISPR-associated-protein-Cas8a1/Csx8	gnl\|CDD\|187875	cd09744, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as Csx8 family.	3.49669e-128
NZ_LR699012.1\|WP_077327534.1\|3075581_3075767_+\|hypothetical-protein	gnl\|CDD\|239330	cd03032, ArsC_Spx, Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex formation between RNAP and certain transcriptional activator proteins like ResD and ComA. In response to oxidative stress, Spx can also activate transcription, making it a general regulator that exerts both positive and negative control over transcription initiation. Spx has been shown to exert redox-sensitive transcriptional control over genes like trxA (TRX) and trxB (TRX reductase), genes that function in thiol homeostasis. This redox-sensitive activity is dependent on the presence of a CXXC motif, present in some members of the Spx subfamily, that acts as a thiol/disulfide switch. Spx has also been shown to repress genes in a sulfate-dependent manner independent of the presence of the CXXC motif.	0.004539
NZ_LR699012.1\|WP_009264835.1\|3060140_3060659_+\|stage-III-sporulation-protein-AB	gnl\|CDD\|378204	pfam09548, Spore_III_AB, Stage III sporulation protein AB (spore_III_AB). SpoIIIAB represents the stage III sporulation protein AB, which is encoded in a spore formation operon: spoIIIAABCDEFGH that is under sigma G regulation. A comparative genome analysis of all sequenced genomes of Firmicutes shows that the proteins are strictly conserved among the sub-set of endospore-forming species.	1.19548e-49
NZ_LR699012.1\|WP_077327521.1\|3071403_3073662_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.51689e-61
NZ_LR699012.1\|WP_077327531.1\|3075182_3075461_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.76684e-28
NZ_LR699012.1\|WP_055160288.1\|3061300_3062428_+\|stage-III-sporulation-protein-AE	gnl\|CDD\|378202	pfam09546, Spore_III_AE, Stage III sporulation protein AE (spore_III_AE). This represents the stage III sporulation protein AE, which is encoded in a spore formation operon spoIIIAABCDEFGH under the control of sigma G. A comparative genome analysis of all sequenced genomes of Firmicutes shows that the proteins are strictly conserved among the sub-set of endospore-forming species.	4.88504e-83
NZ_LR699012.1\|WP_077327500.1\|3057164_3059144_+\|DNA-topoisomerase-III	gnl\|CDD\|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0

>NZ_LR699012.1|WP_172622410.1|3064694_3065900_+|IS256-family-transposase
MQGYLKDNDISVKNGTDVNAIMRDMMSVILEGALDEELNEELGYSRYDYRNKDTNNSRNGHSGKTMHTSYGDMEIAVPRDRNGEYEPRLIKKYQNTVTQDMEEKILSMYAKGMTTGDIESHMKELYDIDISDSTISRITDKILPIVKEWQERPLEEVYAVVYMDAIHYHVRSEGRIVKRAVYIALGVNMDGKKEVLGMYVGDNESAKFWLSIINGLKNRGVEDILITCVDGLTGFPQAIEAVFPQTEIQQCIIHQIRNTTRYVSYKDNRKVMADLKAVYAAPTEEIALENLEDFGEKWNSKYPKIYKSWSERWATLATYFKYPEQVRKLIYTTNAIEGFNRQLRKVTKSKTVFPTDDSLLKMLYLATMDITKKWTGRRRDWSQIRAQLDIFFEERLEKYMY
>NZ_LR699012.1|WP_077327506.1|3063426_3064002_+|SpoIIIAH-like-family-protein
MKKVFQKNQMIIMTLAVVIAVAGYVNYSQKYDPTGTKNSKTKTVSKNVAKESAAAVTDDVTDVGEAVLTNAQVSNYVAKAKLEREQTHSKAKDTLEEIIKDQTVKDSVKQDAVDKLAMLSEQMEMETAAENLLGAKGFLNSIVTITNGKVDVLVNKKDLSKVERSQIEDIVVRKVGCQLGDVVISSIKTEE
>NZ_LR699012.1|WP_077327503.1|3062884_3063424_+|stage-III-sporulation-protein-AG
MIEREKLQHLIENIGIPKLCLILLLGISLIIVSIPSGKTKKNAQSTETTAKEDSTDLYVKKQERRLVNALKHVEGVGKVKVMITVNSSKEAVVNKDSPYEQSSSEKEKTVKEDEQTILVEEDGKKVPYVIKEVEPVVEGVVVVAQGGGNDIIKNQIVEAVSVLFHISSYKVKVLKMEDS
>NZ_LR699012.1|WP_044923843.1|3062433_3062877_+|stage-III-sporulation-protein-AF
MDYLKMIIFFLILTTLIDQLCDKSIYRPYLRLMTGFMLISLMMQPISYYLSNEDIVTQAISTAVKGENNPAFLDGAKEEKQNQIKEQITTLFSQYDLKVLDVDSKVNEKGTIEKIDIKTDKLRHTKKLKTAISNFYNMKESNINISE
>NZ_LR699012.1|WP_055160288.1|3061300_3062428_+|stage-III-sporulation-protein-AE
MKQRIFLLTLLFLLILTRTNDISAKETKLNEDMFTNVENTLKDKEIDLSYTQLVKQLIHGNVKGVLHTIKAKMKEGFLNRMLIQKDLIREILLIAFTAAIFKNLSDSFFQQSTANSAFYITYVILCGVMVHSFFYLNKTVTQLVTLMADYMKGMIMAYSLAVVSTSGITTSTTVYEFYLLLIYAMTTLTNVVLLPMIKILFVLKIINHISKEEHFSRLCKTLEGVIKFLLKGFLSVLLGVQLIQSMILPAVDSMKNTVLQKGMSAIPGIGSGLNSAMTMVIGSAVVIKNSIGAVGILVLIVIIVPPVIEITAVVLTYLLAGIMIQPISDKRITGAMDAVIQSGKLMLSMIFTMALLFILSVALIAFSTNVNYYAG
>NZ_LR699012.1|WP_055160285.1|3060914_3061304_+|stage-III-sporulation-protein-AD
MIKVAVFGIVASLIAMKIKTIRPEIAVVIAVISSILLAMYGLKQMEEILTVFDMIRSYSKIPQSYFQILLKLIGISFICEFASNICKDAGQASIAKQIEFAGKLAILIVGLPVFESLLGTIQKLLGNGT
>NZ_LR699012.1|WP_008391038.1|3060695_3060893_+|stage-III-sporulation-protein-AC
MSVNIIFRIAAVGILVTILVQVLKHSGRDEQAFLITLAGLILVLGWVIPYIYDLFESVQTLFTIS
>NZ_LR699012.1|WP_009264835.1|3060140_3060659_+|stage-III-sporulation-protein-AB
MIKILGSLIVIFAGIGFGFHKAAKEQKRLEQGIAIKRMLYLLQGEIRYGFTPLPEAVLKISTKTEKEYQPFLKKVAKQLETHSEESFAKVWQQTAEQKLKQVIYEPKFYEILKNMGETIGYLDQQMQEKTILLTIEQLDDQIFLMKDQVVKNCKMYRSLGISLSVLIVIILL
>NZ_LR699012.1|WP_077327891.1|3059106_3060144_+|stage-III-sporulation-protein-AA
MTRSHHIIRRKNKITFIKTPSITYIWIIPKWGGVFKFMKEEEILGILPLHIRTIIKQAGINWDELQEIRLRIQKPVILKYNAKTCYLSEQGKITTRKEQLHIVTSQEIRQAMEYISSYSMYAYIEQLKQGFLTIRGGHRVGICGTVVMDHDKVKTIRHISGLNIRVAHEVKGCADTLYSRCTRMGKLIPTLIISPPGCGKTTLLRDMIRKISDEGQTVGVVDERSEIGACYQGVAQNDLGIQTDVMDACEKGQGMNMLIRSMAPDVIAVDEIGSKEDVEALFFCAYRGCSILATTHGKNKESLSKNPYMREIINKKMFQRYVILEQRNQPGYIAQIIDENGVVLN
>NZ_LR699012.1|WP_077327500.1|3057164_3059144_+|DNA-topoisomerase-III
MKALFITEKPSVAREFAAALNINAKNRDGYMEGDKAVITWCVGHLVTMSYPDQYDPALKKWDLETIPFIPDTFKYETIPGVQKQFDIVSSLLNREDIDTIYVCTDSGREGEYIYRLVDQQANVSKDKKKKRVWIDSQTKEEVIRGVKEAKDLSEYDNLAAAAYLRAKEDYLMGINFSRVLTLKYGWTLGNYLNQKRSLVVAVGRVMTCVLGMIVKREREIRTFVPTPFYRILGHFDCQGFEVEAEWKAVKGSKYFESKKLYKDNGFLDKNDAKEFIKYLEDGSNNETIVVSSSKRQEKKNPPLLYNLAELQNECSKRFKLSPDETLKVVQDLYEKKLVTYPRTDARVLSSAVAKEIYKNIGGLNNYTPLSGFANEIMQGKKYQGIIKSKYVDDKKITDHYAIIPTGQAVGSLSRISEMGQKVYDVIARRFLSIFMPPAVYLKIKLETQTKGEAFFANFKMLKDPGYLKVTGMGGQKKEAQLTEEQIHAISSLKKGMPLPVKDYTIKDGTTSAPKRYNSGSLILAMENAGQLIEDEDLREQIKGSGIGTSATRAEIVKKLVSNKYIALNKKTQIVTPTLTGEMIVNVVSASIGSLLNPTLTASWEKGLTYVAEGSVTEEEYMQKLDKFVTQKTNIVKQNNFQYQLRQSFDQIAPYYQKKK
>NZ_LR699012.1|WP_077327509.1|3067195_3067948_+|hypothetical-protein
MRLELQMELLKPEIDIDYRRIIISYLKFALEHCEGGRFFEKFYKNRDNIVKDYCFSTVFSKPRFTKEKIYFDKNEMKIIFSCSDRNRTGLIFQTAFLSIQHMEFPLANGNHMILRKIIQKKEVLITEPVVYFQTMLGNGLCVREHNRETNRDTFITCEDKEFSEKTELIIKNQLQMAGFYKKQYEDIKVEPVDCKKIVVKHYGIFIDLTVGILKISGDMDALQYLYQSGAGSHHATGFGSLNVIRQGGGR
>NZ_LR699012.1|WP_077327512.1|3067948_3069340_+|type-I-CRISPR-associated-protein-Cas8a1/Csx8
MKDEMVCLEPFDWRYSAAIVGLRKYLEWLGVDEEPNLIITEDTLEYNKKYLDKEDFLKFAEYYFKDDMHHIEIENKLKEKNPTEDQINIVNEKMKANTILKNKFKKIKFDGHNQDEIQNIIDQNREEIICETFRNKNNLYKNYCNPNQLFKDKQECCRLNGYYIDMPKKGKSISYAFDKSNYVGNDIPEFDFIPFAFSGCREKFFINDNVDLNRLQKTNNQWTRTVKSQMEEAKQKNERVNTKRIFIDCLIEAKDFLQSDIEIIVKKPERAYFETLYLRKESLEILKNMKSYYKAFCFSIKISDDYWINILNEVFDAVVNFTLLDDLINKLLKDSREEGNSYVISKLLKVNVEIKKGDEKMKNTMKAAFACAKQIVDKKDGNKPRVSDTKLKSYCTKLINAIILDDYDQFQKILINLSNYAEVPCGFAYDLFEDFEGNKEIAYTFVNSLNRYKNNNQEGKDNE
>NZ_LR699012.1|WP_077327515.1|3069332_3070217_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MNKKALTLTVVANMTSNYSEGLGNVASVQKVFKNRRIYSMRSRESLKNAIMIQSGWYDDLETEVDGATQKKVNEDLNAINCRALEGGYMNTQATTYVRRSSFYVTDAISTEHFISEPRFHNNLYMATNYAKSKGLSVQEPGKNNIGLMPYQYEYDKSLKIYSITIDLEMIGKDENFEGEADAKEKADRVICLLYAIENLSLVVKGNLDNAEPIFAVGGLSPRKTHYFENVVNVEEAKLIISSDLKNKIDRGFYAGLLQGNLLENEEEIEEELHPLTITEMFDKLRQEVKEYYLG
>NZ_LR699012.1|WP_077327518.1|3070240_3071347_+|CRISPR-associated-protein-Cas5
MKALRIKLHQTSANYRKEETIDNKMTYPLPPISTVTGALHSICGYTEYHKMLVSIQGNYQSMQNKIYTHHCFLNSTMDDRGLLVKMKNENLLSTAYDKVAEAKKSQGNSFLKGITIQVYNQGLLDEYRNLKEMGNKIALWKKSEEYTDKVAMYKTKKQQLTKQKKTLDKKSTEYTDFVEKEKELKQEEKDWKNKIKEYEETHYKKPIAKFRSLTKSVKKYEILNNITLILHIQAEESVLQDIMENIYDLKSLGRSEDFVDVEEIKLVDLVEPEEEIISSYSAYVNYRDTKPINNVGDGNIIVLTSEGIQGTKYYMGTEYKKEKGKRIFLQDKKVPVVYVSNHSVDEESKNVWIDNAGDEQYIVNFLQK
>NZ_LR699012.1|WP_077327521.1|3071403_3073662_+|CRISPR-associated-helicase/endonuclease-Cas3
MIKDLYDYLAKPDKTIGEHVEDLIFRANILRKLGYIKDIHIYNLLIQACKGHDLGKANKEFLKRILNPKLHFDETKEISHNILSVYYLDKNEFDENTDDYLIVACCILFHHDYCNEPLVIKTRTSQINSLLIPEYNQKPSRRMLKNICNNYLKKQETIIVKGLLHRCDYSASGNYEIEYPNDFLEAGLAQMMNEWQKKKKDSCWNELQEFCIENREENIIALAPTGMGKTEAGLLWIGNHKGFFILPIRTAINAIYDRIKNQILKDEKLEERLGLLHSESLSYYGNHVGQEMDILDYRNRGQALSLPLNISTLDQLFDFVFKYKGYEMKLATLAYSKIVIDEIQMYDAEMLAYLIYGLRRIHELGGEIAIVTATLPPFIKKLLRDKNIGNIEFKECDFTNDLKRHSVKVIDESICEDDIIQCYNQNIKEGKGNKILVVCNTIKKAQKMYDQIKEKNETLNSHVLHSRFDREDRKNLENEIKEFGKTYNEQNEIDIQNGIWIATSIVEVSLDIDFDYLFTELTDLNGLFQRMGRCNRKGVKQLDGYNCFVYCDGSDIKQGQKGFLDSVFYEQSKKALKTVDGILEESQKTKLINDYFTYDDIRSSDYMRQFKDTFDWISELDIGDFEKDEIKMRNIFTKSIVPKIVYDQNKDEIVLLEERQTLISKKLKDSNIEQKERENLFRERIEIQERLRDFIVQIPYYEYHKYYKKVYQTYGTVNISKYEHIDIMNCQYDIKGFYPLNYENIGEDAMMF
>NZ_LR699012.1|WP_077327524.1|3073673_3074174_+|CRISPR-associated-protein-Cas4
MEERITGVMIYYYFVCKRKLWYFCHDLQMENVSQNENVQLGKLLDETSYRRNQKHINIDDTINIDFIKDFQEIHEVKKSKSIEEAGIWQVKYYLYYLKKKGVDISKAQIDYPLLKKNIEVSLSEEDEKQMKNIIDHIIQIRKQAIPELDDSKKICKKCAYYDICFI
>NZ_LR699012.1|WP_077327528.1|3074187_3075180_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MKKSLYIYNCGDLKRKDNTLRFTTYDDEKRDVPIERISDIYVMSELSFNTKFINFISQYGIPMHFFNYYHFYTGSYYPRESLLSGELLVKQVEHYIDKEKRIVIARKFIEAAAENIYRNLRYYNSRGKDVTEHMRYIEGLKKKIPNAQEIDQLMGIEGNIRKKYYEAWSVIINQEIEFEKRVMHPPDNMINSLISFVNSLIYSKTLTEIYHTQLNPTISYLHEPGSRRYSLCLDLSEIFKPLIGDRLIFSLLNKNQITENSFTRELNFLHLKKEASQLIVNELEKKLQATIMHKDLHRKVSYQYLIRLEAYKLIKHLIEEKEYEGFKMWW
>NZ_LR699012.1|WP_077327531.1|3075182_3075461_+|CRISPR-associated-endonuclease-Cas2
MYVVLVYDISQEKNGAKRWSKVFKISKKYLSHIQNSVFEGEISKPQLAQLQQEMKPYIDTELDSVIIFKSRQEKWLDKEFWGKKEDKTSFFL
>NZ_LR699012.1|WP_077327534.1|3075581_3075767_+|hypothetical-protein
MNIEAFNTDTLRKLVRNLQDENKKLKEKLDEANIPYEEINLFEQPINKSAEYDPDQGIMAS
>NZ_LR699012.1|WP_077325675.1|3076371_3078021_-|IS66-family-transposase
MSSGRNDIRLIELKDTISQLNQTIRVQTEMIKDLRKAIEEHHASDEKKDQIISNLQAEISYLKAKLFGASSEKRRKEDLPGQMSLFDELMEEEPAKEIEPEYIEIKAHERKRKKKPDLNEQFRDIPVRQEFVDTLTEEQKTCSICGTKMVEIGHELIRSEVIFTPAKLERVEYIATTYGCPKCKETEEPQFVKDNGIPALLRGSYVSPSLAAHVICQKFMNAMPLYRQEKDWEQLGATITRASMARWIIHCSKTYFQPMYEYFEKQLKKRKFLMMDETRLQVLKEEGRRAQTQSFIWVVRSGEDGLPKIVLYHYTETRAGKHAVGFLDGIKPGYYFMADGYHGYNLLKDGKRCCCYAHIRRYLLEAIPKGHEKDYTDPAVQGVLYCDKLFEYERRYREKGFSPEQRKKRRLKDEKPVIEAFLSWLDAQTPVKGSRLDKAVIYIRNRKDSLMTYLEDGRCSLSNNLSENAIRPITVGRKNWLFCDSVDGANASAICFTMIEMAKAYDLNVYKYLNFLLEKRPNARTAQKELEKLAPWNEEVQKMFARKMK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LR699012_4	4.10\|3066691\|34\|NZ_LR699012\|PILER-CR,CRISPRCasFinder,CRT	3066691-3066724	34	NZ_CP030828	Neorhizobium sp. NCHU2750 plasmid pNCHU2750a, complete sequence	713066-713099	10	0.706

1. spacer 4.10|3066691|34|NZ_LR699012|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030828 (Neorhizobium sp. NCHU2750 plasmid pNCHU2750a, complete sequence) position: , mismatch: 10, identity: 0.706

ctttcttcgtcgatgatcttcgttgtcttgatga	CRISPR spacer
tcacgttcctcgatgatcttcgtcgtcttggcgg	Protospacer
.. . *** **************.******..*.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

269505 : 305276

Clostridium_phage(43.75%)

holin,transposase,coat,tail,portal,terminase,integrase,tRNA

attL 282989:283008|attR 285315:285334

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008393634.1\|269505_270225_-\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_008393633.1\|270217_270733_-	16S rRNA processing protein RimM	NA	NA	NA	NA
WP_009265056.1\|271233_272685_-	aminoacyl-histidine dipeptidase	NA	NA	NA	NA
WP_008393630.1\|272697_273042_-	hypothetical protein	NA	NA	NA	NA
WP_008393628.1\|273071_273407_-	PqqD family protein	NA	NA	NA	NA
WP_077325251.1\|273487_275425_-	oligopeptide transporter, OPT family	NA	NA	NA	NA
WP_008393626.1\|275587_276499_-	hypothetical protein	NA	NA	NA	NA
WP_158520172.1\|277386_277659_-\|transposase	transposase	NA	NA	NA	NA
WP_077325253.1\|278384_279167_+	hypothetical protein	NA	NA	NA	NA
WP_077325255.1\|279700_281383_-	glycogen/starch synthase	NA	NA	NA	NA
WP_077325257.1\|281583_282132_-	N-acetylmuramoyl-L-alanine amidase	Q8W5Y8	Listeria_phage	4.2e-19	37.1
WP_077325259.1\|282131_282593_-\|holin	phage holin family protein	NA	NA	NA	NA
WP_077325261.1\|282689_282965_-	hypothetical protein	NA	NA	NA	NA
282989:283008	attL	NA	NA	NA	NA
WP_015530861.1\|283323_283566_-	hypothetical protein	NA	NA	NA	NA
WP_077325263.1\|283761_284757_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_077325265.1\|285058_285439_-	hypothetical protein	NA	NA	NA	NA
285315:285334	attR	NA	NA	NA	NA
WP_077325267.1\|285455_285686_-	hypothetical protein	NA	NA	NA	NA
WP_077325269.1\|285700_286333_-	hypothetical protein	A0A0A7S1G0	Clostridium_phage	1.3e-06	32.9
WP_077325271.1\|286344_287562_-\|tail	phage tail protein	A0A1S5S9Z5	Streptococcus_phage	2.5e-19	24.2
WP_077325274.1\|287562_288276_-	mtfA protein	NA	NA	NA	NA
WP_077325276.1\|288277_293716_-\|tail	phage tail tape measure protein	A0A0A7S163	Clostridium_phage	1.1e-85	57.0
WP_077325278.1\|293819_294470_-	hypothetical protein	A0A0A8WII3	Clostridium_phage	3.5e-28	34.2
WP_077325280.1\|294466_294817_-	hypothetical protein	NA	NA	NA	NA
WP_077325282.1\|294863_295370_-	hypothetical protein	A0A0A8WJB7	Clostridium_phage	6.0e-28	45.1
WP_077325284.1\|295371_295809_-	hypothetical protein	NA	NA	NA	NA
WP_077325286.1\|295805_296135_-	hypothetical protein	A0A0A8WIK8	Clostridium_phage	4.8e-26	50.4
WP_077325288.1\|296137_296548_-	hypothetical protein	NA	NA	NA	NA
WP_077325290.1\|296516_296924_-	hypothetical protein	A0A1J1JB19	Escherichia_phage	2.5e-08	34.5
WP_077325292.1\|296937_298065_-\|coat	phage coat protein	A0A0A7RTH8	Clostridium_phage	1.2e-137	67.9
WP_077325293.1\|298080_298677_-	phage scaffolding protein	Q9T1B8	Listeria_phage	1.9e-20	36.6
WP_077325295.1\|298945_299266_-	hypothetical protein	A0A2K9V3K4	Faecalibacterium_phage	1.2e-21	49.0
WP_077325297.1\|299258_299564_-	hypothetical protein	NA	NA	NA	NA
WP_077325299.1\|299560_301324_-	hypothetical protein	A0A2K9V3K1	Faecalibacterium_phage	3.9e-66	37.0
WP_077325301.1\|301334_302726_-\|portal	phage portal protein	F6K8Q7	Clostridium_phage	2.2e-136	53.6
WP_077325303.1\|302730_303996_-\|terminase	PBSX family phage terminase large subunit	A0A2H4J4X1	uncultured_Caudovirales_phage	7.2e-163	64.2
WP_099046223.1\|303980_304808_-\|terminase	terminase small subunit	E5DV49	Deep-sea_thermophilic_phage	2.3e-53	47.3
WP_077325307.1\|304985_305276_-	hypothetical protein	Q5ULN6	Lactobacillus_virus	5.3e-13	48.8

DBSCAN-SWA_2

309927 : 322205

Bacillus_phage(27.27%)

integrase,transposase

attL 311764:311777|attR 324086:324099

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_077325323.1\|309927_311013_-	hypothetical protein	A0A2H4JC51	uncultured_Caudovirales_phage	1.3e-152	68.2
WP_167543146.1\|311005_311164_-	hypothetical protein	NA	NA	NA	NA
WP_077325325.1\|311157_311691_-	hypothetical protein	NA	NA	NA	NA
WP_077325327.1\|311677_312040_-	hypothetical protein	NA	NA	NA	NA
311764:311777	attL	NA	NA	NA	NA
WP_077325329.1\|312052_312301_-\|transposase	transposase	NA	NA	NA	NA
WP_077325331.1\|312564_312783_-	hypothetical protein	NA	NA	NA	NA
WP_077325333.1\|313043_313364_-	hypothetical protein	U5J9F3	Bacillus_phage	2.2e-07	37.8
WP_077325335.1\|313369_314107_-	hypothetical protein	NA	NA	NA	NA
WP_077325337.1\|314111_314474_-	DUF1064 domain-containing protein	A8ASP7	Listeria_phage	1.7e-16	45.8
WP_077325339.1\|314400_315105_-	hypothetical protein	D7RWH3	Brochothrix_phage	1.2e-37	40.0
WP_077325341.1\|315104_315638_-	hypothetical protein	A0A0E3Y6D2	Fusobacterium_phage	2.8e-39	49.7
WP_077325343.1\|315647_316139_-	siphovirus Gp157 family protein	H9A0R4	Staphylococcus_phage	7.4e-31	44.8
WP_077325345.1\|316140_316458_-	hypothetical protein	NA	NA	NA	NA
WP_077325347.1\|316447_317005_-	hypothetical protein	NA	NA	NA	NA
WP_077325350.1\|317144_317537_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_077325352.1\|317745_318153_+	hypothetical protein	NA	NA	NA	NA
WP_077325354.1\|318127_318418_-	hypothetical protein	NA	NA	NA	NA
WP_055257911.1\|318460_318685_-	helix-turn-helix transcriptional regulator	Q38329	Lactococcus_phage	4.9e-06	43.8
WP_055257768.1\|318839_319280_+	helix-turn-helix transcriptional regulator	D2XR39	Bacillus_phage	2.1e-21	42.0
WP_077325356.1\|319354_319714_+	ImmA/IrrE family metallo-endopeptidase	Q0H245	Geobacillus_phage	2.3e-21	43.7
WP_158520173.1\|319729_320635_+	InlB B-repeat-containing protein	U5J9H5	Bacillus_phage	2.0e-10	46.9
WP_077325360.1\|321179_322205_+\|integrase	tyrosine-type recombinase/integrase	H7BVF7	unidentified_phage	6.3e-117	61.3
324086:324099	attR	NA	NA	NA	NA

DBSCAN-SWA_3

485017 : 534638

Clostridium_phage(25.0%)

holin,tRNA,tail,portal,head,terminase,protease,integrase,capsid,plate

attL 485004:485019|attR 521700:521715

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
485004:485019	attL	NA	NA	NA	NA
WP_077325476.1\|485017_485524_-	N-acetylmuramoyl-L-alanine amidase	A0A0B5D123	Listeria_phage	2.5e-13	32.9
WP_055160857.1\|485513_485957_-\|holin	phage holin family protein	A0A090D848	Clostridium_phage	1.3e-29	49.3
WP_167543149.1\|486030_486198_-	hypothetical protein	NA	NA	NA	NA
WP_055160833.1\|486197_486482_-	hypothetical protein	NA	NA	NA	NA
WP_055160830.1\|486478_486802_-	Ig-like domain-containing protein	NA	NA	NA	NA
WP_077325478.1\|486811_487723_-	hypothetical protein	H7BV37	unidentified_phage	3.7e-84	59.1
WP_077325480.1\|488019_488424_-	hypothetical protein	NA	NA	NA	NA
WP_077325482.1\|488425_488962_-	DUF2313 domain-containing protein	A0A0A8WFE8	Clostridium_phage	1.6e-15	32.4
WP_158520175.1\|488952_490011_-\|plate	baseplate J/gp47 family protein	H7BWD5	unidentified_phage	6.6e-69	41.6
WP_077325486.1\|490003_490435_-	DUF2634 domain-containing protein	NA	NA	NA	NA
WP_077325488.1\|490413_490650_-	hypothetical protein	NA	NA	NA	NA
WP_077325490.1\|490649_492380_-	C40 family peptidase	A0A0K2SUC1	Clostridium_phage	4.4e-86	38.0
WP_055160807.1\|492376_493057_-	LysM peptidoglycan-binding domain-containing protein	A0A0K2SUI2	Clostridium_phage	4.5e-26	43.8
WP_077325492.1\|493075_495223_-\|tail	phage tail tape measure protein	A0A0A7RUN0	Clostridium_phage	4.2e-94	43.9
WP_055160801.1\|495403_495802_-	hypothetical protein	NA	NA	NA	NA
WP_055160798.1\|495811_496213_-\|tail	phage tail tube protein	A0A0A7RVT1	Clostridium_phage	7.4e-29	49.6
WP_077325494.1\|496281_497286_-\|tail	phage tail sheath subtilisin-like domain-containing protein	A0A1V0DZX4	Clostridioides_phage	2.9e-58	41.0
WP_077325496.1\|497314_497773_-	hypothetical protein	NA	NA	NA	NA
WP_055160789.1\|497769_498228_-	hypothetical protein	NA	NA	NA	NA
WP_055160786.1\|498208_498568_-\|head	phage head closure protein	NA	NA	NA	NA
WP_055160783.1\|498564_498855_-\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_155512798.1\|498841_499003_-	hypothetical protein	NA	NA	NA	NA
WP_077327698.1\|499006_500212_-\|capsid	phage major capsid protein	U3PDR8	Lactobacillus_phage	8.9e-94	50.9
WP_070097641.1\|500241_500844_-\|head,protease	HK97 family phage prohead protease	NA	NA	NA	NA
WP_055160777.1\|500834_502061_-\|portal	phage portal protein	A0A075KK59	Lactobacillus_phage	1.7e-92	46.1
WP_055160775.1\|502073_503813_-\|terminase	terminase	F7V9A2	Lactobacillus_virus	4.5e-139	47.4
WP_077325498.1\|503802_504354_-	hypothetical protein	NA	NA	NA	NA
WP_055160770.1\|504480_504876_-	HNH endonuclease	A0A0D4DD69	Staphylococcus_phage	2.4e-08	36.8
WP_055160768.1\|505460_506009_-\|integrase	tyrosine-type recombinase/integrase	Q8SBK8	Clostridium_phage	5.9e-45	53.4
WP_055160766.1\|506135_506333_-	hypothetical protein	NA	NA	NA	NA
WP_055160764.1\|506878_507286_-	type II toxin-antitoxin system HicB family antitoxin	A0A1X9I5X0	Streptococcus_phage	1.2e-15	36.3
WP_055160761.1\|507376_507547_-	type II toxin-antitoxin system HicA family toxin	A0A0R6PGU2	Moraxella_phage	3.1e-05	50.0
WP_055160758.1\|507652_507844_-	hypothetical protein	NA	NA	NA	NA
WP_077325500.1\|508086_508533_-	sigma-70 family RNA polymerase sigma factor	A0A218MNE1	uncultured_virus	3.0e-07	31.6
WP_077325502.1\|508609_508897_-	hypothetical protein	NA	NA	NA	NA
WP_077325504.1\|508896_509763_-	hypothetical protein	A0A0S2MYA8	Enterococcus_phage	1.3e-33	54.1
WP_077325506.1\|509752_510874_-	ParB N-terminal domain-containing protein	H7BVD1	unidentified_phage	1.7e-14	29.9
WP_077325508.1\|510874_511591_-	AAA family ATPase	E9LUK9	Lactobacillus_phage	4.4e-08	27.7
WP_077325510.1\|511587_511827_-	hypothetical protein	NA	NA	NA	NA
WP_147525504.1\|511930_512128_-	hypothetical protein	NA	NA	NA	NA
WP_077325514.1\|512695_513112_-	SPFH domain-containing protein	A3F634	Streptococcus_phage	5.3e-22	38.2
WP_145983788.1\|513472_513790_-	hypothetical protein	NA	NA	NA	NA
WP_158520176.1\|513907_514078_-	hypothetical protein	NA	NA	NA	NA
WP_145983789.1\|514392_514602_+	hypothetical protein	NA	NA	NA	NA
WP_172622373.1\|514588_514816_-	hypothetical protein	NA	NA	NA	NA
WP_077325520.1\|515123_515324_+	hypothetical protein	NA	NA	NA	NA
WP_077325522.1\|515362_515566_-	hypothetical protein	NA	NA	NA	NA
WP_077325524.1\|515672_516467_+	hypothetical protein	NA	NA	NA	NA
WP_077325526.1\|516450_516687_-	hypothetical protein	NA	NA	NA	NA
WP_077325528.1\|516761_516962_+	hypothetical protein	NA	NA	NA	NA
WP_077325530.1\|516979_517198_-	hypothetical protein	NA	NA	NA	NA
WP_055160725.1\|517304_517538_+	hypothetical protein	NA	NA	NA	NA
WP_155512797.1\|517518_517683_-	hypothetical protein	NA	NA	NA	NA
WP_055160722.1\|517706_517940_-	DUF739 family protein	A0A2K9V3Z0	Faecalibacterium_phage	9.2e-08	46.4
WP_055160851.1\|518102_518549_+	helix-turn-helix transcriptional regulator	D2XR39	Bacillus_phage	2.2e-21	43.9
WP_070097644.1\|518569_518986_+	ImmA/IrrE family metallo-endopeptidase	Q0H245	Geobacillus_phage	1.3e-28	48.1
WP_077325532.1\|519158_520238_+	Abi family protein	X2L062	Streptococcus_phage	4.4e-20	29.7
WP_158520177.1\|520493_521684_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_009203066.1\|521919_522504_-	cytidylate kinase-like family protein	NA	NA	NA	NA
521700:521715	attR	NA	NA	NA	NA
WP_009203067.1\|522521_523214_-	LrgB family protein	NA	NA	NA	NA
WP_077325536.1\|523206_523566_-	CidA/LrgA family protein	NA	NA	NA	NA
WP_077327701.1\|529940_531191_-	hypothetical protein	NA	NA	NA	NA
WP_009204155.1\|531458_532061_-	sigma-70 family RNA polymerase sigma factor	A0A1I9S6C0	Bacillus_phage	2.7e-06	32.0
WP_008391852.1\|532064_532805_-	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_008391851.1\|532794_533250_-	ribonuclease III	NA	NA	NA	NA
WP_077325538.1\|533234_534638_-\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	2.8e-46	32.3

DBSCAN-SWA_4

1880127 : 1901980

Streptococcus_phage(94.12%)

integrase,transposase

attL 1876159:1876174|attR 1894448:1894463

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1876159:1876174	attL	NA	NA	NA	NA
WP_009271880.1\|1880127_1881318_-\|integrase	site-specific integrase	A0A1S5SEW7	Streptococcus_phage	3.1e-155	67.3
WP_004613735.1\|1881395_1881599_-	excisionase	A0A1S5SF07	Streptococcus_phage	2.5e-25	82.1
WP_025487352.1\|1881973_1882213_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_008787630.1\|1882205_1882634_-	hypothetical protein	A0A1S5SEW0	Streptococcus_phage	3.2e-22	43.1
WP_008787629.1\|1882913_1883138_-	hypothetical protein	NA	NA	NA	NA
WP_008787628.1\|1883169_1883595_-	hypothetical protein	NA	NA	NA	NA
WP_008787627.1\|1883569_1883854_+	topoisomerase DNA-binding C4 zinc finger domain-containing protein	A0A1X9I6W8	Streptococcus_phage	4.9e-35	100.0
WP_077325578.1\|1884028_1885651_-\|transposase	IS1182 family transposase	Q9MBP7	Staphylococcus_prophage	5.6e-51	28.9
WP_023948524.1\|1886133_1886217_+	23S rRNA methyltransferase attenuation leader peptide	NA	NA	NA	NA
WP_002292226.1\|1886341_1887079_+	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	1.4e-134	99.6
WP_008787625.1\|1887644_1888061_-	hypothetical protein	NA	NA	NA	NA
WP_008787624.1\|1888057_1888261_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_008787623.1\|1888361_1889273_-	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	2.2e-84	53.6
WP_008787622.1\|1889290_1890298_-	lysozyme family protein	A0A1S5SEZ8	Streptococcus_phage	6.4e-130	67.6
WP_008787621.1\|1890294_1892499_-	MFS transporter	A0A1S5SF30	Streptococcus_phage	1.6e-181	51.1
WP_008787620.1\|1892498_1894949_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	76.4
1894448:1894463	attR	NA	NA	NA	NA
WP_009243016.1\|1894926_1895325_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	4.1e-48	73.0
WP_002323345.1\|1895441_1895945_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	7.5e-55	60.8
WP_008787619.1\|1895962_1896466_-	antirestriction protein ArdA	NA	NA	NA	NA
WP_008787618.1\|1896384_1896681_-	hypothetical protein	NA	NA	NA	NA
WP_008787617.1\|1896790_1897411_-	hypothetical protein	NA	NA	NA	NA
WP_002323342.1\|1897500_1897722_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	9.0e-29	87.7
WP_017143882.1\|1897722_1897857_-	DUF3789 domain-containing protein	NA	NA	NA	NA
WP_008787615.1\|1897869_1899066_-	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	4.7e-148	62.3
WP_077326645.1\|1899249_1900644_-	ATP-binding protein	A0A1S5SFB5	Streptococcus_phage	8.7e-178	65.9
WP_021738773.1\|1900740_1901154_-	DUF3795 domain-containing protein	NA	NA	NA	NA
WP_077326647.1\|1901254_1901638_-	YdcP family protein	A0A1S5SF96	Streptococcus_phage	4.0e-32	55.1
WP_002323337.1\|1901653_1901980_-	YdcP family protein	A0A1S5SF38	Streptococcus_phage	2.4e-25	52.4

DBSCAN-SWA_5

1960168 : 2058915

111

Clostridium_phage(20.0%)

holin,tRNA,transposase,tail,portal,terminase,head,protease,integrase,capsid,plate

attL 1981902:1981932|attR 2027438:2027468

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_077326702.1\|1960168_1961344_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_077326704.1\|1961653_1963723_+	MMPL family transporter	NA	NA	NA	NA
WP_077326706.1\|1963736_1965707_+	hypothetical protein	NA	NA	NA	NA
WP_077326708.1\|1965877_1966879_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_015530752.1\|1966968_1967385_+	hypothetical protein	NA	NA	NA	NA
WP_077326710.1\|1968162_1969620_+	anthranilate synthase component I	NA	NA	NA	NA
WP_077326712.1\|1969616_1971260_+	bifunctional anthranilate synthase component II/anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	7.1e-70	43.7
WP_008390653.1\|1971260_1972052_+	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	1.5e-46	43.7
WP_077326714.1\|1972048_1972708_+	phosphoribosylanthranilate isomerase	NA	NA	NA	NA
WP_077326716.1\|1972700_1973891_+	tryptophan synthase subunit beta	NA	NA	NA	NA
WP_009265333.1\|1973880_1974669_+	tryptophan synthase subunit alpha	NA	NA	NA	NA
WP_009265332.1\|1974782_1975973_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_077326718.1\|1975999_1977055_+	histidinol-phosphate transaminase	NA	NA	NA	NA
WP_008390647.1\|1977158_1978103_+	hypothetical protein	NA	NA	NA	NA
WP_044922292.1\|1978192_1979338_+	AI-2E family transporter	NA	NA	NA	NA
WP_008390644.1\|1979334_1980183_+	thymidylate synthase	A0A0H3V0R8	Geobacillus_virus	2.2e-62	45.0
WP_008390643.1\|1980198_1980684_+	dihydrofolate reductase	A0A076GDN3	Bacillus_phage	3.4e-28	43.8
WP_077326720.1\|1980975_1981680_+	M15 family metallopeptidase	NA	NA	NA	NA
1981902:1981932	attL	NA	NA	NA	NA
WP_077326722.1\|1982150_1983809_+	AAA family ATPase	NA	NA	NA	NA
WP_077326724.1\|1983860_1984154_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_162494565.1\|1984405_1984849_+	hypothetical protein	V9QKZ6	Oenococcus_phage	6.5e-18	50.5
WP_077326728.1\|1984872_1985742_+	YARHG domain-containing protein	NA	NA	NA	NA
WP_077326730.1\|1985827_1986184_+	hypothetical protein	NA	NA	NA	NA
WP_077326732.1\|1986273_1987731_+	bacterial Ig-like domain-containing protein	NA	NA	NA	NA
WP_077326733.1\|1988026_1988413_-	peptidoglycan-binding protein	NA	NA	NA	NA
WP_009204015.1\|1988824_1990288_-	recombinase family protein	A0A0S2SXR4	Bacillus_phage	2.9e-30	29.1
WP_009204016.1\|1990547_1990760_+	helix-turn-helix transcriptional regulator	I3VYZ1	Thermoanaerobacterium_phage	2.4e-07	46.7
WP_009204018.1\|1990985_1992044_-	3'-5' exoribonuclease	X2KQX9	Campylobacter_phage	1.4e-58	41.4
WP_009204019.1\|1992071_1992461_-	helix-turn-helix transcriptional regulator	A0A2K9V305	Faecalibacterium_phage	2.3e-19	63.8
WP_009204020.1\|1992659_1992824_+	hypothetical protein	NA	NA	NA	NA
WP_009204021.1\|1992804_1993038_-	hypothetical protein	NA	NA	NA	NA
WP_077326735.1\|1993148_1993370_+	hypothetical protein	NA	NA	NA	NA
WP_077326737.1\|1993902_1994556_+	hypothetical protein	NA	NA	NA	NA
WP_055232120.1\|1994560_1994860_-	hypothetical protein	NA	NA	NA	NA
WP_167543158.1\|1995175_1995325_+	hypothetical protein	NA	NA	NA	NA
WP_154663015.1\|1995596_1995758_+	hypothetical protein	NA	NA	NA	NA
WP_055232118.1\|1995851_1996316_+	hypothetical protein	NA	NA	NA	NA
WP_015530765.1\|1996308_1996758_+	hypothetical protein	NA	NA	NA	NA
WP_015530766.1\|1996768_1996945_+	hypothetical protein	NA	NA	NA	NA
WP_055232116.1\|1997122_1997668_+	hypothetical protein	NA	NA	NA	NA
WP_009204034.1\|1997699_1997885_+	hypothetical protein	NA	NA	NA	NA
WP_055232113.1\|1997887_1998319_+	VRR-NUC domain-containing protein	A0A2D1GNH3	Pseudomonas_phage	6.1e-13	41.4
WP_055232111.1\|1998330_1998543_+	hypothetical protein	NA	NA	NA	NA
WP_099046225.1\|1998720_1998987_+	single-stranded DNA-binding protein	A0A2H4J8K2	uncultured_Caudovirales_phage	4.6e-11	60.0
WP_077326741.1\|1998983_1999412_+	hypothetical protein	NA	NA	NA	NA
WP_055232100.1\|1999807_2000218_+\|transposase	transposase	NA	NA	NA	NA
WP_055232098.1\|2000227_2000581_+	hypothetical protein	A0A2I7R1U5	Vibrio_phage	1.7e-05	28.0
WP_055232096.1\|2000567_2000783_+	hypothetical protein	NA	NA	NA	NA
WP_077327827.1\|2001097_2001403_+	hypothetical protein	NA	NA	NA	NA
WP_172622391.1\|2002059_2002281_+	hypothetical protein	NA	NA	NA	NA
WP_077326743.1\|2002306_2002720_+	hypothetical protein	NA	NA	NA	NA
WP_158520187.1\|2002734_2002896_+	hypothetical protein	NA	NA	NA	NA
WP_077326745.1\|2003126_2003594_+	hypothetical protein	NA	NA	NA	NA
WP_009204053.1\|2003675_2004164_+\|terminase	phage terminase small subunit P27 family	NA	NA	NA	NA
WP_040344398.1\|2005901_2007149_+\|portal	phage portal protein	A6M949	Geobacillus_virus	1.1e-115	50.7
WP_077327830.1\|2007205_2007991_+\|protease	Clp protease ClpP	A0A0A7RTN2	Clostridium_phage	4.3e-57	54.2
WP_009204057.1\|2007965_2009285_+\|capsid	phage major capsid protein	H7BVF4	unidentified_phage	1.2e-80	40.4
WP_077326747.1\|2009288_2009588_+\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_145983801.1\|2009580_2009940_+\|head	phage head closure protein	NA	NA	NA	NA
WP_040344399.1\|2009899_2010085_+	hypothetical protein	NA	NA	NA	NA
WP_009204061.1\|2010074_2010545_+	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_077326749.1\|2010541_2011000_+	hypothetical protein	NA	NA	NA	NA
WP_009204063.1\|2010980_2012039_+\|tail	phage tail sheath subtilisin-like domain-containing protein	A0A090D804	Clostridium_phage	1.4e-63	41.0
WP_009204064.1\|2012048_2012483_+\|tail	phage tail tube protein	A0A0A7RVT1	Clostridium_phage	2.1e-29	47.5
WP_009204065.1\|2012496_2012901_+	phage XkdN-like protein	NA	NA	NA	NA
WP_009204066.1\|2012927_2013071_+	hypothetical protein	NA	NA	NA	NA
WP_077326751.1\|2013060_2015256_+\|tail	phage tail tape measure protein	A0A0A7RUN0	Clostridium_phage	2.2e-90	45.5
WP_009204068.1\|2015266_2015950_+	LysM peptidoglycan-binding domain-containing protein	A0A0K2SUI2	Clostridium_phage	3.4e-26	44.6
WP_077326753.1\|2015946_2017665_+	C40 family peptidase	A0A0K2SUC1	Clostridium_phage	2.7e-88	39.0
WP_009204070.1\|2017664_2017901_+	hypothetical protein	NA	NA	NA	NA
WP_009204071.1\|2017900_2018308_+	DUF2634 domain-containing protein	A0A1V0DZX2	Clostridioides_phage	3.9e-09	31.2
WP_077326757.1\|2018300_2019359_+\|plate	baseplate J/gp47 family protein	H7BWD5	unidentified_phage	1.9e-60	38.0
WP_009204073.1\|2019349_2019886_+	DUF2313 domain-containing protein	NA	NA	NA	NA
WP_077326759.1\|2019888_2020269_+	hypothetical protein	NA	NA	NA	NA
WP_055160824.1\|2020621_2021617_+\|integrase	tyrosine-type recombinase/integrase	A0A2H4JAA2	uncultured_Caudovirales_phage	7.4e-38	30.0
WP_008393607.1\|2022093_2022336_-	hypothetical protein	NA	NA	NA	NA
WP_077326761.1\|2022431_2023343_+	hypothetical protein	H7BV37	unidentified_phage	6.9e-83	58.4
WP_077326763.1\|2023352_2023646_+	Ig-like domain-containing protein	NA	NA	NA	NA
WP_015530789.1\|2023642_2023927_+	hypothetical protein	NA	NA	NA	NA
WP_009204619.1\|2023926_2024094_+	hypothetical protein	NA	NA	NA	NA
WP_009204620.1\|2024173_2024656_+\|holin	phage holin family protein	NA	NA	NA	NA
WP_077326765.1\|2024656_2025355_+	CHAP domain-containing protein	NA	NA	NA	NA
WP_009204623.1\|2025814_2026009_+	hypothetical protein	NA	NA	NA	NA
WP_015530792.1\|2026055_2026943_-	stage II sporulation protein	NA	NA	NA	NA
WP_008390638.1\|2026978_2027434_+	hypothetical protein	NA	NA	NA	NA
WP_008390637.1\|2027500_2027983_+\|tRNA	Cys-tRNA(Pro) deacylase	NA	NA	NA	NA
2027438:2027468	attR	NA	NA	NA	NA
WP_008390636.1\|2027995_2028541_+	carbonic anhydrase	NA	NA	NA	NA
WP_077326767.1\|2028560_2029430_+	N-acetylmuramoyl-L-alanine amidase	NA	NA	NA	NA
WP_039862599.1\|2029472_2029832_+	MptD family putative ECF transporter S component	NA	NA	NA	NA
WP_009265326.1\|2030545_2031709_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	Q331V1	Clostridium_botulinum_C_phage	1.6e-116	57.8
WP_008390627.1\|2031900_2032074_+	DUF4250 domain-containing protein	NA	NA	NA	NA
WP_040344614.1\|2032131_2032833_+	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	2.3e-17	29.3
WP_009265322.1\|2036069_2037386_+	cyclomaltodextrinase	NA	NA	NA	NA
WP_008390622.1\|2037455_2039003_+	ribonuclease Y	NA	NA	NA	NA
WP_008390621.1\|2039081_2039612_+	NUDIX hydrolase	NA	NA	NA	NA
WP_008390620.1\|2039680_2040244_+	hypothetical protein	NA	NA	NA	NA
WP_008390619.1\|2040267_2041296_-	3-deoxy-7-phosphoheptulonate synthase	S4W5F1	Pandoravirus	5.9e-46	32.2
WP_009204631.1\|2041784_2042402_+	ECF transporter S component	NA	NA	NA	NA
WP_077326769.1\|2042465_2042858_-	thioesterase family protein	NA	NA	NA	NA
WP_022091036.1\|2043024_2043645_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_022091037.1\|2043648_2044107_+	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_055072676.1\|2044129_2045266_+	amidohydrolase	NA	NA	NA	NA
WP_008390612.1\|2045366_2046857_+	threonine synthase	NA	NA	NA	NA
WP_077326771.1\|2047352_2051063_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_009203573.1\|2051138_2051456_+	hypothetical protein	NA	NA	NA	NA
WP_008390608.1\|2051537_2052299_+	serine/threonine-protein phosphatase	NA	NA	NA	NA
WP_077326773.1\|2052220_2053804_+	serine/threonine protein kinase	G9BWE0	Planktothrix_phage	4.4e-08	30.6
WP_077326776.1\|2053800_2055906_+	hypothetical protein	NA	NA	NA	NA
WP_077326778.1\|2055964_2056672_+	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_009265489.1\|2056684_2057785_+	chorismate synthase	A0A291AU41	Pandoravirus	3.8e-75	43.6
WP_008390603.1\|2057787_2058915_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	4.3e-90	45.1

DBSCAN-SWA_6

3000582 : 3020628

Streptococcus_phage(94.74%)

integrase

attL 2991502:2991517|attR 3024911:3024926

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2991502:2991517	attL	NA	NA	NA	NA
WP_001291561.1\|3000582_3001800_-\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
WP_000814511.1\|3001881_3002085_-	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
WP_000857133.1\|3002545_3002776_-	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_000804885.1\|3002772_3003195_-	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_001227347.1\|3003699_3004053_+	helix-turn-helix domain-containing protein	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
WP_000336323.1\|3004112_3004280_-	cysteine-rich KTR domain-containing protein	D0R0F6	Streptococcus_phage	1.6e-14	68.0
WP_077327446.1\|3004398_3006318_-	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	99.2
WP_001791010.1\|3006333_3006450_-	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_001224320.1\|3006694_3007630_-	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	7.7e-170	99.0
WP_000769868.1\|3007626_3008628_-	lysozyme family protein	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_000804748.1\|3008624_3010802_-	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
WP_000331160.1\|3010804_3013252_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
WP_000506270.1\|3013235_3013742_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000342539.1\|3013716_3014214_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
WP_001009056.1\|3014330_3014552_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000398284.1\|3014594_3015800_-	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
WP_000879507.1\|3015822_3015975_-	hypothetical protein	NA	NA	NA	NA
WP_000813488.1\|3015977_3017363_-	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000985015.1\|3017391_3017778_-	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000420682.1\|3017793_3018108_-	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
WP_077327449.1\|3018675_3019740_+	WD40 repeat domain-containing protein	NA	NA	NA	NA
WP_055159336.1\|3019755_3020628_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.2e-33	39.5
3024911:3024926	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LR699012

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection