CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LR738723	Streptococcus suis isolate GD-0088 chromosome 1	3 crisprs	PrimPol,RT,DinG,csa3,cas3,DEDDh	0	1	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LR738723_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LR738723_1

394818-395031

Orphan

Consensus_repeat	Method
TAAAAGGTTGGAGATTGGAA	PILER-CR

3 spacers

The CRISPR arrays of NZ_LR738723_1

>merge|NZ_LR738723|1|394818-395031|PILER-CR
TAAAAGGTTGGAGATTGGAATCGTCGGTAGACGATTCTCATTGTACGTGGGACGTCCTAGAAGGTTGGAGATTGGAACTGCCGTGCCGGCAGGCAGTTTTCTTTATACTCAAAAGTCCGGGGGACAGTCATTTTTATTAAAAGGTTGGAGATTGGAATCGTCGGTAGACGATTCTCATTGTACGTGGGATGTCCTAGAAGGTTGGAGATTGGAA

>NZ_LR738723|1|1|394818-395031|PILER-CR
TAAAAGGTTGGAGATTGGAA	TCGTCGGTAGACGATTCTCATTGTACGTGGGACGTCC
TAGAAGGTTGGAGATTGGAA	CTGCCGTGCCGGCAGGCAGTTTTCTTTATACTCAAAAGTCCGGGGGACAGTCATTTTTAT
TAAAAGGTTGGAGATTGGAA	TCGTCGGTAGACGATTCTCATTGTACGTGGGATGTCC
TAGAAGGTTGGAGATTGGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LR738723.1\|WP_170240223.1\|399175_399493_+\|lactoylglutathione-lyase	unknown	unknown	gnl\|CDD\|226134
NZ_LR738723.1\|WP_004194195.1\|394066_394783_+\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|237084
NZ_LR738723.1\|WP_024394801.1\|381682_382093_+\|peptide-deformylase	unknown	unknown	gnl\|CDD\|181704
NZ_LR738723.1\|WP_024403007.1\|396152_396698_+\|ECF-type-riboflavin-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|184218
NZ_LR738723.1\|WP_011922661.1\|384994_386503_+\|4-alpha-glucanotransferase	unknown	unknown	gnl\|CDD\|237738
NZ_LR738723.1\|WP_024381722.1\|401274_402108_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NZ_LR738723.1\|WP_009909407.1\|397936_398920_+\|rhodanese-related-sulfurtransferase	unknown	unknown	gnl\|CDD\|234663
NZ_LR738723.1\|WP_024406016.1\|399604_401278_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213192
NZ_LR738723.1\|WP_074389309.1\|382713_384813_+\|ATP-dependent-Clp-protease-ATP-binding-subunit	unknown	unknown	gnl\|CDD\|223616
NZ_LR738723.1\|WP_004194192.1\|395283_396132_+\|S-adenosyl-l-methionine-hydroxide-adenosyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224824
NZ_LR738723.1\|WP_024403006.1\|396805_397726_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LR738723.1\|WP_004194205.1\|388987_389695_-\|UTRA-domain-containing-protein	unknown	unknown	gnl\|CDD\|274116
NZ_LR738723.1\|WP_011921981.1\|403275_405462_-\|PBP1A-family-penicillin-binding-protein	unknown	unknown	gnl\|CDD\|273955
NZ_LR738723.1\|WP_004194196.1\|393594_393906_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|163261
NZ_LR738723.1\|WP_074389311.1\|390718_392887_+\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|131058
NZ_LR738723.1\|WP_011922666.1\|392957_393584_-\|DUF2812-domain-containing-protein	unknown	unknown	gnl\|CDD\|378589
NZ_LR738723.1\|WP_024406014.1\|389893_390685_+\|endonuclease/exonuclease/phosphatase-family-protein	unknown	unknown	gnl\|CDD\|197313
NZ_LR738723.1\|WP_004195223.1\|402267_402471_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NZ_LR738723.1\|WP_074411823.1\|402512_403217_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	unknown	unknown	gnl\|CDD\|234637
NZ_LR738723.1\|WP_074389310.1\|386495_388760_+\|glycogen/starch/alpha-glucan-family-phosphorylase	unknown	unknown	gnl\|CDD\|340853

Protein	Function_ID	Function_description	E-value
NZ_LR738723.1\|WP_170240223.1\|399175_399493_+\|lactoylglutathione-lyase	gnl\|CDD\|226134	COG3607, COG3607, Predicted lactoylglutathione lyase [General function prediction only].	1.17228e-15
NZ_LR738723.1\|WP_004194195.1\|394066_394783_+\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|237084	PRK12378, PRK12378, YebC/PmpR family DNA-binding transcriptional regulator.	7.09301e-135
NZ_LR738723.1\|WP_024394801.1\|381682_382093_+\|peptide-deformylase	gnl\|CDD\|181704	PRK09218, PRK09218, peptide deformylase; Validated.	3.43387e-86
NZ_LR738723.1\|WP_024403007.1\|396152_396698_+\|ECF-type-riboflavin-transporter-substrate-binding-protein	gnl\|CDD\|184218	PRK13661, PRK13661, ECF-type riboflavin transporter substrate-binding protein.	8.67718e-92
NZ_LR738723.1\|WP_011922661.1\|384994_386503_+\|4-alpha-glucanotransferase	gnl\|CDD\|237738	PRK14508, PRK14508, 4-alpha-glucanotransferase; Provisional.	0
NZ_LR738723.1\|WP_024381722.1\|401274_402108_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	3.10551e-38
NZ_LR738723.1\|WP_009909407.1\|397936_398920_+\|rhodanese-related-sulfurtransferase	gnl\|CDD\|234663	PRK00142, PRK00142, rhodanese-related sulfurtransferase.	0
NZ_LR738723.1\|WP_024406016.1\|399604_401278_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	5.38673e-92
NZ_LR738723.1\|WP_074389309.1\|382713_384813_+\|ATP-dependent-Clp-protease-ATP-binding-subunit	gnl\|CDD\|223616	COG0542, clpA, ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones].	0
NZ_LR738723.1\|WP_004194192.1\|395283_396132_+\|S-adenosyl-l-methionine-hydroxide-adenosyltransferase-family-protein	gnl\|CDD\|224824	COG1912, COG1912, Uncharacterized conserved protein [Function unknown].	2.06971e-121
NZ_LR738723.1\|WP_004194205.1\|388987_389695_-\|UTRA-domain-containing-protein	gnl\|CDD\|274116	TIGR02404, Trehalose_operon_transcriptional_repressor, trehalose operon repressor, B. subtilis-type. This family consists of repressors of the GntR family typically associated with trehalose utilization operons. Trehalose is imported as trehalose-6-phosphate and then hydrolyzed by alpha,alpha-phosphotrehalase to glucose and glucose-6-P. This family includes repressors mostly from Gram-positive lineages and does not include the TreR from E. coli. [Regulatory functions, DNA interactions].	3.21951e-64
NZ_LR738723.1\|WP_011921981.1\|403275_405462_-\|PBP1A-family-penicillin-binding-protein	gnl\|CDD\|273955	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NZ_LR738723.1\|WP_004194196.1\|393594_393906_-\|transcriptional-regulator	gnl\|CDD\|163261	TIGR03433, padR_acidobact, transcriptional regulator, Acidobacterial, PadR-family. Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions].	2.51666e-11
NZ_LR738723.1\|WP_074389311.1\|390718_392887_+\|PTS-transporter-subunit-EIIC	gnl\|CDD\|131058	TIGR02003, PTS_system_glucose-specific_IIBC_component, PTS system, IIBC component. This model represents a family of fused B and C components of PTS enzyme II. This clade is a member of a larger family which contains enzyme II's specific for a variety of sugars including glucose (TIGR02002) and N-acetylglucosamine (TIGR01998). None of the members of this clade have been experimentally characterized. This clade includes sequences from Streptococcus and Enterococcus which also include a C-terminal A domain as well as Bacillus and Clostridium which do not. In nearly all cases, these species also contain an authentic glucose-specific PTS transporter. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
NZ_LR738723.1\|WP_011922666.1\|392957_393584_-\|DUF2812-domain-containing-protein	gnl\|CDD\|378589	pfam11193, DUF2812, Protein of unknown function (DUF2812). This is a bacterial family of uncharacterized proteins, however some members of this family are annotated as membrane proteins.	6.08987e-21
NZ_LR738723.1\|WP_024406014.1\|389893_390685_+\|endonuclease/exonuclease/phosphatase-family-protein	gnl\|CDD\|197313	cd09079, RgfB-like, Streptococcus agalactiae RgfB, part of a putative two component signal transduction system, and related proteins. This family includes Streptococcus agalactiae RgfB (for regulator of fibrinogen binding) and related proteins. The function of RgfB is unknown. It is part of a putative two component signal transduction system designated rgfBDAC (the rgf locus was identified in a screen for mutants of Streptococcus agalactiae with altered binding to fibrinogen). RgfA,-C,and -D do not belong to this superfamily: rgfA encodes a putative response regulator, and rgfC, a putative histidine kinase. All four genes are co-transcribed, and may be involved in regulating expression of bacterial cell surface components. This family belongs to the large EEP (exonuclease/endonuclease/phosphatase) superfamily that contains functionally diverse enzymes that share a common catalytic mechanism of cleaving phosphodiester bonds.	8.98806e-126
NZ_LR738723.1\|WP_004195223.1\|402267_402471_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	5.32735e-32
NZ_LR738723.1\|WP_074411823.1\|402512_403217_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	gnl\|CDD\|234637	PRK00107, gidB, 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG.	3.12413e-81
NZ_LR738723.1\|WP_074389310.1\|386495_388760_+\|glycogen/starch/alpha-glucan-family-phosphorylase	gnl\|CDD\|340853	cd04300, GT35_Glycogen_Phosphorylase, glycogen phosphorylase and similar proteins. This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	0

>NZ_LR738723.1|WP_004194195.1|394066_394783_+|YebC/PmpR-family-DNA-binding-transcriptional-regulator
MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPETNSALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSNVNRTAANVRSAFGKNGGNMGASGSVSFMFDKKGVVVFAGDDADAIFELLLEADVEVDDVEAEDGTITVYTAPTDLHKAIVALKESGIQEFNVTELEMIPQSEVSLEGDDLATFEKLYDALEDDEDVQKIYTNVDGF
>NZ_LR738723.1|WP_004194196.1|393594_393906_-|transcriptional-regulator
MKRNKHLPLTETTYYILLALLEPAHGYHIMQKVEDMSDGDVKIAAGTMYGAIENLLKLKWICSVPSSDKRRKVYQVTATGQEIIKLETQRIQKLHHIAKELGF
>NZ_LR738723.1|WP_011922666.1|392957_393584_-|DUF2812-domain-containing-protein
MIRHKLFTSLQEEEHWINSIQSEGYQLVKVTPWTATYHFEKCSRTPHPVRLDFHEHIAKGEYSNYLSLFEDCGWQPIQGSRRCGIHYFQQTIETSSTEIFSDTESKKAFYSRYQNYAYSYFGLFLTLFFIHYQVGLQNGYTLWNPKSWYLTPGLWERTGTSFWFGFLFETPFALFRSGIIPLFFLAWSIYFLHIAEKGKKEAKKLEKY
>NZ_LR738723.1|WP_074389311.1|390718_392887_+|PTS-transporter-subunit-EIIC
MKKFLSFEFWQKFGKCLMVVIAVMPAAGLMVSIGNSIPLISPESELLIRIGNIIAQIGWGIIGNLHLLFALAIGGSWAKEKAGGAFSAGLAFILINLITGHFFGVTTDMLADAAATVTTVFGTEIPVSGYFVNILGQPALNMGVFVGIIAGFVGATTYNKYYNYRKLPDVLTFFNGKRFVPFVVIYRSVLVALGLAIFWPVVQTEINSFGKWIASSQDTAPILAPFVYGTLERLLLPFGLHHMLTIPMNYTSLGGTYDILTGAQAGTQVFGQDPLWLAWITDLINLKDAGDMAQYNDLLANITPARFKVGQMIGSSGILMGLTYAMYRNVDEDKKHKYKGMFISSALAVFLTGVTEPIEFMFMFAAMPLYVVYAFVQGAAFAMADIVNLRMHSFGNIEFLTRTPMAIKAGIGMDVINFIWVTALFAVGMYFIANFMIKKFNLATAGRNGNYDTETTDVVSNSNVDTADANSQVVQIINLLGGRDNIADVDACMTRLRVSVKDVAQVGDENAWKQAGAMGLIIKDSGVQAVYGPKADVLKSDIQDLLESGVAIPRTEIVATEEVAPETQFKGVTETVYSVAEGQAIAITEVKDPVFSQKMMGDGYAVEPSSGNVYAPVSGIVTSVFPTKHAVGILSDKGVEVLVHVGLDTVALNGAPFSTKVTDGQRVEAGDLLLVADLEAIRSAGRETTIVVAFTNTAEIKSVSLENLGQVSQDSQVATVEL
>NZ_LR738723.1|WP_024406014.1|389893_390685_+|endonuclease/exonuclease/phosphatase-family-protein
MKLLTINVHAWLEERQDEKLDVLAQTIAEKAYDVIALQEVNQLITADLVTKDLKADNYGLILLEKLRALGQFDYSYYWSNSHIGYDKYEEGIAFLTKLPVYEVDPFYCSQNKSVDSILSRKIMGLTVFYQDQLIDLYSCHINLPGSEEENQLDNIRTIVERTGNRRFKILMGDFNTDAFSDREAYEAITELGLYDSYNLAMEKDQGITVEKAIDGWAGHSQEKRLDYIFLNQKKEVLSSLVIFNGENRPIISDHFGVEVEINV
>NZ_LR738723.1|WP_004194205.1|388987_389695_-|UTRA-domain-containing-protein
MSKYKKVYQDIKKKIEEQVWSTGQALPTENELMEVYSYSKDTIRKALSLLEMDGYIQKKQGKSSIVIEHGLMKDQYLSEIKTAGELNKRSQHQIQTQLTSLYIIQGQEDLMSTFEVDDKVDFYRVSRVRTIDGERLEYDISYFDRRVVPYLSKEIAESSIYRYLEEELHLTISHSRREISFRFANEEEKQLMDLGDYDMVVVVTSITYLSNGQAFQYGTISYRPDKVSFVSMAKR
>NZ_LR738723.1|WP_074389310.1|386495_388760_+|glycogen/starch/alpha-glucan-family-phosphorylase
MTKFTTFAETNTSKKLADLTNEEIYLQLLNYVKDAAASKPKNTGKRKVYYISAEFLIGKLLSNNLINLGVYKDVQAELAAAGKSLAQVEDVEPEPSLGNGGLGRLASCFVDSMSTLAINGEGVGLNYHCGLFRQVFKKNEQEAEPNFWIENDSWLIPTTISYDVPFKNFTLKSKLDRLDILGYKKETKNYLNLFDIESVNYDLITDGISFDKTDIKENLTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLLIDEAIERGSNLHDLVDYAYVQINDTHPSMVIPELIRLLTEKHGIEFAEAVAIVKNMTGYTNHTILAEALEKWPLEFLEEVVPHLVDIIKELDALIRAEIKDPAVQIIDESGRVHMAHMDIHFSNSVNGVAALHTEILKNSELKAFYELYPEKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLLAFADDKEVHAKLAEIKFNNKLALKRYLKDNKGIELDENSIIDTQIKRFHEYKRQQMNALYVIHKYLEIKNGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVNKYLNVHLVENYNVTVAEKLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAELAGMDNIYTFGKDSDTIIDLYDKAGYISADYYNGDANIKRAVDFIVSDEVKALGNEERLGRLHHELISKDWFMTLIDLAEYIEVKEQVFADYEDQDSWNKKVVHNIAKAGFFSSDRTIEQYNEDIWHSN
>NZ_LR738723.1|WP_011922661.1|384994_386503_+|4-alpha-glucanotransferase
MTNRTSGILMHITSLPGKFGIGTFGQSAYDFVDFLVETKQTYWQILPLTTTSYGDSPYQSFSAIAGNTHLIDFDLLVEDGLLATEDFQDVNFGDNPEKVDYALIYQVRRPILEKAVQAFLQDDKKKAAFLEFEKANSSWLTDYAEFMAIKEYFGNKALQEWEDKKVVARNEEALDKYRLELANQIDYYKVTQYFFFSQWKQLKEYANKHHIKIIGDMPIYVSADSVEVWTKPQLFKLDSERKPLYVAGVPADNFSADGQLWGNPIYDWPEHEKTGYNWWIYRIHESFKLYDVLRIDHFKGFSDFWQVDGKAEVAKVGTWEPGPGYNLFKAVKETLGDLPIIAEDLGNIDAKARKLLADCGYPGMKILEFGFFDVTGKSIDAPHRCIPNSVAYTGTHDNEVVNGWYNNLDPEQQEYVDAYSNRKPIEKVSQAMLRMLFATVSDTAIATMQDVLDLGEESRMNMPSTIGGNWEWRMKAEDLTQERKDFLTKMTLLYQRGNENHD
>NZ_LR738723.1|WP_074389309.1|382713_384813_+|ATP-dependent-Clp-protease-ATP-binding-subunit
MNNNFNNFNNMDDIFNQLMGNIGGYSTEGRRYSINGREVTPEEFAMYRQTGRLPQTEEVAQTQAKGQIKSDGILAKLGRNLTQDAREGKLDPVIGRNKEIQETSEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEAGTQYRGAFEENVQNLVDEVKKAGNIILFFDEIHQILGAGSTGGDTGSKGLADILKPALSRGELTVIGATTQDEYRNTIHKNAALARRFNEVKVNAPSAEDTYQILKGIKPLYEAHHNIELPDEVLRAAVDYSVQYIPQRSLPDKAIDLIDVTAAHLAAQHPVTDIQTLEAEMAEAKQLQLEAAEKEDYEKALNEKVRIDKLQKQIDNHTEQQKVVATVNDVAQAVERMTGIPVSQMGASDIERLKELKNRLAANVIGQDDAVEAVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGNKDAIIRLDMSEYSDRTAVSKLIGTTAGYIGYDDNSHTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGHLTDGQGNQVNFKNTIIIATSNAGFGYGMAEGEENQDIMDRIAPFFRPEFLNRFNAVIEFKHLDKDDLKAIVELLLAQVNNTLAKKGIQLTVTEAAKEFLMEEGYDKAMGARPLRRVIENQIRDKVTDYYLDHVDVKYLEADVVDGSIQIKEQSFA
>NZ_LR738723.1|WP_024394801.1|381682_382093_+|peptide-deformylase
MIQPIMKDIFFLQQKSEPATQLDVQVGQDLQDTLAANAHACVGMAANMIGVKKRIIIVNMGFTNLVMYNPVLISKAKPYQTEEGCLSLEGSRPTTRYQEIEVEFFDASWKKQSLKLTDFQAQIVQHELDHLEGIII
>NZ_LR738723.1|WP_004194192.1|395283_396132_+|S-adenosyl-l-methionine-hydroxide-adenosyltransferase-family-protein
MSNNLLVLQSDFGLVDGAVSAMIGVALQESRDLVVHHLTHDITPYNIFEGSYRLFQTVEYWPEGTTFVSVVDPGVGSKRKSVVALTEQNHYIVTPDNGTLSFIKKYVGIKAVREISEVANRRANTEHSYTFHGRDVYAYTGAKLASGHISFEEVGPELSVDKIVEIPTVPTEVGSDYVKGAIDILDVRFGSLWTSITREEFYTLQPQFEDRFEVTIYNNDMLVYQNQVTYGKSFADVRIGQPLIYINSLYRVGVAINQGSFAKAYNVGVGQNWHIEIKRISN
>NZ_LR738723.1|WP_024403007.1|396152_396698_+|ECF-type-riboflavin-transporter-substrate-binding-protein
MKNNSIKTVVATGIGAALFVVIGLLINIPTFVPNTSIQLQYAVQSLLAVVFGPVVGFLVGFIGHTLKDSLTYGPWWSWILASGVFGLVVGLTKKRLRIQEGIFEGKDILFFNLVQIAANVLAWGVIAPVLDILIYSEAANKVFAQGLVAGIANSITVAIAGTLLLAVYAKSQTKTGSLSKD
>NZ_LR738723.1|WP_024403006.1|396805_397726_+|hypothetical-protein
MVWTEEKLGPIIHSILNPDEEVLSLYQSKTTKSIYGCILWNNYYYKVFRVSNHPSQSTYKQPTFYDFHGEFYMKGAIRTYLYHTNSWYELSKQSYYLLLFFQKLWDEKQEVEASWQNGRIQIRLVVEEEGWQVHYRFPDNQAREVERLLASGMLVAIRSSRNFIKIRTSRFVAPYIALIKQRQLYRKKPSKAMLQWEKYQSQLIEIQRTYRLVEESAPQTFFGHWLNKVQLYLCSAIASYWEEVIKGVEWQDAREIKEQRKAEKPHNPIEDKWKENIARRHKRKVDQLIGHDTLEKLRQLKTELDD
>NZ_LR738723.1|WP_009909407.1|397936_398920_+|rhodanese-related-sulfurtransferase
MSKDIRVLLYYKYVPIENAKEYAAEHLAFCKSIGLKGRILIADEGINGTVSGDYETTQKYMDYVHANPLFSDLWFKIDEENEQAFKKMFVRYKKEIVHLGLEDNDFDNDIDPLVTTGAYLSPKEFKEALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKDPEVRGELWDGKMYVFDERIAVDVNHVNPVVVGKDWFDGTPCERYVNCGNPFCNRRILTSEENEHKYVRGCSAECRAHERNRYISENGLTRQEWAERLEAIGETLTPANA
>NZ_LR738723.1|WP_170240223.1|399175_399493_+|lactoylglutathione-lyase
MAGRFYEAIGFAVATFGDIKSATLPEGGNLILMQADSFAQRLPFQVVASGNEVLISLNVASREEVDRITERVEANSGQITGCLTDARGFYGASFTDLDGIILMRL
>NZ_LR738723.1|WP_024406016.1|399604_401278_+|ABC-transporter-ATP-binding-protein
MKKIIEFKDFTFKYQAQQEPTLKDIQLTIYQGEKVLIIGPSGSGKSTIGQCLNGIIPNIYKGEHNGSLLLDGQEAFNLSVYDKSLLVSTVLQDTDGQFIGLSVAEDLAFALENDMENQMVMKQKVGDWAERLSLTDLLAHRPQDLSGGQKQRVSLGGVLIDESPILLFDEPLANLDPKSGQDTIDLIDRLHKQEGTTTIIIEHRLEDVLYRQVDRVVLINDGRILFNGGPDDLLRTSLLQENGIREPLYLSTLRALGYPIAQAEHLSSVWEIDIEALNIASLPTLHFENGEKEALLEVKHLYFSYPNKQVLTDIQLTIHKGERLAIVGKNGAGKSTLAKVLCGFIQGEGEILWKGQSIKEDSVKERAERIGYVLQNPNQMISQTMIFDEVALGLRMRGVTEEEIEHRVHHILKVCGLYPFRNWPISALSYGQKKRVTIASILVLNPEIILLDEPTAGQDQRHYREMMEFLDQLNAQGHTIVMITHDMQLMLDYSDRAVVVVDGQIIEDASPAEILSDDMVIERANLKETSIFHLAERLGVNPLELTTFYMQEERRGR
>NZ_LR738723.1|WP_024381722.1|401274_402108_+|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MSQQKLIGYHPGTGFIHSLSAVSKLLFFLIVSILAMITYDTRLILFIAVFSLALFKMSGIRYKEISLVLILTIIFAAMNALMVHLFAPRYGVELYGADTPLLSGLGVYSLTSQQAFYLVNLLLKYFCTVPLAIIFLMTTHPSQFASSLNQIGVSYKVAYAVSLTMRYIPDIQEEFYTIRMSQEARGLELSRKGKLMDRIKGNLSLVIPLIFSSLERIDTISTAMELRRFGKNKKRTWYTQQPLQRIDYAVLLFILALVVVTIYLFFVNQGRFYNPWR
>NZ_LR738723.1|WP_004195223.1|402267_402471_+|cold-shock-protein
MVQGTVKWFNAEKGFGFIAQENGPDVFAHFSEIQSNGFKSLEDGQKVTFEVEQGQRGLQATNITKIG
>NZ_LR738723.1|WP_074411823.1|402512_403217_-|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG
MKPEVFYKTLADQGIQLTDQQKHQFHRYFQLLVEWNEKINLTAITEESEVYLKHLSLHSLQGHIQNEPLRLLDIGAGAGFPSLPMKIIFPQLDVTIIDSLNKRINFLHLLAEELELEGVHFYHGRAEDFAQDKNFRAQFDLVTARAVARMQILSELTIPYLKLHGKLIALKASSAEDELTQAKNALNLLFAKVIENHDYTLPNGDPRTLTIVEKKKETPNKFPRKAGMPNKRPL
>NZ_LR738723.1|WP_011921981.1|403275_405462_-|PBP1A-family-penicillin-binding-protein
MVNLLKTTTIKKALLITANILLAGAIIACLAGAALVVYYIQSAPELTEESLTATVSSKIYDKNGNLIADLGAEKRSSAKTEEIPTDLVNAIVAIEDQRFFNHRGVDVIRIAGSLINNLSGGRLQGGSTLDQQFIKLTYFSTSVEDQNLKRKIQEAWLATQLERRNTKQEILTYYINKVYMSNGNYGMKTAALAFYGKELKDLTLPQLALLAGMPQAPNQYDPYTNPEDAKARRDLVLAEMLEEKYIDNTQYEQAVLTPVTDGLQPLSNAAAYPAYMDNYLKQVVEEVEAKTGYNLLTTGMDVYTNVDPAAQQQLWNIYNTDMYVSYPDDLLQVASTVVDVSNGKVVAQLGGRKQETNVSFGTNQAVETNRDFGSTMKPITDYAPAFENGIYTSTADLILDGPYNYPGTPTPVNNWDKQYYGNISVKTAIQYSRNVTAVKALEATGLENALKFLNSVGINYPDIHYSNAISSNTSDTSSKYGASSEKMAAAYAAFANGGTYYAPQYVNKIVFSDGTVTEYAPKGTKVMSAETAYMMTDMMKAVMSYGYGLNASVSGVPMAGKTGTSNYTDSETDTILASIPEANYSYMVVPDENFVGYSSQYAMAVWTGYTNRMTPILDNSMRIATDVYHNMMLFMHSDYTATDWEMPSGLVRYGSNYYLRGSRSLSNAYNTYTSSSTSSSSSTETSETTEATTTSSETSSGTATETATSSTETATTGNNPATGQTDGQ

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Crispr_ID: NZ_LR738723_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LR738723_2

978718-978801

Orphan

Consensus_repeat	Method
AACTTCGTTCGCTCTATTTCCAACCTCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LR738723_2

>merge|NZ_LR738723|2|978718-978801|CRISPRCasFinder
AACTTCGTTCGCTCTATTTCCAACCTCCCAAGTTTCCCCAAACCTTTGTAGAAATGAACTTCGTTCGCTCAATTTCCAACCTCC

>NZ_LR738723|2|1|978718-978801|CRISPRCasFinder
AACTTCGTTCGCTCTATTTCCAACCTCC	CAAGTTTCCCCAAACCTTTGTAGAAATG
AACTTCGTTCGCTCAATTTCCAACCTCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LR738723.1\|WP_032500985.1\|972111_972939_+\|NAD-kinase	unknown	unknown	gnl\|CDD\|235317
NZ_LR738723.1\|WP_009909915.1\|984314_985070_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LR738723.1\|WP_002935234.1\|980724_981525_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225484
NZ_LR738723.1\|WP_002935232.1\|982146_982689_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LR738723.1\|WP_013730386.1\|978901_980062_+\|A/G-specific-adenine-glycosylase	unknown	unknown	gnl\|CDD\|224115
NZ_LR738723.1\|WP_029694363.1\|978274_978667_+\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|224961
NZ_LR738723.1\|WP_002935226.1\|985348_986116_+\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NZ_LR738723.1\|WP_002935225.1\|986321_986744_+\|galactose-6-phosphate-isomerase-subunit-LacA	unknown	unknown	gnl\|CDD\|181505
NZ_LR738723.1\|WP_002935224.1\|986770_987286_+\|galactose-6-phosphate-isomerase-subunit-LacB	unknown	unknown	gnl\|CDD\|181506
NZ_LR738723.1\|WP_002935238.1\|974825_976562_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_LR738723.1\|WP_002935231.1\|982914_983946_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271189
NZ_LR738723.1\|WP_012027041.1\|972938_973832_+\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NZ_LR738723.1\|WP_002935233.1\|981656_982127_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LR738723.1\|WP_012028207.1\|968564_969680_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
NZ_LR738723.1\|WP_002935223.1\|987295_988228_+\|tagatose-6-phosphate-kinase	unknown	unknown	gnl\|CDD\|237405
NZ_LR738723.1\|WP_002935243.1\|970812_971379_-\|CYTH-domain-containing-protein	unknown	unknown	gnl\|CDD\|143627
NZ_LR738723.1\|WP_074389317.1\|976548_978291_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_LR738723.1\|WP_002935239.1\|973849_974824_+\|phosphate-acetyltransferase	unknown	unknown	gnl\|CDD\|236609
NZ_LR738723.1\|WP_012775438.1\|969690_970668_-\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|235039
NZ_LR738723.1\|WP_002935242.1\|971465_972137_+\|GTP-pyrophosphokinase-family-protein	unknown	unknown	gnl\|CDD\|225232

Protein	Function_ID	Function_description	E-value
NZ_LR738723.1\|WP_032500985.1\|972111_972939_+\|NAD-kinase	gnl\|CDD\|235317	PRK04885, ppnK, inorganic polyphosphate/ATP-NAD kinase; Provisional.	2.0738e-172
NZ_LR738723.1\|WP_002935234.1\|980724_981525_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225484	COG2932, COG2932, Predicted transcriptional regulator [Transcription].	2.87242e-15
NZ_LR738723.1\|WP_013730386.1\|978901_980062_+\|A/G-specific-adenine-glycosylase	gnl\|CDD\|224115	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair].	1.46415e-147
NZ_LR738723.1\|WP_029694363.1\|978274_978667_+\|PaaI-family-thioesterase	gnl\|CDD\|224961	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis, transport, and catabolism].	4.99657e-25
NZ_LR738723.1\|WP_002935224.1\|986770_987286_+\|galactose-6-phosphate-isomerase-subunit-LacB	gnl\|CDD\|181506	PRK08622, PRK08622, galactose-6-phosphate isomerase subunit LacB; Reviewed.	8.87204e-126
NZ_LR738723.1\|WP_002935225.1\|986321_986744_+\|galactose-6-phosphate-isomerase-subunit-LacA	gnl\|CDD\|181505	PRK08621, PRK08621, galactose-6-phosphate isomerase subunit LacA; Reviewed.	6.97048e-84
NZ_LR738723.1\|WP_002935238.1\|974825_976562_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	5.29037e-130
NZ_LR738723.1\|WP_002935231.1\|982914_983946_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.90416e-22
NZ_LR738723.1\|WP_012027041.1\|972938_973832_+\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	5.18709e-91
NZ_LR738723.1\|WP_002935226.1\|985348_986116_+\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	2.73173e-82
NZ_LR738723.1\|WP_012028207.1\|968564_969680_-\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	9.05394e-172
NZ_LR738723.1\|WP_002935223.1\|987295_988228_+\|tagatose-6-phosphate-kinase	gnl\|CDD\|237405	PRK13508, PRK13508, tagatose-6-phosphate kinase; Provisional.	2.46388e-176
NZ_LR738723.1\|WP_002935243.1\|970812_971379_-\|CYTH-domain-containing-protein	gnl\|CDD\|143627	cd07762, CYTH-like_Pase_1, Uncharacterized subgroup 1 of the CYTH-like superfamily. Enzymes belonging to the CYTH-like (also known as triphosphate tunnel metalloenzyme (TTM)-like) superfamily hydrolyze triphosphate-containing substrates, require metal cations as cofactors, and have a unique active site located at the center of an eight-stranded antiparallel beta barrel tunnel (the triphosphate tunnel). The name CYTH originated from the gene designation for bacterial class IV adenylyl cyclases (CyaB) and from thiamine triphosphatase. Class IV adenylate cyclases catalyze the conversion of ATP to 3',5'-cyclic AMP (cAMP) and PPi. Thiamine triphosphatase is a soluble cytosolic enzyme which converts thiamine triphosphate to thiamine diphosphate. This domain superfamily also contains RNA triphosphatases, membrane-associated polyphosphate polymerases, tripolyphosphatases, nucleoside triphosphatases, nucleoside tetraphosphatases and other proteins with unknown functions. Proteins of this subgroup are of bacterial origin and have not been characterized.	3.30094e-69
NZ_LR738723.1\|WP_074389317.1\|976548_978291_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.53539e-168
NZ_LR738723.1\|WP_002935239.1\|973849_974824_+\|phosphate-acetyltransferase	gnl\|CDD\|236609	PRK09653, eutD, phosphotransacetylase.	0
NZ_LR738723.1\|WP_012775438.1\|969690_970668_-\|ribose-phosphate-diphosphokinase	gnl\|CDD\|235039	PRK02458, PRK02458, ribose-phosphate pyrophosphokinase; Provisional.	0
NZ_LR738723.1\|WP_002935242.1\|971465_972137_+\|GTP-pyrophosphokinase-family-protein	gnl\|CDD\|225232	COG2357, COG2357, PpGpp synthetase catalytic domain [General function prediction only].	5.5421e-94

>NZ_LR738723.1|WP_029694363.1|978274_978667_+|PaaI-family-thioesterase
MKVLDKLNLQPITVLDDYQATMLNEKEVLLTTKVTEKSLNPYGMAHGGFLFTLADSVAGLTTVVGGSYSVTLQSNIHYMKAAKLGDTLSVTGSCTHDGSRTKVVEVKIKNQDKQLLASASFTMFVTGKVE
>NZ_LR738723.1|WP_074389317.1|976548_978291_+|ABC-transporter-ATP-binding-protein
MKQSSFKELVRLVLGQPFQMYLMLVGTLVQVLLTVYLPILIGQAVDAVLIADGQVLLGIIGKMVMVILLNTLVQWYLPLVTNRLVYGMVADLREQVYVKLHQMPLSYLDRQSVGDLVARFSSDSEQLTNGLLMIFNQFFIGILTIFLTIFTMARLDLTMMLVVVALTPVSLLVARYIAKKSYGYYRKQTQARGKQSQLLEESISQLTLVQSFNAQEQFTQGFQVVNDQYATYSQQAIFASSTVNPSTRFINAIIYALLAGLGALRIMAGQFTVGSLTTFLNYASQYSKPFNDISSVLSELQSALACADRLFAILALDSIDDQAERKIDSEELKGAISFDNVSFSYSPERSLIEHLDIDVEAGQKVAIVGPTGAGKSTMINLLMRFYDVTAGQIVLDGVPIRQYSREDLRRQIGMVLQETWIKSGTIHDNIAYGYPNATRELVIEAAKAANADFFIRQLPQGYDTVLADGGEGLSQGQRQLLSIARVFVKIPKILILDEATSSIDTRTEILVQEAFAKLMEGRTSFIIAHRLSTIQSADLILVMVDGKIVEQGNHEALMAEQGVYYQMQTSQQTEEDESVR
>NZ_LR738723.1|WP_002935238.1|974825_976562_+|ABC-transporter-ATP-binding-protein
MKFLSRYFKDYIKESILGPVFKLLEACFELLVPLIIAYIVDTIIPNGSQGNLVAMLFLLVGLACIGIIVSLIAQYYSAKAAVGVTKELTNDLYQKVLSLPKSSRDILSSSSLLTRLTSDTLQIQTGINTFLRLFLRAPIVVFGSLIMAFYISPSLSAYFLEMIILLIFIVTVISVMTSRIYQSMRKELDGLVGQVRETVTGWRVIRAFGQREREIKAFQGINQIYKKQQLQAGFWSSLLSPLTFLVVNGTLLILIWQGNIAISHNLLEQGMLVALINYLLQILVELVKMIMVVSTLNQTYISAQRIQEVFDQTSEDVESSLPKVVSEDKEIIFSVRHISFSYPKSAEESLSDIAFDLRKGQFMGIIGGTGSGKSTLVDLLQALYSVPTNQLSLFIDGKSPKNLKEWRQQIAIVPQQAQLFAGTVRSNLSLGLESVLDSELWAALEIAQAKSFIEDKGGLDSPVEAFGKNFSGGQRQRLTIARAILQKAPILVLDDATSALDYLTESRLLAAIRRAFPAQTLIMVSQRTNSLRTADQILVFDQGRQVGLGRHEDLLRSSAIYQEIDQSQHREEDSHETI
>NZ_LR738723.1|WP_002935239.1|973849_974824_+|phosphate-acetyltransferase
MKIFEQLATKLEGKKVRIVLPEGEEPRILQATKRLVNESDVVPVLLGNPDRIKIYLDIEGITEGFEIIDPAHYDRYDEMVAALVERRKGKVSEEQAHELLKDVNYFGVMLVYMGVVEGMVSGAIHSTASTVRPALQIIKTEPGVSKTSGAFLMVKGEERYIFGDCAINIDPDAQTLAEIAINSARTAKMFGIDPKVAMLSYSTKGSGAGPKVDKVVEATKIAQKLRPELDLDGELQFDAAFVPTTGKLKAPGSSVAGQATVFIFPGISAGNIGYKIAERMGGFAAVGPVLQGLNQPVNDLSRGCNPDDVYNLTLITAVQALEHR
>NZ_LR738723.1|WP_012027041.1|972938_973832_+|RluA-family-pseudouridine-synthase
MRFEFIADQHTKIKTFLKKHGVSKGLLAKIKYTGGNIWVNDIEQNATYLLDIGDRVTIDIPAEEDLTGSLKPIFFPLDIVYEDDHFLAINKPVGYASIPSALHSSTIANFVKGYLIEQNYENKQVHIVTRLDRDTSGVMLFAKHGYAHARLDKQLQAKLIHKRYYALVKGNGQLEETGDIIAPIGRPEDSIITRCVTKNGKYAHTSYRVVQSWGDIHLVDIQLHTGRTHQIRVHFSHIGFPLLGDDMYGGSLECGIERQALHCHNLAFDNPFSAERIDLEAPLPEDFQAVINQLISK
>NZ_LR738723.1|WP_032500985.1|972111_972939_+|NAD-kinase
MIQMKNTGRKKIALLASRNPKSEAVSKELWTKLKEANFILTPKNPDIVISIGGDGMLLSAFHKYEKLIDRVRFVGIHTGHLGFYTDYRDFEVDKLIENLKLDTGARVSYPILNVKVKMTDGRIVEARALNEATVKRLSKTMVADIIINNVPFERFRGDGISVSTPTGSTAYNKSLGGAVLHPTIEALQIAEVASLNNRVYRTLGSSVVVPKKDKIVIEPKHSDRYSIAIDNKTFVYDSIESIEYQIDNSKIHFVATPSHTSFWNRVKDAFIGEVE
>NZ_LR738723.1|WP_002935242.1|971465_972137_+|GTP-pyrophosphokinase-family-protein
MDFNWEEFLDPYIQTVGELKIKLRGIRKQYRKANRHSPIEFVTGRVKPIESIKEKMALRHIKLENLAQDMQDIAGLRIMVQFVDDIEEVLAILRKRKDMQIVHERDYINNMKASGYRSYHVVIEYPVDTINGNETVLAEIQIRTLSMNFWATIEHSLNYKYKGNFPEEIKKRLEVTAKIAYELDEEMRKIRNDIQEAQALFDPAYRKLNDGVGNSDDTDEEYR
>NZ_LR738723.1|WP_002935243.1|970812_971379_-|CYTH-domain-containing-protein
MKNHLEIEYKTLLTKSEYKRLLTDFSDVSPILQTNHYIDTPDLDMKNHRFSLRIRTFEDSAELTLKIPQEVGNQEYNQVLDIQTAHDLLENFQLPAGQISDIISATEIPLDKLAVWGILTTKRYEKQTSIGLMALDENDYVGQKDYELEVEVTDADAGKILFDEFLKKKSIQFKYASSKVARTAAHMK
>NZ_LR738723.1|WP_012775438.1|969690_970668_-|ribose-phosphate-diphosphokinase
MVQPLGEHNIKLFSLNSNRDIAEKIADSAGIPLGKLSSRQFSDGEIQINIEESVRGVDVYIIQSTSYPVNNHLWELLIMIDACKRASANTITAVIPYFGYARQDRTASPREPITAKLVANMLVKAGVDRVLTLDLHASQIQGFFDIPVDNLLTEPLFAAYYMEKGLCGEDVVIVSPKNSGIKRARNIAEFLNAPIAIIDYAQDDSERSEGYIIGDVAGKKAILVDDILNTGRTFSQASKIVQEGGATEIYAVASHGLFAGTAAQLLDEAPIKEILVTDSVASKEQHPKNIAFLTASDLIADAIHRIQEHQPLSPLFKFTSPEKEN
>NZ_LR738723.1|WP_012028207.1|968564_969680_-|cysteine-desulfurase
MIYLDNAATTALSPTALQRMMEVAQENYGNPSSIHQSGRKANQCLRQSRQEIAQILSASPEQIIFTSGGSEADTLAIQGYALAHQSKGKHLITTAIEHHAVLHTMQYLEDRFGFEVTYIQPVNQVITAQQILDALRPDTILVSVMFANNETGQLLPIKEIGELLADHQAVFHVDAVQAIGKIAISPSDYGIDLLAASAHKFHGPKGMGFLYSKVHKFDSLIHGGKQEQQHRAGTENLPAIAAMATALTEQYESLDTHHQHVSELRQHIIEGLSGLDYYLNQAGPHLPHVLNIGFLGKLNEQLLMQLDLAGIAVSSGSACTAGVVQNSHVLEAMYGKDSHRLKESIRISLSEINTKEEIDTLIIELKKILGG
>NZ_LR738723.1|WP_013730386.1|978901_980062_+|A/G-specific-adenine-glycosylase
MLDLKEYGIEMWPEEKIQAFRKALLDWYDANKRDLPWRRTKDPYAIWVSEIMLQQTRVDTVIPYYERFLHYLPTISDLAQAPEEVILKLWEGLGYYSRVRNMQKAAQQMVEDFDGQFPTTHAAISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLSRLFEVDYDIGLPANRKIFQAMMELLIDPERPGDFNQALMDLGSDIESPVNPRPQDSPVKAFSAAYLNGTMDKYPIKAPKKKPIPVAYQGFLIRNKDNQFLLEKNNEAGLLSGFWSFPLLEKGAIVEKQVSLFEVAEEVVQPDIRQSFTELYGLTVDWQEQEFGIVQHIFSHRKWQIEMVEGVAETLNLPESKELKWVSVEDFPTYPFAKPQQKMWENFIKEKEKQKS
>NZ_LR738723.1|WP_002935234.1|980724_981525_-|helix-turn-helix-transcriptional-regulator
MILGDILKEYRSKNKLSMDKFAELSGLTKGYISMLEKNQHPKTKKALLPTMDTLEKVAKGMAISVGELIEQLDSNQDIALTITPSQFKLFQQPIHPEVQTLDNELKGDFHAQWLTFGQEQLAAMQTTSITPSASILHLDDYRERIDLPVPGKVSAGTGYWQDTDMNNLVSFYNDEIPDNQSYDTIAQVVGDSMAPHIEDGDYLFIRLTPHIPLNTIGIFSVNGENFVKKFKGDYLQSLNSDYDDIYFSPEDDIRPIGQVVDIYSPD
>NZ_LR738723.1|WP_002935233.1|981656_982127_+|hypothetical-protein
MKRMTEISWNDIYKEWETYANHFGLTTPINTENLRDQKSKDFGKGSLITLDLLADYDTDSEKTAAIWVASFCRDLIQDYAYLLNGRAYLTVNQIYFQALKQFQSGAVIWSKPLTRLQPKLFVSYRLLENLDLSHYSCVVELAMLQASMVRTQILEK
>NZ_LR738723.1|WP_002935232.1|982146_982689_+|hypothetical-protein
MFNLLNKKAEVSKVAEYWNDTLIERGILSADELLEGKCWRCKSSHGVAVCQIVSSKWSKDASLANQMVLCLSCQHEKPNVADTEIVWQWLEVENDERYWTLQGMAEYEKMYKKSVLQELWDMGIRDGEEVETLVNKVTSLSRKNDIVLNRATLAGLFRCEIEQMRRKAFLNWTGIFKLVS
>NZ_LR738723.1|WP_002935231.1|982914_983946_-|tyrosine-type-recombinase/integrase
MATITKRGNSYRATVSLYKKGEYKRETKTFSNRKDAELWTLEMELEKGRGKNIAERSTLFPDFYRNWVHTVKKTDVREATFINYKRTLVIVDDLFDGIQLKHLDDLVMQKKIDQYAETHSKKTVKELVLKIRGSLKYAYARGLISNDFGHLLKSKGQEQPKSITEFKKLRQYCLSHTENEFNVLVALALETVARRGELLGIKKEDIFEYGIKILRSISPTNDDTRLKTKYSKRDISINEDVYQAVTKLAQTKEGYIFDWNGFKQASQLQKLLKQLGLTKTTFHGLRDTHASFLFSKDISLDYISRHLGHNSILTTQQYYLELMPEKKHQQDADALSLLNDLSL
>NZ_LR738723.1|WP_009909915.1|984314_985070_-|hypothetical-protein
MALGNVEKDTEGWIELINQYLQYCIEIGLSPYTQATYKVALTKVLGVSSTNFIATQPRTRANRMNNRVLHKDYRLSNKNNDYWHKVVTSTGLRKSELIHVTGDALQRGRDGRWYLNLAGHKHHTKGRRDRWSPIMATSQEEEEWLVAIFQRAGEKKVFHVPKDLILDDFDGKKVPTALKSHKYPTEYAERVYRSVAREISKIRNRKEVIHLRKELVGISLNRKACKIVIKTLGHNRPEEFPRSYAYILLKR
>NZ_LR738723.1|WP_002935226.1|985348_986116_+|DeoR/GlpR-transcriptional-regulator
MNKRERLEEITRLVNKKGTVRISEIVELLNVTDMTVRRDFIELEEQGVLTKIHGGARSNKAFQYREYSHSEKHIQNKEAKQEIAERAAQLIEDGDTVFLGPGTTVAFLAEAIKNSRLTVITNCMPVFTILSQKKTEEFQVFLLGGEYRQVTESFVGEITNTSLEKMRFSKIFFSGNGLKGTDVMTSTLAEAYTQNIAIKHSLEKYLLLDASKIGKDDFTSFCDLHDVTALVTDMNAKDENYQLLSKHIEIITTKL
>NZ_LR738723.1|WP_002935225.1|986321_986744_+|galactose-6-phosphate-isomerase-subunit-LacA
MTIIIGADPAGSKLKDVIKDYLLEKSYDFKDVSDGSDFVDTTLAVVAEVNQQEGNLGIVIDAYGVGPFMTATKVKGMIAAEVSDERSAYMTRGHNNSRIITIGSEIVGEGIAKNIVKGFVEGEYDGGRHQIRVDMLNKMC
>NZ_LR738723.1|WP_002935224.1|986770_987286_+|galactose-6-phosphate-isomerase-subunit-LacB
MKIAIGCDHIVTYEKIAVVDYLKNQGYEVLDFGTYDNVRTHYPIFGKKVGEAVASGQADLGICICGTGVGINNAVNKVPGVRSALVRDMTSALYAKEELNANVIGFGGKITGELLMCDIIEAFIKAEYKPTEANKRLIEKIAAVETLNQEQANPEFFTEFLEKWDRGEYQD
>NZ_LR738723.1|WP_002935223.1|987295_988228_+|tagatose-6-phosphate-kinase
MILTITLNPSVDIAYQLDTFHLDTVNRVEKVQKTAGGKGLNVTRVLKQIGEDVVATGFIGGEIGSYVKKQLTRNDIKNSFVEIGNETRNCIAVLHDGQQTEILEQGPTIQEHEALNFIEHLEIILNNVDVVVISGSLPKGLASNYYVQLVELCKKFGIAVVLDCSGEALKNVLESQQKPTVIKPNTEELSQLIGKEVTDDIQELKSVLSGQLFQGIDWIVVSLGAQGAFAKHNDKFYRVRIPKIKVVNPVGSGDSTVAGIAAGLVHALPDAELLKNANVLGMLNAQEEQTGYVNLENAESLYSQIEVEEV

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Click the colored protein region to show detailed information

Crispr_ID: NZ_LR738723_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LR738723_3

2268914-2269014

Orphan

Consensus_repeat	Method
ATGTAGTAGTTCTTTTCAAAAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LR738723_3

>merge|NZ_LR738723|3|2268914-2269014|CRISPRCasFinder
ATGTAGTAGTTCTTTTCAAAAAAGAATAACTACACTGTCAAACCCTTGTCCCGTAAGGGTTTAGCCACTTTGTAGTGAATGTAGTCGTTCTTTTCAAAAAA

>NZ_LR738723|3|2|2268914-2269014|CRISPRCasFinder
ATGTAGTAGTTCTTTTCAAAAAA	GAATAACTACACTGTCAAACCCTTGTCCCGTAAGGGTTTAGCCACTTTGTAGTGA
ATGTAGTCGTTCTTTTCAAAAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LR738723.1\|WP_012775413.1\|2263931_2265215_-\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NZ_LR738723.1\|WP_074389573.1\|2269187_2270624_-\|DNA-primase	unknown	unknown	gnl\|CDD\|273716
NZ_LR738723.1\|WP_074389570.1\|2266885_2267281_-\|DUF1492-domain-containing-protein	unknown	unknown	gnl\|CDD\|273725
NZ_LR738723.1\|WP_171840765.1\|2271566_2271713_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366308
NZ_LR738723.1\|WP_074389597.1\|2271973_2272312_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LR738723.1\|WP_162841090.1\|2268699_2268873_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LR738723.1\|WP_074403919.1\|2270686_2271565_-\|primase-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|214926
NZ_LR738723.1\|WP_074389566.1\|2260792_2261635_-\|energy-coupling-factor-transporter-ATPase	unknown	unknown	gnl\|CDD\|184208
NZ_LR738723.1\|WP_074389577.1\|2271699_2271984_-\|transcriptional-regulator	unknown	unknown	unknown
NZ_LR738723.1\|WP_074389584.1\|2274148_2274355_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238045
NZ_LR738723.1\|WP_074389571.1\|2268136_2268679_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LR738723.1\|WP_074389568.1\|2261610_2262447_-\|energy-coupling-factor-transporter-ATPase	unknown	unknown	gnl\|CDD\|184209
NZ_LR738723.1\|WP_032538261.1\|2274393_2274588_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_LR738723.1\|WP_029174017.1\|2274762_2275515_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|119397
NZ_LR738723.1\|WP_012028045.1\|2262443_2262983_-\|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	unknown	unknown	gnl\|CDD\|273139
NZ_LR738723.1\|WP_044752435.1\|2267237_2267657_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379583
NZ_LR738723.1\|WP_023371884.1\|2262992_2263850_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|224343
NZ_LR738723.1\|WP_012028048.1\|2265211_2266465_-\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NZ_LR738723.1\|WP_074389580.1\|2272652_2273042_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LR738723.1\|WP_074389582.1\|2273510_2274137_-\|Rha-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226172

Protein	Function_ID	Function_description	E-value
NZ_LR738723.1\|WP_012775413.1\|2263931_2265215_-\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	4.36191e-68
NZ_LR738723.1\|WP_074389573.1\|2269187_2270624_-\|DNA-primase	gnl\|CDD\|273716	TIGR01613, putative_primase, phage/plasmid primase, P4 family, C-terminal domain. This model represents a clade within a larger family of proteins from viruses of bacteria and animals. Members of this family are found in phage and plasmids of bacteria and archaea only. The model describes a domain of about 300 residues, found generally toward the protein C-terminus. [DNA metabolism, DNA replication, recombination, and repair, Mobile and extrachromosomal element functions, Prophage functions].	8.2033e-69
NZ_LR738723.1\|WP_074389568.1\|2261610_2262447_-\|energy-coupling-factor-transporter-ATPase	gnl\|CDD\|184209	PRK13650, cbiO, energy-coupling factor transporter ATPase.	0
NZ_LR738723.1\|WP_074389584.1\|2274148_2274355_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	7.07894e-10
NZ_LR738723.1\|WP_023371884.1\|2262992_2263850_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|224343	COG1426, COG1426, Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown].	3.15604e-30
NZ_LR738723.1\|WP_074403919.1\|2270686_2271565_-\|primase-C-terminal-domain-containing-protein	gnl\|CDD\|214926	smart00942, PriCT_1, Primase C terminal 1 (PriCT-1). This alpha helical domain is found at the C terminal of primases.	5.40142e-17
NZ_LR738723.1\|WP_074389566.1\|2260792_2261635_-\|energy-coupling-factor-transporter-ATPase	gnl\|CDD\|184208	PRK13649, cbiO, energy-coupling factor transporter ATPase.	0
NZ_LR738723.1\|WP_171840765.1\|2271566_2271713_-\|hypothetical-protein	gnl\|CDD\|366308	pfam00792, PI3K_C2, Phosphoinositide 3-kinase C2. Phosphoinositide 3-kinase region postulated to contain a C2 domain. Outlier of pfam00168 family.	0.00837519
NZ_LR738723.1\|WP_032538261.1\|2274393_2274588_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	4.03122e-16
NZ_LR738723.1\|WP_029174017.1\|2274762_2275515_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|119397	cd06529, S24_LexA-like, Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the repressor of genes in the cellular SOS response to DNA damage; MucA and the related UmuD proteins, which are lesion-bypass DNA polymerases, induced in response to mitogenic DNA damage; RulA, a component of the rulAB locus that confers resistance to UV, and RuvA, which is a component of the RuvABC resolvasome that catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. The LexA-like proteins contain two-domains: an N-terminal DNA binding domain and a C-terminal domain (CTD) that provides LexA dimerization as well as cleavage activity. They undergo autolysis, cleaving at an Ala-Gly or a Cys-Gly bond, separating the DNA-binding domain from the rest of the protein. In the presence of single-stranded DNA, the LexA, UmuD and MucA proteins interact with RecA, activating self cleavage, thus either derepressing transcription in the case of LexA or activating the lesion-bypass polymerase in the case of UmuD and MucA. The LexA proteins are serine proteases that carry out catalysis using a serine/lysine dyad instead of the prototypical serine/histidine/aspartic acid triad found in most serine proteases. LexA sequence homologs are found in almost all of the bacterial genomes sequenced to date, covering a large number of phyla, suggesting both, an ancient origin and a widespread distribution of lexA and the SOS response.	1.26451e-13
NZ_LR738723.1\|WP_012028045.1\|2262443_2262983_-\|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	gnl\|CDD\|273139	TIGR00560, pgsA, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. Alternate names: phosphatidylglycerophosphate synthase; glycerophosphate phosphatidyltransferase; PGP synthase. A number of related enzymes are quite similar in both sequence and catalytic activity, including Saccharamyces cerevisiae YDL142c, now known to be a cardiolipin synthase. There may be problems with incorrect transitive annotation of near homologs as authentic CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis].	4.16121e-43
NZ_LR738723.1\|WP_044752435.1\|2267237_2267657_-\|hypothetical-protein	gnl\|CDD\|379583	pfam14362, DUF4407, Domain of unknown function (DUF4407). This family of proteins is found in bacteria. Proteins in this family are typically between 366 and 597 amino acids in length. There is a single completely conserved residue R that may be functionally important.	0.0032005
NZ_LR738723.1\|WP_074389570.1\|2266885_2267281_-\|DUF1492-domain-containing-protein	gnl\|CDD\|273725	TIGR01637, Putative_autolysin_regulatory_protein_ArpU, phage transcriptional regulator, ArpU family. This model represents a family of phage proteins, including ArpU, called a putative autolysin regulatory protein. ArpU was described as a regulator of cellular muramidase-2 of Enterococcus hirae but appears to have been cloned from a prophage. This family appears related to the RinA family of bacteriophage transcriptional activators and to some sporulation-specific sigma factors. We propose that this is a phage transcriptional activator family. [Mobile and extrachromosomal element functions, Prophage functions, Regulatory functions, DNA interactions].	1.16679e-08
NZ_LR738723.1\|WP_012028048.1\|2265211_2266465_-\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	1.26943e-47
NZ_LR738723.1\|WP_074389582.1\|2273510_2274137_-\|Rha-family-transcriptional-regulator	gnl\|CDD\|226172	COG3646, COG3646, Uncharacterized phage-encoded protein [Function unknown].	1.47271e-31

>NZ_LR738723.1|WP_162841090.1|2268699_2268873_-|hypothetical-protein
MKIKLLKNLAKESPQDFEERVNEFMATVEVVDVKIAMASAGYSDSFGTVTHILVLYK
>NZ_LR738723.1|WP_074389571.1|2268136_2268679_-|hypothetical-protein
MTLKTISDTPNTFTFNYTFKDFDTAQVAGHALIGYMTGTFEQPAIEVHYKSDKVGGDYNRLAVEYVADTELTEVFQRICDSFQDYYTDPEKKLEDQYRLERTEQLKQSEDFDSLLKKVVAYELELIDYGERLLSDDPIPMDSETGYSTLDLIGAKGVGLLKSLDEDNEYSGLAYYNAEAE
>NZ_LR738723.1|WP_044752435.1|2267237_2267657_-|hypothetical-protein
MDLKQLAKFEKLVQSKKREIEALRAGIVNTPDYQSQRVKHSKQNAAEDQVVKRIEKIEQLETELAQLYADYSELSARIDAITDPVASLIMRLKYINGYPWPIIKRTLPYYSQSSLYDYHKKGLEELEQTTSKKKTERVS
>NZ_LR738723.1|WP_074389570.1|2266885_2267281_-|DUF1492-domain-containing-protein
MSKQLAKRKLKEFHRWCRISNLFHEQTESFDNWLIPPLEFDPEDYKGRIYDWQREAPEEVNEIIKAVNAIARPRHRAVLIMSYILPEKIRSAEQAQQLGIKSSTYYLAKNKALEEFASQYRSGILERYRGG
>NZ_LR738723.1|WP_012028048.1|2265211_2266465_-|insulinase-family-protein
MKLQEGVDLHFIDTDQFTTNRIRIRFAAEMSEATVAGRVLVANIFEMGNQEFQTAQAVRRRLAELYGAQFSTSVSKRGRVHCVDVTISYVSPRHLPENEDITVEILDFLYTCIFRPLKKGRGFDSQIFEVEKTNLINFLQSEIEDNFYHVDVEMSKLFYKDPSLQIPRVGRLDLVEKETAESTFQIYRNMLRMDKIDIFVLGKVDREQVKRKLEDFGFTYRNPKLELEYHQEYSNITQEKIERKQARQSILELAYHLQVVYNDVNYPALMVFNGLLGAFSHSKLFMNVREKESLAYTIGSQVSIFSGMLKVYAGISRENRLRVMKLISKQLLDLKCGKFTEEELELTKNMLIHSATLAQDRQNNLIEQVYNQVTLGNRNLSWLDWIEAIKSVSIDDVIQVGQMINLQAVYFMEGTEE
>NZ_LR738723.1|WP_012775413.1|2263931_2265215_-|insulinase-family-protein
MKLVEKKYPYMKESVFYGKVDNGLTVILLPKVDFHETYGILTTNFGGIHTRFTLANGNSVVYPAGIAHFLEHKLFETENEEDIMNEFAKLGASANAYTSFRQTSYLFSTTQKVLESLSLLQSFVREPYFTEDNVEREQGIIEQEIEMYQDDADYRLFTGILSSLYPESPLAYDIAGTVESIAAITADDLHENFDVFYHPSNMNLFVIGNFDLEAVWKQISSYQVAQMDNPAQSFELAGIQKLPIQEHLSEQFEVSTPKLAVGLRGNDEVDKETIQKYRLSLQFLFAMLFGWTSKRYQQLYEQGKIDSSFQFQLEVTPEYHYLIISGDTQEPITLSSILMKALRKFEDDADVTEDHLQLLKNEMYGDFIRSLNSLEFTASHFVSQYSEYENVFDIPQMIQSLQLDDIREAGRRFIDHCDMTDFTIFPK
>NZ_LR738723.1|WP_023371884.1|2262992_2263850_-|helix-turn-helix-domain-containing-protein
MRQKSIGEVLRTAREGRGWTFVDLQRITKIQAKYLQALEYNDFDFIANSDVVQSILKAYAEALELDADVLLDAYETNSLVKYYEDGEEELRSSELKRSYKVRKRKKNSYLPLIYLLLATGLIIIFVTYIVHSRLKNRASITPTTTSYSIVEQSVSEASSGTETSSTEQAQSNSTSSSSSATENVTISGSGSNIVATLKTVTYPVEVTVTAKNTTSWISLSDTLLEGGVTLTPDNPTVTTTIEEGVTSTTLILGVVKGVEVSVGGQKLELSALTADTGSITINFEQ
>NZ_LR738723.1|WP_012028045.1|2262443_2262983_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase
MKKENIPNALTIGRILVIPIFILLLTVWNSTISHVLAALIFALASITDYLDGYLARKWQVVTNFGKFADPMADKILVMTAFIMLVELGFAPAWVVAIIICRELAVTGLRLLLVENGGTVLAAAMPGKIKTFSQMFAVIFLLLHWNVVGQITLYIALFFTLYSGYDYFKGASFLFKDTFK
>NZ_LR738723.1|WP_074389568.1|2261610_2262447_-|energy-coupling-factor-transporter-ATPase
MMNIIEVKNLKYKYNQEDEQYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGDIYIDGDALTIDNVWDKRRLIGMVFQNPDNQFVGATVEDDVAFGLENQGIPLEEMRSRVDEALELVGMTDFKTREPARLSGGQKQRVAIAGVVALRPKIIILDEATSMLDPEGRLDLIKIVREIQERHGMTVISITHDLDEVALSDRVIVMKNGQVESISTPNELFMREDLVDLDLDRPFTTELASSLRQTGLDLPLRYFTEEELEETLWELISKK
>NZ_LR738723.1|WP_074389566.1|2260792_2261635_-|energy-coupling-factor-transporter-ATPase
MGIDLQEVSYTYQAGTPFEGRALFGVDLEIVDGSYTALIGHTGSGKSTILQLLNGLNVPTEGRVVIDDVVITATSENKDIKQVRKKVGLVFQFPESQVFDETVLKDVAFGPQNFGVSQEEAETIAREKLALVGIDESLFERSPFELSGGQMRRVAIAGILAMEPSILVLDEPTAGLDPAGRQELMDIFKKLHESGMTIVLVTHLMDDVANYANFVYIMEKGKLVRSGKPVDIFQEVDFLESIQLGVPKITKFAANLERRGFVFERLPITIEEFTGMVTHG
>NZ_LR738723.1|WP_074389573.1|2269187_2270624_-|DNA-primase
MKELYNTLYELGAIWREEHQYTVNEGKKNEKVVIPIPEVSTVAKYLRQVCHFAFISVGDSSDKSPLYLYHYDKGIYTDSVDLFNKLCAKFDSRLKPRAWADIRAFIRTTTRIYKPFSDHTRIPVANGVFNLKTKQLEPFSPNFVITSKIRTAYNGAARKPILDSWFDFEQWLDIIACGDSEIYALLWQIMNEAINPNRTRGKLAILLGDGNNGKGTFQSLLMNLIGADKVATLRPDQFEGHNLASLSGKVCNIGDDISNRYIDEVSDLMSIVTGDTVTINPKHQQPFELSLKLFCLFSANELPRVRNKSQGWYRRLCIVPFKADFNGQKERPEIKNIFLKDTELLEWVLFKILNMPAFDKFIEPEAVAKEIDSYKKENDYLYAFVTDDYTERELHLIERVPLKWIKEEYRTFLAENDLSAHIPYSFGKDLVRILRVHTGGKYSLRQGRLKKKEAEVFPYPLTIAEYTEYPLRLVEKDE
>NZ_LR738723.1|WP_074403919.1|2270686_2271565_-|primase-C-terminal-domain-containing-protein
MAIYEARGFQNNLVYPFDRLEPFEYIAQFRPMKVPEGADIDQFKRTQAPYCISGKVTADKKGTHRRNNSSLVYRDLVFLDYDELEASVDFPRIVSEALSDYSYIIYPTIKHTAKKPRYRLVVKPSHKMKETTYRATVQEIADKIGLPFDMASLTWSQLQGLPVTTGELEEYQKIIHRGSDYPIQAVLDKQPTKKAVTTTYTPRPSGHRSITMRVIDTLFNGFGDEGGRNVAVTRFVGLLVGKGVNCDIPTAWELTQIANSVTADPLPVDELEATFESIVKTEIRKRGLGVSN
>NZ_LR738723.1|WP_171840765.1|2271566_2271713_-|hypothetical-protein
MARYSIHPADSGGHYHDIKLYKDRSPTFEQVKEQQRLKKLKKKRRKGQ
>NZ_LR738723.1|WP_074389577.1|2271699_2271984_-|transcriptional-regulator
MKLELTAQSEIDLKTGILELIKNYLEAREMVKPRVTGLITAQQLKDELGIKAKTLKRWEDNGLRRYQPPLEDTRKIFYRVSDILIFLGVENGKV
>NZ_LR738723.1|WP_074389597.1|2271973_2272312_-|hypothetical-protein
MTENRLPPHLYKVFKLLPLGIDLPITASDIEKLTGLDIRTIRENIRQLIVDYGIPVCGGRDNKQGGYYIPQNEVERLAGVIPLQRQYDQEHKRIHALLTADLQDWRKYRDEA
>NZ_LR738723.1|WP_074389580.1|2272652_2273042_-|hypothetical-protein
MKNNNRETIIHFENSSKEYSPVKNAVSEELETVIRKVYQLDHATGWTLHYLTDIMMNHFHEDVARVTNGDLTPIERSLNGITSRVENTRMVLLKAGYEDKIEVGNPMWYLKLILQDFEQMKKEMKKCKK
>NZ_LR738723.1|WP_074389582.1|2273510_2274137_-|Rha-family-transcriptional-regulator
MELVYMDGRKEPYTLSSIISDNAEITHHAVKEQIRKHLAELEKFGKVAFKMTPLESGQSKRDYILNEQQATLLITFLRNTAPVIAFKSALVKAFFEMRDEVAEFRYQRTLEKPKRKALHEAIETWQEAPKHAHSTVTNLLLKGTTGMNKRQLVAHRGGFNGVDSLTSQELIRYQALEDMAIAMINLGMTYQEIKNMVFRPLKNAHQGA
>NZ_LR738723.1|WP_074389584.1|2274148_2274355_-|helix-turn-helix-domain-containing-protein
MELGERIKVIRVSLGETMEQFGQRFNTSKGTVNNWEKGRNAPNKANLKKIADLSDNPREFIALYLTRV
>NZ_LR738723.1|WP_032538261.1|2274393_2274588_-|helix-turn-helix-transcriptional-regulator
MSKYTLKALRANADMKQTEVAEKLGISTTTWSKWENKKRFPTVDQVEKISKLFNVAYDDIIFLP
>NZ_LR738723.1|WP_029174017.1|2274762_2275515_+|helix-turn-helix-domain-containing-protein
MSLGNKQIMAENIKRLLDMKGLNPRQMALALDFKYTTVLDWVNAKTYPRIDKIEIMANYFGVNKSDLIEEKSSVIPFSNFDPRQAILLSNYSKLDEANKNNLLKTSEQLLQNQNTSIVEELAITYEVKAVSRLAAGVGFGYDDNEIITVQVTNEPPKHDIASIVDGDSMTPNYHDGDVIYLRDKGISSYSGQVCAVVVDDKTYLKRVYTEATGLRLVSINKKYNDIVIDFPPSEDTHIKVFSVVGSDRVI

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LR738723_2	2.1\|978746\|28\|NZ_LR738723\|CRISPRCasFinder	978746-978773	28	NZ_CP043555	Vibrio cholerae strain RFB16 plasmid unnamed, complete sequence	6368-6395	6	0.786
NZ_LR738723_2	2.1\|978746\|28\|NZ_LR738723\|CRISPRCasFinder	978746-978773	28	NZ_CP040462	Enterococcus sp. M190262 plasmid pM190262, complete sequence	148656-148683	7	0.75

1. spacer 2.1|978746|28|NZ_LR738723|CRISPRCasFinder matches to NZ_CP043555 (Vibrio cholerae strain RFB16 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.786

caagtttccccaaacctttgtagaaatg	CRISPR spacer
ataccttccccaaaactttgtagaaatt	Protospacer
  * .********* ************

2. spacer 2.1|978746|28|NZ_LR738723|CRISPRCasFinder matches to NZ_CP040462 (Enterococcus sp. M190262 plasmid pM190262, complete sequence) position: , mismatch: 7, identity: 0.75

caagtttccccaaacctttgtagaaatg	CRISPR spacer
atttgttccgcaaaccgttgtagaaatg	Protospacer
     **** ****** ***********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

31438 : 41700

Microbacterium_phage(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_074389017.1\|31438_35158_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	8.6e-39	26.9
WP_011921648.1\|35160_36615_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-58	35.4
WP_012774882.1\|36670_37693_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A127KMF9	Cyanophage	1.3e-58	42.7
WP_011922533.1\|37689_38241_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.6e-26	38.5
WP_011921652.1\|38250_39798_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	2.6e-74	47.6
WP_014917169.1\|39923_41186_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_011921654.1\|41211_41700_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.7e-17	45.0

DBSCAN-SWA_2

125633 : 134866

Streptococcus_phage(80.0%)

integrase

attL 125210:125226|attR 134963:134979

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
125210:125226	attL	NA	NA	NA	NA
WP_074390445.1\|125633_126041_-	ArpU family transcriptional regulator	A0A1X9I5Y7	Streptococcus_phage	3.8e-65	94.8
WP_074392204.1\|126382_126958_-	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	1.4e-92	91.6
WP_171840772.1\|126978_127152_-	hypothetical protein	A0A1X9I5U0	Streptococcus_phage	1.2e-07	59.6
WP_156721189.1\|127465_128902_-	DNA primase	Q9AZI5	Lactococcus_phage	3.3e-63	38.0
WP_074403919.1\|128964_129843_-	primase C-terminal domain-containing protein	A0A1X9I6L2	Streptococcus_phage	6.4e-118	69.7
WP_044766582.1\|129977_130262_-	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	7.0e-42	89.4
WP_074390405.1\|130251_130590_-	hypothetical protein	A0A1X9I5Z6	Streptococcus_phage	3.3e-46	96.7
WP_074390406.1\|130806_131250_-	hypothetical protein	A0A1X9I5T7	Streptococcus_phage	2.7e-48	68.7
WP_074390407.1\|131721_132348_-	Rha family transcriptional regulator	A0A192Y918	Salmonella_phage	9.8e-12	30.8
WP_015647585.1\|132364_132565_-	transcriptional regulator	NA	NA	NA	NA
WP_074390408.1\|133720_134866_+\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	6.0e-84	43.6
134963:134979	attR	NA	NA	NA	NA

DBSCAN-SWA_3

982914 : 1019439

Leptospira_phage(40.0%)

transposase,integrase

attL 974804:974817|attR 992837:992850

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
974804:974817	attL	NA	NA	NA	NA
WP_002935231.1\|982914_983946_-\|integrase	tyrosine-type recombinase/integrase	E3W8I1	Leuconostoc_phage	5.9e-30	27.3
WP_009909915.1\|984314_985070_-	hypothetical protein	NA	NA	NA	NA
WP_002935226.1\|985348_986116_+	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_002935225.1\|986321_986744_+	galactose-6-phosphate isomerase subunit LacA	NA	NA	NA	NA
WP_002935224.1\|986770_987286_+	galactose-6-phosphate isomerase subunit LacB	NA	NA	NA	NA
WP_002935223.1\|987295_988228_+	tagatose-6-phosphate kinase	NA	NA	NA	NA
WP_002935222.1\|988229_989207_+	tagatose-bisphosphate aldolase	NA	NA	NA	NA
WP_014637028.1\|989394_990228_+	PRD domain-containing protein	NA	NA	NA	NA
WP_002935220.1\|990358_990676_+	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
WP_074389318.1\|990675_992355_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_002935218.1\|992589_993996_+	6-phospho-beta-galactosidase	NA	NA	NA	NA
992837:992850	attR	NA	NA	NA	NA
WP_002935214.1\|994062_994956_+	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_002935211.1\|996356_997361_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_002935210.1\|997597_998551_-\|transposase	IS30 family transposase	H7BWC8	unidentified_phage	1.1e-38	33.2
WP_002935208.1\|999531_1000296_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_002935207.1\|1000472_1001876_+	rhamnulokinase	NA	NA	NA	NA
WP_002935206.1\|1001986_1002625_+	L-fuculose-phosphate aldolase	NA	NA	NA	NA
WP_002935205.1\|1002636_1003077_+	fucose isomerase	NA	NA	NA	NA
WP_014637023.1\|1003069_1003501_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_002935202.1\|1003491_1003962_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_002935201.1\|1003984_1004758_+	PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC	NA	NA	NA	NA
WP_014637022.1\|1004754_1005555_+	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_002935195.1\|1005612_1007904_+	glycoside hydrolase family 95 protein	NA	NA	NA	NA
WP_002935191.1\|1008911_1010678_+	L-fucose isomerase	NA	NA	NA	NA
WP_145888480.1\|1011249_1012097_-\|transposase	IS630-like element ISSsu3 family transposase	S5VXX4	Leptospira_phage	1.1e-08	25.4
WP_002935185.1\|1013773_1014526_-\|transposase	transposase	NA	NA	NA	NA
WP_002935183.1\|1014736_1015087_-	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_002935182.1\|1015067_1015253_-	hypothetical protein	NA	NA	NA	NA
WP_014637021.1\|1017040_1017769_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_029694380.1\|1017953_1018544_-	recombinase family protein	M9Q1K0	Clostridium_phage	8.6e-10	28.0
WP_094122540.1\|1018592_1019439_+\|transposase	IS630 family transposase	S5VXX4	Leptospira_phage	1.5e-07	26.6

DBSCAN-SWA_4

1346946 : 1361596

Streptococcus_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012775042.1\|1346946_1347774_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	2.9e-152	100.0
WP_023370693.1\|1347960_1348860_+	cation transporter	M1Q1N9	Streptococcus_phage	5.7e-162	99.3
WP_002935368.1\|1348876_1349230_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.9e-60	100.0
WP_024381555.1\|1349213_1349720_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	3.7e-94	98.8
WP_014638089.1\|1349722_1350904_-	phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	9.2e-221	100.0
WP_023370699.1\|1350957_1351515_-	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	2.0e-93	95.1
WP_074389360.1\|1351514_1352606_-	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	9.2e-207	99.7
WP_024402772.1\|1352961_1353825_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.4e-157	99.0
WP_002935361.1\|1353826_1354144_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	3.1e-54	100.0
WP_024405505.1\|1354169_1355054_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.5e-154	99.0
WP_024379691.1\|1355050_1355689_-	dTMP kinase	M1PSC7	Streptococcus_phage	5.3e-114	99.1
WP_002935357.1\|1355863_1356730_+	YitT family protein	M1Q1P6	Streptococcus_phage	4.6e-153	99.7
WP_024405507.1\|1356766_1358038_-	toxic anion resistance protein	M1PLC8	Streptococcus_phage	4.3e-208	98.1
WP_011922194.1\|1358043_1358871_-	hypothetical protein	M1PFV6	Streptococcus_phage	1.0e-133	98.5
WP_074389404.1\|1359075_1360797_+\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_011922763.1\|1360939_1361596_-	CBS domain-containing protein	M1NSC5	Streptococcus_phage	2.7e-113	98.6

DBSCAN-SWA_5

1428241 : 1447203

Streptococcus_phage(86.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_074389295.1\|1428241_1430068_-	polysaccharide biosynthesis protein	A0A1V0SAI8	Catovirus	2.7e-25	27.1
WP_013730278.1\|1430097_1430829_-	tyrosine protein phosphatase	NA	NA	NA	NA
WP_013730277.1\|1430867_1431554_-	tyrosine-protein kinase	A0A1X9I5D6	Streptococcus_phage	1.1e-104	92.1
WP_013730276.1\|1431563_1432253_-	capsular polysaccharide biosynthesis protein CpsC	A0A1X9I5E1	Streptococcus_phage	8.0e-108	92.1
WP_024383682.1\|1432268_1433708_-	LCP family protein	A0A1X9I5X1	Streptococcus_phage	1.5e-201	87.8
WP_074389294.1\|1433837_1434572_-	peroxide stress protein YaaA	A0A1X9I5I0	Streptococcus_phage	3.8e-116	95.8
WP_024383681.1\|1434694_1435954_+	PLP-dependent aminotransferase family protein	A0A1X9I5H2	Streptococcus_phage	2.3e-241	99.5
WP_024377015.1\|1436052_1436904_-	DegV family protein	A0A1X9I5J4	Streptococcus_phage	9.2e-154	99.3
WP_014638266.1\|1437030_1437435_+	TetR/AcrR family transcriptional regulator	A0A1X9I6A2	Streptococcus_phage	2.1e-63	97.8
WP_074389293.1\|1437457_1438243_-	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	2.1e-128	94.6
WP_074389292.1\|1438252_1439491_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.5e-221	98.8
WP_074389291.1\|1439555_1440632_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	2.8e-192	98.9
WP_171840883.1\|1440791_1443305_-	bifunctional DnaQ family exonuclease/ATP-dependent helicase	A0A1X9I5C8	Streptococcus_phage	0.0e+00	98.9
WP_009909540.1\|1443367_1444006_+	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	4.6e-126	100.0
WP_024378560.1\|1444145_1444619_-\|transposase	IS200/IS605 family transposase	D9CGB6	Hyperthermophilic_Archaeal_Virus_2	7.4e-12	35.1
WP_074389279.1\|1446039_1447203_+\|transposase	IS110 family transposase	A0A1X9I5G9	Streptococcus_phage	2.6e-26	92.4

DBSCAN-SWA_6

1614022 : 1628252

Streptococcus_phage(81.25%)

integrase

attL 1617521:1617554|attR 1628804:1628837

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014636692.1\|1614022_1615405_-	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L4K9	Tupanvirus	7.2e-31	37.8
WP_074389140.1\|1615581_1616052_-	ASCH domain-containing protein	NA	NA	NA	NA
WP_074389141.1\|1616048_1616600_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_074389142.1\|1616612_1617311_-	3-oxoacyl-ACP reductase	NA	NA	NA	NA
WP_004194840.1\|1617303_1617540_-	DUF2829 domain-containing protein	NA	NA	NA	NA
1617521:1617554	attL	NA	NA	NA	NA
WP_023370979.1\|1617635_1618781_-\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	9.6e-98	50.0
WP_023370981.1\|1619173_1619905_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_023370983.1\|1620068_1620266_+	helix-turn-helix transcriptional regulator	A0A1X9I5U5	Streptococcus_phage	2.6e-19	73.8
WP_023370985.1\|1620276_1620897_+	Rha family transcriptional regulator	A0A192Y918	Salmonella_phage	9.7e-12	30.0
WP_023370987.1\|1621282_1621558_+	hypothetical protein	A0A1X9I5W5	Streptococcus_phage	1.1e-36	90.1
WP_041179484.1\|1621547_1621778_+	hypothetical protein	A0A1X9I5V6	Streptococcus_phage	9.1e-24	86.6
WP_041179485.1\|1621737_1621935_+	hypothetical protein	NA	NA	NA	NA
WP_023370991.1\|1621938_1622145_+	hypothetical protein	A0A1X9I725	Streptococcus_phage	9.9e-22	81.8
WP_023370993.1\|1622205_1622556_+	hypothetical protein	NA	NA	NA	NA
WP_041179486.1\|1622548_1622821_+	DNA-binding protein	A0A1X9I5U9	Streptococcus_phage	2.0e-22	57.0
WP_023370995.1\|1622817_1623681_+	primase C-terminal domain-containing protein	A0A1X9I6L2	Streptococcus_phage	4.4e-111	68.8
WP_023370997.1\|1623677_1625201_+	phage/plasmid primase, P4 family, C-terminal domain protein	Q9AZI5	Lactococcus_phage	2.6e-74	41.9
WP_023370999.1\|1625535_1625976_+	hypothetical protein	A0A1X9I5V5	Streptococcus_phage	2.7e-72	97.3
WP_023371001.1\|1626045_1626546_+	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	1.0e-80	86.1
WP_023371003.1\|1626686_1627073_+	hypothetical protein	A0A1X9I5X3	Streptococcus_phage	1.3e-59	99.2
WP_009910449.1\|1627256_1627439_+	type II toxin-antitoxin system HicA family toxin	A0A1X9I5W4	Streptococcus_phage	3.7e-28	100.0
WP_023371005.1\|1627478_1627931_+	type II toxin-antitoxin system HicB family antitoxin	A0A1X9I727	Streptococcus_phage	3.8e-82	99.3
WP_023371007.1\|1628042_1628252_+	hypothetical protein	A0A1X9I6N3	Streptococcus_phage	3.9e-34	98.6
1628804:1628837	attR	NA	NA	NA	NA

DBSCAN-SWA_7

2008174 : 2111545

111

Streptococcus_phage(78.85%)

tail,tRNA,protease,terminase,holin,head,capsid,transposase,portal,integrase

attL 2063046:2063068|attR 2101986:2102008

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_171841224.1\|2008174_2009467_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	2.0e-216	95.2
WP_074389070.1\|2010395_2013515_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_012027852.1\|2013594_2014461_+	Hsp33 family molecular chaperone HslO	NA	NA	NA	NA
WP_074389071.1\|2014453_2015437_+\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_024388245.1\|2015785_2016028_-	hypothetical protein	NA	NA	NA	NA
WP_024388244.1\|2016024_2016258_-	hypothetical protein	NA	NA	NA	NA
WP_024416526.1\|2016277_2016661_-	hypothetical protein	NA	NA	NA	NA
WP_074389072.1\|2016849_2017350_-	adenylyltransferase/cytidyltransferase family protein	A0A291I9M1	Lactobacillus_phage	3.1e-24	39.7
WP_074389073.1\|2017468_2019922_-\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	1.2e-124	40.4
WP_002937810.1\|2019925_2020384_-	CtsR family transcriptional regulator	NA	NA	NA	NA
WP_074389074.1\|2020653_2020992_+	glutaredoxin family protein	NA	NA	NA	NA
WP_074389075.1\|2020991_2021618_+	GNAT family acetyltransferase	NA	NA	NA	NA
WP_029943831.1\|2022167_2023208_-	elongation factor Ts	NA	NA	NA	NA
WP_024381114.1\|2023361_2024138_-	30S ribosomal protein S2	NA	NA	NA	NA
WP_013730593.1\|2024484_2024997_-	adenylate kinase	NA	NA	NA	NA
WP_074389076.1\|2025650_2030729_-	S8 family serine peptidase	NA	NA	NA	NA
WP_002940254.1\|2030874_2031414_-	transcription termination/antitermination protein NusG	G3MAW2	Bacillus_virus	3.5e-10	28.2
WP_002940255.1\|2031523_2031700_-	preprotein translocase subunit SecE	NA	NA	NA	NA
WP_002940258.1\|2031709_2031862_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_074389077.1\|2031895_2034109_-	penicillin-binding protein	NA	NA	NA	NA
WP_014736452.1\|2034261_2035230_+	NAD(P)/FAD-dependent oxidoreductase	Q9JRK7	Streptococcus_phage	7.2e-46	69.4
WP_074389078.1\|2035231_2036095_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_044759976.1\|2036149_2036401_-	hypothetical protein	NA	NA	NA	NA
WP_029173255.1\|2036402_2036747_-	hypothetical protein	NA	NA	NA	NA
WP_074389079.1\|2036886_2038290_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_044674729.1\|2038286_2038754_-	hypothetical protein	NA	NA	NA	NA
WP_074389080.1\|2038746_2040966_-	peptidase domain-containing ABC transporter	W8CYL7	Bacillus_phage	1.9e-41	26.3
WP_074389081.1\|2041237_2042107_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_044776551.1\|2042201_2043014_-	pur operon repressor	A0A1V0SKE5	Klosneuvirus	1.4e-05	24.7
WP_074389082.1\|2043115_2043982_-	phosphotransferase	NA	NA	NA	NA
WP_002938440.1\|2043981_2044923_-	HD domain-containing protein	NA	NA	NA	NA
WP_074389083.1\|2044912_2046154_-	DNA recombination protein RmuC	NA	NA	NA	NA
WP_074389084.1\|2046154_2046787_-	thiamine diphosphokinase	NA	NA	NA	NA
WP_074389085.1\|2046779_2047439_-	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
WP_024403403.1\|2047453_2048329_-	ribosome small subunit-dependent GTPase A	NA	NA	NA	NA
WP_074389086.1\|2048955_2050533_-	ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.9e-19	32.5
WP_074389087.1\|2050989_2053434_-	alkaline phosphatase family protein	NA	NA	NA	NA
WP_012775361.1\|2053446_2055177_-	membrane protein	NA	NA	NA	NA
WP_012027884.1\|2055541_2056450_-	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	NA	NA	NA	NA
WP_009910909.1\|2056433_2056964_-	DUF1697 domain-containing protein	NA	NA	NA	NA
WP_012775363.1\|2056977_2057235_-	Txe/YoeB family addiction module toxin	NA	NA	NA	NA
WP_002939010.1\|2057236_2057497_-	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_012028534.1\|2057572_2058028_-	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
WP_012775364.1\|2058034_2058364_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_012028535.1\|2058353_2058641_-	hypothetical protein	NA	NA	NA	NA
WP_012775453.1\|2058738_2059107_-	hypothetical protein	NA	NA	NA	NA
WP_012775700.1\|2059099_2059669_-	ribonuclease M5	NA	NA	NA	NA
WP_012028536.1\|2059652_2060435_-	TatD family hydrolase	NA	NA	NA	NA
WP_002939016.1\|2060541_2060679_-	50S ribosomal protein L34	NA	NA	NA	NA
WP_012775367.1\|2060846_2061842_-	protein jag	NA	NA	NA	NA
WP_012027897.1\|2061861_2062674_-	membrane protein insertase YidC	NA	NA	NA	NA
WP_004194560.1\|2062657_2063017_-	ribonuclease P protein component	NA	NA	NA	NA
2063046:2063068	attL	NA	NA	NA	NA
WP_161945198.1\|2063466_2064759_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	5.2e-217	95.5
WP_074393835.1\|2064967_2065687_-	SH3 domain-containing protein	M1PKF8	Streptococcus_phage	6.4e-132	95.8
WP_074393836.1\|2065670_2066021_-\|holin	phage holin	A0A1X9I630	Streptococcus_phage	5.2e-47	85.3
WP_044770749.1\|2066031_2066367_-	hypothetical protein	M1PKM1	Streptococcus_phage	7.3e-22	100.0
WP_074411458.1\|2066370_2066709_-	hypothetical protein	A0A1X9I644	Streptococcus_phage	5.4e-57	91.1
WP_074392424.1\|2066711_2066930_-	hypothetical protein	A1EAB3	Streptococcus_phage	1.0e-24	97.0
WP_074393979.1\|2072368_2073211_-\|tail	phage tail protein	A7J2A6	Streptococcus_phage	7.8e-81	53.2
WP_074393978.1\|2073222_2077845_-\|tail	phage tail tape measure protein	A8ATA7	Listeria_phage	6.1e-58	38.5
WP_074393977.1\|2077854_2078124_-	hypothetical protein	D2IYX5	Enterococcus_phage	4.5e-06	41.1
WP_074393976.1\|2078162_2078642_-	hypothetical protein	A7J2A3	Streptococcus_phage	1.4e-26	40.6
WP_074393975.1\|2078699_2079302_-\|tail	phage major tail protein, TP901-1 family	A7J2A2	Streptococcus_phage	2.3e-58	63.7
WP_074393974.1\|2079314_2079674_-	hypothetical protein	A7J2A1	Streptococcus_phage	7.0e-31	52.1
WP_074393973.1\|2079680_2080025_-	hypothetical protein	A7J2A0	Streptococcus_phage	6.5e-26	53.5
WP_074393972.1\|2080021_2080300_-	hypothetical protein	A7J299	Streptococcus_phage	6.2e-19	48.9
WP_074393971.1\|2080309_2080666_-\|head,tail	phage head-tail connector protein	A7J298	Streptococcus_phage	4.4e-33	59.0
WP_074393970.1\|2080685_2081570_-\|capsid	phage capsid protein	A7J297	Streptococcus_phage	4.5e-111	70.2
WP_074393969.1\|2081571_2082147_-	DUF4355 domain-containing protein	A7J296	Streptococcus_phage	2.7e-40	61.2
WP_074393968.1\|2082282_2082495_-	hypothetical protein	NA	NA	NA	NA
WP_074393967.1\|2082599_2082851_-	hypothetical protein	A1EAE7	Streptococcus_phage	1.6e-37	92.8
WP_074393966.1\|2083144_2083360_-	hypothetical protein	NA	NA	NA	NA
WP_074393965.1\|2083349_2084711_-\|capsid	minor capsid protein	A7J293	Streptococcus_phage	7.4e-105	61.0
WP_079848616.1\|2084691_2086140_-\|portal	phage portal protein	A7J292	Streptococcus_phage	1.8e-173	62.5
WP_074393963.1\|2086210_2087497_-\|terminase	PBSX family phage terminase large subunit	A7J291	Streptococcus_phage	6.6e-196	79.5
WP_074393962.1\|2087480_2087915_-\|terminase	terminase small subunit	A7J290	Streptococcus_phage	1.9e-46	67.1
WP_074411824.1\|2088342_2088765_-	DUF1492 domain-containing protein	A0A141E1Y4	Streptococcus_phage	4.8e-63	87.9
WP_002937919.1\|2088839_2089091_-	hypothetical protein	M1PFL8	Streptococcus_phage	1.7e-39	100.0
WP_074403822.1\|2089102_2089372_-	hypothetical protein	M1NS18	Streptococcus_phage	2.5e-41	96.6
WP_002937925.1\|2089371_2089548_-	hypothetical protein	M1PS40	Streptococcus_phage	5.7e-26	100.0
WP_074403823.1\|2089547_2089730_-	hypothetical protein	M1Q1F5	Streptococcus_phage	3.3e-05	96.0
WP_074403824.1\|2089730_2090051_-	VRR-NUC domain-containing protein	A0A1X9I642	Streptococcus_phage	2.1e-42	84.3
WP_074403825.1\|2090031_2090904_-	bifunctional DNA primase/polymerase	A0A1P8BM82	Lactococcus_phage	2.1e-108	66.3
WP_074403826.1\|2091181_2092732_-	phage resistance protein	A0A1P8BM51	Lactococcus_phage	4.5e-191	65.4
WP_074403827.1\|2092748_2093219_-	DUF669 domain-containing protein	A0A1P8BM40	Lactococcus_phage	3.6e-59	71.6
WP_074403829.1\|2094663_2094906_-	hypothetical protein	NA	NA	NA	NA
WP_074403830.1\|2094908_2095586_-	AAA family ATPase	A0A286QRE1	Streptococcus_phage	1.1e-98	75.7
WP_074403831.1\|2095582_2095885_-	hypothetical protein	A0A1X9I668	Streptococcus_phage	5.7e-34	74.0
WP_074403832.1\|2095881_2096070_-	hypothetical protein	A0A1X9I6H6	Streptococcus_phage	1.0e-25	87.1
WP_074403844.1\|2096066_2096411_-	hypothetical protein	A0A1X9I636	Streptococcus_phage	1.1e-20	50.0
WP_156721194.1\|2096546_2096693_-	hypothetical protein	A0A1X9I650	Streptococcus_phage	9.2e-14	77.1
WP_074403833.1\|2096682_2096922_-	hypothetical protein	A0A1X9I6Q0	Streptococcus_phage	3.4e-13	56.8
WP_079846049.1\|2096946_2097210_-	hypothetical protein	C5J985	Streptococcus_phage	2.9e-10	38.3
WP_074403834.1\|2097334_2097544_+	hypothetical protein	NA	NA	NA	NA
WP_074403835.1\|2097522_2097717_-	hypothetical protein	NA	NA	NA	NA
WP_074403836.1\|2097730_2097952_-	helix-turn-helix transcriptional regulator	A0A141E0W0	Streptococcus_phage	3.1e-29	95.7
WP_074392470.1\|2097958_2098141_-	helix-turn-helix transcriptional regulator	A0A1X9I6I3	Streptococcus_phage	9.4e-08	49.2
WP_024377139.1\|2098277_2098502_+	DUF2188 domain-containing protein	E8ZD70	Streptococcus_phage	3.7e-22	67.6
WP_171840882.1\|2098498_2098639_-	hypothetical protein	NA	NA	NA	NA
WP_141668680.1\|2098831_2099611_+	helix-turn-helix domain-containing protein	M1PKS2	Streptococcus_phage	6.3e-101	74.9
WP_074403840.1\|2099630_2100500_+	hypothetical protein	A1EAB8	Streptococcus_phage	1.7e-155	94.1
WP_074403841.1\|2100678_2101845_+\|integrase	site-specific integrase	A0A141E0Q7	Streptococcus_phage	9.2e-80	42.7
WP_012027899.1\|2102027_2103422_-	argininosuccinate lyase	NA	NA	NA	NA
2101986:2102008	attR	NA	NA	NA	NA
WP_074389088.1\|2103435_2104629_-	argininosuccinate synthase	NA	NA	NA	NA
WP_012775368.1\|2104821_2105370_-	hypothetical protein	NA	NA	NA	NA
WP_014638731.1\|2105439_2105967_-	transcription repressor NadR	NA	NA	NA	NA
WP_074389089.1\|2106072_2106948_-	VOC family protein	NA	NA	NA	NA
WP_024408024.1\|2107068_2107569_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_012775454.1\|2107618_2108566_-	homocysteine S-methyltransferase	NA	NA	NA	NA
WP_074389090.1\|2108578_2109955_-	amino acid permease	NA	NA	NA	NA
WP_044670499.1\|2110090_2111545_-\|tRNA	glutamate--tRNA ligase	NA	NA	NA	NA

DBSCAN-SWA_8

2124445 : 2179084

Leptospira_phage(25.0%)

protease,transposase,tRNA,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012027923.1\|2124445_2125123_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_074389093.1\|2125106_2125649_-	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_024403069.1\|2125689_2126817_-	N-acetyldiaminopimelate deacetylase	NA	NA	NA	NA
WP_024403068.1\|2126826_2127525_-	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase	NA	NA	NA	NA
WP_161945197.1\|2127792_2129085_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	2.0e-216	95.2
WP_012027929.1\|2129422_2129890_-	hypothetical protein	NA	NA	NA	NA
WP_012775375.1\|2130525_2131266_-	serine/threonine protein phosphatase	A0A0C5JZB3	Enterococcus_phage	6.1e-29	33.5
WP_012775376.1\|2131331_2132681_-	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_074389385.1\|2132762_2133281_-	hypothetical protein	NA	NA	NA	NA
WP_141666531.1\|2133343_2134190_+\|transposase	IS630 family transposase	S5VXX4	Leptospira_phage	6.8e-08	25.1
WP_012027934.1\|2134473_2134995_-\|tRNA	tRNA adenosine(34) deaminase TadA	NA	NA	NA	NA
WP_012775378.1\|2135274_2137245_-	transketolase	NA	NA	NA	NA
WP_141666531.1\|2137385_2138233_-\|transposase	IS630 family transposase	S5VXX4	Leptospira_phage	6.8e-08	25.1
WP_002938500.1\|2138354_2139446_-	L-ascorbate 6-phosphate lactonase	NA	NA	NA	NA
WP_024383971.1\|2139555_2141244_-	transcription antiterminator	NA	NA	NA	NA
WP_012775380.1\|2141368_2141986_-	hypothetical protein	NA	NA	NA	NA
WP_023371743.1\|2142070_2142787_-	L-ribulose-5-phosphate 4-epimerase	NA	NA	NA	NA
WP_023371745.1\|2142786_2143650_-	L-ribulose-5-phosphate 3-epimerase	NA	NA	NA	NA
WP_023371747.1\|2143655_2144318_-	3-keto-L-gulonate-6-phosphate decarboxylase UlaD	NA	NA	NA	NA
WP_012027941.1\|2144328_2144814_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_009910950.1\|2144876_2145155_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_024393386.1\|2145213_2146662_-	PTS ascorbate transporter subunit IIC	NA	NA	NA	NA
WP_161945208.1\|2146989_2153274_-	pullulanase	NA	NA	NA	NA
WP_002939863.1\|2153455_2154397_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_023371756.1\|2154761_2155508_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-35	42.0
WP_002938543.1\|2155517_2156177_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_012027948.1\|2156189_2156993_-	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_161945209.1\|2157140_2157692_-	CHAP domain-containing protein	NA	NA	NA	NA
WP_023371763.1\|2158017_2159394_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_023371765.1\|2159437_2159878_-	DUF3284 domain-containing protein	NA	NA	NA	NA
WP_023371767.1\|2159896_2160211_-	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
WP_014638782.1\|2160212_2160524_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_024405426.1\|2160536_2162531_-	BglG family transcription antiterminator	NA	NA	NA	NA
WP_024405427.1\|2162622_2163729_-	DUF871 domain-containing protein	NA	NA	NA	NA
WP_024405428.1\|2163738_2165139_-	glycoside hydrolase family 1 protein	NA	NA	NA	NA
WP_014638786.1\|2165135_2166497_-	6-phospho-beta-glucosidase	NA	NA	NA	NA
WP_012775383.1\|2166671_2169173_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	65.0
WP_012027960.1\|2169275_2171168_-	metalloendopeptidase	E3T4I7	Cafeteria_roenbergensis_virus	2.4e-69	30.6
WP_012775384.1\|2171223_2172063_-	metal ABC transporter permease	NA	NA	NA	NA
WP_012775385.1\|2172055_2172916_-	metal ABC transporter permease	NA	NA	NA	NA
WP_009910969.1\|2172908_2173679_-	metal ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.4e-12	30.1
WP_012775387.1\|2174232_2175156_-	zinc ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_012027964.1\|2175281_2175941_+	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_014636530.1\|2175976_2176252_-	hypothetical protein	NA	NA	NA	NA
WP_012775389.1\|2176349_2177024_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_024403054.1\|2178123_2178267_-\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_171840887.1\|2178379_2178565_-	hypothetical protein	NA	NA	NA	NA
WP_012027970.1\|2178640_2179084_-\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA

DBSCAN-SWA_9

2265211 : 2281584

Streptococcus_phage(68.75%)

integrase

attL 2266624:2266644|attR 2278216:2278236

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012028048.1\|2265211_2266465_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	1.1e-232	99.3
2266624:2266644	attL	NA	NA	NA	NA
WP_074389570.1\|2266885_2267281_-	DUF1492 domain-containing protein	NA	NA	NA	NA
WP_044752435.1\|2267237_2267657_-	hypothetical protein	NA	NA	NA	NA
WP_074389571.1\|2268136_2268679_-	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	9.3e-51	58.6
WP_162841090.1\|2268699_2268873_-	hypothetical protein	A0A1X9I5U0	Streptococcus_phage	5.8e-07	56.1
WP_074389573.1\|2269187_2270624_-	DNA primase	Q9AZI5	Lactococcus_phage	2.8e-62	37.7
WP_074403919.1\|2270686_2271565_-	primase C-terminal domain-containing protein	A0A1X9I6L2	Streptococcus_phage	6.4e-118	69.7
WP_171840765.1\|2271566_2271713_-	hypothetical protein	A0A1X9I5Y0	Streptococcus_phage	1.3e-15	93.5
WP_074389577.1\|2271699_2271984_-	transcriptional regulator	A0A1X9I5U9	Streptococcus_phage	2.5e-39	87.2
WP_074389597.1\|2271973_2272312_-	hypothetical protein	A0A1X9I5Z6	Streptococcus_phage	1.7e-42	88.0
WP_074389580.1\|2272652_2273042_-	hypothetical protein	NA	NA	NA	NA
WP_074389582.1\|2273510_2274137_-	Rha family transcriptional regulator	A0A192Y918	Salmonella_phage	1.0e-13	29.9
WP_074389584.1\|2274148_2274355_-	helix-turn-helix domain-containing protein	A0A1S5SE31	Streptococcus_phage	4.3e-09	59.6
WP_032538261.1\|2274393_2274588_-	helix-turn-helix transcriptional regulator	A0A1P8BKS6	Lactococcus_phage	8.2e-10	57.4
WP_029174017.1\|2274762_2275515_+	helix-turn-helix domain-containing protein	A0A1S5SC88	Streptococcus_phage	1.6e-48	41.7
WP_024381300.1\|2275806_2276811_+	virulence RhuM family protein	Q9JMN3	Wolbachia_phage	2.3e-79	47.7
WP_024381301.1\|2277040_2278213_+\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	9.2e-213	95.6
WP_012028049.1\|2278350_2278734_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	5.0e-35	85.0
2278216:2278236	attR	NA	NA	NA	NA
WP_012028050.1\|2278736_2279831_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_012028051.1\|2280102_2281584_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	2.1e-97	41.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LR738723

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection